Associate Professor Jingxiu Bi

Associate Professor

School of Chemical Engineering and Advanced Materials

Faculty of Engineering, Computer and Mathematical Sciences

Eligible to supervise Masters and PhD, but is currently at capacity - email supervisor to discuss availability.

I have more than 20 years experience in the research, teaching and pharmaceutical industrial consulting in the field of bioprocess design and optimization for biopharmaceutical product process development, both in fundamental and applied research. About 80 publications and 6 patents have been published. My current research main focus on:

1) Virus-like particles protein and modified protein as drug /vaccine carriers for cancer and disease treatment;
2) Biodegradable material development for gene/drug delivery
3) High through-put and scalable bioprocess development, integration and optimization;
4) Biomedical devices/biomaterials development for burn healing
5) Bioactive components screening and process development from traditional Chinese Medicines and formulation

My Research
Career
Publications
Grants and Funding
Teaching
Supervision
Contact

I have more than 20 years experience in the research, teaching and industrial consultant in the field of bioprocess design and optimization for biopharmaceutical product process development, both in fundamental and applied research. About 80 publications and 6 patents have been published. My current research main focus on:

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Appointments

Date	Position	Institution name
2014 - 2014	Visiting Professor	Hamburg University of Technology, Hamburg
2007	Associate Professor	The University of Adelaide
2004 - 2007	Associate Professor	Institute of Process Engineering, Chinese Academy of Sciences
2002 - 2004	Research Fellow	University of Birmingham, Birmingham
1999 - 2001	Postdoctoral Researcher	Helmholtz Centre for Infection Research (HZ), Brunswick
1993 - 1999	Research Assistant	Institute of Process Engineering, Chinese Academy of Sciences

Language Competencies

Language Competency
Chinese (Mandarin) Can read, write, speak, understand spoken and peer review
English Can read, write, speak, understand spoken and peer review

Language	Competency
Chinese (Mandarin)	Can read, write, speak, understand spoken and peer review
English	Can read, write, speak, understand spoken and peer review

Education

Date	Institution name	Country	Title
1996 - 1999	Institute of Process Engineering, Chinese Academy of Sciences	China	PhD of Chemical Engineering
1990 - 1993	Institute of Process Engineering, Chinese Academy of Sciences	China	Master of Biochemical Engineering
1986 - 1990	Beijing University of Technology and Commerce	China	Bachelor of Biochemical Engineering

Research Interests

Biomaterials Biomedical Engineering Bioprocessing, Bioproduction and Bioproducts Biotechnology Gene and Molecular Therapy Nanobiotechnology Preventive Medicine

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Journals

Year	Citation
2018	Zhu, H., Tian, L., Zhang, L., Bi, J., Song, Q., Yang, H., & Qiao, J. (2018). Preparation, characterization and antioxidant activity of polysaccharide from spent Lentinus edodes substrate. International Journal of Biological Macromolecules, 112, 976-984. DOI Scopus12 WoS10
2018	Zhang, J., Yun, S., Bi, J., Dai, S., Du, Y., Zannettino, A., & Zhang, H. (2018). Enhanced multi-lineage differentiation of human mesenchymal stem/stromal cells within poly(N -isopropylacrylamide-acrylic acid) microgel-formed three-dimensional constructs. Journal of Materials Chemistry B, 6(12), 1799-1814. DOI Scopus1 WoS1
2018	Guo, F., Liu, Y., Zhang, C., Wang, Q., Wang, L., Gao, Y., . . . Su, Z. (2018). Prompt and Robust Humoral Immunity Elicited by a Conjugated Chimeric Malaria Antigen with a Truncated Flagellin. Bioconjugate Chemistry, 29(3), 761-770. DOI Scopus3 WoS2 Europe PMC1
2018	Cui, X., Tang, J., Hartanto, Y., Zhang, J., Bi, J., Dai, S., . . . Zhang, H. (2018). NIPAM-based microgel microenvironment regulates the therapeutic function of cardiac stromal cells. ACS Applied Materials and Interfaces, 10(44), 37783-37796. DOI Scopus4 WoS4
2018	Cui, X., Hartanto, Y., Wu, C., Bi, J., Dai, S., & Zhang, H. (2018). Tuning microenvironment for multicellular spheroid formation in thermo-responsive anionic microgel scaffolds. Journal of Biomedical Materials Research - Part A, 106(11), 2899-2909. DOI Scopus1
2017	Liu, L., Zhang, C., Li, Z., Wang, C., Bi, J., Yin, S., . . . Su, Z. (2017). Albumin binding domain fusing R/K-X-X-R/K sequence for enhancing tumor delivery of doxorubicin. Molecular Pharmaceutics, 14(11), 3739-3749. DOI Scopus2 WoS2
2017	Mellati, A., Fan, C., Tamayol, A., Annabi, N., Dai, S., Bi, J., . . . Zhang, H. (2017). Microengineered 3D cell-laden thermoresponsive hydrogels for mimicking cell morphology and orientation in cartilage tissue engineering. Biotechnology and Bioengineering, 114(1), 217-231. DOI Scopus27 WoS22 Europe PMC3
2017	Zhang, B., Zhang, H., Dai, S., & Bi, J. (2017). Cell-penetrating peptide-labelled smart polymers for enhanced gene delivery. Engineering in Life Sciences, 17(2), 193-203. DOI Scopus1 WoS1
2016	Cui, X., Liu, Y., Hartanto, Y., Bi, J., Dai, S., & Zhang, H. (2016). Multicellular spheroids formation and recovery in microfluidics-generated thermoresponsive microgel droplets. Colloid and Interface Science Communications, 14, 4-7. DOI Scopus6 WoS6
2016	Mellati, A., Valizadeh Kiamahalleh, M., Dai, S., Bi, J., Jin, B., & Zhang, H. (2016). Influence of polymer molecular weight on the in vitro cytotoxicity of poly (N-isopropylacrylamide). Materials Science and Engineering C, 59, 509-513. DOI Scopus11 WoS11 Europe PMC3
2016	Xiong, L., Bi, J., Tang, Y., & Qiao, S. (2016). Magnetic core-shell silica nanoparticles with large radial mesopores for siRNA delivery. Small, 12(34), 4735-4742. DOI Scopus32 WoS34 Europe PMC13
2016	Mellati, A., Kiamahalleh, M., Madani, S., Dai, S., Bi, J., Jin, B., & Zhang, H. (2016). Poly(N-isopropylacrylamide) hydrogel/chitosan scaffold hybrid for three-dimensional stem cell culture and cartilage tissue engineering. Journal of Biomedical Materials Research Part A, 104(11), 2764-2774. DOI Scopus19 WoS18 Europe PMC7
2016	Cui, X., Dini, S., Dai, S., Bi, J., Binder, B., Green, J., & Zhang, H. (2016). A mechanistic study on tumour spheroids formation in thermosensitive hydrogels: experiments and mathematical modelling. RSC Advances, 6(77), 73282-73291. DOI Scopus12 WoS10
2015	Yu, Y., Liang, W., Bi, J., Geng, Y., Kang, Z., & Zhao, Y. (2015). Thermophysical experiment and numerical simulation on thermal cracking of oil shale at high temperature. Yanshilixue Yu Gongcheng Xuebao/Chinese Journal of Rock Mechanics and Engineering, 34(6), 1106-1115. DOI Scopus4
2015	Xiong, L., Du, X., Shi, B., Bi, J., Kleitz, F., & Qiao, S. (2015). Tunable stellate mesoporous silica nanoparticles for intracellular drug delivery. Journal of Materials Chemistry B, 3(8), 1712-1721. DOI Scopus30 WoS31
2015	Modra, K., Dai, S., Zhang, H., Shi, B., & Bi, J. (2015). Polycation-mediated gene delivery: challenges and considerations for the process of plasmid DNA transfection. Engineering in Life Sciences, 15(5), 489-498. DOI Scopus18 WoS17
2015	Cui, X., Bi, J., Dai, S., & Ye, H. (2015). Single-cell analysis for bioprocessing. Engineering in Life Sciences, 15(6), 582-592. DOI Scopus2 WoS2
2014	Mellati, A., Dai, S., Bi, J., Jin, B., & Zhang, H. (2014). A biodegradable thermosensitive hydrogel with tuneable properties for mimicking three-dimensional microenvironments of stem cells. RSC Advances, 4(109), 63951-63961. DOI Scopus25 WoS21
2014	Shi, B., Zhang, H., Qiao, S., Bi, J., & Dai, S. (2014). Intracellular microenvironment-responsive label-free autofluorescent nanogels for traceable gene delivery. Advanced Healthcare Materials, 3(11), 1839-1848. DOI Scopus19 WoS22 Europe PMC9
2014	Shen, Z., Mellati, A., Bi, J., Zhang, H., & Dai, S. (2014). A thermally responsive cationic nanogel-based platform for three-dimensional cell culture and recovery. RSC Advances, 4(55), 29146-29156. DOI Scopus15 WoS15
2014	Shi, B., Zhang, H., Bi, J., & Dai, S. (2014). Endosomal pH responsive polymers for efficient cancer targeted gene therapy. Colloids and Surfaces B: Biointerfaces, 119, 55-65. DOI Scopus20 WoS20 Europe PMC4
2014	Shi, B., Zhang, H., Dai, S., Du, X., Bi, J., & Qiao, S. (2014). Intracellular microenvironment responsive polymers: a multiple-stage transport platform for high-performance gene delivery. Small, 10(5), 871-877. DOI Scopus20 WoS23 Europe PMC10
2013	Elliott, P., Bi, J., & Zhang, H. (2013). Quality by design for biopharmaceuticals: a historical review and guide for implementation. Pharmaceutical Bioprocessing, 1(1), 105-122. DOI
2013	Du, X., Shi, B., Liang, J., Bi, J., Dai, S., & Qiao, S. (2013). Developing functionalized dendrimer-like silica nanoparticles with hierarchical pores as advanced delivery nanocarriers. Advanced Materials, 25(41), 5981-5985. DOI Scopus108 WoS110 Europe PMC38
2013	Geng, J., Bi, J., Zeng, A., & Yuan, J. Q. (2013). Application of hybrid cybernetic model in simulating myeloma cell culture co-consuming glucose and glutamine with mixed consumption patterns. Process Biochemistry, 48(5-6), 955-964. DOI Scopus5 WoS4
2013	Mijajlovic, M., Wright, D., Zivkovic, V., Bi, J., & Biggs, M. (2013). Microfluidic hydrodynamic focusing based synthesis of POPC liposomes for model biological systems. Colloids and Surfaces B-Biointerfaces, 104, 276-281. DOI Scopus29 WoS26 Europe PMC6
2013	Shi, B., Zhang, H., Shen, Z., Bi, J., & Dai, S. (2013). Developing a chitosan supported imidazole Schiff-base for high-efficiency gene delivery. Polymer Chemistry, 4(3), 840-850. DOI Scopus31 WoS31
2012	Shen, Z., Bi, J., Shi, B., Nguyen, D., Xian, C., Zhang, H., & Dai, S. (2012). Exploring thermal reversible hydrogels for stem cell expansion in three-dimensions. Soft Matter, 8(27), 7250-7257. DOI Scopus23 WoS23
2012	Shi, B., Deng, L., Shi, X., Dai, S., Zhang, H., Wang, Y., . . . Guo, M. (2012). The enhancement of neural stem cell survival and growth by coculturing with expanded sertoli cells in vitro. Biotechnology Progress, 28(1), 196-205. DOI Scopus8 WoS8 Europe PMC3
2012	Shen, Z., Shi, B., Zhang, H., Bi, J., & Dai, S. (2012). Exploring low-positively charged thermosensitive copolymers as gene delivery vectors. Soft Matter, 8(5), 1385-1394. DOI Scopus19 WoS19
2012	Shi, B., Shen, Z., Zhang, H., Bi, J., & Dai, S. (2012). Exploring N-Imadozolyl-O-Carboxymethyl Chitosan for High Performance Gene Delivery. Biomacromolecules, 13(1), 146-153. DOI Scopus55 WoS51 Europe PMC21
2011	Zhang, H., Dai, S., Bi, J., & Liu, K. (2011). Biomimetic three-dimensional microenvironment for controlling stem cell fate. Interface Focus, 1(5), 792-803. DOI Scopus43 WoS38 Europe PMC21
2011	Shen, Z., Wei, W., Tanaka, H., Kohama, K., Ma, G., Dobashi, T., . . . Dai, S. (2011). A galactosamine-mediated drug delivery carrier for targeted liver cancer therapy. Pharmacological Research, 64(4), 410-419. DOI Scopus54 WoS55 Europe PMC20
2011	Shen, Z., Li, Y., Kohama, K., O'Neill, B., & Bi, J. (2011). Improved drug targeting of cancer cells by utilizing actively targetable folic acid-conjugated albumin nanospheres. Pharmacological Research, 63(1), 51-58. DOI Scopus83 WoS72 Europe PMC32
2010	Huang, Y., Bi, J., Zhao, L., Ma, G., & Su, Z. (2010). Regulation of protein multipoint adsorption on ion-exchange adsorbent and its application to the purification of macromolecules. Protein Expression and Purification, 74(2), 257-263. DOI Scopus20 WoS19 Europe PMC8
2010	Zhang, Y., Luo, J., Bi, J., Wang, J., Sun, L., Liu, Y., . . . Su, Z. (2010). Efficient separation of homologous α-lactalbumin from transgenic bovine milk using optimized hydrophobic interaction chromatography. Journal of Chromatography A, 1217(23), 3668-3673. DOI Scopus13 WoS8 Europe PMC3
2010	Shi, B., Zhang, S., Wang, Y., Zhuang, Y., Chu, J., Zhang, S., . . . Guo, M. (2010). Expansion of mouse sertoli cells on microcarriers. Cell Proliferation, 43(3), 275-286. DOI Scopus10 WoS9 Europe PMC6
2009	Lu, Y., Wang, L., Xue, Y., Zhang, C., Xing, X., Lou, K., . . . Su, Z. (2009). Production of violet pigment by a newly isolated psychrotrophic bacterium from a glacier in Xinjiang, China. Biochemical Engineering Journal, 43(2), 135-141. DOI Scopus39 WoS31
2008	Zhou, F., Bi, J., Zeng, A., & Yuan, J. (2008). Modeling of the cell cycle for myeloma cell culture. Shanghai Jiaotong Daxue Xuebao/Journal of Shanghai Jiaotong University, 42(7), 1207-1210.
2008	Wu, T., Huang, Y., Bi, J., Zhang, Y., Sun, L., Sun, C., & Su, Z. (2008). Effect of solution environment on the purification of pertussis toxin. Chinese Journal of Biotechnology, 24(7), 1279-1284. DOI Scopus1
2008	Liu, Y., Bi, J., Zeng, A., & Yuan, J. (2008). A cybernetic model to describe the dynamics of myeloma cell cultivations. Applied Mathematics and Computation, 205(1 Sp Iss), 84-97. DOI Scopus6 WoS6
2008	Liu, Y., Bi, J., Zeng, A., & Yuan, J. (2008). A simple kinetic model for myeloma cell culture with consideration of lysine limitation. Bioprocess and Biosystems Engineering, 31(6), 569-577. DOI Scopus12 WoS12 Europe PMC4
2007	Liu, Y., Bi, J., Zeng, A., & Yuan, J. (2007). A Population Balance Model Describing the Cell Cycle Dynamics of Myeloma Cell Cultivation. Biotechnology Progress, 23(5), 1198-1209. DOI Scopus22 WoS23 Europe PMC17
2007	Li, R., Li, Y., Bi, J., Zhao, L., Zhou, W., Huang, Y., . . . Su, Z. (2007). Comparison of Adsorbent with Varying Spacer Arm Length and Ligand Density for the Purification of Recombinant Hepatitis B Virus Surface Antigen. Chinese Journal of Biotechnology, 23(4), 692-699. DOI
2007	Zhou, F., Bi, J., Zeng, A., & Yuan, J. (2007). A macrokinetic model for myeloma cell culture based on stoichiometric balance. Biotechnology and Applied Biochemistry, 46(2), 85-95. DOI Scopus4 WoS3 Europe PMC3
2007	Li, Y., Bi, J., Zhou, W., Huang, Y., Sun, L., Zeng, A., . . . Su, Z. (2007). Characterization of the large size aggregation of Hepatitis B virus surface antigen (HBsAg) formed in ultrafiltration process. Process Biochemistry, 42(3), 315-319. DOI Scopus23 WoS20
2007	Zhou, W., Bi, J., Zhao, L., Wang, Y., Li, Y., Huang, Y., . . . Su, Z. (2007). A highly efficient hydrophobic interaction chromatographic absorbentnext term improved the purification of hepatitis B surface antigen (HBsAg) derived from Hansenula polymorpha cell. Process Biochemistry, 42(5), 751-756. DOI Scopus13 WoS11
2007	Yu, P., Zhang, G., Bi, J., Lu, X., Wang, Y., & Su, Z. (2007). Facile purification of mono-PEGylated interleukin-1 receptor antagonist and its characterization with multi-angle laser light scattering. Process Biochemistry, 42(6), 971-977. DOI Scopus11 WoS11
2007	Zheng, C., Bi, J., Ma, G., & Su, Z. (2007). Polyethylene glycol improves conjugation of bovine hemoglobin and human serum albumin in a controlled ratio. Artificial Cells Blood Substitutes and Immobilization Biotechnology, 35(6), 568-584. DOI Scopus1 WoS1
2007	Huang, Y., Bi, J., Zhang, Y., Zhou, W., Li, Y., Zhao, L., & Su, Z. (2007). A highly efficient integrated chromatographic procedure for the purification of recombinant hepatitis B surface antigen from Hansenula polymorpha. Protein Expression and Purification, 56(2), 301-310. DOI Scopus26 WoS21 Europe PMC8
2006	Zhang, Y., Bi, J., Zhou, W., Li, Y., Dong, A., Sun, J., & Su, Z. (2006). Purification of recombinant hepatitis B virus surface antigen with peg precipitation and chromatography. Guocheng Gongcheng Xuebao/The Chinese Journal of Process Engineering, 6(1), 100-103. Scopus2
2006	Wang, Y., Bi, J., Zhao, L., Zhou, W., Li, Y., Huang, Y., . . . Su, Z. (2006). Development of a new hydrophobic interaction chromatography absorbent and its application to the purification of recombinant hepatitis B surface antigen. Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 22(2), 278-284. Scopus1
2006	Zhou, F., Bi, J., Zeng, A., & Yuan, J. (2006). A macrokinetic and regulator model for myeloma cell culture based on metabolic balance of pathways. Process Biochemistry, 41(10), 2207-2217. DOI Scopus12 WoS9
2006	Zhou, W., Bi, J., Janson, J., Li, Y., Huang, Y., Zhang, Y., & Su, Z. (2006). Molecular characterization of recombinant Hepatitis B surface antigen from Chinese hamster ovary and Hansenula polymorpha cells by high-performance size exclusion chromatography and multi-angle laser light scattering. Journal of Chromatography. B, Analytical Techniques in the Biomedical and Life Sciences, 838(2), 71-77. DOI Scopus34 WoS27 Europe PMC14
2006	Huang, Y., Bi, J., Zhou, W., Wang, Y., Ma, G., & Su, Z. (2006). Improving recovery of recombinant hepatitis B virus surface antigen by ion-exchange chromatographic supports with low ligand density. Process Biochemistry, 41(11), 2320-2326. DOI Scopus28 WoS24
2005	Yun, Q., Chen, T., Zhang, G., Bi, J., Ma, G., & Su, Z. (2005). Novel polyethylene glycol derivative suitable for the preparation of mono-PEGylated protein. Biotechnology Letters, 27(3), 213-217. DOI Scopus3 WoS2
2005	Yun, Q., Yang, R., Chen, T., Bi, J., Ma, G., & Su, Z. (2005). Reproducible preparation and effective separation of PEGylated recombinant human granulocyte colony-stimulating factor with novel “PEG-pellet” PEGylation mode and ion-exchange chromatography. Journal of Biotechnology, 118(1), 67-74. DOI Scopus15 WoS15 Europe PMC8
2005	Zhi, W., Song, J., Ouyang, F., & Bi, J. (2005). Application of response surface methodology to the modeling of α-amylase purification by aqueous two-phase systems. Journal of Biotechnology, 118(2), 157-165. DOI Scopus43 WoS38 Europe PMC13
2005	Zhou, W., Bi, J., Janson, J., Dong, A., Li, Y., Zhang, Y., . . . Su, Z. (2005). Ion-exchange chromatography of hepatitis B virus surface antigen from a recombinant Chinese hamster ovary cell line. Journal of Chromatography A, 1095(1-2), 119-125. DOI Scopus25 WoS26 Europe PMC10
2005	Li, X., Sun, H., Zhang, G., Bi, J., Ma, G., Ma, R., & Su, Z. (2005). A cyanopropyl reversed phase chromatography enables resolution of huperzine A and B on analytical and preparative scales. Journal of Separation Science, 28(17), 2363-2369. DOI Scopus1 WoS1
2005	Zhang, F., Bi, J., Zeng, A., & Yuan, J. (2005). Simple kinetic model for myeloma cell growth with lysine as a limiting substrate. Shanghai Jiaotong Daxue Xuebao/Journal of Shanghai Jiaotong University, 39(SUPPL.), 182-186.
2005	Bi, J., Zhou, W., Li, Y., Huang, Y., Zhang, Y., Dong, A., & Su, Z. (2005). Polyethylene glycol-accompanied ion-exchange chromatography to purify recombinant hepatitis B virus surface antigen. Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 21(6), 947-953. Scopus3
2005	Chen, T., Yun, Q., Bi, J., Ma, G., & Su, Z. (2005). Separation and purification of PEGylated rhG-CSF by two-step ion-exchange chromatography. Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 21(2), 284-288.
2004	Bi, J., Shuttleworth, J., & Al-Rubeai, M. (2004). Uncoupling of cell growth and proliferation results in enhancement of productivity in p21CIP1-arrested CHO cells. Biotechnology and Bioengineering, 85(7), 741-749. DOI Scopus87 WoS85 Europe PMC59
2004	Yun, Q., He, M., Xing, W., Bi, J., Ma, G., & Su, Z. (2004). A novel tetrafunctional reagent for simultaneous intramolecular and intermolecular cross-linking of bovine hemoglobin. Biotechnology Letters, 26(17), 1359-1363. DOI Scopus3 WoS3 Europe PMC1
2004	Zhi, W., Song, J., Bi, J., & Ouyang, F. (2004). Partial purification of α-amylase from culture supernatant of Bacillus subtilis in aqueous two-phase systems. Bioprocess and Biosystems Engineering, 27(1), 3-7. DOI Scopus25 WoS22 Europe PMC8
2003	Bi, J., Buhr, P., Zeng, A., & Wirth, M. (2003). Human c-fos promoter mediates high-level, inducible expression in various mammalian cell lines. Biotechnology and Bioengineering, 81(7), 848-854. DOI Scopus3 WoS4 Europe PMC2
2003	Ibarra, N., Bi, J., Shuttleworth, J., Al-Rubeai, M., & Watanabe, S. (2003). Modulation of Cell Cycle for Enhancement of Antibody Productivity in Perfusion Culture of NS0 Cells. Biotechnology Progress, 19(1), 224-228. DOI WoS43 Europe PMC27
2002	Bi, J., Wirth, M., Beer, C., Kim, E., Guc, M., & Zeng, A. (2002). Dynamic characterization of recombinant Chinese Hamster Ovary cells containing an inducible c-fos promoter GFP expression system as a biomarker. Journal of Biotechnology, 93(3), 231-242. DOI Scopus21 WoS19 Europe PMC9
1996	Bi, J., Ouyang, F., Liu, D., Guo, Z., Gui, Y., & Yang, Y. (1996). Studies of technical conditions of somatic embryogenesis in cell suspension culture of Apium graveolens. Acta Botanica Sinica, 38(6), 451-456.

Conference Papers

Year	Citation
2010	Shi, B., Guo, M., & Bi, J. (2010). Optimization of Expansion of Mouse Sertoli Cells on Microcarriers and Potential Application in Co-Culture with Nerve Stem Cells. In Proceedings of the Chemeca 2010 Conference Vol. 2010. Adelaide, Australia.

Conference Items

Year	Citation
2013	Shi, B., Zhang, M., Bi, J., & Dai, S. (2013). Development of a novel folic acid chitosan supported imidazole Schiff base for tumor targeted gene delivery system and drug therapy. Poster session presented at the meeting of Conference abstracts of the Symposium on Innovative Polymers for Controlled Delivery, as published in Journal of Controlled Release. Elsevier. DOI WoS4
2008	Bi, J., Huang, Y., Su, Z., King, K., & Middelberg, A. (2008). Mechanism and controlled purification of self-assembly virus like particles in bioprocess. Poster session presented at the meeting of Abstracts of the 13th International Biotechnology Symposium & Exhibition (IBS-2008): Biotechnology for Sustainability of Human Society, as published in Journal of Biotechnology. Dalian, China: Elsevier BV. DOI
2008	Bi, J., Huang, Y., Su, Z., King, K., & Middelberg, A. (2008). Mechanism and controlled purification of self-assembly virus like particles in bioprocess. Poster session presented at the meeting of Abstracts of the 13th International Biotechnology Symposium & Exhibition (IBS-2008): Biotechnology for Sustainability of Human Society, as published in Journal of Biotechnology. Dalian, China: Elsevier BV. DOI

DVCR-Research Facility Fund--Biorpocess Facility Fund, AP Jingxiu Bi, $685,000, 2018
Contract Research (ARI, A135382), Characterization and evaluation of mussel adhesive protein (MAP) in vitro cell/tissue culture; Funded by Jiangyin Usun Technology Co. Ltd, Sole CI, $100,000. 2015-2017
DAAD-Gro8 Research Fund; Bio-system study for mammalian cell transient transfection, Sole CI, $10,000; 2014
Innovative Production Platform for Mussel Adhesive Protein (MAP), Prof. Christodoulos A. Floudas (University of Princeton, USA), Dr Jingxiu Bi, (The University of Adelaide), and Prof. Ming Gu, (Institute of Process Engineering, Chinese Academy of Sciences) supported by Department of Science and Technology of Jiangsu Province, China, RMB3,000,000 (Au$ 600,000), 2014-2016
AKTA System-High Throughput Protein Purification Platform; Dr Jingxiu Bi, DVCR Equipment Fund, $120,000; 2012
Detection of Virus like particles aggregation in downstream process, Faculty of EMCS Cat-1 Improvement Scheme, Sole CI, $15,000; 2011
Transient Production of Therapeutic Compounds, Prof. Wei Zhang, Prof. Chris Franco (Flinders Uni.), Dr Jingxiu Bi and Dr Hu Zhang (UniA), MLA (Meat Livestock Australia, Project Number: A.BIT.0017) Innovation Fund, $350,000; 2010
Prediction of Binding Capacity of VLPs on the Surface of Ionic Absorbents, Faculty of EMCS Cat-1 Improvement Scheme, Sole CI, $25,000; 2009
Innovative Hydrogen Bond Absorbents Development for Peptide Purification, Chinese Pharmaceutical Industrial Innovative Technology Fund, Prof. Ming Gu, and Dr Jingxiu Bi 2 years, RMB 300,000 (AU $56,000); 2008
Self-Assemble of Virus like particles induced by harsh chemical condition in downstream process,; The University of Adelaide, Faculty of ECMS new staff start-up, Sole CI, $10,000; 2007
Recombinant Protein Purification from Transgenic Milk, Chinese “863” High-Tech. Research Grant, 2 years, Sole CI, RBM 1000,000 (around AU$178,000); 2007

COURSE TAUGHT (PAST 5 YEARS)
COURSE TITLE	YEAR LEVEL	YEAR TAUGHT	CLASS SIZE	DUTIES PERFORMED
Pharmaceutical Production Processes	II	2012-Now	25	New course, subject coordinator and sole lecturer
Introduction of Pharmaceutical Engineering	I	2012-2013	25	New Course, subject coordinator and sole lecturer
Pharmaceutical Project and Experiment Design	III	2013-Now	25	New course, subject coordinator and sole lecturer
Chemical Engineering Experiment Design	III	2013-2014	82	Subject coordinator and co-lecturer
Introduction of Process Engineering	I	2013-2014	135	Co-lecturer
Principles of Biotechnology	II	2013-now	24	Subject coordinator and co-lecturer
Pharmaceutical Process Validation and Quality Control	IV	2014-Now	20	New course, subject Coordinator and sole lecturer
Pharmaceutical Plant Design Project	IV	2010-now	6	Co-Lecturer

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Current Higher Degree by Research Supervision (University of Adelaide)

Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
2019	Principal Supervisor	Developing a continuous bioseparation process for a VLP-based Group A Streptococcus vaccine	Doctor of Philosophy	Doctorate	Full Time	Mr Lukas Gerstweiler
2018	Principal Supervisor	Ferritin as Protein Nanoparticle Delivery Platform - Molecular Dynamic and Experiment Simulation	Doctor of Philosophy	Doctorate	Full Time	Miss Yiran Qu
2018	Principal Supervisor	Optimization of Microbial Fermentation in VLP vaccines	Master of Philosophy	Master	Full Time	Mr Nhat Hoang Huynh
2018	Principal Supervisor	Development of novel antimicrobial nanomaterials for surface elimination of persistent bacteria	Doctor of Philosophy	Doctorate	Full Time	Mr Afshin Karami
2017	Co-Supervisor	Computational Study and Experiments of Nanoscale Metal-Organic Frameworks as Drug Carrier for Brain Diseases	Doctor of Philosophy	Doctorate	Full Time	Mr Yechuan Zhang
2017	Co-Supervisor	Developing a Nanocomposite Device for Rapid analysis of Bacteria	Doctor of Philosophy	Doctorate	Full Time	Ms Thai Thao Ly
2016	Principal Supervisor	An Efficient Site Specific Conjugated Vaccine Development System	Doctor of Philosophy	Doctorate	Full Time	Mr Bingyang Zhang
2016	Principal Supervisor	Development of Novel Functional Sun-Screen Materials	Doctor of Philosophy	Doctorate	Full Time	Miss Shuang Yin

Past Higher Degree by Research Supervision (University of Adelaide)

Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
2015 - 2019	Co-Supervisor	Intracellular Microenvironment Triggered Co-delivery of Anticancer Drugs and Genes	Doctor of Philosophy	Doctorate	Full Time	Mr Seonho Yun
2013 - 2015	Co-Supervisor	Smart Drug Conjugated Silica Nanoparticles for Controlled and Sustained Release	Master of Philosophy	Master	Full Time	Ms Wanxia Zhao
2013 - 2017	Co-Supervisor	Mesoporous Silica Nanocomposites for Drug and Gene Delivery	Doctor of Philosophy	Doctorate	Full Time	Mr Lin Xiong
2013 - 2015	Principal Supervisor	Intracellular Microenvironment Responsive Nanogels for Gene Delivery	Master of Philosophy	Master	Full Time	Mr Bingyang Zhang
2013 - 2017	Co-Supervisor	Thermoresponsive Microgels for Multicellular Spheroids Formation	Doctor of Philosophy	Doctorate	Full Time	Mr Xiaolin Cui
2013 - 2016	Principal Supervisor	Microfluidic System Development for Drug Delivery	Master of Engineering Science	Master	Full Time	Mengjue Zhang
2013 - 2016	Principal Supervisor	Mechanism of Bevacinzumab Adsorption with Affinity Ligands and Bioprocess Optimization for Antibody Purification	Master of Engineering Science	Master	Full Time	Yuzhe Tang
2011 - 2015	Principal Supervisor	Quality by Design for the Downstream Processing of Biopharmaceuticals	Doctor of Philosophy	Doctorate	Full Time	Mr Phillip Wayne Elliott
2010 - 2014	Principal Supervisor	Enhancement of Gene Therapy by Exploring Functional Gene Vectors Based on Chitosan Modification.	Doctor of Philosophy	Doctorate	Full Time	Mr Bingyang Shi
2009 - 2015	Co-Supervisor	Molecular Dynamics Study of Peptide Adsorption at Liquid/Solid Interfaces	Doctor of Philosophy	Doctorate	Full Time	Mr Matthew John Penna

Position: Associate Professor
Phone: 83134118
Email: jingxiu.bi@adelaide.edu.au
Campus: North Terrace
Building: Engineering North
Room: 108
Org Unit: School of Chemical Engineering and Advanced Materials

Associate Professor Jingxiu Bi

Appointments

Language Competencies

Education

Research Interests

Journals

Conference Papers

Conference Items

Current Higher Degree by Research Supervision (University of Adelaide)

Past Higher Degree by Research Supervision (University of Adelaide)

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