Gohar Shaghayegh

Gohar Shaghayegh

Adelaide Medical School

Faculty of Health and Medical Sciences

Cancer Cell Biology

Applied Immunology

Infectious Disease

Clinical Microbiology

Cell and Molecular Biology

  • Appointments
    Date Position Institution name
    2022 - ongoing Postdoctoral researcher University of Adelaide
    2013 - 2014 Research assistant University of Malaya
    2008 - 2011 Research assistant Quaem medical centre

  • Awards and Achievements
    Date Type Title Institution Name Country Amount
    2020 Award Best Oral Presenter (Junior PhD Student) The Queen Elizabeth Hospital (TQEH), and The University of Adelaide Australia $1000
    2020 Achievement Finalist in Faculty of health and medical sciences 3MT competition Faculty of health & medical sciences, The University of Adelaide Australia -
    2018 Award The Hospital Research Foundation (THRF) postgraduate Research Scholarship (2018-2021) Basil Hetzel Institute for Translational Research, The Queen Elizabeth Hospital Australia -
    2018 Award The University of Adelaide Full Fee Scholarship (2018-2021) The University of Adelaide Australia -
    2013 Award The University of Malaya Research Grant (UMRG) scholarship-Research assistantship The University of Malaya Malaysia RM 19000
    2004 Achievement Distinguished student by National Organization of Educational Testing The University of Tehran Iran, Islamic Republic of -
    2004 Award The University of Tehran Full scholarship for undergraduate studies in cell and molecular biology (2004-2008) The University of Tehran Iran, Islamic Republic of -

  • Language Competencies
    Language Competency
    English Can read, write, speak, understand spoken and peer review
    Persian Can read, write, speak, understand spoken and peer review
    Turkish Can speak and understand spoken

  • Education
    Date Institution name Country Title
    2018 - 2022 University of Adelaide Australia PhD in Medicine & Surgery
    2013 - 2016 University of Malaya Malaysia Master of Dental Science-Cell Biotechnology
    2004 - 2008 University of Tehran Iran Bachelor of Science in Cell and Molecular Biology

  • Research Interests
    Applied Immunology Biochemistry & Molecular Biology Cancer Cell Biology Clinical Microbiology Infectious Diseases Tumour Immunology Immunology and Infection Innovative Therapeutics

  • Journals
    Year Citation
    2023 Shaghayegh, G., Cooksley, C., Bouras, G. S., Panchatcharam, B. S., Idrizi, R., Jana, M., . . . Vreugde, S. (2023). Chronic rhinosinusitis patients display an aberrant immune cell localization with enhanced S aureus biofilm metabolic activity and biomass. Journal of Allergy and Clinical Immunology, 151(3), 723-736.e16.
    DOI Scopus2
    2023 Shaghayegh, G., Cooksley, C., Bouras, G., Nepal, R., Houtak, G., Panchatcharam, B. S., . . . Vreugde, S. (2023). Staphylococcus aureus biofilm properties and chronic rhinosinusitis severity scores correlate positively with total CD4+ T-cell frequencies and inversely with its Th1, Th17 and regulatory cell frequencies. Immunology, 170(1), 120-133.
    DOI
    2023 Shaghayegh, G., Cooksley, C., Bouras, G., Houtak, G., Nepal, R., Psaltis, A. J., . . . Vreugde, S. (2023). S. aureus biofilm metabolic activity correlates positively with patients’ eosinophil frequencies and disease severity in chronic rhinosinusitis. Microbes and Infection, 105213--105213.
    DOI
    2023 Houtak, G., Bouras, G., Nepal, R., Shaghayegh, G., Cooksley, C., Psaltis, A. J., . . . Vreugde, S. (2023). The intra-host evolutionary landscape and pathoadaptation of persistent <i>Staphylococcus aureus</i> in chronic rhinosinusitis.. Microbial genomics, 9(11).
    DOI
    2022 Mahnaz, R., Harrison, B., Hon, K., Gohar, S., Hadi, R., Aaron, F. K., . . . Sarah, V. (2022). Characterization of human nasal organoids from chronic rhinosinusitis patients.. Biology open, 11(8), 1-8.
    DOI Scopus1 WoS1
    2022 Shaghayegh, G., Cooksley, C., Ramezanpour, M., Wormald, P. -J., Psaltis, A. J., & Vreugde, S. (2022). Chronic Rhinosinusitis, S. aureus Biofilm and Secreted Products, Inflammatory Responses, and Disease Severity. Biomedicines, 10(6), 1-28.
    DOI Scopus8 WoS5 Europe PMC1
    2021 Feizi, S., Javadiyan, S., Cooksley, C. M., Shaghayegh, G., Psaltis, A. J., Wormald, P., & Vreugde, S. (2021). Green synthesized colloidal silver is devoid of toxic effects on primary human nasal epithelial cells in vitro. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 157, 112606-1-112606-10.
    DOI Scopus3 WoS2 Europe PMC1
    2021 Nepal, R., Houtak, G., Shaghayegh, G., Bouras, G., Shearwin, K., Psaltis, A. J., . . . Vreugde, S. (2021). Prophages encoding human immune evasion cluster genes are enriched in Staphylococcus aureus isolated from chronic rhinosinusitis patients with nasal polyps. Microbial Genomics, 7(12), 1-19.
    DOI Scopus10 WoS8 Europe PMC8
    2020 Jayash, S. N., Al-Namnam, N. M., & Shaghayegh, G. (2020). Osteoprotegerin (OPG) pathways in bone diseases and its application in therapeutic perspectives. Biointerface Research in Applied Chemistry, 10(2), 5193-5200.
    DOI Scopus8 WoS7
    2020 Smith, A., Shaghayegh, G., Menzies, A. M., & Roberts-Thomson, R. (2020). Duration of immunotherapy - should we continue ad infinitum?. Intern Med J, 50(7), 865-868.
    DOI Scopus6 WoS6 Europe PMC4
    2019 Al-Afifi, N. A., Alabsi, A. M., Shaghayegh, G., Ramanathan, A., Ali, R., Alkoshab, M., & Bakri, M. M. (2019). The in vitro and in vivo antitumor effects of Dracaena cinnabari resin extract on oral cancer. Archives of Oral Biology, 104, 77-89.
    DOI Scopus8 WoS7 Europe PMC3
    2017 Shaghayegh, G., Alabsi, A. M., Ali-Saeed, R., Ali, A. M., Vincent-Chong, V. K., Ismail, N. H., . . . Zain, R. B. (2017). Effects of damnacanthal and nordamnacanthal on proliferation, apoptosis, and migration of oral squamous cell carcinoma cells. Asian Pacific Journal of Cancer Prevention, 18(12), 3333-3341.
    DOI Scopus13 Europe PMC9
    2016 Shaghayegh, G., Alabsi, A. M., Ali-Saeed, R., Ali, A. M., Vincent-Chong, V. K., & Zain, R. B. (2016). Cell cycle arrest and mechanism of apoptosis induction in H400 oral cancer cells in response to Damnacanthal and Nordamnacanthal isolated from Morinda citrifolia. Cytotechnology, 68(5), 1999-2013.
    DOI Scopus15 WoS10 Europe PMC7
    2013 Sadeghian, M. H., Yazdi, S. A. T., Ayatollahi, H., Keramati, M. R., Ghazvini, K., Rezai, A. R., . . . Shaghayegh, G. (2013). Is there any relationship between Chlamydophila pneumoniae and coronary atherosclerosis among Iranians?. Nigerian medical journal : journal of the Nigeria Medical Association, 54(1), 40-44.
    DOI Europe PMC3
    2013 Sadeghian, M. H., Yazdi, S. A. T., Ayatollahi, H., Ghazvini, K., Keramati, M. R., Karimiani, E. G., . . . Shaghayegh, G. (2013). Absence of Helicobacter pylori infection in coronary atherosclerosis disease in Northeast of Iran. Artery Research, 7(3-4), 211-215.
    DOI Scopus1 WoS1
    2013 Sadeghian, M. H., Mohammadnia Avval, M., Ayatollahi, H., Keramati, M. R., Memar, B., Amel Jamedar, S., . . . Shaghayegh, G. (2013). Is There Any Relationship between Human Herpesvirus-8 and Multiple Myeloma?. Lymphoma, 2013, 1-5.
    DOI
    2011 Sadeghian, M. H., Ayatollahi, H., Keramati, M. R., Memar, B., Jamedar, S. A., Avval, M. M., . . . Shaghayegh, G. (2011). The association of Epstein-Barr Virus infection with multiple myeloma. Indian Journal of Pathology and Microbiology, 54(4), 720-724.
    DOI Scopus19 WoS17 Europe PMC12

-Cell Culture Methods

-Microbiological techniques

-Cancer research methods

-Flow cytometry

-Scientific presentation and writing

-Biostatistics

  • Mentoring
    Date Topic Location Name
    2020 - 2021 Antimicrobial susceptibility analysis of Staphylococcus aureus The University of Adelaide Cate Cheney (Summer student)

  • Committee Memberships
    Date Role Committee Institution Country
    2019 - 2020 Member Basil Hetzel institute Management Committee, The Queen Elizabeth Hospital The Queen Elizabeth Hospital and The University of Adelaide Australia

  • Memberships
    Date Role Membership Country
    2019 - ongoing Member Australian and New Zealand Society for Immunology Australia
    2019 - 2020 Representative Student representative at Basil Hetzel Institute, The University of Adelaide Australia
    2019 - ongoing Member Expert Cytometry’s Mastery Class United States

  • Event Participation
    Date Event Name Event Type Institution Country
    2021 - 2021 Together, fight campaign from The Hospital Research Foundation (THRF) Group Fundraiser The Hospital Research Foundation (THRF) Group Australia
    2020 - ongoing The longest table (fork cancer) from The Hospital Research Foundation (THRF) Group Fundraiser Basil Hetzel Institute and The Hospital Research Foundation Australia
    2019 - ongoing The longest table (fork cancer) Fundraiser Basil Hetzel Institute and The Hospital Research Foundation Australia

  • Presentation
    Date Topic Presented at Institution Country
    2020 - ongoing The relationship between bacterial biofilm properties and inflammation in chronic rhinosinusitis TQEH Research Expo, Basil Hetzel Institute for Translational Research, The Queen Elizabeth Hospital The University of Adelaide Australia
    2020 - ongoing Alteration of B cell phenotype in CRS patients is correlated with the disease severity and the metabolic activity of Staphylococcus aureus biofilm 2020 Florey Postgraduate Research Conference The University of Adelaide Australia
    2020 - ongoing Progress in PhD project: Inflammatory markers analysis in CRS patients NT Surgery Group- Otolaryngology–Head and Neck Surgery, The Queen Elizabeth Hospital The University of Adelaide Australia
    2020 - ongoing Ph.D. second-year talk: Chronic Rhinosinusitis and S. aureus Basil Hetzel Institute, The Queen Elizabeth Hospital The University of Adelaide Australia
    2020 - ongoing Immunophenotypic analysis of B cells in CRS patients ENT Surgery Group-Otolaryngology–Head and Neck Surgery, The Queen Elizabeth Hospital The University of Adelaide Australia
    2019 - ongoing Key inflammatory markers of T cells in CRS patients TQEH Research Expo, Basil Hetzel Institute for Translational Research, The Queen Elizabeth Hospital The University of Adelaide Australia
    2019 - ongoing PhD proposal defence Basil Hetzel Institute for Translational Research, The Queen Elizabeth Hospital The University of Adelaide Australia
    2016 - ongoing MSc. Viva voce: Mechanism of apoptosis induction in head and neck squamous carcinoma (HNSCC) cell lines in response to Damnacanthal, Nordamnacanthal, and Dracaena cinnabari Balf. f Faculty of Dentistry, The University of Malaya The University of Malaya Malaysia
    2015 - ongoing MSc Candidature Defence: Mechanism of apoptosis induction in head and neck squamous carcinoma (HNSCC) cell lines in response to Damnacanthal, Nordamnacanthal, and Dracaena cinnabari Balf. f Dental Library, Faculty of Dentistry, The University of Malaya The University of Malaya Malaysia
    2015 - ongoing MSc Proposal Defence Dental Library, Faculty of Dentistry, The University of Malaya The University of Malaya Malaysia
    2014 - 2014 Mechanism of apoptosis induction in oral cancer cells in response to Damnacanthal and Nordamnacanthal from Morinda citrifolia International Conference on Pharmaceutical, Medical & Environmental Health (IPharME) The University of Malaya Malaysia
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