Eric Gowans
Adelaide Medical School
Faculty of Health and Medical Sciences
Professor Eric Gowans.
Professor Eric Gowans is an experienced molecular virologist who has worked on several of the hepatitis viruses throughout his career. His PhD studies examined the replication and pathogenesis of hepatitis B virus and later he worked on hepatitis delta virus. He has worked on hepatitis C virus (HCV) since the virus was discovered. More recently, he has worked on DNA and recombinant viral vectors as potential vaccines for human immunodeficiency virus (HIV) and HCV.
- My Research
- Career
- Publications
- Grants and Funding
- Teaching
- Supervision
- Professional Activities
- Contact
Professor Eric Gowans is an experienced molecular virologist who has worked on several of the hepatitis viruses throughout his career. His PhD studies examined the replication and pathogenesis of hepatitis B virus and later he worked on hepatitis delta virus. He has worked on hepatitis C virus (HCV) since the virus was discovered. More recently, he has worked on DNA and recombinant viral vectors as potential vaccines for human immunodeficiency virus (HIV) and HCV.
For more information please follow the link: http://www.basilhetzelinstitute.com.au/profile/eric-gowans/
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Appointments
Date Position Institution name 2010 - ongoing Senior Research Fellow University of Adelaide, Adelaide 2008 - 2009 Executive Director Women's & Children's Health Research Institute, North Adelaide -
Education
Date Institution name Country Title Napier College United Kingdom Fellow of Institute of Medical Laboratory Science University of South Australia, Adelaide Australia M. App. Sc. University of Adelaide, Adelaide Australia PhD -
Research Interests
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Journals
Year Citation 2023 Wijesundara, D. K., Yeow, A., McMillan, C. L. D., Choo, J. J. Y., Todorovic, A., Mekonnen, Z. A., . . . Muller, D. A. (2023). Superior efficacy of a skin-applied microprojection device for delivering a novel Zika DNA vaccine. Molecular Therapy Nucleic Acids, 34, 10 pages.
Scopus12022 Kovoor, J. G., Jacobsen, J. H. W., Duncan, J., Addo, A. A., Tivey, D. R., Babidge, W. J., . . . Maddern, G. J. (2022). Achieving safe surgery after COVID-19 vaccination.. ANZ J Surg, 92(5), 946-949.
Scopus3 WoS22022 Garcia-Valtanen, P., Hope, C. M., Masavuli, M. G., Yeow, A. E. L., Balachandran, H., Mekonnen, Z. A., . . . Grubor-Bauk., B. (2022). SARS-CoV-2 Omicron variant escapes neutralising antibodies and T cell responses more efficiently than other variants in mild COVID-19 convalescents.. Cell Reports Medicine, 3(6), 23 pages.
Scopus24 WoS15 Europe PMC212021 Garcia-Valtanen, P., Hope, C. M., Masavuli, M. G., Yeow, A. E. L., Balachandran, H., Mekonnen, Z. A., . . . Grubor-Bauk, B. (2021). COVID-19 convalescents exhibit deficient humoral and T cell responses to variant of concern Spike antigens at 12 month post-infection.
2020 Gummow, J., Masavuli, M., Mekonnen, Z. A., Li, Y., Wijesundara, D. K., Shrestha, A. C., . . . Grubor-Bauk, B. (2020). Safety profile of a multi-antigenic DNA vaccine against hepatitis C virus. Vaccines, 8(1), 1-15.
Scopus6 WoS4 Europe PMC42020 Mekonnen, Z. A., Masavuli, M. G., Yu, W., Gummow, J., Whelan, D. M., Al-Delfi, Z., . . . Grubor-Bauk, B. (2020). Enhanced T cell responses induced by a necrotic dendritic cell vaccine, expressing HCV NS3. Front Microbiol, 11, 1-13.
Scopus6 WoS3 Europe PMC32019 Grubor-Bauk, B., Wijesundara, D. K., Masavuli, M., Abbink, P., Peterson, R. L., Prow, N. A., . . . Gowans, E. J. (2019). NS1 DNA vaccination protects against Zika infection through T cell-mediated immunity in immunocompetent mice.. Sci Adv, 5(12), eaax2388.
Scopus50 WoS36 Europe PMC342019 Roy, S., Jaeson, M., Li, Z., Mahboob, S., Jackson, R., Grubor-Bauk, B., . . . Ranasinghe, C. (2019). Viral vector and route of administration determine the ILC and DC profiles responsible for downstream vaccine-specific immune outcomes. Vaccine, 37(10), 1266-1276.
Scopus15 WoS14 Europe PMC132019 Mekonnen, Z. A., Grubor-Bauk, B., Masavuli, M. G., Shrestha, A. C., Ranasinghe, C., Bull, R. A., . . . Wijesundara, D. K. (2019). Toward DNA-based T-cell mediated vaccines to target HIV-1 and hepatitis C virus: approaches to elicit localized immunity for protection. Frontiers in Cellular and Infection Microbiology, 9(APR), 1-8.
Scopus10 WoS7 Europe PMC42019 Shrestha, A. C., Wijesundara, D. K., Masavuli, M. G., Mekonnen, Z. A., Gowans, E. J., & Grubor-Bauk, B. (2019). Cytolytic perforin as an adjuvant to enhance the immunogenicity of DNA vaccines. Vaccines, 7(2), 14 pages.
Scopus11 WoS11 Europe PMC72019 Masavuli, M. G., Wijesundara, D. K., Underwood, A., Christiansen, D., Earnest-Silveira, L., Bull, R., . . . Grubor-Bauk, B. (2019). A hepatitis C virus DNA vaccine encoding a secreted, oligomerized form of envelope proteins is highly immunogenic and elicits neutralizing antibodies in vaccinated mice. Frontiers in immunology, 10(MAY), 1-19.
Scopus30 WoS24 Europe PMC212019 Christiansen, D., Earnest-Silveira, L., Grubor-Bauk, B., Wijesundara, D. K., Boo, I., Ramsland, P. A., . . . Torresi, J. (2019). Pre-clinical evaluation of a quadrivalent HCV VLP vaccine in pigs following microneedle delivery. Scientific Reports, 9(1), 1-13.
Scopus48 WoS33 Europe PMC302019 Mekonnen, Z. A., Grubor-Bauk, B., English, K., Leung, P., Masavuli, M. G., Shrestha, A. C., . . . Wijesundara, D. K. (2019). Single-dose vaccination with a hepatotropic adeno-associated virus efficiently localizes T cell immunity in the liver with the potential to confer rapid protection against Hepatitis C virus. Journal of Virology, 93(19), e00202-19-1-e00202-19-19.
Scopus9 WoS8 Europe PMC82018 Wijesundara, D., Gummow, J., Li, Y., Yu, W., Quah, B., Ranasinghe, C., . . . Grubor-Bauk, B. (2018). Induction of genotype-cross reactive, hepatitis C virus-specific cell mediated immunity in DNA-vaccinated mice. Journal of Virology, 92(8), 1-15.
Scopus20 WoS19 Europe PMC192018 Christiansen, D., Earnest-Silveira, L., Chua, B., Boo, I., Drummer, H. E., Grubor-Bauk, B., . . . Torresi, J. (2018). Antibody responses to a quadrivalent Hepatitis C viral-like particle vaccine adjuvanted with Toll-like receptor 2 agonists. Viral Immunology, 31(4), 1-6.
Scopus10 WoS8 Europe PMC62018 Christiansen, D., Earnest-Silveira, L., Chua, B., Meuleman, P., Boo, I., Grubor-Bauk, B., . . . Torresi, J. (2018). Immunological responses following administration of a genotype 1a/1b/2/3a quadrivalent HCV VLP vaccine. Scientific Reports, 8(1), 6483-1-6483-13.
Scopus36 WoS26 Europe PMC232017 Wijesundara, D., Yu, W., Quah, B., Eldi, P., Hayball, J., Diener, K., . . . Grubor-Bauk, B. (2017). Cytolytic DNA vaccine encoding lytic perforin augments the maturation of- and antigen presentation by- dendritic cells in a time-dependent manner. Scientific Reports, 7(1), 8530-1-8530-8.
Scopus7 WoS7 Europe PMC62017 Wijesundara, D., Ranasinghe, C., Grubor-Bauk, B., & Gowans, E. (2017). Emerging targets for developing T cell-mediated vaccines for human immunodeficiency virus (HIV)-1. Frontiers in Microbiology, 8(OCT), 2091-1-2091-7.
Scopus11 WoS9 Europe PMC82017 Masavuli, M., Wijesundara, D., Torresi, J., Gowans, E., & Grubor-Bauk, B. (2017). Preclinical development and production of virus-like particles as vaccine candidates for hepatitis C. Frontiers in Microbiology, 8(DEC), 11 pages.
Scopus29 WoS19 Europe PMC192016 Tomusange, K., Wijesundara, D., Gummow, J., Wesselingh, S., Suhrbier, A., Gowans, E., & Grubor-Bauk, B. (2016). Mucosal vaccination with a live recombinant rhinovirus followed by intradermal DNA administration elicits potent and protective HIV-specific immune responses. Scientific Reports, 6(1), 36658 -1-36658-11.
Scopus10 WoS10 Europe PMC82016 Kumar, A., Das, S., Mullick, R., Lahiri, P., Tatineni, R., Goswami, D., . . . Das, S. (2016). Immune responses against hepatitis C virus genotype 3a virus-like particles in mice: a novel VLP prime-adenovirus boost strategy. Vaccine, 34(8), 1115-1125.
Scopus21 WoS18 Europe PMC162016 Earnest-Silveira, L., Chua, B., Chin, R., Christiansen, D., Johnson, D., Herrmann, S., . . . Torresi, J. (2016). Characterization of a hepatitis C virus-like particle vaccine produced in a human hepatocyte-derived cell line. Journal of General Virology, 97(8), 1865-1876.
Scopus24 WoS20 Europe PMC172016 Tomusange, K., Wijesundara, D., Gummow, J., Garrod, T., Li, Y., Gray, L., . . . Gowans, E. (2016). A HIV-Tat/C4-binding protein chimera encoded by a DNA vaccine is highly immunogenic and contains acute EcoHIV infection in mice. Scientific Reports, 6(1), 29131-1-29131-10.
Scopus16 WoS16 Europe PMC142016 Earnest-Silveira, L., Christiansen, D., Herrmann, S., Ralph, S., Das, S., Gowans, E., & Torresi, J. (2016). Large scale production of a mammalian cell derived quadrivalent hepatitis C virus like particle vaccine. Journal of Virological Methods, 236, 87-92.
Scopus18 WoS16 Europe PMC112016 Jorritsma, S., Gowans, E., Grubor-Bauk, B., & Wijesundara, D. (2016). Delivery methods to increase cellular uptake and immunogenicity of DNA vaccines. Vaccine, 34(46), 5488-5494.
Scopus95 WoS79 Europe PMC602016 Grubor-Bauk, B., Yu, W., Wijesundara, D., Gummow, J., Garrod, T., Brennan, A., . . . Gowans, E. (2016). Intradermal delivery of DNA encoding HCV NS3 and perforin elicits robust cell-mediated immunity in mice and pigs. Gene Therapy, 23(1), 26-37.
Scopus24 WoS22 Europe PMC212015 Li, S., Plebanski, M., Smooker, P., & Gowans, E. J. (2015). Editorial: Why vaccines to HIV, HCV, and malaria have so far failed-challenges to developing vaccines against immunoregulating pathogens. Frontiers in Microbiology, 6(NOV), 3 pages.
Scopus12 WoS10 Europe PMC122015 Gummow, J., Li, Y., Yu, W., Garrod, T., Wijesundara, D., Brennan, A., . . . Gowans, E. (2015). A multiantigenic DNA vaccine that induces broad hepatitis C virus-specific T-Cell responses in mice. Journal of Virology, 89(15), 7991-8002.
Scopus21 WoS22 Europe PMC182015 Tomusange, K., Yu, W., Suhrbier, A., Wijesundara, D., Grubor-Bauk, B., & Gowans, E. (2015). Engineering human rhinovirus serotype-A1 as a vaccine vector. Virus Research, 203, 72-76.
Scopus7 WoS6 Europe PMC32014 Yu, W., Grubor-Bauk, B., Mullick, R., Das, S., & Gowans, E. J. (2014). Immunocompetent mouse models to evaluate intrahepatic T cell responses to HCV vaccines. HUMAN VACCINES & IMMUNOTHERAPEUTICS, 10(12), 3576-3578.
WoS22014 Gargett, T., Grubor-Bauk, B., Miller, D., Garrod, T., Yu, S., Wesselingh, S., . . . Gowans, E. (2014). Increase in DNA vaccine efficacy by virosome delivery and co-expression of a cytolytic protein. Clinical and Translational Immunology, 3(6), e18-1-e18-7.
Scopus20 WoS16 Europe PMC152014 Yu, W., Grubor-Bauk, B., Mullick, R., Das, S., & Gowans, E. J. (2014). Immunocompetent mouse models to evaluate intrahepatic T cell responses to HCV vaccines. Human vaccines & immunotherapeutics, 10(12), 3576-3578.
Scopus3 Europe PMC32014 Garrod, T., Grubor-Bauk, B., Yu, S., Gargett, T., & Gowans, E. (2014). Encoded novel forms of HSP70 or a cytolytic protein increase DNA vaccine potency.. Human vaccines & immunotherapeutics, 10(9). 2014 Garrod, T., Gargett, T., Yu, W., Major, L., Burrell, C., Wesselingh, S., . . . Gowans, E. (2014). Loss of long term protection with the inclusion of HIV pol to a DNA vaccine encoding gag. Virus Research, 192, 25-33.
Scopus6 WoS6 Europe PMC62014 Garrod, T., Grubor-Bauk, B., Gargett, T., Li, Y., Miller, D., Yu, W., . . . Gowans, E. (2014). DNA vaccines encoding membrane-bound or secreted forms of heat shock protein 70 exhibit improved potency. European Journal of Immunology, 44(7), 1992-2002.
Scopus22 WoS18 Europe PMC152014 Beard, M. R., Ffrench, R., Gowans, E. J., Helbig, K. J., Eyre, N. M., Douglas, M. M. W., . . . Drummer, H. E. (2014). A summary of the 20th International Symposium on Hepatitis C Virus and Related Viruses. Gastroenterology, 147(1), e1-e4.
Scopus1 WoS12014 Garrod, T., Grubor-Bauk, B., Yu, S., Gargett, T., & Gowans, E. (2014). Encoded novel forms of HSP70 or a cytolytic protein increase DNA vaccine potency. Human Vaccines and Immunotherapeutics, 10(9), 2679-2683.
Scopus9 WoS10 Europe PMC82014 Gargett, T., Grubor-Bauk, B., Garrod, T., Yu, W., Miller, D., Major, L., . . . Gowans, E. (2014). Induction of antigen-positive cell death by the expression of Perforin, but not DTa, from a DNA vaccine enhances the immune response. Immunology and Cell Biology, 92(4), 359-367.
Scopus22 WoS23 Europe PMC212014 Yu, W., Grubor-Bauk, B., Gargett, T., Garrod, T., & Gowans, E. (2014). A novel challenge model to evaluate the efficacy of hepatitis C virus vaccines in mice. Vaccine, 32(27), 3409-3416.
Scopus14 WoS13 Europe PMC102013 Gouklani, H., Beyer, C., Drummer, H., Gowans, E., Netter, H., & Haqshenas, G. (2013). Identification of specific regions in hepatitis C virus core, NS2 and NS5A that genetically interact with p7 and co-ordinate infectious virus production. Journal of Viral Hepatitis, 20(4), e66-e71.
Scopus13 WoS12 Europe PMC112013 Li, S., Lefranc, M., Miles, J., Alamyar, E., Giudicelli, V., Duroux, P., . . . Gowans, E. (2013). IMGT/HighV QUEST paradigm for T cell receptor IMGT clonotype diversity and next generation repertoire immunoprofiling. Nature Communications, 4(1), 1-13.
Scopus174 WoS147 Europe PMC1362012 Li, S., Roberts, S., Plebanski, M., Gouillou, M., Spelman, T., Latour, P., . . . Gowans, E. (2012). Induction of multi-functional T cells in a phase I clinical trial of dendritic cell immunotherapy in Hepatitis C virus infected individuals. PLoS One, 7(8), 1-7.
Scopus9 WoS8 Europe PMC72012 Wong, S., Haqshenas, G., Gowans, E., & MacKenzie, J. (2012). The dengue virus M protein localises to the endoplasmic reticulum and forms oligomers. FEBS Letters, 586(7), 1032-1037.
Scopus11 WoS11 Europe PMC72012 Gorzin, A., Ramsland, P., Tachedjian, G., & Gowans, E. (2012). Identification of residues involved in NS2 homodimerization and elucidation of their impact on the HCV life cycle. Journal of Viral Hepatitis, 19(3), 189-198.
Scopus7 WoS6 Europe PMC52012 Gouklani, H., Bull, R., Beyer, C., Coulibaly, F., Gowans, E., Drummer, H., . . . Haqshenas, G. (2012). Hepatitis C virus nonstructural protein 5B is involved in virus morphogenesis. Journal of Virology, 86(9), 5080-5088.
Scopus34 WoS37 Europe PMC282011 Wong, S. -S., Chebib, M., Haqshenas, G., Loveland, B., & Gowans, E. J. (2011). Dengue virus PrM/M proteins fail to show pH-dependent ion channel activity in Xenopus oocytes. Virology, 412(1), 83-90.
Scopus5 WoS7 Europe PMC52010 Gowans, E., Roberts, S., Jones, K., Dinatale, I., Latour, P., Chua, B., . . . Jackson, D. (2010). A phase I clinical trial of dendritic cell immunotherapy in HCV-infected individuals. Journal of Hepatology, 53(4), 599-607.
Scopus53 WoS46 Europe PMC372009 Meshkat, Z., Audsley, M., Beyer, C., Gowans, E., & Haqshenas, G. (2009). Reverse genetic analysis of a putative, influenze virus M2 HXXXW-like motif in the p7 protein of hepatitis C virus. Journal of Viral Hepatitis, 16(3), 187-194.
Scopus20 WoS20 Europe PMC192009 Martyn, J., Cardin, A., Wines, B., Cendron, A., Li, S., MacKenzie, J., . . . Gowans, E. (2009). Surface display of IgG Fc on baculovirus vectors enhances binding to antigen-presenting cells and cell lines expressing Fc receptors. Archives of Virology, 154(7), 1129-1138.
Scopus34 WoS29 Europe PMC232009 Li, S., Floess, S., Hamann, A., Gaudieri, S., Lucas, A., Hellard, M., . . . Gowans, E. (2009). Analysis of FOXP3+ regulatory T cells that display apparent viral antigen specificity during chronic hepatitis C virus infection. PLoS Pathogens, 5(12), 1000707-1-1000707-13.
Scopus30 WoS44 Europe PMC262008 Jones, K., Brown, L., Eriksson, E., Ffrench, R., Latour, P., Loveland, B., . . . Gowans, E. (2008). Human dendritic cells pulsed with specific lipopeptides stimulate autologous antigen-specific T cells without the addition of exogenous maturation factors. Journal of Viral Hepatitis, 15(10), 761-772.
Scopus13 WoS11 Europe PMC62008 Li, S., Gowans, E., Chougnet, C., Plebanski, M., & Dittmer, U. (2008). Natural Regulatory T Cells and Persistent Viral Infection. Journal of Virology, 82(1), 21-30.
Scopus128 WoS120 Europe PMC1082008 Chua, B., Eriksson, E., Brown, L., Zeng, W., Gowans, E., Torresi, J., & Jackson, D. (2008). A self-adjuvanting lipopeptide-based vaccine candidate for the treatment of hepatitis C virus infection. Vaccine, 26(37), 4866-4875.
Scopus51 WoS45 Europe PMC322008 Woollard, D., Haqshenas, G., Dong, X., Pratt, B., Kent, S., & Gowans, E. (2008). Virus-specific T-cell immunity correlates with control of gb virus b infection in marmosets. Journal of Virology, 82(6), 3054-3060.
Scopus27 WoS25 Europe PMC242007 Jones, K., Drane, D., & Gowans, E. (2007). Long-term storage of DNA-free RNA for use in vaccine studies. Biotechniques, 43(5), 675-681.
Scopus85 WoS69 Europe PMC562007 Chin, R., Earnest-Silveria, L., Koeberlain, B., Franz, S., Zentgraf, H., Dong, X., . . . Torresi, J. (2007). Modulation of MAPK pathways and cell cycle by replicating hepatitis B virus: Factors contributing to hepatocarcinogenesis. Journal of Hepatology, 47(3), 325-337.
Scopus61 WoS56 Europe PMC472007 Haqshenas, G., Dong, X., Netter, H., Torresi, J., & Gowans, E. (2007). A chimeric GB virus B encoding the hepatitis C virus hypervariable region 1 is infectious in vivo. Journal of General Virology, 88(3), 895-902.
Scopus26 WoS23 Europe PMC212007 Li, S., Jones, K., Woollard, D., Dromey, J., Paukovics, G., Plebanski, M., & Gowans, E. (2007). Defining target antigens for CD25⁺FOXP3⁺IFN-γ⁻ regulatory T cells in chronic hepatitis C virus infection. Immunology and Cell Biology, 85(3), 197-204.
Scopus56 WoS55 Europe PMC452007 Haqshenas, G., Mackenzie, J., Dong, X., & Gowans, E. (2007). Hepatitis C virus p7 protein is localized in the endoplasmic reticulum when it is encoded by a replication-competent genome. Journal of General Virology, 88(1), 134-142.
Scopus37 WoS35 Europe PMC292007 Haqshenas, G., Dong, X., Ewart, G., Bowden, S., & Gowans, E. (2007). A 2a/1b full-length p7 inter-genotypic chimeric genome of hepatitis C virus is infectious in vitro. Virology, 360(1), 17-26.
Scopus16 WoS17 Europe PMC152007 Martyn, J., Dong, X., Holmes-Brown, S., Pribul, P., Li, S., Drummer, H., & Gowans, E. (2007). Transient and stable expression of the HCV envelope glycoproteins in cell lines and primary hepatocytes transduced with a recombinant baculovirus. Archives of Virology, 152(2), 329-343.
Scopus15 WoS14 Europe PMC92006 Dong, X., Premkumar, A., Haqshenas, G., Gage, P., & Gowans, E. (2006). Amantadine inhibits the function of an ion channel encoded by GB virus-B but fails to inhibit virus replication. Journal of Clinical Virology, 36, S113.
2006 Premkumar, A., Dong, X., Haqshenas, G., Gage, P. W., & Gowans, E. J. (2006). Amantadine inhibits the function of an ion channel encoded by GB virus B, but fails to inhibit virus replication. Antiviral Therapy, 11(3), 289-295.
Scopus13 WoS11 Europe PMC112005 Jackson, D., Deliyannis, G., Eriksson, E., Dinatale, I., & Gowans, E. (2005). Dendritic Cell Immunotherapy of Hepatitis C Virus Infection: Toxicology of Lipopeptide-Loaded Dendritic Cells. International Journal of Peptide Research and Therapeutics, 11(4), 223-235.
Scopus8 WoS82005 Mijch, A., Sasadeusz, J., Hellard, M., Dunne, M., McCaw, R., Bowden, S., & Gowans, E. (2005). A study to investigate the impact of the initiation of highly active antiretroviral therapy on the hepatitis C virus viral load in HIV/HCV-coinfected patients. Antiviral Therapy, 10(2), 277-284.
Scopus3 WoS3 Europe PMC22004 Gowans, E. J., Jones, K. L., Bharadwaj, M., & Jackson, D. C. (2004). Prospects for dendritic cell vaccination in persistent infection with hepatitis C virus. Journal of Clinical Virology, 30(4), 283-290.
Scopus29 WoS27 Europe PMC192004 Li, D., Lott, W. B., Martyn, J., Haqshenas, G., & Gowans, E. J. (2004). Differential effects on the hepatitis C virus (HCV) internal ribosome entry site by vitamin B <inf>12</inf> and the HCV core protein. Journal of Virology, 78(21), 12075-12081.
Scopus15 WoS13 Europe PMC142004 Torresi, J., Bharadwaj, M., Jackson, D. C., & Gowans, E. J. (2004). Neutralising antibody, CTL and dendritic cell responses to hepatitis C virus: A preventive vaccine strategy. Current Drug Targets, 5(1), 41-56.
Scopus19 WoS20 Europe PMC142003 Ward, S. M., Tindle, R. W., Khromykh, A. A., & Gowans, E. J. (2003). Generation of CTL responses using Kunjin replicon RNA. Immunology and Cell Biology, 81(1), 73-78.
Scopus4 WoS4 Europe PMC32003 Fowler, N. L., Torresi, J., Jackson, D. C., Brown, L. E., & Gowans, E. J. (2003). Immune responses in hepatitis C virus infection: The role of dendritic cells. Immunology and Cell Biology, 81(1), 63-66.
Scopus10 WoS8 Europe PMC92003 Chuan, B. Y., Healy, A., Cameron, P. U., Stock, O., Rizkalla, M., Zeng, W., . . . Jackson, D. C. (2003). Maturation of dendritic cells with lipopeptides that represent vaccine candidates for hepatitis C virus. Immunology and Cell Biology, 81(1), 67-72.
Scopus33 WoS32 Europe PMC162003 Netter, H. J., Woo, W. P., Tindle, R., Macfarlan, R. I., & Gowans, E. J. (2003). Immunogenicity of recombinant HBsAg/HCV particles in mice pre-immunised with hepatitis B virus-specific vaccine. Vaccine, 21(21-22), 2692-2697.
Scopus28 WoS22 Europe PMC192003 Li, D., Takyar, S. T., Lott, W. B., & Gowans, E. J. (2003). Amino acids 1-20 of the hepatitis C virus (HCV) core protein specifically inhibit HCV IRES-dependent translation in HepG2 cells, and inhibit both HCV IRES- and cap-dependent translation in HuH7 and CV-1 cells. Journal of General Virology, 84(4), 815-825.
Scopus37 WoS34 Europe PMC282002 Greive, S. J., Webb, R. I., Mackenzie, J. M., & Gowans, E. J. (2002). Expression of the hepatitis C virus structural proteins in mammalian cells induces morphology similar to that in natural infection. Journal of Viral Hepatitis, 9(1), 9-17.
Scopus14 WoS12 Europe PMC42002 Takyar, S. S., Gowans, E. J., & Lott, W. B. (2002). Vitamin B12 stalls the 80 S ribosomal complex on the hepatitis C internal ribosome entry site. Journal of Molecular Biology, 319(1), 1-8.
Scopus18 WoS15 Europe PMC112001 Lott, W. B., Takyar, S. S., Tuppen, J., Crawford, D. H. G., Harrison, M., Sloots, T. P., & Gowans, E. J. (2001). Vitamin B12 and hepatitis C: Molecular biology and human pathology. Proceedings of the National Academy of Sciences of the United States of America, 98(9), 4916-4921.
Scopus35 WoS32 Europe PMC252001 Ward, S. M., Macnaughton, T. B., & Gowans, E. J. (2001). Development and characterisation of recombinant hepatitis delta virus-like particles. Virus Genes, 23(1), 97-104.
Scopus2 WoS2 Europe PMC12001 Netter, H. J., Macnaughton, T. B., Woo, W. P., Tindle, R., & Gowans, E. J. (2001). Antigenicity and immunogenicity of novel chimeric hepatitis B surface antigen particles with exposed hepatitis C virus epitopes. Journal of Virology, 75(5), 2130-2141.
Scopus82 WoS71 Europe PMC532000 Takyar, S. T., Li, D. S., Wang, Y. H., Trowbridge, R., & Gowans, E. J. (2000). Specific detection of minus-strand hepatitis C virus RNA by reverse- transcription polymerase chain reaction on polyA<sup>+</sup>-purified RNA. Hepatology, 32(2), 382-387.
Scopus33 WoS32 Europe PMC282000 Warrilow, D., Lott, W. B., Greive, S., & Gowans, E. J. (2000). Properties of the bovine viral diarrhoea virus replicase in extracts of infected MDBK cells. Archives of Virology, 145(10), 2163-2171.
Scopus8 WoS8 Europe PMC52000 Gowans, E. J. (2000). Distribution of markers of hepatitis C virus infection throughout the body. Seminars in Liver Disease, 20(1), 85-102.
Scopus90 WoS77 Europe PMC561999 Harvey, T. J., Macnaughton, T. B., Park, D. S., & Gowans, E. J. (1999). A cellular protein which binds hepatitis B virus but not hepatitis B surface antigen. Journal of General Virology, 80(3), 607-615.
Scopus7 WoS3 Europe PMC21998 Gong, Y., Shannon, A., Westaway, E. G., & Gowans, E. J. (1998). The replicative intermediate molecule of bovine viral diarrhoea virus contains multiple nascent strands. Archives of Virology, 143(2), 399-404.
Scopus17 WoS17 Europe PMC81998 Gong, Y., Trowbridge, R., MacKintosh, S., Shannon, A., & Gowans, E. J. (1998). A stable cell line with a proportion of cells persistently infected with bovine viral diarrhoea virus. Veterinary Microbiology, 63(2-4), 117-124.
Scopus3 WoS3 Europe PMC31998 Trowbridge, R., & Gowans, E. J. (1998). Molecular cloning of an Australian isolate of hepatitis C virus. Archives of Virology, 143(3), 501-511.
Scopus18 WoS19 Europe PMC161998 Trowridge, R., & Gowans, E. J. (1998). Identification of novel sequences at the 5′ terminus of the hepatitis C virus genome. Journal of Viral Hepatitis, 5(2), 95-98.
Scopus13 WoS13 Europe PMC101998 Hyland, C. A., Mison, L., Solomon, N., Cockerill, J., Wang, L., Hunt, J., . . . Gowans, E. J. (1998). Exposure to GB virus type C or hepatitis G virus in selected Australian adult and children populations. TRANSFUSION, 38(9), 821-827.
WoS22 Europe PMC191998 Selvey, L. A., Hyland, C. A., Mison, L., Solomon, N., & Gowans, E. J. (1998). Is there evidence for vector transmission of GBV-C?. Lancet, 351(9109), 1104-1105.
Scopus6 WoS7 Europe PMC71997 Harvey, T. J., Macnaughton, T. B., & Gowans, E. J. (1997). The development and characterisation of a SV40 T-antigen positive cell line of human hepatic origin. Journal of Virological Methods, 65(1), 67-74.
Scopus9 WoS7 Europe PMC61997 Wang, Y. H., Trowbridge, R., & Gowans, E. J. (1997). Expression and interaction of the hepatitis C virus structural proteins and the 5' untranslated region in baculovirus infected cells. Archives of Virology, 142(11), 2211-2223.
Scopus5 WoS5 Europe PMC31997 Atkins, G., Qiao, M., Coombe, D., Gowans, E., & Ashman, L. (1997). Hepatitis B virus binding to leucocyte plasma membranes utilizes a different region of the preS1 domain to the hepatocyte receptor binding site and does not require receptors for opsonins.. Immunology and Cell Biology, 75(3), 259-266.
Scopus3 WoS11996 Beardsley, A., Gowans, E., Burrell, C., & Marmion, B. (1996). Enhanced amplification of hepatitis C virus (HCV) cDNA by PCR: Detection of HCV RNA in archival sera. Journal of Clinical Microbiology, 34(6), 1581-1582.
Scopus2 WoS2 Europe PMC11996 Gong, Y., Trowbridge, R., Macnaughton, T. B., Westaway, E. G., Shannon, A. D., & Gowans, E. J. (1996). Characterization of RNA synthesis during a one-step growth curve and of the replication mechanism of bovine viral diarrhoea virus. Journal of General Virology, 77(11), 2729-2736.
Scopus73 WoS70 Europe PMC451996 Trowbridge, R., Sloots, T. P., Buda, P., Faoagali, J., Hyland, C., Young, I., & Gowans, E. J. (1996). An ELISA for the detection of antibody to the core antigen of hepatitis C virus: Use in diagnosis and analysis of indeterminate samples. Journal of Hepatology, 24(5), 532-538.
Scopus4 WoS5 Europe PMC31996 Beard, M. R., MacNaughton, T. B., & Gowans, E. J. (1996). Identification and characterization of a hepatitis delta virus RNA transcriptional promoter. Journal of Virology, 70(8), 4986-4995.
Scopus65 WoS62 Europe PMC461996 Blight, K., Trowbridge, R., & Gowans, E. J. (1996). Absence of double-stranded replicative forms of HCV RNA in liver tissue from chronically infected patients. Journal of Viral Hepatitis, 3(1), 29-36.
Scopus8 WoS8 Europe PMC31994 Qiao, M., Macnaughton, T. B., & Gowans, E. J. (1994). Adsorption and penetration of hepatitis B virus in a nonpermissive cell line. Virology, 201(2), 356-363.
Scopus39 WoS37 Europe PMC231994 MENG, Z., XU, D., SUN, D., LU, H., COPLAND, J., LIU, C., . . . GOWANS, E. J. (1994). A study of primary‐ and re‐infection with hepatitis C virus in blood transfusion recipients. Journal of Gastroenterology and Hepatology, 9(3), 211-216.
1994 McGuinness, P. H., Bishop, G. A., McCaughan, G. W., Trowbridge, R., & Gowans, E. J. (1994). False detection of negative-strand hepatitis C virus RNA. The Lancet, 343(8896), 551-552.
Scopus68 WoS68 Europe PMC181994 Beardsley, A. M., LaBrooy, J. T., Rozen, L., & Gowans, E. J. (1994). A comparison of hepatitis C virus (HCV) RNA and – antibody as markers of infection and predictors of infectivity. Australian and New Zealand Journal of Medicine, 24(2), 182-187.
Scopus10 WoS9 Europe PMC31994 MENG, Z., SUN, Y., SUN, D., LIU, C., COPLAND, J., & GOWANS, E. J. (1994). A dynamic study of viraemia in chronic hepatitis C infection. Journal of Gastroenterology and Hepatology, 9(3), 242-244.
Scopus4 WoS4 Europe PMC21994 Gowans, E. J., Blight, K., Arthur, J., & Higgins, G. D. (1994). Detection of virus nucleic acids by radioactive and nonisotopic in situ hybridization.. Methods in molecular biology (Clifton, N.J.), 33, 243-256.
Scopus1 Europe PMC11994 Gowans, E. J., Arthur, J., Blight, K., & Higgins, G. D. (1994). Application of in situ hybridization for the detection of virus nucleic acids.. Methods in molecular biology (Clifton, N.J.), 33, 395-408.
1994 Blight, K., Lesniewski, R. R., Labrooy, J. T., & Gowans, E. J. (1994). Detection and distribution of hepatitis C—specific antigens in naturally infected liver. Hepatology, 20(3), 553-557.
Scopus38 WoS44 Europe PMC251993 Gowans, E. J., & Bonino, F. (1993). Hepatitis delta virus pathogenicity.. Progress in clinical and biological research, 382, 125-130.
Scopus19 Europe PMC71993 Blight, K., Lesniewski, R., LaBrooy, J., Trowbridge, R., & Gowans, E. (1993). Localisation of hepatitis C virus proteins in infected liver tissue by immunofluorescence. Gastroenterologia Japonica, 28(5 Supplement), 55-58.
Scopus8 Europe PMC71993 Cole, S. M., Macnaughton, T. B., & Gowans, E. J. (1993). Differential roles for HDAg-p24 and -p27 in HDV pathogenesis.. Progress in clinical and biological research, 382, 131-138.
Scopus7 Europe PMC41993 Dammacco, F., Sansonno, D., Beardsley, A., & Gowans, E. J. (1993). Failure to detect hepatitis C virus (HCV) genome by polymerase chain reaction in human anti-HCV-positive intravenous immunoglobulins. Clinical and Experimental Immunology, 92(2), 205-210.
Scopus9 WoS9 Europe PMC31993 Blight, K., Rowland, R., De La Hall, P. M., Lesniewski, R. R., Trowbridge, R., LaBrooy, J. T., & Gowans, E. J. (1993). Immunohistochemical detection of the NS4 antigen of hepatitis C virus and its relation to histopathology. American Journal of Pathology, 143(6), 1568-1573.
Scopus36 WoS36 Europe PMC201993 Hardiman, R. P., Shaw, D. R., Brooy, J. T. L., Rozen, L., de Boer, W. B., Rowland, R., . . . Gowans, E. J. (1993). Chronic liver disease in asymptomatic hepatitis C antibody positive blood donors. Australian and New Zealand Journal of Medicine, 23(2), 176-180.
Scopus12 WoS14 Europe PMC51993 Macnaughton, T. B., Beard, M. R., Chao, M., Gowans, E. J., & Lai, M. M. C. (1993). Endogenous Promoters Can Direct the Transcription of Hepatitis Delta Virus RNA from a Recircularized cDNA Template. Virology, 196(2), 629-636.
Scopus37 WoS34 Europe PMC231992 Sumathy, S., Thyagarajan, S. P., Latif, R., Madanagopalan, N., Raguram, K., Rajasambandam, P., & Gowans, E. (1992). A dipstick immunobinding enzyme-linked immunosorbent assay for serodiagnosis of hepatitis B and delta virus infections. Journal of Virological Methods, 38(1), 145-152.
Scopus11 WoS11 Europe PMC71992 Gowans, E. J. (1992). Autoradiographic detection of radiolabelled probes by in situ hybridizaiton. Liver, 12(4), 238-242.
Scopus3 WoS3 Europe PMC21992 Bilght, K., Trowbridge, R., Rewland, R., & Gowans, E. (1992). Detection of hepatitis C virus RNA by in situ hybridizaiton. Liver, 12(4), 286-289.
Scopus35 WoS39 Europe PMC221992 Qiao, M., Gowans, E. J., & Burrell, C. J. (1992). Intracellular factors, but not virus receptor levels, influence the age-related outcome of DHBV infection of ducks. Virology, 186(2), 517-523.
Scopus10 WoS10 Europe PMC61992 BEARDSLEY, A. M., BLIGHT, K., GOWANS, E. J., LABROOY, J. T., ROZEN, L., & BURRELL, C. J. (1992). HEPATITIS-C VIRUS-INFECTION IN BLOOD-DONORS - EVIDENCE FOR 2 GROUPS OF ANTI-HCV-POSITIVE INDIVIDUALS. HEPATOLOGY, 16(2), 515. 1991 MacNaughton, T. B., Gowans, E. J., McNamara, S. P., & Burrell, C. J. (1991). Hepatitis δ antigen is necessary for access of hepatitis s virus rna to the cell transcriptional machinery but is not part of the transcriptional complex. Virology, 184(1), 387-390.
Scopus79 WoS82 Europe PMC571991 Gaughwin, M. D., Gowans, E., Ali, R., & Burrell, C. (1991). Bloody needles: The volumes of blood transferred in simulations of needlestick injuries and shared use of syringes for injection of intravenous drugs. AIDS, 5(8), 1025-1027.
Scopus47 WoS51 Europe PMC271991 Cole, S. M., Gowans, E. J., Macnaughton, T. B., De La M. Hall, P., & Burrell, C. J. (1991). Direct evidence for cytotoxicity associated with expression of hepatitis delta virus antigen. Hepatology, 13(5), 845-851.
Scopus73 WoS54 Europe PMC441990 Qiao, M., Gowans, E. J., Bailey, S. E., Jilbert, A. R., & Burrell, C. J. (1990). Serological analysis of duck hepatitis B virus infection. Virus Research, 17(1), 3-13.
Scopus15 WoS16 Europe PMC111990 Gowans, E. J., Macnaughton, T. B., Mickan, L., Jilbert, A. R., & Burrell, C. J. (1990). Use of recombinant hepatitis delta antigen in diagnostic assays for HDV antibody. Journal of Virological Methods, 27(1), 69-78.
Scopus4 WoS3 Europe PMC31990 Macnaughton, T. B., Gowans, E. J., Reinboth, B., Jilbert, A. R., & Burrell, C. J. (1990). Stable expression of hepatitis delta virus antigen in a eukaryotic cell line. Journal of General Virology, 71(6), 1339-1345.
Scopus39 WoS40 Europe PMC291990 Macnaughton, T. B., Gowans, E. J., Albert, A. R., & Burrell, C. J. (1990). Hepatitis delta virus RNA, protein synthesis and associated cytotoxicity in a stably transfected cell line. Virology, 177(2), 692-698.
Scopus65 WoS65 Europe PMC491990 Niu, J., Wang, Y., Qiao, M., Gowans, E., Edwards, P., Thyagarajan, S. P., . . . Locarnini, S. (1990). Effect of Phyllanthus amarus on duck hepatitis B virus replication in vivo. Journal of Medical Virology, 32(4), 212-218.
Scopus29 Europe PMC181990 Gowans, E., Macnaughton, T., & Burrel, C. (1990). Hepatitis delta virus. Today's Life Science, 2(9), 48-54. 1988 Freiman, J. S., Jilbert, A. R., Dixon, R. J., Holmes, M., Gowans, E. J., Burrell, C. J., . . . Cossart, Y. E. (1988). Experimental duck hepatitis B virus infection: Pathology and evolution of hepatic and extrahepatic infection. Hepatology, 8(3), 507-513.
Scopus61 WoS61 Europe PMC431988 FREIMAN, J. S., JILBERT, A. R., BURRELL, C. J., HOLMES, M., GOWANS, E. J., HALL, P., & COSSART, Y. E. (1988). EARLY VIRUS-CELL INTERACTIONS IN HEPADNAVIRUS INFECTION. AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 18(3), 413. 1988 Jilbert, A. R., Freiman, J. S., Burrell, C. J., Holmes, M., Gowans, E. J., Rowland, R., . . . Cossart, Y. E. (1988). Virus-liver cell interactions in duck hepatitis B virus infection. A study of virus dissemination within the liver. Gastroenterology, 95(5), 1375-1382.
Scopus38 WoS33 Europe PMC261988 Gowans, E. J., Baroudy, B. M., Negro, F., Ponzetto, A., Purcell, R. H., & Gerin, J. L. (1988). Evidence for replication of hepatitis delta virus RNA in hepatocyte nuclei after in vivo infection. Virology, 167(1), 274-278.
Scopus51 WoS51 Europe PMC421988 Korba, B. E., Gowans, E. J., Wells, F. V., Tennant, B. C., Clarke, R., & Gerin, J. L. (1988). Systemic distribution of woodchuck hepatitis virus in the tissues of experimentally infected woodchucks. Virology, 165(1), 172-181.
Scopus40 WoS41 Europe PMC311988 Gowans, E. J. (1988). Strategies for in situ hybridization. La Ricerca in Clinica e in Laboratorio, 18(2-3), 171-176.
Scopus11988 LAWSON, M. J., FOCK, K. M., GOWANS, E. J., MATHEW, T. H., & BURRELL, C. J. (1988). Hepatitis B in renal transplant recipients: An assessment of the relationship of viral replication to liver pathology. Journal of Gastroenterology and Hepatology, 3(1), 47-53.
Scopus2 WoS21987 Taylor, J., Mason, W., Summers, J., Goldberg, J., Aldrich, C., Coates, L., . . . Gowans, E. (1987). Replication of human hepatitis delta virus in primary cultures of woodchuck hepatocytes. Journal of Virology, 61(9), 2891-2895.
Scopus101 WoS110 Europe PMC701987 JILBERT, A. R., FREIMAN, J. S., BURRELL, C. J., HOLMES, M., GOWANS, E. J., ROWLAND, R., . . . COSSART, Y. E. (1987). VIRUS-CELL INTERACTIONS IN DUCK HEPATITIS-B VIRUS-INFECTION OF PEKIN-AYLESBURY DUCKS - AN INSITU STUDY OF DHBV DNA, RNA, AND DHBSAG. JOURNAL OF MEDICAL VIROLOGY, 21(4), A75-A76. 1987 FREIMAN, J., JILBERT, A., HOLMES, M., GOWANS, E., BURRELL, C., & COSSART, Y. (1987). DUCK HEPATITIS-B VIRUS - SEQUENCE AND SIGNIFICANCE OF LYMPHOID SYSTEM INFECTION. JOURNAL OF MEDICAL VIROLOGY, 21(4), A75. 1987 Jilbert, A. R., Freiman, J. S., Gowans, E. J., Holmes, M., Cossart, Y. E., & Burrell, C. J. (1987). Duck hepatitis B virus DNA in liver, spleen, and pancreas: Analysis by in situ and southern blot hybridization. Virology, 158(2), 330-338.
Scopus62 WoS55 Europe PMC451986 Jilbert, A. R., Hertzog, P. J., Burrell, C. J., Gowans, E. J., Linnane, A. W., & Marmion, B. P. (1986). Production of a monoclonal antibody to human interferon-α (IFN-α) and its use to identify IFN-α-producing cells in virus infection in vivo. Microbial Pathogenesis, 1(2), 159-168.
Scopus25 WoS29 Europe PMC221986 Jilbert, A. R., Burrell, C. J., Gowans, E. J., Hertzog, P. J., Linnane, A. W., & Marmion, B. P. (1986). Cellular localization of α‐interferon in hepatitis B virus‐infected liver tissue. Hepatology, 6(5), 957-961.
Scopus44 WoS42 Europe PMC301986 LAWSON, M. J., FOCK, K. M., GOWANS, E., MATHEW, T., & BURRELL, C. J. (1986). HEPATITIS-B IN RENAL-TRANSPLANT RECIPIENTS - AN ASSESSMENT OF THE RELATIONSHIP OF VIRAL REPLICATION TO LIVER PATHOLOGY. AUSTRALIAN AND NEW ZEALAND JOURNAL OF MEDICINE, 16(4), 597. 1986 Jilbert, A. R., Burrell, C. J., Gowans, E. J., & Rowland, R. (1986). Histological aspects of in situ hybridization - Detection of poly(A) nucleotide sequences in mouse liver sections as a model system. Histochemistry, 85(6), 505-514.
Scopus20 WoS24 Europe PMC151986 Gowans, E. J. (1986). Relationship between HBeAg and HBV DNA in patients with acute and persistent hepatitis B infection. Medical Journal of Australia, 145(9), 439-441.
Scopus19 WoS19 Europe PMC131985 Gowans, E. J., Burrell, C. J., Jilbert, A. R., & Marmion, B. P. (1985). Cytoplasmic (But not nuclear) hepatitis b virus (hbv) core antigen reflects hbv dna synthesis at the level of the infected hepatocyte. Intervirology, 24(4), 220-225.
Scopus47 WoS46 Europe PMC381985 Gowans, E. J., & Burrell, C. J. (1985). Widespread presence of cytoplasmic HBcAg in hepatitis B infected liver detected by improved immunochemical methods. Journal of Clinical Pathology, 38(4), 393-398.
Scopus46 WoS48 Europe PMC291985 Burrell, C. J., Gowans, E. J., & Marmion, B. P. (1985). HIGH LEVELS OF CYTOPLASMIC HEPATITIS B CORE ANTIGEN AS RELIABLE MARKER OF HBV DNA REPLICATION. The Lancet, 325(8426), 454-455.
Scopus9 WoS10 Europe PMC71984 Burrell, C. J., Gowans, E. J., Rowland, R., Hall, P., Jilbert, A. R., & Marmion, B. P. (1984). Correlation Between Liver Histology and Markers of Hepatitis B Virus Replication in Infected Patients: A Study by In Situ Hybridization. Hepatology, 4(1), 20-24.
Scopus56 WoS68 Europe PMC431983 Gowans, E. J., Burrell, C. J., Jilbert, A. R., & Marmion, B. P. (1983). Patterns of single- and double-stranded hepatitis B virus DNA and viral antigen accumulation in infected liver cells. Journal of General Virology, 64(6), 1229-1239.
Scopus381983 GOWANS, E. J., BURRELL, C. J., JILBERT, A. R., & MARMION, B. P. (1983). PATTERNS OF SINGLE-STRANDED AND DOUBLE-STRANDED HEPATITIS-B VIRUS-DNA AND VIRAL-ANTIGEN ACCUMULATION IN INFECTED LIVER-CELLS. JOURNAL OF GENERAL VIROLOGY, 64(JUN), 1229-1239.
WoS45 Europe PMC281982 BURRELL, C. J., GOWANS, E. J., JILBERT, A. R., LAKE, J. R., & MARMION, B. P. (1982). HEPATITIS-B VIRUS-DNA DETECTION BY INSITU CYTOHYBRIDIZATION - IMPLICATIONS FOR VIRAL REPLICATION STRATEGY AND PATHOGENESIS OF CHRONIC HEPATITIS. HEPATOLOGY, 2(2), S85-S91.
WoS371982 Burrell, C., Gowans, E., & Jilbert, A. (1982). Hepatitis B virus DNA detection by in situ cytohybridization: Implications for viral replication strategy and pathogenesis of chronic hepatitis. Hepatology, 2(2 Suppl.).
Scopus321981 Gowans, E. J., Burrell, C. J., Jilbert, A. R., & Marmion, B. P. (1981). Detection of hepatitis B virus DNA sequences in infected hepatocytes by in situ cytohybridisation. Journal of Medical Virology, 8(1), 67-78.
Scopus36 WoS38 Europe PMC231979 GOWANS, E. J., & MCNULTY, M. S. (1979). NOVEL TUBULAR AND CRYSTALLINE-STRUCTURES IN PURIFIED PREPARATIONS OF NEWCASTLE-DISEASE VIRUS. ARCHIVES OF VIROLOGY, 62(4), 353-356.
1977 MCNULTY, M. S., GOWANS, E. J., LOUZA, A. C., & FRASER, G. (1977). ELECTRON-MICROSCOPIC STUDY OF MDBK CELLS PERSISTENTLY INFECTED WITH NEWCASTLE-DISEASE VIRUS. ARCHIVES OF VIROLOGY, 53(3), 185-195.
WoS6 Europe PMC21975 MCNULTY, M. S., GOWANS, E. J., HOUSTON, M. J., & FRASER, G. (1975). NEURAMINIDASE CONTENT OF STRAINS OF NEWCASTLE-DISEASE VIRUS WHICH DIFFER IN VIRULENCE. JOURNAL OF GENERAL VIROLOGY, 27(JUN), 309-402.
WoS61973 GOWANS, E. J. (1973). IMPROVED METHOD OF AGAR PELLETED CELLS FOR ELECTRON-MICROSCOPY. MEDICAL LABORATORY TECHNOLOGY, 30(2), 113-115.
WoS5 Europe PMC4- Garcia Valtanen, P., Hope, C. M., Masavuli, M. G., Yeow, A., Balachandran, H., Mekonnen, Z. A., . . . Grubor-Bauk, B. (n.d.). 'One Year Later' - SARS-CoV-2-Specific Immunity in Mild Cases of COVID-19. -
Book Chapters
Year Citation 2017 Tomusange, K., Wijesundara, D., Gowans, E., & Grubor-Bauk, B. (2017). Human rhinovirus-A1 as an expression vector. In M. C. Ferran, & G. R. Skuse (Eds.), Recombinant Virus Vaccines: Methods and Protocols (Vol. 1581, pp. 181-201). UK: Humana Press.
2000 Burrell, C., Chisari, F., Gerlich, W., Gowans, E., Howard, C., Kann, M., & Marion, P. (2000). Taxomic Structure of the Family. In M. van Regenmortel, C. Fauquet, & D. Bishop (Eds.), Virus Taxonomy Classification and Nomenclature of Viruses (7 ed., pp. 325-334). San Diego, USA: Academic Press. -
Conference Papers
Year Citation 2013 Torresi, J., Chin, R., Chua, B., Johnson, D., Earnest-Sliveira, L., Zeng, W., . . . Jackson, D. C. (2013). HEPATITIS C VLPS DELIVERED TO DENDRITIC CELLS BY A TLR2 TARGETING LIPOPEPTIDE RESULTS IN ENHANCED NEUTRALIZING ANTIBODY AND CELL-MEDIATED RESPONSES. In JOURNAL OF HEPATOLOGY Vol. 58 (pp. S496-S497). Amsterdam, NETHERLANDS: ELSEVIER SCIENCE BV.
2008 Gowans, E. J., Jones, K. L., Latour, P. A., Chua, B. Y., Dinatale, I., Loudovaris, M., . . . Jackson, D. C. (2008). DENDRITIC CELL IMMUNOTHERAPY TO TREAT PATIENTS WITH PERSISTENT HCV INFECTION. In HEPATOLOGY Vol. 48 (pp. 1013A). San Francisco, CA: JOHN WILEY & SONS INC. 2006 Woollard, D. J., Haqshenas, G., Dong, X., & Gowans, E. J. (2006). Detection of intrahepatic virus-specific T-cells in marmosets with resolved GBV-B infection. In JOURNAL OF CLINICAL VIROLOGY Vol. 36 (pp. S16). Paris, FRANCE: ELSEVIER SCIENCE BV.
2005 Woollard, D. J., Martyn, J. C., Lee, M. L., Jones, K. L., Ffrench, R. A., & Gowans, E. J. (2005). Investigation of a novel HCV recombinant baculovirus as a vaccine delivery system. In TISSUE ANTIGENS Vol. 66 (pp. 592-593). Melbourne, AUSTRALIA: BLACKWELL PUBLISHING. 2002 Whiting, P. W., Gowans, E. J., Sloots, T. P., Mackay, I. M., Tillack, S., Harrison, M., . . . Crawford, D. H. G. (2002). The effects of vitamin B12 on hepatitis C virus replication. In GASTROENTEROLOGY Vol. 123 (pp. 74). W B SAUNDERS CO. 2000 Crawford, D. H., Lott, W. B., Cooksley, G., HArrison, M., McDonald, G., Sloots, T., & Gowans, E. J. (2000). Effects of cobalamin on hepatitis C virus translation and replication.. In HEPATOLOGY Vol. 32 (pp. 359A). W B SAUNDERS CO. 1993 ATKINS, G. J., GOWANS, E. J., & ASHMAN, L. K. (1993). HEPATITIS-B VIRUS RECEPTORS ON HEMATOPOIETIC-CELLS. In JOURNAL OF LEUKOCYTE BIOLOGY (pp. 46). FEDERATION AMER SOC EXP BIOL. 1991 MACNAUGHTON, T. B., GOWANS, E. J., QIAO, M., & BURRELL, C. J. (1991). SIMULTANEOUS EXPRESSION FROM CDNA OF MARKERS OF HEPATITIS-DELTA VIRUS AND HEPADNAVIRUS INFECTION IN CONTINUOUS CELL-LINES. In F. B. Hollinger, S. M. Lemon, & H. Margolis (Eds.), VIRAL HEPATITIS AND LIVER DISEASE (pp. 465-468). HOUSTON, TX: WILLIAMS & WILKINS.
WoS21991 Jilbert, A. R., Gowans, E. J., Macnaughton, T. B., & Burrell, C. J. (1991). Characterization of a subgenomic HDV-specific poly(A)+ RNA species isolated from human hepatoma cells supporting HDV RNA replication.. In J. L. GERIN, R. H. PURCELL, & M. RIZZETTO (Eds.), Progress in clinical and biological research Vol. 364 (pp. 309-314). WASHINGTON, DC: WILEY-LISS, INC.
Scopus6 WoS7 Europe PMC31991 Gowans, E. J., Macnaughton, T. B., Jilbert, A. R., & Burrell, C. J. (1991). Cell culture model systems to study HDV expression, replication and pathogenesis.. In J. L. GERIN, R. H. PURCELL, & M. RIZZETTO (Eds.), Progress in clinical and biological research Vol. 364 (pp. 299-308). WASHINGTON, DC: WILEY-LISS, INC.
Scopus9 WoS9 Europe PMC51987 GOWANS, E. J., BAROUDY, B. M., KORBA, B. E., & GERIN, J. L. (1987). MOLECULAR MARKERS OF WHV AND HDV INFECTION AT THE LEVEL OF THE SINGLE CELL. In JOURNAL OF CELLULAR BIOCHEMISTRY (pp. 23). WILEY-LISS. 1987 NEGRO, F., GOWANS, E., WELLS, F., HOOFNAGLE, J., BONINO, F., BAROUDY, B., & GERIN, J. (1987). AN INSITU HYBRIDIZATION ASSAY FOR HEPATITIS-DELTA-VIRUS (HDV) RNA IN LIVER AND ITS CLINICAL UTILITY AS A MARKER OF HDV REPLICATION. In JOURNAL OF HEPATOLOGY Vol. 5 (pp. S48). MUNKSGAARD INT PUBL LTD.
WoS21987 KORBA, B., TENNANT, B., GOWANS, E., WELLS, F., CLARKE, R., & GERIN, J. (1987). INFECTION AND TISSUE TROPISM OF WHV DURING THE NATURAL COURSE OF EXPERIMENTAL VIRAL-INFECTION OF WOODCHUCKS. In JOURNAL OF CELLULAR BIOCHEMISTRY (pp. 24). WILEY-LISS. 1987 BAROUDY, B. M., FUERST, T. R., GOWANS, E. J., BRANCH, A. D., ROBERTSON, H. D., WELLS, F. V., . . . GERIN, J. L. (1987). MOLECULAR-BIOLOGY OF HEPATITIS-D VIRUS. In JOURNAL OF MEDICAL VIROLOGY Vol. 21 (pp. A35). WILEY-LISS.
WoS1 -
Conference Items
Year Citation 2017 Masavuli, M. G., Wijesundara, D. K., Grubor-Bauk, B., & Gowans, E. J. (2017). Novel DNA vaccine formulations encoding secreted HCV-E1/E2 fused to the IMX313 oligomerisation domain are immunogenic in mice. Poster session presented at the meeting of 12th Annual Scientific Meeting of the Australian Centre for HIV and Hepatitis Virology. 2017 Masavuli, M. G., Wijesundara, D. K., Grubor-Bauk, B., & Gowans, E. J. (2017). Novel DNA vaccine formulations encoding secreted HCV-E1/E2 fused to the IMX313 oligomerisation domain are immunogenic in mice. Poster session presented at the meeting of Adelaide Immunology Retreat. Nuriootpa. 2017 Masavuli, M. G., Wijesundara, D. K., Grubor-Bauk, B., & Gowans, E. J. (2017). Novel DNA vaccine formulations encoding secreted HCV-E1/E2 fused to the IMX313 oligomerisation domain are immunogenic in mice. Poster session presented at the meeting of Florey Postgraduate Research Conference. 2017 Masavuli, M. G., Wijesundara, D. K., Grubor-Bauk, B., & Gowans, E. J. (2017). Enhancing the immunogenicity of HCV vaccines by fusing E1/E2 to the IMX313P multimerization technology. Poster session presented at the meeting of 24th International Symposium on Hepatitis C Virus and Related Viruses. Hyannis, Cape Cod, Massachusetts, USA. 2017 Masavuli, M. G., Wijesundara, D. K., Grubor-Bauk, B., & Gowans, E. J. (2017). Novel DNA vaccines encoding secreted HCV-E1/E2 fused to the IMX313 oligomerisation domain are immunogenic in mice. Poster session presented at the meeting of The Queen Elizabeth Hospital (TQEH) Research Day. Adeleide, Australia. 2017 Masavuli, M. G., Wijesundara, D. K., Grubor-Bauk, B., & Gowans, E. J. (2017). Enhancing the immunogenicity of HCV vaccines by fusing E1/E2 to the IMX313P oligomerisation technology. Poster session presented at the meeting of 9th Australasian Virology Society Meeting. 2016 Masavuli, M. G., Wijesundara, D. K., Grubor-Bauk, B., & Gowans, E. J. (2016). A novel DNA-based virus-like particle (VLP) vaccine against hepatitis C.. Poster session presented at the meeting of Florey Postgraduate Research Conference. 2016 Masavuli, M. G., Wijesundara, D. W., Grubor-Bauk, B., & Gowans, E. J. (2016). A DNA-based virus-like particle (VLP) vaccine against the hepatitis C virus. Poster session presented at the meeting of The Queen Elizabeth Hospital (TQEH) Research Day. Adelaide. 2016 Tomusange, K., Wijesundara, D., Gummow, J., Gowans, E. J., & Grubor-Bauk, B. (2016). Mucosal vaccination with a live recombinant rhinovirus followed by intradermal DNA administration elicits protective HIV-specific immune responses. Poster session presented at the meeting of Abstracts of the 2016 Conference on HIV Research for Prevention (HIV R4P), as published in Aids Research and Human Retroviruses. Chicago, IL: Mary Ann Liebert.
2015 Masavuli, M. G., Grubor-Bauk, B. G., Wijesundara, D. K., & Gowans, E. J. (2015). A novel DNA-based virus-like particle (VLP) vaccine for hepatitis C virus. Poster session presented at the meeting of Florey Postgraduate Research Conference. AdelaIide. 2015 Masavuli, M. G., Wijesundara, D. K., grubor-bauk, B., & gowans, E. G. (2015). A novel DNA-based virus-like particle vaccine for hepatitis C virus. Poster session presented at the meeting of The Queen Elizabeth Hospital (TQEH) Research Day 2015. Adelaide. 2013 Loveland, B. E., Latour, P., Roberts, S. K., Gordon, A., Kemp, W., Kitson, M., . . . Gowans, E. J. (2013). A Phase I clinical trial of cellular immunotherapy for persistent Hepatitis C infection. Poster session presented at the meeting of Clinical and Experimental Pharmacology and Physiology. Hangzhou, Peoples Republic of China: Wiley-Blackwell. -
Theses
Year Citation 2018 Masavuli, M. G. (2018). Novel DNA Vaccine Formulations Against
Hepatitis C Virus. (PhD Thesis).
Grants and Funding
2009-2011 | A novel HCV vaccine |
EJ Gowans, B Loveland |
NHMRC |
$151,000 pa |
2009-2011 | A new HCV cell therapy |
EJ Gowans, SK Roberts, B Loveland |
NHMRC |
$164,749 pa |
2008-2009 | A replication defective vaccine strategy for HCV. |
EJ Gowans, B Loveland, J Torresi, S Li |
ACH2 | $110,000 pa |
2011-13 | A vaccine for hepatitis C virus. |
EJ Gowans, J Torresi, S Das |
Australia-India Biotechnology Fund | $100,000 pa |
2012-2014 | Mucosal immunity to HIV |
EJ Gowans, A Suhrbier, S Wesselingh |
NHMRC | $188,000 pa |
2012-13 | Development of a cytolytic HCV vaccine and a novel challenge model to test efficacy | E J Gowans, B Grubor-Bauk | ACH2 | $174,000 |
2014-15 | DNA vaccine therapy for HCV | E J Gowans, I Roberts-Thomson, B Grubor-Bauk | THRF | $300,000 |
2014 | Optimisation of HCV vaccine design | E J Gowans, B Grubor-Bauk | THRF | $100,000 |
2014-16 | A quadrivalent vaccine for hepatitis C | Joseph Torresi, E J Gowans | NHMRC | $450,000 |
2015-16 | Approaches to develop an effective HCV vaccine | E J Gowans, J Torresi, S Das | AISRF | $200,000 |
2016-17 | A DNA vaccine to induce protective neutralizing antibodies to the HIV Tat protein | E J Gowans | THRF | $160,000 |
2017 | A multigenotypic HCV DNA vaccine | E J Gowans, B Grubor-Bauk, D Wijesundara | ACH2 | $85,000 |
2016-2018 | A DNA vaccine for Zika virus |
E J Gowans, B Grubor-Bauk, D Wijesundara |
NFMRI | $293,880 |
Teaching and Supervision
1964 - 1969 | Preparation of materials for medical and science student practical classes and for the preparation of demonstrations. |
1972 - 1975 | Part-time demonstrator and tutor, Napier College, Edinburgh, to teach Medical Microbiology in the Higher National Certificate Course. |
1984 - 1988 | Lecturer and demonstrator in Virology teaching programme provided by the Division of Medical Virology, IMVS, to Science, Dental and Medical Students in the University of Adelaide. |
1988 - 1993 | Formal appointment as Visiting Lecturer, Department of Microbiology and Immunology, University of Adelaide. Responsible for organisation of Virology Honours course. |
1994-1997 | Honorary Reader, Department of Microbiology, University of Queensland. |
1996-2002 | Assoc. Professor, Department of Paediatrics, University of Queensland. |
1997-2002 | Adjunct Professor, Department of Microbiology, University of Queensland. |
2003-2012 | Honorary Professor, Dept of Microbiology, Monash University |
2009- | Honorary Professor, University of Adelaide. |
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Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2015 - 2019 Principal Supervisor Pre-Clinical Evaluation of a Vaccination Strategy to Induce Liver Resident Memory T Cells against Hepatitis C Virus Doctor of Philosophy Doctorate Full Time Mr Zelalem Addis Mekonnen 2015 - 2016 Principal Supervisor Strategies for the development of recombinant porcine adenovirus-based vaccines against Hepatitis C virus. Master of Philosophy (Medical Science) Master Full Time Mr Harshwardhan Jagdale 2014 - 2018 Principal Supervisor Novel DNA Vaccine Formulations Against Hepatitis C Virus Doctor of Philosophy Doctorate Full Time Dr Makutiro Ghislain Masavuli 2013 - 2016 Principal Supervisor Novel Recombinant DNA and Live Virus Vaccines to Prevent or Control HIV-1 Infection Doctor of Philosophy Doctorate Full Time Mr Khamis Tomusange 2012 - 2014 Principal Supervisor Evaluating the Immuno-modulatory Effects of a Natural Adjuvant as a Novel Vaccine Strategy Doctor of Philosophy Doctorate Full Time Miss Tamsin Jade Garrod 2012 - 2013 Principal Supervisor Optimising DNA vaccine technology to prevent HIV-1 Infection Doctor of Philosophy Doctorate Full Time Miss Tessa Gargett 2012 - 2017 Principal Supervisor The Development of a Multi-Antigenic Cytolytic DNA Vaccine against HCV Doctor of Philosophy Doctorate Full Time Dr Jason Anthony Gummow 2010 - 2012 Principal Supervisor Suicide Genes in a Novel Vaccination Strategy for Hepatitis C Master of Philosophy Master Full Time Mr Hugh Francis Trahair
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Committee Memberships
Date Role Committee Institution Country 2015 - ongoing Member NHMRC Grant Assigner’s Panel - - 2012 - ongoing Chair Strategic Research Directions Committee Basil Hetzel Institute, The Queen Elizabeth Hospital - 2012 - ongoing Member BHI Policy Committee - - 2012 - ongoing Member Local organising committee Australian-Pacific Congress of Virology - 2012 - ongoing Member Microbiology Grant Review Panel NHMRC - 2012 - 2014 Member Advisory Committee for Biologicals, Therapeutic Goods Administration - - 2005 - ongoing Chair Institutional Biosafety Committee The Queen Elizabeth Hospital and Basil Hetzel Institute Australia -
Memberships
Date Role Membership Country 2014 - ongoing - Virus Research - 1999 - ongoing - Journal of Gastroenterology and Hepatology - 1998 - ongoing - Virus Genes - -
Consulting/Advisories
Date Institution Department Organisation Type Country 2012 - ongoing Viralytics Ltd - - -
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