Elizabeth Melville

Mrs Elizabeth Melville

Senior Technical Officer

SpecServ -Engineering and Information Technology

College of Engineering and Information Technology


Liz holds a BSc with Honours from the University of Sydney. With a research background of more than 20 years she has extensive experience in a range of laboratory techniques, specialising in tissue culture, real-time PCR, molecular analysis, RNA isolation, western blotting, gene cloning, histology and immunohistochemistry.
In her current role as a Senior Technical Officer in STEM Liz manages the PC2 and Office of Gene Technology Regulations (OGTR) certified laboratories across the Future Industries Institute at the Mawson Lakes campus. She works closely with over 60 researchers and students in the biological labs providing advice on experimental protocols to ensure compliance with the OGTR and the ASNZS 2243:3 Safety in Microbiological Laboratories guidelines. Liz manages the major tissue culture facility on campus providing inductions, training in aseptic techniques and the provision of consumables and reagents for this shared facility. She also uses her research experience to train new users in many specific pieces of equipment such as the Incucyte cell imaging system, Real time PCR, autoclaves, plate readers and spectroscopy equipment.
Liz is an administrator for Freezer Pro which is a database used extensively by the biological researchers to document samples stored in Cold storage units. She oversaw the implementation of the system throughout UniSA STEM and the Future Industries Institute and provides advanced training. Additionally, she coordinates annual biostocktakes to ensure institutional compliance to current WHS standards. Liz is also involved with FM:Interact which acts as the enterprise-wide register for Controlled Environment Devices at the University. She is an experienced user of Chemwatch and UniSAfe and is involved in the approval of risk assessments for all chemical/biological projects being conducted in the PC2/OGTR laboratories.
As part of her role Liz monitors and reviews WHS performance while implementing WHS improvements. She completes regular lab and building inspections, the investigation of near misses and incidents, chemical audits, as well as the implementation of corrective actions. She is dedicated to providing a safe and healthy workplace for all UniSA STEM staff and students.

Year Citation
2021 Yamada, M., Melville, E., Cowin, A. J., Prow, T. W., & Kopecki, Z. (2021). Microbiopsy-based minimally invasive skin sampling for molecular analysis is acceptable to Epidermolysis Bullosa Simplex patients where conventional diagnostic biopsy was refused. Skin Research and Technology, 27(3), 461-463.
DOI Scopus3 WoS3 Europe PMC3
2020 Rajeev, G., Melville, E., Cowin, A. J., Prieto Simon, B., & Voelcker, N. H. (2020). Porous alumina membrane-based electrochemical biosensor for protein biomarker detection in chronic wounds. Frontiers in Chemistry, 8(155), 1-11.
DOI Scopus25 WoS20 Europe PMC10
2018 Kopecki, Z., Stevens, N. E., Yang, G. N., Melville, E., & Cowin, A. J. (2018). Recombinant leucine-rich repeat flightless-interacting protein-1 improves healing of acute wounds through its effects on proliferation inflammation and collagen deposition. International Journal of Molecular Sciences, 19(7), 2014-1-2014-12.
DOI Scopus12 WoS12 Europe PMC9
2017 Haidari, H., Zhang, Q., Melville, E., Kopecki, Z., Song, Y., Cowin, A., & Garg, S. (2017). Development of topical delivery systems for flightless neutralizing antibody. Journal of Pharmaceutical Sciences, 106(7), 1795-1804.
DOI Scopus14 WoS16 Europe PMC10
2017 Turner, C. T., Mcinnes, S. J. P., Melville, E., Cowin, A., & Voelcker, N. H. (2017). Delivery of flightless I neutralizing antibody from porous silicon nanoparticles improves wound healing in diabetic mice. Advanced healthcare materials, 6(2, article no. 1600707), 1-13.
DOI Scopus41 WoS40 Europe PMC29
2017 Turner, C. T., McInnes, S. J. P., Melville, E., Cowin, A. J., & Voelcker, N. H. (2017). Wound healing: delivery of flightless I neutralizing antibody from porous silicon nanoparticles improves wound healing in diabetic mice (Adv. Healthcare Mater. 2/2017). Advanced healthcare materials, 6(2), 1.
DOI
2016 Cameron, A., Turner, C., Adams, D., Jackson, J., Melville, E., Arkell, R., . . . Cowin, A. (2016). Flightless I is a key regulator of the fibroproliferative process in hypertrophic scarring and a target for a novel antiscarring therapy. British Journal of Dermatology, 174(4), 786-794.
DOI Scopus22 WoS23 Europe PMC18
2016 Turner, C. T., Hasanzadeh, K. M., Melville, E., Delalat, B., Harding, F., Makila, E., . . . Voelcker, N. H. (2016). Delivery of flightless I siRNA from porous silicon nanoparticles improves wound healing in mice. ACS biomaterials science and engineering, 2(12), 2339-2346.
DOI Scopus39 WoS36 Europe PMC22
2016 Turner, C. T., McInnes, S. J. P., Melville, E., Voelcker, N. H., & Cowin, A. J. (2016). Delivery of flightless I neutralizing antibody from porous silicon nanoparticles improves healing in diabetic mice. Wound repair and regeneration, 24(6), 17-18.
2015 Kopecki, Z., Yang, G., Jackson, J., Melville, E., Caley, M., Murrell, D., . . . Cowin, A. (2015). Cytoskeletal protein flightless I inhibits apoptosis, enhances tumor cell invasion and promotes cutaneous squamous cell carcinoma progression. Oncotarget, 6(34), 36426-36440.
DOI Scopus24 WoS23 Europe PMC22
2014 Kopecki, Z., Yang, G., Arkell, R., Jackson, J., Melville, E., Iwata, H., . . . Cowin, A. (2014). Flightless I over-expression impairs skin barrier development, function and recovery following skin blistering. Journal of Pathology, 232(5), 541-552.
DOI Scopus24 WoS27 Europe PMC21
2014 Ruzehaji, N., Kopecki, Z., Melville, E., Appleby, S., Bonder, C., Arkell, R., . . . Cowin, A. (2014). Attenuation of flightless I improves wound healing and enhances angiogenesis in a murine model of type 1 diabetes. Diabetologia, 57(2), 402-412.
DOI Scopus30 WoS28 Europe PMC25
2014 Kopecki, Z., Yang, G., Jackson, J., Melville, E., Martin, V., Caley, M., . . . Cowin, A. J. (2014). Cytoskeletal protein Flii is elevated in human cSCCs and overexpression of Flii in mice leads to higher incidence and severity of tumour formation. Journal of investigative dermatology, 134(162), 28.
2014 Kopecki, Z., Yang, G., Jackson, J., Melville, E., Martin, V., Matthew, C., . . . Cowin, A. (2014). Treatment of SCC with flightless neutralizing antibody blocks cell invasion and reduces tumor growth in mice. Wound repair and regeneration, 22(2), 49.
2013 Ruzehaji, N., Mills, S., Melville, E., Arkell, R., Fitridge, R., & Cowin, A. (2013). The influence of Flightless I on toll-like-receptor-mediated inflammation in a murine model of diabetic wound healing. BioMed Research International, 2013(389792), 389792-1-389792-9.
DOI Scopus18 WoS17 Europe PMC17
2013 Krismastuti, F. S. H., Pace, S., Melville, E., Cowin, A. J., Dargaville, T. R., & Voelcker, N. (2013). Matrix metalloproteinase biosensor based on a porous silicon reflector. Australian journal of chemistry, 66(11), 1428-1434.
DOI Scopus12 WoS11
2010 Brown, C., Sadlon, T., Gargett, T., Melville, E., Zhang, R., Drabsch, Y., . . . Barry, S. (2010). Robust, reversible gene knockdown using a single lentiviral short hairpin RNA vector. Human Gene Therapy, 21(8), 1005-1017.
DOI Scopus27 WoS28 Europe PMC24
2010 Sadlon, T., Wilkinson, B., Pederson, S., Brown, C., Bresatz, S., Gargett, T., . . . Barry, S. (2010). Genome-wide identification of human FOXP3 target genes in natural regulatory T cells. Journal of Immunology, 185(2), 1071-1081.
DOI Scopus124 WoS122 Europe PMC112
2007 Karageorgos, L., Brooks, D., Pollard, A., Melville, E., Hein, L., Clements, P., . . . Hopwood, J. (2007). Mutational analysis of 105 mucopolysaccharidosis type VI patients. Human Mutation, 28(9), 897-903.
DOI Scopus114 WoS97 Europe PMC83
2007 Karageorgos, L., Brooks, D., Harmatz, P., Ketteridge, D., Pollard, A., Melville, E., . . . Hopwood, J. (2007). Mutational analysis of mucopolysaccharidosis type VI patients undergoing a phase II trial of enzyme replacement therapy. Molecular Genetics and Metabolism, 90(2), 164-170.
DOI Scopus18 WoS17 Europe PMC15
2003 Nelson, K., Melville, E., Meikle, P., & Anson, D. (2003). Immortalisation of a mucopolysaccharidosis type IIIC fibroblast cell line via expression of SV40 T antigen. Cell Biology International, 27(7), 567-570.
DOI Scopus4 Europe PMC1

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