Eryk Andreas
School of Biological Sciences
Faculty of Sciences, Engineering and Technology
Research focus and research interest
My long-standing goals are to understand epigenetics regulation mechanism in oocyte and preimplantation embryo development and how epigenetics changes during early embryo development could affect offspring post-natal life. I focus on the effect of metabolic stress in female such as ageing and obesity, on oocytes, embryos and offspring long-term health. Ageing and obesity in female oftentimes share similar spectrum of phenotypic, especially mitochondria i.e. low mitochondrial number, abnormal mitochondrial morphology and impaired mitochondrial function. Since mitochondria are maternally inherited, defective mitochondria in the oocyte could be inherited to the next generation and possess potential risk to the offspring long-term health. Better understanding of how abnormal mitochondria are formed, provide potential information to prevent mitochondrial defect and its inheritance to the next generation.
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Language Competencies
Language Competency English Can read, write, speak, understand spoken and peer review Indonesian Can read, write, speak, understand spoken and peer review -
Education
Date Institution name Country Title 2013 - 2016 University of Bonn Germany PhD 2008 - 2010 Bogor Agricultural University Indonesia MSc 2004 - 2008 Bogor Agricultural University Indonesia BSc -
Postgraduate Training
Date Title Institution Country 2019 NHMRC Grant-funded Researcher University of Adelaide Australia 2016 - 2018 Postdoctoral Research Associate Washington University in St. Louis School of Medicine United States -
Research Interests
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Journals
Year Citation 2024 Chadchan, S. B., Popli, P., Liao, Z., Andreas, E., Dias, M., Wang, T., . . . Kommagani, R. (2024). A GREB1-steroid receptor feedforward mechanism governs differential GREB1 action in endometrial function and endometriosis. Nature Communications, 15(1), 17 pages.
Scopus4 Europe PMC22024 Gonzalez, M. B., Campugan, C. A., Connaughton, H. S., Andreas, E., Winstanley, Y. E., Williams, E. J., . . . Robker, R. L. (2024). BGP-15 mitigates adverse impacts of aging on sperm quality, fertility, and offspring health in male mice. Reproduction, 168(3), e240105 -1-e240105-13.
Scopus12024 Winstanley, Y. E., Gonzalez, M. B., Andreas, E., Connaughton, H., Bergen, J., Ween, M., . . . Robker, R. L. (2024). Drinking water quality impacts oocyte viability and embryo development. Frontiers in Reproductive Health, 6, 1-14.
2024 Penn, A., Andreas, E., Okada, T., & St John, J. C. (2024). Nuclear transfer leads to aberrant cell cycle regulation and translation, as determined by gene expression, and selection of mitochondrial DNA in porcine blastocysts. NAR Molecular Medicine, 1(4).
2024 Andreas, E., Penn, A., Okada, T., & St. John, J. C. (2024). Supplementation of Oocytes by Microinjection with Extra Copies of mtDNA Alters Metabolite Profiles and Interactions with Expressed Genes in a Tissue-Specific Manner. Biomolecules, 14(11), 1477-1-1477-20.
2023 McIlfatrick, S., O'Leary, S., Okada, T., Penn, A., Nguyen, V. H. T., McKenny, L., . . . St. John, J. C. (2023). Does supplementation of oocytes with additional mtDNA influence developmental outcome?. iScience, 26(2), 105956-1-105956-27.
Scopus2 WoS1 Europe PMC22022 Umehara, T., Winstanley, Y. E., Andreas, E., Morimoto, A., Williams, E. J., Smith, K. M., . . . Robker, R. L. (2022). Female reproductive life span is extended by targeted removal of fibrotic collagen from the mouse ovary.. Science Advances, 8(24), eabn4564-1-eabn4564-17.
Scopus79 WoS25 Europe PMC642022 St John, J. C., Okada, T., Andreas, E., & Penn, A. (2022). The role of mtDNA in oocyte quality and embryo development. Molecular Reproduction and Development, 90(7), 621-633.
Scopus11 WoS4 Europe PMC82021 Andreas, E., Winstanley, Y. E., & Robker, R. L. (2021). Effect of obesity on the ovarian follicular environment and developmental competence of the oocyte. Current Opinion in Endocrine and Metabolic Research, 18, 152-158.
Scopus72021 Andreas, E., Pandey, H. O., Hoelker, M., Salilew-Wondim, D., Gebrmedhn, S., Schellander, K., & Tesfaye, D. (2021). The regulatory role of miR-20a in bovine cumulus cells and its contribution to oocyte maturation. Zygote: the biology of gametes and early embryos, 29(6), 435-444.
Scopus5 WoS1 Europe PMC32019 Andreas, E., Reid, M., Zhang, W., & Moley, K. H. (2019). The effect of maternal high-fat/high-sugar diet on offspring oocytes and early embryo development. Molecular human reproduction, 25(11), 717-728.
Scopus39 Europe PMC252017 Andreas, E., Salilew-Wondim, D., Rings, F., Held, E., Hoelker, M., Neuhoff, C., . . . Tesfaye, D. (2017). 176 REGULATORY ROLE OF miR-20a DURING BOVINE OOCYTE MATURATION. Reproduction, Fertility and Development, 29(1), 196.
2016 Andreas, E., Hoelker, M., Neuhoff, C., Tholen, E., Schellander, K., Tesfaye, D., & Salilew-Wondim, D. (2016). MicroRNA 17–92 cluster regulates proliferation and differentiation of bovine granulosa cells by targeting PTEN and BMPR2 genes. Cell and Tissue Research, 366(1), 219-230.
Scopus52 Europe PMC272015 Arief, I. I., Budiman, C., Jenie, B. S. L., Andreas, E., & Yuneni, A. (2015). Plantaricin IIA-1A5 from Lactobacillus plantarum IIA-1A5 displays bactericidal activity against Staphylococcus aureus. Beneficial Microbes, 6(4), 603-613.
Scopus32 Europe PMC92014 Andreas, E., Arifiantini, I., Saputra, F., Ishak, A. B. L., Imron, M., & Sumantri, C. (2014). Effect of FSH β-sub unit and FSHR genes polymorphisms on superovulatory response traits. Journal of the Indonesian Tropical Animal Agriculture, 39(4), 197-203.
Scopus52013 Arief, I. I., Jakaria., Suryati, T., Wulandari, Z., & Andreas, E. (2013). Isolation and characterization of plantaricin produced by Lactobacillus plantarum strains (IIA-1A5, IIA-1B1, IIA-2B2). Media Peternakan, 36(2), 91-100.
Scopus252012 Misrianti, R., Anggraeni, A., Andreas, E., & Sumantri, C. (2012). Growth hormone gene polymorphism and its association with partial cumulative milk yields of holstein friesian dairy cattle. Media Peternakan, 35(3), 145-151.
Scopus72012 Nuraini, H., Primasari, A., Andreas, E., & Sumantri, C. (2012). The use of cytochrome b gene as a specific marker of the rat meat (Rattus norvegicus) on meat and meat products. Media Peternakan, 35(1), 15-20.
Scopus102011 Sumantri, C., Jakaria, J., Yamin, M., Nuraini, H., & Andreas, E. (2011). Identification of myostatin gene c.960delG locus polymorphism in Indonesian local sheep by using PCR-SSCP method. Journal of the Indonesian Tropical Animal Agriculture, 36(3), 145-151.
Scopus22010 Andreas, E., Sumantri, C., Nuraini, H., Farajallah, A., & Anggraeni, A. (2010). Identification of gh. Journal of the Indonesian Tropical Animal Agriculture, 35(4), 215-221.
Scopus222010 Anggraeni, A., Sumantri, C., Farajallah, A., & Andreas, E. (2010). Kappa-casein genotypic frequencies in holstein-friesian dairy cattle in west java province. Media Peternakan, 33(2), 61-67.
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Conference Papers
Year Citation 2016 Andreas, E., Salilew-Wondim, D., Rings, F., Held, E., Hoelker, M., Neuhoff, C., . . . Tesfaye, D. (2016). The role of miR-20a during bovine oocyte maturation. In fghfdg. Hannover, Germany. 2015 Andreas, E., Salilew-Wondim, D., Hoelker, M., Neuhoff, C., Tholen, E., Looft, C., . . . Tesfaye, D. (2015). The role of microRNA 17-92 cluster on bovine granulosa cell differentiation and proliferation. In Vortragstagung der DGfZ und GfT. Berlin, Germany. -
Conference Items
Year Citation 2016 Andreas, E., Salilew-Wondim, D., Hoelker, M., Neuhoff, C., Tholen, E., Looft, C., . . . Tesfaye, D. (2016). 142 microRNA-17-92 CLUSTER REGULATES BOVINE GRANULOSA CELL FUNCTION BY TARGETING BMPR2 AND PTEN GENES. Poster session presented at the meeting of Reproduction, Fertility and Development. Louisville, Kentucky USA: CSIRO Publishing.
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