Imre Kouw

Dr Imre Kouw

Ext-Funded Research Fellow (B)

Adelaide Medical School

Faculty of Health and Medical Sciences


Dr Imre Kouw, BSc Dietetics and MSc Nutrition, is Postdoctoral Research Fellow at the RAH ICU Research Group. Imre completed her PhD in 2018 at Maastricht University under supervision of Professor Luc van Loon, which focussed on nutritional strategies to attenuate muscle loss during hospitalization in older and clinical populations. During her PhD, she gained extensive experience in stable isotope tracer methodology to assess muscle protein metabolism. She conducted multiple nutritional intervention trials in healthy older volunteers and clinical populations (patients with frailty, Type 2 Diabetes, elective hip or knee replacement, or hip fracture surgery and those prior to bariatric surgery). Imre has been awarded multiple research awards during her PhD including the European Society for Clinical Nutrition and Metabolism Best Oral Presentation (2016) and Gatorade Sport Science Institute (2016) Nutrition Award, and more recently a price for Best PhD Thesis 2019 in Clinical Nutrition and Metabolism (Dutch Nutrition Society for Clinical Nutrition and Metabolism) and the British Nutrition Foundation Drummond Early Career Scientist Award (2020). Imre received an ESPEN Research Fellowship (2019) to investigate the effect of intermittent fasting on muscle protein metabolism in overweight and obese middle-aged men at the Exercise and Nutrition Research Program at Australian Catholic University in Melbourne and apply a novel tracer methodology, deuterated water. Imre recently joined the RAH ICU Research Group in July 2020 where she will continue her postdoctoral training on muscle protein metabolism in Intensive Care Unit patients, she recently received a prestigious Rubicon Fellowship (2020-2022) from the Netherlands Organisation for Health Research and Development NOW/ZonMW. Imre has previous (co-)supervisory experience with BSc, MSc, and PhD students.

  • Journals

    Year Citation
    2022 Bland, K. A., Kouw, I. W. K., van Loon, L. J. C., Zopf, E. M., & Fairman, C. M. (2022). Exercise-Based Interventions to Counteract Skeletal Muscle Mass Loss in People with Cancer: Can We Overcome the Odds?. Sports Medicine, 52(5), 1009-1027.
    DOI Scopus2 WoS3
    2022 Weijzen, M. E. G., Van Gassel, R. J. J., Kouw, I. W. K., Trommelen, J., Gorissen, S. H. M., Van Kranenburg, J., . . . Van Loon, L. J. C. (2022). Ingestion of Free Amino Acids Compared with an Equivalent Amount of Intact Protein Results in More Rapid Amino Acid Absorption and Greater Postprandial Plasma Amino Acid Availability Without Affecting Muscle Protein Synthesis Rates in Young Adults in a Double-Blind Randomized Trial. Journal of Nutrition, 152(1), 59-67.
    DOI Scopus4 WoS5 Europe PMC1
    2022 Chapple, L. -A. S., Kouw, I. W. K., Summers, M. J., Weinel, L. M., Gluck, S., Raith, E., . . . Chapman, M. J. (2022). Muscle Protein Synthesis Following Protein Administration in Critical Illness.. American journal of respiratory and critical care medicine.
    DOI
    2022 Kouw, I. W. K., Heilbronn, L. K., & van Zanten, A. R. H. (2022). Intermittent feeding and circadian rhythm in critical illness. Current Opinion in Critical Care, 28(4), 381-388.
    DOI
    2021 Pinckaers, P. J. M., Kouw, I. W. K., Hendriks, F. K., Van Kranenburg, J. M. X., De Groot, L. C. P. G. M., Verdijk, L. B., . . . Van Loon, L. J. C. (2021). No differences in muscle protein synthesis rates following ingestion of wheat protein, milk protein, and their protein blend in healthy, young males. British Journal of Nutrition, 126(12), 1832-1842.
    DOI Scopus13 WoS13 Europe PMC6
    2021 Chapple, L. A. S., Dirks, M. L., & Kouw, I. W. K. (2021). Stable isotope approaches to study muscle mass outcomes in clinical populations. Clinical Nutrition Open Science, 36, 98-108.
    DOI Scopus1
    2021 Holwerda, A. M., Trommelen, J., Kouw, I. W. K., Senden, J. M., Goessens, J. P. B., Van Kranenburg, J., . . . Van Loon, L. J. C. (2021). Exercise plus presleep protein ingestion increases overnight muscle connective tissue protein synthesis rates in healthy older men. International Journal of Sport Nutrition and Exercise Metabolism, 31(3), 217-226.
    DOI Scopus1 WoS3
    2021 Kouw, I. W. K., Pinckaers, P. J. M., Le Bourgot, C., Van Kranenburg, J. M. X., Zorenc, A. H., De Groot, L. C. P. G. M., . . . Van Loon, L. J. C. (2021). Ingestion of an ample amount of meat substitute based upon a lysine-enriched, plant-based protein blend stimulates postprandial muscle protein synthesis to a similar extent as an isonitrogenous amount of chicken in healthy, young men. British Journal of Nutrition, 11 pages.
    DOI Scopus2 WoS1
    2020 Fuchs, C. J., Kouw, I. W. K., Churchward-Venne, T. A., Smeets, J. S. J., Senden, J. M., van Marken Lichtenbelt, W. D., . . . van Loon, L. J. C. (2020). Postexercise cooling impairs muscle protein synthesis rates in recreational athletes. Journal of Physiology, 598(4), 755-772.
    DOI Scopus27 WoS23 Europe PMC14
    2020 Weijzen, M. E. G., Kouw, I. W. K., Geerlings, P., Verdijk, L. B., & van Loon, L. J. C. (2020). During Hospitalization, Older Patients at Risk for Malnutrition Consume <0.65 Grams of Protein per Kilogram Body Weight per Day.. Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition, 35(4), 655-663.
    DOI Scopus7 WoS4 Europe PMC3
    2020 Gonzalez, J., Dirks, M. L., Holwerda, A. M., Kouw, I. W., & van Loon, L. J. C. (2020). Intermittent versus continuous enteral nutrition attenuates increases in insulin and leptin during short-term bed rest.. European Journal of Applied Physiology, 120(9), 2083-2094.
    DOI Scopus4 WoS4
    2020 Gorissen, S. H. M., Trommelen, J., Kouw, I. W. K., Holwerda, A. M., Pennings, B., Groen, B. B. L., . . . van Loon, L. J. C. (2020). Protein Type, Protein Dose, and Age Modulate Dietary Protein Digestion and Phenylalanine Absorption Kinetics and Plasma Phenylalanine Availability in Humans. The Journal of nutrition, 150(8), 2041-2050.
    DOI Scopus33 WoS33 Europe PMC14
    2019 Kouw, I. W. K., Van Dijk, J. W., Horstman, A. M. H., Kramer, I. F., Goessens, J. P. B., Van Dielen, F. M. H., . . . Van Loon, L. J. C. (2019). Basal and postprandial myofibrillar protein synthesis rates do not differ between lean and obese middle-Aged men. Journal of Nutrition, 149(9), 1533-1542.
    DOI Scopus12 WoS13 Europe PMC6
    2019 Snijders, T., Trommelen, J., Kouw, I. W. K., Holwerda, A. M., Verdijk, L. B., & van Loon, L. J. C. (2019). The impact of pre-sleep protein ingestion on the skeletal muscle adaptive response to exercise in humans: An update. Frontiers in Nutrition, 6, 8 pages.
    DOI Scopus28 WoS33 Europe PMC20
    2019 Dirks, M. L., Smeets, J. S. J., Holwerda, A. M., Kouw, I. W. K., Marzuca-Nassr, G. N., Gijsen, A. P., . . . van Loon, L. J. C. (2019). Dietary feeding pattern does not modulate the loss of muscle mass or the decline in metabolic health during short-term bed rest. American Journal of Physiology - Endocrinology and Metabolism, 316(3), E536-E545.
    DOI Scopus17 WoS17 Europe PMC5
    2019 Horstman, A. M. H., Kouw, I. W. K., Van Dijk, J. W., Hamer, H. M., Groen, B. B. L., Van Kranenburg, J., . . . Van Loon, L. J. C. (2019). The muscle protein synthetic response to whey protein ingestion is greater in middle-aged women compared with men. Journal of Clinical Endocrinology and Metabolism, 104(4), 994-1004.
    DOI Scopus6 WoS6 Europe PMC3
    2019 Weijzen, M. E. G., Kouw, I. W. K., Verschuren, A. A. J., Muyters, R., Geurts, J. A., Emans, P. J., . . . van Loon, L. J. C. (2019). Protein Intake Falls below 0.6 g·kg <sup>-1</sup> ·d <sup>-1</sup> in Healthy, Older Patients Admitted for Elective Hip or Knee Arthroplasty. Journal of Nutrition, Health and Aging, 23(3), 299-305.
    DOI Scopus8 WoS7 Europe PMC3
    2019 Kouw, I. W. K., Groen, B. B. L., Smeets, J. S. J., Kramer, I. F., van Kranenburg, J. M. X., Nilwik, R., . . . Verdijk, L. B. (2019). One Week of Hospitalization Following Elective Hip Surgery Induces Substantial Muscle Atrophy in Older Patients. Journal of the American Medical Directors Association, 20(1), 35-42.
    DOI Scopus30 WoS30 Europe PMC16
    2019 Fuchs, C. J., Kouw, I. W. K., Churchward-Venne, T. A., Smeets, J. S. J., Senden, J. M., Lichtenbelt, W. D. V. M., . . . van Loon, L. J. C. (2019). Post-exercise Cooling Impairs Muscle Protein Synthesis Rates In Healthy Young Males. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 51(6), 543.
    DOI
    2018 Trommelen, J., Kouw, I., Holwerda, A., Snijders, T., Halson, S., Rollo, I., . . . van Loon, L. (2018). Presleep dietary protein-derived amino acids are incorporated in myofibrillar protein during postexercise overnight recovery. American journal of physiology. Endocrinology and metabolism, 314(5), E457-E467.
    DOI Scopus48 WoS44 Europe PMC27
    2017 Nyakayiru, J., Kouw, I. W., Cermak, N. M., Senden, J. M., van Loon, L. J., & Verdijk, L. B. (2017). Erratum: Sodium nitrate ingestion increases skeletal muscle nitrate content in humans. J Appl Physiol 123: 637– 644, 2017. First published June 29, 2017; doi:10.1152/japplphysiol.01036.2016. Journal of Applied Physiology, 123(6), 1738.
    DOI
    2017 Gorissen, S., Horstman, A., Franssen, R., Kouw, I., Wall, B., Burd, N., . . . Van Loon, L. (2017). Habituation to low or high protein intake does not modulate basal or postprandial muscle protein synthesis rates: A randomized trial. American Journal of Clinical Nutrition, 105(2), 332-342.
    DOI Scopus34 WoS35 Europe PMC21
    2017 Kramer, I., Verdijk, L., Hamer, H., Verlaan, S., Luiking, Y., Kouw, I., . . . van Loon, L. (2017). Both basal and post-prandial muscle protein synthesis rates, following the ingestion of a leucine-enriched whey protein supplement, are not impaired in sarcopenic older males. Clinical Nutrition, 36(5), 1440-1449.
    DOI Scopus27 WoS24 Europe PMC15
    2017 Nyakayiru, J., Kouw, I., Cermak, N., Senden, J., Van Loon, L., & Verdijk, L. (2017). Sodium nitrate ingestion increases skeletal muscle nitrate content in humans. Journal of Applied Physiology, 123(3), 637-644.
    DOI Scopus30 WoS31 Europe PMC16
    2017 Kouw, I., Holwerda, A., Trommelen, J., Kramer, I., Bastiaanse, J., Halson, S., . . . van Loon, L. (2017). Protein ingestion before sleep increases overnight muscle protein synthesis rates in healthy older men: A randomized controlled trial. Journal of Nutrition, 147(12), 2252-2261.
    DOI Scopus61 WoS58 Europe PMC36
    2016 Klinkenberg, L., Wildi, K., Van Der Linden, N., Kouw, I., Niens, M., Twerenbold, R., . . . Meex, S. (2016). Diurnal rhythm of cardiac troponin: Consequences for the diagnosis of acute myocardial infarction. Clinical Chemistry, 62(12), 1602-1611.
    DOI Scopus57 WoS57 Europe PMC21
    2016 Trommelen, J., Holwerda, A., Kouw, I., Langer, H., Halson, S., Rollo, I., . . . Van Loon, L. (2016). Resistance Exercise Augments Postprandial Overnight Muscle Protein Synthesis Rates. Medicine and Science in Sports and Exercise, 48(12), 2517-2525.
    DOI Scopus43 WoS42 Europe PMC28
    2016 Kouw, I., Cermak, N., Burd, N., Churchward-Venne, T., Senden, J., Gijsen, A., & van Loon, L. (2016). Sodium nitrate co-ingestion with protein does not augment postprandial muscle protein synthesis rates in older, type 2 diabetes patients. American Journal of Physiology - Endocrinology and Metabolism, 311(2), E325-E334.
    DOI Scopus7 WoS6 Europe PMC6
    2016 Holwerda, A., Kouw, I., Trommelen, J., Halson, S., Wodzig, W., Verdijk, L., & van Loon, L. (2016). Physical activity performed in the evening increases the overnight muscle protein synthetic response to presleep protein ingestion in older men. Journal of Nutrition, 146(7), 1307-1314.
    DOI Scopus43 WoS42 Europe PMC25
    2016 Trommelen, J., Holwerda, A. M., Kouw, I. W. K., Halson, S. L., Verdijk, L. B., & van Loon, L. J. C. (2016). Protein Ingestion Before Sleep Provides Precursors For Post-exercise Overnight De Novo Muscle Protein Synthesis. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 48(5), 4.
    DOI
    2016 Holwerda, A. M., Kouw, I. W. K., Trommelen, J., Halson, S. L., Wodzig, W. K. W. H., Verdijk, L. B., & van Loon, L. J. C. (2016). Exercise Enhances The Overnight Muscle Protein Synthetic Response To Pre-sleep Protein Feeding In Older Males. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 48(5), 3.
    DOI
    2015 Kramer, I. F., Verdijk, L. B., Hamer, H. M., Verlaan, S., Luiking, Y., Kouw, I. W. K., . . . Van Loon, L. J. C. (2015). Impact of the macronutrient composition of a nutritional supplement on muscle protein synthesis rates in older men: A randomized, double blind, controlled trial. Journal of Clinical Endocrinology and Metabolism, 100(11), 4124-4132.
    DOI Scopus25 WoS22 Europe PMC13
    2015 Kouw, I. W. K., Gorissen, S. H. M., Burd, N. A., Cermak, N. M., Gijsen, A. P., Van Kranenburg, J., & Van Loon, L. J. C. (2015). Postprandial protein handling is not impaired in type 2 diabetes patients when compared with normoglycemic controls. Journal of Clinical Endocrinology and Metabolism, 100(8), 3103-3111.
    DOI Scopus16 WoS15 Europe PMC14
    2015 Cermak, N. M., Hansen, D., Kouw, I. W. K., van Dijk, J. W., Blackwell, J. R., Jones, A. M., . . . van Loon, L. J. C. (2015). A single dose of sodium nitrate does not improve oral glucose tolerance in patients with type 2 diabetes mellitus. Nutrition Research, 35(8), 674-680.
    DOI Scopus19 WoS19 Europe PMC13
    2014 Burd, N. A., Cermak, N. M., Kouw, I. W. K., Gorissen, S. H., Gijsen, A. P., & Van Loon, L. J. C. (2014). The use of doubly labeled milk protein to measure postprandial muscle protein synthesis rates in vivo in humans. Journal of Applied Physiology, 117(11), 1363-1370.
    DOI Scopus32 WoS33 Europe PMC22
    2011 Kouw, I. W., Tieland, M., & Gorissen, S. H. (2011). A step towards underpinning the molecular signalling events regulating muscle protein loss in critically ill patients. Journal of Physiology, 589(24), 5925-5926.
    DOI
  • Position: Ext-Funded Research Fellow (B)
  • Phone: 70741757
  • Email: imre.kouw@adelaide.edu.au
  • Campus: North Terrace
  • Building: 30, floor 4/G
  • Org Unit: Medical Specialties

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