APrf Branka Grubor-Bauk
Internal Grant-Funded Researcher (D)
School of Medicine
College of Health
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
A/Prof Grubor-Bauk is the Head of Viral Immunology Group at the Adelaide Medical School. She trained as a virologist, immunologist, and vaccine scientist and after postdoctoral training and a period in Biotech, she now leads a collaborative research program which encompasses discovery and translational science components.
Multidisciplinary approach of our group covers areas of translational immunology and vaccine development. We collaborate and work closely with clinicians in the areas of long COVID, severe viral respiratory infections, sepsis and vaccination responses in vulnerable populations. Our group is also focussed on development of novel vaccines and vaccine platforms against various pathogens, for human and veterinary use. Recently we have expanded our research portfolio into development of novel mRNA and saRNA vaccines in cancer therapy, as well as in prevention of bacterial infections.
Our group has various commercial research partnerships, with an aim to develop solutions with clinical application.
Student projects
We have various student projects available for Honours, Masters and PhD studies. The projects cover vaccine development (mRNA, saRNA, rAAV) with options for cross-discipline and industry collaborations. Please see the list below for currently available projects.
Prospective students can contact Branka directly via email.
Please note:
Prerequisite: Students must have sound knowledge of immunology in order to undertake these projects.
Available projects:
1) Development of multivalent mRNA and saRNA vaccines
2) Novel mRNA-LNP formulations for optimal vaccine immunogenicity
3) mRNA-LNP biodistribution and tissue targeting
4) Novel mRNA vaccines in cancer therapy
5) Development of mRNA vaccines for induction of gamma delta T cell immunity
6) Liver immunobiology in HCV vaccine development
7) mRNA vaccines against Staph aureus
8) Murray Valley encephalitis virus vaccine development
9) Biomarkers of sepsis and in hospital mortality in ICU patients
10) Biomarkers of Long COVID
11) Immunopathology of Long COVID
11) Innate immunity and LNP/mRNA formulations
12) Impact of prior dengue virus infection on Zika virus infection during pregnancy
| Language | Competency |
|---|---|
| English | - |
| Serbian | - |
| Date | Institution name | Country | Title |
|---|---|---|---|
| 2007 | University of Adelaide, Adelaide | Australia | PhD |
| 1999 | University of Adelaide, Adelaide | Australia | Bachelor of Health Sciences (Honours) |
| 1998 | University of Adelaide, Adelaide | Australia | Bachelor of Science |
| Year | Citation |
|---|---|
| 2017 | Tomusange, K., Wijesundara, D., Gowans, E., & Grubor-Bauk, B. (2017). Human rhinovirus-A1 as an expression vector. In M. C. Ferran, & G. R. Skuse (Eds.), Recombinant Virus Vaccines: Methods and Protocols (Vol. 1581, pp. 181-201). UK: Humana Press. DOI |
| Year | Citation |
|---|---|
| 2025 | Grubor-Bauk, B., Masavuli, M. G., Mekonnen, Z. A., Whelan, D. M., Yeow, A. E. L., Santos, R., . . . O'connor, D. H. (2025). A Safer Alternative: Development of multivalent T cell vaccine against Zika virus \. In JOURNAL OF IMMUNOLOGY Vol. 214 (pp. 165-166). HI, Honolulu: OXFORD UNIV PRESS. DOI |
| 2024 | Chai, C. S., Perkins, G. B., Tunbridge, M., Hope, C., Yeow, A., Salehi, T., . . . Coates, T. (2024). Rapamycin diversifies SARS-CoV-2 specific T cell memory with stem cell phenotype in immunosuppressed kidney transplant recipients. In Abstracts of the 30th International Congress of The Transplantation-Society (TTS, 2024) as published in Transplantation Vol. 108 (pp. 89). Istanbul, Turkey: Lippincott, Williams & Wilkins. |
| 2024 | Sheng Chai, C., Boord Perkins, G., Tunbridge, M., Hope, C., Yeow, A., Salehi, T., . . . Coates, T. (2024). Rapamycin diversifies SARS-CoV-2 specific T cell memory with stem cell phenotype in immunosuppressed kidney transplant recipients.. In TRANSPLANTATION Vol. 108 (pp. 1 page). TURKEY, Istanbul: LIPPINCOTT WILLIAMS & WILKINS. DOI |
| 2022 | Perkins, G., Tunbridge, M., Salehi, T., Chai, C. S., Hope, C. M., Garcia-Valtanen, P., . . . Coates, A. O. T. (2022). MTOR Inhibitors Promote Highly Functional T Cell Immunity in Kidney Transplant Recipients Vaccinated Against COVID-19. In TRANSPLANTATION Vol. 106 (pp. S223). ELECTR NETWORK: LIPPINCOTT WILLIAMS & WILKINS. |
| 2022 | Tunbridge, M. J., Perkins, G., Salehi, T., Grubor-Bauk, B., Sim, B., Ying, T., . . . Coates, P. T. (2022). A Prospective Randomised, Controlled Trial Switching Sirolimus for Mycophenolate to Enhance Immunological Responses to Third Dose COVID-19 Vaccination in Kidney Transplant Recipients with Poor Baseline Humoral Immunity. In AMERICAN JOURNAL OF TRANSPLANTATION Vol. 22 (pp. 1095). ELECTR NETWORK: WILEY. |
| 2022 | Perkins, G. B., Tunbridge, M., Salehi, T., Chai, C., Hope, C. M., Garcia-Valtanen, P., . . . Coates, P. (2022). Sirolimus Use is Associated with an Improved Immune Response to COVID-19 Vaccination in Kidney Transplant Recipients. In AMERICAN JOURNAL OF TRANSPLANTATION Vol. 22 (pp. 873). WILEY. |
| 2021 | Liu, Y., Yue, J., Shi, P., Wang, Y., Gao, H., Feng, B., . . . Li, H. (2021). A Deep Learning Method for LiDAR Bathymetry Waveforms Processing. In Z. Zhang (Ed.), 2021 INTERNATIONAL CONFERENCE ON NEURAL NETWORKS, INFORMATION AND COMMUNICATION ENGINEERING Vol. 11933 (pp. 7 pages). PEOPLES R CHINA, Qingdao: SPIE-INT SOC OPTICAL ENGINEERING. DOI WoS2 |
| 2016 | Wijesundara, D., Grubor-Bauk, B., Gargett, T., Yu, W., & Gowans, E. (2016). A cytolytic DNA vaccine to target cross-presentation of dendritic cells. In EUROPEAN JOURNAL OF IMMUNOLOGY Vol. 46 (pp. 1060-1061). Melbourne, AUSTRALIA: WILEY-BLACKWELL. |
| Year | Citation |
|---|---|
| 2017 | Masavuli, M. G., Wijesundara, D. K., Grubor-Bauk, B., & Gowans, E. J. (2017). Novel DNA vaccine formulations encoding secreted HCV-E1/E2 fused to the IMX313 oligomerisation domain are immunogenic in mice. Poster session presented at the meeting of 12th Annual Scientific Meeting of the Australian Centre for HIV and Hepatitis Virology. |
| 2017 | Masavuli, M. G., Wijesundara, D. K., Grubor-Bauk, B., & Gowans, E. J. (2017). Novel DNA vaccine formulations encoding secreted HCV-E1/E2 fused to the IMX313 oligomerisation domain are immunogenic in mice. Poster session presented at the meeting of Adelaide Immunology Retreat. Nuriootpa. |
| 2017 | Masavuli, M. G., Wijesundara, D. K., Grubor-Bauk, B., & Gowans, E. J. (2017). Novel DNA vaccine formulations encoding secreted HCV-E1/E2 fused to the IMX313 oligomerisation domain are immunogenic in mice. Poster session presented at the meeting of Florey Postgraduate Research Conference. |
| 2017 | Masavuli, M. G., Wijesundara, D. K., Grubor-Bauk, B., & Gowans, E. J. (2017). Enhancing the immunogenicity of HCV vaccines by fusing E1/E2 to the IMX313P multimerization technology. Poster session presented at the meeting of 24th International Symposium on Hepatitis C Virus and Related Viruses. Hyannis, Cape Cod, Massachusetts, USA. |
| 2017 | Masavuli, M. G., Wijesundara, D. K., Grubor-Bauk, B., & Gowans, E. J. (2017). Novel DNA vaccines encoding secreted HCV-E1/E2 fused to the IMX313 oligomerisation domain are immunogenic in mice. Poster session presented at the meeting of The Queen Elizabeth Hospital (TQEH) Research Day. Adeleide, Australia. |
| 2017 | Masavuli, M. G., Wijesundara, D. K., Grubor-Bauk, B., & Gowans, E. J. (2017). Enhancing the immunogenicity of HCV vaccines by fusing E1/E2 to the IMX313P oligomerisation technology. Poster session presented at the meeting of 9th Australasian Virology Society Meeting. |
| 2016 | Tomusange, K., Wijesundara, D., Gummow, J., Gowans, E. J., & Grubor-Bauk, B. (2016). Mucosal vaccination with a live recombinant rhinovirus followed by intradermal DNA administration elicits protective HIV-specific immune responses. Poster session presented at the meeting of Abstracts of the 2016 Conference on HIV Research for Prevention (HIV R4P), as published in Aids Research and Human Retroviruses. Chicago, IL: Mary Ann Liebert. DOI |
| 2016 | Khamis, T., Wijesundara, D., Gummow, J., Garrod, T., Li, Y., Gray, L., . . . Gowans, E. (2016). HIV-Tat Fused to the Oligomerisation Domain of the C4-binding Protein Is Highly Immunogenic and Controls EcoHIV Challenge in Mice. Poster session presented at the meeting of AIDS RESEARCH AND HUMAN RETROVIRUSES. Chicago, IL: MARY ANN LIEBERT, INC. |
| 2016 | Masavuli, M. G., Wijesundara, D. K., Grubor-Bauk, B., & Gowans, E. J. (2016). A novel DNA-based virus-like particle (VLP) vaccine against hepatitis C.. Poster session presented at the meeting of Florey Postgraduate Research Conference. |
| 2016 | Masavuli, M. G., Wijesundara, D. W., Grubor-Bauk, B., & Gowans, E. J. (2016). A DNA-based virus-like particle (VLP) vaccine against the hepatitis C virus. Poster session presented at the meeting of The Queen Elizabeth Hospital (TQEH) Research Day. Adelaide. |
| 2015 | Masavuli, M. G., Grubor-Bauk, B. G., Wijesundara, D. K., & Gowans, E. J. (2015). A novel DNA-based virus-like particle (VLP) vaccine for hepatitis C virus. Poster session presented at the meeting of Florey Postgraduate Research Conference. AdelaIide. |
| 2015 | Masavuli, M. G., Wijesundara, D. K., grubor-bauk, B., & gowans, E. G. (2015). A novel DNA-based virus-like particle vaccine for hepatitis C virus. Poster session presented at the meeting of The Queen Elizabeth Hospital (TQEH) Research Day 2015. Adelaide. |
| 2013 | Loveland, B. E., Latour, P., Roberts, S. K., Gordon, A., Kemp, W., Kitson, M., . . . Gowans, E. J. (2013). A Phase I clinical trial of cellular immunotherapy for persistent Hepatitis C infection. Poster session presented at the meeting of Clinical and Experimental Pharmacology and Physiology. Hangzhou, Peoples Republic of China: Wiley-Blackwell. |
| Year | Citation |
|---|---|
| 2018 | Masavuli, M. G. (2018). Novel DNA Vaccine Formulations Against Hepatitis C Virus. (PhD Thesis). |
| Year | Citation |
|---|---|
| 2025 | Carolin, A., Bishop, C. R., Grubor-Bauk, B., Plummer, M. P., Raith, E., Barry, S. C., . . . Suhrbier, A. (2025). RNA-Seq of Nasopharyngeal Swabs from ICU Patients Infected with SARS-CoV-2 Omicron Sublineages in Adelaide, Australia, 2022–2023. DOI |
| 2024 | Sinclair, J., Vedelago, C., Ryan, F., Carney, M., Lynn, M., Grubor-Bauk, B., . . . Short, K. (2024). Cardiovascular symptoms of PASC are associated with trace-level cytokines that affect the function of human pluripotent stem cell derived cardiomyocytes. DOI Europe PMC2 |
| 2023 | Perkins, G., Tunbridge, M., Chai, C. S., Hope, C., Yeow, A. E. L., Salehi, T., . . . Coates, T. (2023). mTOR inhibition improves the formation of functional T cell memory following COVID-19 vaccination of kidney transplant recipients. DOI Europe PMC2 |
| 2023 | Perkins, G., Hope, C., Chai, C. S., Tunbridge, M., Sterling, S., Webb, K., . . . Hissaria, P. (2023). Immune profiling of COVID-19 vaccine responses in people with multiple sclerosis on B cell-depleting therapy. DOI |
| 2021 | Adhikari, A., Abayasingam, A., Rodrigo, C., Agapiou, D., Pandzic, E., Brasher, N., . . . Tedla, N. (2021). Longitudinal characterisation of phagocytic and neutralisation functions of anti-Spike antibodies in plasma of patients after SARS-CoV-2 infection. DOI |
| 2021 | Ryan, F., Hope, C., Masavuli, M., Lynn, M., Mekonnen, Z., Lip Yeow, A. E., . . . Lynn, D. (2021). Long-term perturbation of the peripheral immune system months after SARS-CoV-2 infection. DOI Europe PMC1 |
| 2020 | Bull, R., Abayasingam, A., Balachandran, H., Agapiou, D., Rodrigo, C., Keoshkerian, E., . . . Martinello, M. (2020). Long-term persistence of neutralizing memory B cells in SARS-CoV-2. DOI |
2019 B Grubor-Bauk, EJ Gowans, DK Wijesundara ($200,000) "A novel Zika virus DNA vaccine that provides complete protection from infection." Commercial Accelerator Scheme, Adelaide Enterprise, University of Adelaide and The Hospital Research Foundation
2019 B Grubor-Bauk "Barbara Kidman Women's Fellowship" ($60,000). University of Adelaide and The Hospital Research Foundation
2019 DK Wijesundara, EJ Gowans, S Robertson, B Grubor-Bauk, A Shrestha "A pre-clinical evaluation of an innovative DNA-based vaccination regimen to protect women of childbearing age against Zika virus during sexual transmission." Ch7 Children's Research Foundation and The Hospital Research Foundation ($200,000)
2018 Z Kopecki, B Grubor-Bauk, KA Fenix, D Wijesundara, A Cowin ($28,619) "Identification of a diagnostic marker for assessment and management of psoriasis. New Adventures Fund UniSA and The Hospital Research Foundation
2018 EJ Gowans, B Grubor-Bauk, D Wijesundara, N Eyre ($88,000) "HCV challenge studies in vaccinated mice’ . Australian Centre for HIV and Hepatitis Virology Research (ACH2).
2016-2018 EJ Gowans, B Grubor-Bauk, D Wijesundara. ($293,880): A DNA vaccine for Zika virus. National Foundation for Medical Research and Innovation (NFMRI)
2017 EJ Gowans, B Grubor-Bauk, D Wijesundara ($85,000) A multigenotypic HCV DNA Vaccine. Australian Centre for HIV and Hepatitis Virology Research (ACH2)
2016-2017 EJ Gowans, B Grubor-Bauk, D Wijesundara ($100,000) "A DNA vaccine to induce protective neutralizing antibodies to the HIV Tat protein." The Hospital Research Foundation
2014 EJ Gowans, B Grubor-Bauk ($100,000) "Optimisation of HCV vaccine design." The Hospital Research Foundation .
2014-2015 EJ Gowans, I Roberts-Thomson, B Grubor-Bauk ($300, 000). “DNA vaccine therapy for HCV.” The Hospital Research Foundation .
2012-2013 E.J. Gowans and B Grubor-Bauk 2012/2013 ($174,000) “Development of a cytolytic HCV vaccine and a novel challenge model to test efficacy.” Australian Centre for HIV and Hepatitis Virology Research (ACH2).
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2024 | Principal Supervisor | Harnessing the potential of mRNA vaccines against Hepatitis C Virus | Doctor of Philosophy | Doctorate | Full Time | Mr John Henrik Johansson |
| 2024 | Principal Supervisor | Harnessing the potential of mRNA vaccines against Hepatitis C Virus | Doctor of Philosophy | Doctorate | Full Time | Mr John Henrik Johansson |
| 2023 | Co-Supervisor | The Effect of Sirolimus on Enhancing COVID-19 Vaccine Response in Transplant Recipients | Doctor of Philosophy | Doctorate | Full Time | Mr Cheng Sheng Chai |
| 2023 | Co-Supervisor | The Effect of Sirolimus on Enhancing COVID-19 Vaccine Response in Transplant Recipients | Doctor of Philosophy | Doctorate | Full Time | Mr Cheng Sheng Chai |
| 2022 | Principal Supervisor | A Trivalent Vaccine for Clinically-Important Flaviviruses. | Doctor of Philosophy | Doctorate | Full Time | Mr Ryan Santos |
| 2022 | Principal Supervisor | A Trivalent Vaccine for Clinically-Important Flaviviruses. | Doctor of Philosophy | Doctorate | Full Time | Mr Ryan Santos |
| 2021 | Principal Supervisor | The development of 'next generation' DNA-based vaccine against SARS-CoV-2 | Doctor of Philosophy | Doctorate | Full Time | Miss Zahraa Nima Saeed Al-Delfi |
| 2021 | Principal Supervisor | The development of 'next generation' DNA-based vaccine against SARS-CoV-2 | Doctor of Philosophy | Doctorate | Full Time | Miss Zahraa Nima Saeed Al-Delfi |
| 2021 | External Supervisor | Design of Lipid Nanoparticles (LNPs) for mRNA-Based Cancer Vaccines | Doctor of Philosophy | Doctorate | Part Time | Ms Mitra Hosseini Kharat |
| Date | Role | Research Topic | Program | Degree Type | Student Load | Student Name |
|---|---|---|---|---|---|---|
| 2015 - 2016 | Co-Supervisor | Strategies for the development of recombinant porcine adenovirus-based vaccines against Hepatitis C virus. | Master of Philosophy (Medical Science) | Master | Full Time | Mr Harshwardhan Jagdale |
| 2015 - 2019 | Co-Supervisor | Pre-Clinical Evaluation of a Vaccination Strategy to Induce Liver Resident Memory T Cells against Hepatitis C Virus | Doctor of Philosophy | Doctorate | Full Time | Mr Zelalem Addis Mekonnen |
| 2014 - 2018 | Co-Supervisor | Novel DNA Vaccine Formulations Against Hepatitis C Virus | Doctor of Philosophy | Doctorate | Full Time | Dr Makutiro Ghislain Masavuli |
| 2013 - 2016 | Co-Supervisor | Novel Recombinant DNA and Live Virus Vaccines to Prevent or Control HIV-1 Infection | Doctor of Philosophy | Doctorate | Full Time | Mr Khamis Tomusange |
| 2012 - 2014 | Co-Supervisor | Evaluating the Immuno-modulatory Effects of a Natural Adjuvant as a Novel Vaccine Strategy | Doctor of Philosophy | Doctorate | Full Time | Miss Tasmin Garrod |
| 2012 - 2013 | Co-Supervisor | Optimising DNA vaccine technology to prevent HIV-1 Infection | Doctor of Philosophy | Doctorate | Full Time | Miss Tessa Gargett |
| 2012 - 2017 | Co-Supervisor | The Development of a Multi-Antigenic Cytolytic DNA Vaccine against HCV | Doctor of Philosophy | Doctorate | Full Time | Dr Jason Anthony Gummow |
| 2010 - 2012 | Co-Supervisor | Suicide Genes in a Novel Vaccination Strategy for Hepatitis C | Master of Philosophy | Master | Full Time | Mr Hugh Francis Trahair |