Dr Emmanuel Gnanamanickam

Senior Research Fellow

Office of Health

College of Health


Emmanuel is a human services researcher with emerging expertise in both health economics and big data, working with linked administrative and electronic health record data. Specifically, he has expertise in costing health service utilisation and residential aged care based on national best practice. His health services research has spanned, maternal and neonatal health, oral health, dementia and aged care and currently, cardiology and child protection.
He has worked across all three universities in South Australia and SA Health, consequently having established networks across the health and social research sector in South Australia and beyond. He welcomes the opportunity to collaborate with anyone looking to add an economic element to thier health research project in specific but health economics more broadly. 
He completed his PhD in 2016 examining the cost-effectiveness of dental insurance and has masters level qualifications in both public health and social work. His previous work includes oral health promotion, primary health service management among indigenous groups, second stage tsunami rehabilitation, and migrant health.

iCAN = Impacts of Child Abuse & Neglect. With evidence we can change Life Trajectories 

Aim: Describe and measure the consequences of child abuse and neglect and the factors that might disrupt or exacerbate child maltreatment perpetuation (including intergenerational transmission).

Study design: Longitudinal whole of population cohort study – drawing on linked administrative data.

Theoretical underpinning:  A deep understanding of the causes and consequences of child maltreatment guides the research questions and analysis plans. The theory draws on neurobiology, attachment theory, trauma theory and ethology, that highlights the impacts of relational trauma and toxic childhood environments of child abuse and neglect on the developing brain and thus thinking, emotions, behaviours and relational patterning. 

Study Population: All person born in SA between 1986 and 31 December 2017 > 608,000 persons, including 40,000 mother-child pairs (where the mothers were cohort members).

Linked data sets:

Child Protection:Notifications, Investigations, Substantiations, Out-of-home care, Court orders, Harms grounds, etc.Education and child development

Schools census: enrolment year, absenteeism, problem behaviours, disability, basic parental information, etc.NAPLAN (numeracy and literacy test grades 5, 7, 9)AEDC (Australian early development census) - child emotional, behavioural, interpersonal and physical development at school commencement.  

Health/health services: Hospital in-patient, Emergency Department

Deaths - SA Death Registry, National Coronial Information System

Midwives: Perinatal data set

Under request

Centrelink income support data

National Death Index

Collaborative opportunities: The iCAN data set has taken some 10 years to create. It is now a world class linked-data set able to leverage research on a wide range of high-profile public health and social policy questions. In particular questions related to family violence against children, the role of other child, family and community factors and how the child protection and wider service system might ameliorate or exacerbate harms. Opportunities for collaboration are extensive. Please contact the CI Prof. Leonie Segalor myself

Broad findings to date

The work is producing world first population-based estimates of the impact of child maltreatment – across many birth cohorts and with contemporaneous assessment of likely child maltreatment exposure and potential confounders, made possible by the use of linked administrative data on a large birth cohort, born from 1986 to end 2017, of 608,000 persons. As compared with survey-based studies, it means this work will better represent those most damaged by child abuse and neglect, often missing from surveys; such as those who die young or suffer serious injury or major mental health problems. Interestingly the relative risks identified by the iCAN study suggest even greater damage from child abuse and neglect than generally reported.

  • Every outcome explored to date, without exception across health (including premature death), health service use, educational and developmental, child maltreatment exposure as indicated by child protection system involvement increases the risk of poor outcomes – across the life course from infancy through adulthood (to 30+ year-olds). 
  • Differential risk is large – typically 2+ times risk of poor outcome with persons exposed to child maltreatment relative to those with no such exposure; after adjusting for potential child, parental and socioeconomic confounders.
  • Risk of a poor outcome typically escalates with categories of child protection system contact indicative of more serious / higher certainty of child maltreatment exposure.
  • In terms of intergenerational transmission. The likelihood that a mother with child maltreatment  exposure will have a child with child protection system contact, the risk ratios are even higher and especially for the more serious child maltreatment concerns.
  • The impact of child protection system contact on on-going child maltreatment exposure and consequences across the life course is as yet poorly understood and requires additional research. 

Press releases for our work can be accessed here: https://www.unisa.edu.au/Media-Centre/Releases/?q=iCAN

Date Position Institution name
2023 - ongoing Senior Research Fellow University of Adelaide
2022 - ongoing Epidemiologist Royal Adelaide Hospital
2019 - 2022 Research Fellow (Adjunct) South Australian Health and Medical Research Institute
2019 - ongoing Academic Status Flinders University
2018 - ongoing Research Fellow University of South Australia
2017 - 2018 Research Fellow Flinders University
2017 - 2022 Data Manager Flinders Medical Centre
2017 - 2021 Visiting Fellow University of Adelaide
2011 - 2016 Research Officer University of Adelaide

Language Competency
English Can read, write, speak, understand spoken and peer review
Malayalam Can speak
Tamil Can read, write, speak and understand spoken

Date Institution name Country Title
2016 University of Adelaide Australia PhD
2010 University of Sheffield United Kingdom Master of Public Health
2010 University of Copenhagen Denmark Master of Public Health
2004 Madras Christian College (University of Madras) India Master of Social Work
2002 Madras Christian College (University of Madras) India Bachelor of Commerce

Date Title Institution name Country
2020 CHIA Australian Institute of Digital Health -

Year Citation
2025 Gnanamanickam, E. S., Nguyen, H., Armfield, J. M., Doidge, J. C., Brown, D. S., Preen, D. B., & Segal, L. (2025). Hospitalizations among children involved in the child protection system: a long-term birth cohort study from infancy to adulthood using administrative data. Child Abuse and Neglect, 107(104518), 104518-1-104518-14.
DOI Scopus15 WoS16 Europe PMC10
2025 Hammat, A. S., Gnanamanickam, E. S., Cho, C. H., Ramasamy, B., Nelson, R., Campbell, D., . . . Callary, S. A. (2025). Diagnosis and Treatment Influence Hospital Costs of Revision Total Hip Arthroplasty: A Systematic Review and Meta-Analysis.. J Arthroplasty, 40(9), 2423-2431.e2.
DOI Scopus2 WoS2 Europe PMC2
2025 Nadkarni, A., Besic, N., Yap, J., Micik, S., Chapple, L. -A. S., Gnanamanickam, E., . . . Farquharson, M. (2025). Rationalising arterial blood gas sampling analysis in the intensive care unit: A before-and-after study. Australian Critical Care, 38(4), 101237.
DOI
2025 Hammat, A. S., D'Apollonio, T., Nelson, R., Campbell, D., Ramasamy, B., Solomon, L. B., . . . Callary, S. A. (2025). The higher hospital costs of revision total hip arthroplasty by diagnosis: analysis of cost drivers and periprosthetic joint infection treatment pathways. ANZ Journal of Surgery, online, 1-9.
DOI
2024 Hammat, A. S., Nelson, R., Davis, J. S., Manning, L., Campbell, D., Solomon, L. B., . . . Callary, S. A. (2024). Estimation of two-year hospital costs of hip and knee periprosthetic joint infection treatments using activity-based costing. Bone and Joint Journal, 106 B(10), 1084-1092.
DOI Scopus9 Europe PMC2
2024 Segal, L., & Gnanamanickam, E. S. (2024). The Australian Child Maltreatment Study: National prevalence and associated health outcomes of child abuse and neglect.. The Medical journal of Australia, 220(5), 275.
DOI Scopus2 WoS3 Europe PMC2
2024 Batty, G. D., Kivimäki, M., Almquist, Y. B., Eriksson, J. G., Gissler, M., Gnanamanickam, E. S., . . . Frank, P. (2024). Cardiovascular Disease Events in Adults with a History of State Care in Childhood: Pooling of Unpublished Results from 9 Cohort Studies.. medRxiv.
DOI
2024 Lanais, K., Gnanamanickam, E., Maclean, M., & Segal, L. (2024). Investigating the impact of Out-of-Home Care on early childhood development. Child Abuse and Neglect, 154(106856), 106856-1-106856-11.
DOI Scopus4 WoS4 Europe PMC2
2024 Jones, K. A., Henderson, H., Bright, T., Segal, L., Mauerhofer, O., Lake, K. J., . . . Chamberlain, C. (2024). Healing the Past by Nurturing the Future: trauma-aware, healing-informed care to improve support for Aboriginal and Torres Strait Islander families - implementation and evaluation study protocol. BMJ Open, 14(7), e085555-1-e085555-10.
DOI
2024 Gnanamanickam, E. S., & Segal, L. (2024). Receipt of parenting, disability, unemployment, and other income support payments in persons aged 16 to 33 years - the associations with child maltreatment. Child Abuse and Neglect, 154, 106925-1-106925-10.
DOI Scopus2 WoS1
2024 Batty, G. D., Kivimäki, M., Almquist, Y. B., Eriksson, J. G., Gissler, M., Gnanamanickam, E. S., . . . Frank, P. (2024). Cardiovascular disease in adults with a history of out-of-home care during childhood: a systematic review and meta-analysis of prospective cohort studies. The Lancet Regional Health - Europe, 43(100984), 100984.
DOI Scopus1 WoS1
2023 Gnanamanickam, E. S., Brown, D. S., Armfield, J. M., & Segal, L. (2023). Excess hospital costs incurred by individuals with child abuse and neglect history in South Australia: A birth-cohort study. Preventive Medicine, 166(article no.107378), 107378-1-107378-8.
DOI Scopus6 WoS6 Europe PMC2
2023 Segal, L., Dawe, S., Nguyen, H., Dennison, S., Gnanamanickam, E. S., Bell, M., . . . Preen, D. B. (2023). Child protection system involvement in children of incarcerated mothers: A linked data study. Child Abuse and Neglect, 139(106126), 106126.
DOI Scopus4 WoS4
2023 Tan, J. Y., Chew, D. P., Lambrakis, K., Tiver, K. D., Gnanamanickam, E. S., Muthuranjan, C., . . . De Pasquale, C. G. (2023). Sodium-Glucose Cotransporter 2 Inhibitors in South Australia: The Magic Before the Fame.. Heart Lung Circ, 32(11), 1369-1377.
DOI
2022 Gnanamanickam, E. S., Nguyen, H., Armfield, J. M., Doidge, J. C., Brown, D. S., Preen, D. B., & Segal, L. (2022). Child maltreatment and emergency department visits: a longitudinal birth cohort study from infancy to early adulthood. Child Abuse and Neglect, 123(105397), 105397-1-105397-11.
DOI Scopus16 WoS16 Europe PMC12
2022 Chuang, M. Y. A., Gnanamanickam, E. S., Karnon, J., Lambrakis, K., Horsfall, M., Blyth, A., . . . Chew, D. P. (2022). Cost effectiveness of a 1-hour high-sensitivity troponin-T protocol: an analysis of the RAPID-TnT trial. IJC Heart and Vasculature, 38, 1-8.
DOI Scopus11 WoS9 Europe PMC6
2021 Armfield, J. M., Gnanamanickam, E. S., Johnston, D. W., Preen, D. B., Brown, D. S., Nguyen, H., & Segal, L. (2021). Intergenerational transmission of child maltreatment in South Australia, 1986-2017: a retrospective cohort study. The Lancet Public Health, 6(7), e450-e461.
DOI Scopus46 WoS45 Europe PMC26
2021 Segal, L., Doidge, J., Armfield, J. M., Gnanamanickam, E. S., Preen, D. B., Brown, D. S., & Nguyen, H. (2021). Association of child maltreatment with risk of death during childhood in South Australia. JAMA Network Open, 4(6), 1-13.
DOI Scopus13 WoS12 Europe PMC7
2021 Armfield, J. M., Ey, L. A., Zufferey, C., Gnanamanickam, E. S., & Segal, L. (2021). Educational strengths and functional resilience at the start of primary school following child maltreatment. Child Abuse and Neglect, 122(105301), 105301-1-105301-12.
DOI Scopus12 WoS11 Europe PMC6
2021 Segal, L., Armfield, J. M., Gnanamanickam, E. S., Preen, D. B., Brown, D. S., Doidge, J., & Nguyen, H. (2021). Child Maltreatment and Mortality in Young Adults.. Pediatrics, 147(1, article no. e2020023416), e2020023416.
DOI Scopus55 WoS56 Europe PMC38
2020 Armfield, J. M., Gnanamanickam, E., Nguyen, H. T., Doidge, J. C., Brown, D. S., Preen, D. B., & Segal, L. (2020). School absenteeism associated with child protection system involvement, maltreatment type, and time in out-of-home care. Child Maltreatment, 25(4), 433-445.
DOI Scopus18 WoS17 Europe PMC6
2020 Crotty, M., Gnanamanickam, E. S., Cameron, I., Agar, M., Ratcliffe, J., & Laver, K. (2020). Are people in residential care entitled to receive rehabilitation services following hip fracture? Views of the public from a citizens' jury. BMC Geriatrics, 20(1), 172-1-172-8.
DOI Scopus9 WoS9 Europe PMC7
2020 Gnanamanickam, E. S., Dyer, S. M., Harrison, S. L., Liu, E., Whitehead, C., & Crotty, M. (2020). Associations between cognitive function, hospitalizations and costs in nursing homes: a cross-sectional study. Journal of Aging and Social Policy, 34(4), 552-567.
DOI Scopus4 WoS4 Europe PMC4
2019 Segal, L., Nguyen, H., Mansor, M. M., Gnanamanickam, E., Doidge, J. C., Preen, D. B., . . . Armfield, J. M. (2019). Lifetime risk of child protection system involvement in South Australia for Aboriginal and non-Aboriginal children, 1986–2017 using linked administrative data. Child Abuse and Neglect, 97(104145), 104145-1-104145-11.
DOI Scopus27 WoS26 Europe PMC16
2019 Harrison, S. L., Dyer, S. M., Milte, R., Liu, E., Gnanamanickam, E. S., & Crotty, M. (2019). Alternative staffing structures in a clustered domestic model of residential aged care in Australia. Australasian Journal on Ageing, 38(S2), 68-74.
DOI Scopus6 WoS5 Europe PMC3
2019 Amarasena, N., Gnanamanickam, E. S., & Miller, J. (2019). Effects of interdental cleaning devices in preventing dental caries and periodontal diseases: a scoping review.. Australian dental journal, 64(4), 327-337.
DOI Scopus29 WoS25 Europe PMC19
2019 S Gnanamanickam, E., M Dyer, S., Milte, R., Liu, E., Ratcliffe, J., & Crotty, M. (2019). Clustered domestic model of residential care is associated with better consumer rated quality of care. International Journal for Quality in Health Care, 31(6), 419-425.
DOI Scopus10 WoS9 Europe PMC6
2019 Liu, E., Dyer, S. M., Whitehead, C., O'Donnell, L. K., Gnanamanickam, E. S., Harrison, S. L., . . . Crotty, M. (2019). Patterns of medication prescription by dementia diagnosis in Australian nursing home residents: a cross-sectional study. Journal of Pharmacy Practice and Research, 49(1), 33-40.
DOI Scopus6
2018 Dyer, S. M., Gnanamanickam, E. S., Liu, E., Whitehead, C., & Crotty, M. (2018). Diagnosis of dementia in residential aged care settings in Australia: an opportunity for improvements in quality of care?. Australasian Journal on Ageing, 37(4), E155-E158.
DOI Scopus34 WoS33 Europe PMC29
2018 Gnanamanickam, E., Dyer, S., Milte, R., Harrison, S., Liu, E., Easton, T., . . . Crotty, M. (2018). Direct health and residential care costs of people living with dementia in Australian residential aged care. International Journal of Geriatric Psychiatry, 33(7), 859-866.
DOI Scopus35 WoS31 Europe PMC29
2018 Harrison, S., Kouladjian O Donnell, L., Bradley, C., Milte, R., Dyer, S., Gnanamanickam, E., . . . Crotty, M. (2018). Associations between the Drug Burden Index, potentially inappropriate medications and quality of life in residential aged care. Drugs and Aging, 35(1), 83-91.
DOI Scopus51 WoS45 Europe PMC40
2018 Harrison, S., Kouladjian O'Donnell, L., Milte, R., Dyer, S., Gnanamanickam, E., Bradley, C., . . . Crotty, M. (2018). Costs of potentially inappropriate medication use in residential aged care facilities. BMC Geriatrics, 18(1), 9-1-9-10.
DOI Scopus70 WoS66 Europe PMC52
2018 Dyer, S., Liu, E., Gnanamanickam, E., Milte, R., Easton, T., Harrison, S., . . . Crotty, M. (2018). Clustered domestic residential aged care in australia: fewer hospitalisations and better quality of life. Medical Journal of Australia, 208(10), 433-438.
DOI Scopus47 WoS44 Europe PMC30
2018 Laver, K., Gnanamanickam, E., Whitehead, C., Kurrle, S., Corlis, M., Ratcliffe, J., . . . Crotty, M. (2018). Introducing consumer directed care in residential care settings for older people in Australia: Views of a citizens’ jury. Journal of Health Services Research and Policy, 23(3), 176-184.
DOI Scopus3 WoS4 Europe PMC2
2018 Oral Presentations (2018). Australasian Journal on Ageing, 37(S2), 20-48.
DOI
2017 Laver, K., Gnanamanickam, E., Ratcliffe, J., Shulver, W., Cameron, I., Agar, M., & Crotty, M. (2017). A CITIZENS JURY TO INFORM POLICY ON REHABILITATION FOR PEOPLE IN RESIDENTIAL CARE WITH HIP FRACTURE. Innovation in Aging, 1(suppl_1), 226.
DOI
2017 Liu, E., Dyer, S. M., O'Donnell, L. K., Milte, R., Bradley, C., Harrison, S. L., . . . Crotty, M. (2017). Association of cardiovascular system medications with cognitive function and dementia in older adults living in nursing homes in Australia. Journal of Geriatric Cardiology, 14(6), 407-415.
DOI Scopus14 WoS13 Europe PMC11
2017 Gnanamanickam, E., Teusner, D., Arrow, P., & Brennan, D. (2017). Dental insurance, service use and health outcomes in Australia: a systematic review. Australian Dental Journal, 63(1), 4-13.
DOI Scopus32 WoS29 Europe PMC22
2017 Teusner, D., Smith, V., Gnanamanickam, E., & Brennan, D. (2017). Examining dental expenditure and dental insurance accounting for probability of incurring expenses. Community Dentistry and Oral Epidemiology, 45(2), 101-111.
DOI Scopus8 WoS7 Europe PMC7
2013 Teusner, D., Brennan, D., & Gnanamanickam, E. (2013). Individual dental expenditure by Australian adults. Australian Dental Journal, 58(4), 498-506.
DOI Scopus10 WoS10 Europe PMC7

Year Citation
2021 Chuang, A., Gnanamanickam, E., Lambrakis, K., Horsfall, M., Karnon, J., Blyth, A., . . . Chew, D. P. (2021). Cost Effectiveness of a 1-Hour High-Sensitivity Troponin-t Protocol in Suspected Acute Coronary Syndrome: A Trial-Based Analysis of the Rapid-tnt Randomised Trial. In CIRCULATION Vol. 144 (pp. 3 pages). MA, Boston: LIPPINCOTT WILLIAMS & WILKINS.

Year Citation
2018 Harrison, S., Dyer, S., O'Donnell, L. K., Milte, R., Gnanamanickam, E., Hilmer, S., . . . Crotty, M. (2018). Increased drug burden and potentially inappropriate medication use associates with hospitalisations in older people living in residential care. Poster session presented at the meeting of AUSTRALASIAN JOURNAL ON AGEING. WILEY.
2018 Dyer, S., Gnanamanickam, E., Liu, E., Whitehead, C., & Crotty, M. (2018). Lack of dementia diagnosis in Australian residential aged care - an opportunity for improvements in quality of care?. Poster session presented at the meeting of AUSTRALASIAN JOURNAL ON AGEING. WILEY.
2014 Gnanamanickam, E. S., Teusner, D. N., & Brennan, D. S. (2014). Oral health and its relationship with prospective dental service use. Poster session presented at the meeting of Programme and Abstract Book 54th Annual Scientific Meeting of the International Association for Dental Research. Brisbane, Queensland, Australia.

Year Citation
2016 Gnanamanickam, E. S. (2016). Dental insurance, dental service use and health outcomes: effectiveness and cost-effectiveness among Australian adults. (PhD Thesis, University of Adelaide).

Year Citation
2024 Chamberlain, C., Sundbery, J., Segal, L., Krakouer, J., Langton, M., Donnelly, J., . . . Marriott, R. (2024). Replanting the Birthing Trees to Support Aboriginal and Torres Strait Islander Parents and Babies: Protocol for developmental evaluation of a comprehensive culturally responsive, trauma-aware, healing-informed, continuity of care(r) model.
DOI
2024 Batty, G. D., Kivimäki, M., Almquist, Y. B., Eriksson, J. G., Gissler, M., Gnanamanickam, E., . . . Frank, P. (2024). Cardiovascular Disease Events in Adults with a History of State Care in Childhood: Pooling of Unpublished Results from 9 Cohort Studies.
DOI
2019 Dyer, S. M., Liu, E., Gnanamanickam, E., Harrison, S. L., Milte, R., & Crotty, M. (2019). People living in residential aged care need to BE outside not just SEE outside: associations between quality of life and outdoor access: a cross-sectional study.
DOI Europe PMC1
  • Relighting the firesticks: Accelerating diffusion and progressing to sustainability of innovative care to foster a healthy start to life for Aboriginal and Torres Strait Islander families, MRFF Early to Mid-Career Researchers Grant, 01/03/2024 - 31/10/2029

Date Role Research Topic Program Degree Type Student Load Student Name
2023 External Supervisor Cost Analysis of Revision Total Hip Replacement Doctor of Philosophy Doctorate Full Time Mr Aaron Scott Hammat

Date Role Research Topic Location Program Supervision Type Student Load Student Name
2023 - ongoing Co-Supervisor Children with substantiated child maltreatment – What is the effect of removal to alternate (out-of-home) care during early childhood? University of South Australia Doctor of Philosophy Doctorate Full Time Ms Krystal Lanais
2022 - 2022 Co-Supervisor Investigating the Impact of Out-of-Home Care on Early Childhood Development: A Propensity-Matched Study University of South Australia Psychology Honours Honours Full Time Ms Krystal Lanais

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