Ms Jessica Williamson

NHMRC Grant-Funded Researcher A

School of Pharmacy and Biomedical Sciences

College of Health


I am a placental and pregnancy biologist working in reproductive and developmental health. After graduating with a PhD in 2026, I joined the One-Carbon Metabolism in Pregnancy and Disease Group as a postdoctoral researcher within the Robinson Research Institute and College of Health at Adelaide University.
 
My research examines how alterations in one-carbon metabolism influence placental function, maternal metabolic health, fetal development and offspring health. A major focus of my PhD was understanding the consequences of contemporary high folic acid (synthetic folate) exposure, arising from food fortification and supplement use, on maternal metabolic health and pregnancy outcome. Building on this work, my current research investigates the direct effects of folic acid exposure on fetal development, metabolic programming and longer-term offspring metabolic health. Through this research, I aim to establish when and how folic acid exposure influences fetal and offspring metabolic health and identify nutritional strategies that preserve the established benefits of folate and folic acid for fetal neurodevelopment while minimising potential metabolic harm to mothers and their babies.
 
More broadly, I am interested in the developmental origins of health and disease and the biological mechanisms through which exposure during pregnancy and early life shape lifelong health. I have extensive experience in in vitro models of placental development and function, including placental cell lines, explants and organoid cultures, and in vivo pregnancy models.
 
In my current role I supervise undergraduate and Honours students and co-supervise postgraduate research students.

Date Position Institution name
2026 - ongoing Postdoctoral Researcher Adelaide University

Date Institution name Country Title
2022 - 2026 Flinders University Australia Doctor of Philosophy
2021 The University of Adelaide Australia Bachelor of Health and Medical Science (Honours)
2018 - 2020 The University of Adelaide Australia Bachelor of Health and Medical Science (Advanced)

Year Citation
2026 Williamson, J. M., Arthurs, A. L., Smith, M. D., Leemaqz, S., Phillips-Hughes, A., McCullough, D., . . . Jankovic-Karasoulos, T. (2026). Excess folic acid disrupts placental endocrine function in vitro: a potential mechanism linking elevated folic acid exposure with gestational diabetes mellitus. Frontiers in Nutrition, 13, 12 pages.
DOI
2025 Arthurs, A. L., Dietrich, B., Knöfler, M., Lushington, C. J., Thomas, P. Q., Adikusuma, F., . . . Roberts, C. T. (2025). Genetically edited human placental organoids cast new light on the role of ACE2. Cell Death and Disease, 16(1), 78-1-78-12.
DOI Scopus3 WoS3 Europe PMC6
2025 Arthurs, A. L., Harrison, J. K., Williamson, J. M., & Roberts, C. T. (2025). Pregnancy and Birth Trends Across Australia, the United States of America and the United Kingdom. Journal of Clinical Medicine, 14(16), 5841-1-5841-18.
DOI WoS1 Europe PMC2
2025 Jankovic-Karasoulos, T., Smith, M. D., Leemaqz, S., Mittinty, M., Williamson, J., McCullough, D., . . . Roberts, C. T. (2025). Maternal Folate Excess, Placental Hormones, and Gestational Diabetes Mellitus: Findings from Prospective Cohorts Before and After Mandatory Folic Acid Food Fortification. Nutrients, 17(17), 2863-1-2863-16.
DOI Scopus4 WoS4 Europe PMC3
2023 Jankovic-Karasoulos, T., Smith, M. D., Leemaqz, S., Williamson, J., McCullough, D., Arthurs, A. L., . . . Roberts, C. T. (2023). Elevated Maternal Folate Status and Changes in Maternal Prolactin, Placental Lactogen and Placental Growth Hormone Following Folic Acid Food Fortification: Evidence from Two Prospective Pregnancy Cohorts. Nutrients, 15(7), 1553.
DOI Scopus11 WoS11 Europe PMC10
2023 Arthurs, A. L., McCullough, D., Williamson, J. M., Jankovic-Karasoulos, T., Smith, M. D., & Roberts, C. T. (2023). Factors influencing RNA yield from placenta tissue. Placenta, 140, 80-83.
DOI Scopus6 WoS6 Europe PMC7
2022 Williamson, J. M., Arthurs, A. L., Smith, M. D., Roberts, C. T., & Jankovic-Karasoulos, T. (2022). High Folate, Perturbed One-Carbon Metabolism and Gestational Diabetes Mellitus. Nutrients, 14(19), 1-24.
DOI Scopus53 WoS52 Europe PMC43

Year Citation
2025 Arthurs, A., Bhattacharjee, R., Smith, M., Medina, D., Menkhorst, E., Mora, G., . . . Roberts, C. (2025). Late-Onset Preeclampsia is characterised by Accelerated Placental Aging.
DOI

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