Emily Mackie

Dr Emily Mackie

Internal Grant-Funded Researcher (A)

School of Agriculture, Food and Wine

College of Sciences

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.

Date Position Institution name
2023 - ongoing Grant-Funded Researcher (A) Waite Research Institute

Date Institution name Country Title
2023 University of Adelaide Australia PhD
2018 La Trobe University Australia Master of Biotechnology and Bioinformatics
2015 La Trobe University Australia Bachelor of Biomedical Science

Year Citation
2025 Antoney, J., Kainrath, S., Dubowsky, J. G., Ahmed, F. H., Kang, S. W., Mackie, E. R. R., . . . Janovjak, H. (2025). A F420-dependent single domain chemogenetic tool for protein de-dimerization. Journal of Molecular Biology, 437(17), 169184-1-169184-17.
DOI
2025 Mackie, E. R. R., Mckay, M. V., Barrow, A. S., & da Costa, T. P. S. (2025). Inhibitors of lysine biosynthesis enzymes as potential new herbicides. Functional Plant Biology, 52(5), FP25030-1-FP25030-13.
DOI
2023 Javorsky, A., Maddumage, J. C., Mackie, E. R. R., Soares da Costa, T. P., Humbert, P. O., & Kvansakul, M. (2023). Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 PBM. The FEBS journal, 290(4), 974-987.
DOI Scopus9 WoS9 Europe PMC9
2023 Mackie, E. R. R., Barrow, A. S., Giel, M. -C., Hulett, M. D., Gendall, A. R., Panjikar, S., & Soares da Costa, T. P. (2023). Repurposed inhibitor of bacterial dihydrodipicolinate reductase exhibits effective herbicidal activity. Communications Biology, 6(1), 1-11.
DOI Scopus3 WoS3 Europe PMC4
2022 Mackie, E. R. R., Barrow, A. S., Christoff, R. M., Abbott, B. M., Gendall, A. R., & Soares da Costa, T. P. (2022). A dual-target herbicidal inhibitor of lysine biosynthesis. eLife, 11, 1-11.
DOI Scopus8 WoS7 Europe PMC6
2022 Teakel, S., Marama, M., Aragao, D., Tsimbalyuk, S., Mackie, E. R. R., da Costa, T. P. S., . . . Cahill, M. A. (2022). Structural characterisation of a MAPR-related archaeal cytochrome b(5M) protein. FEBS Letters, 596(18), 2409-2417.
DOI Scopus3 WoS3 Europe PMC2
2021 Nonis, S. G., Haywood, J., Schmidberger, J. W., Mackie, E. R. R., Soares da Costa, T. P., Bond, C. S., & Mylne, J. S. (2021). Structural and biochemical analyses of concanavalin A circular permutation by jack bean asparaginyl endopeptidase. Plant Cell, 33(8), 2794-2811.
DOI Scopus24 WoS20 Europe PMC17
2020 Li, Z., MacKie, E. R. R., Ramkissoon, P., Mather, J. C., Wiratpruk, N., Soares Da Costa, T. P., & Barnard, P. J. (2020). Synthesis, conformational analysis and antibacterial activity of Au(I)-Ag(I) and Au(I)-Hg(II) heterobimetallic N-heterocyclic carbene complexes. Dalton Transactions, 49(36), 12820-12834.
DOI Scopus14 WoS14 Europe PMC7
2020 Hall, C. J., Mackie, E. R. R., Gendall, A. R., Perugini, M. A., & Soares da Costa, T. P. (2020). Review: amino acid biosynthesis as a target for herbicide development. Pest Management Science, 76(12), 3896-3904.
DOI Scopus25 WoS20 Europe PMC18
2020 Giel, M. C., Smedley, C. J., Mackie, E. R. R., Guo, T., Dong, J., Soares da Costa, T. P., & Moses, J. E. (2020). Metal-Free Synthesis of Functional 1-Substituted-1,2,3-Triazoles from Ethenesulfonyl Fluoride and Organic Azides. Angewandte Chemie - International Edition, 59(3), 1181-1186.
DOI Scopus77 WoS75 Europe PMC32

Year Citation
2022 Antoney, J., Kainrath, S., Ahmed, H., Kang, S. W., Mackie, E., Soares da Costa, T., . . . Janovjak, H. (2022). A F<sub>420</sub>-dependent single domain chemogenetic tool for protein de-dimerization.
DOI
2022 Mackie, E., Barrow, A., Christoff, R., Abbott, B., Gendall, A., & Soares da Costa, T. (2022). A dual-target herbicidal inhibitor of lysine biosynthesis.
DOI
2019 Giel, M. -C., Smedley, C., Mackie, E., Guo, T., Dong, J., Costa, T. S. D., & Moses, J. (2019). Metal-Free Click Synthesis of Functional 1-Substituted-1,2,3-Triazoles.
DOI
Date Project Funding Body Role Amount
2025-2028 Learning lessons from drug resistance to tackle herbicide resistance Australian Research Council Discovery Project Investigator $666,653
2025 Investigating a novel mediator of plant-to-plant communication Elizabeth MacMeikan Trust (University of Adelaide) Chief Investigator $11,210
2025 Towards a novel strategy to mitigate herbicide resistance spread  Faculty of SET EMCR Grant (University of Adelaide) Chief Investigator $10,000
2023 Engineering plants to reverse herbicide resistance in weeds Charlick Fund (University of Adelaide) Chief Investigator $11,133
2022-2025 Novel diagnostic tools to monitor and combat herbicide resistance Hermon Slade Foundation Investigator  $77,842
2019-2022 Development of herbicide cocktails with a novel mode of action for circumventing resistance mechanisms Grains Research and Development Corporation  Investigator  $107,091

Date Role Research Topic Program Degree Type Student Load Student Name
2025 Co-Supervisor Targeted Herbicide Development: Exploring Novel Modes of Action to Combat Resistance Doctor of Philosophy Doctorate Full Time Ms Lilitha Njobe
2025 Co-Supervisor Targeted Herbicide Development: Exploring Novel Modes of Action to Combat Resistance Doctor of Philosophy Doctorate Full Time Ms Lilitha Njobe

Date Role Research Topic Location Program Supervision Type Student Load Student Name
2024 - ongoing Co-Supervisor A dual-pronged approach to tackling herbicide resistance University of Adelaide - Honours Full Time Eloise Hart

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