Cheryl Brown

Dr Cheryl Brown

Grant-Funded Researcher (B)

School of Pharmacy and Biomedical Science

College of Health

Eligible to supervise Masters and PhD - email supervisor to discuss availability.


Dr Cheryl Y. BrownThe University of Adelaide - Research Scientist in the field of T cell immunology.Women's and Children's Hospital and the Robinson Research Institute.Fred Hutchinson Cancer Research Center - USA, Post doctoral scientist Feb 1998 – Dec 2003. Medical research in the field of Apoptosis/cancer research.University of Washington, Seattle, Washington, USA - Post doctoral scientist Jul 1996 – Feb 1998 Post-doctoral research scientist in a lab studying regulation of translation.Research assistant - National Institute for Medical Research, London. Apr 1987 – Mar 1989. Schistosomiasis research.

Date Institution name Country Title
1992 - 1996 University of Adelaide Australia PhD
1990 - 1991 University College London/ London School of Hygiene and Tropical Medicine United Kingdom MSc General and Medical Microbiology

Year Citation
2023 Wong, Y. Y., Harbison, J. E., Hope, C. M., Gundsambuu, B., Brown, K. A., Wong, S. W., . . . Barry, S. C. (2023). Parallel recovery of chromatin accessibility and gene expression dynamics from frozen human regulatory T cells. Scientific reports, 13(1), 5506-1-5506-15.
DOI Scopus8 WoS8 Europe PMC11
2020 Brown, C. Y., Sadlon, T., Hope, C. M., Wong, Y. Y., Wong, S., Liu, N., . . . Barry, S. C. (2020). Molecular Insights Into Regulatory T-Cell Adaptation to Self, Environment, and Host Tissues: Plasticity or Loss of Function in Autoimmune Disease. Frontiers in Immunology, 11(September), 1-17.
DOI Scopus15 WoS16 Europe PMC14
2019 Hope, C. M., Welch, J., Mohandas, A., Pederson, S., Hill, D., Gundsambuu, B., . . . Barry, S. C. (2019). Peptidase inhibitor 16 identifies a human regulatory T-cell subset with reduced FOXP3 expression over the first year of recent onset type 1 diabetes. European Journal of Immunology, 49(8), 1235-1250.
DOI Scopus21 WoS21 Europe PMC21
2018 Penington, J. S., Penno, M., Ngui, K., Ajami, N., Roth-Schulze, A., Wilcox, S., . . . Giles, L. (2018). Influence of fecal collection conditions and 16S rRNA gene sequencing protocols at two centers on human gut microbiota analysis. Scientific Reports, 8, 10 pages.
DOI
2018 Sadlon, T., Brown, C. Y., Bandara, V., Hope, C. M., Schjenken, J. E., Pederson, S. M., . . . Barry, S. C. (2018). Unravelling the molecular basis for regulatory T-cell plasticity and loss of function in disease. Clinical and Translational Immunology, 7(2), e1011-1-e1011-15.
DOI Scopus27 WoS23 Europe PMC21
2018 Penington, J., Penno, M., Ngui, K., Ajami, N., Roth-Schulze, A., Wilcox, S., . . . Vuillermin, P. (2018). Influence of fecal collection conditions and 16S rRNA gene sequencing at two centers on human gut microbiota analysis. Scientific Reports, 8(1), 4386-1-4386-10.
DOI Scopus45 WoS44 Europe PMC41
2018 Brown, C. Y., Dayan, S., Wong, S. W., Kaczmarek, A. K., Hope, C. M., Pederson, S. M., . . . Barry, S. C. (2018). FOXP3 and miR-155 cooperate to control the invasive potential of human breast cancer cells by down regulating ZEB2 independently of ZEB1. Oncotarget, 9(45), 27708-27727.
DOI Scopus20 Europe PMC18
2012 Hill, D., Eastaff-Leung, N., Bresatz-Atkins, S., Warner, N., Ruitenberg, J., Krumbiegel, D., . . . Barry, S. (2012). Inhibition of activation induced CD154 on CD4⁺ CD25⁻ cells: a valid surrogate for human Treg suppressor function. Immunology and Cell Biology, 90(8), 812-821.
DOI Scopus13 WoS11 Europe PMC10
2012 McInnes, N., Sadlon, T., Brown, C., Pederson, S., Beyer, M., Schultze, J., . . . Barry, S. (2012). FOXP3 and FOXP3-regulated microRNAs suppress SATB1 in breast cancer cells. Oncogene, 31(8), 1045-1054.
DOI Scopus93 WoS85 Europe PMC75
2010 Brown, C., Sadlon, T., Gargett, T., Melville, E., Zhang, R., Drabsch, Y., . . . Barry, S. (2010). Robust, reversible gene knockdown using a single lentiviral short hairpin RNA vector. Human Gene Therapy, 21(8), 1005-1017.
DOI Scopus27 WoS28 Europe PMC24
2010 Sadlon, T., Wilkinson, B., Pederson, S., Brown, C., Bresatz, S., Gargett, T., . . . Barry, S. (2010). Genome-wide identification of human FOXP3 target genes in natural regulatory T cells. Journal of Immunology, 185(2), 1071-1081.
DOI Scopus124 WoS122 Europe PMC112
2009 Hutton, J., Gargett, T., Sadlon, T., Bresatz, S., Brown, C., Zola, H., . . . Barry, S. (2009). Development of CD4⁺CD25⁺FoxP3⁺ regulatory T cells from cord blood hematopoietic progenitor cells. Journal of Leukocyte Biology, 85(3), 445-451.
DOI Scopus29 WoS20 Europe PMC21
2002 Putland, R., Sassinis, T., Harvey, J., Diamond, P., Coles, L., Brown, C., & Goodall, G. (2002). RNA destabilization by the granulocyte colony-stimulating factor stem-loop destabilizing element involves a single stem-loop that promotes deadenylation. Molecular and Cellular Biology, 22(6), 1664-1673.
DOI Scopus35 WoS33 Europe PMC30
1999 Brown, C. Y., Mize, G. J., Pineda, M., George, D. L., & Morris, D. R. (1999). Role of two upstream open reading frames in the translational control of oncogene mdm2. Oncogene, 18(41), 5631-5637.
DOI Scopus95 Europe PMC81
1996 Brown, C. Y., Lagnado, C. A., & Goodall, G. J. (1996). A cytokine mRNA-destabilizing element that is structurally and functionally distinct from A+U-rich elements. Proceedings of the National Academy of Sciences of the United States of America, 93(24), 13721-13725.
DOI Scopus65 WoS66 Europe PMC55
1996 Brown, C. Y., Lagnado, C. A., Vadas, M. A., & Goodall, G. J. (1996). Differential regulation of the stability of cytokine mRNAs in lipopolysaccharide-activated blood monocytes in response to interleukin-10. Journal of Biological Chemistry, 271(33), 20108-20112.
DOI Scopus90 WoS86 Europe PMC66
1994 Lagnado, C. A., Brown, C. Y., & Goodall, G. J. (1994). AUUUA is not sufficient to promote poly(A) shortening and degradation of an mRNA: The functional sequence within AU-rich elements may be UUAUUUA(U/A)(U/A). Molecular and Cellular Biology, 14(12), 7984-7995.
DOI Scopus320 WoS323 Europe PMC246

Date Role Research Topic Program Degree Type Student Load Student Name
2023 Principal Supervisor Investigating the role of JAZF1 in the formation and function of human induced Regulatory T cells Doctor of Philosophy Doctorate Full Time Miss Hannah Rae Morgan
2023 Co-Supervisor Investigating regulatory T cells post COVID-19 Doctor of Philosophy Doctorate Full Time Ms Sarah May Battersby
2023 Principal Supervisor Investigating the role of JAZF1 in the formation and function of human induced Regulatory T cells Doctor of Philosophy Doctorate Full Time Miss Hannah Rae Morgan
2023 Co-Supervisor Investigating regulatory T cells post COVID-19 Doctor of Philosophy Doctorate Full Time Ms Sarah May Battersby

Date Role Research Topic Program Degree Type Student Load Student Name
2016 - 2021 Co-Supervisor A NOVEL ROLE FOR ZEB2 AS A LINEAGE FIDELITY CHECKPOINT IN HUMAN CD4+ T CELLS Doctor of Philosophy Doctorate Full Time Mr Soon Wei Wong

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