John Hayball

Prof John Hayball

Professor

School of Pharmacy and Biomedical Science

College of Health

John is Research Professor in Immunology and Vaccinology, and heads Expertimental Therapeutics Laboratory within the Clinical and Health Sciences Division at UniSA. 
John's group perform basic, translational and clinical research that aims to improve chronic and acute health outcomes, by exploring novel immunotherapeutic approaches to treat and prevent acute and chronic infections, allergy and cancer.
John is focussed on cross-disciplinary collaboration leading to productive translational outcomes in human health, by strategically engaging with research academics, clinicians and industry partners to form integrated research programs with the capacity to address challenging health questions. He has a successful track record of research grant funding from the NHMRC, MRFF and ARC, as well as other National and International competative funding schemes.
He has a long history of biotechnology and pharmaceutical industry engagement, including executive, advisory and consultancies roles, and a track record of successful commercial collaborative and contractual research funding, and award of competative industry-leveraged federal and state government funding schemes.

  • Immunology and Inflammation
  • Vaccinology
  • Infectious Diseases
  • Allergy
  • Cancer Biology

Year Citation
2025 Alemie, M. N., Le, T. N., Nguyen, N. H., Truong, V. K., Vongsvivut, J., Palms, D., . . . Vasilev, K. (2025). Biomaterial surface-induced immunoglobulin G unfolding enhances phagocytosis of Staphylococcus Aureus by macrophages. Acta Biomaterialia, 208, 226-243.
DOI
2025 Alemie, M. N., Bright, R., Ninan, N., Dabare, P. R., Ngoc Le, T., Do, X. D., . . . Vasilev, K. (2025). Biomaterial Surface Nanotopography Induced IgG Unfolding Modulates Macrophage Innate Immune Responses. ACS Applied Materials and Interfaces, 17(35), 49286-49303.
DOI
2025 Alemie, M. N., Bright, R., Ninan, N., Ngoc Le, T., Nguyen, N. H., Truong, V. K., . . . Vasilev, K. (2025). Deciphering the Role of Biomaterial Surface Chemistry in Toll-Like Receptor-Mediated Immune Modulation. ACS Biomaterials Science and Engineering, 11(11), 6575-6592.
DOI
2024 Alemie, M. N., Bright, R., Nguyen, N. H., Truong, V. K., Palms, D., Hayball, J. D., & Vasilev, K. (2024). Surface Chemistry Induced IgG Unfolding and Modulation of Immune Responses. ACS Applied Materials and Interfaces, 16(38), 50507-50523.
DOI Scopus7 WoS6 Europe PMC7
2024 Wang, S., Qiao, X., Cui, Y., Liu, L., Cooper, T., Hu, Y., . . . Wang, X. (2024). NCAPH, ubiquitinated by TRIM21, promotes cell proliferation by inhibiting autophagy of cervical cancer through AKT/mTOR dependent signaling. Cell Death and Disease, 15(8), 16 pages.
DOI Scopus13 WoS13 Europe PMC12
2023 Dabare, P. R. L., Bachhuka, A., Quek, J. Y., Marsal, L. F., Hayball, J., & Vasilev, K. (2023). Nano-Roughness-Mediated Macrophage Polarization for Desired Host Immune Response. Small Science, 3(10), 10 pages.
DOI Scopus17 WoS17 Europe PMC9
2023 Li, W., Wang, W., Liu, L., Qu, R., Chen, X., Qiu, C., . . . Zhao, Y. (2023). GDF11 antagonizes TNF-a-induced inflammation and protects against the development of inflammatory arthritis in mice (vol 33, pg 3317, 2019). FASEB JOURNAL, 37(2), 3 pages.
DOI
2022 Zhang, Y., Liu, L., Pillman, K. A., Hayball, J., Su, Y. W., & Xian, C. J. (2022). Differentially expressed miRNAs in bone after methotrexate treatment. Journal of Cellular Physiology, 237(1), 965-982.
DOI Scopus4 WoS6 Europe PMC6
2022 Wang, S., Li, W., Zhang, P., Wang, Z., Ma, X., Liu, C., . . . Zhao, Y. (2022). Mechanical overloading induces GPX4-regulated chondrocyte ferroptosis in osteoarthritis via Piezo1 channel facilitated calcium influx. Journal of Advanced Research, 41, 63-75.
DOI Scopus190 WoS172 Europe PMC160
2022 Eldi, P., Cooper, T. H., Prow, N. A., Liu, L., Heinemann, G. K., Zhang, V. J., . . . Hayball, J. D. (2022). The vaccinia-based Sementis Copenhagen Vector coronavirus disease 2019 vaccine induces broad and durable cellular and humoral immune responses. Immunology and Cell Biology, 100(4), 250-266.
DOI Scopus4 WoS3 Europe PMC2
2022 Ruvini L Dabare, P., Bachhuka, A., Palms, D., Parkinson-Lawrence, E., Hayball, J. D., Mierczynska, A., & Vasilev, K. (2022). Surface chemistry mediated albumin adsorption, conformational changes and influence on innate immune responses. Applied Surface Science, 596(article no. 153518), 11 pages.
DOI Scopus22 WoS20
2021 Guzman-Genuino, R. M., Hayball, J. D., & Diener, K. R. (2021). Regulatory B cells: dark horse in pregnancy immunotherapy?. Journal of Molecular Biology, 433(1), 166596-1-166596-14.
DOI Scopus19 WoS14 Europe PMC13
2021 Hazlewood, J. E., Dumenil, T., Le, T. T., Slonchak, A., Kazakoff, S. H., Patch, A. M., . . . Suhrbier, A. (2021). Injection site vaccinology of a recombinant vaccinia-based vector reveals diverse innate immune signatures. PLoS Pathogens, 17(1), e1009215-1-e1009215-39.
DOI Scopus14 WoS14 Europe PMC16
2021 Yu, M., Teo, T., Yang, Y., Li, M., Long, Y., Philip, S., . . . Wang, S. (2021). Potent and orally bioavailable CDK8 inhibitors: design, synthesis, structure-activity relationship analysis and biological evaluation. European Journal of Medicinal Chemistry, 214, 1-22.
DOI Scopus14 WoS13 Europe PMC11
2020 Wang, M., Qiao, X., Cooper, T., Pan, W., Liu, L., Hayball, J., . . . Wang, X. (2020). HPV E7-mediated NCAPH ectopic expression regulates the carcinogenesis of cervical carcinoma via PI3K/AKT/SGK pathway. Cell Death and Disease, 11(12, article no. 1049), 1-16.
DOI Scopus34 WoS38 Europe PMC37
2020 Qu, R., Chen, X., Yuan, Y., Wang, W., Qiu, C., Liu, L., . . . Li, W. (2020). Correction to: Ghrelin Fights against Titanium Particle-Induced Inflammatory Osteolysis through Activation of β-Catenin Signaling Pathway (Inflammation, (2019), 42, 5, (1652-1665), 10.1007/s10753-019-01026-w). Inflammation, 43(3), 1170-1171.
DOI
2020 Day, J., Otto, S., Cash, K., Eldi, P., Hissaria, P., Proudman, S., . . . Hayball, J. D. (2020). Aberrant expression of high mobility group box protein 1 in the idiopathic inflammatory myopathies. Frontiers in Cell and Developmental Biology, 8(article no. 226 q 1), 11 pages.
DOI Scopus13 WoS14 Europe PMC14
2020 Garcia-Valtanen, P., van Diermen, B. A., Lakhan, N., Lousberg, E. L., Robertson, S. A., Hayball, J. D., & Diener, K. R. (2020). Maternal host responses to poly(I:C) during pregnancy leads to both dysfunctional immune profiles and altered behaviour in the offspring. American Journal of Reproductive Immunology, 84(2), 1-11.
DOI Scopus18 WoS18 Europe PMC14
2020 Garcia-Valtanen, P., Guzman-Genuino, R. M., Hayball, J. D., & Diener, K. R. (2020). Polyinosinic: polycytidylic acid and murine cytomegalovirus modulate expression of murine IL-10 and IL-21 in white adipose tissue. Viruses, 12(5), 569-1-569-16.
DOI Scopus4 WoS2 Europe PMC3
2020 Nguyen, W., Nakayama, E., Yan, K., Tang, B., Le, T. T., Liu, L., . . . Suhrbier, A. (2020). Arthritogenic alphavirus vaccines: serogrouping versus cross-protection in mouse models. Vaccines, 8(2), 209-1-209-26.
DOI Scopus35 WoS35 Europe PMC38
2020 Prow, N. A., Liu, L., McCarthy, M. K., Walters, K., Kalkeri, R., Geiger, J., . . . Suhrbier, A. (2020). The vaccinia virus based Sementis Copenhagen Vector vaccine against Zika and chikungunya is immunogenic in non-human primates. NPJ Vaccines, 5(1, article no. 44), 44-1-44-10.
DOI Scopus21 WoS16 Europe PMC17
2020 Zhao, Y., Qiu, C., Wang, W., Peng, J., Vasilev, K., Liu, L., . . . Li, W. (2020). Cortistatin protects against intervertebral disc degeneration through targeting mitochondrial ROS-dependent NLRP3 inflammasome activation. Theranostics, 10(15), 7015-7033.
DOI Scopus138 WoS129 Europe PMC110
2019 Visalakshan, R. M., MacGregor, M. N., Sasidharan, S., Ghazaryan, A., Mierczynska-Vasilev, A. M., Morsbach, S., . . . Vasilev, K. (2019). Biomaterial surface hydrophobicity-mediated serum protein adsorption and immune responses. ACS Applied Materials and Interfaces, 11(31), 27615-27623.
DOI Scopus178 WoS171 Europe PMC117
2019 Eldi, P., Cooper, T., Ward, M., & Hayball, J. D. (2019). How emerging vaccine technologies are pushing disease prevention boundaries. International pharmacy journal, 37(1), 16-19.
2019 Guzman-Genuino, R. M., Dimova, T., You, Y., Aldo, P., Hayball, J. D., Mor, G., & Diener, K. R. (2019). Trophoblasts promote induction of a regulatory phenotype in B cells that can protect against detrimental T cell-mediated inflammation. American Journal of Reproductive Immunology, 82(6), e13187-1-e13187-16.
DOI Scopus17 WoS15 Europe PMC12
2019 Stevens, N. E., Nash, C. H., Fraser, C. K., Kuchel, T. R., Maiden, M. J., Chapman, M. J., . . . Hayball, J. D. (2019). High mobility group box protein 1 neutralization therapy in ovine bacteremia: lessons learned from an ovine septic shock model incorporating intensive care support. Experimental and Therapeutic Medicine, 18(5), 3271-3280.
DOI WoS1 Europe PMC1
2019 Afinjuomo, F., Barclay, T. G., Parikh, A., Chung, R., Song, Y., Nagalingam, G., . . . Garg, S. (2019). Synthesis and characterization of pH-sensitive inulin conjugate of isoniazid for monocyte-targeted delivery. Pharmaceutics, 11(11), 555-1-555-19.
DOI Scopus21 WoS20 Europe PMC10
2019 Pincher, D. W. M., Bader, C. A., Hayball, J. D., Plush, S. E., & Sweetman, M. J. (2019). Graphene quantum dot embedded hydrogel for dissolved iron sensing. ChemistrySelect, 4(33), 9640-9646.
DOI Scopus18 WoS17
2019 Wang, L., Song, Y., Parikh, A., Joyce, P., Chung, R., Liu, L., . . . Garg, S. (2019). Doxorubicin-loaded delta inulin conjugates for controlled and targeted drug delivery: development, characterization, and in vitro evaluation. Pharmaceutics, 11(11), 581-1-581-17.
DOI Scopus30 WoS25 Europe PMC19
2019 Grubor-Bauk, B., Wijesundara, D. K., Masavuli, M., Abbink, P., Peterson, R. L., Prow, N. A., . . . Gowans, E. J. (2019). NS1 DNA vaccination protects against Zika infection through T cell-mediated immunity in immunocompetent mice.. Sci Adv, 5(12), eaax2388.
DOI Scopus65 WoS56 Europe PMC54
2019 Guzman-Genuino, R. M., Eldi, P., Garcia-Valtanen, P., Hayball, J. D., & Diener, K. R. (2019). Uterine B cells exhibit regulatory properties during the peri-implantation stage of murine pregnancy. Frontiers in Immunology, 10(2899), 2899-1-2899-12.
DOI Scopus22 WoS19 Europe PMC16
2019 Lundquist, N., Sweetman, M. J., Scroggie, K. R., Worthington, M. J. H., Esdaile, L. J., Alboaiji, S. F. K., . . . Chalker, J. M. (2019). Polymer supported carbon for safe and effective remediation of PFOA- and PFOS-contaminated water. ACS sustainable chemistry & engineering, 7(13), 11044-11049.
DOI Scopus55 WoS50
2019 Afinjuomo, F., Barclay, T. G., Parikh, A., Song, Y., Chung, R., Wang, L., . . . Garg, S. (2019). Design and characterization of inulin conjugate for improved intracellular and targeted delivery of pyrazinoic acid to monocytes. Pharmaceutics, 11(5), 243-1-243-22.
DOI Scopus13 WoS9 Europe PMC9
2019 Li, W., Wang, W., Liu, L., Qu, R., Chen, X., Qiu, C., . . . Zhao, Y. (2019). GDF11 antagonizes TNF-α-induced inflammation and protects against the development of inflammatory arthritis in mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(3), 3317-3329.
DOI Scopus35 WoS34 Europe PMC30
2019 Garcia, L. E. G., MacGregor, M. N., Visalakshan, R. M., Ninan, N., Cavallaro, A. A., Trinidad, A. D., . . . Vasilev, K. (2019). Self-sterilizing antibacterial silver-loaded microneedles. Chemical Communications, 55(2), 171-174.
DOI Scopus75 WoS77 Europe PMC47
2019 Visalakshan, R. M., Cavallaro, A. A., MacGregor, M. N., Lawrence, E. P., Koynov, K., Hayball, J. D., & Vasilev, K. (2019). Nanotopography-induced unfolding of fibrinogen modulates leukocyte binding and activation. Advanced Functional Materials, 29(14), 1807453-1-1807453-12.
DOI Scopus43 WoS44
2019 Sweetman, M. J., Hickey, S. M., Brooks, D. A., Hayball, J. D., & Plush, S. E. (2019). A Practical Guide to Prepare and Synthetically Modify Graphene Quantum Dots. Advanced Functional Materials, 29(14), 18 pages.
DOI Scopus100 WoS98
2019 Zhao, Y., Li, Y., Qu, R., Chen, X., Wang, W., Qiu, C., . . . Li, W. (2019). Cortistatin binds to TNF-α receptors and protects against osteoarthritis. EBioMedicine, 41, 556-570.
DOI Scopus69 WoS62 Europe PMC49
2019 Qu, R., Chen, X., Yuan, Y., Wang, W., Qiu, C., Liu, L., . . . Li, W. (2019). Ghrelin fights against titanium particle-induced inflammatory osteolysis through activation of β-catenin signaling pathway. Inflammation, 42(5), 1652-1665.
DOI Scopus12 WoS12 Europe PMC10
2019 Moldenhauer, L. M., Schjenken, J. E., Hope, C. M., Green, E. S., Zhang, B., Eldi, P., . . . Robertson, S. A. (2019). Thymus-derived regulatory T cells exhibit Foxp3 epigenetic modification and phenotype attenuation after mating in mice. Journal of Immunology, 203(3), 647-657.
DOI Scopus34 WoS32 Europe PMC33
2018 Lynch, J., Werder, R., Loh, Z., Sikder, M., Curren, B., Zhang, V., . . . Phipps, S. (2018). Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion. Journal of Experimental Medicine, 215(2), 537-557.
DOI Scopus68 WoS64 Europe PMC61
2018 Zhang, W., Song, Y., Eldi, P., Guo, X., Hayball, J., Garg, S., & Albrecht, H. (2018). Targeting prostate cancer cells with hybrid elastin-like polypeptide/liposome nanoparticles. International Journal of Nanomedicine, 13, 293-305.
DOI Scopus47 WoS36 Europe PMC24
2018 Prow, N., Liu, L., Nakayama, E., Cooper, T., Yan, K., Eldi, P., . . . Suhrbier, A. (2018). A vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya viruses. Nature Communications, 9(1), 1230-1-1230-12.
DOI Scopus72 WoS68 Europe PMC66
2018 Ferrand, J., Croft, N., Pépin, G., Diener, K., Wu, D., Mangan, N., . . . Gantier, M. (2018). The use of CRISPR/Cas9 gene editing to confirm congenic contaminations in host-pathogen interaction studies. Frontiers in Cellular and Infection Microbiology, 8(article no. 87), 87-1-87-10.
DOI Scopus2 WoS2 Europe PMC2
2018 Gillam, T., Sweetman, M., Bader, C., Morrison, J., Hayball, J., Brooks, D., & Plush, S. (2018). Bright lights down under: metal ion complexes turning the spotlight on metabolic processes at the cellular level. Coordination Chemistry Reviews, 375, 234-255.
DOI Scopus9 WoS7
2018 Sweetman, M. J., Sebben, D., Noll, B. D., Wang, W. H., May, S., Mebberson, N., . . . Hayball, J. D. (2018). A rapid technique to determine performance and efficiency of activated carbon water filters. Water science and technology: water supply, 18(2), 371-382.
DOI Scopus10 WoS9
2018 Prow, N. A., Jimenez Martinez, R., Hayball, J. D., Howley, P. M., & Suhrbier, A. (2018). Poxvirus-based vector systems and the potential for multi-valent and multi-pathogen vaccines. Expert review of vaccines, 17(10), 925-934.
DOI Scopus37 WoS32 Europe PMC32
2018 Pavathuparambil Abdul Manaph, N., Al Hawwas, M., Liu, L., Liu, D., Hayball, J., & Zhou, X. F. (2018). Facial vein injection of human cells in severe combined immunodeficiency (SCID) neonatal mice. MethodsX, 5, 1281-1286.
DOI Scopus2 WoS2 Europe PMC4
2018 Visalakshan, R. M., Macgregor, M. N., Cavallaro, A. A., Sasidharan, S., Bachhuka, A., Mierczynska-Vasilev, A. M., . . . Vasilev, K. (2018). Creating nano-engineered biomaterials with well-defined surface descriptors. ACS Applied Nano Materials, 1(6), 2796-2807.
DOI Scopus36 WoS34
2017 Sweetman, M. J., May, S., Mebberson, N., Pendleton, P., Vasilev, K., Plush, S. E., & Hayball, J. (2017). Activated carbon, carbon nanotubes and graphene: materials and composites for advanced water purification. Journal of carbon research, 3(2), 1-29.
DOI WoS154
2017 Day, J., Limaye, V., Proudman, S., Hayball, J., & Hissaria, P. (2017). The utility of monitoring peripheral blood lymphocyte subsets by flow cytometric analysis in patients with rheumatological diseases treated with rituximab. Autoimmunity Reviews, 16(5), 542-547.
DOI Scopus7 WoS6 Europe PMC6
2017 Liu, L., Cooper, T., Eldi, P., Garcia-Valtanen, P., Diener, K., Howley, P., & Hayball, J. (2017). Transient dominant host-range selection using Chinese hamster ovary cells to generate marker-free recombinant viral vectors from Vaccinia virus. BioTechniques, 62(4), 183-187.
DOI Scopus4 WoS4 Europe PMC4
2017 Flies, A., Blackburn, N., Lyons, A., Hayball, J., & Woods, G. (2017). Comparative analysis of immune checkpoint molecules and their potential role in the transmissible Tasmanian Devil facial tumor disease. Frontiers in Immunology, 8(MAY), 513-1-513-27.
DOI Scopus15 WoS16 Europe PMC17
2017 Moldenhauer, L., Diener, K., Hayball, J., & Robertson, S. (2017). An immunogenic phenotype in paternal antigen-specific CD8⁺ T cells at embryo implantation elicits later fetal loss in mice. Immunology and Cell Biology, 95(8), 705-715.
DOI Scopus30 WoS29 Europe PMC27
2017 Eldi, P., Cooper, T., Liu, L., Prow, N., Diener, K., Howley, P., . . . Hayball, J. (2017). Production of a chikungunya vaccine using a CHO cell and attenuated viral-based platform technology. Molecular Therapy, 25(10), 2332-2344.
DOI Scopus19 WoS19 Europe PMC18
2017 Stevens, N., Chapman, M., Fraser, C., Kuchel, T., Hayball, J., & Diener, K. (2017). Therapeutic targeting of HMGB1 during experimental sepsis modulates the inflammatory cytokine profile to one associated with improved clinical outcomes. Scientific Reports, 7(1), 5850-1-5850-14.
DOI Scopus89 WoS90 Europe PMC82
2017 Wijesundara, D., Yu, W., Quah, B., Eldi, P., Hayball, J., Diener, K., . . . Grubor-Bauk, B. (2017). Cytolytic DNA vaccine encoding lytic perforin augments the maturation of- and antigen presentation by- dendritic cells in a time-dependent manner. Scientific Reports, 7(1), 8530-1-8530-8.
DOI Scopus8 WoS9 Europe PMC9
2017 Jæger, D., Ndi, C., Crocoll, C., Simpson, B., Khakimov, B., Guzman-Genuino, R., . . . Semple, S. (2017). Isolation and Structural Characterization of Echinocystic Acid Triterpenoid Saponins from the Australian Medicinal and Food Plant Acacia ligulata. Journal of Natural Products, 80(10), 2692-2698.
DOI Scopus18 WoS17 Europe PMC12
2017 Day, J., Otto, S., Proudman, S., Hayball, J. D., & Limaye, V. (2017). Dysregulated innate immune function in the aetiopathogenesis of idiopathic inflammatory myopathies. Autoimmunity Reviews, 16(1), 87-95.
DOI Scopus16 WoS16 Europe PMC14
2017 Bachhuka, A., Hayball, J., Smith, L., & Vasilev, K. (2017). The interplay between surface nanotopography and chemistry modulates collagen I and III deposition by human dermal fibroblasts. ACS Applied Materials and Interfaces, 9(7), 5874-5884.
DOI Scopus27 WoS27 Europe PMC18
2017 Garcia-Valtanen, P., Guzman-Genuino, R., Williams, D., Hayball, J., & Diener, K. (2017). Evaluation of trained immunity by β-1, 3 (D)-glucan on murine monocytes in vitro and duration of response in vivo. Immunology and Cell Biology, 95(7), 601-610.
DOI Scopus75 WoS71 Europe PMC68
2016 Lakhan, N., Stevens, N., Diener, K., & Hayball, J. (2016). CoVaccine HT™ adjuvant is superior to Freund's adjuvants in eliciting antibodies against the endogenous alarmin HMGB1. Journal of Immunological Methods, 439, 37-43.
DOI Scopus12 WoS12 Europe PMC15
2016 Flies, A., Lyons, A., Corcoran, L., Papenfuss, A., Murphy, J., Knowles, G., . . . Hayball, J. (2016). PD-L1 is not constitutively expressed on tasmanian devil facial tumor cells but is strongly upregulated in response to IFN-γ and can be expressed in the tumor microenvironment. Frontiers in Immunology, 7(581), 581-1-581-13.
DOI Scopus34 WoS33 Europe PMC33
2016 Gargett, T., Yu, W., Dotti, G., Yvon, E., Christo, S., Hayball, J., . . . Brown, M. (2016). GD2-specific CAR T cells undergo potent activation and deletion following antigen encounter but can be protected from activation-induced cell death by PD-1 blockade. Molecular Therapy, 24(6), 1135-1149.
DOI Scopus319 WoS295 Europe PMC276
2016 Flies, A. S., Woods, G. M., Lyons, A. B., & Hayball, J. D. (2016). Understanding the role of the PD-1 co-signalling pathway in the Tasmanian devil facial tumour disease. Integrative and comparative biology, 56(suppl 1), 66.
DOI
2016 Lynch, J., Rogers, M., Lane, K., Werder, R., Loh, Z., Diener, K., . . . Phipps, S. (2016). Uncoupling of the Pdc-Treg crosstalk during early-life pneumovirus infection underlies long-lived Treg dysfunction and asthma development. Respirology, 21, 121.
2016 Christo, S., Bachhuka, A., Diener, K., Vasilev, K., & Hayball, J. (2016). The contribution of inflammasome components on macrophage response to surface nanotopography and chemistry. Scientific Reports, 6(article no. 26207), 26207-1-26207-9.
DOI Scopus39 WoS39 Europe PMC25
2016 Nguyen, T., Arthur, A., Purton, L., Hayball, J., Zannettino, A., Paton, S., . . . Gronthos, S. (2016). EphB4 enhances bone marrow stromal stem cell-mediated support of haematopoiesis. British journal of haematology, 173(30, S1,S1), 30.
2016 Stevens, N., Hatjopolous, A., Fraser, C., Alsharifi, M., Diener, K., & Hayball, J. (2016). Preserved antiviral adaptive immunity following polyclonal antibody immunotherapy for severe murine influenza infection. Scientific Reports, 6(29154), 1-13.
DOI Scopus9 WoS9 Europe PMC7
2016 Zhang, W., Garg, S., Eldi, P., Zhou, F., Johnson, I., Brooks, D., . . . Albrecht, H. (2016). Targeting prostate cancer cells with genetically engineered polypeptide-based micelles displaying gastrin-releasing peptide. International Journal of Pharmaceutics, 513(1-2), 270-279.
DOI Scopus27 WoS25 Europe PMC17
2016 Tao, B., Bernardo, K., Eldi, P., Chegeni, N., Wiese, M., Colella, A., . . . Chataway, T. (2016). Extended boiling of peanut progressively reduces IgE allergenicity while retaining T cell reactivity. Clinical and Experimental Allergy, 46(7), 1004-1014.
DOI Scopus47 WoS41 Europe PMC27
2016 Fok, J. S., Kral, A. C., Hayball, J., & Smith, W. B. (2016). Marking nut anaphylaxis. ASIA PACIFIC ALLERGY, 6(3), 192-194.
DOI WoS4 Europe PMC2
2016 Diener, K., Robertson, S., Hayball, J., & Lousberg, E. (2016). Multi-parameter flow cytometric analysis of uterine immune cell fluctuations over the murine estrous cycle. Journal of Reproductive Immunology, 113, 61-67.
DOI Scopus19 WoS19 Europe PMC20
2016 Christo, S., Bachhuka, A., Diener, K., Mierczynska, A., Hayball, J., & Vasilev, K. (2016). The role of surface nanotopography and chemistry on primary neutrophil and macrophage cellular responses. Advanced Healthcare Materials, 5(8), 956-965.
DOI Scopus96 WoS94 Europe PMC63
2016 Christo, S., Diener, K., Manavis, J., Grimbaldeston, M., Bachhuka, A., Vasilev, K., & Hayball, J. (2016). Inflammasome components ASC and AIM2 modulate the acute phase of biomaterial implant-induced foreign body responses. Scientific Reports, 6(20635), 20635-1-20635-14.
DOI Scopus21 WoS19 Europe PMC15
2015 Taheri, S., Cavallaro, A., Christo, S., Majewski, P., Barton, M., Hayball, J., & Vasilev, K. (2015). Antibacterial plasma polymer films conjugated with phospholipid
encapsulated silver nanoparticles. ACS Biomaterials Science & Engineering, 1(12), 1278-1286.
DOI Scopus44 WoS40 Europe PMC17
2015 Ramiasa, M., Cavallaro, A., Mierczynska, A., Christo, S., Gleadle, J., Hayball, J., & Vasilev, K. (2015). Plasma polymerised polyoxazoline thin films for biomedical applications. Chemical Communications, 51(20), 4279-4282.
DOI Scopus90 WoS86 Europe PMC39
2015 Christo, S., Diener, K., & Hayball, J. (2015). The functional contribution of calcium ion flux heterogeneity in T cells. Immunology and Cell Biology, 93(8), 694-704.
DOI Scopus20 WoS21 Europe PMC18
2015 Mon, H., Christo, S., Ndi, C., Jasieniak, M., Rickard, H., Hayball, J., . . . Semple, S. (2015). Serrulatane Diterpenoid from Eremophila neglecta Exhibits Bacterial Biofilm Dispersion and Inhibits Release of Pro-inflammatory Cytokines from Activated Macrophages. Journal of Natural Products, 78(12), 3031-3040.
DOI Scopus22 WoS22 Europe PMC18
2015 Nguyen, T., Arthur, A., Panagopoulos, R., Paton, S., Hayball, J., Zannettino, A., . . . Gronthos, S. (2015). EphB4 expressing stromal cells exhibit an enhanced capacity for hematopoietic stem cell maintenance. Stem Cells, 33(9), 2838-2849.
DOI Scopus30 WoS31 Europe PMC26
2015 Bachhuka, A., Christo, S., Cavallaro, A., Diener, K., Mierczynska, A., Smith, L., . . . Vasilev, K. (2015). Hybrid core/shell microparticles and their use for understanding biological processes. Journal of Colloid and Interface Science, 457, 9-17.
DOI Scopus18 WoS18 Europe PMC9
2015 Christo, S., Diener, K., Bachhuka, A., Vasilev, K., & Hayball, J. (2015). Innate immunity and biomaterials at the Nexus: friends or foes. BioMed Research International, 2015(342304), 342304-1-342304-23.
DOI Scopus122 WoS112 Europe PMC94
2015 Nenke, M., Rankin, W., Chapman, M., Stevens, N., Diener, K., Hayball, J., . . . Torpy, D. (2015). Depletion of high affinity corticosteroid-binding globulin corresponds to illness severity in sepsis and septic shock; clinical implications. Clinical Endocrinology, 82(6), 801-807.
DOI Scopus52 WoS47 Europe PMC36
2015 Corrigan, F., Wu, Y., Tuke, J., Coller, J., Rice, K., Diener, K., . . . Hutchinson, M. (2015). Alcohol-induced sedation and synergistic interactions between alcohol and morphine: a key mechanistic role for Toll-like receptors and MyD88-dependent signaling. Brain, Behavior, and Immunity, 45, 245-252.
DOI Scopus22 WoS22 Europe PMC21
2015 Bachhuka, A., Hayball, J., Smith, L., & Vasilev, K. (2015). Effect of surface chemical functionalities on collagen deposition by primary human dermal fibroblasts. ACS applied materials & interfaces, 7(42), 23767-23775.
DOI Scopus32 WoS31 Europe PMC25
2015 Christo, S., Diener, K., Nordon, R., Brown, M., Griesser, H., Vasilev, K., . . . Hayball, J. (2015). Scrutinizing calcium flux oscillations in T lymphocytes to deduce the strength of stimulus. Scientific Reports, 5(article no. 7760), 7760-1-7760-8.
DOI Scopus26 WoS25 Europe PMC25
2014 Michl, T. D., Locock, K. E. S., Stevens, N. E., Hayball, J. D., Vasilev, K., Postma, A., . . . Griesser, H. J. (2014). RAFT-derived antimicrobial polymethacrylates: elucidating the impact of end-groups on activity and cytotoxicity. Polymer chemistry, 5(19), 5813-5822.
DOI Scopus81 WoS76
2014 Locock, K. E. S., Michl, T. D., Stevens, N., Hayball, J. D., Vasilev, K., Postma, A., . . . Haeussler, M. (2014). Antimicrobial polymethacrylates synthesized as mimics of tryptophan-rich cationic peptides. ACS Macro Letters, 3(4), 319-323.
DOI Scopus103 WoS96 Europe PMC51
2014 Taheri, S., Cavallaro, A., Christo, S., Smith, L., Majewski, P., Barton, M., . . . Vasilev, K. (2014). Substrate independent silver nanoparticle based antibacterial coatings. Biomaterials, 35(16), 4601-4609.
DOI Scopus145 WoS126 Europe PMC62
2014 Liu, L., Cooper, T., Howley, P., & Hayball, J. (2014). From crescent to mature virion: vaccinia virus assembly and maturation. Viruses, 6(10), 3787-3808.
DOI Scopus52 WoS43 Europe PMC43
2014 Simovic, S., Diener, K., Bachhuka, A., Kant, K., Losic, D., Hayball, J., . . . Vasilev, K. (2014). Controlled release and bioactivity of the monoclonal antibody rituximab from a porous matrix: a potential in situ therapeutic device. Materials Letters, 130, 210-214.
DOI Scopus11 WoS11
2013 Della Vedova, C., Cathcart, S., Dohnalek, A., Lee, V., Hutchinson, M., Immink, M., & Hayball, J. (2013). Peripheral interleukin-1β levels are elevated in chronic tension-type headache patients. Pain Research & Management : The Journal of the Canadian Pain Society = journal de la société canadienne pour le traitement de la douleur, 18(6), 301-306.
DOI Scopus37 WoS28 Europe PMC30
2013 Cathcart, S., Barone, V., Immink, M., Proeve, M., & Hayball, J. (2013). Mindfulness training does not reduce inflammatory cytokine levels in chronic tension-type headache. Journal of Pain Management, 6(3), 235-238.
Scopus4
2013 Nguyen, T., Arthur, A., Hayball, J., & Gronthos, S. (2013). Ephb and Ephrin-B interactions mediate human mesenchymal stem cell suppression of activated T-cells. Stem Cells and Development, 22(20), 2751-2764.
DOI Scopus64 WoS63 Europe PMC56
2013 Diener, K., Al-Dasooqi, N., Lousberg, E., & Hayball, J. (2013). The multifunctional alarmin HMGB1 with roles in the pathophysiology of sepsis and cancer. Immunology and Cell Biology, 91(7), 443-450.
DOI Scopus78 WoS76 Europe PMC71
2013 Stevens, N., Fraser, C., Alsharifi, M., Brown, M., Diener, K., & Hayball, J. (2013). An empirical approach towards the efficient and optimal production of influenza-neutralizing ovine polyclonal antibodies demonstrates that the novel adjuvant CoVaccine HT™ is functionally superior to Freund's adjuvant. PLoS One, 8(7), 1-10.
DOI Scopus11 WoS9 Europe PMC10
2013 Kaiko, G., Loh, Z., Spann, K., Lynch, J., Lalwani, A., Zheng, Z., . . . Phipps, S. (2013). Toll-like receptor 7 gene deficiency and early-life Pneumovirus infection interact to predispose toward the development of asthma-like pathology in mice. Journal of Allergy and Clinical Immunology, 131(5), 1331-1349.
DOI Scopus62 WoS60 Europe PMC54
2013 Locock, K. E. S., Michl, T. D., Valentin, J. D. P., Vasilev, K., Hayball, J. D., Qu, Y., . . . Haeussler, M. (2013). Guanylated polymethacrylates: a class of potent antimicrobial polymers with low hemolytic activity. Biomacromolecules, 14(11), 4021-4031.
DOI Scopus205 WoS193 Europe PMC112
2012 Cathcart, S., Bhullar, N., Immink, M. A., Della Vedova, C., & Hayball, J. D. (2012). Pain sensitivity mediates the relationship between stress and headache intensity in chronic tension-type headache. Pain Research and Management, 17(6), 377-380.
DOI Scopus23 WoS24 Europe PMC17
2012 Miller, D., Brown, M., Howley, P., & Hayball, J. (2012). Current and emerging immunotherapeutic approaches to treat and prevent peanut allergy. Expert Review of Vaccines, 11(12), 1471-1481.
DOI Scopus7 WoS7 Europe PMC5
2012 Coad, B., Scholz, T., Vasilev, K., Hayball, J., Short, R., & Griesser, H. (2012). Functionality of Proteins Bound to Plasma Polymer Surfaces. ACS Applied Materials and Interfaces, 4(5), 2455-2463.
DOI Scopus56 WoS55 Europe PMC21
2012 Wu, Y., Lousberg, E., Moldenhauer, L., Hayball, J., Coller, J., Rice, K., . . . Hutchinson, M. (2012). Inhibiting the TLR4-MyD88 signalling cascade by genetic or pharmacological strategies reduces acute alcohol-induced sedation and motor impairment in mice. British Journal of Pharmacology, 165(5), 1319-1329.
DOI Scopus69 WoS59 Europe PMC60
2012 Coad, B., Vasilev, K., Diener, K., Hayball, J., Short, R., & Griesser, H. (2012). Immobilized Streptavidin gradients as bioconjugation platforms. Langmuir, 28(5), 2710-2717.
DOI Scopus35 WoS35 Europe PMC19
2012 Christo, S., Sarvestani, G., Griesser, S., Coad, B., Griesser, H., Vasilev, K., . . . Hayball, J. (2012). Individual and population quantitative analyses of calcium flux in T-cells activated on functionalized material surfaces. Australian Journal of Chemistry, 65(1), 45-49.
DOI Scopus7 WoS7
2012 Diener, K., Christo, S., Griesser, S., Tahmasebi-Sarvestani, G., Vasilev, K., Griesser, H., & Hayball, J. (2012). Solid-state capture and real-time analysis of individual T cell activation via self-assembly of binding multimeric proteins on functionalized materials surfaces. Acta Biomaterialia, 8(1), 99-107.
DOI Scopus14 WoS14 Europe PMC9
2011 Lousberg, E., Diener, K., Brown, M., & Hayball, J. (2011). Innate immune recognition of poxviral vaccine vectors. Expert Review of Vaccines, 10(10), 1435-1449.
DOI Scopus16 WoS16 Europe PMC15
2011 Furuya, Y., Chan, J., Wan, E., Koskinen, A., Diener, K., Hayball, J., . . . Alsharifi, M. (2011). Gamma-irradiated influenza virus uniquely induces IFN-I mediated lymphocyte activation independent of the TLR7/MyD88 pathway. PLoS One, 6(10), e25765-1-e25765-12.
DOI Scopus18 WoS16 Europe PMC15
2011 Guerin, L., Moldenhauer, L., Prins, J., Bromfield, J., Hayball, J., & Robertson, S. (2011). Seminal fluid regulates accumulation of FOXP3(+) regulatory T cells in the preimplantation mouse uterus through expanding the FOXP3(+) cell pool and CCL19-mediated recruitment. Biology of Reproduction, 85(2), 397-408.
DOI Scopus194 WoS180 Europe PMC164
2011 Wu, Y., Lousberg, E., Moldenhauer, L., Hayball, J., Robertson, S., Coller, J., . . . Hutchinson, M. (2011). Attenuation of microglial and IL-1 signaling protects mice from acute alcohol-induced sedation and/or motor impairment. Brain Behavior and Immunity, 25(Suppl 1), 155-164.
DOI Scopus71 WoS54 Europe PMC61
2011 Moldenhauer, L. M., Keenihan, S. N., Hayball, J. D., & Robertson, S. A. (2011). GM-CSF regulates uterine dendritic cell and macrophage maturation and antigen presentation. Journal of reproductive immunology, 90(2), 134-135.
DOI WoS2
2011 Lousberg, E., Diener, K., Fraser, C., Phipps, S., Foster, P., Chen, W., . . . Hayball, J. (2011). Antigen-specific T-cell responses to a recombinant fowlpox virus are dependent on MyD88 and interleukin-18 and independent of toll-like receptor 7 (TLR7)- and TLR9-mediated innate immune recognition. Journal of Virology, 85(7), 3385-3396.
DOI Scopus12 WoS11 Europe PMC13
2010 Fraser, C., Lousberg, E., Guerin, L., Hughes, T., Brown, M., Diener, K., & Hayball, J. (2010). Dasatinib alters the metastatic phenotype of B16-OVA melanoma in vivo. Cancer Biology & Therapy, 10(7), 715-727.
DOI Scopus11 WoS11 Europe PMC9
2010 Fraser, C., Diener, K., Lousberg, E., Both, G., Ward, L., Brown, M., & Hayball, J. (2010). Induction of both cellular and humoral immunity following a rational prime-boost immunization regimen that incorporates recombinant ovine atadenovirus and fowlpox virus. Clinical and Vaccine Immunology, 17(11), 1679-1686.
DOI Scopus6 WoS5 Europe PMC4
2010 Moldenhauer, L., Keenihan, S., Hayball, J., & Robertson, S. (2010). GM-CSF is an essential regulator of T cell activation competence in uterine dendritic cells during early pregnancy in mice. Journal of Immunology, 185(11), 7085-7096.
DOI Scopus89 WoS85 Europe PMC73
2010 Moldenhauer, L., Hayball, J., & Robertson, S. (2010). Utilising T cell receptor transgenic mice to define mechanisms of maternal T cell tolerance in pregnancy. Journal of Reproductive Immunology, 87(1-2), 1-13.
DOI Scopus42 WoS39 Europe PMC34
2010 Fraser, C., Brown, M., Diener, K., & Hayball, J. (2010). Unravelling the complexity of cancer-immune system interplay. Expert Review of Anticancer Therapy, 10(6), 917-934.
DOI Scopus5 WoS5 Europe PMC3
2010 Diener, K., Need, E., Buchanan, G., & Hayball, J. (2010). TGF-β signalling and immunity in prostate tumourigenesis. Expert Opinion On Therapeutic Targets, 14(2), 179-192.
DOI Scopus20 WoS21 Europe PMC17
2010 Lousberg, E., Fraser, C., Tovey, M., Diener, K., & Hayball, J. (2010). Type I interferons mediate the innate cytokine response to recombinant fowlpox virus but not the induction of plasmacytoid dendritic cell-dependent adaptive immunity. Journal of Virology, 84(13), 6549-6563.
DOI Scopus21 WoS20 Europe PMC20
2010 Moldenhauer, L. M., Hudson-Keenihan, S. N., Hayball, J. D., & Robertson, S. A. (2010). GM-CSF regulates uterine macrophage and dendritic cell maturation and antigen presentation. JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 86(1), 31-32.
DOI
2009 Fraser, C., Lousberg, E., Kumar, R., Hughes, T., Diener, K., & Hayball, J. (2009). Dasatinib inhibits the secretion of TNF-α following TLR stimulation in vitro and in vivo. Experimental Hematology, 37(12), 1435-1444.
DOI Scopus38 WoS38 Europe PMC34
2009 Robertson, S., Guerin, L., Moldenhauer, L., & Hayball, J. (2009). Activating T regulatory cells for tolerance in early pregnancy - the contribution of seminal fluid. Journal of Reproductive Immunology, 83(1-2), 109-116.
DOI Scopus157 WoS141 Europe PMC120
2009 Moldenhauer, L., Diener, K., Thring, D., Brown, M., Hayball, J., & Robertson, S. (2009). Cross-presentation of male seminal fluid antigens elicits T cell activation to initiate the female immune response to pregnancy. Journal of Immunology, 182(12), 8080-8093.
DOI Scopus221 WoS205 Europe PMC190
2009 Diener, K., Woods, A., Manavis, J., Brown, M., & Hayball, J. (2009). Transforming growth factor-β-mediated signaling in T lymphocytes impacts on prostate-specific immunity and early prostate tumor progression. Laboratory Investigation, 89(2), 142-151.
DOI Scopus14 WoS14 Europe PMC13
2009 Fraser, C., Blake, S., Diener, K., Lyons, A., Brown, M., Hughes, T., & Hayball, J. (2009). Dasatinib inhibits recombinant viral antigen-specific murine CD4+ and CD8+ T-cell responses and NK-cell cytolytic activity in vitro and in vivo. Experimental Hematology, 37(2), 256-265.
DOI Scopus58 WoS56 Europe PMC51
2008 Diener, K., Lousberg, E., Beukema, E., Yu, A., Howley, P., Brown, M., & Hayball, J. (2008). Recombinant fowlpox virus elicits transient cytotoxic T cell responses due to suboptimal innate recognition and recruitment of T cell help. Vaccine, 26(29-30), 3566-3573.
DOI Scopus10 WoS7 Europe PMC7
2008 Blake, S., Lyons, A., Fraser, C., Hayball, J., & Hughes, T. (2008). Dasatinib suppresses in vitro natural killer cell cytotoxicity. Blood, 111(8), 4415-4416.
DOI Scopus69 WoS69 Europe PMC62
2008 Diener, K., Moldenhauer, L., Lyons, A., Brown, M., & Hayball, J. (2008). Human Flt-3 ligand-mobilized dendritic cells, require additional activation to drive effective immune responses. Experimental Hematology, 36(1), 51-60.
DOI Scopus18 WoS18 Europe PMC16
2008 Wong, M., Hayball, J., & Jackson, D. (2008). PECAM-1-regulated signalling thresholds control tolerance in anergic transgenic B-Cells. Molecular Immunology, 45(6), 1767-1781.
DOI Scopus3 WoS3 Europe PMC3
2008 Robertson, S. A., Moldenhauer, L. M., & Hayball, J. D. (2008). GMCSF is an essential regulator of uterine dendritic cells in early pregnancy. Biology of reproduction, 78(Suppl_1), 197.
DOI WoS3
2007 Robertson, S. A., Moldenhauer, L., Hudson-Keenihan, S. N., & Hayball, J. D. (2007). GM-CSF is an essential regulator of uterine dendritic cells in early pregnancy. PLACENTA, 28(8-9), A31.
2007 Fraser, C., Diener, K., Brown, M., & Hayball, J. (2007). Improving vaccines by incorporating immunological coadjuvants. Expert Review of Vaccines, 6(4), 559-578.
DOI Scopus80 WoS68 Europe PMC54
2007 Al-ejeh, F., Darby, J., Pensa, K., Diener, K., Hayball, J., & Boucaut, R. (2007). In vivo targeting of dead tumor cells in a Murine Tumor Model using a monoclonal antibody specific for the La Autoantigen. Clinical Cancer Research, 13(18), 5519-5527.
DOI Scopus33 WoS27 Europe PMC26
2007 Fraser, C. K., Diener, K. R., Brown, M. P., & Hayball, J. D. (2007). Erratum: Improving vaccines by incorporating immunological coadjuvants (Expert Review Vaccines (2007) 6, 4, (559-578)). Expert Review of Vaccines, 6(6), 1022.
DOI
2007 Fraser, C. K., Diener, K. R., Brown, M. P., & Hayball, J. D. (2007). Improving vaccines by incorporating immunological coadjuvants (vol 6, pg 559, 2007). EXPERT REVIEW OF VACCINES, 6(6), 1022.
2007 Ramalingam, S. S., Parise, R. A., & Ramanathan, R. K. (2007). Clinical cancer research (vol 13, pg 3605, 2007). CLINICAL CANCER RESEARCH, 13(20), 6245.
DOI WoS1
2006 Beukema, E., Brown, M., & Hayball, J. (2006). The potential role of fowlpox virus in rational vaccine design. Expert Review of Vaccines, 5(4), 565-577.
DOI Scopus24 WoS21 Europe PMC18
2006 Lees, J., Charbonneau, B., Hayball, J., Diener, K., Brown, M., Matusik, R., . . . Ratliff, T. (2006). T-cell recognition of a prostate specific antigen is not sufficient to induce prostate tissue destruction. Prostate, 66(6), 578-590.
DOI Scopus26 WoS25 Europe PMC25
2005 Morrison, R., Lyons, A., Nowak, B., & Hayball, J. (2005). Assessment of snapper (Pagrus auratus) natural IgM binding to bromelain treated sheep erythrocytes. Fish & Shellfish Immunology, 18(1), 91-99.
DOI Scopus4 WoS4 Europe PMC4
2005 Cook, M., Hayball, P., Nowak, B., & Hayball, J. (2005). The opsonising activity of a pentraxin-like protein isolated from snapper (Pagrus auratus, Sparidae) serum. Developmental and Comparative Immunology, 29(8), 703-712.
DOI Scopus25 WoS19 Europe PMC16
2005 Hayball, J., & Lake, R. (2005). The immune function of MHC class II molecules mutated in the putative superdimer interface. Molecular and Cellular Biochemistry, 273(1-2), 1-9.
DOI Scopus8 WoS7 Europe PMC7
2005 Wong, M., Hayball, J., Hogarth, P., & Jackson, D. (2005). The inhibitory co-receptor, PECAM-1 provides a protective effect in suppression of collagen-induced arthritis. Journal of Clinical Immunology, 25(1), 19-28.
DOI Scopus43 WoS44 Europe PMC41
2005 Moldenhauer, L. M., Hayball, J. D., & Robertson, S. A. (2005). Conceptus antigens act to systemically prime the maternal immune system in pregnancy. TISSUE ANTIGENS, 66(5), 495-496.
2004 Morrison, R., Lyons, A., Nowak, B., & Hayball, J. (2004). Snapper (Pagrus auratus) leucocyte proliferation is synergistically enhanced by simultaneous stimulation with LPS and PHA. Fish & Shellfish Immunology, 16(3), 307-319.
DOI Scopus17 WoS13 Europe PMC11
2004 Hayball, J. D., Lake, R., & Robinson, B. (2004). CD4(+) T cells cross-compete for MHC class II-restricted peptide antigen complexes on the surface of antigen presenting cells. Immunology and cell biology, 82(2), 103-111.
DOI Scopus18 WoS18 Europe PMC18
2003 Cook, M., Hayball, P. J., Hutchinson, W., Nowak, B. F., & Hayball, J. D. (2003). Administration of commercial immunostimulant preparation, EcoActiva as a feed supplement enhances macrophage respiratory burst and the growth rate of snapper (Pagrus auratus, Sparidae (Bloch and Schneider)) in winter. Fish and Shellfish Immunology, 14(4), 333-345.
DOI Scopus139 WoS126 Europe PMC77
2003 Cook, M., Hayball, P., Birdseye, L., Bagley, C., Nowak, B., & Hayball, J. (2003). Isolation and partial characterization of a pentraxin-like protein with complement-fixing activity from snapper (Pagrus auratus, Sparidae) serum. Developmental and Comparative Immunology, 27(6-7), 579-588.
DOI Scopus33 WoS30 Europe PMC16
2002 Croker, B., Handman, E., Hayball, J., Baldwin, T., Voigt, V., Cluse, L., . . . Roberts, A. (2002). Rac2-deficient mice display perturbed T-cell distribution and chemotaxis, but only minor abnormalities in TH1 responses. Immunology and Cell Biology, 80(3), 231-240.
DOI Scopus56 WoS50 Europe PMC46
2002 Morrison, R., Hayball, J., Cook, M., & Nowak, B. (2002). Anti-immunoglobulin binding and activation of snapper (Pagrus auratus) leucocytes. Developmental and Comparative Immunology, 26(3), 247-255.
DOI Scopus9 WoS9 Europe PMC4
2001 Cook, M. T., Hayball, P. J., Hutchinson, W., Nowak, B., & Hayball, J. D. (2001). The efficacy of a commercial beta-glucan preparation, EcoActiva(TM), on stimulating respiratory burst activity of head-kidney macrophages from pink snapper (Pagrus auratus), Sparidae. Fish and shellfish immunology, 11(8), 661-672.
DOI Scopus68 WoS62 Europe PMC43
2001 Cook, M. T., Morrison, R., Hayball, J. D., Nowak, B., Hayball, P. J., & Wilkinson, R. (2001). A screen of mammalian antibodies on snapper (Pagrus auratus, Sparidae) peripheral blood leukocytes reveals cross reactivity of an anti-human CD3 antibody with a population of mIg(-) cells. Developmental and Comparative Immunology, 25(7), 553-559.
DOI Scopus20 WoS19 Europe PMC18
2000 Hayball, J. D., & Lake, R. A. (2000). Altered superantigenic ligands demonstrate the quantitative nature of T-cell activation. Immunology and Cell Biology, 78(6), 623-632.
DOI Scopus1 WoS1 Europe PMC1
2000 Hayball, J. D., & Lake, R. A. (2000). Partial T cell activation with an altered superantigenic ligand. Immunology and Cell Biology, 78(1), 13-19.
DOI Scopus4 WoS4 Europe PMC4
1999 Lake, R. A., Robinson, B. W. S., & Hayball, J. D. (1999). MHC multimerization, antigen expression and the induction of APC amnesia in the developing immune response. Immunology and Cell Biology, 77(1), 99-104.
DOI Scopus9 WoS8 Europe PMC5
1997 Hayball, J. D., Fidler, S. J., Palliser, D., Rees, A. D. M., Lamb, J. R., & Lake, R. A. (1997). Tandem peptide epitopes facilitate CD4-dependent activation of T cell clones. Immunology and Cell Biology, 75(2), 148-153.
DOI Scopus6 WoS6 Europe PMC5
1996 Hayball, J., Jones, C., Lamb, J., & Lake, R. (1996). A T cell clone with three potential TCR alpha chain rearrangements expresses only one receptor combination at the cell surface. Molecular Immunology, 33(15), 1177-1181.
DOI Scopus3 WoS3 Europe PMC3
1996 Kristensen, N., Hoyne, G., Hayball, J., Hetzel, C., Bourne, T., & Lamb, J. (1996). Induction of T cell responses to the invariant chain derived peptide CLIP in mice immunized with the group 1 allergen of house dust mite. International Immunology, 8(7), 1091-1098.
DOI Scopus10 WoS10 Europe PMC9
1995 Lamb, J. R., Higgins, J. A., Hetzel, C., Hayball, J. D., Lake, R. A., & O'Hehir, R. E. (1995). The effects of changes at peptide residues contacting MHC class II T-cell receptor on antigen recognition and human Th0 cell effector function. Immunology, 85(3), 447-454.
Scopus20 WoS16 Europe PMC9
1995 Hayball, J. D., O’Hehir, R. E., Lamb, J. R., & Lake, R. A. (1995). The Domain Structure and Functional Relationships in the Bacterial Superantigen, SEB. Biological Chemistry Hoppe Seyler, 376(5), 303-310.
DOI Scopus4 WoS4 Europe PMC3
1994 Hayball, J. D., Robinson, J. H., O'hehlr, R. E., Verhoef, A., Lamb, J. R., & Lake, R. A. (1994). Identification of two binding sites in staphylococcal enterotoxin B that confer specificity for TCR Vβ gene products. International Immunology, 6(2), 199-211.
DOI Scopus25 WoS25 Europe PMC16
1994 Higgins, J. A., Thorpe, C. J., Hayball, J. D., O'Hehir, R. E., & Lamb, J. R. (1994). Overlapping T-cell epitopes in the group I allergen of Dermatophagoides species restricted by HLA-DP and HLA-DR class II molecules. Journal of Allergy and Clinical Immunology, 93(5), 891-899.
DOI Scopus82 WoS84 Europe PMC60
1993 OHEHIR, R. E., VERHOEF, A., PANAGIOTOPOULOU, E., KESWANI, S., HAYBALL, J. D., THOMAS, W. R., & LAMB, J. R. (1993). ANALYSIS OF HUMAN T-CELL RESPONSES TO THE GROUP-II ALLERGEN OF DERMATOPHAGOIDES SPECIES - LOCALIZATION OF MAJOR ANTIGENIC SITES. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 92(1), 105-113.
DOI WoS90 Europe PMC65
1993 Verhoef, A., Higgins, J. A., Thorpe, C. J., Marsh, S. G. E., Hayball, J. D., Lamb, J. R., & O'hehir, R. E. (1993). Clonal analysis of the atopic immune response to the group 2 allergen of dermatophagoides spp.: Identification of HLA-DR and -DQ restricted T cell epitopes. International Immunology, 5(12), 1589-1597.
DOI Scopus79 WoS76 Europe PMC53
1993 O'Hehir, R. E., Verhoef, A., Panagiotopoulou, E., Keswani, S., Hayball, J. D., Thomas, W. R., & Lamb, J. R. (1993). Analysis of human T cell responses to the group II allergen of Dermatophagoides species: Localization of major antigenic sites. Journal of Allergy and Clinical Immunology, 92(1 PART I), 105-113.
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1993 Fujiwara, H., Kurihara, N., Hirata, K., Ohta, K., Kanazawa, H., & Takeda, T. (1993). Effect of neuropeptide Y on human bronchus and its modulation of neutral endopeptidase. The Journal of Allergy and Clinical Immunology, 92(1 PART 1), 89-94.
DOI Scopus1
1992 Hewitt, C. R. A., Lamb, J. R., Hayball, J., Hill, M., Owen, M. J., & O'Hehir, R. E. (1992). Major histocompatibility complex independent clonal T cell anergy by direct interaction of Staphylococcus aureus enterotoxin B with the T cell antigen receptor. Journal of Experimental Medicine, 175(6), 1493-1499.
DOI Scopus152 WoS145 Europe PMC108
1992 Higgins, J. A., Lamb, J. R., Marsh, S. G. E., Tonks, S., Hayball, J. D., Rosen-Bronson, S., . . . O'Hehir, R. E. (1992). Peptide-induced nonresponsiveness of HLA-DP restricted human T cells reactive with Dermatophagoides spp. (house dust mite). Journal of Allergy and Clinical Immunology, 90(5), 749-756.
DOI Scopus80 WoS91 Europe PMC48
1991 Busch, R., Hill, C. M., Hayball, J. D., Lamb, J. R., & Rothbard, J. B. (1991). Effect of natural polymorphism at residue 86 of the HLA-DR β chain on peptide binding. Journal of Immunology, 147(4), 1292-1298.
DOI Scopus116 WoS112 Europe PMC70
1991 Hill, C. M., Hayball, J. D., Allison, A. A., & Rothbard, J. B. (1991). Conformational and structural characteristics of peptides binding to HLA-DR molecules. Journal of Immunology, 147(1), 189-197.
DOI Scopus75 WoS79 Europe PMC44

Year Citation
2014 Howley, P. M., Diener, K. R., & Hayball, J. D. (2014). Making an avipoxvirus encoding a tumor-associated antigen and a costimulatory molecule. In M. J. P. Lawman, & P. Lawman (Eds.), Source details - Title: Cancer Vaccines: Methods and Protocols, Methods in Molecular Biology (Vol. 1139, pp. 407-427). US: Springer.
DOI Scopus1 Europe PMC1
2013 Cathcart, S., Vedova, C. D., Immink, M., Proeve, M., & Hayball, J. (2013). Mindfulness training and inflammatory cytokine levels in chronic tension-type headache. In Disability and Chronic Disease (pp. 153-158).

Year Citation
2020 Valtanen, P. G., Zhang, J., Scammell, A., Parkinson-Lawrence, E., Michael, M., Hussey, D., . . . Hayball, J. (2020). New polyclonal antibody therapeutic to treat esophageal adenocarcinoma and Barrett's esophagus by targeting EPHB4. In ANNALS OF ONCOLOGY Vol. 31 (pp. S167). ELECTR NETWORK: ELSEVIER.
DOI
2018 Li, W., Qu, R., Chen, X., Wang, W., Hayball, J., Vasilev, K., & Zhao, Y. (2018). Cortistatin Directly Binds to RANK and Protects Against Osteoporosis in Mice. In JOURNAL OF BONE AND MINERAL RESEARCH Vol. 33 (pp. 96). CANADA, Montreal: WILEY.
2018 Genuino, R. M. G., Eldi, P., Garcia-Valtanen, P., Hayball, J. D., & Diener, K. R. (2018). Lymphatic and uterine B cells contribute to maternal immunological tolerance during murine pregnancy. In JOURNAL OF IMMUNOLOGY Vol. 200 (pp. 3 pages). Austin, TX: AMER ASSOC IMMUNOLOGISTS.
2018 Day, J., Otto, S., Cash, K., Eldi, P., Hissaria, P., Proudman, S., . . . Limaye, V. (2018). Aberrant Sarcoplasmic Expression of the Alarmin 'High Mobility Group Box Protein 1" (HMGB1) in Patients with Idiopathic Inflammatory Myopathy. In ARTHRITIS & RHEUMATOLOGY Vol. 70 (pp. 2 pages). IL, Chicago: WILEY.
2017 Eldi, P., Cooper, T., Liu, L., Howley, P., Smith, W., & Hayball, J. (2017). A NOVEL IMMUNOTHERAPEUTIC VACCINE TO MODULATE CYTOKINE RESPONSES OF ANTIGEN-SPECIFIC CD4<SUP>+</SUP> T CELLS IN PEANUT ALLERGY. In INTERNAL MEDICINE JOURNAL Vol. 47 (pp. 14). WILEY.
DOI
2016 Eldi, P., Chataway, T., Tao, B., Smith, W., & Hayball, J. (2016). BIOMARKERS FOR IDENTIFICATION OF PEANUT ALLERGEN-SPECIFIC T CELLS. In INTERNAL MEDICINE JOURNAL Vol. 46 (pp. 7). WILEY-BLACKWELL.
DOI
2016 Hayball, J., Liu, L., Cooper, T., Eldi, P., & Howley, P. (2016). SCV platform: a novel replication-incompetent vaccinia viral vaccine vector system. In EUROPEAN JOURNAL OF IMMUNOLOGY Vol. 46 (pp. 1227). AUSTRALIA, Melbourne: WILEY-BLACKWELL.
2016 Hayball, J., Cooper, T., Liu, L., Eldi, P., Tan, M., Prow, N., . . . Howley, P. (2016). A dual Chikungunya and smallpox vaccine derived from a novel, replication-incompetent poxvirus vaccine system provides mice with complete protection from Chikungunya virus and mousepox infection. In EUROPEAN JOURNAL OF IMMUNOLOGY Vol. 46 (pp. 809). AUSTRALIA, Melbourne: WILEY-BLACKWELL.
2016 Visalakshan, R. M., Cavallaro, A., Smith, L. E., MacGregor Ramiasa, M., Hayball, J., & Vasilev, K. (2016). Downstream influences of oxazoline plasma polymerisation conditions on chemical and biological interactions. In Chemeca 2016: Chemical engineering - regeneration, recovery and reinvention (pp. 840-848). Australia: Engineers Australia.
2016 Lynch, J. P., Werder, R. B., Loh, Z., Lane, K., Rogers, M., Diener, K., . . . Phipps, S. (2016). Uncoupling of the pDC-Treg crosstalk during early-life Pneumovirus infection underlies long-lived Treg dysfunction and asthma development. In EUROPEAN JOURNAL OF IMMUNOLOGY Vol. 46 (pp. 471). Melbourne, AUSTRALIA: WILEY-BLACKWELL.
2015 Lynch, J., Rogers, M., Lane, K., Werder, R., Loh, Z., Diener, K., . . . Phipps, S. (2015). PDC EXPANSION OF NTREG LIMITS SEVERE PNEUMOVIRUS-INDUCED BRONCHIOLITIS AND ATTENUATES THE ONSET OF VIRUS-PROVOKED ASTHMA. In RESPIROLOGY Vol. 20 (pp. 141). Queensland, AUSTRALIA: WILEY-BLACKWELL.
2014 Lynch, J. P., Werder, R. B., Rogers, M. J., Lane, K., Loh, Z., Simpson, J., . . . Phipps, S. (2014). pDC expansion of nTreg limits severe Pneumovirus-induced bronchiolitis and attenuates the onset of virus-provoked asthma. In IMMUNOLOGY Vol. 143 (pp. 124). WILEY-BLACKWELL.
2005 Beukema, E., Brown, M. P., Howley, P. M., & Hayball, J. D. (2005). Developing approaches to the immunological analysis of vector dominant immune responses using recombinant fowlpox virus vectors (RFPV). In TISSUE ANTIGENS Vol. 66 (pp. 362). Melbourne, AUSTRALIA: BLACKWELL PUBLISHING.
2005 Wong, M., Hayball, J. D., Hogarth, M. P., & Jackson, D. E. (2005). Defective thymocyte selection in PECAM-1 deficient mice. In TISSUE ANTIGENS Vol. 66 (pp. 592). Melbourne, AUSTRALIA: BLACKWELL PUBLISHING.
2005 Jackson, D. E., Hayball, J. D., Goodnow, C. C., Hogarth, M. P., & Wong, M. X. (2005). PECAM-1-mediated signalling is important in regulation of tolerance and autoimmunity. In TISSUE ANTIGENS Vol. 66 (pp. 452). Melbourne, AUSTRALIA: WILEY-BLACKWELL PUBLISHING, INC.
1993 HAYBALL, J. D., LAMB, J. R., & LAKE, R. A. (1993). IDENTIFICATION OF BINDING-SITES IN STAPHYLOCOCCAL ENTEROTOXIN-B THAT CONFER SPECIFICITY FOR T-CELL RECEPTOR V-BETA-GENE PRODUCTS. In JOURNAL OF LEUKOCYTE BIOLOGY (pp. 56). FEDERATION AMER SOC EXP BIOL.

Year Citation
2013 Thao, N., Gronthos, S., Arthur, A., & Hayball, J. (2013). Ephb and Ephrin-B interactions mediate human mesenchymal stem cell suppression of activated T-cells. Poster session presented at the meeting of Abstracts of the Ephb and Ephrin-B interactions mediate human mesenchymal stem cell suppression of activated T-cells, as published in Experimental Hematology. Vienna, AUSTRIA: Elsevier.
DOI
2010 Guerin, L. R., Moldenhauer, L. M., Prins, J., Bromfield, J. D. J., Hayball, J. D., & Robertson, S. A. (2010). Seminal fluid regulates the uterine Foxp3<SUP>+</SUP> T regulatory cell population through CCL19-mediated recruitment during the pen-implantation period in mice. Poster session presented at the meeting of JOURNAL OF REPRODUCTIVE IMMUNOLOGY. Palm Cove, AUSTRALIA: ELSEVIER IRELAND LTD.
DOI
2009 Moldenhauer, L. M., Hayball, J. D., & Robertson, S. A. (2009). Immune-deviating cytokines determine the maternal T cell response and conceptus tolerance or rejection. Poster session presented at the meeting of Abstracts of the 42nd Annual Meeting of the Society for the Study of Reproduction, as published in Biology of Reproduction. Pittsburgh, PA: Society for the Study of Reproduction.
WoS2
2006 Moldenhauer, L. M., Hayball, J. D., & Robertson, S. A. (2006). Conceptus antigens activate the maternal immune response in pregnancy utilising maternal antigen presenting cells. Poster session presented at the meeting of Abstracts of the 3rd International Conference on Experimental and Clinical Reproductive Immunobiology, as published in Journal of Reproductive Immunology. Banff, Canada: Elsevier.
DOI WoS2

Year Citation
2021 Prow, N., Howley, P., Cooper, T., Hayball, J., Diener, K. R., Liu, L., & Eldi, P. (2021). US20210299245A1, Attenuated poxvirus vector based vaccine for protection against covid-19.
2018 Chalker, J., Hayball, J., Plush, S., & Sweetman, M. J. (2018). AU2018902544, Sorbent compositions.
2014 Hayball, J. D., Diener, K. R., Christo, S., Nordon, R., & Christo, F. C. (2014). WO2015017889, Analysing intracellular calcium flux in cells including T cells.

  • Immunisation to protect against transmissible cancers in Tasmanian devils, ARC - Discovery Projects, 01/01/2018 - 31/12/2021

  • 'Intelligent' antibacterial coatings for improving outcomes with infections associated with dialysis catheters, NHMRC - Project Grant, 01/01/2017 - 31/12/2021

  • Sementis Stage 4 Vaccine Development Research, Sementis Pty Ltd, 15/03/2018 - 01/10/2021

  • A solid dose vaccine delivery system for SCV, Sementis Pty Ltd, 01/12/2020 - 30/06/2021

  • Sementis SCV Vaccine Development Research Support, Sementis Pty Ltd, 01/01/2019 - 01/02/2021

  • Surface engineered biomaterials to control inflammation, ARC - Discovery Projects, 29/01/2015 - 31/12/2020

  • Development and production of advanced carbon water purification materials, Puratap Pty Ltd, 09/12/2017 - 09/12/2020

  • Development and production of advanced carbon water purification materials, SIEF STEM+ Business Fellowship Program, 09/12/2017 - 09/12/2020

  • SCV vector vaccine manufacturing optimization, Sementis Pty Ltd, 08/11/2017 - 07/11/2020

  • SCV vector vaccine manufacturing optimization, SIEF STEM+ Business Fellowship Program, 08/11/2017 - 07/11/2020

  • To develop a method or procedure to reduce environmental impact related to the destruction of PFAS contaminated filters, Cwth Dept Industry, Science, Energy & Resources, 02/09/2019 - 30/09/2020

  • To develop a method or procedure to reduce environmental impact related to the destruction of PFAS contaminated filters, Membrane Systems Australia, 02/09/2019 - 30/09/2020

  • CRC-P Industrialisation of a Novel Diagnostic Biosensor for Bladder Cancer, SMR Automotive Australia Pty Ltd, 01/04/2017 - 30/06/2020

  • Enhanced mulivalent vaccine responses using a novel vaccine vector system, Sementis Pty Ltd, 15/08/2016 - 30/04/2020

  • Characterising the subtypes of idiopathic inflammatory myopathies (IIMs) in terms of immumopathogenesis, neuroimaging and response to immunotherapy, Central Adelaide Local Health Network Incorporated, 02/01/2017 - 31/12/2019

  • Development of a prototype immunomodulatory vaccine for cat allergy, Sementis Pty Ltd, 02/09/2016 - 19/12/2019

  • Development of a prototype immunomodulatory vaccine for cat allergy, SIEF STEM+ Business Fellowship Program, 02/09/2016 - 02/09/2019

  • Enhanced mulivalent vaccine responses using a novel vaccine vector system (Industry Partner), Sementis Pty Ltd, 23/08/2016 - 31/08/2019

  • Enhanced multivalent vaccine responses using a novel vaccine vector system, ARC - Linkage Project, 23/08/2016 - 22/08/2019

  • HMGB1: a novel player in the pathogenesis of inflammatory myositis?, NHMRC - Postgraduate Research Scholarship, 18/02/2016 - 30/06/2019

  • Innate immunity, MRI and Rituximab projects funding assistance, Myositis Association Australia, 06/03/2017 - 31/03/2018

  • Process development for SCV vector vaccine production/manufacturing, Sementis Pty Ltd, 21/11/2016 - 29/12/2017

  • Process development for SCV vector vaccine production/manufacturing, DISER-Innovation Connections Grant, 21/11/2016 - 28/12/2017

  • Optimisation and testing of prototype (C'Wealth funding), Cwth Dept Industry, Science, Energy & Resources, 15/05/2017 - 08/12/2017

  • Translating human cancer immunotherapy for use in pets and Tasmanian devils, University of Tasmania, 01/08/2016 - 30/11/2017

  • Innovation connections puratap development of a chemical detection device, Puratap Pty Ltd, 01/04/2016 - 30/09/2017

  • Anti-inflammatory/bacterial effects of kinos from Australian and PNG eucalypts, The Royal Society, 02/05/2016 - 02/05/2017

  • Development of a chemical detection device, DISER-Innovation Connections Grant, 18/04/2016 - 18/04/2017

Date Role Research Topic Program Degree Type Student Load Student Name
2014 - 2021 Co-Supervisor HMGB1- An Immunotherapeutic Target for the Treatment of Neonatal Sepsis and Associated Neuroinflammation Doctor of Philosophy Doctorate Part Time Nerissa Lakhan
2008 - 2009 Principal Supervisor Characterising the Relationship between Fowlpox Virus and the Mammalian Immune System Master of Medical Science Master Full Time Mrs Emma Beukema
2008 - 2010 Co-Supervisor Seminal Fluid and Cytokine Control of Regulatory T-Cells in Murine Pregnancy Doctor of Philosophy Doctorate Full Time Mr Leigh Guerin
2006 - 2008 External Supervisor Pathways of Paternal Antigen Presentation to Initiate Antigen-Specific Immune Responses in Pregnancy Doctor of Philosophy Doctorate Full Time Dr Lachlan Moldenhauer
  • Position: Professor
  • Email: john.hayball@adelaide.edu.au
  • Alternative Contact: A/Prof&nbsp;Kerrilyn Diener Experimental Therapeutics Laboratory Deputy Head kerrilyn.diener@unisa.edu.au 0422 911549 Dr Tamara Cooper Experimental Therapeutics Laboratory Manager tamara.cooper@unisa.edu.au 8302 1139

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