Professor William Hague
Professor
Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.
Professor Bill Hague
Made in China, produced in Hong Kong and brought up in the UK, Bill Hague came to Adelaide, South Australia in 1988 as a Consultant and Research Fellow/Honorary Senior Lecturer, first at The Queen Elizabeth Hospital and later moving to the Women's and Children's Hospital in 1990. After undergraduate training at Trinity College, Cambridge and St Thomas' Hospital, London, he had completed his postgraduate training in Cambridge, Sheffield and London, in particular with Professor Michael de Swiet at Queen Charlotte's Hospital, London, and with Professor Howard Jacobs at the Middlesex Hospital, London, with specialist qualifications in both Internal Medicine and Obstetrics and Gynaecology, and with a Cambridge MD in Familial Aspects of Polycystic Ovaries. The obstetric medicine service he helped to build up at TQEH, and later at the W&CH, was recognised around Australia and overseas for its quality and commitment. His clinical service work, teaching and research achievements were recognised by The University of Adelaide with a promotion to full Professor in November 2011. He founded the Obstetric Medicine Group of Australasia (OMGA) in 1992, and in 2009 became the first Honorary Member of the Society of Obstetric Medicine of Australia and New Zealand (SOMANZ), following the amalgamation of OMGA and the Australasian Society for the Study of Hypertension in Pregnancy (ASSHP), of which he is a former President. His contributions include the first robust demonstration of the efficacy and safety of metformin in women with gestational diabetes (the MiG Study) in collaboration with Dr Janet Rowan from Auckland, published in the NEJM in 2008, and leading the writing of the SOMANZ consensus statement for the diagnosis and management of Intrahepatic cholestasis of pregnancy (ICP) in 2023. He has also been involved in the Australasian Maternity Outcomes Surveillance System (AMOSS).
He retired from his position as Senior Consultant Physician in Obstetric Medicine, Women & Children's Hospital, Adelaide, in 2021, but continues as a Research Leader in Obstetric Medicine at the Robinson Research Institute, The University of Adelaide.
Other Appointments
◾Former Chair of the South Australian Maternal Mortality Committee
◾Previous Member of the Australian National Advisory Committee on Maternal Mortality and Serious Morbidity
◾South Australian Coordinator, Australasian Maternity Outcomes Surveillance System (AMOSS)
◾Former Regional Secretary Oceania Region, International Christian Medical and Dental Association
◾Former Oceania Desk-holder, Partners in International Medical Education
◾Past National Chairman of the Christian Medical and Dental Fellowship of Australia
◾Past Member of Advisory Council for South Australian Stillbirth and Neonatal Death Support Group
Qualifications
◾2001 FRCP (London)
◾1993 FRCOG
◾1988 MD (Cantab)
◾1987 Certificate of Accreditation (JCHMT), Endocrinology and Obstetric Medicine
◾1983 MRCOG
◾1978 MRCP(UK)
◾1975 MA (Cantab)
◾1975 MB, BChir (Cantab)
◾1972 BA (Cantab)
Research Interests
◾The benefits of the diagnosis and management of early gestational diabetes in women at risk : the TOBOGM RCT
◾Follow-up of offspring of women with eGDM in the TOBOGM RCT ; The TOMTHUMB study
◾The comparison of pregnancy and health economic outcomes in women diagnosed as gestational diabetes (GDM) using ADIPS-1998 criteria compared with those diagnosed using IADPSG criteria
◾The comparison of pregnancy and health economic outcomes in women diagnosed as GDM randomised to "tight" and "very tight" glucose control
◾The prevalence of MODY genotypes in South Australian women with GDM
◾Metformin as an alternative to insulin in the management of women with GDM : the MiG RCT
◾Follow-up of offspring of women with GDM treated with metformin or insulin ; The MiG-TOFU study
◾Metformin in the prevention of recurrent GDM
◾Metformin effects on insulin resistance in women with GDM
◾Metformin effects on vitamin B12 metabolism in women with GDM
◾Pharmacokinetics of metformin in women with GDM
◾Metformin for women who are obese during pregnancy for improving maternal and infant outcomes : the GROW RCT
◾Postpartum SMS reminders to women who have had GDM to test for type 2 diabetes: a randomised controlled trial: The DIAMIND study
◾The place of low molecular weight heparin in the prevention of recurrent utero-placental thrombosis and associated diseases in women with thrombophilia : the TIPPS and FRUIT RCTs
◾The role of genetic and acquired thrombophilia, including polymorphisms of methylenetetrahydrofolate reductase, activated protein C resistance, prothrombin gene mutation, protein S deficiency, hyperhomocysteinaemia and antiphospholipid antibodies in the aetiology of pre-eclampsia, placental abruption, intra-uterine growth restriction and recurrent miscarriage
◾The role of genetic thrombophilia, including polymorphisms of methylenetetrahydrofolate reductase, activated protein C resistance and the prothrombin gene mutation in the aetiology of cerebral palsy
◾The relationship of pre-eclampsia to the subsequent development of vascular disease and its link to hyperhomocysteinaemia
◾The effect of folate supplementation on the prevention of pre-eclampsia: the Folic Acid Clinical Trial (FACT) RCT
◾Follow-up of offspring of women treated with high dose folic acid compared with normal controls : the FACT for CHILD study
◾Investigations in the Folic Acid Clinical Trial - the INFACT study
◾The effect of folate supplementation on the prevention of recurrent pre-eclampsia in women with hyperhomocysteinaemia : the HOPE study
◾Longitudinal study of genome stability in the mother, fetus, neonate and child in relation to folate and B12 status
◾The role of common polymorphisms in the methylenetetrahydrofolate reductase, methionine synthase and thymidylate synthase genes as determinants of genome stability in mothers, fetuses, neonates and children
◾The diagnosis and treatment of severe early onset intrahepatic cholestasis of pregnancy (ICP) : the TURRIFIC RCT
◾The prevalence of ICP in South Australia
◾Treatment of obstetric cholestasis: the PITCH RCT
◾Genetic mechanisms of bile transporters
◾The aetiology of microvesicular hepatic steatosis and its relationship to clinical outcomes in women and sheep
◾The total Bile Acid Comparison and Harmonisation (BACH) project: a sub-study of the TURRIFIC RCT
◾The potential value of extra-cellular vesicles to assess cholestasis in pregnancy
◾The exploration of the gut microbiome in the aetiology of ICP
◾The long-term outcome of the offspring of women who have had ICP using linkage studies
◾The control of hypertension in pregnancy: the CHIPS RCT
◾Follow-up of the offspring of the CHIPS study: the CHIPS-CHILD study
◾The Australasian Maternity Outcomes Surveillance System (AMOSS)
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Appointments
Date Position Institution name 2012 - ongoing Professor University of Adelaide -
Research Interests
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Journals
Year Citation 2024 Seifu, C. N., Immanuel, J., Hague, W. M., Teede, H., Cheung, N. W., Hibbert, E. J., . . . TOBOGM Research Group. (2024). Association Between Immediate Treatment of Early Gestational Diabetes Mellitus and Breastfeeding Outcomes: Findings From the TOBOGM Study. Diabetes Care, 47(12), e99-e101.
Scopus42024 Simmons, D., Immanuel, J., Hague, W. M., Teede, H., Nolan, C. J., Peek, M. J., . . . TOBOGM Research Group. (2024). Perinatal Outcomes in Early and Late Gestational Diabetes Mellitus After Treatment From 24-28 Weeks' Gestation: A TOBOGM Secondary Analysis. Diabetes Care, 47(12), 2093-2101.
Scopus8 Europe PMC12024 Simmons, D., Immanuel, J., Hague, W. M., Teede, H., Nolan, C. J., Peek, M. J., . . . TOBOGM Research Group. (2024). Regression From Early GDM to Normal Glucose Tolerance and Adverse Pregnancy Outcomes in the Treatment of Booking Gestational Diabetes Mellitus Study. Diabetes Care, 47(12), 2079-2084.
Scopus5 Europe PMC12024 Haque, M. M., Tannous, W. K., Herman, W. H., Immanuel, J., Hague, W. M., Teede, H., . . . Simmons, D. (2024). Cost-effectiveness of diagnosis and treatment of early gestational diabetes mellitus: economic evaluation of the TOBOGM study, an international multicenter randomized controlled trial. eClinicalMedicine, 71, 102610-1-102610-11.
Scopus4 Europe PMC12024 Giles, S. K., Hague, W. M., & Edwards, R. A. (2024). ICP - could there be a virus in the works?. Obstetric Medicine, 17(3), 175-178.
2024 Sweeting, A., Enticott, J., Immanuel, J., Hague, W. M., Teede, H., Nolan, C. J., . . . TOBOGM Research Group. (2024). Relationship Between Early-Pregnancy Glycemia and Adverse Outcomes: Findings From the TOBOGM Study. Diabetes Care, 47(12), 2085-2092.
Scopus12024 Simmons, D., Immanuel, J., Hague, W. M., Coat, S., Teede, H., Nolan, C. J., . . . Cheung, N. W. (2024). Effect of treatment for early gestational diabetes mellitus on neonatal respiratory distress: A secondary analysis of the TOBOGM study. BJOG: an International Journal of Obstetrics and Gynaecology, 1-9.
Scopus2 Europe PMC22024 Markus, C., & Hague, W. B. (2024). Measuring bile acids: Are we all talking the same language?. Obstetric Medicine, 17(3), 162-167.
2024 Hague, W. B., Williamson, C., & Beuers, U. (2024). Intrahepatic cholestasis of pregnancy: Introduction and overview 2024. Obstetric Medicine, 17(3), 138-143.
Scopus1 Europe PMC22024 Jesudason, S., Safi, N., Li, Z., Brown, M., Hague, W., Makris, A., . . . Sullivan, E. (2024). Significant kidney disease in pregnancy: Feasibility and outcomes of a national population-based study using the Australasian Maternity Outcomes Surveillance System. Australian and New Zealand Journal of Obstetrics and Gynaecology, 8 pages.
2024 Hague, W. M. B. (2024). Hanns-Ulrich Marschall (15.2.1954-1.8.2023). Obstetric Medicine, 17(3), 137.
2024 Cheung, N. W., Rhou, Y. J. J., Immanuel, J., Hague, W. M., Teede, H., Nolan, C. J., . . . Simmons, D. (2024). Postpartum dysglycaemia after early gestational diabetes: Follow-up of women in the TOBOGM randomised controlled trial. Diabetes Research and Clinical Practice, 218, 6 pages.
Scopus12024 Immanuel, J., Cheung, N. W., Mohajeri, M., Simmons, D. J., Hague, W. M., Teede, H., . . . TOBOGM Research Group. (2024). Association Between Glycemia, Glycemic Variability, and Pregnancy Complications in Early GDM. Diabetes Care, 48(2), 285-291.
2024 Yuen, L., Wong, V., Immanuel, J., Hague, W. M., Cheung, N. W., Teede, H., . . . TOBOGM consortium. (2024). Ethnic Differences in Characteristics of Women Diagnosed with Early Gestational Diabetes: Findings from the TOBOGM Study. Journal of Clinical Endocrinology and Metabolism, dgae838-1-dgae838-14.
2023 Markus, C., Coat, S., Marschall, H. -U., Matthews, S., Loh, T. P., Rankin, W., & Hague, W. M. (2023). Lot-to-lot reagent changes and commutability of quality testing materials for total bile acid measurements. Clinical Chemistry and Laboratory Medicine, 61(7), e108-e111.
Scopus2 WoS1 Europe PMC12023 Khong, T. Y., Gordijn, S. J., Schoots, M. H., Ganzevoort, W., Groom, K. M., Coat, S., & Hague, W. M. (2023). Real-world experience of adding placental histopathology studies into perinatal clinical trials. Placenta, 136, 26-28.
Scopus2 Europe PMC12023 Leggett, C., Ritchie, U., Costi, L., Borg, C., Elliot, D., Mangoni, A. A., & Hague, W. M. (2023). Response to Dr. Anderson's Letter to the Editor: Modafinil and Armodafinil in Human Milk. J Hum Lact, 39(2), 224-225.
2023 Simmons, D., Immanuel, J., Hague, W. M., Teede, H., Nolan, C. J., Peek, M. J., . . . TOBOGM Research Group. (2023). Treatment of Gestational Diabetes Mellitus Diagnosed Early in Pregnancy. New England Journal of Medicine, 388(23), 2132-2144.
Scopus134 WoS7 Europe PMC552023 Reyes, P. A., Immanuel, J., Hague, W. M., Teede, H., Hibbert, E., Nolan, C. J., . . . Simmons, D. (2023). The relationship between body mass index and sleep in women with risk factors for gestational diabetes mellitus. Obesity Science and Practice, 9(6), 573-580.
Scopus1 Europe PMC12023 Hague, W. M., Briley, A., Callaway, L., Dekker Nitert, M., Gehlert, J., Graham, D., . . . Waugh, J. (2023). Intrahepatic cholestasis of pregnancy - Diagnosis and management: A consensus statement of the Society of Obstetric Medicine of Australia and New Zealand (SOMANZ): Executive summary. Australian and New Zealand Journal of Obstetrics and Gynaecology, 63(5), 656-665.
Scopus10 WoS2 Europe PMC62023 Simmons, D., Immanuel, J., Hague, W. M., Teede, H., Nolan, C. J., Peek, M. J., . . . Cheung, N. W. (2023). Treatment of Gestational Diabetes Mellitus Diagnosed Early in Pregnancy. Obstetrical and Gynecological Survey, 78(11), 636-637.
2022 Ovadia, C., Mitchell, A. L., Markus, C., Hague, W. M., & Williamson, C. (2022). Bile acid reference intervals for evidence-based practice.. BJOG : an international journal of obstetrics and gynaecology, 129(11), 1897-1898.
2022 Markus, C., Tan, R. Z., Lim, C. Y., Rankin, W., Matthews, S. J., Loh, T. P., & Hague, W. M. (2022). Performance of four regression frameworks with varying precision profiles in simulated reference material commutability assessment. Clinical Chemistry and Laboratory Medicine, 60(8), 1164-1174.
Scopus1 WoS12022 Dixon, P. H., Levine, A. P., Cebola, I., Chan, M. M. Y., Amin, A. S., Aich, A., . . . Williamson, C. (2022). GWAS meta-analysis of intrahepatic cholestasis of pregnancy implicates multiple hepatic genes and regulatory elements.. Nature communications, 13(1), 18 pages.
Scopus24 WoS4 Europe PMC112022 Leggett, C., Ritchie, U., Costi, L., Elliot, D., Mangoni, A. A., & Hague, W. M. (2022). Infant Exposure to Armodafinil Through Human Milk Following Maternal Use of Modafinil. Journal of Human Lactation, 39(2), 218-222.
Scopus2 WoS22021 Hague, W. M., Callaway, L., Chambers, J., Chappell, L., Coat, S., de Haan-Jebbink, J., . . . Williamson, C. (2021). A multi-centre, open label, randomised, parallel-group, superiority Trial to compare the efficacy of URsodeoxycholic acid with RIFampicin in the management of women with severe early onset Intrahepatic Cholestasis of pregnancy: the TURRIFIC randomised trial. BMC Pregnancy and Childbirth, 21(1), 51-1-51-14.
Scopus30 WoS17 Europe PMC122021 Van Dam, J. M., Goldsworthy, M. R., Hague, W. M., Coat, S., & Pitcher, J. B. (2021). Cortical Plasticity and Interneuron Recruitment in Adolescents Born to Women with Gestational Diabetes Mellitus. Brain Sciences, 11(3), 1-12.
Scopus3 WoS3 Europe PMC22021 Versace, V. L., Beks, H., Wesley, H., McNamara, K., Hague, W., Anjana, R. M., . . . Dunbar, J. A. (2021). Metformin for preventing type 2 diabetes mellitus in women with a previous diagnosis of gestational diabetes: a narrative review. Seminars in Reproductive Medicine, 38(6), 366-376.
Scopus3 WoS2 Europe PMC22021 Ovadia, C., Sajous, J., Seed, P. T., Patel, K., Williamson, N. J., Attilakos, G., . . . Williamson, C. (2021). Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis. The Lancet Gastroenterology and Hepatology, 6(7), 547-558.
Scopus85 WoS17 Europe PMC402021 Markus, C., Coat, S., Marschall, H. -U., Williamson, C., Dixon, P., Fuller, M., . . . Hague, W. M. (2021). The BACH project protocol: an international multicentre total Bile Acid Comparison and Harmonisation project and sub-study of the TURRIFIC randomised trial.. Clinical chemistry and laboratory medicine, 59(12), 1921-1929.
Scopus11 WoS2 Europe PMC42021 Ovadia, C., Sajous, J., Seed, P. T., Patel, K., Williamson, N. J., Attilakos, G., . . . Williamson, C. (2021). Ursodeoxycholic Acid in Intrahepatic Cholestasis of Pregnancy: A Systematic Review and Individual Participant Data Meta-analysis. OBSTETRICAL & GYNECOLOGICAL SURVEY, 76(9), 521-523.
2020 Leggett, C., Lwin, E. M. P., Ritchie, U., Song, Y., Gerber, J. P., Turner, S., . . . Garg, S. (2020). Perindopril in Breast Milk and Determination of Breastfed Infant Exposure: A Prospective Observational Study. DRUG DESIGN DEVELOPMENT AND THERAPY, 14, 961-967.
Scopus5 WoS2 Europe PMC22020 Thaventhiran, J. E. D., Lango Allen, H., Burren, O. S., Rae, W., Greene, D., Staples, E., . . . Bleda, M. (2020). Whole-genome sequencing of a sporadic primary immunodeficiency cohort. Nature, 583(7814), 90-95.
Scopus158 Europe PMC1062020 Thaventhiran, J. E. D., Lango Allen, H., Burren, O. S., Rae, W., Greene, D., Staples, E., . . . Bleda, M. (2020). Whole-genome sequencing of a sporadic primary immunodeficiency cohort. Nature, 583(7814), 90-95.
Scopus158 Europe PMC1062020 Mousa, A., Løvvik, T., Hilkka, I., Carlsen, S. M., Morin-Papunen, L., Tertti, K., . . . Teede, H. J. (2020). Metformin in Pregnancy Study (MiPS): protocol for a systematic review with individual patient data meta-analysis. BMJ Open, 10(5), e036981-1-e036981-8.
Scopus9 WoS7 Europe PMC32020 Turro, E., Astle, W. J., Megy, K., Gräf, S., Greene, D., Shamardina, O., . . . Hague, W. (2020). Whole-genome sequencing of patients with rare diseases in a national health system. Nature, 583(7814), 96-102.
Scopus355 Europe PMC2612020 Thaventhiran, J., Lango Allen, H., Burren, O., Rae, W., Greene, D., Staples, E., . . . Bleda, M. (2020). Publisher Correction: Whole-genome sequencing of a sporadic primary immunodeficiency cohort (Nature, (2020), 583, 7814, (90-95), 10.1038/s41586-020-2265-1). Nature, 584(7819), E2.
Scopus4 Europe PMC42020 Walker, K. F., Chappell, L. C., Hague, W. M., Middleton, P., & Thornton, J. G. (2020). Pharmacological interventions for treating intrahepatic cholestasis of pregnancy. Cochrane Database of Systematic Reviews, 2020(7), 82 pages.
Scopus74 WoS39 Europe PMC392020 Simmons, D., Rudland, V. L., Wong, V., Flack, J., Mackie, A., Ross, G. P., . . . Cheung, N. W. (2020). Options for screening for gestational diabetes mellitus during the SARS-CoV-2 pandemic. Australian and New Zealand Journal of Obstetrics and Gynaecology, 60(5), 660-666.
Scopus11 Europe PMC72019 Yeap, S. P., Harley, H., Thompson, R., Williamson, K. D., Bate, J., Sethna, F., . . . Hague, W. (2019). Biliary transporter gene mutations in severe intrahepatic cholestasis of pregnancy: Diagnostic and management implications. Journal of Gastroenterology and Hepatology (Australia), 34(2), 425-435.
Scopus9 WoS7 Europe PMC32019 Dodd, J., Louise, J., Deussen, A., Grivell, R., Dekker, G., McPhee, A., & Hague, W. (2019). Effect of metformin in addition to dietary and lifestyle advice for pregnant women who are overweight or obese: the GRoW randomised, double-blind, placebo-controlled trial. The Lancet Diabetes & Endocrinology, 7(1), 15-24.
Scopus75 WoS60 Europe PMC362019 Ovadia, C., Seed, P. T., Sklavounos, A., Geenes, V., Di Illio, C., Chambers, J., . . . Williamson, C. (2019). Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses. The Lancet, 393(10174), 899-909.
Scopus359 WoS243 Europe PMC1582019 Wen, S. W., White, R. R., Rybak, N., Gaudet, L. M., Robson, S., Hague, W., . . . Walker, M. C. (2019). Effect of high dose folic acid supplementation in pregnancy on pre-eclampsia (fact): Double blind, Phase III, randomised controlled, international, multicentre trial. Obstetrical and Gynecological Survey, 74(2), 68-70.
Scopus12019 Safi, N., Sullivan, E., Li, Z., Brown, M., Hague, W., McDonald, S., . . . Jesudason, S. (2019). Serious kidney disease in pregnancy: An Australian national cohort study protocol. BMC Nephrology, 20(1), 7 pages.
Scopus10 WoS6 Europe PMC32019 Wei, W., Tuna, S., Keogh, M. J., Smith, K. R., Aitman, T. J., Beales, P. L., . . . Hague, W. (2019). Germline selection shapes human mitochondrial DNA diversity. SCIENCE, 364(6442), 12 pages.
WoS111 Europe PMC1232019 Ovadia, C., Seed, P. T., Sklavounos, A., Geenes, V., Di Illio, C., Chambers, J., . . . Williamson, C. (2019). Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: Results of aggregate and individual patient data meta-analyses. Obstetrical and Gynecological Survey, 74(7), 388-390.
2018 Lwin, E. M. P., Leggett, C., Ritchie, U., Gerber, C., Song, Y., Hague, W., . . . Garg, S. (2018). Transfer of rosuvastatin into breast milk: Liquid chromatography-mass spectrometry methodology and clinical recommendations. Drug Design, Development and Therapy, 12, 3645-3651.
Scopus16 WoS7 Europe PMC52018 Rowan, J. A., Rush, E. C., Plank, L. D., Lu, J., Obolonkin, V., Coat, S., & Hague, W. M. (2018). Metformin in gestational diabetes: the offspring follow-up (MiG TOFU): body composition and metabolic outcomes at 7-9 years of age. Obstetrical and Gynecological Survey, 73(10), 565-567.
Scopus4 WoS42018 Rowan, J., Rush, E., Plank, L., Lu, J., Obolonkin, V., Coat, S., & Hague, W. (2018). Metformin in gestational diabetes: the offspring follow-up (MiG TOFU): body composition and metabolic outcomes at 7-9 years of age. BMJ Open Diabetes Research & Care, 6(1), e000456-1-e000456-12.
Scopus230 WoS159 Europe PMC1012018 Van Dam, J., Garrett, A., Schneider, L., Hodyl, N., Goldsworthy, M., Coat, S., . . . Pitcher, J. (2018). Reduced Cortical Excitability, Neuroplasticity, and Salivary Cortisol in 11–13-Year-Old Children Born to Women with Gestational Diabetes Mellitus. EBioMedicine, 31, 143-149.
Scopus30 WoS16 Europe PMC182018 Simmons, D., Hague, W. M., Teede, H. J., Cheung, N. W., Hibbert, E. J., Nolan, C. J., . . . Rajagopal, R. (2018). Hyperglycaemia in early pregnancy: the treatment of booking gestational diabetes mellitus (TOBOGM) study. A randomised controlled trial. The Medical journal of Australia, 209(9), 405.e1-405.e6.
Scopus49 WoS37 Europe PMC202018 Lwin, E., Gerber, C., Leggett, C., Song, Y., Ritchie, U., Turner, S., . . . Garg, S. (2018). Estimation of Atenolol Transfer Into Milk and Infant Exposure During Its Use in Lactating Women. Journal of Human Lactation, 34(3), 592-599.
Scopus7 WoS6 Europe PMC52018 Dodd, J. M., Grivell, R. M., Deussen, A. R., & Hague, W. M. (2018). Metformin for women who are overweight or obese during pregnancy for improving maternal and infant outcomes. Cochrane Database of Systematic Reviews, 2018(7), CD010564-1-CD010564-35.
Scopus53 WoS37 Europe PMC262018 Wen, S., White, R., Rybak, N., Gaudet, L., Robson, S., Hague, W., . . . Walker, M. (2018). Effect of high dose folic acid supplementation in pregnancy on pre-eclampsia (FACT): Double blind, phase III, randomised controlled, international, multicentre trial. BMJ (Online), 362, 8 pages.
Scopus87 WoS59 Europe PMC392017 Wouldes, T. A., Battin, M., Coat, S., Rush, E. C., Hague, W. M., & Rowan, J. A. (2017). Neurodevelopmental Outcome at 2 Years in Offspring of Women Randomised to Metformin or Insulin Treatment for Gestational Diabetes. Obstetrical and Gynecological Survey, 72(3), 149-151.
Scopus2 WoS12017 Marathe, J. A., Lim, W. H., Metz, M. P., Scheil, W., Dekker, G. A., & Hague, W. M. (2017). A retrospective cohort review of intrahepatic cholestasis of pregnancy in a South Australian population. European Journal of Obstetrics Gynecology and Reproductive Biology, 218, 33-38.
Scopus43 WoS29 Europe PMC212017 Tieu, J., Coat, S., Hague, W., Middleton, P., & Shepherd, E. (2017). Oral anti-diabetic agents for women with established diabetes/impaired glucose tolerance or previous gestational diabetes planning pregnancy, or pregnant women with pre-existing diabetes. Cochrane Database of Systematic Reviews, 2017(10), 1-82.
Scopus20 WoS9 Europe PMC62017 Farrant, M., Williamson, K., Battin, M., Hague, W., & Rowan, J. (2017). The use of dextrose/insulin infusions during labour and delivery in women with gestational diabetes mellitus: Is there any point?. Australian and New Zealand Journal of Obstetrics and Gynaecology, 57(3), 378-380.
Scopus3 WoS3 Europe PMC22017 Dass Singh, M., Fenech, M., Hague, W., Owens, J., Thomas, P., Hor, M., & Theodora, A. (2017). Infant birth outcomes are associated with DNA damage biomarkers as measured by the cytokinesis block micronucleus cytome assay: the DADHI study. Mutagenesis, 32(3), 355-370.
Scopus11 WoS10 Europe PMC42016 Vidler, M., Magee, L. A., von Dadelszen, P., Rey, E., Ross, S., Asztalos, E., . . . Trenowden, S. A. (2016). Women's views and postpartum follow-up in the CHIPS Trial (Control of Hypertension in Pregnancy Study). European Journal of Obstetrics Gynecology and Reproductive Biology, 206, 105-113.
Scopus9 Europe PMC22016 Ahmed, R. J., Gafni, A., Hutton, E. K., Hu, Z. J., Pullenayegum, E., Von Dadelszen, P., . . . Magee, L. A. (2016). The Cost Implications of Less Tight Versus Tight Control of Hypertension in Pregnancy (CHIPS Trial). Hypertension, 68(4), 1049-1055.
Scopus11 Europe PMC62016 Magee, L. A., Von Dadelszen, P., Singer, J., Lee, T., Rey, E., Ross, S., . . . Moutquin, J. M. (2016). The CHIPS randomized controlled trial (control of hypertension in pregnancy study). Hypertension, 68(5), 1153-1159.
Scopus180 Europe PMC722016 Dodd, J. M., Grivell, R. M., Deussen, A. R., Dekker, G., Louise, J., & Hague, W. (2016). Metformin and dietary advice to improve insulin sensitivity and promote gestational restriction of weight among pregnant women who are overweight or obese: The GRoW randomised trial. BMC Pregnancy and Childbirth, 16(1), 359-1-359-7.
Scopus7 WoS7 Europe PMC42016 Van Ryswyk, E., Middleton, P., Hague, W., & Crowther, C. (2016). Women's views on postpartum testing for type 2 diabetes after gestational diabetes: Six month follow-up to the DIAMIND randomised controlled trial. Primary Care Diabetes, 10(2), 91-102.
Scopus38 WoS25 Europe PMC202016 Van Hoorn, M., Hague, W., Van Pampus, M., Bezemer, D., & De Vries, J. (2016). Low-molecular-weight heparin and aspirin in the prevention of recurrent early-onset pre-eclampsia in women with antiphospholipid antibodies: The FRUIT-RCT. European Journal of Obstetrics and Gynecology and Reproductive Biology, 197, 168-173.
Scopus69 WoS54 Europe PMC282016 Voormolen, D., Abell, S., James, R., Hague, W., & Mol, B. (2016). Diagnostic criteria and treatment for gestational diabetes mellitus. Seminars in Reproductive Medicine, 34(2), 102-109.
Scopus14 WoS11 Europe PMC72016 Wouldes, T., Battin, M., Coat, S., Rush, E., Hague, W., & Rowan, J. (2016). Neurodevelopmental outcome at 2 years in offspring of women randomised to metformin or insulin treatment for gestational diabetes. Archives of Disease in Childhood: Fetal and Neonatal Edition, 101(6), F488-F493.
Scopus71 WoS50 Europe PMC342016 Abheiden, C. N. H., Van Hoorn, M. E., Hague, W. M., Kostense, P. J., Van Pampus, M. G., & De Vries, J. I. P. (2016). Authors' reply re: Does low-molecular-weight heparin influence fetal growth or uterine and umbilical arterial Doppler in women with a history of earlyonset uteroplacental insufficiency and an inheritable thrombophilia? Secondary randomised controlled trial results.. BJOG: An International Journal of Obstetrics and Gynaecology, 123(5), 843.
2016 Abheiden, C., van Hoorn, M., Hague, W., Kostense, P., van Pampus, M., & de Vries, J. (2016). Authors' reply re: Does low-molecular-weight heparin influence fetal growth or uterine and umbilical arterial Doppler in women with a history of early-onset uteroplacental insufficiency and an inheritable thrombophilia? Secondary randomised controlled trial results. BJOG : an international journal of obstetrics and gynaecology, 123(5), 844-845.
2016 Abheiden, C. N. H., Van Hoorn, M. E., Hague, W. M., Kostense, P. J., van Pampus, M. G., & de Vries, J. I. P. (2016). Does low-molecular-weight heparin influence fetal growth and uterine and umbilical arterial flow-velocities in women with a history of early-onset utero-placental insufficiency and an inheritable thrombophilia? Secondary RCT results. BJOG: an International Journal of Obstetrics and Gynaecology, 123(5), 797-805.
Scopus22 WoS16 Europe PMC82015 Rodger, M. A., Hague, W. M., Kingdom, J., Kahn, S. R., Karovitch, A., Sermer, M., . . . Wells, P. S. (2015). Antepartum dalteparin versus no antepartum dalteparin for the prevention of pregnancy complications in pregnant women with thrombophilia (TIPPS): A multinational open-label randomised trial. Obstetrical and Gynecological Survey, 70(2), 76-78.
2015 Van Ryswyk, E., Middleton, P., Hague, W., & Crowther, C. (2015). Postpartum SMS reminders to women who have experienced gestational diabetes to test for Type 2 diabetes: the DIAMIND randomized trial. Diabetic Medicine, 32(10), 1368-1376.
Scopus37 WoS34 Europe PMC232015 Geenes, V., Chambers, J., Khurana, R., Shemer, E., Sia, W., Mandair, D., . . . Williamson, C. (2015). Rifampicin in the treatment of severe intrahepatic cholestasis of pregnancy. European Journal of Obstetrics and Gynecology and Reproductive Biology, 189, 59-63.
Scopus80 WoS65 Europe PMC372015 Geenes, V., Chambers, J., Khurana, R., Wikstrom-Shemer, E., Sia, W., Mandair, D., . . . Williamson, C. (2015). Rifampicin in the treatment of intrahepatic cholestasis of pregnancy. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 122, 1. 2015 Rodger, M. A., Hague, W. M., Kingdom, J., Kahn, S. R., & Wells, P. S. (2015). Dalteparin for pregnant women with thrombophilia - Authors' reply. The Lancet, 385(9969), 690.
Scopus1 WoS1 Europe PMC12015 Battin, M., Obolonkin, V., Rush, E., Hague, W., Coat, S., & Rowan, J. (2015). Blood pressure measurement at two years in offspring of women randomized to a trial of metformin for GDM: follow up data from the MiG trial. BMC Pediatrics, 15(1), 54-1-54-5.
Scopus31 WoS28 Europe PMC172015 Van Ryswyk, E., Middleton, P., Shute, E., Hague, W., & Crowther, C. (2015). Women's views and knowledge regarding healthcare seeking for gestational diabetes in the postpartum period: A systematic review of qualitative/survey studies. Diabetes Research and Clinical Practice, 110(2), 109-122.
Scopus59 WoS45 Europe PMC432015 Singh, M., Thomas, P., Owens, J., Hague, W., & Fenech, M. (2015). Potential role of folate in pre-eclampsia. Nutrition Reviews, 73(10), 694-722.
Scopus23 WoS14 Europe PMC102014 Van Ryswyk, E., Middleton, P., Hague, W., & Crowther, C. (2014). Clinician views and knowledge regarding healthcare provision in the postpartum period for women with recent gestational diabetes: a systematic review of qualitative/survey studies. Diabetes Research and Clinical Practice, 106(3), 401-411.
Scopus39 WoS29 Europe PMC242014 Barrett, H., Nitert, M., McIntyre, H., Hague, W., Callaway, L., & Rowan, J. (2014). Predictors of preeclampsia in women in the Metformin in Gestational Diabetes(Mig) study. Journal of Diabetes & Metabolism, 5(7), 395-1-395-8.
WoS22014 Rodger, M., Hague, W., Kingdom, J., Kahn, S., Karovitch, A., Sermer, M., . . . Wells, P. (2014). Antepartum dalteparin versus no antepartum dalteparin for the prevention of pregnancy complications in pregnant women with thrombophilia (TIPPS): a multinational open-label randomised trial. The Lancet, 384(9955), 1673-1683.
Scopus202 WoS164 Europe PMC1032014 Dorniak-Wall, T., Grivell, R., Dekker, G., Hague, W., & Dodd, J. (2014). The role of L-arginine in the prevention and treatment of pre-eclampsia: a systematic review of randomised trials. Journal of Human Hypertension, 28(4), 230-235.
Scopus62 WoS54 Europe PMC302013 Eames, A., Grivell, R., Deussen, A., Hague, W., & Dodd, J. (2013). Metformin for women who are obese during pregnancy for improving maternal and infant outcomes. The Cochrane Database of Systematic Reviews, 2013(6), 1-9.
Scopus102013 Gurung, V., Middleton, P., Milan, S., Hague, W., & Thornton, J. (2013). Interventions for treating cholestasis in pregnancy. The Cochrane Database of Systematic Reviews, 2013(6), 1-144.
Scopus56 WoS68 Europe PMC292013 Barrett, H., Nitert, M., Jones, L., O'Rourke, P., Lust, K., Gatford, K., . . . Rowan, J. (2013). Determinants of maternal triglycerides in women with gestational diabetes mellitus in the Metformin in Gestational Diabetes (MiG) study. Diabetes Care, 36(7), 1941-1946.
Scopus27 WoS23 Europe PMC142013 Gatford, K., Houda, C., Lu, Z., Coat, S., Baghurst, P., Owens, J., . . . Hague, W. (2013). Vitamin B12 and homocysteine status during pregnancy in the metformin in gestational diabetes trial: responses to maternal metformin compared with insulin treatment. Diabetes Obesity & Metabolism, 15(7), 660-667.
Scopus20 WoS15 Europe PMC142013 Heatley, E., Middleton, P., Hague, W., & Crowther, C. (2013). The DIAMIND study: postpartum SMS reminders to women who have had gestational diabetes mellitus to test for type 2 diabetes: a randomised controlled trial - study protocol. BMC Pregnancy and Childbirth, 13(1), 1-6.
Scopus42 WoS37 Europe PMC272013 Barrett, H., Gatford, K., Houda, C., De Blasio, M., McIntyre, H., Callaway, L., . . . Rowan, J. (2013). Maternal and neonatal circulating markers of metabolic and cardiovascular risk in the Metformin in Gestational Diabetes (MiG) trial: Responses to maternal metformin versus insulin treatment. Diabetes Care, 36(3), 529-536.
Scopus38 WoS33 Europe PMC282013 Furness, D., Fenech, M., Dekker, G., Khong, T., Roberts, C., & Hague, W. (2013). Folate, Vitamin B12, Vitamin B6 and homocysteine: impact on pregnancy outcome. Maternal and Child Nutrition, 9(2), 155-166.
Scopus84 WoS75 Europe PMC522012 de Vries, J., van Pampus, M., Hague, W., Bezemer, P., & Joosten, J. (2012). Low-molecular-weight heparin added to aspirin in the prevention of recurrent early-onset pre-eclampsia in women with inheritable thrombophilia: the FRUIT-RCT. Journal of Thrombosis and Haemostasis, 10(1), 64-72.
Scopus150 WoS141 Europe PMC912012 Crowther, C., Hague, W., Middleton, P., Baghurst, P., McPhee, A., Tran, T., . . . Robinson, J. (2012). The IDEAL study: investigation of dietary advice and lifestyle for women with borderline gestational diabetes: a randomised controlled trial - study protocol. BMC Pregnancy and Childbirth, 12(106), 2-8.
Scopus15 WoS13 Europe PMC72012 Rowan, J. A., Rush, E. C., Obolonkin, V., Battin, M., Wouldes, T., & Hague, W. M. (2012). Response to comments on: Rowan et al. Metformin in gestational diabetes: The offspring follow-up (MiG TOFU): Body composition at 2 years of age. Diabetes Care 2011;34:2279-2284. Diabetes Care, 35(3), E30.
2012 De Vries, J. I. P., Hague, W. M., & Van Pampus, M. G. (2012). Low-molecular-weight heparin added to aspirin in the prevention of recurrent early-onset pre-eclampsia in women with inheritable thrombophilia: the FRUIT-RCT: a reply to a rebuttal. Journal of Thrombosis and Haemostasis, 10(6), 1196.
Scopus11 WoS22012 Gayford, K., McCarthy, A., & Hague, W. M. (2012). A case of postpartum Group B streptococcal meningitis. OBSTETRIC MEDICINE, 5(1), 25-26.
WoS22011 Wickramasinghe, N., Troshani, I., Hill, S., Hague, W., & Goldberg, S. (2011). A transaction cost assessment of a pervasive technology solution for gestational diabetes. International Journal of Healthcare Information Systems and Informatics, 6(4), 60-76.
Scopus12 WoS42011 de Vries, J. I., van Pampus, M. G., Hague, W. M., Bezemer, P. D., & Joosten, J. H. (2011). Fractionated Heparin in Pregnant Women with a History of Uteroplacental Insufficiency and Thrombophilia, a Randomized Trial (The FRUIT Study). REPRODUCTIVE SCIENCES, 18(3), 352A. 2011 Miragoli, M., Kadir, S., Sheppard, M., Salvarani, N., Virta, M., Wells, S., . . . Gorelik, J. (2011). A protective antiarrhythmic role of ursodeoxycholic acid in an in vitro rat model of the cholestatic fetal heart. Hepatology, 54(4), 1282-1292.
Scopus76 WoS63 Europe PMC452011 Rowan, J., Rush, E., Obolonkin, V., Battin, M., Wouldes, T., & Hague, W. (2011). Metformin in gestational diabetes: The Offspring Follow-Up (MiG TOFU): body composition at 2 years of age. Diabetes Care, 34(10), 2279-2284.
Scopus303 WoS232 Europe PMC1642010 Rowan, J., Gao, W., Hague, W., & McIntyre, H. (2010). Glycemia and its relationship to outcomes in the metformin in Gestational Diabetes Trial. Diabetes Care, 33(1), 9-16.
Scopus72 WoS60 Europe PMC492010 Furness, D., Dekker, G., Hague, W., Khong, T., & Fenech, M. (2010). Increased lymphocyte micronucleus frequency in early pregnancy is associated prospectively with pre-eclampsia and/or intrauterine growth restriction. Mutagenesis, 25(5), 489-498.
Scopus49 WoS38 Europe PMC262010 Chittleborough, C., Baldock, K., Taylor, A., Hague, W., Willson, T., Martin, W., . . . Phillips, P. (2010). Long-term follow-up of women with gestational diabetes mellitus: The South Australian Gestational Diabetes Mellitus Recall Register. Australian & New Zealand Journal of Obstetrics & Gynaecology, 50(2), 127-131.
Scopus26 WoS25 Europe PMC132010 Seppelt, I., Sullivan, E., Bellomo, R., Ellwood, D., Finfer, S., Howe, B., . . . Robinson, J. (2010). Critical illness due to 2009 A/H1N1 influenza in pregnant and postpartum women: population based cohort study. BMJ-BRITISH MEDICAL JOURNAL, 340(mar18 3), 6 pages.
WoS123 Europe PMC1212009 de Vries, J. I., Kist, W. J., & Hague, W. M. (2009). Confounded thrombophilia studies in preeclampsia. American Journal of Obstetrics and Gynecology, 201(5), e11-e12.
2009 Hague, W. (2009). Diabetes insipidus in pregnancy. Obstetric Medicine, 2(4), 138-141.
WoS7 Europe PMC22009 Hotham, N., Ilett, K., Hackett, L., Morton, M., Muller, P., & Hague, W. (2009). Transfer of metyrapone and Its metabolite, rac-Metyrapol, into Breast milk. Journal of Human Lactation, 25(4), 451-454.
Scopus8 WoS6 Europe PMC32009 Tieu, J., Coat, S., Hague, W., & Middleton, P. (2009). Oral anti-diabetic agents for women with pre-existing diabetes mellitus/impaired glucose tolerance or previous gestational diabetes mellitus. The Cochrane Database of Systematic Reviews, (2), 007724-1-007724-10.
Scopus18 WoS11 Europe PMC82009 Hull, M., Nemeth, D., Hague, W., Wilkinson, C., Liebelt, J., Lane, M., & Inglis, D. (2009). Mitochondrial fatty acid transport enzyme deficiency-implications for in vitro fertilization. Fertility and Sterility, 91(6), 11-14.
Scopus2 WoS22009 Djukic, M., Gibson, C., MacLennan, A., Goldwater, P., Haan, E., McMichael, G., . . . Casey, G. (2009). Genetic susceptibility to viral exposure may increase the risk of cerebral palsy. Australian & New Zealand Journal of Obstetrics & Gynaecology, 49(3), 247-253.
Scopus29 WoS27 Europe PMC202008 Rodger, M., Paidas, M., McLintock, C., Middeldorp, S., Kahn, S., Martinelli, I., . . . Greer, I. (2008). Inherited thrombophilia and pregnancy complications revisited. Obstetrics and Gynecology, 112(2 Part 1), 320-324.
Scopus112 WoS101 Europe PMC772008 van Gellekom, S., Lindauer-van der Werf, G., Hague, W., & de Vries, J. (2008). Anaemia and haemolysis in pregnancy due to rapid folic acid and vitamin B12 depletion. Netherlands Journal of Medicine, 66(5), 216-217.
Scopus3 WoS2 Europe PMC12008 Rowan, J., Hague, W., Gao, W., Battin, M., & Moore, M. (2008). Metformin versus insulin for the treatment of gestational diabetes. New England Journal of Medicine, 358(19), 2003-2016.
Scopus946 WoS536 Europe PMC4472008 Kist, W., Janssen, N., Kalk, J., Hague, W., Dekker, G., & de Vries, J. (2008). Thrombophilias and adverse pregnancy outcome - A confounded problem!. Thrombosis and Haemostasis, 99(1), 77-85.
Scopus81 WoS70 Europe PMC462008 Rowan, J. A., Hague, W. M., Gao, W., Battin, M. R., & Moore, M. P. (2008). Metformin versus insulin for the treatment of gestational diabetes. Obstetrical and Gynecological Survey, 63(10), 616-618.
Scopus32008 Rodger, M. A., Paidas, M., McLintock, C., Middeldorp, C., Kahn, S., Martinelli, I., . . . Greer, I. (2008). Erratum: Inherited thrombophilia and pregnancy complications revisited (Obstetrics & Gynecology (2008) 112 (320-324)). Obstetrics and Gynecology, 112(6), 1392.
2007 Moss, J., Crowther, C., Hiller, J., Willson, K., & Robinson, J. (2007). Costs and consequences of treatment for mild gestational diabetes mellitus - evaluation from the ACHOIS randomised trial. BMC Pregnancy and Childbirth, 7(27), 1-7.
Scopus94 Europe PMC502007 Rodger, M., Kahn, S., Cranney, A., Hodsman, A., Kovacs, M., Clement, A., . . . Hague, W. (2007). Long-term dalteparin in pregnancy not associated with a decrease in bone mineral density: Substudy of a randomized controlled trial. Journal of Thrombosis and Haemostasis, 5(8), 1600-1606.
Scopus83 WoS59 Europe PMC452007 Williams, V., Griffiths, A., Carbone, S., & Hague, W. (2007). Fibrinogen concentration and factor VIII activity in women with preeclampsia. Hypertension in Pregnancy, 26(4), 415-421.
Scopus21 WoS17 Europe PMC172007 Hague, W. (2007). Metformin in pregnancy and lactation. Australian Prescriber, 30(3), 68-69.
Scopus3 WoS22006 Rakhorst, A. C., Dekker, G. A., Erwich, J. J. H. M., & Hague, W. M. (2006). Patterns of risk factors for recurrent preeclampsia in women with a history of early-onset preeclampsia.. HYPERTENSION IN PREGNANCY, 25, 186. 2006 Williams, V. K., Griffiths, A. B. M., Carbone, S., & Hague, W. M. (2006). Fibrinogen concentration and Factor VIII activity in women with preeclampsia.. HYPERTENSION IN PREGNANCY, 25, 184. 2006 Gibson, C., MacLennan, A., Janssen, N., Kist, W., Hague, W., Haan, E., . . . Dekker, G. (2006). Associations between fetal inherited thrombophilia and adverse pregnancy outcomes. American Journal of Obstetrics and Gynecology, 194(4), 947e1-947e10.
Scopus37 WoS25 Europe PMC132006 Gibson, C., MacLennan, A., Goldwater, P., Haan, E., Priest, K., Dekker, G., . . . Morton, M. (2006). The association between inherited cytokine polymorphisms and cerebral palsy. American Journal of Obstetrics and Gynecology, 194(3), 674e1-674e11.
Scopus61 WoS38 Europe PMC332006 Charles, B., Norris, R., XIAO, X., & Hague, W. (2006). Population pharmacokinetics of metformin in late pregnancy. Therapeutic Drug Monitoring, 28(1), 67-72.
Scopus174 WoS137 Europe PMC982005 Gibson, C., MacLennan, A., Hague, W., Haan, E., Priest, K., Chan, A., & Dekker, G. (2005). Associations between inherited thrombophilias, gestational age, and cerebral palsy. American Journal of Obstetrics and Gynecology, 193(4), 1437.e1-1437.e12.
Scopus60 WoS42 Europe PMC342005 Ward, E., McIntyre, A., Van Kessel, G., & Hague, W. (2005). Immediate blood pressure changes and aquatic physiotherapy. Hypertension in Pregnancy, 24(2), 93-102.
Scopus4 WoS3 Europe PMC22005 Gibson, C., MacLennan, A., Rudzki, Z., Hague, W., Haan, E., Sharpe, P., . . . Khong, T. (2005). The prevalence of inherited thrombophilias in a Caucasian Australian population. Pathology, 37(2), 160-163.
Scopus26 WoS22 Europe PMC162004 Norman, R., Wang, J., & Hague, W. (2004). Should we continue or stop insulin sensitizing drugs during pregnancy?. Current Opinion in Obstetrics & Gynecology, 16(3), 245-250.
Scopus50 WoS40 Europe PMC352003 Hague, W., Davoren, P., Oliver, J., & Rowan, J. (2003). Contraindications to use of metformin - Metformin may be useful in gestational diabetes. British Medical Journal, 326(7392), 762-763.
Scopus33 WoS48 Europe PMC172003 Hague, W., & Dekker, G. (2003). Risk factors for thrombosis in pregnancy. Best Practice & Research Clinical Haematology, 16(2), 197-210.
Scopus27 WoS13 Europe PMC132003 Hague, W. (2003). Homocysteine and pregnancy. Best Practice & Research in Clinical Obstetrics & Gynaecology, 17(3), 459-469.
Scopus127 WoS114 Europe PMC732003 Elder, A. T., Hague, W. M., Davoren, P. M., Oliver, J., Rowan, J., Jones, P., . . . Jones, G. C. (2003). Contraindications to use of metformin. BMJ, 326(7392), 762.
Scopus42 Europe PMC92002 Brink, A., Akande, W., Moodley, J., Hague, W., Hall, D., Steyn, W., . . . Odendaal, H. (2002). Hypertension in pregnancy: Round-table discussion: Part I. Cardiovascular Journal of South Africa, 13(1), 22-28. 2002 Brink, A., Akande, W., Moodley, J., Hague, W., Hall, D., Steyn, W., . . . Odendaal, H. (2002). Hypertension in pregnancy. Round-table discussion: Part 2. Cardiovascular Journal of South Africa, 13(2), 68-72.
Scopus2 Europe PMC12002 Hague, W. (2002). Cardiac intraventricular thrombus in protein C deficiency. Journal of the Royal Society of Medicine, 95(8), 426.
2002 Brink, A., Akande, W., Moodley, J., Hague, W., Hall, D., Steyn, W., . . . Odendaal, H. (2002). Hypertension in pregnancy : round-table discussion: part 1: cardiovascular profile. Cardiovascular Journal of South Africa, 13(1), 22-28. 2001 Khong, T., Moore, L., & Hague, W. (2001). Thrombophilias and adverse pregnancy outcome. Human Reproduction, 16(2), 395-396.
WoS2 Europe PMC42001 Hague, W., North, R., Gallus, A., Walters, B., Orlikowski, C., Burrows, R., . . . Peek, M. (2001). Anticoagulation in pregnancy and the puerperium. Medical Journal of Australia, 175(5), 258-263.
Scopus37 WoS26 Europe PMC162001 Khong, T., & Hague, W. (2001). Biparental contribution to fetal thrombophilia in discordant twin intrauterine growth restriction. American Journal of Obstetrics and Gynecology, 185(1), 244-245.
Scopus33 WoS26 Europe PMC252001 Hague, W. M. (2001). Endocrine disease (including diabetes). Best Practice and Research: Clinical Obstetrics and Gynaecology, 15(6), 877-889.
Scopus4 WoS3 Europe PMC12001 Khong, T. Y., Moore, L., & Hague, W. M. (2001). Thrombophilias and adverse pregnancy outcome (multiple letters). Human Reproduction, 16(2), 395-397.
Scopus5 Europe PMC12000 Brown, M. A., Hague, W. M., Higgins, J., Lowe, S., McCowan, L., Oats, J., . . . Walters, B. N. J. (2000). The detection, investigation and management of hypertension in pregnancy: Full consensus statement. Australian and New Zealand Journal of Obstetrics and Gynaecology, 40(2), 139-155.
Scopus240 Europe PMC1622000 Brown, M. A., Hague, W. M., Higgins, J., Lowe, S., McCowan, L., Oats, J., . . . Walters, B. N. J. (2000). The detection, investigation and management of hypertension in pregnancy: Executive summary. Australian and New Zealand Journal of Obstetrics and Gynaecology, 40(2), 133-138.
Scopus189 Europe PMC1102000 Crocker, H., Pfitzner, J., Doyle, I., Hague, W., Smith, B., & Ruffin, R. (2000). Pulmonary alveolar proteinosis: two contrasting cases. European Respiratory Journal, 15(2), 426-429.
Scopus11 WoS9 Europe PMC51999 Hague, W. M. (1999). Pre-existing endocrine disease in relation to pregnancy. Current Obstetrics and Gynaecology, 9(2), 62-68.
Scopus51999 Crowther, C., Hiller, J., Pridmore, B., Bryce, R., Duggan, P., Hague, W., & Robinson, J. (1999). Calcium supplementation in nulliparous women for the prevention of pregnancy-induced hypertension, preeclampsia and preterm birth: an Australian randomised trial. Australian and New Zealand Journal of Obstetrics and Gynaecology, 39(1), Dec-18.
Scopus91 WoS80 Europe PMC551999 Khong, T., & Hague, W. (1999). The placenta in maternal hyperhomocysteinaeima. British Journal of Obstetrics and Gynaecology, 106(3), 273-278.
Scopus60 WoS48 Europe PMC231998 Norman, R., Huber Buchholz, M. M., & Hague, W. (1998). Genetic and environmental origins of polycyctic ovary syndrome. Contemporary Reviews in Obstetrics and Gynecology, 10(6), 141-149. 1998 Terry, A., & Hague, W. (1998). Postpartum thyroiditis. Seminars in Perinatology, 22(6), 497-502.
Scopus21 WoS8 Europe PMC51998 Hague, W. (1998). A practical approach to amenorrhoea. New Ethicals Journal, 1(12), 61-70. 1998 Norman, R., Huber-Buchholz, M., & Hague, W. (1998). Genetic and environmental origins of polycystic ovary syndrome. Contemporary Reviews in Obstetrics and Gynaecology, 10(2), 141-149.
Scopus21997 Hague, W. (1997). A practical approach to Amenorrhoea. Current Therapeutics, 38(5), 57-65. 1996 Norman, R., Masters, S., & Hague, W. (1996). Hyperinsulinemia is common in family members of women with polycystic ovary syndrome. Fertility and Sterility, 66(6), 942-947.
Scopus118 WoS92 Europe PMC581995 Norman, R., Masters, S., Hague, W., Beng, C., Pannall, P., & Wang, J. (1995). Metabolic approaches to the subclassification of Polycystic Ovary Syndrome. Fertility and Sterility, 63(2), 329-335.
Scopus81 WoS74 Europe PMC311995 Brennecke, S., Brown, M., Crowther, C., Hague, W., & King, J. (1995). Aspirin and prevention of preeclampsia. Australian and New Zealand Journal of Obstetrics and Gynaecology, 35(1), 38-41.
1995 Norman, R., Hague, W., Masters, S., & Wang, X. (1995). Subjects with polycystic ovaries without hyperandrogenaemia exhibit similar disturbances in insulin and lipid profiles as those with Polycystic Ovary Syndrome. Human Reproduction, 10(9), 2258-2261.
Scopus77 WoS68 Europe PMC421994 Kennedy, S., Hall, P. D. L. M., Seymour, A. E., & Hague, W. M. (1994). Transient diabetes insipidus and acute fatty liver of pregnancy. BJOG: An International Journal of Obstetrics & Gynaecology, 101(5), 387-391.
Scopus88 Europe PMC251993 Slattery, M. A., Khang, T. Y., Dawkins, R. R., Pridmore, B. R., & Hague, W. M. (1993). Eclampsia in association with partial molar pregnancy and congenital abnormalities. American Journal of Obstetrics and Gynecology, 169(6), 1625-1627.
Scopus16 Europe PMC41992 Hague, W. M. (1992). Premature menopause management.. Australian family physician, 21(3), 252-254. 1990 HAGUE, W. M., ADAMS, J., RODDA, C., BROOK, C. G. D., DE BRUYN, R., GRANT, D. B., & JACOBS, H. S. (1990). THE PREVALENCE OF POLYCYSTIC OVARIES IN PATIENTS WITH CONGENITAL ADRENAL HYPERPLASIA AND THEIR CLOSE RELATIVES. Clinical Endocrinology, 33(4), 501-510.
Scopus146 Europe PMC901990 HAGUE, W. M., ADAMS, J., ALGAR, V., DRUMMOND, V., SCHWARZ, G., BOTTAZZO, G., & JACOBS, H. S. (1990). HLA ASSOCIATIONS IN PATIENTS WITH POLYCYSTIC OVARIES AND IN PATIENTS WITH CONGENITAL ADRENAL HYPERPLASIA CAUSED BY 21‐HYDROXYLASE DEFICIENCY. Clinical Endocrinology, 32(4), 407-416.
Scopus21 Europe PMC81990 Hague, W. M., & Norman, R. J. (1990). Recent advances in understanding of normal hormone mechanisms of the female reproductive system. Current Opinion in Obstetrics and Gynecology, 2(3), 363-369. 1989 HAGUE, W. M., HONOUR, J. W., ADAMS, J., VECSEI, P., & JACOBS, H. S. (1989). STEROID RESPONSES TO ACTH IN WOMEN WITH POLYCYSTIC OVARIES. Clinical Endocrinology, 30(4), 355-365.
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Scopus7 Europe PMC21988 HAGUE, W. M., ADAMS, J., REEDERS, S. T., PETO, T. E. A., & JACOBS, H. S. (1988). FAMILIAL POLYCYSTIC OVARIES: A GENETIC DISEASE?. Clinical Endocrinology, 29(6), 593-605.
Scopus162 Europe PMC841988 LAW, A., HAGUE, W. M., DALY, J. G., HONOUR, J. W., TAYLOR, N., JEFFCOATE, S. L., . . . JOPLIN, G. F. (1988). INAPPROPRIATE ACTH CONCENTRATIONS IN TWO PATIENTS WITH FUNCTIONING ADRENOCORTICAL CARCINOMA. Clinical Endocrinology, 29(1), 53-62.
Scopus3 Europe PMC11988 Rumsby, G., Fielder, A. H. L., Hague, W. M., & Honour, J. W. (1988). Heterogeneity in the gene locus for steroid 21-hydroxylase deficiency. Journal of Medical Genetics, 25(9), 596-599.
Scopus11 Europe PMC51987 Hague, W. M. (1987). Treatment of endocrine diseases. British Medical Journal (Clinical research ed.), 294(6567), 297-300.
Scopus1 Europe PMC11987 Hague, W. M., Tan, S. L., Adams, J., & Jacobs, H. S. (1987). Hypergonadotropic amenorrhea - etiology and outcome in 93 young women. International Journal of Gynecology and Obstetrics, 25(2), 121-125.
Scopus16 Europe PMC51986 Tan, S. L., Hague, W. M., Becker, F., & Jacobs, H. S. (1986). Autoimmune premature ovarian failure with polyendocrinopathy and spontaneous recovery of ovarian follicular activity. Fertility and Sterility, 45(3), 421-424.
Scopus20 Europe PMC101986 Hague, W. M., & de Swiet, M. (1986). A syndrome ot liver damage and intravascular coagulation in the last trimester of normotensive pregnancy. A clinical and histopathological study. BJOG: An International Journal of Obstetrics & Gynaecology, 93(10), 1113-1114.
1986 Chapman, M. G., Katz, M., Dowsett, M., Hague, W., Jeffcoate, S. L., & Dewhurst, C. J. (1986). Spironolactone in the Treatment of Hirsutism. Acta Obstetricia et Gynecologica Scandinavica, 65(4), 349-350.
Scopus8 Europe PMC41986 HAGUE, W. M., ABDULWAHID, N. A., JACOBS, H. S., & CRAFT, I. (1986). Use of LHRH analogue to obtain reversible castration in a patient with benign metastasizing leiomyoma. BJOG: An International Journal of Obstetrics & Gynaecology, 93(4), 455-460.
Scopus51 Europe PMC271985 HAGUE, W. M., & MILLAR, D. R. (1985). Excessive testosterone secretion in pregnancy. Case report. BJOG: An International Journal of Obstetrics & Gynaecology, 92(2), 173-178.
Scopus7 Europe PMC41984 Hague, W., Wallace, R., Sims, C., & Gau, G. (1984). Placenta accreta in a uterus didelphys (bicollis). Journal of Obstetrics and Gynaecology, 5(2), 104-105. 1984 SLATER, D. N., & HAGUE, W. M. (1984). Renal morphological changes in idiopathic acute fatty liver of pregnancy. Histopathology, 8(4), 567-581.
Scopus30 Europe PMC131983 HAGUE, W. M., & HONOUR, J. W. (1983). MALIGNANT HYPERTENSION IN CONGENITAL ADRENAL HYPERPLASIA DUE TO 11β‐HYDROXYLASE DEFICIENCY. Clinical Endocrinology, 18(5), 505-510.
Scopus30 Europe PMC141983 Hague, W. M., Duncan, S. L. B., Fenton, D. W., & Slater, D. N. (1983). Acute fatty liver of pregnancy. Journal of the Royal Society of Medicine, 76(8), 652-661.
Scopus24 Europe PMC121982 HAGUE, W. M., MUNRO, D. S., SAWERS, R. S., DUNCAN, S. L. B., & HONOUR, J. W. (1982). Long‐term effects of cyproterone acetate on the pituitary adrenal axis in adult women. BJOG: An International Journal of Obstetrics & Gynaecology, 89(12), 981-984.
Scopus8 Europe PMC91980 Hague, W. M. (1980). MEDIASTINAL AND SUBCUTANEOUS EMPHYSEMA IN A PREGNANT PATIENT WITH ASTHMA CASE REPORT. BJOG: An International Journal of Obstetrics & Gynaecology, 87(5), 440-443.
Scopus7 Europe PMC3 -
Book Chapters
Year Citation 2019 Hague, W. M., & Roberts-Thomson, I. C. (2019). Liver and Gastrointestinal Disorders During Pregnancy. In M. Wichmann, T. K. McCullough, I. C. Roberts-Thomson, & G. J. Maddern (Eds.), Gastroenterology For General Surgeons (pp. 237-243). Springer International Publishing.
DOI2015 Henry, C., & Hague, W. M. (2015). Type 2 diabetes mellitus. In Case Studies in Assisted Reproduction: Common and Uncommon Presentations (pp. 1-6). Cambridge University Press.
DOI2015 Morton, M. R., & Hague, W. M. (2015). A woman with hypertension. In Case Studies in Assisted Reproduction: Common and Uncommon Presentations (pp. 7-11). Cambridge University Press.
DOI Scopus12015 Clark, E., & Hague, W. M. (2015). A patient with severe lupus. In Case Studies in Assisted Reproduction: Common and Uncommon Presentations (pp. 33-37). Cambridge University Press.
DOI2015 Jesudason, S., & Hague, W. M. (2015). A woman with renal impairment. In Case Studies in Assisted Reproduction: Common and Uncommon Presentations (pp. 19-23). Cambridge University Press.
DOI2013 Wickramasinghe, N., Troshani, I., Hill, S. R., Hague, W., & Goldberg, S. (2013). A transaction cost assessment of a pervasive technology solution for gestational diabetes. In Healthcare Information Technology Innovation and Sustainability: Frontiers and Adoption (pp. 109-126). IGI Global.
DOI Scopus52007 Hague, W. (2007). Effects of pregnancy on the endocrine system. In I. Greer, C. Nelson-Piercy, & B. Walters (Eds.), Maternal Medicine: Medical Problems in Pregnancy (pp. 70-73). UK: Churchill Livingstone. 2007 Hague, W. (2007). Parathyroid, Adrenal and Pituitary Disease in Pregnancy. In I. Greer, C. Nelson-Piercy, & B. Walters (Eds.), Maternal Medicine: Medical Problems in Pregnancy (pp. 78-82). UK. 1995 Hague, W. (1995). Treatment of endocrine diseases. In Prescribing in Pregnancy (pp. 85-96). British Medical Journal Publishing Group. -
Conference Papers
Year Citation 2024 Capatina, N., Williamson, C., Hague, W., Chambers, J., & Ovadia, C. (2024). A core outcome set for studies of intrahepatic cholestasis of pregnancy. In BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY Vol. 132 (pp. 61-62). WILEY. 2010 Goldberg, S., Troshani, I., Rao Hill, S., Hague, W., & Wickramasinghe, N. (2010). A pervasive technology solution for diabetes using gestational diabetes as a model. In Proceedings of AMCIS 2010 Vol. 3 (pp. 1-21). online: AMCIS.
Scopus12004 Furness, D., Fenech, M., Khong, T., Hague, W., & Dekker, G. (2004). Evaluation of the use of the CBMN assay to determine inter-individual variation in spontaneous and folate deficiency-induced genome damage in humans. In (Asia Pacific Journal of Clinical Nutrition vol 13 suppl) includes Proceedings of the IUNS/APCNS conference "International Congress of Clinical Nutrition" (pp. S56). HEC Press. -
Conference Items
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Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2012 - 2015 Co-Supervisor Improving Postpartum Healthcare and Health Outcomes of Women with a History Gestational Diabetes Mellitus Doctor of Philosophy Doctorate Full Time Dr Emer Van Ryswyk 2011 - 2017 Principal Supervisor Diet and DNA damage in infants The DADHI study Doctor of Philosophy Doctorate Full Time Mrs Mansi Dass Singh 2005 - 2008 Co-Supervisor Genome Damage and Folate Nutrigenomics in Uteroplacental Insufficiency Doctor of Philosophy Doctorate Full Time Dr Denise Furness
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