Jack Darby

Dr Jack Darby

Research Fellow

School of Pharmacy and Biomedical Science

College of Health

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.

Jack Darby is an early career researcher within the Early Origins of Adult Health Research Group at the University of South Australia. Jack’s research focuses on understanding the molecular mechanisms by which sub optimal in utero conditions such as fetal hypoxaemia and hypoglycaemia influence cardiac development and program adult onset cardiovascular disease. More recently he has been focussed on combining clinically translatable MRI measures with molecular techniques to test the effectiveness of intervention strategies that may reverse or prevent these detrimental molecular, morphological and functional changes from occurring in the fetal heart.  
Ultimately, Jack hopes to validate MRI techniques to measure fetal oxygenation, blood flow and cardiac function; so as to better inform clinicians about the health status of the intrauterine growth restricted (IUGR) fetus. In the long term the Early Origins of Adult Health Research group aim to develop an intervention strategy for IUGR fetuses so that every baby, no matter how small, has the best heart health in later life.

Year Citation
2025 Hammond, S. J., Roff, A. J., Robinson, J. L., Darby, J. R. T., Meakin, A. S., Clifton, V. L., . . . Gatford, K. L. (2025). In utero exposure to experimental maternal asthma alters fetal airway development in sheep. Experimental Physiology, 110(6), 899-907.
DOI Scopus2 WoS2 Europe PMC3
2025 Roff, A. J., Davies, A. N., Clifton, V. L., Stark, M. J., Tai, A., Robinson, J. L., . . . Gatford, K. L. (2025). Pregnancy does not affect progression of mild experimental asthma in sheep. The Journal of Physiology, 603(5), 1241-1261.
DOI Scopus2 WoS2 Europe PMC2
2025 Bertossa, M. R., Darby, J. R. T., Holman, S. L., Cho, S. K. S., Meakin, A. S., Lock, M. C., . . . Morrison, J. L. (2025). Fetal glucose availability: a key regulator of the metabolic, hormonal and contractility profiles of the fetal sheep heart. Journal of Physiology, 23 pages.
DOI
2025 Cho, S. K. S., Darby, J. R. T., Williams, G. K., Holman, S. L., Rai, A., Van Amerom, J. F. P., . . . Seed, M. (2025). Post-myocardial infarction remodeling and hyperkinetic remote myocardium in sheep measured by cardiac MRI feature tracking. Journal of Magnetic Resonance Imaging, 61(3), 1323-1335.
DOI Scopus2 Europe PMC2
2025 Flouri, D., Darby, J. R. T., Holman, S. L., Williams, G., Vavourakis, V., David, A. L., . . . Melbourne, A. (2025). Feasibility of multimodal magnetic resonance imaging to assess maternal hyperoxygenation in sheep pregnancy. The Journal of Physiology, 603(5), 1029-1044.
DOI
2024 Cho, S. K. S., Darby, J. R. T., Saini, B. S., Holman, S. L., Lock, M. C., Perumal, S. R., . . . Morrison, J. L. (2024). Late-gestation maternal undernutrition induces circulatory redistribution while preserving uteroplacental function independent of fetal glycaemic state. Journal of Physiology, 602(24), 7065-7083.
DOI Scopus3 WoS2 Europe PMC3
2024 Darby, J. R. T., Flouri, D., Cho, S. K. S., Williams, G. K., Holman, S. L., Meakin, A. S., . . . Morrison, J. L. (2024). Maternal tadalafil treatment does not increase uterine artery blood flow or oxygen delivery in the pregnant ewe. Experimental Physiology, 109(6), 980-991.
DOI Scopus2 WoS2 Europe PMC3
2024 Bertossa, M. R., Darby, J. R. T., Holman, S. L., Meakin, A. S., Li, C., Huber, H. F., . . . Morrison, J. L. (2024). Maternal high fat–high energy diet alters metabolic factors in the non-human primate fetal heart. Journal of Physiology, 602(17), 4251-4269.
DOI Scopus5 WoS4 Europe PMC3
2024 Dimasi, C. G., Darby, J. R. T., Holman, S. L., Quinn, M., Meakin, A. S., Seed, M., . . . Morrison, J. L. (2024). Cardiac growth patterns and metabolism before and after birth in swine: Role of miR in proliferation, hypertrophy and metabolism. Journal of Molecular and Cellular Cardiology Plus, 9(100084), 14 pages.
DOI Scopus4 WoS4 Europe PMC4
2024 Dimasi, C. G., Darby, J. R. T., Cho, S. K. S., Saini, B. S., Holman, S. L., Meakin, A. S., . . . Morrison, J. L. (2024). Reduced in utero substrate supply decreases mitochondrial abundance and alters the expression of metabolic signalling molecules in the fetal sheep heart. Journal of Physiology, 602(21), 5901-5922.
DOI Scopus16 WoS17 Europe PMC15
2024 Kühle, H., Cho, S. K. S., Charest Pekeski, A. J., Chow, J. S. M., Lee, F. T., Aujla, T., . . . Haller, C. (2024). Echocardiographic assessment of cardiovascular physiology of preterm miniature piglets supported with a pumped artificial placenta system. Prenatal Diagnosis, 44(6-7), 888-898.
DOI Scopus1 Europe PMC1
2024 Holmes, H., Saini, B. S., Moir, O. J., Darby, J. R. T., Morrison, J. L., Sun, L., & Seed, M. (2024). Pulmonary vascular regulation in the fetal and transitional lung. Clinics in Perinatology, 51(1), 1-19.
DOI Scopus1
2024 Darby, J. R. T., Saini, B. S., Holman, S. L., Hammond, S. J., Perumal, S. R., Macgowan, C. K., . . . Morrison, J. L. (2024). Acute-on-chronic: using magnetic resonance imaging to disentangle the haemodynamic responses to acute and chronic fetal hypoxaemia. Frontiers in Medicine, 11, 1340012-1-1340012-14.
DOI WoS1
2024 Robinson, J. L., Roff, A. J., Hammond, S. J., Darby, J. R. T., Meakin, A. S., Holman, S. L., . . . Gatford, K. L. (2024). Betamethasone improved near-term neonatal lamb lung maturation in experimental maternal asthma. Experimental Physiology, 109(11), 1967-1979.
DOI Scopus4 WoS4 Europe PMC6
2023 Saini, B. S., Ducas, R., Darby, J. R. T., Marini, D., Sun, L., Macgowan, C. K., . . . Seed, M. (2023). Feasibility of MRI assessment of maternal-fetal oxygen transport and consumption relative to maternal position in healthy late gestational pregnancies. Journal of Physiology, 601(23), 5413-5436.
DOI Scopus4 Europe PMC4
2023 Kühle, H., Cho, S. K. S., Barber, N., Goolaub, D. S., Darby, J. R. T., Morrison, J. L., . . . Seed, M. (2023). Advanced imaging of fetal cardiac function. Frontiers in Cardiovascular Medicine, 10(1206138), 1-16.
DOI Scopus13 Europe PMC13
2023 Meakin, A. S., Amirmostofian, M., Darby, J. R., Holman, S. L., Morrison, J. L., & Wiese, M. D. (2023). Characterisation of cytochrome P450 isoenzyme activity in sheep liver and placental microsomes. Placenta, 131, 82-89.
DOI Scopus3 WoS3 Europe PMC2
2023 Paramasivan, S., Morrison, J. L., Lock, M. C., Darby, J. R. T., Barrero, R. A., Mills, P. C., & Sadowski, P. (2023). Automated proteomics workflows for high-throughput library generation and biomarker detection using data-independent acquisition. Journal of proteome research, 22(6), 2018-2029.
DOI Scopus7 WoS7 Europe PMC6
2023 Darby, J. R. T., Zhang, S., Holman, S. L., Muhlhausler, B. S., McMillen, I. C., & Morrison, J. L. (2023). Cardiac growth and metabolism of the fetal sheep are not vulnerable to a 10 day increase in fetal glucose and insulin concentrations during late gestation. Heliyon, 9(7), e18292-1-e18292-14.
DOI Scopus5 WoS5 Europe PMC5
2023 Dimasi, C. G., Darby, J. R. T., & Morrison, J. L. (2023). A change of heart: understanding the mechanisms regulating cardiac proliferation and metabolism before and after birth. Journal of Physiology, 601(8), 1319-1341.
DOI
2023 Darby, J. R. T., Williams, G. K., Cho, S. K. S., Meakin, A. S., Holman, S. L., Quinn, M., . . . Morrison, J. L. (2023). Acute resveratrol exposure does not impact hemodynamics of the fetal sheep. Physiological Reports, 11(12), 12 pages.
DOI Scopus5 WoS5 Europe PMC5
2022 Morrison, J. L., Williams, G. K., Cho, S. K. S., Saini, B. S., Meakin, A. S., Holman, S. L., . . . Darby, J. R. T. (2022). MRI Characterization of Blood Flow and Oxygen Delivery in the Fetal Sheep whilst Exposed to Sildenafil Citrate. Neonatology, 119(6), 735-744.
DOI Scopus8 WoS8 Europe PMC8
2022 Darby, J. R. T., Chiu, J., Regnault, T. R. H., & Morrison, J. L. (2022). Placental insufficiency induces a sexually dimorphic response in the expression of cardiac growth and metabolic signalling molecules upon exposure to a postnatal western diet in guinea pigs. Journal of Developmental Origins of Health and Disease, 13(3), 345-357.
DOI
2022 Flouri, D., Darby, J. R. T., Holman, S. L., Cho, S. K. S., Dimasi, C. G., Perumal, S. R., . . . Morrison, J. L. (2022). Placental MRI predicts fetal oxygenation and growth rates in sheep and human pregnancy. Advanced Science, 9(30, article no. 2203738), 1-14.
DOI
2022 Meakin, A. S., Darby, J. R. T., Holman, S. L., Wiese, M. D., & Morrison, J. L. (2022). Maternal-placental-fetal drug metabolism is altered by late gestation undernutrition in the pregnant ewe. Life Sciences, 298(article no. 120521), 1-9.
DOI Scopus15 WoS13 Europe PMC8
2022 Dimasi, C. G., & Darby, J. R. T. (2022). Does the growth restricted fetal heart burn less fat?. Journal of Physiology, 600(7), 1585-1586.
DOI
2022 Charest Pekeski, A. J., Cho, S. K. S., Aujla, T., Sun, L., Quinn, M., Darby, J. R. T., . . . Haller, C. (2022). Impact of the addition of a centrifugal pump in a preterm miniature pig model of the artificial placenta. Frontiers in Physiology, 13(article number 925772), 1-17.
DOI Scopus12 Europe PMC11
2022 Zhang, W. Q., Sorvina, A., Morrison, J. L., Darby, J. R. T., Brooks, D. A., Plush, S. E., & Afshar Vahid, S. (2022). Development of an optical fiber-based redox monitoring system for tissue metabolism. Journal of Biophotonics, 15(4, article no, e202100304), 1-11.
DOI Scopus2 WoS2 Europe PMC1
2022 Robinson, J. L., & Darby, J. R. T. (2022). Something worth waiting for: is delayed cord clamping always beneficial?. Journal of Physiology, 600(16), 3641-3642.
DOI
2022 Hammond, S. J., & Darby, J. R. T. (2022). A no brainer: Intervening early to protect against perinatal brain injury.. J Physiol, 600(18), 4059-4061.
DOI
2022 Wiese, M. D., Berry, M. J., Hissaria, P., Darby, J. R. T., & Morrison, J. L. (2022). COVID-19: Can we treat the mother without harming her baby?. Journal of Developmental Origins of Health and Disease, 13(1), 9-19.
DOI Scopus6 WoS5 Europe PMC5
2021 Meakin, A. S., Cuffe, J. S. M., Darby, J. R. T., Morrison, J. L., & Clifton, V. L. (2021). Let’s talk about placental sex, baby: Understanding mechanisms that drive female-and male-specific fetal growth and developmental outcomes. International Journal of Molecular Sciences, 22(12), 6386-1-6386-17.
DOI Scopus112 WoS107 Europe PMC103
2021 Dimasi, C. G., Lazniewska, J., Plush, S. E., Saini, B. S., Holman, S. L., Cho, S. K. S., . . . Darby, J. R. T. (2021). Redox ratio in the left ventricle of the growth restricted fetus is positively correlated with cardiac output. Journal of Biophotonics, 14(12, article no. e202100157), 1-13.
DOI Scopus16 WoS16 Europe PMC15
2021 McBride, G. M., Meakin, A. S., Soo, J. Y., Darby, J. R. T., Varcoe, T. J., Bradshaw, E. L., . . . Morrison, J. L. (2021). Intrauterine growth restriction alters the activity of drug metabolising enzymes in the maternal-placental-fetal unit. Life Sciences, 285(120016), 1-9.
DOI Scopus21 WoS20 Europe PMC16
2021 Wiese, M. D., Meakin, A. S., Varcoe, T. J., Darby, J. R. T., Sarr, O., Kiser, P., . . . Morrison, J. L. (2021). Hepatic cytochrome P450 function is reduced by life-long Western diet consumption in guinea pig independent of birth weight. Life Sciences, 287(120133), 120133-1-120133-11.
DOI Scopus8 WoS8 Europe PMC5
2021 Padhee, M., McMillen, C., Zhang, S., Armitage, J. A., Head, G. A., MacLaughlin, S. M., . . . Morrison, J. L. (2021). Impact of in vitro embryo culture and transfer on blood pressure regulation in the adolescent lamb. Journal of Developmental Origins of Health and Disease, 12(5), 731-737.
DOI Scopus3 WoS3 Europe PMC3
2021 Darby, J. R. T., Varcoe, T. J., Holman, S. L., McMillen, I. C., & Morrison, J. L. (2021). The reliance on α‐adrenergic receptor stimuli for blood pressure regulation in the chronically hypoxaemic fetus is not dependent on post‐ganglionic activation. The Journal of Physiology, 599(4), 1307-1318.
DOI Scopus10 WoS10 Europe PMC7
2021 Lazniewska, J., Darby, J. R. T., Holman, S. L., Sorvina, A., Plush, S. E., Massi, M., . . . Morrison, J. L. (2021). In utero substrate restriction by placental insufficiency or maternal undernutrition decreases optical redox ratio in foetal perirenal fat. Journal of Biophotonics, 14(4), e202000322-1-e202000322-13.
DOI Scopus4 WoS3 Europe PMC2
2021 Ren, J., Lock, M. C., Darby, J. R. T., Orgeig, S., Holman, S. L., Quinn, M., . . . Morrison, J. L. (2021). PPARγ activation in late gestation does not promote surfactant maturation in the fetal sheep lung. Journal of Developmental Origins of Health and Disease, 12(6), 963-974.
DOI Scopus4 WoS12 Europe PMC3
2021 Charest Pekeski, A. J., Sheta, A., Taniguchi, L., McVey, M. J., Aujla, T., Cho, S. K. S., . . . Haller, C. (2021). Achieving sustained extrauterine life: challenges of an artificial placenta in fetal pigs as a model of the preterm human fetus. Physiological Reports, 9(5, article number e14742), 1-20.
DOI Scopus27 Europe PMC19
2021 Ren, J., Darby, J. R. T., Lock, M. C., Holman, S. L., Saini, B. S., Bradshaw, E. L., . . . Morrison, J. L. (2021). Impact of maternal late gestation undernutrition on surfactant maturation, pulmonary blood flow and oxygen delivery measured by magnetic resonance imaging in the sheep fetus. Journal of Physiology, 599(20), 4705-4724.
DOI Scopus11 WoS8 Europe PMC8
2021 Schrauben, E. M., Darby, J. R. T., Berry, M. J., Saini, B. S., Quinn, M., Holman, S. L., . . . Morrison, J. L. (2021). Open or closed: Changes in ductus arteriosus flow patterns at birth using 4D flow MRI in newborn piglets. Physiological Reports, 9(17), 15 pages.
DOI Scopus5 WoS5 Europe PMC6
2021 Saini, B. S., Darby, J. R. T., Marini, D., Portnoy, S., Lock, M. C., Soo, J. Y., . . . Seed, M. (2021). An MRI approach to assess placental function in healthy humans and sheep. The Journal of Physiology, 599(10), 2573-2602.
DOI Scopus26 WoS23 Europe PMC24
2021 Aujla, T., Darby, J. R. T., Saini, B. S., Lock, M. C., Holman, S. L., Bradshaw, E. L., . . . Morrison, J. L. (2021). Impact of resveratrol-mediated increase in uterine artery blood flow on fetal haemodynamics, blood pressure and oxygenation in sheep. Experimental Physiology, 106(5), 1166-1180.
DOI Scopus9 WoS9 Europe PMC9
2021 Morrison, J. L., Darby, J. R. T., & Michael, N. (2021). Themed issue on the DOHaD workshop on fetal, placental and pediatric imaging. Journal of Developmental Origins of Health and Disease, 12(2), 151-152.
DOI
2021 Flouri, D., Darby, J. R. T., Holman, S. L., Perumal, S. R., David, A. L., Morrison, J. L., & Melbourne, A. (2021). Magnetic resonance imaging of placentome development in the pregnant ewe. Placenta, 105, 61-69.
DOI
2021 Darby, J. R. T., Berry, M. J., Quinn, M., Holman, S. L., Bradshaw, E. L., Jesse, S. M., . . . Morrison, J. L. (2021). Haemodynamics and cerebral oxygenation of neonatal piglets in the immediate ex utero period supported by mechanical ventilation or ex utero oxygenator. Journal of Physiology, 599(10), 2751-2761.
DOI
2020 Schrauben, E. M., Darby, J. R. T., Saini, B. S., Holman, S. L., Lock, M. C., Perumal, S. R., . . . Macgowan, C. K. (2020). Technique for comprehensive fetal hepatic blood flow assessment in sheep using 4D flow MRI. Journal of Physiology, 598(17), 3555-3567.
DOI Scopus9 WoS9 Europe PMC9
2020 Darby, J. R. T., Schrauben, E. M., Saini, B. S., Holman, S. L., Rajan Perumal, S., Seed, M., . . . Morrison, J. L. (2020). Umbilical vein infusion of Prostaglandin I2 increases ductus venosus shunting of oxygen rich blood but does not increase cerebral oxygen delivery in the fetal sheep. The Journal of Physiology, 598(21), 4957-4967.
DOI
2020 Cho, S. K. S., Darby, J. T. R., Saini, B. S., Lock, M. C., Holman, S. L., Lim, J. M., . . . Seed, M. (2020). Feasibility of ventricular volumetry by cardiovascular MRI to assess cardiac function in the fetal sheep. The Journal of Physiology, 598(13), 2557-2573.
DOI Scopus24 WoS22 Europe PMC20
2020 Saini, B. S., Darby, J. R. T., Portnoy, S., Sun, L., van Amerom, J., Lock, M. C., . . . Seed, M. (2020). Normal human and sheep fetal vessel oxygen saturations by T2 magnetic resonance imaging. The Journal of Physiology, 598(15), 3259-3281.
DOI Scopus59 WoS53 Europe PMC49
2020 Darby, J. R. T., Sorvina, A., Bader, C. A., Lock, M. C., Soo, J. Y., Holman, S. L., . . . Morrison, J. L. (2020). Detecting metabolic differences in fetal and adult sheep adipose and skeletal muscle tissues. Journal of Biophotonics, 13(3), e201960085-1-e201960085-13.
DOI Scopus16 WoS17 Europe PMC14
2020 Lock, M. C., Tellam, R. L., Darby, J. R. T., Soo, J. Y., Brooks, D. A., Macgowan, C. K., . . . Morrison, J. L. (2020). Differential gene responses 3 days following infarction in the fetal and adolescent sheep heart. Physiological Genomics, 52(3), 143-159.
DOI Scopus6 WoS5 Europe PMC4
2020 Varcoe, T. J., Darby, J. R. T., Holman, S. L., Bradshaw, E. L., Kuchel, T., Vaughan, L., . . . Morrison, J. L. (2020). Fetal cardiovascular response to acute hypoxia during maternal anesthesia. Physiological reports, 8(3), e14365.
DOI Scopus14 Europe PMC12
2020 Darby, J. R. T., Varcoe, T. J., Orgeig, S., & Morrison, J. L. (2020). Cardiorespiratory consequences of intrauterine growth restriction: influence of timing, severity and duration of hypoxaemia. Theriogenology, 150, 84-95.
DOI Scopus54 WoS49 Europe PMC40
2020 Lock, M. C., Tellam, R. L., Darby, J. R. T., Soo, J. Y., Brooks, D. A., Seed, M., . . . Morrison, J. L. (2020). Identification of novel miRNAs involved in cardiac repair following infarction in fetal and adolescent sheep hearts. Frontiers in Physiology, 11(article no. 614), 614-1-614-21.
DOI Scopus9 WoS9 Europe PMC8
2020 McBride, G. M., Wiese, M. D., Soo, J. Y., Darby, J. R., Berry, M. J., Varcoe, T. J., & Morrison, J. L. (2020). The impact of intrauterine growth restriction on cytochrome P450 enzyme expression and activity. Placenta, 99, 50-62.
DOI Scopus12 WoS12 Europe PMC8
2020 Morrison, J. L., Ayonrinde, O. T., Care, A. S., Clarke, G. D., Darby, J. R. T., David, A. L., . . . Velan, S. S. (2020). Seeing the fetus from a DOHaD perspective: Discussion paper from the advanced imaging techniques of DOHaD applications workshop held at the 2019 DOHaD World Congress. Journal of Developmental Origins of Health and Disease, 12(2), 1-15.
DOI Scopus6 WoS5 Europe PMC4
2019 Lock, M. C., Darby, J. R. T., Soo, J. Y., Brooks, D. A., Perumal, S. R., Selvanayagam, J. B., . . . Morrison, J. L. (2019). Differential response to injury in fetal and adolescent sheep hearts in the immediate post in the immediate post-myocardial myocardial myocardial infarction period. Frontiers in Physiology, 10(208), 208-1-208-24.
DOI Scopus31 WoS32 Europe PMC31
2019 Varcoe, T. J., Darby, J. R. T., Gatford, K. L., Holman, S. L., Cheung, P., Berry, M. J., . . . Morrison, J. L. (2019). Considerations in selecting postoperative analgesia for pregnant sheep following fetal instrumentation surgery. Animal Frontiers, 9(3), 60-67.
DOI Scopus34 WoS32 Europe PMC28
2019 Darby, J. R. T., Saini, B. S., Soo, J. Y., Lock, M. C., Holman, S. L., Bradshaw, E. L., . . . Morrison, J. L. (2019). Subcutaneous maternal resveratrol treatment increases uterine artery blood flow in the pregnant ewe and increases fetal but not cardiac growth. The journal of physiology, 597(20), 5063-5077.
DOI Scopus40 WoS39 Europe PMC34
2019 Berry, M. J., Darby, J. R. T., O'Byrne, D. M., Dyson, R. M., Sixtus, R., Holman, S. L., . . . Morrison, J. L. (2019). Arginine Vasopressin improves cerebral perfusion following controlled haemorrhage in adult ewes. The journal of physiology, 597(16), 4165-4173.
DOI
2019 Duan, A. Q., Darby, J. R. T., Soo, J. Y., Lock, M. C., Zhu, M. Y., Flynn, L. V., . . . Seed, M. (2019). Feasibility of phase-contrast cine magnetic resonance imaging for measuring blood flow in the sheep fetus. American journal of physiology - Regulatory integrative and comparative physiology, 317(6), R780-R792.
DOI Scopus36 WoS36 Europe PMC25
2019 Darby, J. R. T., & Morrison, J. L. (2019). And the beat goes on.... Journal of physiology, 596(21), 5073-5074.
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2019 Schrauben, E. M., Saini, B. S., Darby, J. R. T., Soo, J. Y., Lock, M. C., Stirrat, E., . . . MacGowan, C. K. (2019). Fetal hemodynamics and cardiac streaming assessed by 4D flow cardiovascular magnetic resonance in fetal sheep. Journal of cardiovascular magnetic resonance, 21(article no 8), 1-11.
DOI Scopus51 WoS53 Europe PMC48
2019 Darby, J. R. T., Mohd Dollah, M. H. B., Regnault, T. R. H., Williams, M. T., & Morrison, J. L. (2019). Systematic review: impact of resveratrol exposure during pregnancy on maternal and fetal outcomes in animal models of human pregnancy complications-are we ready for the clinic?. Pharmacological research, 144, 264-278.
DOI Scopus37 WoS36 Europe PMC27
2018 Darby, J. R. T., McMillen, I. C., & Morrison, J. L. (2018). Maternal undernutrition in late gestation increases IGF2 signalling molecules and collagen deposition in the right ventricle of the fetal sheep heart. Journal of physiology, 596(12), 2345-2358.
DOI
2018 Morrison, J., Sorvina, A., Darby, J., Bader, C., Lock, M., Seed, M., . . . Brooks, D. (2018). Label-free imaging of redox status and collagen deposition showing metabolic differences in the heart. Journal of Biophotonics, 11(3), e20170024-12-e201700242-7.
DOI Scopus5 WoS6 Europe PMC4
2018 Morrison, J., Botting, K., Darby, J., David, A., Dyson, R., Gatford, K., . . . Berry, M. (2018). Guinea pig models for translation of the developmental origins of health and disease hypothesis into the clinic. The Journal of Physiology, 596(23), 5535-5569.
DOI Scopus116 WoS113 Europe PMC116
2018 Sorvina, A., Bader, C. A., Darby, J. R. T., Lock, M. C., Soo, J. Y., Johnson, I. R. D., . . . Brooks, D. A. (2018). Mitochondrial imaging in live or fixed tissues using a luminescent iridium complex. Scientific Reports, 8(1, article no. 8191), 8191-1-8191-8.
DOI Scopus33 WoS29 Europe PMC22
2018 Morrison, J. L., Berry, M. J., Botting, K. J., Darby, J. R., Frasch, M. G., Gatford, K. L., . . . Tellam, R. L. (2018). Improving pregnancy outcomes in humans through studies in sheep. American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 315(6), 1123-1153.
DOI Scopus148 WoS141 Europe PMC129
2017 Duan, A. Q., Lock, M. C., Perumal, S. R., Darby, J. R., Soo, J. Y., Selvanayagam, J. B., . . . Morrison, J. L. (2017). Feasibility of detecting myocardial infarction in the sheep fetus using late gadolinium enhancement CMR imaging. Journal of cardiovascular magnetic resonance, 19(1, article no, 69), 1-11.
DOI Scopus35 WoS32 Europe PMC31
2017 Darby, J., McMillen, C., & Morrison, J. (2017). Maternal undernutrition increases fibrosis in the late gestation fetal heart. Heart, Lung and Circulation, 26(S2), 107.
DOI
2016 Lock, M., Tellam, R., Porrello, E., Soo, J., Darby, J., Brooks, D., & Morrison, J. (2016). miR-133a and target gene expression in the foetus and 6 month old sheep heart in response to myocardial infarction. Heart, lung and circulation, 25(S2), 117.
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2015 Darby, J., Zhang, S., McMillen, I., Mühlhausler, B., & Morrison, J. (2015). Late gestation over nutrition alters the cardiac metabolic profile. Heart, Lung and Circulation, 24(S3), S189.
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Year Citation
2023 Roff, A. J., Robinson, J. L., Hammond, S. J., Davies, A., Clifton, V. L., Wallace, M. J., . . . Donnelley, M. (2023). X-ray Velocimetry Detects Changes in Local Airflow in a Sheep Model of Asthma During Pregnancy. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. Germany: SPRINGER HEIDELBERG.
2023 Darby, J. R. T., Flouri, D., Cho, S. K. S., Williams, G. K., Holman, S. L., Macgowan, C. K., . . . Morrison, J. L. (2023). Maternal tadalafil treatment does not increase uterine artery blood flow or oxygen delivery in the pregnant ewe. Poster session presented at the meeting of Reproductive Sciences. Germany: Springer.
2023 Sarah, H. J., Ahdi, N., Darby, J. R. T., Holman, S. L., Saini, B. S., Macgowan, C. K., . . . Davidson, J. O. (2023). Does low oxygen availability affect oligodendrocyte density in the brain of the growth restricted fetus?. Poster session presented at the meeting of Reproductive Sciences. Germany: Springer.
2023 Bertossa, M. R., Darby, J. R. T., Holman, S. L., Cho, S. K., Macgowan, C. K., Seed, M., & Morrison, J. L. (2023). The impact of maternal undernutrition in late gestation on fetal cardiac remodelling in sheep. Poster session presented at the meeting of Reproductive Sciences. Germany: Springer.
2023 Minns, A., Holman, S. L., Darby, J. R. T., & Morrison, J. L. (2023). The role of endothelial nitric oxide in fetal baroreflex sensitivity in a pregnant sheep model of late gestation undernutrition. Poster session presented at the meeting of Reproductive Sciences. Germany: Springer.
2023 Dimasi, C. G., Darby, J. R. T., Holman, S., Quinn, M., Bradshaw, E. L., Jesse, S. M., & Morrison, J. L. (2023). Developmental origins of cardiac disease: understanding cardiac maturation in pigs. Poster session presented at the meeting of Reproductive Sciences. Germany: Springer.

Date Role Research Topic Program Degree Type Student Load Student Name
2022 Co-Supervisor - Doctor of Philosophy Doctorate Full Time Miss Melanie Bertossa
2022 Co-Supervisor - Doctor of Philosophy Doctorate Full Time Miss Sarah Jane Hammond
2022 Co-Supervisor - Doctor of Philosophy Doctorate Full Time Mr Jordan Minns

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