
Professor Harshita Pant
Professor
School of Biomedicine
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Professor Harshita Pant is a rhinologist and skull base surgeon, and research leader at the Adelaide Centre of Epigenetics (ACE), at the University of Adelaide. She heads the Adelaide University’s Otolaryngology, Head & Neck Surgery Clinical Epigenetics Research and has a private clinical practice at Calvariam ENT.
Prof Pant is clinical lead of the Allergy and Cancer Immunology Laboratory at the Centre for Cancer Biology ((CCB) an alliance between SA Pathology and University of South Australia) and works closely with laboratory head, Dr Damon Tumes. Allergy and Cancer Immunology Laboratory - Centre for Cancer Biology
Her group’s cutting-edge academic program focuses on uncovering epigenetic mechanisms in chronic airway inflammation (allergies, chronic rhinosinusitis (CRS), nasal polyps and asthma) and head and neck cancer. Her goal is to develop precision diagnostics and novel treatments for these patients, including epigenetic reprogramming, using innovative multi-omic technology and AI.
Prof Pant’s research in CRS airway inflammation has resulted in significant industry collaborations, improved access to monoclonal antibody treatments in Australia for patients with severe nasal polyposis, and patents for novel steroid-sparing topical therapy for CRS patients undergoing endoscopic sinus surgery. Her current work has led to multidisciplinary, trait-based care-models for CRS and is leading the first multi-disciplinary precision medicine clinical trial aimed at reducing oral steroid and antibiotic use in CRS/asthma patients. Healthy investment in better patient outcomes | Newsroom | University of Adelaide
Her group’s recent discoveries in cancer research highlight the role of the tumour microenvironment, in particular, cancer-associated fibroblasts in biologically aggressive disease and have identified eosinophils as new contributors to immune dysfunction in head and cancer. Overcoming immune exhaustion in recurrent head and neck cancer - Passe & Williams Foundation
Her research group is driven by curiosity, creativity, compassion, and collaboration. With a strong focus on translating discoveries into real-world impact, we offer exciting research opportunities incorporating hands-on lab work with clinical trials where students can work with renowned scientists and clinicians at the Centre for Cancer Biology (Bradley Building), the Royal Adelaide Hospital, and the University of Adelaide (ACE, Level 6, AHMS). More information about current projects can be found here Pant Research Group: Otolaryngology, Head & Neck Surgery Clinical Epigenetics | Adelaide Centre for Epigenetics (ACE) | University of Adelaide
Our projects are ideal for both undergraduate and postgraduate students from clinical and science backgrounds. We welcome highly motivated individuals who are passionate about research, embracing diverse perspectives and varying levels of experience—including those new to the field. With a proven track record in HDR supervision, we are committed to fostering a dynamic, nurturing, and inspiring environment where students can learn, explore, and excel.
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Appointments
Date Position Institution name 2023 - ongoing Academic Professor University of Adelaide 2016 - ongoing Clinical Associate Professor University of Adelaide -
Education
Date Institution name Country Title The Flinders University of South Australia Australia BMBS The University of Adelaide Australia PhD -
Postgraduate Training
Date Title Institution Country FRACS Royal Australasian College of Surgeons Australia Clinical Instructor The University of Pittsburgh Medical Centre United States -
Research Interests
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Journals
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Book Chapters
Year Citation 2024 Pant, H., Morrow, R., Tumes, D., & Seethala, R. (2024). Pathology of Nasal Polyps. In Nasal Polyposis and its Management Pathogenesis, Medical and Surgical Treatment Second Edition (pp. 23-34). Springer International Publishing.
DOI2024 Pant, H. (2024). Categorization of Nasal Polyps. In Nasal Polyposis and its Management Pathogenesis, Medical and Surgical Treatment Second Edition (pp. 135-142). Springer International Publishing.
DOI2018 Snyderman, C., Gardner, P., & Pant, H. (2018). Juvenile Angiofibroma. In E. Myers, & C. Snyderman (Eds.), Operative Otolaryngology: Head and Neck Surgery (3 ed.). Elsevier Health Sciences. 2014 Pant, H., Snyderman, C., Tyler-Kabara, E., Pinheiro-Neto, C., Koutourousiou, M., Fernandez-Miranda, J., . . . Gardner, P. (2014). Pediatric Skull Base Surgery. In C. Bluestone, & J. Simons (Eds.), Bluestone and Stool's Pediatric Otolaryngology (pp. 1919-1942). PMPH-USA. 2012 Snyderman, C. H., Pant, H., Kassam, A. B., Carrau, R. L., Prevedello, D. M., & Gardner, P. A. (2012). The learning curve for endonasal surgery of the cranial base: a systematic approach to training. In A. B. Kassam, & P. A. Gardner (Eds.), Endoscopic approaches to the skull base (Vol. 26, pp. 222-231). Karger.
DOI Scopus42012 Snyderman, C. H., Pant, H., Gardner, P. A., Carrau, R. L., Prevedello, D. M., & Kassam, A. B. (2012). Management of complications of endonasal cranial base surgery. In A. B. Kassam, & P. A. Gardner (Eds.), Endoscopic Approaches to the Skull Base (Vol. 26, pp. 182-190). Karger.
DOI Scopus22010 Seethala, R. R., & Pant, H. (2010). Pathology of nasal polyps. In Nasal Polyposis: Pathogenesis, Medical and Surgical Treatment (pp. 17-26). Springer Berlin Heidelberg.
DOI Scopus52010 Seethala, R. R., & Pant, H. (2010). Pathology of nasal polyps. In Nasal Polyposis: Pathogenesis, Medical and Surgical Treatment (pp. 17-26). Springer Berlin Heidelberg.
DOI Scopus52010 Ferguson, B. J., Rizk, H., Ramakrishnan, J., & Pant, H. (2010). Categorization of nasal polyps. In T. M. Önerci, & B. J. Ferguson (Eds.), Nasal polyposis: pathogenesis, medical and surgical treatment (pp. 103-110). Springer-Verlag.
DOI Scopus32010 Weitzel, E. K., Pant, H., Thwin, M., & Wormald, P. J. (2010). Nasal polyposis: aggressive sinus marsupialization including the endoscopic modified lothrop procedure. In T. M. Önerci, & B. J. Ferguson (Eds.), Nasal polyposis: pathogenesis, medical and surgical treatment (pp. 289-296). Springer Berlin Heidelberg.
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Conference Papers
Year Citation 2018 Wilson, N. J., Yip, K., Woodman, N., Ng, M., Alhamdoosh, M., Pant, H., . . . Owczarek, C. M. (2018). Novel therapeutic anti-beta common monoclonal antibody, csl311, affects gene transcriptional pathways contributing to the pathogenesis of chronic rhinosinusitis with nasal polyps. In ALLERGY Vol. 73 (pp. 31). Munich, GERMANY: WILEY. -
Conference Items
Year Citation 2017 Owczarek, C. M., Yip, K. -H., Pant, H., Vairo, G., Lopez, A., Nash, A. D., . . . Grimbaldeston, M. A. (2017). Novel Therapeutic Mab Csl311 For Treatment Of Chronic RhINOSinusitis With Nasal Polyps. Poster session presented at the meeting of AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. Washington, DC: AMER THORACIC SOC. 2016 Owczarek, C. M., Grimbaldeston, M., Dhagat, U., Panousis, C., Gauvreau, G. M., Sehmi, R., . . . Wilson, N. (2016). Novel Anti-βc Receptor Antibody Targets Multiple Effector Cell Populations In Human Nasal Polyps Transplanted Into Immunodeficient Transgenic Human Interleukin-3 (il-3)/granulocyte-Macrophage Colony Stimulating Factor (gm-Csf) Knock-In Mice. Poster session presented at the meeting of AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. San Francisco, CA: AMER THORACIC SOC.
- MRFF Preventive and Public Health Research Initiative Chronic Respiratory Conditions Grant Proposal (2024-2028).
CIA. Reducing Steroid and Antibiotic Use in Rhinosinusitis and Asthma with Precision Medicine. Value = $1,811,683 AUD. - Neurosurgical Research Foundation (2024) AI $AUD 50, 000
- NHMRC Ideas Grant (2021-2024) CI with Prof Angel Lopez; Dr Damon Tumes; Dr Luciano Martelotto; Dr Nicholas Wilson Resolving eosinophil and inflammatory heterogeneity in chronic allergic airway disease for safer, effective and lasting precision therapies. Value: $AUD 1,166165.00
- Channel 7 Children's Research Foundation (2022-2024) CI with Dr Damon Tumes; Anita Kral. Does airway epithelial progenitor cell reprogramming by viral and bacterial infections cause childhood asthma? Value: $99,188.00
- Garnett Passe and Rodney Williams Memorial Foundation Junior Fellowship (2022) Dr Carly Whyte. Defining the therapeutic potential of eosinophils in head and neck cancer.
- NHMRC Project Grant (2017-2019) with Prof. Angel Lopez; A/Prof. Michele Grimbaldeston. Novel approaches to control mast cell function in allergic inflammation. Value: $AUD 723,447.00
Years 4 and 5
- Year 5 School of Medicine Teaching Series (2012 to current): ENT teaching
- Year 4 Surgical home unit (2012 to current) ENT teaching
- Year 4/5 Coordinator (2018)
- School of Medicine Teaching Series Coordinator (2012-2018)
Adelaide University Surgical Society
- Beneath the Scrubs event mentor: Professionalism, respect, inclusivity and diversity in medicine/surgery. Health care for professionals.
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2023 Principal Supervisor Immunological determinants of head and neck cancer progression and metastasis, in particular the role of cancer associated fibroblasts Master of Philosophy (Surgery) Master Full Time Miss Laura Kenyon -
Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2010 - 2012 Co-Supervisor The Environment and the Host in Chronis Rhinosinusitis Doctor of Philosophy Doctorate Full Time Dr Samuel Joseph Boase -
Other Supervision Activities
Date Role Research Topic Location Program Supervision Type Student Load Student Name 2021 - ongoing Co-Supervisor Therapeutic potential of eosinophils in head and neck cancer The University of South Australia - Postdoctorate - Dr Carly Whyte 2020 - ongoing Co-Supervisor Deciphering how airway epithelial programming and inflammation cause chronic allergic airways disease The University of South Australia PhD Doctorate Part Time Anita Kral 2018 - 2018 Principal Supervisor Single cell transcriptional analysis of nasal polyps: a novel approach to the molecular basis of disease The University of Adelaide MBBS Honours Full Time Angus Sarah
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