Dr Ella Green

NHMRC Grant-Funded Researcher A

School of Biomedicine

Faculty of Health and Medical Sciences

Ella Green is a Postdoctoral researcher in the Reproductive Immunology group, under the supervision of Prof. Sarah Robertson. Ella undertakes novel research in the field of reproductive biology, with a focus on the immunology of reproduction. Her vision is to discover new knowledge on the biological roles of immune cells in pregnancy and reproduction function by applying basic molecular and cellular immunology techniques to animal models of reproductive pathologies. Ella uses several experimental strategies including animal models, cellular biology, flow cytometry, and cell isolation and culture in her work.

Her specific focus is to determine the involvement of maternal T cell plasticity in normal pregnancy, and in fertility and pregnancy complications including preterm labour (PTL), intrauterine-growth restriction (IUGR) and luteal phase deficiency (LPD). The ultimate goal of this work is to promote translation of these research findings to improve reproductive outcomes in women.

Career
Publications
Supervision
Professional Activities
Contact

Appointments

Date	Position	Institution name
2020 - 2021	NHMRC Postoctoral Researcher	Universtiy of Adelaide
2019 - 2020	Postdoctoral Research Scientist	University Medical Center Hamburg-Eppendorf (UKE)

Education

Date	Institution name	Country	Title
2015 - 2020	Universtiy of Adelaide	Australia	PhD (Medicine)
2014 - 2014	University of Adelaide	Australia	Bachelor of Science (Honours)
2011 - 2013	University of Adelaide	Australia	Bachelor of Science (Molecular Biology)

Research Interests

Early Origins of Health Fertility and Conception Immunology and Infection Pregnancy and Birth Animal Growth and Development Animal Immunology Cellular Immunology Developmental Biology Fertility Immunology Reproductive Biology

Journals

Year	Citation
2022	Robertson, S. A., Moldenhauer, L. M., Green, E. S., Care, A. S., & Hull, M. L. (2022). Immune determinants of endometrial receptivity: a biological perspective. Fertility and Sterility, 117(6), 1107-1120. DOI
2021	Schjenken, J. E., Green, E. S., Overduin, T. S., Mah, C. Y., Russell, D. L., & Robertson, S. A. (2021). Endocrine disruptor compounds-a cause of impaired immune tolerance driving inflammatory disorders of pregnancy?. Frontiers in Endocrinology, 12, 607539-1-607539-15. DOI Scopus7 WoS5 Europe PMC2
2021	Schjenken, J. E., Sharkey, D. J., Green, E. S., Chan, H. Y., Matias, R. A., Moldenhauer, L. M., & Robertson, S. A. (2021). Sperm modulate uterine immune parameters relevant to embryo implantation and reproductive success in mice. Communications Biology, 4(1), 1-14. DOI Scopus9 WoS10 Europe PMC4
2021	Foyle, K. L., Sharkey, D. J., Moldenhauer, L. M., Green, E. S., Wilson, J. J., Roccisano, C. J., . . . Robertson, S. A. (2021). Effect of Intralipid infusion on peripheral blood T cells and plasma cytokines in women undergoing assisted reproduction treatment. Clinical and Translational Immunology, 10(8), e1328-1-e1328-17. DOI Scopus2
2020	Kieffer, T. E. C., Chin, P. Y., Green, E. S., Moldenhauer, L. M., Prins, J. R., & Robertson, S. A. (2020). Prednisolone in early pregnancy inhibits regulatory T cell generation and alters fetal and placental development in mice. Molecular Human Reproduction, 26(5), 340-352. DOI Scopus6 WoS6 Europe PMC4
2020	Green, E. S., & Arck, P. C. (2020). Pathogenesis of preterm birth: bidirectional inflammation in mother and fetus. Seminars in Immunopathology, 42(4), 413-429. DOI Scopus29 WoS28 Europe PMC18
2019	Robertson, S. A., Green, E. S., Care, A. S., Moldenhauer, L. M., Prins, J. R., Hull, M. L., . . . Dekker, G. (2019). Therapeutic potential of regulatory T cells in preeclampsia-opportunities and challenges. Frontiers in Immunology, 10(MAR), 478-1-478-18. DOI Scopus34 WoS28 Europe PMC20
2019	Moldenhauer, L. M., Schjenken, J. E., Hope, C. M., Green, E. S., Zhang, B., Eldi, P., . . . Robertson, S. A. (2019). Thymus-derived regulatory T cells exhibit Foxp3 epigenetic modification and phenotype attenuation after mating in mice. Journal of Immunology, 203(3), 647-657. DOI Scopus16 WoS16 Europe PMC7
2018	Brown, H., Green, E., Tan, T., Gonzalez, M., Rumbold, A., Hull, M., . . . Thompson, J. (2018). Periconception onset diabetes is associated with embryopathy and fetal growth retardation, reproductive tract hyperglycosylation and impaired immune adaptation to pregnancy. Scientific reports, 8(1), 2114-1-2114-13. DOI Scopus17 WoS17 Europe PMC8
2018	Mihalas, B. P., Houston, B. J., Green, E. S., Enninga, E. A. L., & Calderón, E. A. R. (2018). The Primordial Journey. Molecular reproduction and development, 85(11), 809. DOI

Conference Papers

Year	Citation
2019	Kieffer, E. C., Chin, P. Y., Green, E. S., Moldenhauer, L. M., Prins, J. R., & Robertson, S. A. (2019). Prednisolone Treatment in Early Pregnancy Disrupts Maternal Immune Adaptation and Alters Pregnancy Outcomes in Mice.. In REPRODUCTIVE SCIENCES Vol. 26 (pp. 291A-292A). Paris, FRANCE: SAGE PUBLICATIONS INC.
2019	Green, E. S., Moldenhauer, L. M., McColl, S. M., & Robertson, S. A. (2019). Regulatory T Cells are a Key Agent of Progesterone Effects in Early Pregnancy.. In REPRODUCTIVE SCIENCES Vol. 26 (pp. 118A). Paris, FRANCE: SAGE PUBLICATIONS INC.
2016	Green, E., Moldenhauer, L. M., Kara, E. E., Chin, P. Y., Robker, R. L., McColl, S. R., & Robertson, S. A. (2016). Progesterone control of regulatory T cell phenotype and abundance in pregnancy - A novel role for non-classical progesterone action. In JOURNAL OF REPRODUCTIVE IMMUNOLOGY Vol. 115 (pp. 43). Erfurt, GERMANY: ELSEVIER IRELAND LTD. DOI

Conference Items

Year	Citation
2018	Robertson, S. A., Green, E. S., McColl, S. R., & Moldenhauer, L. M. (2018). Peri-Implantation Progesterone Determines Regulatory T Cell Competence to Impact Late Gestation Pregnancy Outcome in Mice.. Poster session presented at the meeting of REPRODUCTIVE SCIENCES. San Diego, CA: SAGE PUBLICATIONS INC.
2018	Green, E. S., Moldenhauer, L. M., McColl, S. R., & Robertson, S. A. (2018). Reduced progesterone signalling at implantation compromises Treg cell tolerance and impairs fetal growth and viability in later gestation. Poster session presented at the meeting of CLINICAL ENDOCRINOLOGY. Perth, AUSTRALIA: WILEY.
2016	Green, E. S., Moldenhauer, L. M., Kara, E. E., Chin, P. Y., Robker, R. L., McColl, S. R., & Robertson, S. A. (2016). Regulatory T cell abundance and phenotype in pregnancy - a novel role for progesterone potentially independent of nuclear progesterone receptor. Poster session presented at the meeting of EUROPEAN JOURNAL OF IMMUNOLOGY. Melbourne, AUSTRALIA: WILEY-BLACKWELL.

Current Higher Degree by Research Supervision (University of Adelaide)

Date	Role	Research Topic	Program	Degree Type	Student Load	Student Name
2021	Co-Supervisor	Regulatory T cell contributions to maternal immune system dysfunction in preterm birth	Doctor of Philosophy	Doctorate	Full Time	Miss Jessie Rose Walker

Committee Memberships

Date	Role	Committee	Institution	Country
2018 - 2018	Member	Local Organising Committee for the 50th Annual Meeting of the Society of Reproductive Biology	Society for Reproductive Biology	Australia
2016 - 2017	Member	Australian Society for Immunology Events committee SA/NT Branch	University of Adelaide	Australia

Review, Assessment, Editorial and Advice

Date	Title	Type	Institution	Country
2020 - 2020	Seminars in Immunopathology	Peer Review	University Medical Center, Hamburg-Eppendorf (UKE)	Germany
2020 - 2020	Molecular Reproduction and Development	Peer Review	University Medical Center, Hamburg-Eppendorf (UKE)	Germany
2017 - 2018	Molecular Human Reproduction	Peer Review	University of Adelaide	Australia

Position: NHMRC Grant-Funded Researcher A
Email: ella.green@adelaide.edu.au
Campus: North Terrace
Building: Adelaide Health and Medical Sciences, floor 6
Org Unit: Medical Sciences