Researcher Profiles

Dr Emily Mackie

Postdoctoral Researcher

Waite Research Institute

Division of Research and Innovation

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.

Career
Publications
Grants and Funding
Supervision
Contact

Appointments

Date Position Institution name

2023 - ongoing Grant-Funded Researcher (A) Waite Research Institute

Education

Date	Institution name	Country	Title
2023	University of Adelaide	Australia	PhD
2018	La Trobe University	Australia	Master of Biotechnology and Bioinformatics
2015	La Trobe University	Australia	Bachelor of Biomedical Science

Journals

Year	Citation
2025	Antoney, J., Kainrath, S., Dubowsky, J. G., Ahmed, F. H., Kang, S. W., Mackie, E. R. R., . . . Janovjak, H. (2025). A F420-dependent single domain chemogenetic tool for protein de-dimerization. Journal of Molecular Biology, 437(17), 169184-1-169184-17. DOI
2025	Mackie, E. R. R., Mckay, M. V., Barrow, A. S., & da Costa, T. P. S. (2025). Inhibitors of lysine biosynthesis enzymes as potential new herbicides. Functional Plant Biology, 52(5), FP25030-1-FP25030-13. DOI
2023	Javorsky, A., Maddumage, J. C., Mackie, E. R. R., Soares da Costa, T. P., Humbert, P. O., & Kvansakul, M. (2023). Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 PBM. The FEBS journal, 290(4), 974-987. DOI Scopus9 WoS9 Europe PMC9
2023	Mackie, E. R. R., Barrow, A. S., Giel, M. -C., Hulett, M. D., Gendall, A. R., Panjikar, S., & Soares da Costa, T. P. (2023). Repurposed inhibitor of bacterial dihydrodipicolinate reductase exhibits effective herbicidal activity. Communications Biology, 6(1), 1-11. DOI Scopus3 WoS3 Europe PMC3
2022	Mackie, E. R. R., Barrow, A. S., Christoff, R. M., Abbott, B. M., Gendall, A. R., & Soares da Costa, T. P. (2022). A dual-target herbicidal inhibitor of lysine biosynthesis. eLife, 11, 1-11. DOI Scopus8 WoS7 Europe PMC5
2022	Teakel, S., Marama, M., Aragao, D., Tsimbalyuk, S., Mackie, E. R. R., da Costa, T. P. S., . . . Cahill, M. A. (2022). Structural characterisation of a MAPR-related archaeal cytochrome b(5M) protein. FEBS Letters, 596(18), 2409-2417. DOI Scopus3 WoS3 Europe PMC2
2021	Nonis, S. G., Haywood, J., Schmidberger, J. W., Mackie, E. R. R., Soares da Costa, T. P., Bond, C. S., & Mylne, J. S. (2021). Structural and biochemical analyses of concanavalin A circular permutation by jack bean asparaginyl endopeptidase. Plant Cell, 33(8), 2794-2811. DOI Scopus23 WoS20 Europe PMC16
2020	Li, Z., MacKie, E. R. R., Ramkissoon, P., Mather, J. C., Wiratpruk, N., Soares Da Costa, T. P., & Barnard, P. J. (2020). Synthesis, conformational analysis and antibacterial activity of Au(I)-Ag(I) and Au(I)-Hg(II) heterobimetallic N-heterocyclic carbene complexes. Dalton Transactions, 49(36), 12820-12834. DOI Scopus13 WoS14 Europe PMC7
2020	Hall, C. J., Mackie, E. R. R., Gendall, A. R., Perugini, M. A., & Soares da Costa, T. P. (2020). Review: amino acid biosynthesis as a target for herbicide development. Pest Management Science, 76(12), 3896-3904. DOI Scopus25 WoS20 Europe PMC16
2020	Giel, M. C., Smedley, C. J., Mackie, E. R. R., Guo, T., Dong, J., Soares da Costa, T. P., & Moses, J. E. (2020). Metal-Free Synthesis of Functional 1-Substituted-1,2,3-Triazoles from Ethenesulfonyl Fluoride and Organic Azides. Angewandte Chemie - International Edition, 59(3), 1181-1186. DOI Scopus76 WoS74 Europe PMC30

Preprint

Year	Citation
2022	Antoney, J., Kainrath, S., Ahmed, H., Kang, S. W., Mackie, E., Soares da Costa, T., . . . Janovjak, H. (2022). A F<sub>420</sub>-dependent single domain chemogenetic tool for protein de-dimerization. DOI
2022	Mackie, E., Barrow, A., Christoff, R., Abbott, B., Gendall, A., & Soares da Costa, T. (2022). A dual-target herbicidal inhibitor of lysine biosynthesis. DOI
2019	Giel, M. -C., Smedley, C., Mackie, E., Guo, T., Dong, J., Costa, T. S. D., & Moses, J. (2019). Metal-Free Click Synthesis of Functional 1-Substituted-1,2,3-Triazoles. DOI

Date	Project	Funding Body	Role	Amount
2025-2028	Learning lessons from drug resistance to tackle herbicide resistance	Australian Research Council Discovery Project	Investigator	$666,653
2025	Investigating a novel mediator of plant-to-plant communication	Elizabeth MacMeikan Trust (University of Adelaide)	Chief Investigator	$11,210
2025	Towards a novel strategy to mitigate herbicide resistance spread	Faculty of SET EMCR Grant (University of Adelaide)	Chief Investigator	$10,000
2023	Engineering plants to reverse herbicide resistance in weeds	Charlick Fund (University of Adelaide)	Chief Investigator	$11,133
2022-2025	Novel diagnostic tools to monitor and combat herbicide resistance	Hermon Slade Foundation	Investigator	$77,842
2019-2022	Development of herbicide cocktails with a novel mode of action for circumventing resistance mechanisms	Grains Research and Development Corporation	Investigator	$107,091

Current Higher Degree by Research Supervision (University of Adelaide)

Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
2025	Co-Supervisor	Targeted Herbicide Development: Exploring Novel Modes of Action to Combat Resistance	Doctor of Philosophy	Doctorate	Full Time	Ms Lilitha Njobe

Other Supervision Activities

Date	Role	Research Topic	Location	Program	Supervision Type	Student Load	Student Name
2024 - ongoing	Co-Supervisor	A dual-pronged approach to tackling herbicide resistance	University of Adelaide	-	Honours	Full Time	Eloise Hart

Position: Postdoctoral Researcher
Email: emily.mackie@adelaide.edu.au
Campus: Waite
Org Unit: School of Agriculture, Food and Wine

Connect With Me

External Profiles