William Hague

Research Interests

Pregnancy and Birth Translational Health Outcomes

Prof William Hague

School of Medicine

College of Health

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.

Professor Bill HagueMade in China, produced in Hong Kong and brought up in the UK, Bill Hague came to Adelaide, South Australia in 1988 as a Consultant and Research Fellow/Honorary Senior Lecturer, first at The Queen Elizabeth Hospital and later moving to the Women's and Children's Hospital in 1990. After undergraduate training at Trinity College, Cambridge and St Thomas' Hospital, London, he had completed his postgraduate training in Cambridge, Sheffield and London, in particular with Professor Michael de Swiet at Queen Charlotte's Hospital, London, and with Professor Howard Jacobs at the Middlesex Hospital, London, with specialist qualifications in both Internal Medicine and Obstetrics and Gynaecology, and with a Cambridge MD in Familial Aspects of Polycystic Ovaries. The obstetric medicine service he helped to build up at TQEH, and later at the W&CH, was recognised around Australia and overseas for its quality and commitment. His clinical service work, teaching and research achievements were recognised by The University of Adelaide with a promotion to full Professor in November 2011. He founded the Obstetric Medicine Group of Australasia (OMGA) in 1992, and in 2009 became the first Honorary Member of the Society of Obstetric Medicine of Australia and New Zealand (SOMANZ), following the amalgamation of OMGA and the Australasian Society for the Study of Hypertension in Pregnancy (ASSHP), of which he is a former President. His contributions include the first robust demonstration of the efficacy and safety of metformin in women with gestational diabetes (the MiG Study) in collaboration with Dr Janet Rowan from Auckland, published in the NEJM in 2008, and leading the writing of the SOMANZ consensus statement for the diagnosis and management of Intrahepatic cholestasis of pregnancy (ICP) in 2023. He has also been involved in the Australasian Maternity Outcomes Surveillance System (AMOSS).He retired from his position as Senior Consultant Physician in Obstetric Medicine, Women & Children's Hospital, Adelaide, in 2021, but continues as a Research Leader in Obstetric Medicine at the Robinson Research Institute, The University of Adelaide.Other Appointments◾Former Chair of the South Australian Maternal Mortality Committee◾Previous Member of the Australian National Advisory Committee on Maternal Mortality and Serious Morbidity◾South Australian Coordinator, Australasian Maternity Outcomes Surveillance System (AMOSS)◾Former Regional Secretary Oceania Region, International Christian Medical and Dental Association◾Former Oceania Desk-holder, Partners in International Medical Education◾Past National Chairman of the Christian Medical and Dental Fellowship of Australia◾Past Member of Advisory Council for South Australian Stillbirth and Neonatal Death Support GroupQualifications◾2001 FRCP (London) ◾1993 FRCOG◾1988 MD (Cantab)◾1987 Certificate of Accreditation (JCHMT), Endocrinology and Obstetric Medicine◾1983 MRCOG◾1978 MRCP(UK)◾1975 MA (Cantab)◾1975 MB, BChir (Cantab)◾1972 BA (Cantab)Research Interests◾The benefits of the diagnosis and management of early gestational diabetes in women at risk : the TOBOGM RCT◾Follow-up of offspring of women with eGDM in the TOBOGM RCT ; The TOMTHUMB study◾The comparison of pregnancy and health economic outcomes in women diagnosed as gestational diabetes (GDM) using ADIPS-1998 criteria compared with those diagnosed using IADPSG criteria◾The comparison of pregnancy and health economic outcomes in women diagnosed as GDM randomised to "tight" and "very tight" glucose control◾The prevalence of MODY genotypes in South Australian women with GDM◾Metformin as an alternative to insulin in the management of women with GDM : the MiG RCT◾Follow-up of offspring of women with GDM treated with metformin or insulin ; The MiG-TOFU study◾Metformin in the prevention of recurrent GDM◾Metformin effects on insulin resistance in women with GDM◾Metformin effects on vitamin B12 metabolism in women with GDM◾Pharmacokinetics of metformin in women with GDM◾Metformin for women who are obese during pregnancy for improving maternal and infant outcomes : the GROW RCT◾Postpartum SMS reminders to women who have had GDM to test for type 2 diabetes: a randomised controlled trial: The DIAMIND study ◾The place of low molecular weight heparin in the prevention of recurrent utero-placental thrombosis and associated diseases in women with thrombophilia : the TIPPS and FRUIT RCTs◾The role of genetic and acquired thrombophilia, including polymorphisms of methylenetetrahydrofolate reductase, activated protein C resistance, prothrombin gene mutation, protein S deficiency, hyperhomocysteinaemia and antiphospholipid antibodies in the aetiology of pre-eclampsia, placental abruption, intra-uterine growth restriction and recurrent miscarriage◾The role of genetic thrombophilia, including polymorphisms of methylenetetrahydrofolate reductase, activated protein C resistance and the prothrombin gene mutation in the aetiology of cerebral palsy◾The relationship of pre-eclampsia to the subsequent development of vascular disease and its link to hyperhomocysteinaemia◾The effect of folate supplementation on the prevention of pre-eclampsia: the Folic Acid Clinical Trial (FACT) RCT◾Follow-up of offspring of women treated with high dose folic acid compared with normal controls : the FACT for CHILD study◾Investigations in the Folic Acid Clinical Trial - the INFACT study◾The effect of folate supplementation on the prevention of recurrent pre-eclampsia in women with hyperhomocysteinaemia : the HOPE study◾Longitudinal study of genome stability in the mother, fetus, neonate and child in relation to folate and B12 status◾The role of common polymorphisms in the methylenetetrahydrofolate reductase, methionine synthase and thymidylate synthase genes as determinants of genome stability in mothers, fetuses, neonates and children◾The diagnosis and treatment of severe early onset intrahepatic cholestasis of pregnancy (ICP) : the TURRIFIC RCT◾The prevalence of ICP in South Australia◾Treatment of obstetric cholestasis: the PITCH RCT◾Genetic mechanisms of bile transporters◾The aetiology of microvesicular hepatic steatosis and its relationship to clinical outcomes in women and sheep◾The total Bile Acid Comparison and Harmonisation (BACH) project: a sub-study of the TURRIFIC RCT◾The potential value of extra-cellular vesicles to assess cholestasis in pregnancy◾The exploration of the gut microbiome in the aetiology of ICP◾The long-term outcome of the offspring of women who have had ICP using linkage studies◾The control of hypertension in pregnancy: the CHIPS RCT◾Follow-up of the offspring of the CHIPS study: the CHIPS-CHILD study◾The Australasian Maternity Outcomes Surveillance System (AMOSS)

Date Position Institution name
2012 - ongoing Professor University of Adelaide

Year Citation
2025 Hague, W. (2025). Barry Normand John Walters, FRACP, FRANZCOG ad eundem (1950–2024). Obstetric Medicine, 18(3), 200.
DOI
2025 Joglekar, M. V., Wong, W. K. M., Kunte, P. S., Hardikar, H. P., Kulkarni, R. A., Ahmed, I., . . . Hardikar, A. A. (2025). A microRNA-based dynamic risk score for type 1 diabetes. Nature Medicine, 31(8), 2622-2631.
DOI Scopus6 WoS6 Europe PMC5
2025 Ghiasi, M., Zwaigenbaum, L., Moddemann, D., White, R. R., Dingwall-Harvey, A. L. J., Grattan, K. P., . . . Walker, M. C. (2025). Follow-Up of Children Born to Mothers in Folic Acid Clinical Trial (FACT 4 Child): A Prospective Cohort Study Based on a Double-Blinded Randomised Controlled Trial.. BJOG: An International Journal of Obstetrics and Gynaecology, 1-10.
DOI Scopus1 WoS1
2025 Simmons, D., Immanuel, J., Hague, W. M., Coat, S., Teede, H., Nolan, C. J., . . . Cheung, N. W. (2025). Effect of treatment for early gestational diabetes mellitus on neonatal respiratory distress: A secondary analysis of the TOBOGM study. BJOG: an International Journal of Obstetrics and Gynaecology, 132(8), 1087-1095.
DOI Scopus8 WoS7 Europe PMC8
2025 Yuen, L., Wong, V., Immanuel, J., Hague, W. M., Cheung, N. W., Teede, H., . . . TOBOGM consortium. (2025). Ethnic Differences in Characteristics of Women Diagnosed with Early Gestational Diabetes: Findings from the TOBOGM Study. Journal of Clinical Endocrinology and Metabolism, 110(8), e2471-e2484.
DOI Scopus4 WoS4 Europe PMC6
2025 Jesudason, S., Safi, N., Li, Z., Brown, M., Hague, W., Makris, A., . . . Sullivan, E. (2025). Significant kidney disease in pregnancy: Feasibility and outcomes of a national population-based study using the Australasian Maternity Outcomes Surveillance System. Australian and New Zealand Journal of Obstetrics and Gynaecology, 65(2), 227-234.
DOI Scopus2 WoS2 Europe PMC1
2024 Hague, W. M. B. (2024). Hanns-Ulrich Marschall (15.2.1954-1.8.2023). Obstetric Medicine, 17(3), 137.
DOI
2024 Cheung, N. W., Rhou, Y. J. J., Immanuel, J., Hague, W. M., Teede, H., Nolan, C. J., . . . Simmons, D. (2024). Postpartum dysglycaemia after early gestational diabetes: Follow-up of women in the TOBOGM randomised controlled trial. Diabetes Research and Clinical Practice, 218, 111929-1-111929-6.
DOI Scopus3 WoS4 Europe PMC3
2024 Immanuel, J., Cheung, N. W., Mohajeri, M., Simmons, D. J., Hague, W. M., Teede, H., . . . TOBOGM Research Group. (2024). Association Between Glycemia, Glycemic Variability, and Pregnancy Complications in Early GDM. Diabetes Care, 48(2), 285-291.
DOI Scopus5 WoS4 Europe PMC3
2024 Seifu, C. N., Immanuel, J., Hague, W. M., Teede, H., Cheung, N. W., Hibbert, E. J., . . . TOBOGM Research Group. (2024). Association Between Immediate Treatment of Early Gestational Diabetes Mellitus and Breastfeeding Outcomes: Findings From the TOBOGM Study. Diabetes Care, 47(12), e99-e101.
DOI Scopus9 WoS9 Europe PMC8
2024 Simmons, D., Immanuel, J., Hague, W. M., Teede, H., Nolan, C. J., Peek, M. J., . . . TOBOGM Research Group. (2024). Perinatal Outcomes in Early and Late Gestational Diabetes Mellitus After Treatment From 24-28 Weeks' Gestation: A TOBOGM Secondary Analysis. Diabetes Care, 47(12), 2093-2101.
DOI Scopus17 WoS14 Europe PMC10
2024 Simmons, D., Immanuel, J., Hague, W. M., Teede, H., Nolan, C. J., Peek, M. J., . . . TOBOGM Research Group. (2024). Regression From Early GDM to Normal Glucose Tolerance and Adverse Pregnancy Outcomes in the Treatment of Booking Gestational Diabetes Mellitus Study. Diabetes Care, 47(12), 2079-2084.
DOI Scopus11 WoS9 Europe PMC6
2024 Haque, M. M., Tannous, W. K., Herman, W. H., Immanuel, J., Hague, W. M., Teede, H., . . . Simmons, D. (2024). Cost-effectiveness of diagnosis and treatment of early gestational diabetes mellitus: economic evaluation of the TOBOGM study, an international multicenter randomized controlled trial. eClinicalMedicine, 71, 102610-1-102610-11.
DOI Scopus20 WoS18 Europe PMC18
2024 Giles, S. K., Hague, W. M., & Edwards, R. A. (2024). ICP - could there be a virus in the works?. Obstetric Medicine, 17(3), 175-178.
DOI
2024 Sweeting, A., Enticott, J., Immanuel, J., Hague, W. M., Teede, H., Nolan, C. J., . . . TOBOGM Research Group. (2024). Relationship Between Early-Pregnancy Glycemia and Adverse Outcomes: Findings From the TOBOGM Study. Diabetes Care, 47(12), 2085-2092.
DOI Scopus10 WoS10 Europe PMC7
2024 Markus, C., & Hague, W. B. (2024). Measuring bile acids: Are we all talking the same language?. Obstetric Medicine, 17(3), 162-167.
DOI
2024 Hague, W. B., Williamson, C., & Beuers, U. (2024). Intrahepatic cholestasis of pregnancy: Introduction and overview 2024. Obstetric Medicine, 17(3), 138-143.
DOI Scopus2 WoS3 Europe PMC3
2023 Leggett, C., Ritchie, U., Costi, L., Borg, C., Elliot, D., Mangoni, A. A., & Hague, W. M. (2023). Response to Dr. Anderson's Letter to the Editor: Modafinil and Armodafinil in Human Milk. J Hum Lact, 39(2), 224-225.
DOI
2023 Simmons, D., Immanuel, J., Hague, W. M., Teede, H., Nolan, C. J., Peek, M. J., . . . TOBOGM Research Group. (2023). Treatment of Gestational Diabetes Mellitus Diagnosed Early in Pregnancy. New England Journal of Medicine, 388(23), 2132-2144.
DOI Scopus238 WoS220 Europe PMC191
2023 Reyes, P. A., Immanuel, J., Hague, W. M., Teede, H., Hibbert, E., Nolan, C. J., . . . Simmons, D. (2023). The relationship between body mass index and sleep in women with risk factors for gestational diabetes mellitus. Obesity Science and Practice, 9(6), 573-580.
DOI Scopus1 WoS1 Europe PMC2
2023 Hague, W. M., Briley, A., Callaway, L., Dekker Nitert, M., Gehlert, J., Graham, D., . . . Waugh, J. (2023). Intrahepatic cholestasis of pregnancy - Diagnosis and management: A consensus statement of the Society of Obstetric Medicine of Australia and New Zealand (SOMANZ): Executive summary. Australian and New Zealand Journal of Obstetrics and Gynaecology, 63(5), 656-665.
DOI Scopus16 WoS16 Europe PMC14
2023 Simmons, D., Immanuel, J., Hague, W. M., Teede, H., Nolan, C. J., Peek, M. J., . . . Cheung, N. W. (2023). Treatment of Gestational Diabetes Mellitus Diagnosed Early in Pregnancy. Obstetrical and Gynecological Survey, 78(11), 636-637.
DOI
2023 Markus, C., Coat, S., Marschall, H. -U., Matthews, S., Loh, T. P., Rankin, W., & Hague, W. M. (2023). Lot-to-lot reagent changes and commutability of quality testing materials for total bile acid measurements. Clinical Chemistry and Laboratory Medicine, 61(7), e108-e111.
DOI Scopus2 WoS1 Europe PMC1
2023 Khong, T. Y., Gordijn, S. J., Schoots, M. H., Ganzevoort, W., Groom, K. M., Coat, S., & Hague, W. M. (2023). Real-world experience of adding placental histopathology studies into perinatal clinical trials. Placenta, 136, 26-28.
DOI Scopus3 WoS3 Europe PMC3
2022 Ovadia, C., Mitchell, A. L., Markus, C., Hague, W. M., & Williamson, C. (2022). Bile acid reference intervals for evidence-based practice.. BJOG: an International Journal of Obstetrics and Gynaecology, 129(11), 1897-1898.
DOI
2022 Markus, C., Tan, R. Z., Lim, C. Y., Rankin, W., Matthews, S. J., Loh, T. P., & Hague, W. M. (2022). Performance of four regression frameworks with varying precision profiles in simulated reference material commutability assessment. Clinical Chemistry and Laboratory Medicine, 60(8), 1164-1174.
DOI Scopus1 WoS1 Europe PMC1
2022 Dixon, P. H., Levine, A. P., Cebola, I., Chan, M. M. Y., Amin, A. S., Aich, A., . . . Williamson, C. (2022). GWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements.. Nature Communications, 13(1), 4840-1-4840-18.
DOI Scopus34 WoS32 Europe PMC27
2022 Leggett, C., Ritchie, U., Costi, L., Elliot, D., Mangoni, A. A., & Hague, W. M. (2022). Infant Exposure to Armodafinil Through Human Milk Following Maternal Use of Modafinil. Journal of Human Lactation, 39(2), 218-222.
DOI Scopus3 WoS2 Europe PMC2
2021 Hague, W. M., Callaway, L., Chambers, J., Chappell, L., Coat, S., de Haan-Jebbink, J., . . . Williamson, C. (2021). A multi-centre, open label, randomised, parallel-group, superiority Trial to compare the efficacy of URsodeoxycholic acid with RIFampicin in the management of women with severe early onset Intrahepatic Cholestasis of pregnancy: the TURRIFIC randomised trial. BMC Pregnancy and Childbirth, 21(1), 51-1-51-14.
DOI Scopus41 WoS37 Europe PMC28
2021 Van Dam, J. M., Goldsworthy, M. R., Hague, W. M., Coat, S., & Pitcher, J. B. (2021). Cortical Plasticity and Interneuron Recruitment in Adolescents Born to Women with Gestational Diabetes Mellitus. Brain Sciences, 11(3), 388-1-388-12.
DOI Scopus3 WoS3 Europe PMC2
2021 Versace, V. L., Beks, H., Wesley, H., McNamara, K., Hague, W., Anjana, R. M., . . . Dunbar, J. A. (2021). Metformin for preventing type 2 diabetes mellitus in women with a previous diagnosis of gestational diabetes: a narrative review. Seminars in Reproductive Medicine, 38(6), 366-376.
DOI Scopus4 WoS4 Europe PMC4
2021 Ovadia, C., Sajous, J., Seed, P. T., Patel, K., Williamson, N. J., Attilakos, G., . . . Williamson, C. (2021). Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis. The Lancet Gastroenterology and Hepatology, 6(7), 547-558.
DOI Scopus113 WoS21 Europe PMC81
2021 Markus, C., Coat, S., Marschall, H. -U., Williamson, C., Dixon, P., Fuller, M., . . . Hague, W. M. (2021). The BACH project protocol: an international multicentre total Bile Acid Comparison and Harmonisation project and sub-study of the TURRIFIC randomised trial.. Clinical chemistry and laboratory medicine, 59(12), 1921-1929.
DOI Scopus11 WoS9 Europe PMC7
2021 Ovadia, C., Sajous, J., Seed, P. T., Patel, K., Williamson, N. J., Attilakos, G., . . . Williamson, C. (2021). Ursodeoxycholic Acid in Intrahepatic Cholestasis of Pregnancy: A Systematic Review and Individual Participant Data Meta-analysis. Obstetrical and Gynecological Survey, 76(9), 521-523.
DOI
2020 Leggett, C., Lwin, E. M. P., Ritchie, U., Song, Y., Gerber, J. P., Turner, S., . . . Garg, S. (2020). Perindopril in Breast Milk and Determination of Breastfed Infant Exposure: A Prospective Observational Study. Drug Design, Development and Therapy, 14, 961-967.
DOI Scopus6 WoS5 Europe PMC5
2020 Thaventhiran, J. E. D., Lango Allen, H., Burren, O. S., Rae, W., Greene, D., Staples, E., . . . Bleda, M. (2020). Whole-genome sequencing of a sporadic primary immunodeficiency cohort. Nature, 583(7814), 90-95.
DOI Scopus180 Europe PMC154
2020 Thaventhiran, J. E. D., Lango Allen, H., Burren, O. S., Rae, W., Greene, D., Staples, E., . . . Bleda, M. (2020). Whole-genome sequencing of a sporadic primary immunodeficiency cohort. Nature, 583(7814), 90-95.
DOI Scopus180 Europe PMC154
2020 Mousa, A., Løvvik, T., Hilkka, I., Carlsen, S. M., Morin-Papunen, L., Tertti, K., . . . Teede, H. J. (2020). Metformin in Pregnancy Study (MiPS): protocol for a systematic review with individual patient data meta-analysis. BMJ Open, 10(5), e036981-1-e036981-8.
DOI Scopus11 WoS10 Europe PMC9
2020 Turro, E., Astle, W. J., Megy, K., Gräf, S., Greene, D., Shamardina, O., . . . Hague, W. (2020). Whole-genome sequencing of patients with rare diseases in a national health system. Nature, 583(7814), 96-126.
DOI Scopus425 Europe PMC393
2020 Thaventhiran, J., Lango Allen, H., Burren, O., Rae, W., Greene, D., Staples, E., . . . Bleda, M. (2020). Publisher Correction: Whole-genome sequencing of a sporadic primary immunodeficiency cohort (Nature, (2020), 583, 7814, (90-95), 10.1038/s41586-020-2265-1). Nature, 584(7819), E2.
DOI Scopus4 Europe PMC5
2020 Walker, K. F., Chappell, L. C., Hague, W. M., Middleton, P., & Thornton, J. G. (2020). Pharmacological interventions for treating intrahepatic cholestasis of pregnancy. Cochrane Database of Systematic Reviews, 2020(7), 82 pages.
DOI Scopus91 WoS89 Europe PMC53
2020 Simmons, D., Rudland, V. L., Wong, V., Flack, J., Mackie, A., Ross, G. P., . . . Cheung, N. W. (2020). Options for screening for gestational diabetes mellitus during the SARS-CoV-2 pandemic. Australian and New Zealand Journal of Obstetrics and Gynaecology, 60(5), 660-666.
DOI Scopus11 Europe PMC8
2019 Yeap, S. P., Harley, H., Thompson, R., Williamson, K. D., Bate, J., Sethna, F., . . . Hague, W. (2019). Biliary transporter gene mutations in severe intrahepatic cholestasis of pregnancy: Diagnostic and management implications. Journal of Gastroenterology and Hepatology (Australia), 34(2), 425-435.
DOI Scopus10 WoS9 Europe PMC6
2019 Dodd, J., Louise, J., Deussen, A., Grivell, R., Dekker, G., McPhee, A., & Hague, W. (2019). Effect of metformin in addition to dietary and lifestyle advice for pregnant women who are overweight or obese: the GRoW randomised, double-blind, placebo-controlled trial. The Lancet Diabetes & Endocrinology, 7(1), 15-24.
DOI Scopus87 WoS79 Europe PMC69
2019 Ovadia, C., Seed, P. T., Sklavounos, A., Geenes, V., Di Illio, C., Chambers, J., . . . Williamson, C. (2019). Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses. The Lancet, 393(10174), 899-909.
DOI Scopus419 WoS373 Europe PMC307
2019 Wen, S. W., White, R. R., Rybak, N., Gaudet, L. M., Robson, S., Hague, W., . . . Walker, M. C. (2019). Effect of high dose folic acid supplementation in pregnancy on pre-eclampsia (fact): Double blind, Phase III, randomised controlled, international, multicentre trial. Obstetrical and Gynecological Survey, 74(2), 68-70.
DOI Scopus1
2019 Safi, N., Sullivan, E., Li, Z., Brown, M., Hague, W., McDonald, S., . . . Jesudason, S. (2019). Serious kidney disease in pregnancy: An Australian national cohort study protocol. BMC Nephrology, 20(1), 230-1-230-7.
DOI Scopus12 WoS10 Europe PMC6
2019 Wei, W., Tuna, S., Keogh, M. J., Smith, K. R., Aitman, T. J., Beales, P. L., . . . Hague, W. (2019). Germline selection shapes human mitochondrial DNA diversity. SCIENCE, 364(6442), 12 pages.
DOI WoS154 Europe PMC175
2019 Ovadia, C., Seed, P. T., Sklavounos, A., Geenes, V., Di Illio, C., Chambers, J., . . . Williamson, C. (2019). Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: Results of aggregate and individual patient data meta-analyses. Obstetrical and Gynecological Survey, 74(7), 388-390.
DOI
2018 Lwin, E. M. P., Leggett, C., Ritchie, U., Gerber, C., Song, Y., Hague, W., . . . Garg, S. (2018). Transfer of rosuvastatin into breast milk: Liquid chromatography-mass spectrometry methodology and clinical recommendations. Drug Design, Development and Therapy, 12, 3645-3651.
DOI Scopus20 WoS18 Europe PMC15
2018 Rowan, J. A., Rush, E. C., Plank, L. D., Lu, J., Obolonkin, V., Coat, S., & Hague, W. M. (2018). Metformin in gestational diabetes: the offspring follow-up (MiG TOFU): body composition and metabolic outcomes at 7-9 years of age. Obstetrical and Gynecological Survey, 73(10), 565-567.
DOI Scopus4 WoS4
2018 Rowan, J., Rush, E., Plank, L., Lu, J., Obolonkin, V., Coat, S., & Hague, W. (2018). Metformin in gestational diabetes: the offspring follow-up (MiG TOFU): body composition and metabolic outcomes at 7-9 years of age. BMJ Open Diabetes Research & Care, 6(1), e000456-1-e000456-12.
DOI Scopus260 WoS219 Europe PMC171
2018 Van Dam, J., Garrett, A., Schneider, L., Hodyl, N., Goldsworthy, M., Coat, S., . . . Pitcher, J. (2018). Reduced Cortical Excitability, Neuroplasticity, and Salivary Cortisol in 11–13-Year-Old Children Born to Women with Gestational Diabetes Mellitus. EBioMedicine, 31, 143-149.
DOI Scopus37 WoS33 Europe PMC31
2018 Simmons, D., Hague, W. M., Teede, H. J., Cheung, N. W., Hibbert, E. J., Nolan, C. J., . . . Rajagopal, R. (2018). Hyperglycaemia in early pregnancy: the treatment of booking gestational diabetes mellitus (TOBOGM) study. A randomised controlled trial. The Medical journal of Australia, 209(9), 405.e1-405.e6.
DOI Scopus57 WoS53 Europe PMC43
2018 Lwin, E., Gerber, C., Leggett, C., Song, Y., Ritchie, U., Turner, S., . . . Garg, S. (2018). Estimation of Atenolol Transfer Into Milk and Infant Exposure During Its Use in Lactating Women. Journal of Human Lactation, 34(3), 592-599.
DOI Scopus9 WoS10 Europe PMC10
2018 Dodd, J. M., Grivell, R. M., Deussen, A. R., & Hague, W. M. (2018). Metformin for women who are overweight or obese during pregnancy for improving maternal and infant outcomes. Cochrane Database of Systematic Reviews, 2018(7), CD010564-1-CD010564-35.
DOI Scopus60 WoS46 Europe PMC33
2018 Wen, S., White, R., Rybak, N., Gaudet, L., Robson, S., Hague, W., . . . Walker, M. (2018). Effect of high dose folic acid supplementation in pregnancy on pre-eclampsia (FACT): Double blind, phase III, randomised controlled, international, multicentre trial. BMJ (Online), 362, 8 pages.
DOI Scopus97 WoS80 Europe PMC65
2017 Wouldes, T. A., Battin, M., Coat, S., Rush, E. C., Hague, W. M., & Rowan, J. A. (2017). Neurodevelopmental Outcome at 2 Years in Offspring of Women Randomised to Metformin or Insulin Treatment for Gestational Diabetes. Obstetrical and Gynecological Survey, 72(3), 149-151.
DOI Scopus2 WoS1
2017 Marathe, J. A., Lim, W. H., Metz, M. P., Scheil, W., Dekker, G. A., & Hague, W. M. (2017). A retrospective cohort review of intrahepatic cholestasis of pregnancy in a South Australian population. European Journal of Obstetrics Gynecology and Reproductive Biology, 218, 33-38.
DOI Scopus44 WoS43 Europe PMC33
2017 Tieu, J., Coat, S., Hague, W., Middleton, P., & Shepherd, E. (2017). Oral anti-diabetic agents for women with established diabetes/impaired glucose tolerance or previous gestational diabetes planning pregnancy, or pregnant women with pre-existing diabetes. Cochrane Database of Systematic Reviews, 2017(10), 1-82.
DOI Scopus22 WoS17 Europe PMC7
2017 Farrant, M., Williamson, K., Battin, M., Hague, W., & Rowan, J. (2017). The use of dextrose/insulin infusions during labour and delivery in women with gestational diabetes mellitus: Is there any point?. Australian and New Zealand Journal of Obstetrics and Gynaecology, 57(3), 378-380.
DOI Scopus4 WoS4 Europe PMC4
2017 Dass Singh, M., Fenech, M., Hague, W., Owens, J., Thomas, P., Hor, M., & Theodora, A. (2017). Infant birth outcomes are associated with DNA damage biomarkers as measured by the cytokinesis block micronucleus cytome assay: the DADHI study. Mutagenesis, 32(3), 355-370.
DOI Scopus12 WoS13 Europe PMC9
2016 Vidler, M., Magee, L. A., von Dadelszen, P., Rey, E., Ross, S., Asztalos, E., . . . Trenowden, S. A. (2016). Women's views and postpartum follow-up in the CHIPS Trial (Control of Hypertension in Pregnancy Study). European Journal of Obstetrics Gynecology and Reproductive Biology, 206, 105-113.
DOI Scopus9 Europe PMC5
2016 Ahmed, R. J., Gafni, A., Hutton, E. K., Hu, Z. J., Pullenayegum, E., Von Dadelszen, P., . . . Magee, L. A. (2016). The Cost Implications of Less Tight Versus Tight Control of Hypertension in Pregnancy (CHIPS Trial). Hypertension, 68(4), 1049-1055.
DOI Scopus11 Europe PMC7
2016 Magee, L. A., Von Dadelszen, P., Singer, J., Lee, T., Rey, E., Ross, S., . . . Moutquin, J. M. (2016). The CHIPS randomized controlled trial (control of hypertension in pregnancy study). Hypertension, 68(5), 1153-1159.
DOI Scopus194 Europe PMC139
2016 Dodd, J. M., Grivell, R. M., Deussen, A. R., Dekker, G., Louise, J., & Hague, W. (2016). Metformin and dietary advice to improve insulin sensitivity and promote gestational restriction of weight among pregnant women who are overweight or obese: The GRoW randomised trial. BMC Pregnancy and Childbirth, 16(1), 359-1-359-7.
DOI Scopus7 WoS7 Europe PMC7
2016 Van Hoorn, M., Hague, W., Van Pampus, M., Bezemer, D., & De Vries, J. (2016). Low-molecular-weight heparin and aspirin in the prevention of recurrent early-onset pre-eclampsia in women with antiphospholipid antibodies: The FRUIT-RCT. European Journal of Obstetrics and Gynecology and Reproductive Biology, 197, 168-173.
DOI Scopus76 WoS69 Europe PMC55
2016 Voormolen, D., Abell, S., James, R., Hague, W., & Mol, B. (2016). Diagnostic criteria and treatment for gestational diabetes mellitus. Seminars in Reproductive Medicine, 34(2), 102-109.
DOI Scopus14 WoS11 Europe PMC7
2016 Wouldes, T., Battin, M., Coat, S., Rush, E., Hague, W., & Rowan, J. (2016). Neurodevelopmental outcome at 2 years in offspring of women randomised to metformin or insulin treatment for gestational diabetes. Archives of Disease in Childhood: Fetal and Neonatal Edition, 101(6), F488-F493.
DOI Scopus74 WoS55 Europe PMC54
2016 Abheiden, C. N. H., Van Hoorn, M. E., Hague, W. M., Kostense, P. J., Van Pampus, M. G., & De Vries, J. I. P. (2016). Authors' reply re: Does low-molecular-weight heparin influence fetal growth or uterine and umbilical arterial Doppler in women with a history of earlyonset uteroplacental insufficiency and an inheritable thrombophilia? Secondary randomised controlled trial results.. BJOG an International Journal of Obstetrics and Gynaecology, 123(5), 843.
DOI
2016 Abheiden, C., van Hoorn, M., Hague, W., Kostense, P., van Pampus, M., & de Vries, J. (2016). Authors' reply re: Does low-molecular-weight heparin influence fetal growth or uterine and umbilical arterial Doppler in women with a history of early-onset uteroplacental insufficiency and an inheritable thrombophilia? Secondary randomised controlled trial results. BJOG an International Journal of Obstetrics and Gynaecology, 123(5), 844-845.
DOI
2016 Abheiden, C. N. H., Van Hoorn, M. E., Hague, W. M., Kostense, P. J., van Pampus, M. G., & de Vries, J. I. P. (2016). Does low-molecular-weight heparin influence fetal growth and uterine and umbilical arterial flow-velocities in women with a history of early-onset utero-placental insufficiency and an inheritable thrombophilia? Secondary RCT results. BJOG: an International Journal of Obstetrics and Gynaecology, 123(5), 797-805.
DOI Scopus24 WoS20 Europe PMC14
2016 Van Ryswyk, E., Middleton, P., Hague, W., & Crowther, C. (2016). Women's views on postpartum testing for type 2 diabetes after gestational diabetes: Six month follow-up to the DIAMIND randomised controlled trial. Primary Care Diabetes, 10(2), 91-102.
DOI Scopus40 WoS32 Europe PMC27
2015 Geenes, V., Chambers, J., Khurana, R., Shemer, E., Sia, W., Mandair, D., . . . Williamson, C. (2015). Rifampicin in the treatment of severe intrahepatic cholestasis of pregnancy. European Journal of Obstetrics and Gynecology and Reproductive Biology, 189, 59-63.
DOI Scopus84 WoS74 Europe PMC58
2015 Geenes, V., Chambers, J., Khurana, R., Wikstrom-Shemer, E., Sia, W., Mandair, D., . . . Williamson, C. (2015). Rifampicin in the treatment of intrahepatic cholestasis of pregnancy. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 122, 1.
2015 Rodger, M. A., Hague, W. M., Kingdom, J., Kahn, S. R., Karovitch, A., Sermer, M., . . . Wells, P. S. (2015). Antepartum dalteparin versus no antepartum dalteparin for the prevention of pregnancy complications in pregnant women with thrombophilia (TIPPS): A multinational open-label randomised trial. Obstetrical and Gynecological Survey, 70(2), 76-78.
DOI
2015 Van Ryswyk, E., Middleton, P., Hague, W., & Crowther, C. (2015). Postpartum SMS reminders to women who have experienced gestational diabetes to test for Type 2 diabetes: the DIAMIND randomized trial. Diabetic Medicine, 32(10), 1368-1376.
DOI Scopus37 WoS38 Europe PMC31
2015 Battin, M., Obolonkin, V., Rush, E., Hague, W., Coat, S., & Rowan, J. (2015). Blood pressure measurement at two years in offspring of women randomized to a trial of metformin for GDM: follow up data from the MiG trial. BMC Pediatrics, 15(1), 54-1-54-5.
DOI Scopus33 WoS31 Europe PMC27
2015 Van Ryswyk, E., Middleton, P., Shute, E., Hague, W., & Crowther, C. (2015). Women's views and knowledge regarding healthcare seeking for gestational diabetes in the postpartum period: A systematic review of qualitative/survey studies. Diabetes Research and Clinical Practice, 110(2), 109-122.
DOI Scopus62 WoS62 Europe PMC55
2015 Singh, M., Thomas, P., Owens, J., Hague, W., & Fenech, M. (2015). Potential role of folate in pre-eclampsia. Nutrition Reviews, 73(10), 694-722.
DOI Scopus25 WoS19 Europe PMC17
2015 Rodger, M. A., Hague, W. M., Kingdom, J., Kahn, S. R., & Wells, P. S. (2015). Dalteparin for pregnant women with thrombophilia - Authors' reply. Lancet, 385(9969), 690.
DOI Scopus1 WoS1 Europe PMC1
2014 Rodger, M., Hague, W., Kingdom, J., Kahn, S., Karovitch, A., Sermer, M., . . . Wells, P. (2014). Antepartum dalteparin versus no antepartum dalteparin for the prevention of pregnancy complications in pregnant women with thrombophilia (TIPPS): a multinational open-label randomised trial. The Lancet, 384(9955), 1673-1683.
DOI Scopus211 WoS176 Europe PMC140
2014 Dorniak-Wall, T., Grivell, R., Dekker, G., Hague, W., & Dodd, J. (2014). The role of L-arginine in the prevention and treatment of pre-eclampsia: a systematic review of randomised trials. Journal of Human Hypertension, 28(4), 230-235.
DOI Scopus64 WoS61 Europe PMC44
2014 Van Ryswyk, E., Middleton, P., Hague, W., & Crowther, C. (2014). Clinician views and knowledge regarding healthcare provision in the postpartum period for women with recent gestational diabetes: a systematic review of qualitative/survey studies. Diabetes Research and Clinical Practice, 106(3), 401-411.
DOI Scopus44 WoS41 Europe PMC37
2014 Barrett, H., Nitert, M., McIntyre, H., Hague, W., Callaway, L., & Rowan, J. (2014). Predictors of preeclampsia in women in the Metformin in Gestational Diabetes(Mig) study. Journal of Diabetes & Metabolism, 5(7), 395-1-395-8.
DOI WoS3
2013 Eames, A., Grivell, R., Deussen, A., Hague, W., & Dodd, J. (2013). Metformin for women who are obese during pregnancy for improving maternal and infant outcomes. The Cochrane Database of Systematic Reviews, 2013(6), 1-9.
DOI Scopus11
2013 Gurung, V., Middleton, P., Milan, S., Hague, W., & Thornton, J. (2013). Interventions for treating cholestasis in pregnancy. The Cochrane Database of Systematic Reviews, 2013(6), 1-144.
DOI Scopus57 WoS78 Europe PMC42
2013 Barrett, H., Nitert, M., Jones, L., O'Rourke, P., Lust, K., Gatford, K., . . . Rowan, J. (2013). Determinants of maternal triglycerides in women with gestational diabetes mellitus in the Metformin in Gestational Diabetes (MiG) study. Diabetes Care, 36(7), 1941-1946.
DOI Scopus27 WoS24 Europe PMC15
2013 Gatford, K., Houda, C., Lu, Z., Coat, S., Baghurst, P., Owens, J., . . . Hague, W. (2013). Vitamin B12 and homocysteine status during pregnancy in the metformin in gestational diabetes trial: responses to maternal metformin compared with insulin treatment. Diabetes Obesity & Metabolism, 15(7), 660-667.
DOI Scopus24 WoS16 Europe PMC17
2013 Heatley, E., Middleton, P., Hague, W., & Crowther, C. (2013). The DIAMIND study: postpartum SMS reminders to women who have had gestational diabetes mellitus to test for type 2 diabetes: a randomised controlled trial - study protocol. BMC Pregnancy and Childbirth, 13(1), 1-6.
DOI Scopus44 WoS38 Europe PMC34
2013 Barrett, H., Gatford, K., Houda, C., De Blasio, M., McIntyre, H., Callaway, L., . . . Rowan, J. (2013). Maternal and neonatal circulating markers of metabolic and cardiovascular risk in the Metformin in Gestational Diabetes (MiG) trial: Responses to maternal metformin versus insulin treatment. Diabetes Care, 36(3), 529-536.
DOI Scopus41 WoS40 Europe PMC37
2013 Furness, D., Fenech, M., Dekker, G., Khong, T., Roberts, C., & Hague, W. (2013). Folate, Vitamin B12, Vitamin B6 and homocysteine: impact on pregnancy outcome. Maternal and Child Nutrition, 9(2), 155-166.
DOI Scopus88 WoS84 Europe PMC62
2012 de Vries, J., van Pampus, M., Hague, W., Bezemer, P., & Joosten, J. (2012). Low-molecular-weight heparin added to aspirin in the prevention of recurrent early-onset pre-eclampsia in women with inheritable thrombophilia: the FRUIT-RCT. Journal of Thrombosis and Haemostasis, 10(1), 64-72.
DOI Scopus154 WoS147 Europe PMC113
2012 Crowther, C., Hague, W., Middleton, P., Baghurst, P., McPhee, A., Tran, T., . . . Robinson, J. (2012). The IDEAL study: investigation of dietary advice and lifestyle for women with borderline gestational diabetes: a randomised controlled trial - study protocol. BMC Pregnancy and Childbirth, 12(106), 2-8.
DOI Scopus16 WoS15 Europe PMC8
2012 Rowan, J. A., Rush, E. C., Obolonkin, V., Battin, M., Wouldes, T., & Hague, W. M. (2012). Response to comments on: Rowan et al. Metformin in gestational diabetes: The offspring follow-up (MiG TOFU): Body composition at 2 years of age. Diabetes Care 2011;34:2279-2284. Diabetes Care, 35(3), e30.
DOI
2012 De Vries, J. I. P., Hague, W. M., & Van Pampus, M. G. (2012). Low-molecular-weight heparin added to aspirin in the prevention of recurrent early-onset pre-eclampsia in women with inheritable thrombophilia: the FRUIT-RCT: a reply to a rebuttal. Journal of Thrombosis and Haemostasis, 10(6), 1196.
DOI Scopus11 WoS2
2012 Gayford, K., McCarthy, A., & Hague, W. M. (2012). A case of postpartum Group B streptococcal meningitis. OBSTETRIC MEDICINE, 5(1), 25-26.
DOI WoS2 Europe PMC2
2011 Wickramasinghe, N., Troshani, I., Hill, S., Hague, W., & Goldberg, S. (2011). A transaction cost assessment of a pervasive technology solution for gestational diabetes. International Journal of Healthcare Information Systems and Informatics, 6(4), 60-76.
DOI Scopus15 WoS4
2011 de Vries, J. I., van Pampus, M. G., Hague, W. M., Bezemer, P. D., & Joosten, J. H. (2011). Fractionated Heparin in Pregnant Women with a History of Uteroplacental Insufficiency and Thrombophilia, a Randomized Trial (The FRUIT Study). REPRODUCTIVE SCIENCES, 18(3), 352A.
2011 Miragoli, M., Kadir, S., Sheppard, M., Salvarani, N., Virta, M., Wells, S., . . . Gorelik, J. (2011). A protective antiarrhythmic role of ursodeoxycholic acid in an in vitro rat model of the cholestatic fetal heart. Hepatology, 54(4), 1282-1292.
DOI Scopus82 WoS78 Europe PMC62
2011 Rowan, J., Rush, E., Obolonkin, V., Battin, M., Wouldes, T., & Hague, W. (2011). Metformin in gestational diabetes: The Offspring Follow-Up (MiG TOFU): body composition at 2 years of age. Diabetes Care, 34(10), 2279-2284.
DOI Scopus319 WoS261 Europe PMC204
2010 Rowan, J., Gao, W., Hague, W., & McIntyre, H. (2010). Glycemia and its relationship to outcomes in the metformin in Gestational Diabetes Trial. Diabetes Care, 33(1), 9-16.
DOI Scopus74 WoS67 Europe PMC63
2010 Furness, D., Dekker, G., Hague, W., Khong, T., & Fenech, M. (2010). Increased lymphocyte micronucleus frequency in early pregnancy is associated prospectively with pre-eclampsia and/or intrauterine growth restriction. Mutagenesis, 25(5), 489-498.
DOI Scopus50 WoS46 Europe PMC37
2010 Chittleborough, C., Baldock, K., Taylor, A., Hague, W., Willson, T., Martin, W., . . . Phillips, P. (2010). Long-term follow-up of women with gestational diabetes mellitus: The South Australian Gestational Diabetes Mellitus Recall Register. Australian & New Zealand Journal of Obstetrics & Gynaecology, 50(2), 127-131.
DOI Scopus27 WoS25 Europe PMC20
2010 Seppelt, I., Sullivan, E., Bellomo, R., Ellwood, D., Finfer, S., Howe, B., . . . Robinson, J. (2010). Critical illness due to 2009 A/H1N1 influenza in pregnant and postpartum women: population based cohort study. BMJ-BRITISH MEDICAL JOURNAL, 340(mar18 3), 6 pages.
DOI WoS134 Europe PMC157
2009 de Vries, J. I., Kist, W. J., & Hague, W. M. (2009). Confounded thrombophilia studies in preeclampsia. American Journal of Obstetrics and Gynecology, 201(5), e11-e12.
DOI
2009 Hague, W. (2009). Diabetes insipidus in pregnancy. Obstetric Medicine, 2(4), 138-141.
DOI WoS8 Europe PMC6
2009 Hotham, N., Ilett, K., Hackett, L., Morton, M., Muller, P., & Hague, W. (2009). Transfer of metyrapone and Its metabolite, rac-Metyrapol, into Breast milk. Journal of Human Lactation, 25(4), 451-454.
DOI Scopus8 WoS6 Europe PMC3
2009 Tieu, J., Coat, S., Hague, W., & Middleton, P. (2009). Oral anti-diabetic agents for women with pre-existing diabetes mellitus/impaired glucose tolerance or previous gestational diabetes mellitus. The Cochrane Database of Systematic Reviews, (2), 007724-1-007724-10.
DOI Scopus18 WoS12 Europe PMC11
2009 Hull, M., Nemeth, D., Hague, W., Wilkinson, C., Liebelt, J., Lane, M., & Inglis, D. (2009). Mitochondrial fatty acid transport enzyme deficiency-implications for in vitro fertilization. Fertility and Sterility, 91(6), 11-14.
DOI Scopus2 WoS2 Europe PMC1
2009 Djukic, M., Gibson, C., MacLennan, A., Goldwater, P., Haan, E., McMichael, G., . . . Casey, G. (2009). Genetic susceptibility to viral exposure may increase the risk of cerebral palsy. Australian & New Zealand Journal of Obstetrics & Gynaecology, 49(3), 247-253.
DOI Scopus30 WoS28 Europe PMC26
2008 Rodger, M., Paidas, M., McLintock, C., Middeldorp, S., Kahn, S., Martinelli, I., . . . Greer, I. (2008). Inherited thrombophilia and pregnancy complications revisited. Obstetrics and Gynecology, 112(2 Part 1), 320-324.
DOI Scopus114 WoS101 Europe PMC86
2008 van Gellekom, S., Lindauer-van der Werf, G., Hague, W., & de Vries, J. (2008). Anaemia and haemolysis in pregnancy due to rapid folic acid and vitamin B12 depletion. Netherlands Journal of Medicine, 66(5), 216-217.
Scopus3 WoS2 Europe PMC3
2008 Rowan, J., Hague, W., Gao, W., Battin, M., & Moore, M. (2008). Metformin versus insulin for the treatment of gestational diabetes. New England Journal of Medicine, 358(19), 2003-2016.
DOI Scopus997 WoS637 Europe PMC595
2008 Kist, W., Janssen, N., Kalk, J., Hague, W., Dekker, G., & de Vries, J. (2008). Thrombophilias and adverse pregnancy outcome - A confounded problem!. Thrombosis and Haemostasis, 99(1), 77-85.
DOI Scopus82 WoS72 Europe PMC52
2008 Rowan, J. A., Hague, W. M., Gao, W., Battin, M. R., & Moore, M. P. (2008). Metformin versus insulin for the treatment of gestational diabetes. Obstetrical and Gynecological Survey, 63(10), 616-618.
DOI Scopus3
2008 Rodger, M. A., Paidas, M., McLintock, C., Middeldorp, C., Kahn, S., Martinelli, I., . . . Greer, I. (2008). Erratum: Inherited thrombophilia and pregnancy complications revisited (Obstetrics & Gynecology (2008) 112 (320-324)). Obstetrics and Gynecology, 112(6), 1392.
DOI
2007 Moss, J., Crowther, C., Hiller, J., Willson, K., & Robinson, J. (2007). Costs and consequences of treatment for mild gestational diabetes mellitus - evaluation from the ACHOIS randomised trial. BMC Pregnancy and Childbirth, 7(27), 1-7.
DOI Scopus99 Europe PMC66
2007 Rodger, M., Kahn, S., Cranney, A., Hodsman, A., Kovacs, M., Clement, A., . . . Hague, W. (2007). Long-term dalteparin in pregnancy not associated with a decrease in bone mineral density: Substudy of a randomized controlled trial. Journal of Thrombosis and Haemostasis, 5(8), 1600-1606.
DOI Scopus85 WoS61 Europe PMC57
2007 Williams, V., Griffiths, A., Carbone, S., & Hague, W. (2007). Fibrinogen concentration and factor VIII activity in women with preeclampsia. Hypertension in Pregnancy, 26(4), 415-421.
DOI Scopus22 WoS22 Europe PMC20
2007 Hague, W. (2007). Metformin in pregnancy and lactation. Australian Prescriber, 30(3), 68-69.
DOI Scopus4 WoS2
2006 Rakhorst, A. C., Dekker, G. A., Erwich, J. J. H. M., & Hague, W. M. (2006). Patterns of risk factors for recurrent preeclampsia in women with a history of early-onset preeclampsia.. HYPERTENSION IN PREGNANCY, 25, 186.
2006 Williams, V. K., Griffiths, A. B. M., Carbone, S., & Hague, W. M. (2006). Fibrinogen concentration and Factor VIII activity in women with preeclampsia.. HYPERTENSION IN PREGNANCY, 25, 184.
2006 Gibson, C., MacLennan, A., Janssen, N., Kist, W., Hague, W., Haan, E., . . . Dekker, G. (2006). Associations between fetal inherited thrombophilia and adverse pregnancy outcomes. American Journal of Obstetrics and Gynecology, 194(4), 947e1-947e10.
DOI Scopus38 WoS26 Europe PMC19
2006 Gibson, C., MacLennan, A., Goldwater, P., Haan, E., Priest, K., Dekker, G., . . . Morton, M. (2006). The association between inherited cytokine polymorphisms and cerebral palsy. American Journal of Obstetrics and Gynecology, 194(3), 674e1-674e11.
DOI Scopus61 WoS39 Europe PMC37
2006 Charles, B., Norris, R., XIAO, X., & Hague, W. (2006). Population pharmacokinetics of metformin in late pregnancy. Therapeutic Drug Monitoring, 28(1), 67-72.
DOI Scopus185 WoS159 Europe PMC131
2005 Gibson, C., MacLennan, A., Hague, W., Haan, E., Priest, K., Chan, A., & Dekker, G. (2005). Associations between inherited thrombophilias, gestational age, and cerebral palsy. American Journal of Obstetrics and Gynecology, 193(4), 1437.e1-1437.e12.
DOI Scopus61 WoS43 Europe PMC35
2005 Ward, E., McIntyre, A., Van Kessel, G., & Hague, W. (2005). Immediate blood pressure changes and aquatic physiotherapy. Hypertension in Pregnancy, 24(2), 93-102.
DOI Scopus4 WoS3 Europe PMC2
2005 Gibson, C., MacLennan, A., Rudzki, Z., Hague, W., Haan, E., Sharpe, P., . . . Khong, T. (2005). The prevalence of inherited thrombophilias in a Caucasian Australian population. Pathology, 37(2), 160-163.
DOI Scopus27 WoS24 Europe PMC20
2004 Norman, R., Wang, J., & Hague, W. (2004). Should we continue or stop insulin sensitizing drugs during pregnancy?. Current Opinion in Obstetrics & Gynecology, 16(3), 245-250.
DOI Scopus51 WoS40 Europe PMC38
2003 Hague, W., Davoren, P., Oliver, J., & Rowan, J. (2003). Contraindications to use of metformin - Metformin may be useful in gestational diabetes. British Medical Journal, 326(7392), 762-763.
DOI Scopus33 WoS50 Europe PMC22
2003 Hague, W., & Dekker, G. (2003). Risk factors for thrombosis in pregnancy. Best Practice & Research Clinical Haematology, 16(2), 197-210.
DOI Scopus27 WoS15 Europe PMC15
2003 Hague, W. (2003). Homocysteine and pregnancy. Best Practice & Research in Clinical Obstetrics & Gynaecology, 17(3), 459-469.
DOI Scopus130 WoS119 Europe PMC89
2003 Elder, A. T., Hague, W. M., Davoren, P. M., Oliver, J., Rowan, J., Jones, P., . . . Jones, G. C. (2003). Contraindications to use of metformin. BMJ, 326(7392), 762.
DOI Scopus42 Europe PMC8
2002 Hague, W. (2002). Cardiac intraventricular thrombus in protein C deficiency. Journal of the Royal Society of Medicine, 95(8), 426.
DOI
2002 Brink, A., Akande, W., Moodley, J., Hague, W., Hall, D., Steyn, W., . . . Odendaal, H. (2002). Hypertension in pregnancy : round-table discussion: part 1: cardiovascular profile. Cardiovascular Journal of South Africa, 13(1), 22-28.
2002 Brink, A., Akande, W., Moodley, J., Hague, W., Hall, D., Steyn, W., . . . Odendaal, H. (2002). Hypertension in pregnancy: Round-table discussion: Part I. Cardiovascular Journal of South Africa, 13(1), 22-28.
2002 Brink, A., Akande, W., Moodley, J., Hague, W., Hall, D., Steyn, W., . . . Odendaal, H. (2002). Hypertension in pregnancy. Round-table discussion: Part 2. Cardiovascular Journal of South Africa, 13(2), 68-72.
Scopus2 Europe PMC2
2001 Khong, T. Y., Moore, L., & Hague, W. M. (2001). Thrombophilias and adverse pregnancy outcome (multiple letters). Human Reproduction, 16(2), 395-397.
DOI Scopus5 Europe PMC1
2001 Khong, T., Moore, L., & Hague, W. (2001). Thrombophilias and adverse pregnancy outcome. Human Reproduction, 16(2), 395-396.
DOI WoS2 Europe PMC4
2001 Hague, W., North, R., Gallus, A., Walters, B., Orlikowski, C., Burrows, R., . . . Peek, M. (2001). Anticoagulation in pregnancy and the puerperium. Medical Journal of Australia, 175(5), 258-263.
DOI Scopus37 WoS26 Europe PMC19
2001 Khong, T., & Hague, W. (2001). Biparental contribution to fetal thrombophilia in discordant twin intrauterine growth restriction. American Journal of Obstetrics and Gynecology, 185(1), 244-245.
DOI Scopus33 WoS26 Europe PMC30
2001 Hague, W. M. (2001). Endocrine disease (including diabetes). Best Practice and Research Clinical Obstetrics and Gynaecology, 15(6), 877-889.
DOI Scopus4 WoS3 Europe PMC1
2000 Crocker, H., Pfitzner, J., Doyle, I., Hague, W., Smith, B., & Ruffin, R. (2000). Pulmonary alveolar proteinosis: two contrasting cases. European Respiratory Journal, 15(2), 426-429.
DOI Scopus11 WoS9 Europe PMC7
2000 Brown, M. A., Hague, W. M., Higgins, J., Lowe, S., McCowan, L., Oats, J., . . . Walters, B. N. J. (2000). The detection, investigation and management of hypertension in pregnancy: Full consensus statement. Australian and New Zealand Journal of Obstetrics and Gynaecology, 40(2), 139-155.
DOI Scopus242 Europe PMC183
2000 Brown, M. A., Hague, W. M., Higgins, J., Lowe, S., McCowan, L., Oats, J., . . . Walters, B. N. J. (2000). The detection, investigation and management of hypertension in pregnancy: Executive summary. Australian and New Zealand Journal of Obstetrics and Gynaecology, 40(2), 133-138.
DOI Scopus192 Europe PMC123
1999 Hague, W. M. (1999). Pre-existing endocrine disease in relation to pregnancy. Current Obstetrics and Gynaecology, 9(2), 62-68.
DOI Scopus5
1999 Crowther, C., Hiller, J., Pridmore, B., Bryce, R., Duggan, P., Hague, W., & Robinson, J. (1999). Calcium supplementation in nulliparous women for the prevention of pregnancy-induced hypertension, preeclampsia and preterm birth: an Australian randomised trial. Australian and New Zealand Journal of Obstetrics and Gynaecology, 39(1), Dec-18.
DOI Scopus92 WoS84 Europe PMC71
1999 Khong, T., & Hague, W. (1999). The placenta in maternal hyperhomocysteinaeima. British Journal of Obstetrics and Gynaecology, 106(3), 273-278.
DOI Scopus61 WoS48 Europe PMC32
1998 Norman, R., Huber Buchholz, M. M., & Hague, W. (1998). Genetic and environmental origins of polycyctic ovary syndrome. Contemporary Reviews in Obstetrics and Gynecology, 10(6), 141-149.
1998 Terry, A., & Hague, W. (1998). Postpartum thyroiditis. Seminars in Perinatology, 22(6), 497-502.
DOI Scopus21 WoS8 Europe PMC5
1998 Hague, W. (1998). A practical approach to amenorrhoea. New Ethicals Journal, 1(12), 61-70.
1998 Norman, R., Huber-Buchholz, M., & Hague, W. (1998). Genetic and environmental origins of polycystic ovary syndrome. Contemporary Reviews in Obstetrics and Gynaecology, 10(2), 141-149.
Scopus2
1997 Hague, W. (1997). A practical approach to Amenorrhoea. Current Therapeutics, 38(5), 57-65.
1996 Norman, R., Masters, S., & Hague, W. (1996). Hyperinsulinemia is common in family members of women with polycystic ovary syndrome. Fertility and Sterility, 66(6), 942-947.
DOI Scopus119 WoS93 Europe PMC65
1995 Norman, R., Masters, S., Hague, W., Beng, C., Pannall, P., & Wang, J. (1995). Metabolic approaches to the subclassification of Polycystic Ovary Syndrome. Fertility and Sterility, 63(2), 329-335.
DOI Scopus82 WoS74 Europe PMC43
1995 Brennecke, S., Brown, M., Crowther, C., Hague, W., & King, J. (1995). Aspirin and prevention of preeclampsia. Australian and New Zealand Journal of Obstetrics and Gynaecology, 35(1), 38-41.
DOI
1995 Norman, R., Hague, W., Masters, S., & Wang, X. (1995). Subjects with polycystic ovaries without hyperandrogenaemia exhibit similar disturbances in insulin and lipid profiles as those with Polycystic Ovary Syndrome. Human Reproduction, 10(9), 2258-2261.
DOI Scopus78 WoS71 Europe PMC53
1994 BEROYZ, G., CASALE, R., FARREIROS, A., PALERMO, M., MARGULIES, M., VOTO, L., . . . FIDALGO, C. (1994). CLASP - A RANDOMIZED TRIAL OF LOW-DOSE ASPIRIN FOR THE PREVENTION AND TREATMENT OF PREECLAMPSIA AMONG 9364 PREGNANT-WOMEN. LANCET, 343(8898), 619-629.
DOI WoS722 Europe PMC137
1994 Kennedy, S., Hall, P. D. L. M., Seymour, A. E., & Hague, W. M. (1994). Transient diabetes insipidus and acute fatty liver of pregnancy. BJOG an International Journal of Obstetrics Gynaecology, 101(5), 387-391.
DOI Scopus91 Europe PMC36
1993 Slattery, M. A., Khang, T. Y., Dawkins, R. R., Pridmore, B. R., & Hague, W. M. (1993). Eclampsia in association with partial molar pregnancy and congenital abnormalities. American Journal of Obstetrics and Gynecology, 169(6), 1625-1627.
DOI Scopus16 Europe PMC4
1992 Hague, W. M. (1992). Premature menopause management.. Australian Family Physician, 21(3), 252-254.
1990 HAGUE, W. M., ADAMS, J., RODDA, C., BROOK, C. G. D., DE BRUYN, R., GRANT, D. B., & JACOBS, H. S. (1990). THE PREVALENCE OF POLYCYSTIC OVARIES IN PATIENTS WITH CONGENITAL ADRENAL HYPERPLASIA AND THEIR CLOSE RELATIVES. Clinical Endocrinology, 33(4), 501-510.
DOI Scopus152 Europe PMC109
1990 HAGUE, W. M., ADAMS, J., ALGAR, V., DRUMMOND, V., SCHWARZ, G., BOTTAZZO, G., & JACOBS, H. S. (1990). HLA ASSOCIATIONS IN PATIENTS WITH POLYCYSTIC OVARIES AND IN PATIENTS WITH CONGENITAL ADRENAL HYPERPLASIA CAUSED BY 21‐HYDROXYLASE DEFICIENCY. Clinical Endocrinology, 32(4), 407-416.
DOI Scopus21 Europe PMC10
1990 Hague, W. M., & Norman, R. J. (1990). Recent advances in understanding of normal hormone mechanisms of the female reproductive system. Current Opinion in Obstetrics and Gynecology, 2(3), 363-369.
1989 HAGUE, W. M., HONOUR, J. W., ADAMS, J., VECSEI, P., & JACOBS, H. S. (1989). STEROID RESPONSES TO ACTH IN WOMEN WITH POLYCYSTIC OVARIES. Clinical Endocrinology, 30(4), 355-365.
DOI Scopus35 Europe PMC20
1989 HAGUE, W. M., ADAMS, J., REEDERS, S. T., & JACOBS, H. S. (1989). 45 X Turner's syndrome in association with polycystic ovaries. Case report. BJOG an International Journal of Obstetrics Gynaecology, 96(5), 613-618.
DOI Scopus7 Europe PMC3
1988 LAW, A., HAGUE, W. M., DALY, J. G., HONOUR, J. W., TAYLOR, N., JEFFCOATE, S. L., . . . JOPLIN, G. F. (1988). INAPPROPRIATE ACTH CONCENTRATIONS IN TWO PATIENTS WITH FUNCTIONING ADRENOCORTICAL CARCINOMA. Clinical Endocrinology, 29(1), 53-62.
DOI Scopus3 Europe PMC2
1988 Rumsby, G., Fielder, A. H. L., Hague, W. M., & Honour, J. W. (1988). Heterogeneity in the gene locus for steroid 21-hydroxylase deficiency. Journal of Medical Genetics, 25(9), 596-599.
DOI Scopus11 Europe PMC7
1988 HAGUE, W. M., ADAMS, J., REEDERS, S. T., PETO, T. E. A., & JACOBS, H. S. (1988). FAMILIAL POLYCYSTIC OVARIES: A GENETIC DISEASE?. Clinical Endocrinology, 29(6), 593-605.
DOI Scopus163 Europe PMC101
1987 Hague, W. M. (1987). Treatment of endocrine diseases. British Medical Journal Clinical Research Ed, 294(6567), 297-300.
DOI Scopus1 Europe PMC1
1987 Hague, W. M., Tan, S. L., Adams, J., & Jacobs, H. S. (1987). Hypergonadotropic amenorrhea - etiology and outcome in 93 young women. International Journal of Gynecology and Obstetrics, 25(2), 121-125.
DOI Scopus16 Europe PMC8
1986 Hague, W. M., & de Swiet, M. (1986). A syndrome ot liver damage and intravascular coagulation in the last trimester of normotensive pregnancy. A clinical and histopathological study. BJOG an International Journal of Obstetrics Gynaecology, 93(10), 1113-1114.
DOI
1986 Tan, S. L., Hague, W. M., Becker, F., & Jacobs, H. S. (1986). Autoimmune premature ovarian failure with polyendocrinopathy and spontaneous recovery of ovarian follicular activity. Fertility and Sterility, 45(3), 421-424.
DOI Scopus20 Europe PMC12
1986 Chapman, M. G., Katz, M., Dowsett, M., Hague, W., Jeffcoate, S. L., & Dewhurst, C. J. (1986). Spironolactone in the Treatment of Hirsutism. Acta Obstetricia Et Gynecologica Scandinavica, 65(4), 349-350.
DOI Scopus8 Europe PMC5
1986 HAGUE, W. M., ABDULWAHID, N. A., JACOBS, H. S., & CRAFT, I. (1986). Use of LHRH analogue to obtain reversible castration in a patient with benign metastasizing leiomyoma. BJOG an International Journal of Obstetrics Gynaecology, 93(4), 455-460.
DOI Scopus52 Europe PMC28
1985 HAGUE, W. M., & MILLAR, D. R. (1985). Excessive testosterone secretion in pregnancy. Case report. BJOG an International Journal of Obstetrics Gynaecology, 92(2), 173-178.
DOI Scopus7 Europe PMC4
1984 SLATER, D. N., & HAGUE, W. M. (1984). Renal morphological changes in idiopathic acute fatty liver of pregnancy. Histopathology, 8(4), 567-581.
DOI Scopus30 Europe PMC15
1984 Hague, W., Wallace, R., Sims, C., & Gau, G. (1984). Placenta accreta in a uterus didelphys (bicollis). Journal of Obstetrics and Gynaecology, 5(2), 104-105.
1983 HAGUE, W. M., & HONOUR, J. W. (1983). MALIGNANT HYPERTENSION IN CONGENITAL ADRENAL HYPERPLASIA DUE TO 11β‐HYDROXYLASE DEFICIENCY. Clinical Endocrinology, 18(5), 505-510.
DOI Scopus32 Europe PMC20
1983 Hague, W. M., Duncan, S. L. B., Fenton, D. W., & Slater, D. N. (1983). Acute fatty liver of pregnancy. Journal of the Royal Society of Medicine, 76(8), 652-661.
DOI Scopus24 Europe PMC13
1982 HAGUE, W. M., MUNRO, D. S., SAWERS, R. S., DUNCAN, S. L. B., & HONOUR, J. W. (1982). Long‐term effects of cyproterone acetate on the pituitary adrenal axis in adult women. BJOG an International Journal of Obstetrics Gynaecology, 89(12), 981-984.
DOI Scopus8 Europe PMC10
1980 Hague, W. M. (1980). MEDIASTINAL AND SUBCUTANEOUS EMPHYSEMA IN A PREGNANT PATIENT WITH ASTHMA CASE REPORT. BJOG an International Journal of Obstetrics Gynaecology, 87(5), 440-443.
DOI Scopus7 Europe PMC3

Year Citation
2019 Hague, W. M., & Roberts-Thomson, I. C. (2019). Liver and Gastrointestinal Disorders During Pregnancy. In M. Wichmann, T. K. McCullough, I. C. Roberts-Thomson, & G. J. Maddern (Eds.), Gastroenterology For General Surgeons (pp. 237-243). Springer International Publishing.
DOI
2015 Henry, C., & Hague, W. M. (2015). Type 2 diabetes mellitus. In Case Studies in Assisted Reproduction Common and Uncommon Presentations (pp. 1-6). Cambridge University Press.
DOI
2015 Morton, M. R., & Hague, W. M. (2015). A woman with hypertension. In Case Studies in Assisted Reproduction Common and Uncommon Presentations (pp. 7-11). Cambridge University Press.
DOI Scopus1
2015 Clark, E., & Hague, W. M. (2015). A patient with severe lupus. In Case Studies in Assisted Reproduction Common and Uncommon Presentations (pp. 33-37). Cambridge University Press.
DOI
2015 Jesudason, S., & Hague, W. M. (2015). A woman with renal impairment. In Case Studies in Assisted Reproduction Common and Uncommon Presentations (pp. 19-23). Cambridge University Press.
DOI
2013 Wickramasinghe, N., Troshani, I., Hill, S. R., Hague, W., & Goldberg, S. (2013). A transaction cost assessment of a pervasive technology solution for gestational diabetes. In Healthcare Information Technology Innovation and Sustainability Frontiers and Adoption (pp. 109-126). IGI Global.
DOI Scopus5
2007 Hague, W. (2007). Effects of pregnancy on the endocrine system. In I. Greer, C. Nelson-Piercy, & B. Walters (Eds.), Maternal Medicine: Medical Problems in Pregnancy (pp. 70-73). UK: Churchill Livingstone.
2007 Hague, W. (2007). Parathyroid, Adrenal and Pituitary Disease in Pregnancy. In I. Greer, C. Nelson-Piercy, & B. Walters (Eds.), Maternal Medicine: Medical Problems in Pregnancy (pp. 78-82). UK.
1995 Hague, W. (1995). Treatment of endocrine diseases. In Prescribing in Pregnancy (pp. 85-96). British Medical Journal Publishing Group.

Year Citation
2017 Hodyl, N. A., Stark, M. J., Hague, W., Rowan, J. A., Coat, S., Teede, H., & Moran, L. J. (2017). The association between cord blood cardiometabolic and inflammatory markers and maternal PCOS status. Poster session presented at the meeting of CLINICAL ENDOCRINOLOGY. WILEY-BLACKWELL.
2014 Marathe, J., Lim, W., Dekker, G. A., & Hague, W. M. (2014). Gestational diabetes and obstetric cholestasis: a 10 year retrospective cohort review of outcomes and predictors. Poster session presented at the meeting of DIABETOLOGIA. SPRINGER.
2013 Rodger, M., Hague, W. M., Kingdom, J., Kahn, S. R., Karovitch, A., Wells, P. S., . . . TIPPS Investigators. (2013). The Thrombophilia in Pregnancy Prophylaxis Study (TIPPS): a multi-national randomized trial of dalteparin vs. no dalteparin to prevent pregnancy complications in pregnant thrombophilic women. Poster session presented at the meeting of Abstracts of the 24th Congress of the International Society on Thrombosis and Haemostasis, as published in Journal of Thrombosis and Haemostasis. Amsterdam, The Netherlands: Wiley-Blackwell.
DOI WoS2
2013 Van Hoorn, M., Hague, W., Van Pampus, M., Bezemer, P., & De Vries, J. (2013). Low-molecular-weight heparin added to aspirin in the prevention of recurrent early-onset preeclampsia in women with antiphospholipid antibodies. Poster session presented at the meeting of Abstracts of the 24th Congress of the International Society on Thrombosis and Haemostasis, as published in Journal of Thrombosis and Haemostasis. Amsterdam, The Netherlands: Wiley-Blackwell.
DOI WoS1

Date Role Research Topic Program Degree Type Student Load Student Name
2012 - 2015 Co-Supervisor Improving Postpartum Healthcare and Health Outcomes of Women with a History Gestational Diabetes Mellitus Doctor of Philosophy Doctorate Full Time Dr Emer Van Ryswyk
2011 - 2017 Principal Supervisor Diet and DNA damage in infants The DADHI study Doctor of Philosophy Doctorate Full Time Dr Mansi Dass Singh
2005 - 2008 Co-Supervisor Genome Damage and Folate Nutrigenomics in Uteroplacental Insufficiency Doctor of Philosophy Doctorate Full Time Dr Denise Furness

Connect With Me

External Profiles

Other Links