Griffith Perkins
Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.
I am an early career researcher with the Centre for Clinical and Experimental Transplantation. I trained in immunology under Professor Toby Coates and Drs Plinio Hurtado and Chris Hope at the University of Adelaide. I currently hold the Mary Overton Early Career Fellowship from the Royal Adelaide Hospital, and appointments with the Adelaide Medical School, SA Pathology, and the International Society of Nephrology. Under the mentorship of Professor Coates, I lead a team of clinicians and scientists undertaking bench-to-bedside translational research to understand and improve protective vaccine responses in immunocompromised populations. Over the last few years, pursuing this goal has taken us from in-depth clinical and molecular immunology to two interventional clinical trials, and has led to excellent collaborations with interstate and international colleagues and people affected by a range of immune-compromising conditions.
My research area is clinical and translational immunology, with a strong grounding in laboratory sciences. Since starting out in 2019, I have presented my research at 8 domestic and 6 international conferences, and have co-authored 33 publications in peer-reviewed journals, including Kidney International, the Journal of Allergy and Clinical Immunology, Blood Cancer Journal, Gut, and Nature Immunology.
Immunosuppression & Vaccine Response
Transplant recipients receive immunosuppressive drugs to prevent their immune system from attacking the 'non-self' transplant. During my PhD I described the severe impact that these drugs have on the antibody and T cell responses to SARS-CoV-2 vaccination in kidney transplant recipients (KTRs), many of whom remain highly vulnerable to COVID-19 and other vaccine-preventable infections (VPIs). In my current fellowship, I am working with a team of two PhD candidates, and local and interstate clinicians, immunologists and virologists, to develop and test strategies to improve long-lived and cross-protective immunity of KTRs against key VPIs - COVID-19, Influenza, Shingles. This work has uncovered two promising targets for intervention to restore patients' T cell and antibody responses: the mechanistic target of rapamycin complex 1 (mTORC1) in T cells, and immunomodulatory microbial species within the gut. We recently completed two multi-centre, randomised controlled trials exploiting these targets in KTRs to improve their response to SARS-CoV-2 booster vaccination.
We are also investigating vaccine responses in people with multiple sclerosis (pwMS), end-stage kidney disease (ESKD), myelofibrosis (MF), and haematopoietic stem cell transplant (HSCT) recipients.
Vaccine Allergy & Tolerance
A small percentage of people experience hypersensitivity reactions to the novel mRNA nanoparticle vaccines against COVID-19. During the pandemic I worked with the Royal Adelaide Hospital Immunology Department and SA Pathology to develop a diagnostic test to stratify individuals at-risk of adverse reaction. We found that the sensitivity of people with allergy to the mRNA vaccines is dependent on the arrangement of polyethylene glycol (PEG) molecules on the surface of the lipid nanoparticle. This property enabled us to massively improve diagnostic sensitivity and reliably diagnose PEG allergy from a blood test.
This collaboration has led to ongoing trials investigating mechanisms and biomarkers of allergic desensitisation in people undergoing venom immunotherapy, and of Bruton's tyrosine kinase inhibitors for the prevention of exercise-induced anaphylaxis.
Centre for Clinical & Experimental Transplantation
The lab under Prof Coates runs a number of other translational research streams that are also available as projects for Honours, M.Phil and PhD students, including:
- Engineered Chimeric Antigen Receptor T regulatory cells (CAR Tregs) as an immunotherapy for type 1 diabetes
- 3-dimensional bioprinting of pancreatic islets and supporting cell types for type 1 diabetes
- Subcutaneous transplantation of pancreatic islets in large animal models and first-in-human trial
- Establishing total pancreatectomy with islet auto-transplantation (TPIAT) as a newly available, reimbursed cure for pancreatitis in Australia
- Patient-derived organoids to model hereditary pancreatitis
- Genetic epidemiology of hereditary pancreatitis in Australia
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Appointments
Date Position Institution name 2023 - ongoing Kidney International Editorial Fellow International Society of Nephrology 2023 - ongoing Mary Overton Early Career Research Fellow Royal Adelaide Hospital 2023 - ongoing Adjunct Senior Lecturer University of Adelaide 2023 - ongoing Affiliate Researcher in Immunology SA Pathology -
Awards and Achievements
Date Type Title Institution Name Country Amount 2024 Award Finalist, Premier's Excellence Award - Emerging Young Talent Government of South Australia Australia - 2023 Fellowship Kidney International Editorial Fellowship International Society of Nephrology United States - 2023 Fellowship Mary Overton Early Career Fellowship Royal Adelaide Hospital Australia $312,000 2023 Award Advanced Immunology School Award for Outstanding Contribution Australian and New Zealand Society for Immunology Australia $250 2022 Research Award Early Career Researcher Award Transplantation Society of Australia and New Zealand Australia Flights & Registration 2022 Research Award Dean’s Commendation for Doctoral Thesis Excellence University of Adelaide Australia - 2022 Research Award President's Prize Transplantation Society of Australia and New Zealand Australia $3,000 2022 Research Award People's Choice Award Transplantation Society of Australia and New Zealand Australia $500 2022 Award Travel grant to attend the 29th International Congress of The Transplantation Society The Transplantation Society Canada $3,500 2022 Award Travel grant to attend the 13th American Transplant Congress Transplantation Society of Australia and New Zealand Australia $2,500 2021 Award Kidney International Reviewer of the Year International Society of Nephrology United States - 2021 Research Award Early Career Researcher Award Transplantation Society of Australia and New Zealand Australia Flights & Registration 2019 Research Award Young Investigator Award Transplantation Society of Australia and New Zealand Australia Flights & Registration 2019 Research Award Mentee-Mentor Award American Society of Transplantation United States $2,500 2019 Award Travel grant to attend the 17th World Congress of the International Pancreas and Islet Transplantation Association Transplantation Society of Australia and New Zealand Australia $2,500 2018 Scholarship Master of Philosophy (No Honours) Scholarship University of Adelaide Australia $94,616 2018 Award Travel grant to attend the Transplantation Science Symposium Asian Regional Meeting Transplantation Society of Taiwan Taiwan, Province of China $750 -
Education
Date Institution name Country Title 2022 - 2022 University of Adelaide Australia PhD 2017 - 2017 University of Adelaide Australia BSc(Adv) 2017 - 2017 University of Adelaide Australia DipLang -
Research Interests
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Journals
Year Citation 2024 Norton, T., Lynn, M. A., Rossouw, C., Abayasingam, A., Perkins, G., Hissaria, P., . . . Lynn, D. J. (2024). B and T cell responses to the BNT162b2 COVID-19 mRNA vaccine are not impaired in germ-free or antibiotic-treated mice. Gut, 73(7), 1222-1224.
Scopus2 Europe PMC12024 Fitzgerald, S. P., Bean, N. G., Falhammar, H., Hoermann, R., Korem Kohanim, Y., Pohlabeln, H., . . . Tomassetti, S. (2024). Population data evidence of interdependence of the limbs of hormonal feedback loops. The Journal of endocrinology, 262(1), 14 pages.
2024 Perkins, G. B., Zuiani, J. D., & Coates, P. T. (2024). The innate immune cells at the heart of kidney allograft rejection. Kidney International, 106(3), 348-350.
2024 Callisto, A., Perkins, G. B., Troelnikov, A., Mhatre, S., Hissaria, P., & Smith, W. (2024). Prevention of exercise-induced anaphylaxis by ibrutinib. Journal of Allergy and Clinical Immunology: In Practice, 12(9), 2503-2505.e2.
2024 Singer, J., Tunbridge, M. J., Shi, B., Perkins, G. B., Chai, C. S., Salehi, T., . . . Chadban, S. J. (2024). Dietary Inulin to Improve SARS-CoV-2 Vaccine Response in Kidney Transplant Recipients: The RIVASTIM-Inulin Randomised Controlled Trial. Vaccines, 12(6), 20 pages.
2024 Perkins, G. B. (2024). Biopsy before transplant: optimizing allocation or fueling discard?. Kidney International, 106(6), 1036-1037.
2024 Lim, A. H. W., Ngoi, B., Perkins, G. B., Wong, S., Whitelock, G., Hurtado, P., . . . Nguyen, N. Q. (2024). Outcomes of Serum Food-Specific Immunoglobulin G<inf>4</inf> to Guide Elimination Diet in Patients with Eosinophilic Esophagitis. American Journal of Gastroenterology, 119(6), 1066-1073.
Scopus3 Europe PMC22024 Baig, M., Nanjappa, N. C., Perkins, G. B., Di Lernia, R., Thiruvenkatarajan, V., & Hissaria, P. (2024). Basophil activation test in the diagnostic workup of perioperative anaphylaxis due to neuromuscular blocking agents: A case series and implications for practice. Anaesthesia and Intensive Care, 52(4), 256-263.
2024 Perkins, G. B., Tunbridge, M. J., Hurtado, P. R., Zuiani, J., Mhatre, S., Yip, K. H., . . . Hissaria, P. (2024). PEGylated liposomes for diagnosis of polyethylene glycol allergy. Journal of Allergy and Clinical Immunology, 154(2), 503-507.e1.
Scopus2 Europe PMC12023 Bell, S., Perkins, G. B., Anandh, U., & Coates, P. T. (2023). COVID and the Kidney: An Update. Seminars in Nephrology, 43(5), 12 pages.
Scopus4 Europe PMC12023 Montarello, N. L., Wong, H. Z., Jeffries, A., Perkins, G. B., Hissaria, P., Stokes, M. B., . . . Bradley, J. (2023). Pfizer BNT 162b2 COVID-19 vaccine–induced fulminant myopericarditis: A case study. Critical Care and Resuscitation, 25(3), 155-157.
Scopus1 Europe PMC12023 Stoler, S., van Hal, S. J., Chadban, S., Le, T., Torzillo, P., Scarlato, R. -M., . . . Marinelli, T. (2023). Protracted COVID-19 pneumonitis early post-ABO incompatible kidney transplantation: Management considerations and the role of whole genome sequencing.. Nephrology (Carlton), 28(11), 639-643.
2023 Perkins, G. B., & Fairchild, R. L. (2023). Linking donor-specific antibody generation with natural killer cells in antibody-mediated kidney graft rejection. Kidney International, 104(4), 644-646.
2023 Perkins, G. B., Grey, S. T., & Coates, P. T. (2023). Taking the A(llorecognition) train: connecting passenger T cells to DSA. Kidney International, 103(2), 246-248.
2023 Sim, B. Z., Sim, B. L., Tunbridge, M. J., Perkins, G. B., Chai, C. S., & Coates, P. T. (2023). SARS-CoV-2 seropositivity in renal transplant patients administered intravenous immunoglobulin. Transplant Infectious Disease, 25(3), 2 pages.
Scopus12023 Zhang, W., Kedzierski, L., Chua, B. Y., Mayo, M., Lonzi, C., Rigas, V., . . . Christensen, B. (2023). Robust and prototypical immune responses toward COVID-19 vaccine in First Nations peoples are impacted by comorbidities.. Nature Immunology, 24(6), 966-978.
Scopus14 WoS2 Europe PMC102023 Asare, P. F., Hurtado, P. R., Tran, H. B., Perkins, G. B., Roscioli, E., & Hodge, S. (2023). Reduction in Rubicon by cigarette smoke is associated with impaired phagocytosis and occurs through lysosomal degradation pathway. Clinical and Experimental Medicine, 23(7), 4041-4055.
2023 Alcheikh, A., Perkins, G. B., Pucar, P. A., Cecchin, A., Chai, C. S., Tunbridge, M., . . . Ross, D. M. (2023). Humoral and cellular immunity to SARS-CoV-2 Ancestral and Omicron BA.5 variants following vaccination in myelofibrosis patients.. Blood Cancer J, 13(1), 4 pages.
Scopus22023 Perkins, G., Tunbridge, M., Chai, C. S., Hope, C., Yeow, A. E. L., Salehi, T., . . . Coates, T. (2023). mTOR inhibition improves the formation of functional T cell memory following COVID-19 vaccination of kidney transplant recipients.
2022 Ali, S. B., Perkins, G., Ryoo, D., Lee, M., Tunbridge, M., Yuson, C., . . . Le, T. T. (2022). AstraZeneca ChAdOx1-S COVID-19 vaccine can be safely administered in patients with EDTA allergy. Allergy, Asthma and Clinical Immunology, 18(1), 4 pages.
Scopus4 WoS1 Europe PMC42022 Perkins, G. B., Tunbridge, M., Salehi, T., Chai, C. S., Kireta, S., Johnston, J., . . . Coates, P. T. (2022). Concurrent vaccination of kidney transplant recipients and close household cohabitants against COVID-19. Kidney International, 101(5), 1077-1080.
Scopus8 WoS5 Europe PMC62022 Tunbridge, M., Perkins, G., Lee, M., Salehi, T., Ryoo, D., Kette, F., . . . Hissaria, P. (2022). COVID vaccination can be performed in patients with a history of allergic reactions to the vaccines or their components: experience from a specialist clinic in South Australia. Internal Medicine Journal, 52(11), 1884-1890.
Scopus12022 Tunbridge, M., Perkins, G. B., Singer, J., Salehi, T., Ying, T., Grubor-Bauk, B., . . . Coates, P. T. (2022). Rapamycin and inulin for booster vaccine response stimulation (RIVASTIM)-rapamycin: study protocol for a randomised, controlled trial of immunosuppression modification with rapamycin to improve SARS-CoV-2 vaccine response in kidney transplant recipients.. Trials, 23(1), 780.
Scopus5 WoS1 Europe PMC32022 Perkins, G. B., Hurtado, P. R., & Hissaria, P. (2022). Basophil reactivity to BNT162b2 in COVID-19 convalescence. Allergy: European Journal of Allergy and Clinical Immunology, 77(12), 3704-3705.
Scopus2 Europe PMC12022 Singer, J., Tunbridge, M., Perkins, G. B., Salehi, T., Ying, T., Wu, H., . . . Chadban, S. J. (2022). Rapamycin and inulin for third-dose vaccine response stimulation (RIVASTIM): Inulin - Study protocol for a pilot, multicentre, randomised, double-blinded, controlled trial of dietary inulin to improve SARS-CoV-2 vaccine response in kidney transplant recipients. BMJ Open, 12(12), 10 pages.
Scopus5 WoS1 Europe PMC22021 Perkins, G. B., Kim, J., & Coates, P. T. (2021). Going rogue: how autoantibodies become pathogenic. Kidney International, 99(4), 800-802.
Scopus12021 Zidan, A. A., Al-Hawwas, M., Perkins, G. B., Mourad, G. M., Stapledon, C. J. M., Bobrovskaya, L., . . . Hurtado, P. R. (2021). Characterization of urine stem cell-derived extracellular vesicles reveals b cell stimulating cargo. International Journal of Molecular Sciences, 22(1), 1-21.
Scopus18 WoS9 Europe PMC132021 Zidan, A. A., Perkins, G. B., Al-Hawwas, M., Elhossiny, A., Yang, J., Bobrovskaya, L., . . . Hurtado, P. R. (2021). Urine stem cells are equipped to provide B cell survival signals. Stem Cells, 39(6), 803-818.
Scopus5 WoS5 Europe PMC52021 Perkins, G., Troelnikov, A., & Hissaria, P. (2021). In reply. Journal of Allergy and Clinical Immunology, 148(3), 902-903.
Scopus12021 Troelnikov, A., Perkins, G., Yuson, C., Ahamdie, A., Balouch, S., Hurtado, P. R., & Hissaria, P. (2021). Basophil reactivity to BNT162b2 is mediated by PEGylated lipid nanoparticles in patients with PEG allergy. Journal of Allergy and Clinical Immunology, 148(1), 91-95.
Scopus76 WoS69 Europe PMC452021 Hope, C. M., Huynh, D., Wong, Y. Y., Oakey, H., Perkins, G. B., Nguyen, T., . . . Barry, S. C. (2021). Optimization of blood handling and peripheral blood mononuclear cell cryopreservation of low cell number samples. International Journal of Molecular Sciences, 22(17), 9129-1-9129-19.
Scopus10 WoS5 Europe PMC82020 Kim, J., Hope, C. M., Gantumur, N., Perkins, G. B., Stead, S. O., Yue, Z., . . . Coates, P. T. (2020). Encapsulation of human natural and induced regulatory T-cells in IL-2 and CCL1 supplemented alginate-GelMA hydrogel for 3D bioprinting. Advanced Functional Materials, 30(15), 2000544-1-2000544-17.
Scopus35 WoS242020 Kim, J., Perkins, G. B., & Coates, P. T. (2020). Evolutionary immunology: how your ancestry can affect your kidney transplant. Kidney International, 98(1), 45-47.
Scopus2 WoS22020 Kim, J., Hope, C. M., Perkins, G. B., Stead, S. O., Scaffidi, J. C., Kette, F. D., . . . Coates, P. T. (2020). Rapamycin and abundant TCR stimulation are required for the generation of stable human induced regulatory T cells. Clinical & Translational Immunology, 9(12), 1-20.
Scopus6 WoS6 Europe PMC42019 Jeffs, L., Peh, C., Nelson, A., Tan, P., Davey, E., Chappell, K., . . . Hurtado, P. (2019). IgM ANCA in healthy individuals and in patients with ANCA-associated vasculitis. Immunologic Research, 67(4-5), 325-336.
Scopus5 WoS4 Europe PMC1 -
Conference Papers
Year Citation 2024 Chai, C. S., Perkins, G. B., Tunbridge, M., Hope, C., Yeow, A., Salehi, T., . . . Coates, T. (2024). Rapamycin diversifies SARS-CoV-2 specific T cell memory with stem cell phenotype in immunosuppressed kidney transplant recipients.. In TRANSPLANTATION Vol. 108 (pp. 89). TURKEY, Istanbul: LIPPINCOTT WILLIAMS & WILKINS. 2023 Lim, A. H., Ngoi, B., Hissaria, P., Perkins, G., Wong, S., Hurtado, P. R., . . . Nguyen, N. Q. (2023). SERUM FOOD-SPECIFIC IGG4-LED TARGETED ELIMINATION DIET IN PATIENTS WITH EOSINOPHILIC ESOPHAGITIS. In GASTROENTEROLOGY Vol. 164 (pp. S90). IL, Chicago: W B SAUNDERS CO-ELSEVIER INC. 2023 Li, W., Corral de Zubielqui, G., & Rao Hill, S. (2023). Typology of Brand NFTs in the Metaverse. In ANZMAC proceeding. The University of Otago - Dunedin - New Zealand. 2023 Zuiani, J., Wu, D., Perkins, G., Grey, S., Drogemuller, C., & Coates, P. T. (2023). Growing pancreatic organoids for hereditary pancreatitis. In Abstracts of the IPITA-IXA-CTRMS Joint Congress 2023, as published in Transplantation Vol. 107 (pp. 35). San Diego, CA, USA: Lippincott Williams & Wilkins.
DOI2023 Gupta, N., Gunawan, I., & Kamineni, R. (2023). Looking beyond the COVID-19 pandemic: Navigating strategic shift for achieving the new normal in the global infrastructure sector. In Proceedings of the Academy of International Business (AIB) Oceania Symposium. Adelaide. 2023 Chai, C., Perkins, G., Yeow, A., Masavuli, M., Mekonnen, Z., Santos, R., . . . Coates, T. (2023). Optimising Adjuvant Effect of Rapamycin to Improve the Immunogenicity of Covid-19 Vaccines. In AMERICAN JOURNAL OF TRANSPLANTATION Vol. 23 (pp. S605). CA, San Diego: ELSEVIER SCIENCE INC. 2022 Lim, A., Hissaria, P., Perkins, G., Wong, S., Whitelock, G., Le, T. -T., . . . Nguyen, N. (2022). Food-specific serum IgG4 in the assessment and management of eosinophilic esophagitis: Its role in guiding food-elimination diet. In JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY Vol. 37 (pp. 191-192). WILEY. 2022 Tunbridge, M. J., Perkins, G., Salehi, T., Grubor-Bauk, B., Sim, B., Ying, T., . . . Coates, P. T. (2022). A Prospective Randomised, Controlled Trial Switching Sirolimus for Mycophenolate to Enhance Immunological Responses to Third Dose COVID-19 Vaccination in Kidney Transplant Recipients with Poor Baseline Humoral Immunity. In AMERICAN JOURNAL OF TRANSPLANTATION Vol. 22 (pp. 1095). ELECTR NETWORK: WILEY. 2022 Singer, J., Tunbridge, M., Salehi, T., Perkins, G., Grubnor-Bauk, B., Sim, B., . . . Chadban, S. J. (2022). A Randomized, Controlled, Double-Blind Trial of Inulin to Boost Response to a Third COVID-19 Vaccine Dose in Kidney Transplant Recipients.. In AMERICAN JOURNAL OF TRANSPLANTATION Vol. 22 (pp. 736). ELECTR NETWORK: WILEY. 2022 Perkins, G. B., Tunbridge, M., Salehi, T., Chai, C., Hope, C. M., Garcia-Valtanen, P., . . . Coates, P. (2022). Sirolimus Use is Associated with an Improved Immune Response to COVID-19 Vaccination in Kidney Transplant Recipients. In AMERICAN JOURNAL OF TRANSPLANTATION Vol. 22 (pp. 873). WILEY. 2022 Perkins, G., Tunbridge, M., Zuiani, J., Ryoo, D., Ahmadie, A., Kette, F., . . . Hissaria, P. (2022). PEGYLATED LIPOSOMAL MEDICATIONS ARE HIGHLY EFFECTIVE REAGENTS FOR THE DIAGNOSIS OF POLYETHYLENE GLYCOL ALLERGY. In INTERNAL MEDICINE JOURNAL Vol. 52 (pp. 7). WILEY. 2021 Tunbridge, M., Perkins, G., Salehi, T., Lee, M., Ryoo, D., Ahmadie, A., . . . Hissaria, P. (2021). EARLY RESULTS OF AN <i>IN VIVO</i> AND <i>IN VITRO</i> ALLERGY TESTING PROTOCOL FOR COVID-19 VACCINATIONS. In INTERNAL MEDICINE JOURNAL Vol. 51 (pp. 14). WILEY. 2020 Stead, S. O., Kim, J., Kette, F. D., Perkins, G. B., & Coates, P. T. H. (2020). SIRNA GENE KNOCKDOWN WITH FUNCTIONALISED POROUS SILICON NANOPARTICLES. In TRANSPLANTATION Vol. 104 (pp. S158). ELECTR NETWORK: LIPPINCOTT WILLIAMS & WILKINS. 2020 Perkins, G., Hope, C. M., Kim, J., Kette, F., Stead, S., Coates, P. T. H., & Hurtado, P. R. (2020). IL-4 REGULATES THE SECRETION OF IL-10 BY HUMAN B CELLS. In TRANSPLANTATION Vol. 104 (pp. S151). ELECTR NETWORK: LIPPINCOTT WILLIAMS & WILKINS. -
Conference Items
Year Citation 2022 Perkins, G., Tunbridge, M., Salehi, T., Chai, C. S., Hope, C. M., Garcia-Valtanen, P., . . . Coates, A. O. T. (2022). MTOR Inhibitors Promote Highly Functional T Cell Immunity in Kidney Transplant Recipients Vaccinated Against COVID-19. Poster session presented at the meeting of TRANSPLANTATION. ELECTR NETWORK: LIPPINCOTT WILLIAMS & WILKINS. 2021 Asare, P., Roscioli, E., Hurtado, P., Tran, H., & Hodge, S. (2021). INHIBITION OF LC3-ASSOCIATED PHAGOCYTOSIS (LAP) IN COPD AND IN RESPONSE TO CIGARETTE SMOKE. Poster session presented at the meeting of RESPIROLOGY. WILEY. 2021 Asare, P. F., Tran, H. B., Hurtado, P. R., Perkins, G. B., Nguyen, P., Jersmann, H., . . . Hodge, S. (2021). Inhibition of LC3-associated phagocytosis in COPD and in response to cigarette smoke. Poster session presented at the meeting of Therapeutic Advances in Respiratory Disease. England: SAGE PUBLICATIONS LTD.
DOI Scopus13 WoS5 Europe PMC82020 Kim, J., Hope, C. M., Scaffidi, J. C., Stead, S. O., Perkins, G. B., Kette, F. D., . . . Coates, P. T. (2020). GENERATION OF STABLE HUMAN INDUCED REGULATORY T-CELLS REQUIRES OPTIMAL RAPAMYCIN CONCENTRATION AND TCR STIMULATION. Poster session presented at the meeting of TRANSPLANTATION. ELECTR NETWORK: LIPPINCOTT WILLIAMS & WILKINS. -
Preprint
Year Citation 2023 Perkins, G., Hope, C., Chai, C. S., Tunbridge, M., Sterling, S., Webb, K., . . . Hissaria, P. (2023). Immune profiling of COVID-19 vaccine responses in people with multiple sclerosis on B cell-depleting therapy.
DOI
Dr Perkins has been awarded a Master of Philosophy (No Honours) Scholarship from the University of Adelaide (awarded to a handful of students university-wide each year) for $94.6K; the Mary Overton ECR Fellowship worth ~$345K; and travel grants and bursaries totalling $17K.
As a CI/CIA he has been awarded $1.5M in competitive grant funding, including from the MRFF (2024-28: $1.32M), the KTDRA (2024: $27.2K), the University of Adelaide (2024: $9.3K) and three related HSCGB project grants investigating mechanisms of desensitisation after allergen immunotherapy (21/22: $46.5K; 22/23: $49.4K; 23/24: $49.4K).
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2024 Co-Supervisor Characterisation of Pancreatic Organoids in Hereditary Pancreatitis and Normal Individuals Doctor of Philosophy Doctorate Full Time Mr James Daniel Zuiani 2024 Co-Supervisor Modulation of the foreign antigen response in solid organ transplantation Doctor of Philosophy Doctorate Full Time Dr Matthew Jack Tunbridge 2024 Co-Supervisor To develop and validate an in vitro diagnostic system to assess insect allergy and monitor outcomes of venom immunotherapy Master of Philosophy (Medical Science) Master Full Time Mrs Shweta Mhatre 2023 Co-Supervisor The Effect of Sirolimus on Enhancing COVID-19 Vaccine Response in Transplant Recipients Doctor of Philosophy Doctorate Full Time Mr Cheng Sheng Chai -
Other Supervision Activities
Date Role Research Topic Location Program Supervision Type Student Load Student Name 2023 - ongoing Co-Supervisor Rapamycin as an adjuvant to enhance vaccine responses in immunocompromised individuals University of Adelaide - Doctorate - Cheng Sheng Chai 2021 - 2021 Co-Supervisor Immunogenicity of COVID-19 Vaccines In South Australian Kidney Transplant Recipients University of Adelaide - Honours - Cheng Sheng Chai
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Committee Memberships
Date Role Committee Institution Country 2020 - ongoing Member Early Career Researcher Committee Transplantation Society of Australia and New Zealand Australia -
Memberships
Date Role Membership Country 2023 - ongoing Member Australiasian Society of Clinical Immunology and Allergy Australia 2023 - ongoing Member International Society of Nephrology Belgium 2019 - ongoing Member American Society of Transplantation United States 2019 - ongoing Member Australian and New Zealand Society for Immunology Australia 2018 - ongoing Member The Transplantation Society Canada 2018 - ongoing Member Transplantation Society of Australia and New Zealand Australia -
Community Engagement
Date Title Engagement Type Institution Country 2023 - ongoing Social Media Representative Scientific Community Engagement Transplantation Society of Australia and New Zealand Australia -
Editorial Boards
Date Role Editorial Board Name Institution Country 2024 - ongoing Board Member Scientific Reports Nature Portfolio Germany 2022 - ongoing Board Member Kidney International International Society of Nephrology United States -
Offices Held
Date Office Name Institution Country 2023 - ongoing Kidney International Editorial Fellow Kidney International United States
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