
Associate Professor Christina Bursill
Grant-Funded Researcher (D)
Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Christina Bursill started as leader of the Plaque biology and New blood vessel area in January 2017 at the South Australian Health and Medical Research Institute and as a Senior Research Fellow at The University of Adelaide, Faculty of Health and Medical Sciences. She recently received the inaugural Lin Huddleston National Heart Foundation fellowship. Dr Bursill is a vascular biologist with interests and expertise in vascular inflammation, atherosclerosis and angiogenesis. She completed her PhD at The University of Adelaide in lipid metabolism then headed to Oxford University for five years to undergo a postdoctoral post in the Departments of Cardiovascular Medicine and Pathology. Her postdoctoral time triggered her interest in the mechanisms that cause atherosclerosis and in particular the role of small inflammatory proteins called Chemokines. Christina returned to Australia in 2007 at the Heart Research Institute (HRI) in Sydney where she led the Immunobiology Group. In 2008, Dr Bursill was awarded a National Heart Foundation Career Development Fellowship. At the HRI Dr Bursill developed an interest in high-density lipoproteins (HDL) and through NHMRC/NHF funding investigates novel mechanisms of their action in models of stent biocompatibility, diabetes and wound healing. She also has an interest in using viral gene transfer techniques to over-express proteins that attenuate chemokine activity to suppress atherosclerosis and inflammatory-driven diseases. In 2015 she was awarded the University of Sydney Thompson Fellowship.
- My Research
- Career
- Publications
- Grants and Funding
- Teaching
- Supervision
- Professional Activities
- Contact
Our group is interested in investigating new mechanisms and targets that underlie the development of fatty deposits in the arteries of the heart, a process called atherosclerosis, that causes heart attacks. We also undertake research looking at the regulation of new blood vessel formation (angiogenesis), which can determine how well a heart attack patient recovers. We have a host on pathophysiologically relevant in vitro and in vivo models established in our laboratory.
Project 1
Title: The effect of fenofibrate on wound healing
Description: Human trials have found that the risk of amputation following a foot ulcer is reduced with fenofibrate (Vitamin B) supplementation. In vitro and in vivo studies have also shown that angiogenesis is increased with the addition of fenofibrate. This study will determine if topically applied fenofibrate increases would healing in an in vivo model established in our laboratory.
Project available for: Honours
Location: SAHMRI
Research project start: Semester 1
Project 2
Title: The role of the glycoprotein receptor ASGR1 in unstable atherosclerosis
Description: A GWAS study has identified that a mutation in ASGR1 reduces the risk of a cardiovascular event by 34%. The mechanisms for this are poorly understood and will be investigated using in vitro and in vivo models in this project.
Project available for: Honours
Location: SAHMRI
Research project start: Semester 1
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Appointments
Date Position Institution name 2017 - ongoing Heart Foundation Lin Huddleston Senior Research Fellow University of Adelaide 2017 - ongoing Senior Research Fellow The University of Adelaide -
Language Competencies
Language Competency English Can read, write, speak, understand spoken and peer review -
Education
Date Institution name Country Title The University of Adelaide Australia BSc The University of Adelaide Australia Hons 1 University of Adelaide, Adelaide Australia PhD -
Postgraduate Training
Date Title Institution Country 2017 Leader Plaque Biology and New Blood Vessel Area South Australian Health and Medical Research Institute, Adelaide Australia 2010 - 2016 Leader Immunobiology Group The Heart Research Institute, Newtown Australia 2007 - 2010 Senior Research Officer The Heart Research Institute, Newtown Australia 2001 - 2006 Postdoctoral Fellow University of Oxford, Oxford United Kingdom -
Research Interests
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Journals
Year Citation 2022 Fernando, S., Salagaras, T., Schwarz, N., Sandeman, L., Tan, J. T. M., Xie, J., . . . Psaltis, P. J. (2022). Eukaryotic elongation factor 2 kinase regulates foam cell formation via translation of CD36. The FASEB Journal, 36(2), e22154-1-e22154-19.
2022 Li, J., Thiele, S., Kirk, R. W., Quirk, B. C., Hoogendoorn, A., Chen, Y. C., . . . McLaughlin, R. A. (2022). 3D-printed micro lens-in-lens for in vivo multimodal microendoscopy. Small, 18(17), 2107032-1-2107032-8.
Scopus5 WoS6 Europe PMC22022 Agbaedeng, T. A., Zacharia, A. L., Iroga, P. E., Rathnasekara, V. M., Munawar, D. A., Bursill, C., & Noubiap, J. J. (2022). Associations between adipokines and atrial fibrillation: A systematic review and meta-analysis. Nutrition, Metabolism and Cardiovascular Diseases, 32(4), 853-862.
Scopus12022 Clare, J., Ganly, J., Bursill, C. A., Sumer, H., Kingshott, P., & de Haan, J. B. (2022). The mechanisms of restenosis and relevance to next generation stent design. Biomolecules, 12(3), 430-1-430-26.
Scopus2 WoS3 Europe PMC32022 Mulangala, J., Akers, E. J., Solly, E. L., Bamhare, P. M., Wilsdon, L. A., Wong, N. K. P., . . . Di Bartolo, B. A. (2022). Pro-Calcific Environment Impairs Ischaemia-Driven Angiogenesis. International Journal of Molecular Sciences, 23(6), 21 pages.
2022 Stanton, K. M., Liu, H., Kienzle, V., Bursill, C., Bao, S., & Celermajer, D. S. (2022). The Effects of Exercise on Plaque Volume and Composition in a Mouse Model of Early and Late Life Atherosclerosis. Frontiers in Cardiovascular Medicine, 9, 837371-1-837371-10.
2022 Vidanapathirana, A. K., Goyne, J. M., Williamson, A. E., Pullen, B. J., Chhay, P., Sandeman, L., . . . Bursill, C. A. (2022). Biological Sensing of Nitric Oxide in Macrophages and Atherosclerosis Using a Ruthenium-Based Sensor. Biomedicines, 10(8), 1807.
Scopus1 WoS1 Europe PMC12022 Bursill, C. A., Smith, N. J., Palpant, N., Tan, I., Sunde, M., Harvey, R. P., . . . Vandenberg, J. I. (2022). Don't Turn Off the Tap! The Importance of Discovery Science to the Australian Cardiovascular Sector and Improving Clinical Outcomes Into the Future. Heart Lung and Circulation, 31(10), 1321-1332.
2022 Li, J., Montarello, N., Hoogendoorn, A., Verjans, J., Bursill, C., Peter, K., . . . Psaltis, P. (2022). Multimodality intravascular imaging of high-risk coronary plaque. JACC: Cardiovascular Imaging, 15(1), 145-159.
Scopus14 WoS12 Europe PMC22022 Kavurma, M. M., Bursill, C., Stanley, C. P., Passam, F., Cartland, S. P., Patel, S., . . . Robinson, D. A. (2022). Endothelial cell dysfunction: Implications for the pathogenesis of peripheral artery disease. Frontiers in Cardiovascular Medicine, 9, 1054576.
2021 Solly, E. L., Psaltis, P. J., Bursill, C. A., & Tan, J. T. M. (2021). The Role of miR-181c in Mechanisms of Diabetes-Impaired Angiogenesis: An Emerging Therapeutic Target for Diabetic Vascular Complications. Frontiers in Pharmacology, 12, 718679-1-718679-16.
Scopus3 WoS2 Europe PMC22021 Nankivell, V. A., Tan, J. T. M., Wilsdon, L. A., Morrison, K. R., Bilu, C., Psaltis, P. J., . . . Brown, A. (2021). Circadian disruption by short light exposure and a high energy diet impairs glucose tolerance and increases cardiac fibrosis in Psammomys obesus. Scientific reports, 11(1), 1-13.
Scopus6 WoS6 Europe PMC12021 Watts, G. F., Sullivan, D. R., Hare, D. L., Kostner, K. M., Horton, A. E., Bell, D. A., . . . Psaltis, P. (2021). Essentials of a new clinical practice guidance on familial hypercholesterolaemia for physicians.. Intern Med J, 51(5), 769-779.
Scopus2 WoS2 Europe PMC12021 Watts, G. F., Sullivan, D. R., Hare, D. L., Kostner, K. M., Horton, A. E., Bell, D. A., . . . Pang, J. (2021). Synopsis of an Integrated Guidance for Enhancing the Care of Familial Hypercholesterolaemia: an Australian Perspective. American Journal of Preventive Cardiology, 6, 100151-1-100151-9.
2021 Hoogendoorn, A., Avery, T. D., Li, J., Bursill, C., Abell, A., & Grace, P. M. (2021). Emerging therapeutic applications for fumarates. Trends in Pharmacological Sciences, 42(4), 239-254.
Scopus8 WoS9 Europe PMC62021 Morrison, K. R., Solly, E. L., Shemesh, T., Psaltis, P. J., Nicholls, S. J., Brown, A., . . . Tan, J. T. M. (2021). Elevated HDL-bound miR-181c-5p level is associated with diabetic vascular complications in Australian Aboriginal people. Diabetologia, 64(6), 1402-1411.
Scopus3 WoS4 Europe PMC42021 Pisaniello, A. D., Psaltis, P. J., King, P. M., Liu, G., Gibson, R. A., Tan, J. T. M., . . . Di Bartolo, B. A. (2021). Omega-3 fatty acids ameliorate vascular inflammation: a rationale for their atheroprotective effects. Atherosclerosis, 324, 27-37.
Scopus16 WoS15 Europe PMC82021 Ravindran, D., Galougahi, K. K., Tan, J. T. M., Kavurma, M. M., & Bursill, C. A. (2021). The Multiple Roles of Chemokines in the Mechanisms of Stent Biocompatibility.. Cardiovasc Res, 117(11), 2299-2308.
Scopus2 Europe PMC22021 Vidanapathirana, A. K., Psaltis, P. J., Bursill, C. A., Abell, A. D., & Nicholls, S. J. (2021). Cardiovascular bioimaging of nitric oxide: achievements, challenges, and the future. Medicinal research reviews, 41(1), 435-463.
Scopus13 WoS12 Europe PMC52020 Lotfollahi, Z., Dawson, J., Fitridge, R., & Bursill, C. (2020). The anti-inflammatory and pro-angiogenic properties of high-density lipoproteins (HDL): an emerging role in diabetic wound healing.. Adv Wound Care (New Rochelle), 10(7), 370-380.
Scopus5 WoS4 Europe PMC32020 Watts, G. F., Sullivan, D. R., Hare, D. L., Kostner, K. M., Horton, A. E., Bell, D. A., . . . FH Australasia Network Consensus Working Group. (2020). Integrated Guidance for Enhancing the Care of Familial Hypercholesterolaemia in Australia.. Heart Lung Circ, 30(3), 324-349.
Scopus26 WoS28 Europe PMC142020 Li, J., Thiele, S., Quirk, B. C., Kirk, R. W., Verjans, J. W., Akers, E., . . . McLaughlin, R. A. (2020). Ultrathin monolithic 3D printed optical coherence tomography endoscopy for preclinical and clinical use. Light: Science and Applications, 9(1), 124-1-124-10.
Scopus44 WoS44 Europe PMC42020 Primer, K. R., Psaltis, P. J., Tan, J. T. M., & Bursill, C. A. (2020). The Role of High-Density Lipoproteins in Endothelial Cell Metabolism and Diabetes-Impaired Angiogenesis.. Int J Mol Sci, 21(10), 1-21.
Scopus11 WoS11 Europe PMC72020 Khalid, A., Bai, D., Abraham, A. N., Jadhav, A., Linklater, D., Matusica, A., . . . Gibson, B. C. (2020). Electrospun nanodiamond-silk fibroin membranes: a multifunctional platform for biosensing and wound-healing applications. ACS Appl Mater Interfaces, 12(43), 48408-48419.
Scopus27 WoS26 Europe PMC62020 Li, J., Thiele, S., Quirk, B. C., Kirk, R. W., Verjans, J. W., Akers, E., . . . McLaughlin, R. A. (2020). Ultrathin monolithic 3D printed optical coherence tomography endoscopy for preclinical and clinical use.. Light, science & applications, 9(1), 124.
2019 Takata, K., Honda, S., Sidharta, S. L., MyNgan, D., Shishikura, D., Kim, S. W., . . . Nicholls, S. J. (2019). Associations of ABCG1-mediated cholesterol efflux capacity with coronary artery lipid content assessed by near-infrared spectroscopy. CARDIOVASCULAR DIAGNOSIS AND THERAPY, 9(4), 310.
Scopus7 WoS6 Europe PMC42019 Liu, G., Bursill, C., Cartland, S. P., Anwer, A. G., Parker, L. M., Zhang, K., . . . Goldys, E. M. (2019). A nanoparticle-based affinity sensor that identifies and selects highly cytokine-secreting cells. iScience, 20, 137-147.
Scopus10 WoS11 Europe PMC42019 Ravindran, D., Cartland, S. P., Bursill, C. A., & Kavurma, M. M. (2019). Broad-spectrum chemokine inhibition blocks inflammation-induced angiogenesis, but preserves ischemia-driven angiogenesis.. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(12), 13423-13434.
Scopus5 WoS4 Europe PMC32019 Tan, J. T. M., Nankivell, V. A., Bilu, C., Shemesh, T., Nicholls, S. J., Zimmet, P., . . . Bursill, C. A. (2019). High-Energy Diet and Shorter Light Exposure Drives Markers of Adipocyte Dysfunction in Visceral and Subcutaneous Adipose Depots of Psammomys obesus.. Int J Mol Sci, 20(24), 17 pages.
Scopus7 WoS7 Europe PMC32019 Solly, E. L., Dimasi, C. G., Bursill, C. A., Psaltis, P. J., & Tan, J. T. M. (2019). MicroRNAs as therapeutic targets and clinical biomarkers in atherosclerosis. Journal of Clinical Medicine, 8(12), 2199-1-2199-26.
Scopus33 WoS35 Europe PMC182019 Vidanapathirana, A. K., Pullen, B. J., Zhang, R., Duong, M. N., Goyne, J. M., Zhang, X., . . . Psaltis, P. J. (2019). A novel ruthenium-based molecular sensor to detect endothelial nitric oxide. Scientific Reports, 9(1), 1720-1-1720-16.
Scopus5 WoS5 Europe PMC42019 Yuan, J., Tan, J. T. M., Rajamani, K., Solly, E. L., King, E. J., Lecce, L., . . . Ng, M. K. C. (2019). Fenofibrate rescues diabetes-related impairment of ischemia-mediated angiogenesis by PPARα-independent modulation of thioredoxin-interacting protein. Diabetes, 68(5), 1040-1053.
Scopus11 WoS10 Europe PMC62019 Toledo-Flores, D., Williamson, A., Schwarz, N., Fernando, S., Dimasi, C., Witt, T. A., . . . Psaltis, P. J. (2019). Vasculogenic properties of adventitial Sca-1⁺CD45⁺ progenitor cells in mice: a potential source of vasa vasorum in atherosclerosis. Scientific Reports, 9(1), 7286-1-7286-15.
Scopus15 WoS14 Europe PMC52019 MacEr-Wright, J. L., Stanley, N. R., Portman, N., Tan, J. T., Bursill, C., Rayner, B. S., & Hawkins, C. L. (2019). A role for chlorinated nucleosides in the perturbation of macrophage function and promotion of inflammation. Chemical Research in Toxicology, 32(6), 1223-1234.
Scopus6 WoS4 Europe PMC12019 Nguyen, M. T., Fernando, S., Schwarz, N., Tan, J. T. M., Bursill, C. A., & Psaltis, P. J. (2019). Inflammation as a therapeutic target in atherosclerosis. Journal of Clinical Medicine, 8(8), 1109-1-1109-20.
Scopus86 WoS81 Europe PMC412018 Ridiandries, A., Tan, J. T. M., & Bursill, C. A. (2018). The role of chemokines in wound healing. International Journal of Molecular Sciences, 19(10), 20 pages.
Scopus167 WoS156 Europe PMC992018 Wong, N., Nicholls, S., Tan, J., & Bursill, C. (2018). The role of high-density lipoproteins in diabetes and its vascular complications. International Journal of Molecular Sciences, 19(6), 21 pages.
Scopus27 WoS21 Europe PMC132018 Wong, N. K. P., Cheung, H., Solly, E. L., Vanags, L. Z., Ritchie, W., Nicholls, S. J., . . . Tan, J. T. M. (2018). Exploring the roles of CREBRF and TRIM2 in the regulation of angiogenesis by high-density lipoproteins. International Journal of Molecular Sciences, 19(7), 1903-1-1903-17.
Scopus9 WoS9 Europe PMC52018 Clayton, Z., Tan, R., Miravet, M., Lennartsson, K., Cooke, J., Bursill, C., . . . Patel, S. (2018). Induced pluripotent stem cell-derived endothelial cells promote angiogenesis and accelerate wound closure in a murine excisional wound healing model. Bioscience Reports, 38(4), BSR20180563-1-BSR20180563-11.
Scopus38 WoS37 Europe PMC212018 Hourigan, S. T., Solly, E. L., Nankivell, V. A., Ridiandries, A., Weimann, B., Henriquez, R., . . . Tan, J. T. M. (2018). The regulation of miRNAs by reconstituted high-density lipoproteins in diabetes-impaired angiogenesis. Scientific Reports, 8(1), 13596.
Scopus15 WoS13 Europe PMC112018 Duong, M., Uno, K., Nankivell, V., Bursill, C., & Nicholls, S. (2018). Induction of obesity impairs reverse cholesterol transport in ob/ob mice. PLoS ONE, 13(9), 17 pages.
Scopus17 WoS10 Europe PMC72018 Di Bartolo, B., Psaltis, P., Bursill, C., & Nicholls, S. (2018). Translating evidence of HDL and plaque regression. Arteriosclerosis, thrombosis, and vascular biology, 38(9), 1961-1968.
Scopus16 WoS18 Europe PMC102018 Vanags, L., Wong, N., Nicholls, S., & Bursill, C. (2018). High-density lipoproteins and apolipoprotein A-I improve stent biocompatibility: recent evidence from experimental models and clinical studies. Arteriosclerosis, Thrombosis, and Vascular Biology, 38(8), 1691-1701.
Scopus10 WoS9 Europe PMC92018 Cannizzo, C. M., Adonopulos, A. A., Solly, E. L., Ridiandries, A., Vanags, L. Z., Mulangala, J., . . . Tan, J. T. (2018). VEGFR2 is activated by high-density lipoproteins and plays a key role in the proangiogenic action of HDL in ischemia. FASEB Journal, 32(6), 2911-2922.
Scopus8 WoS8 Europe PMC72018 Chen, X., Duong, M., Nicholls, S., & Bursill, C. (2018). Myeloperoxidase modification of high-density lipoprotein suppresses human endothelial cell proliferation and migration via inhibition of ERK1/2 and Akt activation. Atherosclerosis, 273, 75-83.
Scopus7 WoS7 Europe PMC22018 Vanags, L. Z., Tan, J. T. M., Galougahi, K. K., Schaefer, A., Wise, S. G., Murphy, A., . . . Bursill, C. A. (2018). Apolipoprotein A-I Reduces In-Stent Restenosis and Platelet Activation and Alters Neointimal Cellular Phenotype. JACC: Basic to Translational Science, 3(2), 200-209.
Scopus13 WoS12 Europe PMC92018 Morton, J., Bao, S., Vanags, L., Tsatralis, T., Ridiandries, A., Siu, C., . . . Bursill, C. (2018). Strikingly different atheroprotective effects of apolipoprotein A-I in early- versus late-stage atherosclerosis. JACC: Basic to Translational Science, 3(2), 187-199.
Scopus12 WoS11 Europe PMC82017 Chen, X., Duong, M., Psaltis, P., Bursill, C., & Nicholls, S. (2017). High-density lipoproteins attenuate high glucose-impaired endothelial cell signaling and functions: potential implications for improved vascular repair in diabetes. Cardiovascular Diabetology, 16(1), 121-1-121-9.
Scopus13 WoS15 Europe PMC132017 Chalmers, A., Bursill, C., & Myerscough, M. (2017). Nonlinear dynamics of early atherosclerotic plaque formation may determine the efficacy of high density lipoproteins (HDL) in plaque regression. PLoS ONE, 12(11), e0187674-1-e0187674-23.
Scopus18 WoS14 Europe PMC82017 Chung, R., Wang, Z., Bursill, C., Wu, B., Barter, P., & Rye, K. (2017). Effect of long-term dietary sphingomyelin supplementation on atherosclerosis in mice. PLoS ONE, 12(12), 1-13.
Scopus23 WoS20 Europe PMC72017 Vanags, L., Tan, J., Santos, M., Michael, P., Ali, Z., Bilek, M., . . . Bursill, C. (2017). Plasma activated coating immobilizes apolipoprotein A-I to stainless steel surfaces in its bioactive form and enhances biocompatibility. Nanomedicine: Nanotechnology, Biology, and Medicine, 13(7), 2141-2150.
Scopus6 WoS6 Europe PMC42017 Ridiandries, A., Bursill, C., & Tan, J. (2017). Broad-spectrum inhibition of the CC-chemokine class improves wound healing and wound angiogenesis. International Journal of Molecular Sciences, 18(1), 155-1-155-15.
Scopus22 WoS19 Europe PMC132017 Ridiandries, A., Tan, J., Ravindran, D., Williams, H., Medbury, H., Lindsay, L., . . . Bursill, C. (2017). CC-chemokine class inhibition attenuates pathological angiogenesis while preserving physiological angiogenesis. FASEB Journal, 31(3), 1179-1192.
Scopus13 WoS12 Europe PMC122017 van der Vorst, E., Theodorou, K., Wu, Y., Hoeksema, M., Goossens, P., Bursill, C., . . . Donners, M. (2017). High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-κB/STAT1-IRF1 Signaling. Cell Metabolism, 25(1), 197-207.
Scopus59 WoS55 Europe PMC372017 Tan, J. T. M., Prosser, H. C. G., Dunn, L. L., Vanags, L. Z., Ridiandries, A., Tsatralis, T., . . . Bursill, C. A. (2017). High-Density Lipoproteins Rescue Diabetes-Impaired Angiogenesis via Scavenger Receptor Class B Type I (vol 65, pg 3091, 2016). DIABETES, 66(4), 1 page.
2017 Ravindran, D., Ridiandries, A., Vanags, L., Henriquez, R., Cartland, S., Tan, J., & Bursill, C. (2017). Chemokine binding protein 'M3' limits atherosclerosis in apolipoprotein E-/- mice. PLoS ONE, 12(3), e0173224-1-e0173224-23.
Scopus15 WoS14 Europe PMC92017 Chan, A., Tan, R., Michael, P., Lee, B., Vanags, L., Ng, M., . . . Wise, S. (2017). Evaluation of synthetic vascular grafts in a mouse carotid grafting model. PLoS ONE, 12(3), e0174773-1-e0174773-15.
Scopus14 WoS13 Europe PMC92016 Arnott, C., Punnia-Moorthy, G., Tan, J., Sadeghipour, S., Bursill, C., & Patel, S. (2016). The Vascular Endothelial Growth Factor Inhibitors Ranibizumab and Aflibercept Markedly Increase Expression of Atherosclerosis-Associated Inflammatory Mediators on Vascular Endothelial Cells. PLOS ONE, 11(3), e0150688.
Scopus17 WoS20 Europe PMC122016 Ridiandries, A., Tan, J., & Bursill, C. (2016). The role of CC-chemokines in the regulation of angiogenesis. International Journal of Molecular Sciences, 17(11), 1856-1-1856-16.
Scopus68 WoS66 Europe PMC462016 Tsatralis, T., Ridiandries, A., Robertson, S., Vanags, L., Lam, Y., Tan, J. T., . . . Bursill, C. (2016). Reconstituted high-density lipoproteins promote wound repair and blood flow recovery in response to ischemia in aged mice. Lipids in Health and Disease, 15(1), 150-1-150-12.
Scopus10 WoS8 Europe PMC52016 Tan, J., Prosser, H., Dunn, L., Vanags, L., Ridiandries, A., Tsatralis, T., . . . Bursill, C. (2016). High-density lipoproteins rescue diabetes-impaired angiogenesis via scavenger receptor Class B Type I. Diabetes, 65(10), 3091-3103.
Scopus30 WoS27 Europe PMC222016 Lam, Y., Lecce, L., Tan, J., Bursill, C., Handelsman, D., & Ng, M. (2016). Androgen receptor-mediated genomic androgen action augments ischemia-induced neovascularization. Endocrinology, 157(12), 4853-4864.
Scopus5 WoS6 Europe PMC42016 Robertson, S., Martínez, G., Payet, C., Barraclough, J., Celermajer, D., Bursill, C., & Patel, S. (2016). Colchicine therapy in acute coronary syndrome patients acts on caspase-1 to suppress NLRP3 inflammasome monocyte activation. Clinical Science, 130(14), 1237-1246.
Scopus88 WoS79 Europe PMC422015 Martínez, G., Robertson, S., Barraclough, J., Xia, Q., Mallat, Z., Bursill, C., . . . Patel, S. (2015). Colchicine acutely suppresses local cardiac production of inflammatory cytokines in patients with an acute coronary syndrome. Journal of the American Heart Association, 4(8), e002128-1-e002128-10.
Scopus180 WoS183 Europe PMC982015 Chalmers, A., Cohen, A., Bursill, C., & Myerscough, M. (2015). Bifurcation and dynamics in a mathematical model of early atherosclerosis: how acute inflammation drives lesion development. Journal of Mathematical Biology, 71(6), 1451-1480.
Scopus32 WoS25 Europe PMC122015 Kim, C., Mitchell, J., Bursill, C., Sowers, A., Thetford, A., Cook, J., . . . Davies, M. (2015). The nitroxide radical TEMPOL prevents obesity, hyperlipidaemia, elevation of inflammatory cytokines, and modulates atherosclerotic plaque composition in apoE¯⁄¯mice. Atherosclerosis, 240(1), 234-241.
Scopus41 WoS37 Europe PMC222015 Tan, J., Ng, M., & Bursill, C. (2015). The role of high-density lipoproteins in the regulation of angiogenesis. Cardiovascular Research, 106(2), 184-193.
Scopus25 WoS24 Europe PMC162014 Dunn, L., Simpson, P., Prosser, H., Lecce, L., Yuen, G., Buckle, A., . . . Ng, M. (2014). A critical role for Thioredoxin- Interacting protein in diabetes-related impairment of angiogenesis. Diabetes, 63(2), 675-687.
Scopus50 WoS46 Europe PMC362014 Brown, B., Kim, C., Torpy, F., Bursill, C., McRobb, L., Heather, A., . . . Van Reyk, D. (2014). Supplementation with carnosine decreases plasma triglycerides and modulates atherosclerotic plaque composition in diabetic apo E-/- mice. Atherosclerosis, 232(2), 403-409.
Scopus47 WoS46 Europe PMC312014 Prosser, H., Tan, J., Dunn, L., Patel, S., Vanags, L., Bao, S., . . . Bursill, C. (2014). Multifunctional regulation of angiogenesis by high-density lipoproteins. Cardiovascular Research, 101(1), 145-154.
Scopus40 WoS37 Europe PMC292014 Tan, J., Hamish, H., Vanags, L., Monger, S., Ng, M., & Bursill, C. (2014). High-density lipoproteins augment hypoxia-induced angiogenesis via regulation of post-translational modulation of hypoxia-inducible factor 1α. FASEB Journal, 28(1), 206-217.
Scopus43 WoS37 Europe PMC342013 Van Der Vorst, E., Vanags, L., Dunn, L., Prosser, H., Rye, K., & Bursill, C. (2013). High-density lipoproteins suppress chemokine expression and proliferation in human vascular smooth muscle cells. FASEB Journal, 27(4), 1413-1425.
Scopus41 WoS38 Europe PMC302013 Dunn, L., Prosser, H., Tan, J., Vanags, L., Ng, M., & Bursill, C. (2013). Murine model of wound healing. Journal of Visualized Experiments, 2013(75), 1-6.
Scopus148 WoS138 Europe PMC582013 Dunn, L., Prosser, H., Tan, J., Vanags, L., Ng, M., & Bursill, C. (2013). Murine model of wound healing. Journal of visualized experiments : JoVE, (75), e50265.
Scopus442013 Ali, Z. A., Rinze, R., Douglas, G., Hu, Y., Xiao, Q., Qi, W., . . . Channon, K. M. (2013). Tetrahydrobiopterin determines vascular remodeling through enhanced endothelial cell survival and regeneration. Circulation, 128(SUPPL.1), S50-S58.
Scopus17 WoS16 Europe PMC122012 Prosser, H., Ng, M., & Bursill, C. (2012). The role of cholesterol efflux in mechanisms of endothelial protection by HDL. Current Opinion in Lipidology, 23(3), 182-189.
Scopus51 WoS49 Europe PMC392011 Akram, O. N., Bursill, C., Desai, R., Heather, A. K., Kazlauskas, R., Handelsman, D. J., & Lambert, G. (2011). Evaluation of androgenic activity of nutraceutical-derived steroids using mammalian and yeast in vitro androgen bioassays. Analytical Chemistry, 83(6), 2065-2074.
Scopus37 WoS37 Europe PMC182011 Di Bartolo, B., Vanags, L., Tan, J., Bao, S., Rye, K., Barter, P., & Bursill, C. (2011). The apolipoprotein A-I mimetic peptide, ETC-642, reduces chronic vascular inflammation in the rabbit.. Lipids in health and disease, 10(1), 224.
Scopus22 WoS20 Europe PMC152011 Di Bartolo, B., Nicholls, S., Bao, S., Rye, K., Heather, A., Barter, P., & Bursill, C. (2011). The apolipoprotein A-I mimetic peptide ETC-642 exhibits anti-inflammatory properties that are comparable to high density lipoproteins. Atherosclerosis, 217(2), 395-400.
Scopus51 WoS52 Europe PMC402010 Bursill, C. A., Castro, M. L., Beattie, D. T., Nakhla, S., Van Der Vorst, E., Heather, A. K., . . . Rye, K. A. (2010). High-density lipoproteins suppress chemokines and chemokine receptors in vitro and in vivo. Arteriosclerosis, Thrombosis, and Vascular Biology, 30(9), 1773-1778.
Scopus107 WoS101 Europe PMC812009 Rye, K. A., Bursill, C. A., Lambert, G., Tabet, F., & Barter, P. J. (2009). The metabolism and anti-atherogenic properties of HDL. Journal of Lipid Research, 50(SUPPL.), S195-S200.
Scopus225 WoS221 Europe PMC1452009 Seki, E., De Minicis, S., Gwak, G. Y., Kluwe, J., Inokuchi, S., Bursill, C. A., . . . Schwabe, R. F. (2009). CCR1 and CCR5 promote hepatic fibrosis in mice. Journal of Clinical Investigation, 119(7), 1858-1870.
Scopus347 WoS322 Europe PMC2562009 Bursill, C. A., McNeill, E., Wang, L., Hibbitt, O. C., Wade-Martins, R., Paterson, D. J., . . . Channon, K. M. (2009). Lentiviral gene transfer to reduce atherosclerosis progression by long-term CC-chemokine inhibition. Gene Therapy, 16(1), 93-102.
Scopus32 WoS31 Europe PMC222009 Stevenson, N. J., Addley, M. R., Ryan, E. J., Boyd, C. R., Carroll, H. P., Paunovic, V., . . . Johnston, J. A. (2009). CCL11 blocks IL-4 and GM-CSF signaling in hematopoietic cells and hinders dendritic cell differentiation via suppressor of cytokine signaling expression. Journal of Leukocyte Biology, 85(2), 289-297.
Scopus29 WoS29 Europe PMC212008 McAteer, M. A., Schneider, J. E., Ali, Z. A., Warrick, N., Bursill, C. A., Von Zur Muhlen, C., . . . Choudhury, R. P. (2008). Magnetic resonance imaging of endothelial adhesion molecules in mouse atherosclerosis using dual-targeted microparticles of iron oxide. Arteriosclerosis, Thrombosis, and Vascular Biology, 28(1), 77-83.
Scopus217 WoS201 Europe PMC1322008 Ali, Z. A., Bursill, C. A., Douglas, G., McNeil, E., Papaspyridonos, M., Tatham, A. L., . . . Channon, K. M. (2008). CCR2-mediated antiinflammatory effects of endothelial tetrahydrobiopterin inhibit vascular injury-induced accelerated atherosclerosis. Circulation, 118(14 Suppl), S71-S77.
2007 Bursill, C. A., & Roach, P. D. (2007). A green tea catechin extract upregulates the hepatic low-density lipoprotein receptor in rats. Lipids, 42(7), 621-627.
Scopus45 WoS47 Europe PMC222007 Hibbitt, O. C., Harbottle, R. P., Waddington, S. N., Bursill, C. A., Coutelle, C., Channon, K. M., & Wade-Martins, R. (2007). Delivery and long-term expression of a 135 kb LDLR genomic DNA locus in vivo by hydrodynamic tail vein injection. Journal of Gene Medicine, 9(6), 488-497.
Scopus40 WoS35 Europe PMC252007 Bursill, C. A., Abbey, M., & Roach, P. D. (2007). A green tea extract lowers plasma cholesterol by inhibiting cholesterol synthesis and upregulating the LDL receptor in the cholesterol-fed rabbit. Atherosclerosis, 193(1), 86-93.
Scopus118 WoS96 Europe PMC512006 Bursill, C. A., & Roach, P. D. (2006). Modulation of cholesterol metabolism by the green tea polyphenol (-)-epigallocatechin gallate in cultured human liver (HepG2) cells. Journal of Agricultural and Food Chemistry, 54(5), 1621-1626.
Scopus83 WoS74 Europe PMC412006 Ali, T., Humphries, J., Burnand, K., Sawyer, B., Bursill, C., Channon, K., . . . Smith, A. (2006). Monocyte recruitment in venous thrombus resolution. Journal of Vascular Surgery, 43(3), 601-608.
Scopus64 WoS61 Europe PMC482006 Bursill, C. A., Cash, J. L., Channon, K. M., & Greaves, D. R. (2006). Membrane-bound CC chemokine inhibitor 35k provides localized inhibition of CC chemokine activity in vitro and in vivo. Journal of Immunology, 177(8), 5567-5573.
Scopus16 WoS15 Europe PMC102005 Ali, Z. A., Bursill, C. A., Hu, Y., Choudhury, R. P., Xu, Q., Greaves, D. R., & Channon, K. M. (2005). Gene transfer of a broad spectrum CC-chemokine inhibitor reduces vein graft atherosclerosis in apolipoprotein E-knockout mice. Circulation, 112(9 SUPPL.), I235-I241.
Scopus39 WoS34 Europe PMC202005 Puhakka, H. L., Turunen, P., Gruchala, M., Bursill, C., Heikura, T., Vajanto, I., . . . Ylä-Herttuala, S. (2005). Effects of vaccinia virus anti-inflammatory protein 35K and TIMP-1 gene transfers on vein graft stenosis in rabbits. In Vivo, 19(3), 515-522.
Scopus21 WoS18 Europe PMC102004 Bursill, C. A., Channon, K. M., & Greaves, D. R. (2004). The role of chemokines in atherosclerosis: Recent evidence from experimental models and population genetics. Current Opinion in Lipidology, 15(2), 145-149.
Scopus97 WoS87 Europe PMC782004 Bursill, C. A., Choudhury, R. P., Ali, Z., Greaves, D. R., & Channon, K. M. (2004). Broad-spectrum CC-chemokine blockade by gene transfer inhibits macrophage recruitment and atherosclerotic plaque formation in apolipoprotein E-knockout mice. Circulation, 110(16), 2460-2466.
Scopus63 WoS61 Europe PMC422003 Lucas, A. D., Bursill, C., Guzik, T. J., Sadowski, J., Channon, K. M., & Greaves, D. R. (2003). Smooth Muscle Cells in Human Atherosclerotic Plaques Express the Fractalkine Receptor CX<inf>3</inf>CR1 and Undergo Chemotaxis to the CX <inf>3</inf>C Chemokine Fractalkine (CX<inf>3</inf>CL1). Circulation, 108(20), 2498-2504.
Scopus141 WoS134 Europe PMC992003 Bursill, C. A., Cai, S., Channon, K. M., & Greaves, D. R. (2003). Adenoviral-mediated delivery of a viral chemokine binding protein blocks CC-chemokine activity in vitro and in vivo. Immunobiology, 207(3), 187-196.
Scopus35 WoS35 Europe PMC202001 Bursill, C., Roach, P., Bottema, C., & Pal, S. (2001). Green tea upregulates the low-density lipoprotein receptor through the sterol-regulated element binding protein in HepG2 liver cells. Journal of Agricultural and Food Chemistry, 49(11), 5639-5645.
Scopus54 WoS42 Europe PMC21 -
Book Chapters
Year Citation 2020 Nankivell, V., Primer, K., Vidanapathirana, A., Psaltis, P., & Bursill, C. (2020). Vascular Biology of Smooth Muscle Cells and Restenosis. In R. Fitridge (Ed.), Mechanisms of Vascular Disease A Textbook for Vascular Specialists (3rd ed., pp. 117-139). Cham, Switzerland: Springer. -
Conference Papers
Year Citation 2022 Nankivell, V. A., Vidanapathirana, A., Rajora, M., Psaltis, P., Tan, J. T., Tieu, W., . . . Bursill, C. A. (2022). Theranostic Properties of Porphysome Nanoparticles in Atherosclerotic Cardiovascular Disease. In CIRCULATION Vol. 146 (pp. 3 pages). Chicago, IL: LIPPINCOTT WILLIAMS & WILKINS. 2022 Primer, K. R., Tan, J. T., Psaltis, P. J., & Bursill, C. A. (2022). Pyruvate Dehydrogenase Kinase 4 is a Novel Regulator of Endothelial Cell Mitochondrial Respiration in Diabetes-Impaired Angiogenesis: Implications for Preventing Diabetic Vascular Complications. In CIRCULATION Vol. 146 (pp. 2 pages). Chicago, IL: LIPPINCOTT WILLIAMS & WILKINS. 2022 Lotfollahi, Z., Tan, J. T., Dawson, J., Fitridge, R., & Bursill, C. A. (2022). Tracking High-Density Lipoprotein Functionality in Diabetic and Non-Diabetic Patients With Toe Amputations. In CIRCULATION Vol. 146 (pp. 2 pages). Chicago, IL: LIPPINCOTT WILLIAMS & WILKINS. 2022 Pullen, B. J., Vidanapathirana, A. K., Sandeman, L., Everest-Dass, A., Kolarich, D., Tan, J. T., . . . Bursill, C. A. (2022). Deletion of the Asialyloglycoprotein Receptor-1 Causes Athero-Protective Effects in vitro and in vivo. In CIRCULATION Vol. 146 (pp. 2 pages). Chicago, IL: LIPPINCOTT WILLIAMS & WILKINS. 2022 Solly, E. L., Mulangala, J., Di Bartolo, B. A., Nicholls, S. J., Psaltis, P. J., Bursill, C. A., & Tan, J. T. M. (2022). Inhibition of microRNA-181c rescues diabetes-impaired angiogenesis through activation of key angiogenesis mediators. In DIABETOLOGIA Vol. 65 (pp. S25-S26). Stockholm, SWEDEN: SPRINGER. 2019 Khalid, A., Abraham, A. N., Bai, D., Jadhav, A., Linklater, D., Nguyen, D., . . . Gibson, B. (2019). Electrospun diamond-silk membranes for biosensing applications. In Proceedings of SPIE - The International Society for Optical Engineering Vol. 11202 (pp. 1-5). online: SPIE.
2019 Pisaniello, A. D., King, P., Di Bartolo, B. A., Liu, G., Gibson, R. A., Tan, J. T. M., . . . Nicholls, S. (2019). IMPACT OF FISH OIL SUPPLEMENTATION ON ACUTE VASCULAR INFLAMMATION IN HEALTHY VOLUNTEERS. In JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol. 73 (pp. 2091). New Orleans, LA: ELSEVIER SCIENCE INC.
2017 Cannizzo, C. M., Adonopulos, A. A., Ridiandries, A., Vanags, L. Z., Yuen, S. C. G., Tsatralis, T., . . . Tan, J. T. (2017). VEGFR2 is Activated by High-Density Lipoproteins and Plays a Key Role in the Pro-Angiogenic Action of HDL in Ischemia. In CIRCULATION Vol. 136 (pp. 1 page). Anaheim, CA: LIPPINCOTT WILLIAMS & WILKINS. 2017 Hourigan, S. T., Ridiandries, A., Tepper, E. R., Zhang, J. Q., Henriquez, R., Tsatralis, T., . . . Tan, J. T. (2017). The Regulation of miRNAs in rHDL-Induced Rescue of Diabetes-Impaired Angiogenesis. In CIRCULATION Vol. 136 (pp. 1 page). Anaheim, CA: LIPPINCOTT WILLIAMS & WILKINS. 2017 Van Der Vorst, E., Theodorou, K., Wu, Y., Hoeksema, M., Goossens, P., Bursill, C., . . . Donners, M. (2017). HIGH DENSITY LIPOPROTEINS EXERT PRO-INFLAMMATORY EFFECTS ON MACROPHAGES VIA PASSIVE CHOLESTEROL DEPLETION AND PKC-NF-KB/STAT1-IRF1 SIGNALING. In ATHEROSCLEROSIS Vol. 263 (pp. E6). Prague, CZECH REPUBLIC: ELSEVIER IRELAND LTD.
WoS12008 Ali, Z. A., Bursill, C. A., Douglas, G., McNeill, E., Papaspyridonos, M., Tatham, A. L., . . . Channon, K. M. (2008). CCR2-mediated antiinflammatory effects of endothelial tetrahydrobiopterin inhibit vascular injury-induced accelerated atherosclerosis.. In Circulation Vol. 118 (pp. S71-S77). Orlando, FL: LIPPINCOTT WILLIAMS & WILKINS.
Scopus31 WoS30 Europe PMC19 -
Conference Items
Year Citation 2019 Fernando, S., Schwarz, N., Sandeman, L., Skoumbourdis, T., Zareh, J., Williamson, A., . . . Psaltis, P. J. (2019). Eukaryotic Elongation Factor 2 Kinase Regulates Cholesterol Uptake by Macrophages via Cd36 Scavenger Receptor Expression. Poster session presented at the meeting of CIRCULATION. Philadelphia, PA: LIPPINCOTT WILLIAMS & WILKINS. 2019 Wong, N. K., Solly, E., Nicholls, S., Psaltis, P., Ng, M. K., Bursill, C. A., & Tan, J. T. (2019). TRIM2 and CREBRF Are Novel Regulators of Angiogenic Functions in Human Coronary Artery Endothelial Cells. Poster session presented at the meeting of CIRCULATION. Philadelphia, PA: LIPPINCOTT WILLIAMS & WILKINS. 2019 Akers, E. J., Mulangala, J., Wilsdon, L. A., Psaltis, P. J., Bursill, C. A., Nicholls, S. J., & Di Bartolo, B. A. (2019). Lipoproteins and Their Modified Forms Regulate Early Stage Vascular Smooth Muscle Cell Calcification. Poster session presented at the meeting of ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. Boston, MA: LIPPINCOTT WILLIAMS & WILKINS. 2019 Williamson, A., Toledo, D., Schwarz, N., Fernando, S., Dimasi, C., Liyanage, S., . . . Psaltis, P. (2019). Postnatal mouse aorta contains yolk sac-derived haemangioblasts with myeloid and endothelial plasticity and vasculogenic capacity. Poster session presented at the meeting of European Heart Journal. Paris, France: Oxford University Press. 2018 Takata, K., Duong, M., Honda, S., Sidharta, S. L., Kim, S. W., Shishikura, D., . . . Nicholls, S. J. (2018). Association of Apolipoprotein C-III Distribution With Cholesterol Efflux Capacity and Coronary Plaque Burden. Poster session presented at the meeting of CIRCULATION. LIPPINCOTT WILLIAMS & WILKINS. 2018 Duong, M., Nankivell, V., Bursill, C. A., & Nicholls, S. J. (2018). Obesity Impairs Reverse Cholesterol Transport in Ob/Ob Mice.. Poster session presented at the meeting of CIRCULATION. LIPPINCOTT WILLIAMS & WILKINS. 2016 Tan, J., Hourigan, S., Zhang, J., Wong, N., Tepper, E., Prosser, H., . . . Bursill, C. (2016). miRNA-181c and its putative target TRIM2 mediate the ability of high density lipoproteins to rescue diabetes-impaired angiogenesis. Poster session presented at the meeting of as published in Diabetes. New Orleans, LA: American Diabetes Association. 2015 Tan, J. T. M., Prosser, H. C. G., Dunn, L. L., Vanags, L. Z., Ridiandries, A., Tsatralis, T., . . . Bursill, C. A. (2015). High Density Lipoproteins Rescue Diabetes-Impaired Angiogenesis via Scavenger Receptor-BI and Restoration of VEGF and HIF-1 alpha Stability. Poster session presented at the meeting of DIABETES. Boston, MA: AMER DIABETES ASSOC.
WoS12014 Van der Vorst, E. P. C., Theodorou, K., Plat, J., Van Eck, M., Rye, K. A., Bursill, C. A., . . . Donners, M. M. P. C. (2014). High density lipoproteins exert pro-inflammatory effects on macrophages via IKK2-and NIK-independent NF-kB activation. Poster session presented at the meeting of CARDIOVASCULAR RESEARCH. Barcelona, SPAIN: OXFORD UNIV PRESS.
2013 Prosser, H. C., Tan, J. T., Dunn, L. L., Patel, S., Vanags, L. Z., Monger, S., . . . Bursill, C. A. (2013). Multifunctional Regulation of Angiogenesis by High Density Lipoproteins. Poster session presented at the meeting of CIRCULATION. Dallas, TX: LIPPINCOTT WILLIAMS & WILKINS. 2013 Morton, J., Bao, S., Celermajer, D. S., Ng, M. K., & Bursill, C. A. (2013). Strikingly Different Atheroprotective Effects of Apolipoprotein A-I in Early-Stage Versus Late-Stage Atherosclerosis. Poster session presented at the meeting of CIRCULATION. Dallas, TX: LIPPINCOTT WILLIAMS & WILKINS.
WoS12012 Quigley, A. F., Summers, F. A., Barrett, T. J., Bursill, C. A., & Hawkins, C. L. (2012). A novel role of myeloperoxidase in the induction of endoplasmic reticulum (ER) stress. Poster session presented at the meeting of FREE RADICAL BIOLOGY AND MEDICINE. ELSEVIER SCIENCE INC.
2012 Quigley, A. F., Summers, F. A., Barrett, T. J., Bursill, C. A., & Hawkins, C. L. (2012). A Novel Role for Myeloperoxidase in the Induction of C/EBP-Homologous Protein (CHOP). Poster session presented at the meeting of FREE RADICAL BIOLOGY AND MEDICINE. San Diego, CA: ELSEVIER SCIENCE INC.
·National Heart Foundation Lin Huddleston Foundation Fellowship (2017-2022)
Chief Investigator: Christina Bursill (CIA)
Amount: ~$750,000 over 5 years
·Diabetes Australia Research (DART) grant (2017)
Title: ‘Micromanaging’ high-density lipoprotein-induced rescue of diabetes-impaired angiogenesis
Chief Investigators: Joanne Tan and Christina Bursill
Amount: $60,000
· NAB Career Re-start Grant (2016)
Title: Reversing the progression of atherosclerosis
Chief Investigators: Christina Bursill (CIA),
Amount: $60,000 over one year
· ARC Discovery Grant (2016)
Title: Dynamics of atherosclerotic plaque formation, growth and regression
Chief Investigators: Mary Myerscough (CIA), Charlie Macaskill (CIB), Christina Bursill (PI).
Amount: $218,768 over three years
· University of Sydney - Thompson Fellowship (2016)
Title: Using the "Good Cholesterol" to increase stent longevity
Chief Investigator: Christina Bursill (CIA)
Amount: $90, 000 over one year
· University of Sydney Bridging Grant (2015)
Title: Different athero-protective properties of HDL in early versus late atherosclerosis
Chief Investigators: Christina Bursill (CIA)
Amount: $30, 000 over 1 year
· NHMRC Project Grant (2015)
Title: Oxidative Regulation of the Na pump – a new player in vascular function in health and disease.
Chief Investigators: Gemma Figtree (CIA), Christina Bursill (CIB), A/Prof Ravinay Bhindi (CIC), Prof Keith Channon (CID), A/Prof Clare Hawkins (CIE), Dr Ben Davies (CIF), Prof Richard Cohen (CIG).
Amount: $488,816 over three years
· University of Sydney Bridging Grant (2013)
Title: Differential Regulation of Angiogenesis by CC-Chemokines
Chief Investigators: Christina Bursill (CIA)
Amount: $30, 000 over 1 year
· NHMRC project grant (2010-2013)
Title: Multifunctional regulation of Angiogenesis by High Density Lipoproteins
Chief Investigators: Martin Ng (CIA), Christina Bursill (CIB)
Amount: $476, 000 over 3 years
· Heart Foundation Career Development Fellowship (2008-2013)
Title: The Role of Chemokines in the Anti-Atherosclerotic Effects of HDL
Chief Investigator: Christina Bursill
Amount: $515,000 – includes 5 years salary, travel funds and equipment support.
·Bushell Foundation (2008-2011)
Title: Understanding the Anti-Atherosclerotic Properties of High Density Lipoproteins
Investigator: Christina Bursill
Amount: $250, 000 over 3 years
· British Heart Foundation Program Grant (2005-2007):
Title: Evaluation of Broad Spectrum Chemokine agonists to Inhibit Atherosclerosis
Investigators: Keith Channon, David Greaves, and Christina Bursill
Amount: £715,961 over 5 years
· British Heart Foundation Project Grant (2001-2004):
Title: Evaluation of Broad Spectrum CC-Chemokine antagonists to Inhibit Inflammatory Cell Recruitment in Atherogenesis.
Investigators: David Greaves, Keith Channon, and Christina Bursill
Amount: £152,326 over 3 years. Based on the success of the project, the initial grant was extended for a further 2.5 years (£126,939) based on my research.
Undergraduate Teaching:
·1997-98: Tutor for 1st year Medical students in Problem Based Learning, Department of Medicine, University of Adelaide.
·1998-2000: Demonstrator for 2nd year Science students in Cardiovascular Physiology, Department of Physiology, University of Adelaide.
·2001: Lecturer to 2nd year Medical students on Lipoprotein Metabolism, Department of Pathology, University of Oxford, UK.
·2001, 2002: Demonstrator for 2nd year Medical Students in Atherosclerosis and Thrombosis, Department of Pathology, University of Oxford, UK.
·2004-2006: Lecturer to 3rd year Medical students in ‘Methods and Approach in Scientific Research’. Department of Medicine, University of Oxford, UK.
·2015-2026: Lecturer to 3rd year Physiology students on “Vascular Inflammation”, University of Sydney, NSW.
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2023 Principal Supervisor Immune Subsets in Chronic Rhinosinusitis in Relation to the Sinonasal Microbiome Doctor of Philosophy Doctorate Full Time Mr Demeke Geremew Debebe 2022 Co-Supervisor Multimodal imaging probe for atherosclerotic plaque detection Doctor of Philosophy Doctorate Full Time Miss Rouyan Chen 2019 Principal Supervisor The Role of Metabolic Reprogramming in Diabetes-Impaired Angiogenesis Doctor of Philosophy Doctorate Full Time Miss Khalia Rose Primer 2019 Co-Supervisor MicroRNA-181c - A Novel Therapeutic Target for te Rescue of Diabetes-Impaired Angiogenesis Doctor of Philosophy Doctorate Full Time Miss Emma Louise Solly 2019 Co-Supervisor Investigating Novel Mediators of Angiogenesis and Inflammation Doctor of Philosophy Doctorate Full Time Ms Sanuri Rashmitha Liyanage 2018 Principal Supervisor Tracking Apolipoprotein Linked Porphyrin Liposomes in Atherosclerosis and Stent Models Doctor of Philosophy Doctorate Full Time Miss Victoria Ann Nankivell 2018 Principal Supervisor Investigation of the LIPID-Independent Cardioprotective effects elicited by loss of function of the Asialoglycoprotein Receptor Doctor of Philosophy Doctorate Full Time Mr Benjamin James Pullen -
Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2018 - 2022 Principal Supervisor The Anti-Inflammatory and Pro-Angiogenic Capacity of High-Density Lipoproteins in Diabetic Wound Healing Doctor of Philosophy Doctorate Full Time Ms Zahra Lotfollahi 2018 - 2022 Co-Supervisor Discovery and characterisation of yolk-sac derived Endothelial-Macrophage progenitor cells in postnatal murine tissues Doctor of Philosophy Doctorate Full Time Miss Anna Emilie Williamson 2017 - 2021 Co-Supervisor Vascular Calcification as a Risk Factor for Peripheral Arterial Disease and its Effects on Angiogenesis Doctor of Philosophy Doctorate Full Time Ms Jocelyne Mulangala
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Committee Memberships
Date Role Committee Institution Country 2018 - ongoing President Australian Atherosclerosis Society N/A Australia -
Editorial Boards
Date Role Editorial Board Name Institution Country 2014 - ongoing Associate Editor Journal of Biochemistry - - 2013 - ongoing Associate Editor PLoS ONE - -
Connect With Me
External Profiles