João Aguiar Macedo Teixeira

Dr João Aguiar Macedo Teixeira

ARC Research Associate

School of Biological Sciences

Faculty of Sciences

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.


I am a population geneticist focusing on the evolution of humans and closely related species. I work across a wide range of topics at the forefront of modern human evolutionary genetics, including demographic inference, comparative genomics and natural selection.

Currently, my main research focus revolves around human evolution during the Pleistocene, in particular the admixture events between so-called modern and archaic humans after the out-of-Africa and before human colonisation of Sahul.

I am expert on uncovering signatures of natural selection in the genome, in particular balancing selection, and continue to study how advantageous genetic diversity can be maintained for millions of years in natural populations.

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  • Journals

    Year Citation
    2021 Teixeira, J. C., & Huber, C. D. (2021). The inflated significance of neutral genetic diversity in conservation genetics.. Proceedings of the National Academy of Sciences of the United States of America, 118(10), e2015096118.
    DOI
    2020 Teixeira, J., Jacobs, G., Stringer, C., Tuke, J., Hudjashov, G., Purnomo, G., . . . Helgen, K. (2020). Introgression, hominin dispersal and megafaunal survival in Late Pleistocene Island Southeast Asia.
    DOI
    2020 Souilmi, Y., Tobler, R., Johar, A., Williams, M., Grey, S., Schmidt, J., . . . Cooper, A. (2020). Ancient human genomes reveal a hidden history of strong selection in Eurasia.
    DOI
    2020 Roca-Rada, X., Souilmi, Y., Teixeira, J. C., & Llamas, B. (2020). Ancient DNA studies in pre-Columbian Mesoamerica. Genes, 11(11), 1-19.
    DOI
    2020 Williams, M., & Teixeira, J. (2020). A genetic perspective on human origins. Biochemist, 42(1), 6-10.
    DOI Scopus1
    2020 O'Neill, M. B., Laval, G., Aguiar Macedo Teixeira, J., Palmenberg, A. C., & Pepperell, C. S. (2020). Genetic susceptibility to severe childhood asthma and rhinovirus-C maintained by balancing selection in humans for 150 000 years. Human molecular genetics, 29(5), 736-744.
    DOI
    2020 Barquera, R., Collen, E., Di, D., Buhler, S., Aguiar Macedo Teixeira, J., Llamas, B., . . . Sanchez-Mazas, A. (2020). Binding affinities of 438 HLA proteins to complete proteomes of seven pandemic viruses and distributions of strongest and weakest HLA peptide binders in populations worldwide. HLA, 96(3), 277-298.
    DOI Scopus10 WoS7 Europe PMC7
    2019 Teixeira, J. C., & Cooper, A. (2019). Using hominin introgression to trace modern human dispersals. Proceedings of the National Academy of Sciences, 116(31), 15327-15332.
    DOI Scopus4 WoS4
    2018 Bitarello, B. D., de Filippo, C., Teixeira, J. C., Schmidt, J. M., Kleinert, P., Meyer, D., & Andrés, A. M. (2018). Signatures of Long-Term Balancing Selection in Human Genomes. Genome Biology and Evolution, 10(3), 939-955.
    DOI Scopus24 WoS25 Europe PMC14
    2015 Nogueiro, I., Teixeira, J., Amorim, A., Gusmão, L., & Alvarez, L. (2015). Reply to letter from Felice L. Bedford and Doron Yacobi. European Journal of Human Genetics, 23(8), 994-995.
    DOI
    2015 Nogueiro, I., Teixeira, J. C., Amorim, A., Gusmão, L., & Alvarez, L. (2015). Portuguese crypto-Jews: the genetic heritage of a complex history. Frontiers in Genetics, 6(FEB), 1-12.
    DOI Scopus6 WoS6 Europe PMC2
    2015 Teixeira, J. C., de Filippo, C., Weihmann, A., Meneu, J. R., Racimo, F., Dannemann, M., . . . Andrés, A. M. (2015). Long-Term Balancing Selection in LAD1 Maintains a Missense Trans-Species Polymorphism in Humans, Chimpanzees, and Bonobos. Molecular Biology and Evolution, 32(5), 1186-1196.
    DOI Scopus32 WoS30 Europe PMC20
    2015 Nogueiro, I., Teixeira, J., Amorim, A., Gusmão, L., & Alvarez, L. (2015). Echoes from Sepharad: signatures on the maternal gene pool of crypto-Jewish descendants. European Journal of Human Genetics, 23(5), 693-699.
    DOI Scopus8 WoS10 Europe PMC3
    2014 Key, F. M., Teixeira, J. C., de Filippo, C., & Andrés, A. M. (2014). Advantageous diversity maintained by balancing selection in humans. Current Opinion in Genetics & Development, 29, 45-51.
    DOI Scopus50 WoS50 Europe PMC33
    2011 Teixeira, J. C., Nogueiro, I., Goios, A., Gusmão, L., Amorim, A., & Alvarez, L. (2011). Mitochondrial DNA-control region sequence variation in the NE Portuguese Jewish community. Forensic Science International: Genetics Supplement Series, 3(1), e51-e52.
    DOI Scopus5
    Teixeira, J. C., & Huber, C. D. (n.d.). Dismantling a dogma: the inflated significance of neutral genetic
    diversity in conservation genetics.
  • Conference Papers

    Year Citation
    2020 Teixeira, J. C. (2020). Hominin introgression in Island Southeast Asia and Sahul. In AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY Vol. 171 (pp. 281). Los Angeles, CA: WILEY.
    2016 Andres, A. M., Dannemann, M., Teixeira, J., & Kelso, J. (2016). Balancing selection and adaptive introgression as sources of advantageous genetic diversity in populations. In AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY Vol. 159 (pp. 80-81). Atlanta, GA: WILEY-BLACKWELL.
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  • Current Higher Degree by Research Supervision (University of Adelaide)

    Date Role Research Topic Program Degree Type Student Load Student Name
    2020 Co-Supervisor Studying the impact of Old World diseases on Native South American populations via ancient DNA Doctor of Philosophy Doctorate Full Time Ms Evelyn Jane Collen
    2019 Co-Supervisor Genetic History of Pre-Columbian Mesoamerica Doctor of Philosophy Doctorate Full Time Mr Xavier Roca Rada
    2018 Co-Supervisor Reconstructing the Population History of Wallacea and Sahul Doctor of Philosophy Doctorate Full Time Mr Gludhug Ariyo Purnomo
  • Position: ARC Research Associate
  • Phone: 83135565
  • Email: joao.teixeira@adelaide.edu.au
  • Fax: 8313 4364
  • Campus: North Terrace
  • Building: Darling, floor 2
  • Room: 2 05c
  • Org Unit: Ecology and Evolutionary Biology

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