Guangze Yang

School of Chemical Engineering

Faculty of Sciences, Engineering and Technology

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Dr. Guangze Yang is an excellent early-career researcher with extensive experience as a Postdoctoral Research Fellow, specialising in bioinspired materials and nanomedicine. Having obtained a PhD from the Australian Institute for Bioengineering and Nanotechnology (AIBN) at the University of Queensland (UQ), Dr. Yang has made exceptional contributions to the field through his research, academic collaborations, and leadership development.

Dr. Yang's impressive publication record showcases the high impact and recognition of his research, featuring numerous first/corresponding-authored papers in top-tier journals. His work has been published in prestigious journals such as Science Advances, PNAS, Angewandte Chemie, and Advanced Functional Materials, further demonstrating the significance of his contributions to the field. His expertise in bioinspired materials has led to innovative work in nanomedicine, earning him an international patent.

Currently working within the ARC Centre of Excellence for Enabling Eco-Efficient Beneficiation of Minerals, Dr. Yang is also focused on green mineral processing, applying biomolecules such as peptides and proteins to develop sustainable practices in the field. In addition to his research accomplishments, Dr. Yang has successfully conceived multiple research projects, co-organised international academic conferences, and collaborated with esteemed professionals.

Demonstrating outstanding leadership and mentoring skills, Dr. Yang supervises and manages a diverse team of researchers, including PhD students and master's students. As he leads a small team and co-supervises PhD candidates at the University of Adelaide, Dr. Yang remains dedicated to driving advancements in bioinspired materials and nanomedicine while making valuable contributions to the scientific community at large.

My Research
Career
Publications
Teaching
Supervision
Professional Activities
Contact

My research primarily focuses on the development and optimisation of polymeric nanoparticles for drug delivery, aiming to significantly enhance their efficacy and safety. I have pioneered methods for encapsulating water-insoluble drugs in these nanoparticles, achieving exceptionally high drug-loading efficiencies. A key aspect of my work is dedicated to studying drug-release kinetics, utilising innovative methods such as Förster-resonance energy-transfer (FRET). I have also been successful in synthesising silica nanocapsules with high cargo-loading capacity and biomimetic core-shell nanoparticles, contributing to the advancement of more effective drug delivery systems. Additionally, my research explores the potential of block copolymers for drug loading and controlled release. Alongside this, I maintain an interest in employing biomolecules, such as peptides and proteins, in the realm of green mineral processing and beneficiation, with a specific focus on rare earth minerals. This facet of my work aligns with global efforts towards carbon neutrality, energy conservation, emission reduction and water savings.

Appointments

Date Position Institution name
2022 - ongoing Postdoctoral research fellow University of Adelaide
2020 - 2022 Postdoctoral research fellow University of Queensland
Language Competencies

Language Competency
Chinese (Mandarin) Can read, write, speak, understand spoken and peer review
English Can read, write, speak, understand spoken and peer review

Date	Position	Institution name
2022 - ongoing	Postdoctoral research fellow	University of Adelaide
2020 - 2022	Postdoctoral research fellow	University of Queensland

Language	Competency
Chinese (Mandarin)	Can read, write, speak, understand spoken and peer review
English	Can read, write, speak, understand spoken and peer review

Education

Date	Institution name	Country	Title
2015 - 2020	University of Queensland	Australia	PhD
2013 - 2014	University of Queensland	Australia	Master of Engineering Science
2008 - 2012	Tianjin University	China	Bachelor of Chemical Engineering and Technology

Research Interests

Biomedical Engineering Mineral Processing/Beneficiation Nanomaterials Nanomedicine Proteins and Peptides

Journals

Year	Citation
2023	Yang, G., Liu, Y., Jin, S., Hui, Y., Wang, X., Xu, L., . . . Zhao, C. (2023). Phase separation‐induced nanoprecipitation for making polymer nanoparticles with high drug loading. Aggregate, 4(2), 9 pages. DOI Scopus5 WoS1
2023	Weng, Y., Yang, G., Li, Y., Xu, L., Chen, X., Song, H., & Zhao, C. -X. (2023). Alginate-based materials for enzyme encapsulation. Advances in Colloid and Interface Science, 318, 102957-1-102957-15. DOI Scopus6 Europe PMC2
2023	Li, Y., Yang, G., Weng, Y., Xu, L., Hou, F., Devkota, S., & Zhao, C. X. (2023). Exploring biosurfactants as a sustainable alternative to chemical surfactants. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 677, 11 pages. DOI Scopus2
2023	Xu, L., Wang, X., Yang, G., Zhao, Z., Weng, Y., Li, Y., . . . Zhao, C. X. (2023). Development of a concentration-controlled sequential nanoprecipitation for making lipid nanoparticles with high drug loading. Aggregate, 4(6), 14 pages. DOI Scopus2 WoS1
2023	Li, Y., Yang, G., Gerstweiler, L., Thang, S. H. H., & Zhao, C. -X. (2023). Design of Stimuli-Responsive Peptides and Proteins. ADVANCED FUNCTIONAL MATERIALS, 33(7), 2210387-1-2210387-31. DOI Scopus10 WoS2
2022	Zou, D., Wu, Z., Yi, X., Hui, Y., Yang, G., Liu, Y., . . . Zhao, C. -X. (2022). Nanoparticle elasticity regulates the formation of cell membrane-coated nanoparticles and their nano-bio interactions. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 120(1), 1-12. DOI Scopus15 WoS6 Europe PMC6
2022	Liu, Y., Yang, G., Hui, Y., Ranaweera, S., & Zhao, C. -X. (2022). Microfluidic Nanoparticles for Drug Delivery. Small, 18(36), 33 pages. DOI Scopus72 WoS35 Europe PMC19
2022	Tengjisi., Liu, Y., Zou, D., Yang, G., & Zhao, C. (2022). Bioinspired core-shell silica nanoparticles monitoring extra- and intra-cellular drug release. Journal of Colloid and Interface Science, 624, 242-250. DOI Scopus3 WoS3 Europe PMC1
2022	Xu, L., Wang, X., Liu, Y., Yang, G., Falconer, R. J., & Zhao, C. -X. (2022). Lipid Nanoparticles for Drug Delivery. Advanced NanoBiomed Research, 2(2), 1-17. DOI Scopus130 WoS73
2022	Wilson, R. J., Li, Y., Yang, G., & Zhao, C. X. (2022). Nanoemulsions for drug delivery. Particuology, 64, 85-97. DOI Scopus91 WoS55
2022	Tengjisi., Hui, Y., Fan, Y., Zou, D., Talbo, G. H., Yang, G., & Zhao, C. X. (2022). Influence of nanoparticle mechanical property on protein corona formation. Journal of Colloid and Interface Science, 606(2), 1737-1744. DOI Scopus23 WoS15 Europe PMC6
2021	Yang, G., Liu, Y., Teng, J., & Zhao, C. X. (2021). FRET ratiometric nanoprobes for nanoparticle monitoring. Biosensors, 11(12), 505-1-505-24. DOI Scopus18 WoS10 Europe PMC8
2021	Yang, G., Liu, Y., Hui, Y., Tengjisi., Chen, D., Weitz, D. A., & Zhao, C. (2021). Implications of Quenching‐to‐Dequenching Switch in Quantitative Cell Uptake and Biodistribution of Dye‐Labeled Nanoparticles. Angewandte Chemie, 133(28), 15554-15563. DOI
2021	Yang, G., Liu, Y., Hui, Y., Tengjisi., Chen, D., Weitz, D. A., & Zhao, C. (2021). Inside Cover: Implications of Quenching‐to‐Dequenching Switch in Quantitative Cell Uptake and Biodistribution of Dye‐Labeled Nanoparticles (Angew. Chem. Int. Ed. 28/2021). Angewandte Chemie International Edition, 60(28), 15114. DOI
2021	Yang, G., Liu, Y., Hui, Y., Tengjisi., Chen, D., Weitz, D. A., & Zhao, C. (2021). Innentitelbild: Implications of Quenching‐to‐Dequenching Switch in Quantitative Cell Uptake and Biodistribution of Dye‐Labeled Nanoparticles (Angew. Chem. 28/2021). Angewandte Chemie, 133(28), 15242. DOI
2021	Yang, G., Liu, Y., & Zhao, C. X. (2021). Quantitative comparison of different fluorescent dye-loaded nanoparticles. Colloids and Surfaces B: Biointerfaces, 206, 111923-1-111923-9. DOI Scopus5 WoS7 Europe PMC4
2021	Yang, G., Liu, Y., Hui, Y., Tengjisi., Chen, D., Weitz, D. A., & Zhao, C. X. (2021). Implications of Quenching-to-Dequenching Switch in Quantitative Cell Uptake and Biodistribution of Dye-Labeled Nanoparticles. Angewandte Chemie - International Edition, 60(28), 15426-15435. DOI Scopus13 WoS10
2021	Baby, T., Liu, Y., Yang, G., Chen, D., & Zhao, C. X. (2021). Microfluidic synthesis of curcumin loaded polymer nanoparticles with tunable drug loading and pH-triggered release. Journal of Colloid and Interface Science, 594, 474-484. DOI Scopus38 WoS29 Europe PMC7
2021	Yang, M., Gao, Y., Liu, Y., Yang, G., Zhao, C. X., & Wu, K. J. (2021). Integration of microfluidic systems with external fields for multiphase process intensification. Chemical Engineering Science, 234, 116450-1-116450-26. DOI Scopus15 WoS11
2021	Wang, H. F., Liu, Y., Yang, G., & Zhao, C. X. (2021). Macrophage-mediated cancer drug delivery. Materials Today Sustainability, 11-12, 100055-1-100055-6. DOI Scopus16 WoS13
2021	Li, W., Chen, Q., Baby, T., Jin, S., Liu, Y., Yang, G., & Zhao, C. X. (2021). Insight into drug encapsulation in polymeric nanoparticles using microfluidic nanoprecipitation. Chemical Engineering Science, 235, 116468-1-116468-8. DOI Scopus20 WoS11
2021	Tengjisi., Hui, Y., Yang, G., Fu, C., Liu, Y., & Zhao, C. X. (2021). Biomimetic core–shell silica nanoparticles using a dual-functional peptide. Journal of Colloid and Interface Science, 581(A), 185-194. DOI Scopus15 WoS12 Europe PMC4
2020	Han, F. Y., Liu, Y., Kumar, V., Xu, W., Yang, G., Zhao, C. X., . . . Smith, M. T. (2020). Sustained-release ketamine-loaded nanoparticles fabricated by sequential nanoprecipitation. International Journal of Pharmaceutics, 581, 119291-1-119291-7. DOI Scopus33 WoS25 Europe PMC9
2020	Yang, G., Liu, Y., Jin, S., & Zhao, C. X. (2020). Development of core-shell nanoparticle drug delivery systems based on biomimetic mineralization. ChemBioChem, 21(20), 2871-2879. DOI Scopus25 WoS18 Europe PMC4
2020	Zou, D., Yu, L., Sun, Q., Hui, Y., Tengjisi., Liu, Y., . . . Zhao, C. X. (2020). A general approach for biomimetic mineralization of MOF particles using biomolecules. Colloids and Surfaces B: Biointerfaces, 193, 1-9. DOI Scopus31 WoS29 Europe PMC7
2020	Liu, Y., Yang, G., Baby, T., Tengjisi., Chen, D., Weitz, D. A., & Zhao, C. X. (2020). Stable Polymer Nanoparticles with Exceptionally High Drug Loading by Sequential Nanoprecipitation. Angewandte Chemie - International Edition, 59(12), 4720-4728. DOI Scopus96 WoS93
2020	Liu, Y., Yang, G., Jin, S., Zhang, R., Chen, P., Tengjisi., . . . Zhao, C. X. (2020). J-Aggregate-Based FRET Monitoring of Drug Release from Polymer Nanoparticles with High Drug Loading. Angewandte Chemie - International Edition, 59(45), 20065-20074. DOI Scopus38 WoS27 Europe PMC11
2020	Liu, Y., Yang, G., Jin, S., Xu, L., & Zhao, C. X. (2020). Development of high-drug-loading nanoparticles. ChemPlusChem, 85(9), 2143-2157. DOI Scopus137 WoS60 Europe PMC51
2020	Wang, H. F., Liu, Y., Wang, T., Yang, G., Zeng, B., & Zhao, C. X. (2020). Tumor-microenvironment-on-a-chip for evaluating nanoparticle-loaded macrophages for drug delivery. ACS Biomaterials Science and Engineering, 6(9), 5040-5050. DOI Scopus22 WoS16 Europe PMC8
2020	Zou, D., Yu, L., Sun, Q., Hui, Y., Jisi, T., Liu, Y., . . . Zhao, C. -X. (2020). A General Approach for Encapsulation of Biomolecules Using MOF Particles. DOI
2020	Liu, Y., Yang, G., Baby, T., Tengjisi., Chen, D., Weitz, D. A., & Zhao, C. (2020). Stable Polymer Nanoparticles with Exceptionally High Drug Loading by Sequential Nanoprecipitation. Angewandte Chemie, 132(12), 4750-4758. DOI
2020	Liu, Y., Yang, G., Zou, D., Hui, Y., Nigam, K., Middelberg, A. P. J., & Zhao, C. X. (2020). Formulation of nanoparticles using mixing-induced nanoprecipitation for drug delivery. Industrial and Engineering Chemistry Research, 59(9), 4134-4149. DOI Scopus110 WoS83
2020	Hui, Y., Yi, X., Wibowo, D., Yang, G., Middelberg, A. P. J., Gao, H., & Zhao, C. X. (2020). Nanoparticle elasticity regulates phagocytosis and cancer cell uptake. Science Advances, 6(16), 1-11. DOI Scopus129 WoS106 Europe PMC34
2019	Peters, B. C., Wibowo, D., Yang, G. Z., Hui, Y., Middelberg, A. P. J., & Zhao, C. X. (2019). Evaluation of baiting fipronil-loaded silica nanocapsules against termite colonies in fields. Heliyon, 5(8), e02277-1-e02277-10. DOI Scopus13 WoS6 Europe PMC3
2019	Yang, G., Liu, Y., Wang, H., Wilson, R., Hui, Y., Yu, L., . . . Zhao, C. X. (2019). Bioinspired core-shell nanoparticles for hydrophobic drug delivery. Angewandte Chemie - International Edition, 58(40), 14357-14364. DOI Scopus83 WoS55 Europe PMC23
2018	Liu, Y., Hui, Y., Ran, R., Yang, G. Z., Wibowo, D., Wang, H. F., . . . Zhao, C. X. (2018). Synergetic combinations of dual-targeting ligands for enhanced in vitro and in vivo tumor targeting. Advanced Healthcare Materials, 7(15), 1800106-1-1800106-11. DOI Scopus47 WoS41 Europe PMC10
2017	Yang, G., Wibowo, D., Yun, J., Wang, L., Middelberg, A., & Zhao, C. (2017). Biomimetic silica nanocapsules for tunable sustained release and cargo protection. Langmuir, 33(23), 5777-5785. DOI Scopus23 WoS18 Europe PMC4
2017	Wibowo, D., Yang, G., Middelberg, A., & Zhao, C. (2017). Non-chromatographic bioprocess engineering of a recombinant mineralizing protein for the synthesis of silica nanocapsules. Biotechnology and Bioengineering, 114(2), 335-343. DOI Scopus14 WoS12 Europe PMC3

Book Chapters

Year	Citation
2022	Yang, G., Liu, Y., & Zhao, C. (2022). Colloidal Self‐assembly of Block Copolymers for Drug Loading and Controlled Release. In G. Zhao, & Q. Yan (Eds.), Functional Materials from Colloidal Self-assembly (pp. 455-491). Wiley-VCH. DOI Scopus1

Patents

Year Citation
2023 Zhao, C., Yang, G., & Yun, L. (2023). AU/2023902544, SEPARATION OF MINERALS. AU.
2021 Zhao, C., Liu, Y., & Yang, G. (2021). WO/2021/108853, POLYMER NANOPARTICLES. AU.
Theses

Year Citation
- Yang, G. Z. (n.d.). Core-Shell nanomaterials for drug delivery and controlled release.

Year	Citation
2023	Zhao, C., Yang, G., & Yun, L. (2023). AU/2023902544, SEPARATION OF MINERALS. AU.
2021	Zhao, C., Liu, Y., & Yang, G. (2021). WO/2021/108853, POLYMER NANOPARTICLES. AU.

Year	Citation
-	Yang, G. Z. (n.d.). Core-Shell nanomaterials for drug delivery and controlled release.

2022	Course Coordinator	4220_CHEM_ENG_7062, Downstream Bioprocessing
2022	Teacher	4220_CHEM_ENG_7062, Downstream Bioprocessing

Current Higher Degree by Research Supervision (University of Adelaide)

Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
2024	Co-Supervisor	Development of anti-swelling hydrogels for next-generation soft electronics	Doctor of Philosophy	Doctorate	Full Time	Mr Geng Yang
2023	Co-Supervisor	Development of specific metal binding biomolecules for efficient mineral separations	Doctor of Philosophy	Doctorate	Full Time	Ms Yang Yang
2023	Principal Supervisor	Development of bio-inspired cell membrane-coated (BCM) lipid nanoparticles (NPs)	Doctor of Philosophy	Doctorate	Full Time	Mr Moataz Badawy Ali Saper Zewail
2023	Principal Supervisor	A Sustainable Approach for Mineral Processing and Recycling	Doctor of Philosophy	Doctorate	Full Time	Mr Ruilin Zhao
2023	Co-Supervisor	Development of Nanomedicine Libraries with Varied Properties for Drug Delivery	Doctor of Philosophy	Doctorate	Full Time	Mr Yilong Fan
2022	Co-Supervisor	Development of novel bioflocculants for clay particle flocculation	Doctor of Philosophy	Doctorate	Full Time	Mr Matthias Josef Orchard

Other Supervision Activities

Date	Role	Research Topic	Location	Program	Supervision Type	Student Load	Student Name
2021 - 2022	Co-Supervisor	Bioinspired core-shell silica nanomaterials and their nano-bio interactions	University of Queensland	Doctor of Philosophy	Doctorate	Full Time	Tengjisi
2021 - ongoing	Co-Supervisor	Stimuli-responsive soft materials based on biomolecules	University of Queensland	Doctor of Philosophy	Doctorate	Full Time	Yang Li

Committee Memberships

Date	Role	Committee	Institution	Country
2022 - 2022	Member	Future Leaders Committee	ARC Centre for Excellence for Enabling Eco-Efficient Beneficiation of Minerals	Australia
2022 - ongoing	Member	Gender, Equity, Diversity and Inclusion Committee	ARC Centre for Excellence for Enabling Eco-Efficient Beneficiation of Minerals	Australia
2022 - 2022	Member	Exploration Australian Crossdisciplinarity Webinar	Exploration Australian Crossdisciplinarity Webinar	Australia

Memberships

Date	Role	Membership	Country
2021 - ongoing	Member	Australasian Colloid and Interface Society	Australia
2021 - ongoing	Member	Drug Delivery Australia	Australia
2021 - ongoing	Member	Australian Chapter of the Controlled Release Society	Australia

Review, Assessment, Editorial and Advice

Date Title Type Institution Country
2021 - ongoing Novel Reagent Technologies for Arsenic Minerals Thesis Review The University of Queensland Australia

Date	Title	Type	Institution	Country
2021 - ongoing	Novel Reagent Technologies for Arsenic Minerals	Thesis Review	The University of Queensland	Australia

Email: guangze.yang@adelaide.edu.au

Guangze Yang

Appointments

Language Competencies

Education

Research Interests

Journals

Book Chapters

Patents

Theses

Current Higher Degree by Research Supervision (University of Adelaide)

Other Supervision Activities

Committee Memberships

Memberships

Review, Assessment, Editorial and Advice

Connect With Me

External Profiles