Dr Chris Brien
Senior Biostatistician
School of Agriculture, Food and Wine
Faculty of Sciences
Welcome to my profile. My main research interest is the design and analysis of experiments, particularly the class of experiments that I have termed multitiered. I am also interested in the formulation of mixed models for the analysis of designed experiments, including the analysis of longitudinal experiments. I originally graduated from the University of Sydney with an agricultural science degree majoring in Biometry. I started my professional life as a consulting Biometrician with what was then the CSIRO Division of Horticultural Research, designing and analyzing viticultural, sensory and other laboratory experiments. After 6 years with CSIRO I went to Roseworthy Agricultural College for a 10 year stint as a lecturer/consultant in statistics for agriculture, natural resources and oenology. During this time I completed a M.Ag.Sc. and began a PhD, both majoring in Biometry at the University of Adelaide. My last move was in 1988 to the Institute of Technology, one of the institutions that in 1991 became the University of South Australia. Here I was a Senior Lecturer in Statistics in the School of Mathematics and Statistics and I lectured/consulted in statistics in areas such as business, engineering, environmental sciences, library studies, physiotherapy and computer science. In February 2006 I, and my colleague Prof. Rosemary Bailey from The University of St Andrews, Scotland, presented a read paper entitled Multiple randomizations to the prestigious Royal Statistical Society in London.
I retired from the University of South Australia in November 2009, but I am continuing my research and consulting as an Adjunct Senior Lecturer in the Phenomics and Bioinformatics Research Centre and, since 2015, as Senior Biometrician at the Plant Accelerator in the School of Agriculture, Food and Wine at the University of Adelaide. In addition to continuing my work on multitiered experiments, I am currently working on the design and analysis of agricultural and other biological experiments. Particular areas of experimentation in which I work are in high-throughput, phenotyping experiments (see Brien et al. (2013) or Al-Tamimi et al. (2016)) and sugarcane breeding experiments. Click here for my Curriculum Vitae (in a pdf file).
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Journals
Year Citation 2019 Ward, B., Brien, C., Oakey, H., Pearson, A., Negrão, S., Schilling, R., . . . van den Hengel, A. (2019). High‐throughput 3D modelling to dissect the genetic control of leaf elongation in barley (Hordeum vulgare). The Plant Journal, OnlinePubl(3), 1-16.
2019 Pham, A., Maurer, A., Pillen, K., Brien, C., Dowling, K., Berger, B., . . . March, T. (2019). Genome-wide association of barley plant growth under drought stress using a nested association mapping population. BMC Plant Biology, 19(1), 16 pages.
2018 Asif, M., Schilling, R., Tilbrook, J., Brien, C., Dowling, K., Rabie, H., . . . Pearson, A. (2018). Mapping of novel salt tolerance QTL in an Excalibur × Kukri doubled haploid wheat population. TAG Theoretical and Applied Genetics, 131(10), 2179-2196.
Scopus12018 Sapdhare, H., Myers, B., Beecham, S., & Brien, C. (2018). Performance of a kerb side inlet to irrigate street trees and to improve road runoff water quality: a comparison of four media types. Environmental Science and Pollution Research.
2018 Yichie, Y., Brien, C., Berger, B., Roberts, T., & Atwell, B. (2018). Salinity tolerance in Australian wild Oryza species varies widely and matches that observed in O. sativa. Rice, 11(1), 14 pages.
2017 Brien, C., & Payne, R. (2017). Graham Neil Wilkinson 1927-2016 Obituary. JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY, 180(3), 930-931.
2017 Ferdous, J., Whitford, R., Nguyen, M., Brien, C., Langridge, P., & Tricker, P. (2017). Drought-inducible expression of Hv-miR827 enhances drought tolerance in transgenic barley. Functional and Integrative Genomics, 17(2-3), 279-292.
Scopus12 WoS10 Europe PMC32017 Ferdous, J., Sanchez-Ferrero, J., Langridge, P., Milne, L., Chowdhury, J., Brien, C., & Tricker, P. (2017). Differential expression of microRNAs and potential targets under drought stress in barley. Plant, Cell & Environment, 40(1), 11-24.
Scopus24 WoS23 Europe PMC122017 Meng, R., Saade, S., Kurtek, S., Berger, B., Brien, C., Pillen, K., . . . Sun, Y. (2017). Growth curve registration for evaluating salinity tolerance in barley. Plant Methods, 13(1), 18-1-18-9.
Scopus2 WoS1 Europe PMC12017 Atieno, J., Li, Y., Langridge, P., Dowling, K., Brien, C., Berger, B., . . . Sutton, T. (2017). Exploring genetic variation for salinity tolerance in chickpea using image-based phenotyping. Scientific Reports, 7(1), 11 pages.
Scopus9 WoS9 Europe PMC62017 Campbell, M., Du, Q., Liu, K., Brien, C., Berger, B., Zhang, C., & Walia, H. (2017). A comprehensive image-based phenomic analysis reveals the complex genetic architecture of shoot growth dynamics in rice (Oryza sativa). Plant Genome, 10(2), 1-14.
Scopus8 WoS6 Europe PMC22017 Tilbrook, J., Schilling, R., Berger, B., Garcia, A., Trittermann, C., Coventry, S., . . . Roy, S. (2017). Variation in shoot tolerance mechanisms not related to ion toxicity in barley. Functional Plant Biology, 44(12), 1194-1206.
Scopus3 WoS3 Europe PMC12017 Brien, C. (2017). Multiphase experiments in practice: A look back. Australian and New Zealand Journal of Statistics, 59(4), 327-352.
2016 Shirdelmoghanloo, H., Taylor, J., Lohraseb, I., Rabie, H., Brien, C., Timmins, A., . . . Collins, N. (2016). A QTL on the short arm of wheat (Triticum aestivum L.) chromosome 3B affects the stability of grain weight in plants exposed to a brief heat shock early in grain filling. BMC Plant Biology, 16(1), 100-1-100-15.
Scopus12 WoS12 Europe PMC42016 Hardner, C., Evans, K., Brien, C., Bliss, F., & Peace, C. (2016). Genetic architecture of apple fruit quality traits following storage and implications for genetic improvement. Tree Genetics and Genomes, 12(2), 20-1-20-21.
Scopus8 WoS72016 Bailey, R., & Brien, C. (2016). Randomization-based models for multitiered experiments: I. A chain of randomizations. Annals of Statistics, 44(3), 1131-1164.
Scopus4 WoS62016 Shirdelmoghanloo, H., Lohraseb, I., Rabie, H., Brien, C., Parent, B., & Collins, N. (2016). Heat susceptibility of grain filling in wheat (Triticum aestivum L.) linked with rapid chlorophyll loss during a 3-day heat treatment. Acta Physiologiae Plantarum, 38(8), 208-1-208-11.
Scopus2 WoS22016 Al-Tamimi, N., Brien, C., Oakey, H., Berger, B., Saade, S., Ho, Y., . . . Negrão, S. (2016). Salinity tolerance loci revealed in rice using high-throughput non-invasive phenotyping. Nature Communications, 7, 13342-1-13342-11.
Scopus36 WoS34 Europe PMC282015 Campbell, M., Knecht, A., Berger, B., Brien, C., Wang, D., & Walia, H. (2015). Integrating image-based phenomics and association analysis to dissect the genetic architecture of temporal salinity responses in rice. Plant Physiology, 168(4), 1476-1489.
Scopus46 WoS42 Europe PMC232014 Razzaghmanesh, M., Beecham, S., & Brien, C. (2014). Developing resilient green roofs in a dry climate. Science of the Total Environment, 490, 579-589.
Scopus17 WoS15 Europe PMC22013 Demétrio, C., Menten, J., Leandro, R., & Brien, C. (2013). Experimental power considerations-Justifying replication for animal care and use committees. Poultry Science, 92(9), 2490-2497.
Scopus4 WoS3 Europe PMC32013 Brien, C., Berger, B., Rabie, H., & Tester, M. (2013). Accounting for variation in designing greenhouse experiments with special reference to greenhouses containing plants on conveyor systems. Plant Methods, 9(1), 1-22.
Scopus23 WoS19 Europe PMC122012 Smith, G., Brien, C., & Ashman, H. (2012). Evaluating implicit judgments from image search clickthrough data. Journal of the American Society for Information Science and Technology, 63(12), 2451-2462.
Scopus14 WoS92012 Brien, C. (2012). Comments on 'Therapist variation within randomized trials of psychotherapy: Implications for precision, internal and external validity'. Statistical Methods in Medical Research, 21(2), 215-216.
Scopus1 WoS12012 Brien, C. J., Bailey, R. A., Tran, T. T., & Boland, J. (2012). Quasi-Latin designs. Electronic Journal of Statistics, 6(0), 1900-1925.
2012 Atkinson, A. C., Vandebroek, M., Berger, M. P., Morgan, J., Bailey, R., Waite, T., . . . Tsai, P. -W. (2012). Optimum design of experiments for statistical inference Discussion. JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS, 61, 369-401. 2011 Brien, C., Harch, B., Correll, R., & Bailey, R. (2011). Multiphase Experiments with at Least One Later Laboratory Phase. I. Orthogonal Designs. Journal of Agricultural, Biological, and Environmental Statistics, 16(3), 422-450.
Scopus17 WoS152010 Brien, C., & Bailey, R. (2010). Decomposition tables for experiments. II. TWO-ONE randomizations. Annals of Statistics, 38(5), 3164-3190.
Scopus6 WoS62010 Brito E Abreu, S., Brien, C., & Skinner, W. (2010). ToF-SIMS as a new method to determine the contact angle of mineral surfaces. Langmuir, 26(11), 8122-8130.
Scopus23 WoS172009 Brien, C., & Bailey, R. (2009). Decomposition tables for experiments I. A chain of randomizations. Annals of Statistics, 37(6 B), 4184-4213.
Scopus10 WoS102009 Brien, C., & Demétrio, C. (2009). Formulating mixed models for experiments, including longitudinal experiments. Journal of Agricultural, Biological, and Environmental Statistics, 14(3), 253-280.
Scopus19 WoS192009 Butler, D., Tan, M., & Cullis, B. (2009). Improving the accuracy of selection for late maturity alpha-amylase in wheat using multi-phase designs. CROP & PASTURE SCIENCE, 60(12), 1202-1208.
WoS82008 Gross, M., Brien, C., & Brown, G. (2008). Examining the dimensions of a lifestyle tourism destination. International Journal of Culture, Tourism and Hospitality Research, 2(1), 44-66.
Scopus232008 Wilkinson, R., Frisina, C., Partington, D., Franz, P., Brien, C., Thomson, F., . . . Faragher, J. (2008). Effects of 1-methylcyclopropene on firmness and flesh browning in Pink Lady™ apples. Journal of Horticultural Science and Biotechnology, 83(2), 165-170.
Scopus5 WoS52006 Brien, C., & Bailey, R. (2006). Multiple randomizations. Journal of the Royal Statistical Society. Series B: Statistical Methodology, 68(4), 571-609.
Scopus40 WoS392002 Searle, S. (2002). A first course in the design of experiments: A linear models approach. CONTEMPORARY PSYCHOLOGY-APA REVIEW OF BOOKS, 47(6), 720-722. 1999 Brien, C., & Payne, R. (1999). Tiers, structure formulae and the analysis of complicated experiments. Journal of the Royal Statistical Society Series D: The Statistician, 48(1), 41-52.
Scopus13 WoS101998 Brien, C., & Demétrio, C. (1998). Using the randomisation in specifying the ANOVA model and table for properly and improperly replicated grazing trials. Australian Journal of Experimental Agriculture, 38(4), 325-334.
Scopus4 WoS41996 David, G., Dvir, Z., Mackintosh, S., & Brien, C. (1996). Validity study of a novel test protocol for the identification of submaximal muscular effort. Isokinetics and Exercise Science, 6(2), 139-144.
Scopus9 WoS91996 Trott, P., Pearcy, M., Ruston, S., Fulton, I., & Brien, C. (1996). Three-dimensional analysis of active cervical motion: The effect of age and gender. Clinical Biomechanics, 11(4), 201-206.
Scopus108 WoS94 Europe PMC661995 Scutter, S., Fulton, I., Trott, P., Parnianpour, M., Grant, R., & Brien, C. (1995). Effects of various isoresistive training programmes on trunk muscle performance. Clinical Biomechanics, 10(7), 379-384.
Scopus8 WoS3 Europe PMC31989 BRIEN, C. (1989). A MODEL COMPARISON APPROACH TO LINEAR-MODELS. UTILITAS MATHEMATICA, 36, 225-254.
WoS71988 Brien, C., James, A., & Venables, W. (1988). An analysis of correlation matrices: Variables cross-classified by two factors. Biometrika, 75(3), 469-476.
Scopus3 WoS31987 BRIEN, C., MAY, P., & MAYO, O. (1987). Analysis of Judge Performance in Wine‐Quality Evaluations. Journal of Food Science, 52(5), 1273-1279.
Scopus25 WoS20 Europe PMC31985 EWART, A., BRIEN, C., SODERLUND, R., & SMART, R. (1985). THE EFFECTS OF LIGHT PRUNING, IRRIGATION AND IMPROVED SOIL-MANAGEMENT ON WINE QUALITY OF THE VITIS-VINIFERA CV RIESLING. VITIS, 24(4), 209-217.
WoS111985 SMART, R., ROBINSON, J., DUE, G., & BRIEN, C. (1985). CANOPY MICROCLIMATE MODIFICATION FOR THE CULTIVAR SHIRAZ .1. DEFINITION OF CANOPY MICROCLIMATE. VITIS, 24(1), 17-31.
WoS611985 SMART, R., ROBINSON, J., DUE, G., & BRIEN, C. (1985). CANOPY MICROCLIMATE MODIFICATION FOR THE CULTIVAR SHIRAZ .2. EFFECTS ON MUST AND WINE COMPOSITION. VITIS, 24(2), 119-128.
WoS1131984 Brien, C., Venables, W., James, A., & Mayo, O. (1984). An analysis of correlation matrices: Equal correlations. Biometrika, 71(3), 545-554.
Scopus26 WoS241983 Brien, C. (1983). Analysis of variance tables based on experimental structure.. Biometrics, 39(1), 53-59.
Scopus24 WoS14 Europe PMC41982 BRUER, B., BRUER, D., & BRIEN, C. (1982). SHELF-LIFE OF SOME COMMON WINERY LABORATORY REAGENTS. AMERICAN JOURNAL OF ENOLOGY AND VITICULTURE, 33(3), 159-163. 1982 MAY, P., CLINGELEFFER, P., & BRIEN, C. (1982). PRUNING OF SULTANA VINES TO LONG SPURS. AMERICAN JOURNAL OF ENOLOGY AND VITICULTURE, 33(4), 214-221.
WoS51980 CLINGELEFFER, P., MAY, P., & BRIEN, C. (1980). THE EFFECTS OF MIXING TURGID (BLOB) AND DRIED SULTANAS DURING STORAGE. FOOD TECHNOLOGY IN AUSTRALIA, 32(7), 332-&.
WoS31978 May, P., Clingelefer, P., Brien, C., & Scholejield, P. (1978). Harvest pruning of young sultana vines under various training systems. Australian Journal of Experimental Agriculture, 18(95), 847-854.
Scopus3 WoS51978 May, P., Clingeleffer, P., & Brien, C. (1978). Pruning Sultana vines by the arched cane system. Australian Journal of Experimental Agriculture, 18(91), 301-308.
Scopus2 WoS51978 HALE, C., & BRIEN, C. (1978). INFLUENCE OF SALT CREEK ROOTSTOCK ON COMPOSITION AND QUALITY OF SHIRAZ GRAPES AND WINE. VITIS, 17(2), 139-146.
WoS231977 CLINGELEFFER, P., TRAYFORD, R., MAY, P., & BRIEN, C. (1977). USE OF STARWHEEL SPRAYER FOR APPLYING DRYING EMULSION TO SULTANA GRAPES TO BE DRIED ON TRELLIS. AUSTRALIAN JOURNAL OF EXPERIMENTAL AGRICULTURE, 17(88), 871-880.
WoS21976 MAY, P., CLINGELEFFER, P., SCHOLEFIELD, P., & BRIEN, C. (1976). RESPONSE OF GRAPE CULTIVAR CROUCHEN (AUSTRALIAN SYN CLARE-RIESLING) TO VARIOUS TRELLIS AND PRUNING TREATMENTS. AUSTRALIAN JOURNAL OF AGRICULTURAL RESEARCH, 27(6), 845-856.
WoS151975 LOVEYS, B., BRIEN, C., & KRIEDEMANN, P. (1975). Biosynthesis of Abscisic Acid under Osmotic Stress: Studies Based on a Dual Labelling Technique. Physiologia Plantarum, 33(2), 166-170.
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Conference Papers
Year Citation 1988 BRIEN, J., BRIEN, J., & BRIEN, C. (1988). NEW AUSTRALIAN AGRICULTURAL INFORMATION RESOURCE. In D. WEDEMEYER, & M. OGDEN (Eds.), TELECOMMUNICATIONS AND PACIFIC DEVELOPMENT : ALTERNATIVES FOR THE NEXT DECADE Vol. 11 (pp. 369-374). HONOLULU, HI: ELSEVIER SCIENCE PUBL B V. 1978 BRIEN, C. (1978). DISCRETE MULTIVARIATE-ANALYSIS WITH PARTICULAR REFERENCE TO A DESIGN EXPERIMENT. In BIOMETRICS Vol. 34 (pp. 169). INTERNATIONAL BIOMETRIC SOC.
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