Dr Hui Li

Grant-Funded Researcher (A)

School of Biomedicine

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Dr. Li is a postdoctoral researcher in the Adelaide Medical School, University of Adelaide, and located in the Centre for Nutrition and Gastrointestinal Diseases at the South Australian Health and Medical Research Institute.

My Research
Career
Publications
Teaching
Supervision
Professional Activities
Contact

Dr. Li has a research interest in gastric vagal afferent signalling in health and diseases. By using multiple complex techniques, including electrophysiology and laser capture microdissection, she has significantly advanced understanding on the interaction between gastric appetite regulatory hormones and gastric vagal afferents, and has found this system is dynamic changing with nutritional states (e.g. food restriction and obesity). These findings have improved understandings of the role vagal afferents play in appetite regulation and obesity. She is also interested in understanding the physiological and molecular basis of functional dyspepsia, particularly its mechanisms via gastric vagal afferents. These studies will led to new understanding of diseases associated with vagal afferents and provide potential treatment regime or pharmacotherapies for treatment of these diseases.

Appointments

Date	Position	Institution name
2017 - ongoing	Research Fellow	South Australian Health and Medical Research Institute
2014 - ongoing	Postdoctoral Research Fellow	University of Adelaide, Adelaide
2013 - 2014	Research assistant	University of Adelaide, Adelaide

Awards and Achievements

Date	Type	Title	Institution Name	Country
2019	Award	2019 Bliss* Adelaide Best Poster Presentation First Place	Bliss* Adelaide EMCR Symposium	Australia
2016	Award	2016 SAHMRI Research Showcase Poster Session Early Career Researcher Prize	South Australian Health And Medical Research Institute	Australia
2015	Award	2015 ANGMA Young Investigator Award	Australasian NeuroGastroenterology & Motility Association	Australia

Language Competencies

Language Competency

Chinese (Mandarin) Can read, write, speak, understand spoken and peer review

English Can read, write, speak, understand spoken and peer review

Language	Competency
Chinese (Mandarin)	Can read, write, speak, understand spoken and peer review
English	Can read, write, speak, understand spoken and peer review

Education

Date	Institution name	Country	Title
2009 - 2014	University of Adelaide, Adelaide	Australia	Doctor of Philosophy (PhD)
2004 - 2008	Shandong University, Jinan	China	Master in Nutrition and Food Hygiene
1999 - 2004	Shanxi Medical University, Taiyuan	China	Bachelor in Preventive Medicine

Research Interests

Gastroenterology and Hepatology Nutritional Physiology

Journals

Year	Citation
2022	Li, H., & Page, A. J. (2022). Altered Vagal Signaling and Its Pathophysiological Roles in Functional Dyspepsia. Frontiers in Neuroscience, 16, 858612. DOI
2021	Lim, S. M., Choo, J. M., Li, H., O'Rielly, R., Carragher, J., Rogers, G. B., . . . Muhlhausler, B. (2021). A high amylose wheat diet improves gastrointestinal health parameters and gut microbiota in male and female mice. Foods, 10(2), 1-18. DOI Scopus1 WoS1 Europe PMC1
2021	Nunez Salces, M., Li, H., Young, R. L., & Page, A. J. (2021). The secretion of total and acyl ghrelin from the mouse gastric mucosa: Role of nutrients and the lipid chemosensors FFAR4 and CD36. Peptides, 146, 170673-1-170673-9. DOI
2021	Huang, K. P., Goodson, M. L., Vang, W., Li, H., Page, A. J., & Raybould, H. E. (2021). Leptin signaling in vagal afferent neurons supports the absorption and storage of nutrients from high-fat diet. International Journal of Obesity, 45(2), 348-357. DOI Scopus7 WoS6 Europe PMC5
2020	Christie, S., O'Reilly, R., Li, H., Wittert, G. A., & Page, A. J. (2020). Biphasic effects of methanandamide on murine gastric vagal afferent mechanosensitivity. The Journal of Physiology, 598(1), 139-150. DOI Scopus8 WoS10 Europe PMC6
2020	Page, A., Christie, S., Symonds, E., & Li, H. (2020). Circadian regulation of appetite and time restricted feeding. Physiology and Behavior, 220, 10 pages. DOI Scopus9 WoS9 Europe PMC3
2020	Kaur, H., Muhlhausler, B. S., Sim, P. S. -L., Page, A., Li, H., Nunez Salces, M., . . . Gatford, K. L. (2020). Pregnancy, but not dietary octanoic acid supplementation, stimulates the ghrelin-pituitary growth. J Endocrinol, 245(2), 327-342. DOI Scopus8 WoS8 Europe PMC3
2020	Christie, S., O'Rielly, R., Li, H., Nunez-Salces, M., Wittert, G. A., & Page, A. J. (2020). Modulatory effect of methanandamide on gastric vagal afferent satiety signals depends on nutritional status. The Journal of Physiology, 598(11), 2169-2182. DOI Scopus7 WoS6 Europe PMC4
2020	Nunez-Salces, M., Li, H., Feinle-Bisset, C., Young, R. L., & Page, A. J. (2020). Nutrient-sensing components of the mouse stomach and the gastric ghrelin cell. Neurogastroenterology & Motility, 32(12), 1-13. DOI Scopus7 WoS7 Europe PMC3
2020	Christie, S., O'Rielly, R., Li, H., Wittert, G., & Page, A. (2020). High fat diet induced obesity alters endocannabinoid and ghrelin mediated regulation of components of the endocannabinoid system in nodose ganglia. Peptides, 131, 170371-1-170371-7. DOI Scopus2 WoS2 Europe PMC1
2020	O'Rielly, R., Li, H., Lim, S. M., Yazbeck, R., Kritas, S., Ullrich, S. S., . . . Page, A. J. (2020). The effect of isoleucine supplementation on body weight gain and blood glucose response in lean and obese mice. Nutrients, 12(8), 1-12. DOI Scopus7 WoS7 Europe PMC2
2020	Nunez-Salces, M., Li, H., Christie, S., & Page, A. J. (2020). The effect of high-fat diet-induced obesity on the expression of nutrient chemosensors in the mouse stomach and the gastric ghrelin cell. Nutrients, 12(9), 1-14. DOI Scopus4 WoS4 Europe PMC1
2020	Li, H., Clarke, G. S., Christie, S., Ladyman, S. R., Kentish, S. J., Young, R. L., . . . Page, A. J. (2020). Pregnancy-related plasticity of gastric vagal afferent signals in mice.. American journal of physiology. Gastrointestinal and liver physiology, 320(2), 10 pages. DOI Scopus4 WoS4 Europe PMC2
2020	Nunez Salces, M., Li, H., Feinle-Bisset, C., Young, R. L., & Page, A. J. (2020). The regulation of gastric ghrelin secretion.. Acta Physiol (Oxf), 231(3), e13588. DOI Scopus8 WoS8 Europe PMC2
2019	Li, H., & Page, A. J. (2019). Activation of CRF2 receptor increases gastric vagal afferent mechanosensitivity.. Journal of neurophysiology, 122(6), 2636-2642. DOI WoS1
2019	Lim, S. M., Page, A. J., Li, H., Carragher, J., Searle, I., Robertson, S., & Muhlhausler, B. (2019). Sexually Dimorphic Response of Increasing Dietary Intake of High Amylose Wheat on Metabolic and Reproductive Outcomes in Male and Female Mice.. Nutrients, 12(1), 14 pages. DOI Scopus1 WoS1 Europe PMC1
2019	Kentish, S. J., Christie, S., Vincent, A., Li, H., Wittert, G. A., & Page, A. J. (2019). Cover Image. Neurogastroenterology & Motility, 31(12). DOI
2019	Li, H., Buisman-Pijlman, F. T. A., Nunez-Salces, M., Christie, S., Frisby, C. L., Inserra, A., . . . Page, A. J. (2019). Chronic stress induces hypersensitivity of murine gastric vagal afferents.. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 31(12), e13669. DOI Scopus12 WoS9 Europe PMC4
2019	Kentish, S. J., Christie, S., Vincent, A., Li, H., Wittert, G. A., & Page, A. J. (2019). Disruption of the light cycle ablates diurnal rhythms in gastric vagal afferent mechanosensitivity. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 31(12), e13711. DOI Scopus5 WoS5 Europe PMC1
2018	Page, A., & Li, H. (2018). Meal-sensing signaling pathways in functional dyspepsia. Frontiers in Systems Neuroscience, 12, 9 pages. DOI Scopus7 WoS8 Europe PMC3
2018	Kentish, S. J., Hatzinikolas, G., Li, H., Frisby, C. A., Wittert, G. A., & Page, A. J. (2018). Time-restricted feeding prevents ablation of diurnal rhythms in gastric vagal afferent mechanosensitivity observed in high-fat diet-induced obese mice. The Journal of Neuroscience, 38(22), 5088-5095. DOI Scopus19 WoS18 Europe PMC9
2018	Li, H., Kentish, S., Wittert, G., & Page, A. (2018). Apelin modulates murine gastric vagal afferent mechanosensitivity. Physiology and Behavior, 194, 466-473. DOI Scopus7 WoS8 Europe PMC1
2018	Christie, S., Wittert, G. A., Li, H., & Page, A. J. (2018). Involvement of TRPV1 Channels in Energy Homeostasis. Frontiers in Endocrinology, 9, 14 pages. DOI Scopus50 WoS52 Europe PMC28
2018	Christie, S., Vincent, A., Li, H., Frisby, C., Kentish, S., O'Rielly, R., . . . Page, A. (2018). A rotating light cycle promotes weight gain and hepatic lipid storage in mice. American Journal of Physiology - Gastrointestinal and Liver Physiology, 315(6), 932-941. DOI Scopus16 WoS18 Europe PMC10
2018	Li, H., Kentish, S., Wittert, G., & Page, A. (2018). The role of neuropeptide W in energy homeostasis. Acta Physiologica, 222(1), e12884-1-e12884-12. DOI Scopus4 WoS2 Europe PMC2
2017	Kentish, S., Li, H., Frisby, C., & Page, A. (2017). Nesfatin-1 modulates murine gastric vagal afferent mechanosensitivity in a nutritional state dependent manner. Peptides, 89, 35-41. DOI Scopus15 WoS14 Europe PMC7
2015	Kentish, S., Ratcliff, K., Li, H., Wittert, G., & Page, A. (2015). High fat diet induced changes in gastric vagal afferent response to adiponectin. Physiology & Behavior, 152(Part B), 354-362. DOI Scopus15 WoS16 Europe PMC12
2015	Kentish, S., Frisby, C., Kritas, S., Li, H., Hatzinikolas, G., O'Donnell, T., . . . Page, A. (2015). TRPV1 channels and gastric vagal afferent signalling in lean and high fat diet induced obese mice. PLoS One, 10(8), e0135892-1-e0135892-15. DOI Scopus31 WoS30 Europe PMC22
2015	Li, H., Frisby, C., O'Donnell, T., Kentish, S., Wittert, G., & Page, A. (2015). Neuropeptide W modulation of gastric vagal afferent mechanosensitivity: impact of age and sex. Peptides, 71, 141-148. DOI Scopus4 WoS4 Europe PMC5
2014	Kentish, S., O'Donnell, T., Frisby, C., Li, H., Wittert, G., & Page, A. (2014). Altered gastric vagal mechanosensitivity in diet-induced obesity persists on return to normal chow and is accompanied by increased food intake. International Journal of Obesity, 38(5), 636-642. DOI Scopus36 WoS27 Europe PMC24
2014	Li, H., Feinle-Bisset, C., Frisby, C., Kentish, S., Wittert, G., & Page, A. (2014). Gastric neuropeptide W is regulated by meal-related nutrients. Peptides, 62, 6-14. DOI Scopus10 WoS9 Europe PMC5
2013	Li, H., Kentish, S., Kritas, S., Young, R., Isaacs, N., O'Donnell, T., . . . Page, A. (2013). Modulation of murine gastric vagal afferent mechanosensitivity by neuropeptide W. Acta Physiologica (Print Edition), 209(2), 179-191. DOI Scopus16 WoS17 Europe PMC8
2013	Kentish, S., O'Donnell, T., Isaacs, N., Young, R., Li, H., Harrington, A., . . . Page, A. (2013). Gastric vagal afferent modulation by leptin is influenced by food intake status. Journal of Physiology-London, 591(7), 1921-1934. DOI Scopus64 WoS64 Europe PMC45
2012	Kentish, S., Li, H., Philp, L., O'Donnell, T., Isaacs, N., Young, R., . . . Page, A. (2012). Diet-induced adaptation of vagal afferent function. Journal of Physiology-London, 590(1), 209-221. DOI Scopus96 WoS95 Europe PMC63

Book Chapters

Year	Citation
2021	Page, A., & Li, H. (2021). Molecular Signaling in the Gut–Brain Axis in Stress. In G. Fink (Ed.), Stress: Genetics, Epigenetics and Genomics (Vol. 4, pp. 135-143). London, United Kingdom: Academic Press. DOI
2018	Page, A., & Li, H. (2018). Gastrointestinal mechanosensory function in health and disease. In S. Verbruggen (Ed.), Mechanobiology in Health and Disease (pp. 377-414). United Kingdom: Academic Press. DOI Scopus2

Conference Items

Year	Citation
2020	Li, H., & Page, A. J. (2020). Activation of CRF2 receptor increases gastric vagal afferent mechanosensitivity. Poster session presented at the meeting of NEUROGASTROENTEROLOGY AND MOTILITY. WILEY.
2016	Li, H., Frisby, C., Wittert, G., & Page, A. (2016). NADPH oxidase modulates leptin effects on gastric vagal afferent mechanosensitivity.. Poster session presented at the meeting of Society for the Study of Ingestive Behavior. Porto, Portugal..
2015	Li, H., kentish, S., frisby, C., wittert, G., & page, A. (2015). Modulatory effect of apelin on gastric vagal afferents mechanosensitivity in different feeding status. Poster session presented at the meeting of Australasian Neurogastroenterology & metabolity association annual conference. Adelaide, Australia.
2014	Li, H., Frisby, C. L., O'Donnell, T. A., Kentish, S. J., Wittert, G. A., & Page, A. J. (2014). Neuropeptide W modulation of gastric vagal afferent mechanosensitivity: impact of age and gender. Poster session presented at the meeting of Abstracts of the 1st Federation Neurogastroenterology and Motility Scientific Meeting, as published in Neurogastroenterology and Motility. Guangzhou, China: Wiley.
2012	Li, H., kentish, S., O'Donnell, T., Wittert, G., Blackshaw, A., & PAGE, A. (2012). The role of gastric neuropeptide W is regulated by food intake. Poster session presented at the meeting of Australian and New Zealand Obesity Society.
2011	Li, H., KENTISH, S., O'Donnell, T., wittert, G., Blackshaw, A., & PAGE, A. (2011). The effect of NPW on the mechanosensitivity of gastro-oesophageal vagal afferents. Poster session presented at the meeting of Digestive Disease Week 2011. Chicago, United States of America.

Dr. Li has acted as a tutor for the undergraduate Food, Nutrition & Health classes at the University of Adelaide in 2012.

Current Higher Degree by Research Supervision (University of Adelaide)

Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
2021	Co-Supervisor	The Role of NOX-Dependent ROS in Leptin Modulation of Gastric Vagal Afferent Satiety Signals	Doctor of Philosophy	Doctorate	Full Time	Miss Elaheh Heshmati

Past Higher Degree by Research Supervision (University of Adelaide)

Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
2017 - 2020	Co-Supervisor	Endocannabinoid regulation of gastric vagal afferent signalling	Doctor of Philosophy	Doctorate	Full Time	Dr Stewart Ramsay
2017 - 2021	Co-Supervisor	Dietary, Lifestyle and Pharmaceutical Interventions for the Treatment of Metabolic Diseases	Doctor of Philosophy	Doctorate	Full Time	Miss Rebecca Jane O'Rielly
2016 - 2020	Co-Supervisor	The nutrient-sensing mechanisms of the mouse stomach and the ghrelin cell in health and obesity	Doctor of Philosophy	Doctorate	Full Time	Miss Maria Nunez

Committee Memberships

Date	Role	Committee	Institution	Country
2018 - ongoing	Board Member	Reconciliation Action Plan committee	SAHMRI	Australia
2018 - ongoing	Board Member	Faculty Seminar Series Organising Committee	University of Adelaide	Australia

Memberships

Date	Role	Membership	Country
2019 - ongoing	Board Member	Australian Society for Medical Research	Australia
2016 - ongoing	Member	Australian and New Zealand Obesity Society
2015 - 2016	Member	The Australian Society For Medical Research

Position: Grant-Funded Researcher (A)
Phone: 81284856
Email: hui.li01@adelaide.edu.au
Campus: North Terrace
Building: SAHMRI, floor 7
Org Unit: Medical Sciences