| 2025 |
Skarne, N., D'Souza, R. C. J., Palethorpe, H. M., Bradbrook, K. A., Gomez, G. A., & Day, B. W. (2025). Personalising glioblastoma medicine: explant organoid applications, challenges and future perspectives. Acta Neuropathologica Communications, 13(1, article no. 6), 14 pages. DOI Scopus5 WoS4 Europe PMC2 |
| 2024 |
Zadeh Shirazi, A., Tofighi, M., Gharavi, A., & Gomez, G. A. (2024). The application of artificial intelligence to cancer research: a comprehensive guide. Technology in Cancer Research and Treatment, 23, 1-20. DOI |
| 2024 |
Gomez, G. A. (2024). Cells play tug-of-war to start moving collectively. Nature Physics, 20(2), 189-190. DOI |
| 2023 |
Han, P., Guo, T., Jayasree, A., Gomez, G. A., Gulati, K., & Ivanovski, S. (2023). Tunable nano-engineered anisotropic surface for enhanced mechanotransduction and soft-tissue integration. Nano Research, 16(5), 7293-7303. DOI |
| 2023 |
Mahdi Esferizi, R., Haji Molla Hoseyni, B., Mehrpanah, A., Golzade, Y., Najafi, A., Elahian, F., . . . Tahmasebian, S. (2023). DeeP4med: deep learning for P4 medicine to predict normal and cancer transcriptome in multiple human tissues. Bmc Bioinformatics, 24(1, article no. 275), 1-22. DOI |
| 2023 |
Han, P., Gomez, G. A., Duda, G. N., Ivanovski, S., & Poh, P. S. P. (2023). Scaffold geometry modulation of mechanotransduction and its influence on epigenetics. Acta Biomaterialia, 163, 259-274. DOI |
| 2023 |
Kan, W. L., Dhagat, U., Hercus, T. R., Kaufmann, K. B., Nero, T. L., Zeng, A. G. X., . . . Lopez, A. (2023). Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia. Cancer Discovery, 13(8), 1922-1947. DOI Scopus9 WoS8 Europe PMC9 |
| 2023 |
Scheer, K. G., Ebert, L. M., Samuel, M. S., Bonder, C. S., & Gomez, G. A. (2023). Bevacizumab-Induced Hypertension in Glioblastoma Patients and Its Potential as a Modulator of Treatment Response. Hypertension, 80(8), 1590-1597. DOI Scopus10 WoS9 Europe PMC9 |
| 2022 |
Kollis, P. M., Ebert, L. M., Toubia, J., Bastow, C. R., Ormsby, R. J., Poonnoose, S. I., . . . Gargett, T. (2022). Characterising Distinct Migratory Profiles of Infiltrating T-Cell Subsets in Human Glioblastoma. Frontiers in immunology, 13, 850226-1-850226-19. DOI Scopus23 WoS21 Europe PMC18 |
| 2022 |
Farahani, M., Carthew, J., Bhowmik, S., Shard, C., Nunez Nescolarde, A., Gomez, G. A., . . . Frith, J. E. (2022). Emerging biomaterials and technologies to control stem cell fate and patterning in engineered 3D tissues and organoids. Biointerphases, 17(6), 1-26. DOI |
| 2022 |
Wu, S. K., Gomez, G. A., Stehbens, S., Acharya, B. R., Ratheesh, A., Priya, R., . . . Bershadsky, A. (2022). Editorial: Forces in biology - Cell and developmental mechanobiology and its implications in disease - Volume II. Frontiers in Cell and Developmental Biology, 10(1082857.), 1-3. DOI |
| 2022 |
Bonfim Melo, A., Duszyc, K., Gomez, G. A., & Yap, A. S. (2022). Regulating life after death: how mechanical communication mediates the epithelial response to apoptosis. European Physical Journal E, 45(1, article no. 9), 1-8. DOI |
| 2021 |
Duszyc, K., Gomez, G. A., Lagendijk, A. K., Yau, M. K., Nanavati, B. N., Gliddon, B. L., . . . Yap, A. S. (2021). Mechanotransduction activates RhoA in the neighbors of apoptotic epithelial cells to engage apical extrusion. Current Biology, 31(6), 1326-1336. DOI Scopus47 WoS46 Europe PMC47 |
| 2021 |
Lenin, S., Ponthier, E., Scheer, K. G., Yeo, E. C. F., Tea, M. N., Ebert, L. M., . . . Gomez, G. A. (2021). A drug screening pipeline using 2D and 3D patient-derived in vitro models for pre-clinical analysis of therapy response in glioblastoma. International Journal of Molecular Sciences, 22(9), 4322-1-4322-27. DOI Scopus38 WoS37 Europe PMC35 |
| 2021 |
Zadeh Shirazi, A., McDonnell, M. D., Fornaciari, E., Bagherian, N. S., Scheer, K. G., Samuel, M. S., . . . Gomez, G. A. (2021). A deep convolutional neural network for segmentation of whole-slide pathology images identifies novel tumour cell-perivascular niche interactions that are associated with poor survival in glioblastoma. British Journal of Cancer, 125(3), 337-350. DOI Scopus32 WoS24 Europe PMC29 |
| 2020 |
Zadeh Shirazi, A., Fornaciari, E., Bagherian, N. S., Ebert, L. M., Koszyca, B., & Gomez, G. A. (2020). DeepSurvNet: deep survival convolutional network for brain cancer survival rate classification based on histopathological images. Medical and Biological Engineering and Computing, 58(5), 1031-1045. DOI Scopus52 WoS42 Europe PMC35 |
| 2020 |
Ebert, L. M., Yu, W., Gargett, T., Toubia, J., Kollis, P. M., Tea, M. N., . . . Brown, M. P. (2020). Endothelial, pericyte and tumor cell expression in glioblastoma identifies fibroblast activation protein (FAP) as an excellent target for immunotherapy. Clinical and Translational Immunology, 9(10), 1-24. DOI Scopus51 WoS48 Europe PMC47 |
| 2020 |
Shirazi, A. Z., Fornaciari, E., McDonnell, M. D., Yaghoobi, M., Cevallos, Y., Tello-Oquendo, L., . . . Gomez, G. A. (2020). The application of deep convolutional neural networks to brain cancer images: a survey. Journal of Personalized Medicine, 10(4), 1-27. DOI Scopus52 WoS27 Europe PMC18 |
| 2020 |
Teo, J. L., Gomez, G. A., Weeratunga, S., Davies, E. M., Noordstra, I., & Yap, A. S. (2020). Caveolae control contractile tension for epithelia to eliminate tumor cells. Developmental Cell, 54(1), 75-91.e7. DOI Scopus52 Europe PMC42 |
| 2020 |
Wu, S. K., Gomez, G. A., Stehbens, S. J., & Smutny, M. (2020). Editorial: Forces in biology - cell and developmental mechanobiology and its implications in disease. Frontiers in Cell and Developmental Biology, 8(598179), 1-3. DOI |
| 2020 |
Teo, J. L., Tomatis, V. M., Coburn, L., Lagendijk, A. K., Schouwenaar, I. M., Budnar, S., . . . Gomez, G. A. (2020). Src kinases relax adherens junctions between the neighbors of apoptotic cells to permit apical extrusion. Molecular biology of the cell, 31(23), 2557-2569. DOI |
| 2020 |
Baratchi, S., Khoshmanesh, K., Cox, C. D., & Gomez, G. A. (2020). Editorial: Mechanobiology: emerging tools and methods. Frontiers in Bioengineering and Biotechnology, 8(289), 1-2. DOI |
| 2019 |
Han, P., Frith, J. E., Gomez, G. A., Yap, A. S., O'Neill, G. M., & Cooper White, J. J. (2019). Five piconewtons: the difference between osteogenic and adipogenic fate choice in human mesenchymal stem cells. ACS Nano, 13(10), 11129-11143. DOI |
| 2019 |
Perrin, S. L., Samuel, M. S., Koszyca, B., Brown, M. P., Ebert, L. M., Oksdath, M., & Gomez, G. A. (2019). Glioblastoma heterogeneity and the tumour microenvironment: implications for preclinical research and development of new treatments. Biochemical Society Transactions, 47(2), 625-638. DOI Scopus127 WoS121 Europe PMC108 |
| 2019 |
Budnar, S., Husain, K. B., Gomez, G. A., Naghibosadat, M., Varma, A., Verma, S., . . . Yap, A. S. (2019). Anillin promotes cell contractility by cyclic resetting of RhoA residence kinetics. Developmental cell, 49(6), 894.e12-906.e12. DOI Scopus75 WoS76 Europe PMC68 |
| 2019 |
Gomez, G. A., Oksdath, M., Brown, M. P., & Ebert, L. M. (2019). New approaches to model glioblastoma in vitro using brain organoids: implications for precision oncology. Translational Cancer Research, 8(Suppl. 6), S606-S611. DOI Scopus10 WoS10 Europe PMC12 |
| 2018 |
Gomez, G. A., Woodcock, J. M., Tergaonkar, V., & Gregory, P. A. (2018). Meeting report: The 8th Barossa Meeting - Cell signaling in cancer medicine in the Barossa Valley, Australia. Cell death and disease, 9(3, article no. 284), 1-3. DOI |
| 2018 |
Boucher, D., Monteleone, M., Coll, R. C., Chen, K. W., Ross, C. M., Teo, J. L., . . . Schroder, K. (2018). Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity. Journal of experimental medicine, 215(3), 827-840. DOI Scopus474 Europe PMC429 |
| 2018 |
Liang, X., Kiru, S., Gomez, G. A., & Yap, A. S. (2018). Regulated recruitment of SRGAP1 modulates RhoA signaling for contractility during epithelial junction maturation. Cytoskeleton, 75(2), 61-69. DOI |
| 2018 |
Frith, J. E., Kusuma, G. D., Carthew, J., Li, F., Cloonan, N., Gomez, G. A., & Cooper White, J. J. (2018). Mechanically-sensitive miRNAs bias human mesenchymal stem cell fate via mTOR signalling. Nature Communications, 9(257), 1-12. DOI Scopus116 Europe PMC99 |
| 2018 |
Coburn, L., Lopez, H., Schouwenaar, I. M., Yap, A. S., Lobaskin, V., & Gomez, G. A. (2018). Role of contact inhibition of locomotion and junctional mechanics in epithelial collective responses to injury. Physical biology, 15(2, article no. 024001), 1-15. DOI |
| 2018 |
Acharya, B. R., Nestor Bergmann, A., Liang, X., Gupta, S., Duszyc, K., Gauquelin, E., . . . Yap, A. S. (2018). A mechanosensitive RhoA pathway that protects epithelia against acute tensile stress. Developmental cell, 47(4), 439-452. DOI |
| 2017 |
Priya, R., Gomez, G. A., Budnar, S., Acharya, B. R., Czirok, A., Yap, A. S., & Neufeld, Z. (2017). Bistable front dynamics in a contractile medium: travelling wave fronts and cortical advection define stable zones of RhoA signaling at epithelial adherens junctions. PLoS computational biology, 13(3, article no. e1005411), 1-19. DOI |
| 2017 |
Lim, Y. W., Lo, H. P., Ferguson, C., Martel, N., Giacomotto, J., Gomez, G. A., . . . Parton, R. G. (2017). Caveolae protect notochord cells against catastrophic mechanical failure during development. Current biology, 27(13), 1968-1981. DOI Scopus62 Europe PMC63 |
| 2017 |
Priya, R., Liang, X., Teo, J. L., Duszyc, K., Yap, A. S., & Gomez, G. A. (2017). ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens. Molecular biology of the cell, 28(1), 12-20. DOI |
| 2017 |
Liang, X., Budnar, S., Gupta, S., Verma, S., Han, S. P., Hill, M. M., . . . Yap, A. S. (2017). Tyrosine dephosphorylated cortactin downregulates contractility at the epithelial zonula adherens through SRGAP1. Nature communications, 8(1, article no. 790), 1-15. DOI Europe PMC26 |
| 2017 |
Acharya, B. R., Wu, S. K., Lieu, Z. Z., Parton, R. G., Grill, S. W., Bershadsky, A. D., . . . Yap, A. S. (2017). Mammalian Diaphanous 1 mediates a pathway for E-cadherin to stabilize epithelial barriers through junctional contractility. Cell reports, 18(12), 2854-2867. DOI |
| 2017 |
Lagendijk, A. K., Gomez, G. A., Baek, S., Hesselson, D., Hughes, W. E., Paterson, S., . . . Hogan, B. M. (2017). Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish. Nature communications, 8(1402), 1-12. DOI |
| 2017 |
Duszyc, K., Gomez, G. A., Schroder, K., Sweet, M. J., & Yap, A. S. (2017). In life there is death: how epithelial tissue barriers are preserved despite the challenge of apoptosis. Tissue barriers, 5(4, article no. e1345353), 1-12. DOI |
| 2016 |
Coburn, L., Lopez, H., Caldwell, B. J., Moussa, E., Yap, C., Priya, R., . . . Gomez, G. A. (2016). Contact inhibition of locomotion and mechanical cross-talk between cell-cell and cell-substrate adhesion determine the pattern of junctional tension in epithelial cell aggregates. Molecular biology of the cell, 27(22), 3436-3448. DOI |
| 2016 |
Michael, M., Liang, X., & Gomez, G. A. (2016). Analysis of myosin II minifilament orientation at epithelial zonula adherens. Bio-protocol, 6(23), 1-12. DOI |
| 2016 |
Michael, M., Meiring, J. C. M., Acharya, B. R., Matthews, D. R., Verma, S., Han, S. P., . . . Yap, A. S. (2016). Coronin 1B reorganizes the architecture of F-actin networks for contractility at steady-state and apoptotic adherens junctions. Developmental cell, 37(1), 58-71. DOI |
| 2015 |
Yap, A. S., Gomez, G. A., & Parton, R. G. (2015). Adherens junctions revisualized: organizing cadherins as nanoassemblies. Developmental cell, 35(1), 12-20. DOI |
| 2015 |
Kubala, M. H., Norwood, S. J., Gomez, G. A., Jones, A., Johnston, W., Yap, A. S., . . . Alexandrov, K. (2015). Mammalian farnesyltransferase ɑ subunit regulates vacuolar protein sorting-associated protein 4A (Vps4A) - dependent intracellular trafficking through recycling endosomes. Biochemical and biophysical research communications, 468(4), 580-586. DOI |
| 2015 |
Liang, X., Gomez, G. A., & Yap, A. S. (2015). Current perspectives on cadherin-cytoskeleton interactions and dynamics. Cell health and cytoskeleton, 7, 11-24. DOI |
| 2015 |
Papadopulos, A., Gomez, G. A., Martin, S., Jackson, J., Gormal, R. S., Keating, D. J., . . . Meunier, F. A. (2015). Activity-driven relaxation of the cortical actomyosin II network synchronizes Munc18-1-dependent neurosecretory vesicle docking. Nature Communications, 6(6297), 1-11. DOI |
| 2015 |
Gomez, G. A., McLachlan, R. W., Wu, S. K., Caldwell, B. J., Moussa, E., Verma, S., . . . Yap, A. S. (2015). An RPTPɑ/Src family kinase/Rap1 signaling module recruits myosin IIB to support contractile tension at apical E-cadherin junctions. Molecular biology of the cell, 26(7), 1249-1262. DOI |
| 2015 |
Noppe, A. R., Roberts, A. P., Yap, A. S., Gomez, G. A., & Neufeld, Z. (2015). Modelling wound closure in an epithelial cell sheet using the cellular Potts model. Integrative biology, 7(10), 1253-1264. DOI |
| 2015 |
Priya, R., Gomez, G. A., Budnar, S., Verma, S., Cox, H. L., Hamilton, N. A., & Yap, A. S. (2015). Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions. Nature cell biology, 17(10), 1282-1293. DOI |
| 2015 |
Wu, S. K., Lagendijk, A. K., Hogan, B. M., Gomez, G. A., & Yap, A. S. (2015). Active contractility at E-cadherin junctions and its implications for cell extrusion in cancer. Cell cycle, 14(3), 315-322. DOI |
| 2014 |
Barry, A. K., Tabdili, H., Muhamed, I., Wu, J., Shashikanth, N., Gomez, G. A., . . . Leckband, D. E. (2014). ɑ-catenin cytomechanics: role in cadherin-dependent adhesion and mechanotransduction. Journal of cell science, 127(8), 1779-1791. DOI |
| 2014 |
Chaudhary, N., Gomez, G. A., Howes, M. T., Lo, H. P., McMahon, K. A., Rae, J. A., . . . Parton, R. G. (2014). Endocytic crosstalk: cavins, caveolins, and caveolae regulate clathrin-independent endocytosis. PLoS biology, 12(4, e1001832), 1-20. DOI |
| 2014 |
Leerberg, J. M., Gomez, G. A., Verma, S., Moussa, E. J., Wu, S. K., Priya, R., . . . Yap, A. S. (2014). Tension-sensitive actin assembly supports contractility at the epithelial zonula adherens. Current biology, 24(15), 1689-1699. DOI |
| 2014 |
Moore, T., Wu, S. K., Michael, M., Yap, A. S., Gomez, G. A., & Neufeld, Z. (2014). Self-organizing actomyosin patterns on the cell cortex at epithelial cell-cell junctions. Biophysical journal, 107(11), 2652-2661. DOI |
| 2014 |
Caldwell, B. J., Lucas, C., Kee, A. J., Gaus, K., Gunning, P. W., Hardeman, E. C., . . . Gomez, G. A. (2014). Tropomyosin isoforms support actomyosin biogenesis to generate contractile tension at the epithelial zonula adherens. Cytoskeleton, 71(12), 663-676. DOI |
| 2014 |
Wu, S. K., Gomez, G. A., Michael, M., Verma, S., Cox, H. L., Lefevre, J. G., . . . Yap, A. S. (2014). Cortical F-actin stabilization generates apical-lateral patterns of junctional contractility that integrate cells into epithelia. Nature cell biology, 16(2), 167-178. DOI |
| 2014 |
Truffi, M., Dubreuil, V., Liang, X., Vacaresse, N., Nigon, F., Han, S. P., . . . Sap, J. (2014). RPTPɑ controls epithelial adherens junctions, linking E-cadherin engagement to c-Src-mediated phosphorylation of cortactin. Journal of cell science, 127(11), 2420-2432. DOI |
| 2014 |
Brooks, A. J., Dai, W., O'Mara, M. L., Abankwa, D., Chhabra, Y., Pelekanos, R. A., . . . Waters, M. J. (2014). Mechanism of activation of protein kinase JAK2 by the growth hormone receptor. Science, 344(6185, article no. 1249783), 710-723. DOI |
| 2014 |
Cameron, A. R., Frith, J. E., Gomez, G. A., Yap, A. S., & Cooper White, J. J. (2014). The effect of time-dependent deformation of viscoelastic hydrogels on myogenic induction and Rac1 activity in mesenchymal stem cells. Biomaterials, 35(6), 1857-1868. DOI |
| 2014 |
Han, S. P., Gambin, Y., Gomez, G. A., Verma, S., Giles, N., Michael, M., . . . Yap, A. S. (2014). Cortactin scaffolds Arp2/3 and WAVE2 at the epithelial zonula adherens. Journal of biological chemistry, 289(11), 7764-7775. DOI |
| 2014 |
Wu, S. K., Budnar, S., Yap, A. S., & Gomez, G. A. (2014). Pulsatile contractility of actomyosin networks organizes the cellular cortex at lateral cadherin junctions. European journal of cell biology, 93(10-12), 396-404. DOI |
| 2013 |
Pedro, M. P., Vilcaes, A. A., Tomatis, V. M., Oliveira, R. G., Gomez, G. A., & Daniotti, J. L. (2013). 2-Bromopalmitate reduces protein deacylation by inhibition of acyl-protein thioesterase enzymatic activities. PLoS One, 8(10, article no. e75232), 1-11. DOI |
| 2013 |
Priya, R., Yap, A. S., & Gomez, G. A. (2013). E-cadherin supports steady-state Rho signaling at the epithelial zonula adherens. Differentiation, 86(3), 133-140. DOI |
| 2013 |
Priya, R., & Gomez, G. A. (2013). Measurement of junctional protein dynamics using Fluorescence Recovery After Photobleaching (FRAP). Bio-protocol, 3(20, article no. e937), 1-11. DOI |
| 2012 |
Ferrari, M. L., Gomez, G. A., & Maccioni, H. J. F. (2012). Spatial organization and stoichiometry of N-Terminal domain-mediated glycosyltransferase complexes in Golgi membranes determined by FRET microscopy. Neurochemical research, 37(6), 1325-1334. DOI |
| 2012 |
Ratheesh, A., Gomez, G. A., Priya, R., Verma, S., Kovacs, E. M., Jiang, K., . . . Yap, A. S. (2012). Centralspindlin and ɑ-catenin regulate Rho signalling at the epithelial zonula adherens. Nature cell biology, 14(8), 818-829. DOI |
| 2012 |
Verma, S., Han, S. P., Michael, M., Gomez, G. A., Yang, Z., Teasdale, R. D., . . . Yap, A. S. (2012). A WAVE2-Arp2/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens. Molecular biology of the cell, 23(23), 4601-4610. DOI |
| 2011 |
Levingston Macleod, J. M., D'Antuono, A., Loureiro, M. E., Casabona, J. C., Gomez, G. A., & Lopez, N. (2011). Identification of two functional domains within the arenavirus nucleoprotein. Journal of virology, 85(5), 2012-2023. DOI |
| 2011 |
Smutny, M., Wu, S. K., Gomez, G. A., Mangold, S., Yap, A. S., & Hamilton, N. A. (2011). Multicomponent analysis of junctional movements regulated by Myosin II isoforms at the epithelial zonula adherens. PLoS One, 6(7, article no. e22458), 1-10. DOI |
| 2011 |
Gomez, G. A., McLachlan, R. W., & Yap, A. S. (2011). Productive tension: force-sensing and homeostasis of cell-cell junctions. Trends in cell biology, 21(9), 499-505. DOI |
| 2010 |
Tomatis, V. M., Trenchi, A., Gomez, G. A., & Daniotti, J. L. (2010). Acyl-protein thioesterase 2 catalizes the deacylation of peripheral membrane-associated GAP-43. PLoS one, 5(11), 1-15. DOI |
| 2009 |
Casabona, J. C., Levingston Macleod, J. M., Loureiro, M. E., Gomez, G. A., Gomez, G. A., & Lopez, N. (2009). The RING domain and the L79 residue of Z protein are involved in both the rescue of nucleocapsids and the incorporation of glycoproteins into infectious chimeric arenavirus-like particles. Journal of virology, 83(14), 7029-7039. DOI |
| 2009 |
Trenchi, A., Gomez, G. A., & Daniott, J. L. (2009). Dual acylation is required for trafficking of growth-associated protein-43 (GAP-43) to endosomal recycling compartment via an Arf6-associated endocytic vesicular pathway. Biochemical journal, 421(3), 357-369. DOI |
| 2007 |
Gomez, G. A., & Daniotti, J. L. (2007). Electrical properties of plasma membrane modulate subcellular distribution of K-Ras. FEBS Journal, 274(9), 2210-2228. DOI |
| 2005 |
Gomez, G. A., & Daniotti, J. L. (2005). H-Ras dynamically interacts with recycling endosomes in CHO-K1 Cells: Involvement of Rab5 and Rab11 in the trafficking of H-Ras to this pericentriolar endocytic compartment. Journal of biological chemistry, 280(41), 34997-35010. DOI |
| - |
Shard, C., Jones, A. C., Fouladzadeh, A., Palethorpe, H. M., Francis, A., Boyle, Y., . . . Fletcher, E. (2025). Novel GABA<sub>A</sub>R antagonists target networked gene hubs at the leading edge in high-grade gliomas. NEURO-ONCOLOGY, 16 pages. DOI WoS2 |