Professor Frank Grutzner

Frank Grutzner
Genetics Lecturer
School of Biological Sciences
Faculty of Sciences

Professor Frank Grützner received his PhD at the Max Planck Institute for Molecular Genetics, Berlin in 2001. In the same year he moved to the Australian National University where he led and international team that resolved the longstanding controversy about the complex sex chromosome system in the platypus. In 2005 he moved to the University of Adelaide, where he is an ARC Australian Research Fellow and group leader at the School of Biological Sciences. Dr Grutzner has worked in the field of comparative genome biology in many different species and published extensively in leading international journals including Nature, Nature Genetics and Science. For the past 10 years he has been instrumental in establishing monotremes as evolutionary model for research in comparative genomics.

He has won several awards for his research including the Eppendorf Medal for the Young Australian Investigator (2005) and the Tall Poppy Science Award (2007/8). His research has been supported by competitive ARC research fellowships and grants since 2003. Dr Grutzner is an associate editor for BMC Genomics and has served on NHMRC grant review panels. He is currently a member of the ARC college of experts.

Connect With Me

Professor Frank Grutzner

Professor Frank Grützner received his PhD at the Max Planck Institute for Molecular Genetics, Berlin in 2001. In the same year he moved to the Australian National University where he led and international team that resolved the longstanding controversy about the complex sex chromosome system in the platypus. In 2005 he moved to the University of Adelaide, where he is an ARC Australian Research Fellow and group leader at the School of Biological Sciences. Dr Grutzner has worked in the field of comparative genome biology in many different species and published extensively in leading international journals including Nature, Nature Genetics and Science. For the past 10 years he has been instrumental in establishing monotremes as evolutionary model for research in comparative genomics.

He has won several awards for his research including the Eppendorf Medal for the Young Australian Investigator (2005) and the Tall Poppy Science Award (2007/8). His research has been supported by competitive ARC research fellowships and grants since 2003. Dr Grutzner is an associate editor for BMC Genomics and has served on NHMRC grant review panels. He is currently a member of the ARC college of experts.

Comparative Genome Biology

Our research aims to understand how different animal genomes evolved, how they are organised and how this effects their function. We use our results to better understand genome evolution and function but also to apply our novel insights to human disease and animal conservation. Our main species of interest are the iconic egg-laying mammals, the duck-billed platypus and short-beaked echidna. As the oldest surviving mammalian lineage these extraordinary animals provide valuable insights into mammalian evolution and human disease.

current research areas:

Sex chromosome evolution and function in mammals

Evolution and function of genes involved in metabolic control

Evolution of monoallelic gene expression and genomic imprinting

Evolution of non coding RNAs in reproduction

Function of the piRNA pathway in ovarian cancer

Application and development of moelcuar tools to aid monotreme field biolgy, conservation and captive breeding

Investigating mosquitofish sex determination as a tool for pest animal control

 

The Monotreme Resource Centre

Egg-laying mammals feature extraordinary biology and are the oldest surviving mammal. Platypus and echidna caputure the interest of researchers worl wide ever since the first specimen were send to England in 1798. Access to material from these animals has always been the limiting factor for research to better understand the biology of these animals. Since 2001 we have assembled a world-wide unique collection of well over 1000 specimen of tissues from platypus and echidna which are availbale for research. This has resulted in breakthrough research including monotremes and new datasets that are available to the research community to use to better understand mammalian evolution. Please contact us for more information about the collection and collaborative opportunities.

Appointments

Date Position Institution name
2013 Professor (ARC fellow) The University of Adelaide
2005 ARC research fellow The University of Adelaide
2001 - 2004 Researcher Australian National University
1997 - 2016 PhD candidate Max Planck Institute of Molecular Genetics

Awards and Achievements

Date Type Title Institution Name Amount
2011 - 2016 ARC Fellowship (ARF) Australian Research Council
2010 Finalist: Scopus Award for the Young Australian Researcher (Biological Sciences)
2008 Research Career Development ECR Achievement award (School of Molecular and Biomedical Science) The University of Adelaide
2008 Certificate of merit for research excellence, Faculty of Science, University of Adelaide The University of Adelaide
2007 - 2008 Tall Poppy Science Award Australian Institute of Policy and Science
2006 - 2011 ARC Fellowship (ARF) Australian Research Council
2005 Eppendorf Medal for the Young Australian Investigator Eppendorf

Journals

Year Citation
2017 Casey, A., Daish, T., Barbero, J. & Grützner, F. (2017). Differential cohesin loading marks paired and unpaired regions of platypus sex chromosomes at prophase i. Scientific Reports, 7, 1, -. 10.1038/s41598-017-04560-5
2016 Tsend-Ayush, E., He, C., Myers, M., Andrikopoulos, S., Wong, N., Sexton, P. ... Grutzner, F. (2016). Monotreme glucagon-like peptide-1 in venom and gut: One gene - Two very different functions. Scientific Reports, 6, 1, -. 10.1038/srep37744
2015 Lynch, V. J., Nnamani, M. C., Kapusta, A., Brayer, K., Plaza, S. L., Mazur, E. C. ... Wagner, G. P. (2015). Ancient transposable elements transformed the uterine regulatory landscape and transcriptome during the evolution of mammalian pregnancy. Cell Reports, 10, 4, 551-562. 10.1016/j.celrep.2014.12.052
2015 He, C., Myers, M., Forbes, B. & Grützner, F. (2015). Immunohistochemical analysis of pancreatic islets of platypus (Ornithorhynchus anatinus) and echidna (Tachyglossus aculeatus ssp.). Journal of Anatomy, 226, 4, 373-380. 10.1111/joa.12279
2015 Casey, A., Daish, T. & Grutzner, F. (2015). Identification and characterisation of synaptonemal complex genes in monotremes. Gene, 567, 2, 146-153. 10.1016/j.gene.2015.04.089
2015 Daish, T., Casey, A. & Grutzner, F. (2015). Lack of sex chromosome specific meiotic silencing in platypus reveals origin of MSCI in therian mammals. BMC Biology, 13, 1, 106-1-106-13. 10.1186/s12915-015-0215-4
2014 Lim, S., Ricciardelli, C., Oehler, M., De Arao Tan, I., Russell, D. & Grützner, F. (2014). Overexpression of piRNA pathway genes in epithelial ovarian cancer. R. Samant (Ed.). PLoS One, 9, 6, e99687-1-e99687-11. 10.1371/journal.pone.0099687
2014 Necsulea, A., Soumillon, M., Warnefors, M., Liechti, A., Daish, T., Zeller, U. ... Kaessmann, H. (2014). The evolution of lncRNA repertoires and expression patterns in tetrapods. Nature, 505, 7485, 635-640. 10.1038/nature12943
2014 Cortez, D., Marin, R., Toledo-Flores, D., Froidevaux, L., Liechti, A., Waters, P. ... Kaessmann, H. (2014). Origins and functional evolution of Y chromosomes across mammals. Nature, 508, 7497, 488-493. 10.1038/nature13151
2013 He, C., Tsend-Ayush, E., Myers, M., Forbes, B. & Grutzner, F. (2013). Changes in the ghrelin hormone pathway maybe part of an unusual gastric system in monotremes. General and Comparative Endocrinology, 191, 74-82. 10.1016/j.ygcen.2013.06.003
2013 Zemann, A., Churakov, G., Donnellan, S., Grutzner, F., Zhao, F., Brosius, J. & Schmitz, J. (2013). Ancestry of the Australian termitivorous numbat. Molecular Biology and Evolution, 30, 5, 1041-1045. 10.1093/molbev/mst032
2013 Long, H., Sims, D., Heger, A., Blackledge, N., Kutter, C., Wright, M. ... Klose, R. (2013). Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates. eLife, 2013, 2, e00348-1-e00348-19. 10.7554/eLife.00348#sthash.otVB3Ndl.dpuf
2013 Chang, C., Semyonov, J., Cheng, P., Huang, S., Park, J., Tsai, H. ... Hsu, S. (2013). Widespread divergence of the CEACAM/PSG genes in vertebrates and humans suggests sensitivity to selection. PLoS One, 8, 4, 1-13. 10.1371/journal.pone.0061701
2013 Ayers, K., Davidson, N., Demiyah, D., Roeszler, K., Grutzner, F., Sinclair, A. ... Smith, C. (2013). RNA sequencing reveals sexually dimorphic gene expression before gonadal differentiation in chicken and allows comprehensive annotation of the W-chromosome. Genome Biology (Print): biology for the post-genomic era, 14, 3, -. 10.1186/gb-2013-14-3-r26
2013 Lim, S., Tsend-Ayush, E., Kortschak, R., Jacob, R., Ricciardelli, C., Oehler, M. & Grutzner, F. (2013). Conservation and expression of piRNA pathway genes in male and female adult gonad of amniotes. Biology of Reproduction, 89, 6, 1-13. 10.1095/biolreprod.113.111211
2012 Tsend-Ayush, E., Kortschak, R., Bernard, P., Lim, S., Ryan, J., Rosenkranz, R. ... Grutzner, F. (2012). Identification of mediator complex 26 (Crsp7) gametologs on platypus X1 and Y5 sex chromosomes: a candidate testis-determining gene in monotremes?. Chromosome Research, 20, 1, 127-138. 10.1007/s10577-011-9270-z
2012 Williams, C., Hoppe, H., Rezgui, D., Strickland, M., Forbes, B., Grutzner, F. ... Hassan, A. (2012). An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution. Science, 338, 6111, 1209-1213. 10.1126/science.1228633
2012 Julien, P., Brawand, D., Soumillon, M., Necsulea, A., Liechti, A., Schutz, F. ... Kaessmann, H. (2012). Mechanisms and evolutionary patterns of mammalian and avian dosage compensation. PLoS Biology, 10, 5, 1-20. 10.1371/journal.pbio.1001328
2012 Hrdlickova, R., Nehyba, J., Lim, S., Grutzner, F. & Bose, H. (2012). Insights into the evolution of mammalian telomerase: Platypus TERT shares similarities with genes of birds and other reptiles and localizes on sex chromosomes. BMC Genomics, 13, 1, 2-38. 10.1186/1471-2164-13-216
2011 Brawand, D., Soumillon, M., Necsulea, A., Julien, P., Csardi, G., Harrigan, P. ... Kaessmann, H. (2011). The evolution of gene expression levels in mammalian organs. Nature, 478, 7369, 343-350. 10.1038/nature10532
2009 Tsend-Ayush, E., Lim, S., Pask, A., Mohd Hamdan, D., Renfree, M. & Grutzner, F. (2009). Characterisation of ATRX, DMRT1, DMRT7 and WT1 in the platypus (Ornithorhynchus anatinus). Reproduction Fertility and Development, 21, 8, 985-991. 10.1071/RD09090
2009 Daish, T. & Grutzner, F. (2009). Location, Location, Location! Monotremes Provide Unique Insights into the Evolution of Sex Chromosome Silencing in Mammals. DNA and Cell Biology, 28, 2, 91-100. 10.1089/dna.2008.0818
2009 Ivell, R. & Grutzner, F. (2009). Evolution and Male Fertility: Lessons from the Insulin-Like Factor 6 Gene (Insl6). Endocrinology, 150, 9, 3986-3990. 10.1210/en.2009-0691
2009 Kortschak, R., Tsend-Ayush, E. & Grutzner, F. (2009). Analysis of SINE and LINE repeat content of Y chromosomes in the platypus, Ornithorhynchus anatinus. Reproduction Fertility and Development, 21, 8, 964-975. 10.1071/RD09084
2009 Tsend-Ayush, E., Dodge, N., Mohr, J., Casey, A., Himmelbauer, H., Kremitzki, C. ... Grutzner, F. (2009). Higher-order genome organization in platypus and chicken sperm and repositioning of sex chromosomes during mammalian evolution. Chromosoma, 118, 1, 53-69. 10.1007/s00412-008-0177-1
2009 Ho, K., Deakin, J., Wright, M., Marshall Graves, J. & Grutzner, F. (2009). Replication asynchrony and differential condensation of X chromosomes in female platypus (Ornithorhynchus anatinus). Reproduction Fertility and Development, 21, 8, 952-963. 10.1071/RD09099
2009 Daish, T., Casey, A. & Grutzner, F. (2009). Platypus chain reaction: directional and ordered meiotic pairing of the multiple sex chromosome chain in Ornithorhynchus anatinus. Reproduction Fertility and Development, 21, 8, 976-984. 10.1071/RD09085
2009 Warren, W. & Grutzner, F. (2009). The enigma of the platypus genome. Australian Journal of Zoology, 57, 3-4, 157-165. 10.1071/ZO09051
2008 Warren, W., Hillier, L., Graves, J., Birney, E., Ponting, C., Grutzner, F. ... Chen, L. (2008). Genome analysis of the platypus reveals unique signatures of evolution. Nature, 453, 7192, 175-184. 10.1038/nature06936
2008 Wakefield, M., Anderson, M., Chang, E., Wei, K., Kaul, R., Marshall-Graves, J. ... Deeb, S. (2008). Cone visual pigments of monotremes: Filling the phylogenetic gap. Visual Neuroscience, 25, 3, 257-264. 10.1017/S0952523808080255
2008 Grutzner, F., Nixon, B. & Jones, R. (2008). Reproductive biology in egg-laying mammals. Sexual Development, 2, 3, 115-127. 10.1159/000143429
2008 Warren, W., Hillier, L., Marshall Graves, J., Birney, E., Ponting, C., Grützner, F. ... Chen, L. (2008). Genome analysis of the platypus reveals unique signatures of evolution (Nature (2008) 453, (175-183)). Nature, 455, 7210, 256-. 10.1038/nature07253
2008 Schmitz, J., Zemann, A., Churakov, G., Kuhl, H., Grutzner, F., Reinhardt, R. & Brosius, J. (2008). Retroposed SNOfall - A mammalian-wide comparison of platypus snoRNAs. Genome Research, 18, 6, 1005-1010. 10.1101/gr.7177908
2008 Murchison, E., Kheradpour, P., Sachidanandam, R., Smith, C., Hodges, E., Xuan, Z. ... Hannon, G. (2008). Conservation of small RNA pathways in platypus. Genome Research, 18, 6, 995-1004. 10.1101/gr.073056.107
2008 Veyrunes, F., Waters, P., Miethke, P., Rens, W., McMillan, D., Alsop, A. ... Graves, J. (2008). Bird-like sex chromosomes of platypus imply recent origin of mammal sex chromosomes. Genome Research, 18, 6, 965-973. 10.1101/gr.7101908
2008 Niwa, H., Sekita, Y., Tsend-Ayush, E. & Grutzner, F. (2008). Platypus Pou5f1 reveals the first steps in the evolution of trophectoderm differentiation and pluripotency in mammals. Evolution & Development, 10, 6, 671-682. 10.1111/j.1525-142X.2008.00280.x
2008 Ordonez, G., Hillier, L., Warren, W., Grutzner, F., Lopez-Otin, C. & Puente, X. (2008). Loss of genes implicated in gastric function during platypus evolution. Genome Biology (Online Edition), 9, 5, R81-1-R81-11. 10.1186/gb-2008-9-5-r81
2007 Dohm, J., Tsend-Ayush, E., Reinhardt, R., Grutzner, F. & Himmelbauer, H. (2007). Disruption and pseudoautosomal localization of the major histocompatibility complex in monotremes. Genome Biology (Online Edition), 8, 8, R175-1-R175-16. 10.1186/gb-2007-8-8-r175
2007 Wallis, M., Delbridge, M., Pask, A., Alsop, A., Grutzner, F., O'Brien, P. ... Graves, J. (2007). Mapping platypus SOX genes; autosomal location of SOX9 excludes it from sex determining role. Cytogenetic and Genome Research, 116, 3, 232-234. 10.1159/000098192
2007 Rens, W., O'Brien, P., Grutzner, F., Clarke, O., Graphodatskaya, D., Tsend-Ayush, E. ... Ferguson-Smith, M. (2007). The multiple sex chromosomes of platypus and echidna are not completely identical and several share homology with the avian Z. Genome Biology (Online Edition), 8, 11, R243:1-R243:21. 10.1186/gb-2007-8-11-r243
2007 McMillan, D., Miethke, P., Alsop, A., Rens, W., O'Brien, P., Trifonov, V. ... Graves, J. (2007). Characterizing the chromosomes of the platypus (Ornithorhynchus anatinus). Chromosome Research, 15, 8, 961-974. 10.1007/s10577-007-1186-2
2007 El-Mogharbel, N., Wakefield, M., Deakin, J., Tsend-Ayush, E., Grutzner, F., Alsop, A. ... Graves, J. (2007). DMRT gene cluster analysis in the platypus: New insights into genomic organization and regulatory regions. Genomics, 89, 1, 10-21. 10.1016/j.ygeno.2006.07.017
2007 Wallis, M., Waters, P., Delbridge, M., Kirby, P., Pask, A., Grutzner, F. ... Graves, J. (2007). Sex determination in platypus and echidna: autosomal location of SOX3 confirms the absence of SRY from monotremes. Chromosome Research, 15, 8, 949-959. 10.1007/s10577-007-1185-3
2006 Yue, Y., Tsend-Ayush, E., Grutzner, F., Grossmann, B. & Haaf, T. (2006). Segmental duplication associated with evolutionary instability of human chromosome 3p25. Cytogenetic and Genome Research, 112, 3-4, 202-207. 10.1159/000089871
2006 Sankovic, N., Delbridge, M., Grutzner, F., Ferguson-Smith, M., O'Brien, P. & Graves, J. (2006). Construction of a highly enriched marsupial Y chromosome-specific BAC sub-library using isolated Y chromosomes. Chromosome Research, 14, 6, 657-664. 10.1007/s10577-006-1076-z
2006 Grutzner, F., Ashley, T., Rowell, D. & Graves, J. (2006). How did the platypus get its sex chromosome chain? A comparison of meiotic multiples and sex chromosomes in plants and animals. Chromosoma, 115, 2, 75-88. 10.1007/s00412-005-0034-4
2006 Ezaz, T., Valenzuela, N., Grutzner, F., Miura, I., Georges, A., Burke, R. & Graves, J. (2006). An XX/XY sex microchromosome system in a freshwater turtle, Chelodina longicollis (Testudines: Chelidae) with genetic sex determination. Chromosome Research, 14, 2, 139-150. 10.1007/s10577-006-1029-6
2006 Delbridge, M., Wallis, M., Kirby, P., Alsop, A., Grutzner, F. & Graves, J. (2006). Assignment of SOX1 to platypus chromosome 20q by fluorescence in situ hybridization. Cytogenetic and Genome Research, 112, 3-4, 342L-1-342L-2. 10.1159/000089902
2005 Yue, Y., Grossmann, B., Tsend-Ayush, E., Grutzner, F., Ferguson-Smith, M., Yang, F. & Haaf, T. (2005). Genomic structure and paralogous regions of the inversion breakpoint occurring between human chromosome 3p12.3 and orangutan chromosome 2. Cytogenetic and Genome Research, 108, 1-3, 98-105. 10.1159/000080807
2005 Tsend-Ayush, E., O'Sullivan, L., Grutzner, F., Onnebo, S., Lewis, R., Dellbridge, M. ... Ward, A. (2005). RBMX gene is essential for brain development in zebrafish. Developmental Dynamics, 234, 3, 682-688. 10.1002/dvdy.20432
2004 Grutzner, F. & Graves, J. (2004). A platypus’ eye view of the mammalian genome. Current Opinion in Genetics & Development, 14, 6, 642-649. 10.1016/j.gde.2004.09.006
2004 Rens, W., Grutzner, F., O'Brien, P., Fairclough, H., Graves, J. & Ferguson-Smith, M. (2004). Resolution and evolution of the duck-billed platypus karyotype with an X1Y1X2Y2X3Y3X4Y4X5Y5 male sex chromosome constitution. Proceedings of the National Academy of Sciences of the United States of America, 101, 46, 16257-16261. 10.1073/pnas.0405702101
2004 Tsend-Ayush, E., Grutzner, F., Grossmann, B., Hansel, U., Sudbrak, R. & Haaf, T. (2004). Plasticity of human chromosome 3 during primate evolution. Genomics, 83, 2, 193-202. 10.1016/j.ygeno.2003.08.012
2004 Grutzner, F., Rens, W., Tsend-Ayush, E., El-Mogharbel, N., O'Brien, P., Jones, R. ... Graves, J. (2004). In the platypus a meiotic chain of ten sex chromosomes shares genes with the bird Z and mammal X chromosomes. Nature, 432, 7019, 913-917. 10.1038/nature03021
2003 Chapman, M., Charchar, F., Kinston, S., Bird, C., Grafham, D., Rogers, J. ... Gottgens, B. (2003). Comparative and functional analyses of LYL1 loci establish marsupial sequences as a model for phylogenetic footprinting. Genomics, 81, 3, 249-259. 10.1016/S0888-7543(03)00005-3
2003 Grutzner, F., Deakin, J., Rens, W., El-Mogharbel, N. & Marshall Graves, J. (2003). The monotreme genome: a patchwork of reptile mammal and unique features?. Comparative Biochemistry and Physiology A-Molecular and Integrative Physiology, 136, 4, 867-881. 10.1016/j.cbpb.2003.09.014
2003 Santucciu, C., Grutzner, F., Carvalho-Silva, D. & Graves, J. (2003). Isolation of chromosomal regions controlling intersex development in a marsupial. Cytogenetic and Genome Research, 101, 3-4, 224-228. 10.1159/000074341
2002 Grutzner, F., Crollius, H., Lutjens, G., Weissenbach, J., Ropers, H. & Haaf, T. (2002). Four-Hundred Million Years of Conserved Synteny of Human Xp and Xq Genes on Three Tetraodon Chromosomes. Genome Research, 12, 9, 1316-1322. 10.1101/gr.222402
2002 Smith, S., Snell, P., Grutzner, F., Bench, A., Haaf, T., Metcalfe, J. ... Elgar, G. (2002). Analyses of the extent of shared synteny and conserved gene orders between the genome of fugu rubripes and human 20q. Genome Research, 12, 5, 776-784. 10.1101/gr.221802
2001 Toder, R., Grutzner, F., Haaf, T. & Bausch, E. (2001). Species-specific evolution of repeated DNA sequences in great apes. Chromosome Research, 9, 6, 431-435. 10.1023/A:1011605824530
2001 Zimdahl, H., Gosele, C., Lutjens, G., Grutzner, F., Kreitler, T., Voss, K. ... Knoblauch, M. (2001). Assignment of the huntingtin (Hdh) gene, the huntingtin associated protein (Hap1) gene, and the huntingtin interacting protein (Hip1) gene to rat chromosomes 14, 10, and 12 by radiation hybrid mapping and fluorescent in situ hybridization. Cytogenetic and Genome Research, 94, 1-2, 101-104. 10.1159/000048797
2001 Grutzner, F., Tsend-Ayush, E., Stout, K., Munsche, S., Niveleau, A., Nanda, I. ... Haaf, T. (2001). Chicken microchromosomes are hypermethylated and can be identified by specific painting probes. Cytogenetic and Genome Research, 93, 3-4, 265-269. 10.1159/000056996
2001 Bouchireb, N., Grutzner, F., Haaf, T., Stephens, R., Elgar, G., Green, A. & Clark, M. (2001). Comparative mapping of the human 9q34 region in Fugu rubripes. Cytogenetic and Genome Research, 94, 3-4, 173-179. 10.1159/000048811
2001 Zend-Ajusch, E., Gruetzner, F., Haensel, U., Sudbrack, R., Ropers, H. & Haaf, T. (2001). A large intragenomic duplication homologous to human chromosome 3p21-24 during hominoid evolution.. AMERICAN JOURNAL OF HUMAN GENETICS, 69, 4, 329-329.
2000 Brunner, B., Grutzner, F., Yaspo, M., Ropers, H., Haaf, T. & Kalscheuer, V. (2000). Molecular cloning and characterization of the Fugu rubripes MEST/COPG2 imprinting cluster and chromosomal localization in Fugu and Tetraodon nigroviridis. Chromosome Research, 8, 6, 465-476. 10.1023/A:1009263504671
2000 Nanda, I., Zend-Ajusch, E., Shan, Z., Grützner, F., Schartl, M., Burt, D. ... Schmid, M. (2000). Conserved synteny between the chicken Z sex chromosome and human chromosome 9 includes the male regulatory gene DMRT1: A comparative (re)view on avian sex determination. Cytogenetics and Cell Genetics, 89, 1-2, 67-78. 10.1159/000015567
2000 Gösele, C., Grützner, F., Pesquero, J., Silva, J., Junge, T., Ganten, D. ... Knoblauch, M. (2000). Assignment of the kinin receptor B1 and B2 genes (Bdkrb1 and Bdkrb2) to rat chromosome 6q3.2 by FISH and radiation hybrid mapping. Cytogenetics and Cell Genetics, 89, 1-2, 51-52. 10.1159/000015561
2000 Haaf, T., Crollius, H., Weissenbach, J., Lutjens, G., Brunner, B., Ropers, H. & Grutzner, F. (2000). Comparative gene and genome mapping in pufferfish and humans.. AMERICAN JOURNAL OF HUMAN GENETICS, 67, 4, 23-23.
2000 Cai, L., Lindpaintner, K., Browne, J., Gruetzner, F., Haaf, T., James, M. & Bihoreau, M. (2000). An anchored YAC-STS framework for the rat genome. Cytogenetics and Cell Genetics, 89, 3-4, 168-170. 10.1159/000015606
1999 Gruetzner, F., Roest-Crollius, H., Lutjens, G., Barnes, D., Ropers, H., Weissenbach, J. & Haaf, T. (1999). Comparative gene and genome mapping in Tetraodon nigroviridis and Fugu rubripes. CYTOGENETICS AND CELL GENETICS, 85, 1-2, 32-32.
1999 Sharon, D., Glusman, G., Pilpel, Y., Khen, M., Gruetzner, F., Haaf, T. & Lancet, D. (1999). Primate evolution of an olfactory receptor cluster: Diversification by gene conversion and recent emergence of pseudogenes. Genomics, 61, 1, 24-36. 10.1006/geno.1999.5900
1999 Nanda, I., Shan, Z., Schartl, M., Burt, D., Koehler, M., Nothwang H-, G. ... Schmid, M. (1999). 300 million years of conserved synteny between chicken Z and human chromosome 9 [2]. Nature Genetics, 21, 3, 258-259. 10.1038/6769
1999 Roemer, I., Grutzner, F., Winking, H., Haaf, T., Orth, A., Skidmore, L. ... Fundele, R. (1999). Genome evolution - Global methylation in eutherian hybrids. NATURE, 401, 6749, 131-132. 10.1038/43604
1999 Shan, Z., Zend-Ajusch, E., Gruetzner, F. & Haaf, T. (1999). Cytogenetic and molecular characterization of evolutionary chromosome breakpoints in great apes.. AMERICAN JOURNAL OF HUMAN GENETICS, 65, 4, A357-A357.
1999 Grützner, F., Himmelbauer, H., Paulsen, M., Hans-Ropers, H. & Haaf, T. (1999). Comparative mapping of mouse and rat chromosomes by fluorescence in situ hybridization. Genomics, 55, 3, 306-313. 10.1006/geno.1998.5658
1999 Roemer, I., Grützner, F., Winking, H., Haaf, T., Orth, A., Skidmore, L. ... Fundele, R. (1999). Global methylation in eutherian hybrids. Nature, 401, 6749, 131-132.
1999 Grützner, F., Lütjens, G., Rovira, C., Barnes, D., Ropers, H. & Haaf, T. (1999). Classical and molecular cytogenetics of the pufferfish Tetraodon nigroviridis. Chromosome Research, 7, 8, 655-662. 10.1023/A:1009292220760
1998 Gläser, B., Grützner, F., Willmann, U., Stanyon, R., Arnold, N., Taylor, K. ... Schempp, W. (1998). Simian Y Chromosomes: Species-specific rearrangements of DAZ, RBM, and TSPY versus contiguity of PAR and SRY. Mammalian Genome, 9, 3, 226-231. 10.1007/s003359900730
1997 Gläser, B., Grützner, F., Taylor, K., Schiebel, K., Meroni, G., Tsioupra, K. ... Schempp, W. (1997). Comparative mapping of Xp22 genes in hominoids - evolutionary linear instability of their Y homologues. Chromosome Research, 5, 3, 167-176. 10.1023/A:1018490713273
1993 Schempp, W., Toder, R., Rietschel, W., Grützner, F., Mayerová, A. & Gauckler, A. (1993). Inverted and satellited Y chromosome in the orangutan (Pongo pygmaeus). Chromosome Research, 1, 1, 69-75. 10.1007/BF00710609
Lynch, V. J., Nnamani, M., Brayer, K. J., Emera, D., Wertheim, J. O., Pond, S. L. K. ... Wagner, G. P. (). Lineage-specific transposons drove massive gene expression recruitments
during the evolution of pregnancy in mammals. -.

Book Chapters

Year Citation
2011 Rowell, D., Lim, S. & Grutzner, F. (2011). Chromosome Analysis in Invertebrates and Vertebrates. In V. Orgogozo & M. Rockman (Eds.), Methods in Molecular Biology - Volume 772 - Molecular Methods for Evolutionary Genetics (pp. 13-36). United States: Springer. 10.1007/978-1-61779-228-1_2
2006 Grutzner, F., Rens, W., Watson, J., Ferguson-Smith, M. & Graves, J. (2006). The chromosomes of monotreme mammals. In Mammalian chromosome atlas (pp. 1-8). Hoboken, New Jersey, USA: Wiley.

Conference Papers

Year Citation
2008 Grutzner, F. (2008). Evolution and organization of monotreme sex chromosomes. World Congress on Reproductive Biology. Kailua Kona, HI. 10.1093/biolreprod/78.s1.282c
2007 Rens, W., O'Brien, P. C., Grutzner, F., Clarke, O., Graphodatskaya, D., Tsend-Ayush, E. ... Ferguson-Smith, M. (2007). Characterization of the platypus and echidna sex chromosome system. 16th International Chromosome Conference (ICC 16). Amsterdam, NETHERLANDS.
2007 Veyrunes, F., Rens, W., Waters, P., Miethke, P., Alsop, A., Grutzner, F. ... Graves, J. (2007). Does the platypus sex chromosome system derive from an ancestral bird ZW system?. 16th International Chromosome Conference (ICC 16). Amsterdam, NETHERLANDS.
2006 Grutzner, F. (2006). Sex Chromosomes Down Under: XY in platypus. European Workshop on Molecular and Cellular Endocrinology of the Testis. Bad Aibling, Germany.
2005 Grutzner, F., Rens, W., Tsend-Ayush, E., El-Mogharbel, N., O'Brien, P., Jones, R. ... Graves, J. (2005). Evolution and organization of the ten sex chromosome system in platypus. ComBio. Adelaide, South Australia.
2004 Grutzner, F., Rens, W., Jones, R., Tsend-Ayush, E. & Graves, J. (2004). Platypus have four male-specific chromosomes that segregate together at meiosis. HGM. Berlin, Germany.

Conference Items

Year Citation
2004 Yue, Y., Grossmann, B., Tsend-Ayush, E., Grutzner, F., Ferguson-Smith, M., Yang, F. & Haaf, T. (2004). Plasticity of human chromosome 3 during primate evolution. Human Genome Meeting HGM2004. Berlin, Germany.

Resarch funding acknowledgements

Australian research council, Australian Geographic

I teach a substantial component of the thir year genetics course "Genes, Genomes and Molecular Evolution"

Current Staff:

Dr Tasman Daish (Lecturer)

Dr Dan Kortschak (visiting research associate)

Tahlia Perry (PhD candidate)

David Stevens (PhD candidate)

Reuben Jacob (PhD candidate)

Nicole Williams (Masters candidate)

Ellen Gillett (honours 2016)

Eunice Lee (honours 2016)

Hendrik Bethke (visiting student)

 

 

Memberships

Date Role Membership Country
2015 - ongoing Member ARC College of Experts Australia

Editorial Boards

Date Role Editorial Board Name Country
2013 - ongoing Associate Editor BMC Genomics

Offices Held

Date Office Name Institution Country
2006 - 2016 ARC research fellow and group leader The University of Adelaide Australia
2006 - 2006 Lecturer in Genetics The University of Adelaide Australia
2003 - 2005 ARC research fellow Australian National University Australia
2001 - 2002 Postdoctoral researcher Australian National University
2001 - 2001 Postdoctoral researcher Max Planck Insitute of Molecular Genetics Germany
Position
Genetics Lecturer
Phone
83134812
Fax
8313 4362
Campus
North Terrace
Building
Molecular Life Sciences
Room Number
2 11
Org Unit
Genetics & Evolution

top