Danny Wilson

Dr Danny Wilson


School of Biological Sciences

Faculty of Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Single cell parasites such as malaria and Toxoplasma remain leading causes of disease in children and during pregnancy, with Australia and our nearest neighbours continuing to be impacted. Malaria alone causes >400,000 deaths per year, with children under five and pregnant women most at risk. The burden of Malaria falls on developing tropical and sub-tropical countries throughout the world, with the health and prosperity of Australia's nearest neighbours and major trading partners still heavily affected by these mosquito borne parasites. Up to a third of the worlds population is infected with food and water borne Toxoplasma parasites that can cause severe disease during pregnancy and for immunocompromised people, with the long-term impacts of infection not fully understood.
Our research applies multi-disciplinary approaches to better understand the unique biology of these parasites. We use this information to prioritise and develop vaccines that protect against infection and for the identification of new drug treatment strategies to cure people infected with these widespread disease causing parasites.

Half of the world’s population is at risk of infection with mosquito-borne malaria parasites of the genus Plasmodium. These complex eukaryotic parasites that live inside human cells cause widespread sickness and death throughout tropical and sub-tropical regions of the world including countries neighbouring Australia. The majority of the >400,000 malaria related deaths that occur each year are caused by the parasite Plasmodium falciparum in children under 5 years in Africa, Asia and South America.

Unfortunately, resistance has developed to our most effective anti-malarial drugs, resulting in poorer treatment outcomes for clinical cases of this deadly parasite. There is an urgent need to identify novel drugs to partner with current first-line treatments to fill this looming treatment gap. In addition, development of an effective vaccine would reduce the burden of disease and greatly facilitate efforts to eradicate malaria. Unfortunately, a highly effective vaccine to protect against malaria has not been developed to date and efforts to identify the best vaccine targets are ongoing.

My laboratory seeks to identify and characterise novel parasite proteins for their suitability as both drug and vaccine targets. We focus on invasion of the human red blood cell by the small invasive merozoite stage of the parasite lifecycle as a therapeutic target. By developing therapeutics (drugs and vaccines) that inhibit merozoite invasion of the red blood cell we can instantly disrupt the lifecycle of the parasite in the stage that causes all the symptoms of the disease. We apply a breakthrough P. falciparum merozoite purification method (PNAS, 2010) that is superior to alternatives for studying malaria parasite invasion biology, opening up new opportunities to study this previously intractable lifecycle stage (Figure 1).

Antimalarials that inhibit invasion

By applying state of the art methods, we aim to develop invasion inhibitory antimalarials as viable drugs in a climate of increasing resistance to frontline treatments. Using a highly reproducible flow cytometry approach (Antimicrobial Agents & Chemotherapy, 2013; Figure 2 A & B), we have screened traditional antimalarial therapies, protease inhibitors, kinase inhibitors, a range of antibiotics and identified several compounds and there analogues that rapidly inhibit merozoite invasion (BMC Biology, 2015). To understand how drug-like compounds target the essential process of merozoite invasion, we apply mutation analysis of gene targets, phenotypic screens of related Apicomplexan parasites, modifications and screens of analogues, fluorescence microscopy localisation and proteomic identification of drug binding targets. Importantly, many of the invasion inhibitory compounds identified in our research also kill at other stages of the parasites complex lifecycle, increasing there utility as broad acting antimalarials. Development of these invasion inhibitory compounds and identification of the mechanisms by which they inhibit invasion is the subject of ongoing research in the laboratory.

Functional characterisation of poorly defined merozoite vaccine targets

The function of nearly 50% of the genes in P. falciparum parasites is poorly described or not known altogether. Malaria proteins involved in invasion are no exception with a large number of potential vaccine targets having no known function. We apply gene-editing techniques to examine the potential role of some of these proteins in invasion and parasite growth. Using fluorescence microscopy, flow cytometry, genetic manipulation and proteomic techniques, we are characterising the localisation, interactions and functions of merozoite antigens with no known function to test their suitability as therapeutic targets.

Postgraduate and undergraduate opportunities

Honours, summer-student, masters and PhD projects are available to explore the biology of the malaria parasite and to develop new therapies against this deadly infectious organism. We are a small, supportive, research team that is applying new technologies to discover new ways of ending the burden of malaria disease. If you would like to find out more about our current research opportunities and whether our research is right for you, please contact Dr. Danny Wilson (danny.wilson@adelaide.edu.au). 

  • Appointments

    Date Position Institution name
    2017 - 2019 DVCR 3 Year Mid-career Beacon Fellowship University of Adelaide, Adelaide
    2015 Laboratory Head University of Adelaide
    2014 Burnet Institute Research Fellow (Honorary) Burnet Institute, Melbourne
    2014 - 2015 Senior Research Fellow (with Prof. James Paton) University of Adelaide
    2012 - 2015 Peter Doherty, Early Career Fellowship National Health and Medical Research Council, Canberra
    2011 - 2013 Senior Research Fellow (with Prof. Alan Cowman) Walter and Eliza Hall Institute of Medical Research, Melbourne
    2009 - 2011 Research Officer (with Prof. James Beeson) Walter and Eliza Hall Institute of Medical Research, Melbourne
  • Awards and Achievements

    Date Type Title Institution Name Country Amount
    2020 Award Faculty of Sciences Mid-Career Researcher Excellence Award The University of Adelaide Australia
    2020 Fellowship Mid-career Fellowship (2020-2022) The Hospital Research Foundation Australia
    2019 Award Young Tall Poppy SA Award AIPS Australia
    2017 Fellowship DVCR, Beacon Fellowship (2017-2019) The University of Adelaide Australia
    2015 Award Faculty of Sciences Early Career Researcher Travel Award The University of Adelaide Australia
    2013 Award CASS Foundation travel Grant CASS Foundation Australia
    2012 Award Post Doctoral Association travel award Walter & Eliza Hall Institute Australia
    2012 Fellowship Peter Doherty Early Career Fellowship NHMRC Australia
  • Education

    Date Institution name Country Title
    2004 - 2009 University of Melbourne, Melbourne Australia PhD
  • Research Interests

  • Journals

    Year Citation
    2021 Liang, X. L., Ji, M. M., Chen, L., Liao, Y., Kong, X. Q., Xu, X. Q., . . . Wilson, D. W. (2021). Traditional Chinese herbal medicine Astragalus Radix and its effects on intestinal absorption of aconite alkaloids in rats. Chinese Herbal Medicines, 13(2), 235-242.
    2021 Ferreira, J. L., Heincke, D., Wichers, J. S., Liffner, B., Wilson, D. W., & Gilberger, T. W. (2021). The Dynamic Roles of the Inner Membrane Complex in the Multiple Stages of the Malaria Parasite. Frontiers in Cellular and Infection Microbiology, 10, 1-12.
    DOI Scopus3 WoS3 Europe PMC2
    2021 Nguyen, W., Dans, M. G., Ngo, A., Gancheva, M. R., Romeo, O., Duffy, S., . . . Sleebs, B. E. (2021). Structure activity refinement of phenylsulfonyl piperazines as antimalarials that block erythrocytic invasion. European Journal of Medicinal Chemistry, 214, 113253-1-113253-27.
    DOI Scopus1
    2021 Trott, D. J., Turnidge, J., Kovac, J. H., Simjee, S., Wilson, D., & Watts, J. (2021). Comparative macrolide use in humans and animals: Should macrolides be moved off the World Health Organisation's critically important antimicrobial list?. Journal of Antimicrobial Chemotherapy, 76(8), 1955-1961.
    2021 Liffner, B., Balbin, J. M., Wichers, J. S., Gilberger, T. W., & Wilson, D. W. (2021). The Ins and Outs of Plasmodium Rhoptries, Focusing on the Cytosolic Side. Trends in Parasitology, 37(7), 638-650.
    2021 Bailey, B. L., Nguyen, W., Ngo, A., Goodman, C. D., Gancheva, M. R., Favuzza, P., . . . Sleebs, B. E. (2021). Optimisation of 2-(N-phenyl carboxamide) triazolopyrimidine antimalarials with moderate to slow acting erythrocytic stage activity. Bioorganic Chemistry, 115, 105244.
    2020 Burda, P. -C., Crosskey, T., Lauk, K., Zuborg, A., Sohnchen, C., Liffner, B. S., . . . Gilberger, T. (2020). Structure-Based Identification and Functional Characterization of a Lipocalin in the Malaria Parasite Plasmodium falciparum. Cell Reports, 31(12), 1-7.
    DOI Scopus3 WoS3
    2020 Adderley, J. D., John von Freyend, S., Jackson, S. A., Bird, M. J., Burns, A. L., Anar, B., . . . Doerig, C. (2020). Analysis of erythrocyte signalling pathways during Plasmodium falciparum infection identifies targets for host-directed antimalarial intervention. Nature Communications, 11(1), 4015.
    DOI Scopus5 WoS4 Europe PMC2
    2020 Burns, A. L., Sleebs, B. E., Siddiqui, G., De Paoli, A. E., Anderson, D., Liffner, B., . . . Wilson, D. W. (2020). Retargeting azithromycin analogues to have dual-modality antimalarial activity. BMC Biology, 18(1), 133-1-133-23.
    DOI Scopus2
    2020 Sleebs, B. E., Jarman, K. E., Frolich, S., Wong, W., Healer, J., Dai, W., . . . Cowman, A. F. (2020). Development and application of a high-throughput screening assay for identification of small molecule inhibitors of the P. falciparum reticulocyte binding-like homologue 5 protein. International Journal for Parasitology: Drugs and Drug Resistance, 14, 188-200.
    2020 Geiger, M., Brown, C., Wichers, J. S., Strauss, J., Lill, A., Thuenauer, R., . . . Gilberger, T. W. (2020). Structural insights into PfARO and characterization of its interaction with PfAIP. Journal of Molecular Biology, 432(4), 878-896.
    DOI Scopus4 WoS4
    2020 Liffner, B., Frolich, S., Heinemann, G. K., Liu, B., Ralph, S. A., Dixon, M. W. A., . . . Wilson, D. W. (2020). PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes. Nature Communications, 11(1), 1411-1-1411-14.
    DOI Scopus6 WoS6 Europe PMC2
    2020 Dans, M., Weiss, G., Wilson, D., Sleebs, B., Crabb, B., de Koning-Ward, T., & Gilson, P. (2020). Screening the Medicines for Malaria Venture Pathogen Box for invasion and egress inhibitors of the blood stage of Plasmodium falciparum reveals several inhibitory compounds. International Journal for Parasitology, 50(3), 235-252.
    DOI Scopus4 WoS4 Europe PMC2
    2019 Pehere, A. D., Nguyen, S., Garlick, S. K., Wilson, D. W., Hudson, I., Sykes, M. J., . . . Abell, A. D. (2019). Tripeptide analogues of MG132 as protease inhibitors. Bioorganic and Medicinal Chemistry, 27(2), 436-441.
    DOI Scopus2 WoS2
    2019 Burns, A. L., Dans, M. G., Balbin, J. M., F de Koning-Ward, T., Gilson, P. R., Beeson, J. G., . . . Wilson, D. W. (2019). Targeting malaria parasite invasion of red blood cells as an antimalarial strategy. FEMS Microbiology Reviews, 43(3), 223-238.
    DOI Scopus21 WoS20 Europe PMC6
    2019 Reiling, L., Boyle, M. J., White, M. T., Wilson, D. W., Feng, G., Weaver, R., . . . Beeson, J. G. (2019). Targets of complement-fixing antibodies in protective immunity against malaria in children. Nature Communications, 10(1), 610-1-610-13.
    DOI Scopus27 WoS27 Europe PMC20
    2019 Wichers, J. S., Scholz, J. A. M., Strauss, J., Witt, S., Lill, A., Ehnold, L. I., . . . Bachmann, A. (2019). Dissecting the gene expression, localization, membrane topology, and function of the plasmodium falciparum STEVOR protein family. mBio, 10(4), e01500-1-e01500-19.
    DOI Scopus6 WoS6 Europe PMC3
    2019 Liffner, B., Frölich, S., Heinemann, G., Liu, B., Dixon, M., Gilberger, T. -W., & Wilson, D. (2019). PfCERLI1, a conserved rhoptry associated protein essential for invasion byPlasmodium falciparummerozoites.
    2019 Oyong, D., Wilson, D., Barber, B., William, T., Jiang, J., Galinski, M., . . . Boyle, M. (2019). Induction and kinetics of complement-fixing antibodies against Plasmodium vivax merozoite surface protein 3α and relationship with immunoglobulin G subclasses and immunoglobulin M. The Journal of Infectious Diseases, 220(12), 1950-1961.
    DOI Scopus6 WoS5 Europe PMC5
    2018 Nguyen, N., Wilson, D., Nagalingam, G., Triccas, J., Schneider, E., Li, J., . . . Baell, J. (2018). Broad activity of diphenyleneiodonium analogues against Mycobacterium tuberculosis, malaria parasites and bacterial pathogens. European Journal of Medicinal Chemistry, 148, 507-518.
    DOI Scopus6 WoS6 Europe PMC2
    2018 Lyth, O., Vizcay-Barrena, G., Wright, K., Haase, S., Mohring, F., Najer, A., . . . Baum, J. (2018). Cellular dissection of malaria parasite invasion of human erythrocytes using viable Plasmodium knowlesi merozoites. Scientific Reports, 8(1), 10165-1-10165-11.
    DOI Scopus11 WoS10 Europe PMC10
    2017 Hill, D., Schofield, L., & Wilson, D. (2017). IgG opsonization of merozoites: multiple immune mechanisms for malaria vaccine development. International Journal for Parasitology, 47(10-11), 585-595.
    DOI Scopus8 WoS8 Europe PMC5
    2016 Volz, J., Yap, A., Sisquella, X., Thompson, J., Lim, N., Whitehead, L., . . . Cowman, A. (2016). Essential role of the PfRh5/PfRipr/CyRPA complex during plasmodium falciparum invasion of erythrocytes. Cell Host and Microbe, 20(1), 60-71.
    DOI Scopus87 WoS86 Europe PMC76
    2016 Hill, D., Wilson, D., Sampaio, N., Eriksson, E., Ryg-Cornejo, V., Abby Harrison, G., . . . Schofielda, L. (2016). Merozoite antigens of plasmodium falciparum elicit strain-transcending opsonizing immunity. Infection and Immunity, 84(8), 2175-2184.
    DOI Scopus27 WoS26 Europe PMC21
    2016 Drew, D., Wilson, D., Elliott, S., Cross, N., Terheggen, U., Hodder, A., . . . Beeson, J. (2016). A novel approach to identifying patterns of human invasion-inhibitory antibodies guides the design of malaria vaccines incorporating polymorphic antigens. BMC Medicine, 14(1), 1-14.
    DOI Scopus13 WoS13 Europe PMC10
    2015 Wilson, D., Goodman, C., Sleebs, B., Weiss, G., de Jong, N., Angrisano, F., . . . Beeson, J. (2015). Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum. BMC Biology, 13(1), 52-1-52-19.
    DOI Scopus44 WoS42 Europe PMC30
    2015 Josling, G., Petter, M., Oehring, S., Gupta, A., Dietz, O., Wilson, D., . . . Duffy, M. (2015). A Plasmodium falciparum bromodomain protein regulates invasion gene expression. Cell Host and Microbe, 17(6), 741-751.
    DOI Scopus61 WoS63 Europe PMC46
    2014 Yap, A., Azevedo, M. F., Gilson, P. R., Weiss, G. E., O'Neill, M. T., Wilson, D. W., . . . Cowman, A. F. (2014). Conditional expression of apical membrane antigen 1 in Plasmodium falciparum shows it is required for erythrocyte invasion by merozoites. Cellular Microbiology, 16(5), 642-656.
    DOI Scopus67 WoS63 Europe PMC54
    2013 Boyle, M., Wilson, D., & Beeson, J. (2013). New approaches to studying Plasmodium falciparum merozoite invasion and insights into invasion biology. International Journal for Parasitology, 43(1), 1-10.
    DOI Scopus29 WoS28 Europe PMC21
    2013 Persson, K., Fowkes, F., McCallum, F., Gicheru, N., Reiling, L., Richards, J., . . . Beeson, J. (2013). Erythrocyte-binding antigens of Plasmodium falciparum are targets of human inhibitory antibodies and function to evade naturally acquired immunity. Journal of Immunology, 191(2), 785-794.
    DOI Scopus47 WoS45 Europe PMC39
    2013 Healer, J., Thompson, J., Riglar, D., Wilson, D., Chiu, Y., Miura, K., . . . Cowman, A. (2013). Vaccination with conserved regions of erythrocyte-binding antigens induces neutralizing antibodies against multiple strains of Plasmodium falciparum. PLoS One, 8(9), e72504-1-e72504-12.
    DOI Scopus38 WoS35 Europe PMC29
    2013 Regev-Rudzki, N., Wilson, D., Carvalho, T., Sisquella, X., Coleman, B., Rug, M., . . . Cowman, A. (2013). Cell-cell communication between malaria-infected red blood cells via exosome-like vesicles. Cell, 153(5), 1120-1133.
    DOI Scopus331 WoS317 Europe PMC260
    2013 Wilson, D., Langer, C., Goodman, C., McFadden, G., & Beeson, J. (2013). Defining the timing of action of antimalarial drugs against Plasmodium falciparum. Antimicrobial Agents and Chemotherapy, 57(3), 1455-1467.
    DOI Scopus88 WoS84 Europe PMC59
    2012 Drew, D., Hodder, A., Wilson, D., Foley, M., Mueller, I., Siba, P., . . . Beeson, J. (2012). Defining the antigenic diversity of Plasmodium falciparum Apical Membrane Antigen 1 and the requirements for a multi-allele vaccine against malaria. PLoS One, 7(12), e51023-1-e51023-11.
    DOI Scopus58 WoS57 Europe PMC49
    2012 Hill, D., Eriksson, E., Carmagnac, A., Wilson, D., Cowman, A., Hansen, D., & Schofield, L. (2012). Efficient measurement of opsonising antibodies to plasmodium falciparum merozoites. PLoS One, 7(12), e15692-1-e15692-10.
    DOI Scopus25 WoS24 Europe PMC21
    2012 Marapana, D., Wilson, D., Zuccala, E., Dekiwadia, C., Beeson, J., Ralph, S., & Baum, J. (2012). Malaria parasite signal peptide peptidase is an ER-resident protease required for growth but not for invasion. Traffic, 13(11), 1457-1465.
    DOI Scopus23 WoS20 Europe PMC18
    2012 Reiling, L., Richards, J., Fowkes, F., Wilson, D., Chokejindachai, W., Barry, A., . . . Beeson, J. (2012). The Plasmodium falciparum erythrocyte invasion ligand Pfrh4 as a target of functional and protective human antibodies against malaria. PLoS One, 7(9), e45253-1-e45253-12.
    DOI Scopus45 WoS41 Europe PMC38
    2012 Taechalertpaisarn, T., Crosnier, C., Bartholdson, S., Hodder, A., Thompson, J., Bustamante, L., . . . Crabb, B. (2012). Biochemical and functional analysis of two plasmodium falciparum blood-stage 6-cys proteins: P12 and P41. PLoS One, 7(7), e41937-1-e41937-15.
    DOI Scopus32 WoS32 Europe PMC27
    2011 Arumugam, T., Takeo, S., Yamasaki, T., Thonkukiatkul, A., Miura, K., Otsuki, H., . . . Tsuboi, T. (2011). Discovery of GAMA, a Plasmodium falciparum merozoite micronemal protein, as a novel blood-stage vaccine candidate antigen. Infection and Immunity, 79(11), 4523-4532.
    DOI Scopus49 WoS49 Europe PMC45
    2011 Lopaticki, S., Maier, A., Thompson, J., Wilson, D., Tham, W., Triglia, T., . . . Cowman, A. (2011). Reticulocyte and erythrocyte binding-like proteins function cooperatively in invasion of human erythrocytes by malaria parasites. Infection and Immunity, 79(3), 1107-1117.
    DOI Scopus100 WoS96 Europe PMC86
    2011 Quelhas, D., Jimenez, A., Quinto, L., Serra-Casas, E., Mayor, A., Cistero, P., . . . Dobano, C. (2011). IgG against Plasmodium falciparum variant surface antigens and growth inhibitory antibodies in Mozambican children receiving intermittent preventive treatment with sulfadoxine-pyrimethamine. Immunobiology, 216(7), 793-802.
    DOI Scopus8 WoS8 Europe PMC5
    2011 Wilson, D., Fowkes, F., Gilson, P., Elliott, S., Tavul, L., Michon, P., . . . Beeson, J. (2011). Quantifying the importance of MSP1-19 as a target of growth-inhibitory and protective antibodies against Plasmodium falciparum in humans. PLoS One, 6(11), e27705-1-e27705-14.
    DOI Scopus42 WoS28 Europe PMC37
    2011 Riglar, D., Richard, D., Wilson, D., Boyle, M., Dekiwadia, C., Turnbull, L., . . . Baum, J. (2011). Super-resolution dissection of coordinated events during malaria parasite invasion of the human erythrocyte. Cell Host & Microbe, 9(1), 9-20.
    DOI Scopus230 WoS226 Europe PMC196
    2010 Wilson, D., Crabb, B., & Beeson, J. (2010). Development of fluorescent Plasmodium falciparum for in vitro growth inhibition assays. Malaria Journal, 9(1), 1-12.
    DOI Scopus65 WoS67 Europe PMC56
    2010 Boyle, M., Wilson, D., Richards, J., Riglar, D., Tetteh, K., Conway, D., . . . Beeson, J. (2010). Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development. Proceedings of the National Academy of Sciences of the United States of America, 107(32), 14378-14383.
    DOI Scopus188 WoS186 Europe PMC156
    2010 Tham, W., Wilson, D., Lopaticki, S., Schmidt, C., Tetteh-Quarcoo, P., Barlow, P., . . . Cowman, A. (2010). Complement receptor 1 is the host erythrocyte receptor for Plasmodium falciparum PfRh4 invasion ligand. Proceedings of the National Academy of Sciences of the United States of America, 107(40), 17327-17332.
    DOI Scopus148 WoS149 Europe PMC126
    2010 Ataide, R., Hasang, W., Wilson, D., Beeson, J., Mwapasa, V., Molyneux, M., . . . Rogerson, S. (2010). Using an improved phagocytosis assay to evaluate the effect of HIV on specific antibodies to pregnancy-associated malaria. PLoS One, 5(5), e10807-1-e10807-10.
    DOI Scopus42 WoS42 Europe PMC41
    2009 Tham, W., Wilson, D., Reiling, L., Chen, L., Beeson, J., & Cowman, A. (2009). Antibodies to reticulocyte binding protein-like homologue 4 inhibit invasion of Plasmodium falciparum into human erythrocytes. Infection and Immunity, 77(6), 2427-2435.
    DOI Scopus54 WoS51 Europe PMC46
    2008 Dent, A., Bergmann-Leitner, E., Wilson, D., Tisch, D., Kimmel, R., Vulule, J., . . . Kazura, J. (2008). Antibody-mediated growth inhibition of Plasmodium falciparum: Relationship to age and protection from parasitemia in Kenyan children and adults. PLoS One, 3(10), e3557-1-e3557-10.
    DOI Scopus60 WoS58 Europe PMC52
    2006 Auliff, A., Wilson, D. W., Russell, B., Qi, G., Chen, N., Le, N. A., . . . Cheng, Q. (2006). Amino acid mutations in Plasmodium vivax DHFR and DHPS from several geographical regions and susceptibility to antifolate drugs. American Journal of Tropical Medicine and Hygiene, 75(4), 617-621.
    DOI Scopus75 WoS72 Europe PMC55
    2005 Bell, D., Wilson, D., & Martin, L. (2005). False-positive results of a Plasmodium falciparum histidine-rich protein 2-detecting malaria rapid diagnostic test due to high sensitivity in a community with fluctuating low parasite density. American Journal of Tropical Medicine and Hygiene, 73(1), 199-203.
    DOI Scopus117 WoS116 Europe PMC104
    2005 Elliott, S. R., Duffy, M. F., Byrne, T. J., Beeson, J. G., Mann, E. J., Wilson, D. W., . . . Brown, G. V. (2005). Cross-reactive surface epitopes on chondroitin sulfate A-adherent Plasmodium falciparum-infected erythrocytes are associated with transcription of var2csa. Infection and Immunity, 73(5), 2848-2856.
    DOI Scopus40 WoS42 Europe PMC31
    2005 Duffy, M. F., Byrne, T. J., Elliott, S. R., Wilson, D. W., Rogerson, S. J., Beeson, J. G., . . . Brown, G. V. (2005). Broad analysis reveals a consistent pattern of var gene transcription in Plasmodium falciparum repeatedly selected for a defined adhesion phenotype. Molecular Microbiology, 56(3), 774-788.
    DOI Scopus75 WoS75 Europe PMC60
    2005 Chen, N., Wilson, D. W., Pasay, C., Bell, D., Martin, L. B., Kyle, D., & Cheng, Q. (2005). Origin and dissemination of chloroquine-resistant Plasmodium falciparum with mutant pfcrt alleles in the Philippines. Antimicrobial Agents and Chemotherapy, 49(5), 2102-2105.
    DOI Scopus40 WoS35 Europe PMC31
    2003 Fischer, K., Chavchich, M., Huestis, R., Wilson, D., Kemp, D., & Saul, A. (2003). Ten families of variant genes encoded in subtelomeric regions of multiple chromosomes of Plasmodium chabaudi, a malaria species that undergoes antigenic variation in the laboratory mouse. Molecular Microbiology, 48(5), 1209-1223.
    DOI Scopus28 WoS29 Europe PMC27
    2003 Holt, D. C., Fischer, K., Allen, G. E., Wilson, D., Wilson, P., Slade, R., . . . Kemp, D. J. (2003). Mechanisms for a Novel Immune Evasion Strategy in the Scabies Mite Sarcoptes Scabiei: A Multigene Family of Inactivated Serine Proteases. Journal of Investigative Dermatology, 121(6), 1419-1424.
    DOI Scopus69 WoS68 Europe PMC51
    2002 Pombo, D. J., Lawrence, G., Hirunpetcharat, C., Rzepczyk, C., Bryden, M., Cloonan, N., . . . Good, M. F. (2002). Immunity to malaria after administration of ultra-low doses of red cells infected with Plasmodium falciparum. Lancet, 360(9333), 610-617.
    DOI Scopus329 WoS323 Europe PMC249
    2001 Wilson, D., Blanche, K., & Gibb, K. (2001). Phytoplasmas and disease symptoms of crops and weeds in the semi-arid tropics of the Northern Territory, Australia. Australasian Plant Pathology, 30(2), 159-163.
    DOI Scopus27 WoS24
    2001 Holt, D., Fischer, K., Tchavtchitch, M., Wilson, D., Hauquitz, N., Hawthorne, P., . . . Kemp, D. (2001). Clags in Plasmodium falciparum and other species of Plasmodium. Molecular and Biochemical Parasitology, 118(2), 259-263.
    DOI Scopus9 WoS9 Europe PMC6
  • Conference Papers

    Year Citation

2020 - NHMRC Ideas Grant: APP2003712. CIA Dr. Danny Wilson. 

2020 - ARC LIEF (LE210100155). Advancing 4D fluorescence microscopy within Australia. CID and Management Team: Dr. Danny Wilson

2019 - Hospital Research Foundation, 3-Year Mid-career Fellowship. CIA: Dr. Danny Wilson

2019 - South Australian Sheep Industry Fund, Project Grant. CIB: Dr Danny Wilson

2019 - DAAD/Universities Australia-Germany Joint Research Co-operation Scheme (2020-2021). Lead-CI: Dr. Danny Wilson.

2017 - NHMRC Project Grant: APP1143974. CIA Dr. Danny Wilson. 

2017 - The University of Adelaide, Cross-Faculty Equipment Call. Oxford Nano-imager NIM 4 Microscope System. Lead CI: Dr. Danny Wilson

2017 - Channel 7 Children's Research Foundation Project GrantCIA: Dr. Danny Wilson

2017 - DAAD/Universities Australia-Germany Joint Research Co-operation Scheme (2018-2019). Lead-CI: Dr. Danny Wilson.

2016 - The University of Adelaide, DVCR, 3-Year Beacon Fellowship. CIA: Dr. Danny Wilson

2016 - The University of Adelaide, DVCR, Research Infrastructure Scheme. Advanced confocal microscope. CIA: Dr. Danny Wilson

2016 - The University of Adelaide, DVCR, Interdisciplinary Research Fund. Imaris microscopy analysis software. CIA: Dr. Danny Wilson

2015 - The University of Adelaide, DVCR, Interdisciplinary Research Fund. Metalloproteomics HPLC. CID: Dr. Danny Wilson

2013 - NHMRC Project Grant: APP1057960. CIC Dr. Danny Wilson. 

2011- NHMRC Peter Doherty Early Career Fellowship APP1035715. CIA Dr. Danny Wilson. 

2004- NHMRC Dora Lush PhD Scholarship 2004-2008: APP305553. CIA: Dr. Danny Wilson. 

  • 3rd Year: Infection and Immunity A, 2 lectures, Semester 1.
  • 2nd Year: Biomedical Science, 2 lectures, Semester 2.
  • 2nd Year: BSc Advance Mentor, Semester 1.
  • 1st Year: SGDE for human perspectives, Semester 2.
  • Current Higher Degree by Research Supervision (University of Adelaide)

    Date Role Research Topic Program Degree Type Student Load Student Name
    2021 Co-Supervisor Development of methods to control toxoplasmosis and associated apicomplexan parasites in livestock Doctor of Philosophy Doctorate Full Time Mr Quinn Phillip Mackie
    2021 Principal Supervisor Insights into the Biological Constraints on Malaria Red Blood Cell Invasion and the Implications for Vaccine Development Doctor of Philosophy Doctorate Full Time Miss Jill Chmielewski
    2019 Principal Supervisor Functional characterisation of a putative Plasmodium falciparum invasion ligand and its homologues Doctor of Philosophy Doctorate Full Time Mr Juan Miguel Balbin
    2018 Principal Supervisor Characterisation of the Function and Vaccine Potential of Surface Exposed Antigens Required for Malaria Parasite Invasion of Human Host Cells Doctor of Philosophy Doctorate Full Time Ms Isabelle Grace Henshall
  • Past Higher Degree by Research Supervision (University of Adelaide)

    Date Role Research Topic Program Degree Type Student Load Student Name
    2017 - 2020 Principal Supervisor Functional Characterisation Of Novel Plasmodium falciparum Proteins And Their Role In Erythrocyte Invasion. Doctor of Philosophy Doctorate Full Time Mr Benjamin Scott Liffner
    2016 - 2020 Principal Supervisor Investigation of azithromycin analogues and proteasome-like inhibitors as quick-killing antimalarials Doctor of Philosophy Doctorate Full Time Miss Amy Lee Burns
  • Board Memberships

    Date Role Board name Institution name Country
    2016 - 2019 Representative Australian Society for Parasitology, SA Representative Australia
  • Committee Memberships

    Date Role Committee Institution Country
    2017 - ongoing Secretary Molecular Life Sciences Microscopy Committee University of Adelaide Australia
    2016 - 2018 Representative Australian Society for Parasitology, Education Committee Australian Society for Parasitology Australia
    2013 - 2013 Treasurer Malaria in Melbourne Organising Committee Australia
  • Memberships

    Date Role Membership Country
    2017 - ongoing Member Light Microscopy Australia Australia
    2014 - ongoing Member Adelaide Protein Group Australia
    2014 - ongoing Member Australian Society for Biochemistry and Molecular Biology Australia
    2013 - ongoing Representative Australian Society for Parasitology Australia
  • Position: Postdoctoral
  • Phone: 83130413
  • Email: danny.wilson@adelaide.edu.au
  • Fax: 8313 4362
  • Campus: North Terrace
  • Building: Molecular Life Sciences, floor 4
  • Room: 4 13
  • Org Unit: Molecular and Biomedical Science

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