Eryk Andreas

Eryk Andreas

School of Biomedicine

Faculty of Health and Medical Sciences

Research focus and research interest

My long-standing goals are to understand epigenetics regulation mechanism in oocyte and preimplantation embryo development and how epigenetics changes during early embryo development could affect offspring post-natal life. I focus on the effect of metabolic stress in female such as ageing and obesity, on oocytes, embryos and offspring long-term health. Ageing and obesity in female oftentimes share similar spectrum of phenotypic, especially mitochondria i.e. low mitochondrial number, abnormal mitochondrial morphology and impaired mitochondrial function. Since mitochondria are maternally inherited, defective mitochondria in the oocyte could be inherited to the next generation and possess potential risk to the offspring long-term health. Better understanding of how abnormal mitochondria are formed, provide potential information to prevent mitochondrial defect and its inheritance to the next generation.

  • Journals
    Year Citation
    2023 McIlfatrick, S., O'Leary, S., Okada, T., Penn, A., Nguyen, V. H. T., McKenny, L., . . . St. John, J. C. (2023). Does supplementation of oocytes with additional mtDNA influence developmental outcome?. iScience, 26(2), 105956-1-105956-27.
    DOI Scopus1 WoS1 Europe PMC1
    2022 Umehara, T., Winstanley, Y. E., Andreas, E., Morimoto, A., Williams, E. J., Smith, K. M., . . . Robker, R. L. (2022). Female reproductive life span is extended by targeted removal of fibrotic collagen from the mouse ovary.. Science Advances, 8(24), eabn4564-1-eabn4564-17.
    DOI Scopus18 WoS17 Europe PMC12
    2022 St John, J. C., Okada, T., Andreas, E., & Penn, A. (2022). The role of mtDNA in oocyte quality and embryo development. Molecular Reproduction and Development, 90(7), 621-633.
    DOI Scopus4 WoS3 Europe PMC3
    2021 Andreas, E., Winstanley, Y. E., & Robker, R. L. (2021). Effect of obesity on the ovarian follicular environment and developmental competence of the oocyte. Current Opinion in Endocrine and Metabolic Research, 18, 152-158.
    DOI Scopus3
    2021 Andreas, E., Pandey, H. O., Hoelker, M., Salilew-Wondim, D., Gebrmedhn, S., Schellander, K., & Tesfaye, D. (2021). The regulatory role of miR-20a in bovine cumulus cells and its contribution to oocyte maturation. Zygote: the biology of gametes and early embryos, 29(6), 435-444.
    DOI Scopus1 WoS1 Europe PMC1
    2019 Andreas, E., Reid, M., Zhang, W., & Moley, K. H. (2019). The effect of maternal high-fat/high-sugar diet on offspring oocytes and early embryo development. Molecular human reproduction, 25(11), 717-728.
    DOI Scopus30 Europe PMC17
    2017 Andreas, E., Salilew-Wondim, D., Rings, F., Held, E., Hoelker, M., Neuhoff, C., . . . Tesfaye, D. (2017). 176 REGULATORY ROLE OF miR-20a DURING BOVINE OOCYTE MATURATION. Reproduction, Fertility and Development, 29(1), 196.
    DOI
    2016 Andreas, E., Hoelker, M., Neuhoff, C., Tholen, E., Schellander, K., Tesfaye, D., & Salilew-Wondim, D. (2016). MicroRNA 17–92 cluster regulates proliferation and differentiation of bovine granulosa cells by targeting PTEN and BMPR2 genes. Cell and Tissue Research, 366(1), 219-230.
    DOI Scopus46 Europe PMC21
    2015 Arief, I. I., Budiman, C., Jenie, B. S. L., Andreas, E., & Yuneni, A. (2015). Plantaricin IIA-1A5 from Lactobacillus plantarum IIA-1A5 displays bactericidal activity against Staphylococcus aureus. Beneficial Microbes, 6(4), 603-613.
    DOI Scopus28 Europe PMC6
    2014 Andreas, E., Arifiantini, I., Saputra, F., Ishak, A. B. L., Imron, M., & Sumantri, C. (2014). Effect of FSH β-sub unit and FSHR genes polymorphisms on superovulatory response traits. Journal of the Indonesian Tropical Animal Agriculture, 39(4), 197-203.
    DOI Scopus4
    2013 Arief, I. I., Jakaria., Suryati, T., Wulandari, Z., & Andreas, E. (2013). Isolation and characterization of plantaricin produced by Lactobacillus plantarum strains (IIA-1A5, IIA-1B1, IIA-2B2). Media Peternakan, 36(2), 91-100.
    DOI Scopus20
    2012 Misrianti, R., Anggraeni, A., Andreas, E., & Sumantri, C. (2012). Growth hormone gene polymorphism and its association with partial cumulative milk yields of holstein friesian dairy cattle. Media Peternakan, 35(3), 145-151.
    DOI Scopus5
    2012 Nuraini, H., Primasari, A., Andreas, E., & Sumantri, C. (2012). The use of cytochrome b gene as a specific marker of the rat meat (Rattus norvegicus) on meat and meat products. Media Peternakan, 35(1), 15-20.
    DOI Scopus10
    2011 Sumantri, C., Jakaria, J., Yamin, M., Nuraini, H., & Andreas, E. (2011). Identification of myostatin gene c.960delG locus polymorphism in Indonesian local sheep by using PCR-SSCP method. Journal of the Indonesian Tropical Animal Agriculture, 36(3), 145-151.
    DOI Scopus2
    2010 Andreas, E., Sumantri, C., Nuraini, H., Farajallah, A., & Anggraeni, A. (2010). Identification of gh. Journal of the Indonesian Tropical Animal Agriculture, 35(4), 215-221.
    DOI Scopus21
    2010 Anggraeni, A., Sumantri, C., Farajallah, A., & Andreas, E. (2010). Kappa-casein genotypic frequencies in holstein-friesian dairy cattle in west java province. Media Peternakan, 33(2), 61-67.
    DOI Scopus6

  • Conference Papers
    Year Citation
    2016 Andreas, E., Salilew-Wondim, D., Rings, F., Held, E., Hoelker, M., Neuhoff, C., . . . Tesfaye, D. (2016). The role of miR-20a during bovine oocyte maturation. In fghfdg. Hannover, Germany.
    2015 Andreas, E., Salilew-Wondim, D., Hoelker, M., Neuhoff, C., Tholen, E., Looft, C., . . . Tesfaye, D. (2015). The role of microRNA 17-92 cluster on bovine granulosa cell differentiation and proliferation. In Vortragstagung der DGfZ und GfT. Berlin, Germany.

  • Conference Items
    Year Citation
    2016 Andreas, E., Salilew-Wondim, D., Hoelker, M., Neuhoff, C., Tholen, E., Looft, C., . . . Tesfaye, D. (2016). 142 microRNA-17-92 CLUSTER REGULATES BOVINE GRANULOSA CELL FUNCTION BY TARGETING BMPR2 AND PTEN GENES. Poster session presented at the meeting of Reproduction, Fertility and Development. Louisville, Kentucky USA: CSIRO Publishing.
    DOI
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