
Jill Chmielewski
Higher Degree by Research Candidate
School of Biological Sciences
Faculty of Sciences, Engineering and Technology
My PhD research focuses on two malaria parasite species: Plasmodium falciparum, which is responsible for the majority of malarial deaths, and P. knowlesi which is a zoonotic species (transmits from monkeys to humans). Specifically, I utilise gene editing (CRISPR-Cas9) to remove proteins from the surface of the parasite as it replicates in the blood stream. This allows me to determine how important these proteins are for the parasite to replicate successfully as well as assess whether it is a potential vaccine target.
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Journals
Year Citation 2021 Davidson, M. S., Andradi-Brown, C., Yahiya, S., Chmielewski, J., O'Donnell, A. J., Gurung, P., . . . Baum, J. (2021). Automated detection and staging of malaria parasites from cytological smears using convolutional neural networks. Biological imaging, 1, e2-1-e2-13.
Europe PMC7
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