Dr Jiawen Li
Dr. Jiawen Li received her BS degree in Optical Engineering from Zhejiang University in 2010, and her PhD degree in Biomedical Engineering from University of California Irvine in 2015. Her research interests include optical coherence tomography (OCT), imaging+sensing fibre-optic probes, Doppler OCT, multimodality imaging and ultra-thin endoscopes.
Her PhD research focused on the development of highly novel multimodal miniaturized fibre-optic imaging probes, where they fully integrated two or more complementary imaging modalities in one single unit.
After the completion of her PhD, She joined University of Western Australian (UWA) to lead the development of a flexible fibre-optic needle probe. Extended from this project, she proposed an innovative fibre-optic probe design that can provide co-localized imaging and aspiration. This was the cornerstone idea of an awarded grant (as the lead CI) and a journal publication (as the first and corresponding author, which also won IPAS Best ECR Paper Award).
In April 2016, she moved with her supervisor, Prof Robert McLaughlin, to University of Adelaide (UoA) to establish their new lab. They conducted a successful pilot clinical trial of our smart brain needle probes in 11 patients undergoing neurosurgery in late 2016. The tiny probe lets surgeons 'see' at-risk blood vessels as they insert the biopsy needle, allowing them to avoid causing potentially fatal bleeds. The results have been highlighted by ‘making a difference: outcomes of ARC supported research’.
Since 2017, she began to establish her own independent research area by actively applying for grants and delivering them. 1) As the lead CI of an awarded pilot project grant, she was able to investigate and demonstrate the first single-fibre based fibre-optic probe that can conduct imaging and temperature sensing simultaneously. 2) Strategically using the funding of her women’s research excellence award, she developed my unique expertise of 3D printing freeform micro-optics for fibre-optic probes (first-author journal paper under in-depth review by Scientific Reports) and strengthened her collaborative work on developing biocompatible fibre coatings. 3) Combining her unique expertise in fibre-optic probes and experience in research translation, she partner with Miniprobes Pty Ltd, a high-tech Australian start-up company, to translate our research outcomes to products suitable for industrial applications. She was recently awarded South Australian Government funding ‘Photonics Catalyst Program’, to support a University-Industry translational research project to develop fibre-optic imaging probes for the non-destructive testing market.
✓ Eligible to supervise Masters and PhD (as Co-Supervisor) — email supervisor to discuss availability.
High-resolution optical imaging technologies have rapidly gained importance, and a range of antibody-specific fluorescent biomarkers have driven new insights in disease mechanisms. However, optical techniques degrade rapidly in solid tissue due to absorption and multiple scattering of the photons, limiting their imaging depth and largely restricting their use to cell culture. To overcome this limit, we have been developing a series of multi-modal minimally-invasive imaging probes.
https://phys.org/news/2018-04-tiny-probe-body-temperatures.html
http://freshscience.org.au/state/sa/tiny-probe
http://www.octnews.org/articles/5026989/feature-of-the-week-11-24-13-miniature-oct-ivus-pr/
Appointments
| Date | Position | Institution name |
|---|---|---|
| 2016 | Postdoctoral Researcher-Lecturer (research-only) | University of Adelaide |
| 2015 - 2016 | Research Fellow | University of Western Australia |
| 2014 - 2014 | R&D intern | St. Jude Medical (United States) |
Awards and Achievements
| Date | Type | Title | Institution Name | Country | Amount |
|---|---|---|---|---|---|
| 2018 | Research Award | Faculty of Health and Medical Sciences Travel Award | Faculty of Health and Medical Sciences | Australia | $2800 |
| 2018 | Research Award | IPAS Best Early Career Researcher (ECR) Paper Award | Institute for Photonics and Advanced Sensing | Australia | — |
| 2018 | Award | ‘Women in Photonics’ Workshop Travel Award | Leibniz-IPHT | Germany | €800 |
| 2017 | Honour | Fresh Science SA Finalist | Fresh Science | Australia | — |
| 2017 | Research Award | Women's Research Excellence Award | The University of Adelaide | — | $5000 |
| 2016 | Research Award | Research Travel award | Adelaide Medical School | Australia | $3000 |
| 2016 | Research Award | Best poster award | The International Conference on Information Optics and Photonics | China | — |
| 2015 | Research Award | Robert Newcomb Interdisciplinary Team Science Award | University of California, Irvine | United States | — |
| 2015 | Research Award | Best technical poster | Optics in Cardiology conference | Netherlands | €750 |
| 2015 | Honour | Public Impact Fellow | UC Irvine | United States | $650 |
| 2013 | Award | Community Award | University of California, Irvine | United States | — |
| 2012 | Honour | Student Spotlight Report | University of California, Irvine | United States | — |
| 2012 | Achievement | 3rd Place in Business Plan Competition, Life Science Division | University of California, Irvine | United States | $3250 |
| 2011 | Fellowship | Graduate Growth Incentive Awards Fellowship | University of California, Irvine | United States | ~$60000 |
Education
| Date | Institution name | Country | Title |
|---|---|---|---|
| 2012 - 2015 | University of California, Irvine | USA | PhD |
| 2010 - 2012 | University of California, Irvine | USA | Master |
| 2006 - 2010 | Zhejiang University | China | Bachelor of science |
Research Interests
Journals
| Year | Citation |
|---|---|
| 2018 | Li, J. (2018). Perspective: Biomedical sensing and imaging with optical fibers-Innovation through convergence of science disciplines. APL Photonics, 3(10), 20 pages. DOI |
| 2018 | Li, J., Fejes, P., Lorenser, D., Quirk, B., Noble, P., Kirk, R., . . . McLaughlin, R. (2018). Two-photon polymerisation 3D printed freeform micro-optics for optical coherence tomography fibre probes. Scientific Reports, 8(1), 1-9. DOI |
| 2018 | Li, J., & E. Schartner, S. Musolino, B. Quirk, R. Kirk, H. Ebendorff-Heidepriem, R. McLaughlin. (2018). Miniaturized single-fiber-based needle probe for combined imaging and sensing in deep tissue. Optics Letters, 43(8), 1682-1685. DOI Scopus1 WoS1 |
| 2017 | Naqvi, A., Khedraki, R., Li, J., Chou, L. -D., Ramalingam, T., & Patel, P. (2017). HYBRID IVUS/OCT: "PROBING" THE FUTURE. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 69(11), 976. DOI |
| 2017 | Li, J., Quirk, B., Noble, P., Kirk, R., Sampson, D., & McLaughlin, R. (2017). Flexible needle with integrated optical coherence tomography probe for imaging during transbronchial tissue aspiration. Journal of Biomedical Optics, 22(10), 106002-1-106002-5. DOI Scopus2 WoS2 |
| 2016 | Li, J. (2016). 基于光学系统的血管内高集成多模态成像技术. 中国激光, 43(12), 1-13. DOI |
| 2016 | Li, J., & Chen, Z. (2016). Integrated intravascular ultrasound and optical coherence tomography technology: a promising tool to identify vulnerable plaques [INVITED PAPER]. Journal of Biomedical Photonics & Engineering, 1(4), 209-224. DOI |
| 2015 | Li, J., Minami, H., Steward, E., Ma, T., Mohar, D., Robertson, C., . . . Chen, Z. (2015). Optimal flushing agents for integrated optical and acoustic imaging systems. Journal of Biomedical Optics, 20(5), 056005. DOI WoS3 Europe PMC2 |
| 2015 | Li, J. (2015). Ultrafast optical-ultrasonic system and miniaturized catheter for imaging and characterizing atherosclerotic plaques in vivo. Scientific Reports, 5(1), 1-7. DOI WoS12 Europe PMC8 |
| 2015 | Piao, Z., Ma, T., Li, J., Wiedmann, M., Huang, S., Yu, M., . . . Chen, Z. (2015). High speed intravascular photoacoustic imaging with fast optical parametric oscillator laser at 1.7 μm. Applied Physics Letters, 107(8), 083701-1-083701-4. DOI WoS23 Europe PMC15 |
| 2015 | Ma, T., Yu, M., Chen, Z., Fei, C., Shung, K., & Zhou, Q. (2015). Multi-Frequency Intravascular Ultrasound (IVUS) Imaging. IEEE Trans Ultrason Ferroelectr Freq Control, 62(1), 97-107. DOI WoS43 Europe PMC19 |
| 2015 | Ma, T., Yu, M., Li, J., Munding, C. E., Chen, Z., Fei, C., . . . Zhou, Q. (2015). Multi-Frequency Intravascular Ultrasound (IVUS) Imaging (vol 62, pg 97, 2015). IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 62(3), 604. DOI WoS1 |
| 2014 | Liang, S., Ma, T., Jing, J., Li, X., Li, J., Kirk Shung, K., . . . Chen, Z. (2014). Trimodality imaging system and intravascular endoscopic probe: combined optical coherence tomography, fluorescence imaging and ultrasound imaging. Optics Letters, 39(23), 1-10. DOI WoS10 Europe PMC7 |
| 2014 | Li, J., Ma, T., Mohar, D., Correa, A., Zhou, Q., Patel, P. M., & Chen, Z. (2014). Integrated intravascular ultrasound (IVUS) optical coherence tomography (OCT) system for identifying thin-cap fibroatheroma. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 64(11), B111. DOI |
| 2014 | Li, J., Ma, T., Mohar, D., Correa, A., Zhou, Q., Chen, Z., & Patel, P. M. (2014). Human coronary plaque characterization using a fully integrated intravascular ultrasound and optical coherence tomography (IVUS-OCT) system. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 64(11), B108. DOI |
| 2014 | Li, X., Li, J., Jing, J., Ma, T., Liang, S., Zhang, J., . . . Chen, Z. (2014). Integrated IVUS-OCT Imaging for Atherosclerotic Plaque Characterization. IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS, 20(2), 8 pages. DOI WoS24 Europe PMC12 |
| 2014 | Li, J., Li, X., Mohar, D., Raney, A., Jing, J., Zhang, J., . . . Chen, Z. (2014). Integrated IVUS-OCT for Real-Time Imaging of Coronary Atherosclerosis. JACC-CARDIOVASCULAR IMAGING, 7(1), 101-103. DOI WoS20 Europe PMC13 |
| 2013 | Li, J., Ma, T., Jing, J., Zhang, J., Patel, P., Kirk Shung, K., . . . Chen, Z. (2013). Miniature optical coherence tomography-ultrasound probe for automatically coregistered three-dimensional intracoronary imaging with real-time display. Journal of Biomedical Optics, 18(10), 100502. DOI WoS15 Europe PMC9 |
| 2013 | Qi, W., Li, R., Ma, T., Li, J., Kirk Shung, K., Zhou, Q., & Chen, Z. (2013). Resonant acoustic radiation force optical coherence elastography. Applied Physics Letters, 103(10), 103704-1-103704-5. DOI WoS32 Europe PMC26 |
| 2012 | Liang, S., Saidi, A., Jing, J., Liu, G., Li, J., Zhang, J., . . . Chen, Z. (2012). Intravascular atherosclerotic imaging with combined fluorescence and optical coherence tomography probe based on a double-clad fiber combiner. Journal of Biomedical Optics, 17(7), 070501-1-070501-3. DOI WoS32 Europe PMC21 |
| 2012 | Li, J., Li, X., Jing, J., Mohar, D., Raney, A., Mahon, S., . . . Chen, Z. (2012). Integrated intravascular optical coherence tomography (OCT) - ultrasound (US) catheter for characterization of atherosclerotic plaques in vivo. 2012 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC), 2012, 3175-3178. DOI WoS4 Europe PMC3 |
| 2011 | Yin, J., Li, X., Jing, J., Li, J., Mukai, D., Mahon, S., . . . Chen, Z. (2011). Novel combined miniature optical coherence tomography ultrasound probe for in vivo intravascular imaging. Journal of Biomedical Optics, 16(6), 060505-1-060505-3. DOI WoS35 Europe PMC19 |
| 2010 | Meng, J., Ding, Z., Li, J., Wang, K., & Wu, T. (2010). Transit-time analysis based on delay-encoded beam shape for velocity vector quantification by spectral-domain Doppler optical coherence tomography. OPTICS EXPRESS, 18(2), 1261-1270. DOI WoS9 Europe PMC4 |
Conference Papers
| Year | Citation |
|---|---|
| 2016 | Piao, Z., Teng, M., Li, J., Qu, Y., Yu, M., Shung, K. K., . . . Chen, Z. (2016). High speed photoacoustic imaging with fast OPO laser at 1.7 pm (Conference Presentation). In A. Oraevsky, & L. Wang (Eds.), PHOTONS PLUS ULTRASOUND: IMAGING AND SENSING 2016 Vol. 9708 (pp. 1 page). San Francisco, CA: SPIE-INT SOC OPTICAL ENGINEERING. DOI |
| 2015 | Li, J., Ma, T., Cummins, T., Shung, K. K., Van Damb, J., Zhou, Q., & Chen, Z. (2015). Integrated OCT-US Catheter for Detection of Cancer in the Gastrointestinal Tract. In M. Suter, S. Lam, M. Brenner, G. Tearney, & T. Wang (Eds.), ENDOSCOPIC MICROSCOPY X; AND OPTICAL TECHNIQUES IN PULMONARY MEDICINE II Vol. 9304 (pp. 5 pages). San Francisco, CA: SPIE-INT SOC OPTICAL ENGINEERING. DOI |
| 2015 | Li, J., Minami, H., Steward, E., Ma, T., Mohar, D., Robertson, C., . . . Chen, Z. (2015). Ideal flushing agents for integrated optical acoustic imaging systems. In B. Choi, N. Kollias, H. Zeng, H. Kang, B. Wong, J. Ilgner, . . . A. Mandelis (Eds.), PHOTONIC THERAPEUTICS AND DIAGNOSTICS XI Vol. 9303 (pp. 6 pages). San Francisco, CA: SPIE-INT SOC OPTICAL ENGINEERING. DOI |
| 2014 | Li, J., Ma, T., Jing, J., Zhang, J., Patel, P. M., Shung, K. K., . . . Chen, Z. (2014). Back-to-back optical coherence tomography-ultrasound probe for co-registered three-dimensional intravascular imaging with real-time display. In J. Izatt, J. Fujimoto, & V. Tuchin (Eds.), OPTICAL COHERENCE TOMOGRAPHY AND COHERENCE DOMAIN OPTICAL METHODS IN BIOMEDICINE XVIII Vol. 8934 (pp. 7 pages). San Francisco, CA: SPIE-INT SOC OPTICAL ENGINEERING. DOI |
| 2014 | Li, J., Ma, T., Mohar, D., Correa, A., Minami, H., Jing, J., . . . Chen, Z. (2014). Diagnostic accuracy of an integrated intravascular ultrasound and optical coherence tomography (IVUS-OCT) system for coronary plaque characterization. In B. Choi, N. Kollias, H. Zeng, H. Kang, B. Wong, J. Ilgner, . . . A. Mandelis (Eds.), PHOTONIC THERAPEUTICS AND DIAGNOSTICS X Vol. 8926 (pp. 6 pages). San Francisco, CA: SPIE-INT SOC OPTICAL ENGINEERING. DOI WoS2 |
| 2014 | Li, J., Zhang, J., Chou, L., Wang, A., Jing, J., & Chen, Z. (2014). Self optical motion-tracking for endoscopic Optical coherence tomography probe using micro-beamsplitter probe. In B. Choi, N. Kollias, H. Zeng, H. Kang, B. Wong, J. Ilgner, . . . A. Mandelis (Eds.), PHOTONIC THERAPEUTICS AND DIAGNOSTICS X Vol. 8926 (pp. 7 pages). San Francisco, CA: SPIE-INT SOC OPTICAL ENGINEERING. DOI |
| 2013 | Ma, T., Li, J., Jing, J., Li, X., Patee, P. M., Shung, K. K., . . . Zhou, Q. (2013). Real-time Co-registered IVUS-OCT Catheter for Atherosclerotic Plaque Identification. In 2013 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IUS) (pp. 769-772). Prague, CZECH REPUBLIC: IEEE. DOI |
| 2012 | Li, J., Yin, J., Li, X., Jing, J., Mukai, D., Mahon, S., . . . Chen, Z. (2012). Miniature integrated optical coherence tomography (OCT) - ultrasound (US) probe for intravascular imaging. In N. Kollias, B. Choi, H. Zeng, H. Kang, B. Knudsen, B. Wong, . . . A. Mandelis (Eds.), PHOTONIC THERAPEUTICS AND DIAGNOSTICS VIII, PTS 1 AND 2 Vol. 8207 (pp. 7 pages). San Francisco, CA: SPIE-INT SOC OPTICAL ENGINEERING. DOI |
| 2012 | Jing, J., Li, J., Li, X., Yin, J., Zhang, J., Hoang, K., . . . Chen, Z. (2012). Advances in a fully integrated intravascular OCT-Ultrasound system for cardiovascular imaging. In J. Izatt, J. Fujimoto, & V. Tuchin (Eds.), OPTICAL COHERENCE TOMOGRAPHY AND COHERENCE DOMAIN OPTICAL METHODS IN BIOMEDICINE XVI Vol. 8213 (pp. 6 pages). San Francisco, CA: SPIE-INT SOC OPTICAL ENGINEERING. DOI |
| 2012 | Li, X., Li, J., Jing, J., Ma, T., Mohar, D., Raney, A., . . . Zhou, Q. (2012). Integrated IVUS-OCT Catheter for In Vivo Intravascular Imaging. In 2012 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IUS) (pp. 1564-1567). Dresden, GERMANY: IEEE. DOI |
1. 2018 – South Australia Photonics Catalyst Program grant
Funding amount $45,000; J. Li is the lead CI.
2. 2018 - Faculty of Health and Medical Sciences Research Infrastructure Funding Awards
Funding amount: $20,000.
3. 2018- ARC Centre of Excellence for Nanoscale BioPhotonics Small Equipment Grant
Funding amount: $5000; J.Li is the Lead CI.
4. 2017 - Faculty of Health and Medical Sciences Research Infrastructure Funding Awards
Funding amount $20,000; J. Li is the second CI of this proposal.
5. 2017 - Pilot Project Grant, Institute of Photonics and Advance Sensing (IPAS)
Funding amount $8,000; J. Li is the lead CI.
6. 2015 - Healy Research Collaboration award, Raine Medical research foundation
Funding amount $10,000; J. Li is the lead CI. This is a grant to support early career researcher to independently lead translational research.
| Institute | Year | Topic | |
|---|---|---|---|
| Guest Lecturer | Polytechnique Montreal | 2017 | Optical coherence tomography |
| Guest Lecturer | University of Southern California | 2013 | Optical coherence tomography |
Current Higher Degree by Research Supervision (University of Adelaide)
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2018 | Co-Supervisor | Fiber Imaging | Doctor of Philosophy | Doctorate | Full Time | Ms Lu Peng |
Other Supervision Activities
| Date | Role | Research Topic | Location | Program | Supervision Type | Student Load | Student Name |
|---|---|---|---|---|---|---|---|
| 2018 - ongoing | Co-Supervisor | High resolution microstructured optical fiber sensor | The University of Adelaide | — | Doctorate | — | Lu Peng |
Committee Memberships
| Date | Role | Committee | Institution | Country |
|---|---|---|---|---|
| 2018 - ongoing | Member | Technical Program Committee, 2019 Asia-Pacific Optical Sensors Conference (APOS) | 2019 Asia-Pacific Optical Sensors Conference | Australia |
| 2018 - ongoing | Member | Seminar Series Organising Committee, Faculty of Health and Medical Sciences | Faculty of Health and Medical Sciences | Australia |
| 2018 - ongoing | Member | Technical Program Committee of the AIP Congress with AOS Conference and ACOFT | Australian Optical Society | Australia |
| 2017 - ongoing | Member | IPAS Scientific Leadership Committee (SLC) | Institute for Photonics and Advanced Sensing | Australia |
| 2017 - ongoing | Chair | IPAS Science Network Committee | Institute for Photonics and Advanced Sensing | Australia |