Dr Beverly Muhlhausler
I am a NHMRC Career Development Award Fellow (Level 2) and lead the Obesity and Metabolic Health Division of the FOODplus Research Centre at the University of Adelaide.My work on the impact of maternal overnutrition on the programming of obesity and metabolic disease has made a significant contribution to current understanding of how exposure to maternal obesity and/or an excess nutrient supply before birth acts to alter the development of key systems involved in the regulation of energy balance. A key focus of my current research is identifying and testing nutritional interventions which can be applied during the perinatal period to improve metabolic health through the life-course, and I am currently leading basic science projects and clinical trials in this area. Since 2008, my work has included a specific focus on the role of maternal omega-3 fatty acid supplementation in determining growth and metabolic health of the infant and child, and I have published 15 original research papers and 4 reviews in the fatty acid field since 2012.
Appointments
| Date | Position | Institution name |
|---|---|---|
| 2017 - 2010 | NHMRC Peter Doherty Postdoctoral Fellow, Sansom Institute for Health Research, | University of South Australia |
| 2017 | President | Australia and New Zealand Society for the Developmental Origins of Health and Disease |
| 2015 | National Health and Medical Research Council (NHMRC) Career Development Award Fellow (Level 2) | The University of Adelaide |
| 2014 | Treasurer | International Society for the Study of Fatty Acids and Lipids |
| 2014 - 2017 | Secretary | Australia and New Zealand Society for the Developmental Origins of Health and Disease |
| 2014 | Deputy Director, FOODplus Research Centre | The University of Adelaide |
| 2011 - 2015 | National Health and Medical Research Council (NHMRC) Career Development Award Fellow | The University of Adelaide |
| 2010 | Head, Obesity and Metabolic Health Division, FOODplus Research Centre | The University of Adelaide, |
| 2006 - 2007 | Postdoctoral Fellow | University of South Australia |
Language Competencies
| Language | Competency |
|---|---|
| German | Can read, write, speak, understand spoken and peer review |
Education
| Date | Institution name | Country | Title |
|---|---|---|---|
| 2012 - 2006 | The University of Adelaide | Australia | PhD |
| 1997 - 2001 | The University of Adelaide | Australia | BSc (First Class Honours) |
Keywords
Endocrinology & Metabolism, Medical and Health Sciences, Medical Biochemistry: Lipids, Neurosciences, Nutrition and Dietetics, Nutritional Physiology, Obstetrics and Gynaecology, Paediatrics, Physiology
Journals
| Date | Citation |
|---|---|
| 2017 | Toop,C, Muhlhausler,B, O'Dea,K, Gentili,S, 2017, Impact of perinatal exposure to sucrose or high fructose corn syrup (HFCS-55) on adiposity and hepatic lipid composition in rat offspring, Journal of Physiology, 595, 13, 4379-4398 10.1113/JP274066 |
| 2017 | Huynh,D, Condo,D, Gibson,R, Makrides,M, Muhlhausler,B, Zhou,S, 2017, Comparison of breast-milk iodine concentration of lactating women in Australia pre and post mandatory iodine fortification, Public Health Nutrition, 2, 1, 12-17 10.1017/S1368980016002032 |
| 2017 | Muhlhausler,B, 2017, Variability in the cardiometabolic effects of ω-3 long-chain PUFAs: background diet, timing, and genetics, American Journal of Clinical Nutrition, 105, 5, 1029-1030 10.3945/ajcn.117.155739 |
| 2017 | Kanakri,K, Carragher,J, Hughes,R, Muhlhausler,B, Gibson,R, 2017, A reduced cost strategy for enriching chicken meat with omega-3 long chain polyunsaturated fatty acids using dietary flaxseed oil, British Poultry Science, 1-7 10.1080/00071668.2017.1293798 |
| 2017 | Kanakri,K, Carragher,J, Muhlhausler,B, Hughes,R, Gibson,R, 2017, In ovo exposure to omega-3 fatty acids does not enhance omega-3 long-chain polyunsaturated fatty acid metabolism in broiler chickens, Journal of Developmental Origins of Health and Disease, 1-9 10.1017/S2040174417000216 |
| 2017 | Bazargan,M, Foster,D, Davey,A, Muhlhausler,B, 2017, Rosiglitazone Metabolism in Human Liver Microsomes Using a Substrate Depletion Method, Drugs in R and D, 17, 1, 189-198 10.1007/s40268-016-0166-4 |
| 2017 | Symon,B, Crichton,GE, Muhlhausler,B, 2017, Does the early introduction of solids promote obesity?, Singapore medical journal, - 10.11622/smedj.2017024 |
| 2017 | Peter,R, Gugusheff,J, Wooldridge,A, Gatford,K, Muhlhausler,B, 2017, Placental restriction in multi-fetal pregnancies and between-twin differences in size at birth alter neonatal feeding behaviour in the sheep, Journal of Developmental Origins of Health and Disease, 8, 3, 357-369 10.1017/S2040174417000137 |
| 2017 | Gatford,KL, Muhlhausler,BS, Huang,L, Sim,PS-L, Roberts,CT, Velhuis,JD, Chen,C, 2017, Rising maternal circulating GH during murine pregnancy suggests placental regulation, ENDOCRINE CONNECTIONS, 6, 4, 260-266 10.1530/EC-17-0032 |
| 2016 | Bazargan,M, Foster,D, Muhlhausler,B, Morrison,J, McMillen,C, Davey,A, 2016, Limited fetal metabolism of rosiglitazone: elimination via the maternal compartment in the pregnant ewe, Reproductive Toxicology, 61, 162-168 10.1016/j.reprotox.2016.04.008 |
| 2016 | Gugusheff,J, Bae,S, Rao,A, Clarke,I, Poston,L, Taylor,P, Coen,C, Muhlhausler,B, 2016, Sex and age-dependent effects of a maternal junk food diet on the mu-opioid receptor in rat offspring, Behavioural Brain Research, 301, 124-131 10.1016/j.bbr.2015.12.027 |
| 2016 | Do,T, Muhlhausler,B, Box,A, Able,A, 2016, Enrichment of antioxidant capacity and vitamin E in pita made from barley, Journal of Food Science, 81, 3, H777-H785 10.1111/1750-3841.13218 |
| 2016 | Pidsley,R, Zotenko,E, Peters,T, Lawrence,M, Risbridger,G, Molloy,P, Van Djik,S, Muhlhausler,B, Stirzaker,C, Clark,S et al, 2016, Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling, Genome Biology, 17, 1, 208-1-208-17 10.1186/s13059-016-1066-1 |
| 2016 | Condo,D, Huyhn,D, Anderson,A, Skeaff,S, Ryan,P, Makrides,M, Mühlhaüsler,B, Zhou,S, 2016, Iodine status of pregnant women in South Australia after mandatory iodine fortification of bread and the recommendation for iodine supplementation, Maternal and Child Nutrition, e12410-e12410 10.1111/mcn.12410 |
| 2016 | Hodyl,N, Muhlhausler,B, 2016, Novel insights, challenges and practical implications of DOHaD-omics research, Medical Journal of Australia, 204, 3, 108-110 10.5694/mja14.01626 |
| 2016 | Gugusheff,J, Sim,P, Kheng,A, Gentili,S, Al-Nussairawi,M, Brand-Miller,J, Muhlhausler,B, 2016, The effect of maternal and post-weaning low and high glycaemic index diets on glucose tolerance, fat deposition and hepatic function in rat offspring, Journal of Developmental Origins of Health and Disease, 7, 3, 320-329 10.1017/S2040174415007965 |
| 2016 | Carragher,JF, Muhlhausler,BS, Geier,MS, House,JD, Hughes,RJ, Gibson,RA, 2016, Effect of dietary ALA on growth rate, feed conversion ratio, mortality rate and breast meat omega-3 LCPUFA content in broiler chickens, Animal Production Science, 56, 5, 815-823 10.1071/AN14743 |
| 2016 | Leghi,G, Muhlhausler,B, 2016, The effect of n-3 LCPUFA supplementation on oxidative stress and inflammation in the placenta and maternal plasma during pregnancy, Prostaglandins Leukotrienes and Essential Fatty Acids, 113, 33-39 10.1016/j.plefa.2016.08.010 |
| 2016 | Clifton,V, Moss,T, Wooldridge,A, Gatford,K, Liravi,B, Kim,D, Muhlhausler,B, Morrison,J, Davies,A, De Matteo,R et al, 2016, Development of an experimental model of maternal allergic asthma during pregnancy, Journal of Physiology, 594, 5, 1311-1325 10.1113/jp270752 |
| 2016 | Prescott,S, Allen,K, Armstrong,K, Collins,C, Dickinson,H, Gardiner,K, Jacka,F, Jasoni,C, Moore,T, Moritz,K et al, 2016, The establishment of DOHaD working groups in Australia and New Zealand, Journal of Developmental Origins of Health and Disease, 7, 5, 433-439 10.1017/S2040174416000167 |
| 2016 | van Dijk,S, Zhou,J, Peters,T, Buckley,M, Sutcliffe,B, Oytam,Y, Gibson,R, McPhee,A, Yelland,L, Makrides,M et al, 2016, Effect of prenatal DHA supplementation on the infant epigenome: results from a randomized controlled trial, Clinical Epigenetics, 8, 1, 114-1-114-13 10.1186/s13148-016-0281-7 |
| 2016 | Kanakri,K, Muhlhausler,B, Carragher,J, Gibson,R, Barekatain,R, Dekoning,C, Drake,K, Hughes,R, 2016, Relationship between the fatty acid composition of uropygial gland secretion and blood of meat chickens receiving different dietary fats, Animal Production Science, Online, A-F 10.1071/AN16268 |
| 2016 | Dickinson,H, Moss,T, Gatford,K, Moritz,K, Akison,L, Fullston,T, Hryciw,D, Maloney,C, Morris,M, Wooldridge,A et al, 2016, A review of fundamental principles for animal models of DOHaD research: an Australian perspective, Journal of Developmental Origins of Health and Disease, 7, 5, 449-472 10.1017/S2040174416000477 |
| 2016 | Vithayathil,M, Gugusheff,J, Gibson,R, Ong,Z, Muhlhausler,B, 2016, Effect of a maternal cafeteria diet on the fatty acid composition of milk and offspring red blood cells, Prostaglandins Leukotrienes and Essential Fatty Acids, 109, 58-65 10.1016/j.plefa.2016.03.016 |
| 2016 | Bischof,R, Clifton,V, Wooldridge,A, Gatford,K, Liravi,B, Kim,D, Muhlhausler,B, Morrison,J, Davies,A, Dematteo,R et al, 2016, A SHEEP MODEL TO EXAMINE THE EFFECTS OF MATERNAL ASTHMA ON FETAL OUTCOMES, RESPIROLOGY, 21, 56-56 |
| 2015 | Huynh,D, Zhou,SJ, Gibson,R, Palmer,L, Muhlhausler,B, 2015, Validation of an optimized method for the determination of iodine in human breast milk by inductively coupled plasma mass spectrometry (ICPMS) after tetramethylammonium hydroxide extraction, Journal of Trace Elements in Medicine and Biology, 29, 75-82 10.1016/j.jtemb.2014.07.005 |
| 2015 | Van Dijk,S, Molloy,P, Varinli,H, Morrison,J, Muhlhausler,B, Buckley,M, Clark,S, McMillen,I, Noakes,M, Samaras,K et al, 2015, Epigenetics and human obesity, International Journal of Obesity, 39, 1, 85-97 10.1038/ijo.2014.34 |
| 2015 | Do,T, Cozzolino,D, Muhlhausler,B, Box,A, Able,A, 2015, Antioxidant capacity and vitamin E in barley: Effect of genotype and storage, Food Chemistry, 187, 65-74 10.1016/j.foodchem.2015.04.028 |
| 2015 | Liu,G, Mühlhäusler,B, Gibson,R, 2015, Evaluation of contamination associated with current blood spot technology for determining the fatty acid status of individuals, European Journal of Lipid Science and Technology, 117, 8, 1280-1286 10.1002/ejlt.201400470 |
| 2015 | Gugusheff,J, Ong,Z, Muhlhausler,B, 2015, The early origins of food preferences: targeting the critical windows of development, FASEB Journal, 29, 2, 365-373 10.1096/fj.14-255976 |
| 2015 | Wood,KE, Mantzioris,E, Gibson,RA, Ramsden,CE, Muhlhausler,BS, 2015, The effect of modifying dietary LA and ALA intakes on omega-3 long chain polyunsaturated fatty acid (n-3 LCPUFA) status in human adults: a systematic review and commentary, Prostaglandins Leukotrienes and Essential Fatty Acids, 95, April, 47-55 10.1016/j.plefa.2015.01.001 |
| 2015 | Do,T, Cozzolino,D, Muhlhausler,B, Box,A, Able,A, 2015, Effect of malting on antioxidant capacity and vitamin E content in different barley genotypes, Journal of the Institute of Brewing, 121, 4, 531-540 10.1002/jib.271 |
| 2015 | van Dijk,S, Tellam,R, Morrison,J, Muhlhausler,B, Molloy,P, 2015, Recent developments on the role of epigenetics in obesity and metabolic disease, Clinical Epigenetics, 7, 1, 66-1-66-13 10.1186/s13148-015-0101-5 |
| 2014 | Muhlhausler,B, 2014, Fatty acids in the infant diet: size matters, British Journal of Nutrition, 111, 2, 193-193 10.1017/S0007114513002365 |
| 2014 | Muhlhausler,B, Gibson,R, Yelland,L, Makrides,M, 2014, Heterogeneity in cord blood DHA concentration: towards an explanation, Prostaglandins, leukotrienes, and essential fatty acids, 91, 4, 135-140 10.1016/j.plefa.2014.07.013 |
| 2014 | Lie,S, Hui,M, McMillen,I, Muhlhausler,B, Posterino,G, Dunn,S, Wang,K, Botting,K, Morrison,J, 2014, Exposure to rosiglitazone, a PPAR-γ agonist, in late gestation reduces the abundance of factors regulating cardiac metabolism and cardiomyocyte size in the sheep fetus, American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 306, 6, R429-R437 10.1152/ajpregu.00431.2013 |
| 2014 | Gugusheff,J, Ong,Z, Muhlhausler,B, 2014, Naloxone treatment alters gene expression in the mesolimbic reward system in 'junk food' exposed offspring in a sex-specific manner but does not affect food preferences in adulthood, Physiology and Behavior, 133, 14-21 10.1016/j.physbeh.2014.04.007 |
| 2014 | Muhlhausler,BS, Vithayathil,MA, 2014, Impact of maternal obesity on offspring adipose tissue: lessons for the clinic, Expert Review of Endocrinology and Metabolism, 9, 6, 615-627 10.1586/17446651.2014.956088 |
| 2014 | Lee,A, Shandala,T, Nguyen,L, Muhlhausler,B, Chen,K, Howe,P, Xian,C, 2014, Effects of resveratrol supplementation on bone growth in young rats and microarchitecture and remodeling in ageing rats, Nutrients, 6, 12, 5871-5887 10.3390/nu6125871 |
| 2014 | Toop,C, Muhlhausler,B, O'Dea,K, Gentili,S, 2014, Consumption of sucrose, but not high fructose corn syrup, leads to increased adiposity and dyslipidaemia in the pregnant and lactating rat, Journal of Developmental Origins of Health and Disease, 6, 1, 38-46 10.1017/S2040174414000610 |
| 2014 | Ong,Z, Muhlhausler,B, 2014, Consuming a low-fat diet from weaning to adulthood reverses the programming of food preferences in male, but not in female, offspring of 'junk food'-fed rat dams, Acta Physiologica, 210, 1, 127-141 10.1111/apha.12132 |
| 2014 | Liu,G, Muehlhaeusler,B, Gibson,R, 2014, A method for long term stabilisation of long chain polyunsaturated fatty acids in dried blood spots and its clinical application, Prostaglandins, Leukotrienes and Essential Fatty Acids, 91, 6, 251-260 10.1016/j.plefa.2014.09.009 |
| 2014 | Wood,K, Lau,A, Mantzioris,E, Gibson,R, Ramsden,C, Muhlhausler,B, 2014, A low omega-6 polyunsaturated fatty acid (n-6 PUFA) diet increases omega-3 (n-3) long chain PUFA status in plasma phospholipids in humans, Prostaglandins, Leukotrienes and Essential Fatty Acids, 90, 4, 133-138 10.1016/j.plefa.2013.12.010 |
| 2014 | Rattanatray,L, Muhlhausler,B, Nicholas,L, Morrison,J, McMillen,I, 2014, Impact of maternal overnutrition on gluconeogenic factors and methylation of the phosphoenolpyruvate carboxykinase promoter in the fetal and postnatal liver, Pediatric Research, 75, 1, 14-21 10.1038/pr.2013.178 |
| 2013 | Ong,Z, Wanasuria,A, Lin,M, Hiscock,J, Muhlhausler,B, 2013, Chronic intake of a cafeteria diet and subsequent abstinence. Sex-specific effects on gene expression in the mesolimbic reward system, Appetite, 65, 189-199 10.1016/j.appet.2013.01.014 |
| 2013 | Neale,E, Muhlhausler,B, Probst,Y, Batterham,M, Fernandez,F, Tapsell,L, 2013, Short-term effects of fish and fish oil consumption on total and high molecular weight adiponectin levels in overweight and obese adults, Metabolism-clinical and Experimental, 62, 5, 651-660 10.1016/j.metabol.2012.10.014 |
| 2013 | Tu,W, Muhlhausler,B, James,M, Stone,D, Gibson,R, 2013, Dietary alpha-linolenic acid does not enhance accumulation of omega-3 long-chain polyunsaturated fatty acids in barramundi (Lates calcarifer), Comparative Biochemistry and Physiology B- Biochemistry and Molecular Biology, 164, 1, 29-37 10.1016/j.cbpb.2012.10.001 |
| 2013 | Muhlhausler,B, Gugusheff,J, Ong,Z, Vithayathil,M, 2013, Nutritional approaches to breaking the intergenerational cycle of obesity, Canadian Journal of Physiology and Pharmacology, 91, 6, 421-428 10.1139/cjpp-2012-0353 |
| 2013 | Nicholas,L, Rattanatray,L, MacLaughlin,S, Ozanne,S, Kleemann,D, Walker,S, Morrison,J, Zhang,S, Muhlhausler,B, Martin-Gronert,M et al, 2013, Differential effects of maternal obesity and weight loss in the periconceptional period on the epigenetic regulation of hepatic insulin-signaling pathways in the offspring, The FASEB Journal, 27, 9, 3786-3796 10.1096/fj.13-227918 |
| 2013 | Tu,W, Muhlhausler,B, Yelland,L, Gibson,R, 2013, Correlations between blood and tissue omega-3 LCPUFA status following dietary ALA intervention in rats, Prostaglandins Leukotrienes and Essential Fatty Acids, 88, 1, 53-60 10.1016/j.plefa.2012.04.005 |
| 2013 | Wood,K, Mantzioris,E, Gibson,R, Muhlhausler,B, 2013, Incorporating macadamia oil and butter to reduce dietary omega-6 polyunsaturated fatty acid intake, Nutrition & Dietetics, 70, 2, 94-100 10.1111/j.1747-0080.2012.01636.x |
| 2013 | Gugusheff,J, Vithayathil,M, Ong,Z, Muhlhausler,B, 2013, The effects of prenatal exposure to a 'junk food' diet on offspring food preferences and fat deposition can be mitigated by improved nutrition during lactation, Journal of Developmental Origins of Health and Disease, 4, 5, 348-357 10.1017/S2040174413000330 |
| 2013 | Muhlhausler,B, Gugusheff,J, Ong,Z, Vithayathil,M, 2013, Pregnancy, obesity and insulin resistance: maternal overnutrition and the target windows of fetal development, Hormone Molecular Biology and Clinical Investigation, 15, 1, 25-36 10.1515/hmbci-2013-0029 |
| 2013 | Gugusheff,J, Ong,Z, Muhlhausler,B, 2013, A maternal 'junk-food' diet reduces sensitivity to the opioid antagonist naloxone in offspring postweaning, The FASEB Journal, 27, 3, 1275-1284 10.1096/fj.12-217653 |
| 2013 | Molloy,P, Samaras,K, Muhlhausler,B, McMillen,C, 2013, Chasing the “ghost in our genes” to beat obesity, Medical Journal of Australia, 198, 4, 182-182 10.5694/mja13.10098 |
| 2013 | Lie,S, Duffield,J, McMillen,I, Morrison,J, Ozanne,S, Pilgrim,C, Muhlhausler,B, 2013, The effect of placental restriction on insulin signaling and lipogenic pathways in omental adipose tissue in the postnatal lamb, Journal of Developmental Origins of Health and Disease, 4, 5, 421-429 10.1017/S2040174413000202 |
| 2013 | Gray,B, Muhlhausler,B, Davies,P, Vitetta,L, 2013, Liver enzymes but not free fatty acid levels predict markers of insulin sensitivity in overweight and obese, nondiabetic adults, Nutrition Research, 33, 10, 781-788 10.1016/j.nutres.2013.07.019 |
| 2013 | Muhlhausler,B, Ailhaud,G, 2013, Omega-6 polyunsaturated fatty acids and the early origins of obesity, Current Opinion in Endocrinology, Diabetes and Obesity, 20, 1, 56-61 10.1097/MED.0b013e32835c1ba7 |
| 2013 | Muhlhausler,B, Bloomfield,F, Gillman,M, 2013, Whole animal experiments should be more like human randomized controlled trials, PLoS Biology, 11, 2, 1-6 10.1371/journal.pbio.1001481 |
| 2012 | Ong,Z, Gugusheff,J, Muhlhausler,B, 2012, Perinatal overnutrition and the programming of food preferences: pathways and mechanisms, Journal of Developmental Origins of Health and Disease, 3, 5, 299-308 10.1017/S204017441200030X |
| 2012 | Tu,W, Muhlhausler,B, James,M, Stone,D, Gibson,R, 2012, An alternative n-3 fatty acid elongation pathway utilising 18:3n-3 in barramundi (Lates calcarifer), Biochemical and Biophysical Research Communications, 423, 1, 176-182 10.1016/j.bbrc.2012.05.110 |
| 2012 | Mühlhäusler,B, 2012, Fat on the brain, Journal of Physiology, 590, 17, 4121-4121 10.1113/jphysiol.2012.239491 |
| 2012 | Tu,W, Cook-Johnson,R, James,M, Muhlhausler,B, Stone,D, Gibson,R, 2012, Barramundi (Lates calcarifer) desaturase with Δ6/Δ8 dual activities, Biotechnology Letters, 34, 7, 1283-1296 10.1007/s10529-012-0891-x |
| 2012 | Fong,L, Muhlhausler,B, Gibson,R, Xian,C, 2012, Perinatal maternal dietary supplementation of ω3-fatty acids transiently affects bone marrow microenvironment, osteoblast and osteoclast formation, and bone mass in male offspring, Endocrinology, 153, 5, 2455-2465 10.1210/en.2011-1917 |
| 2011 | Muhlhausler,B, Hancock,S, Bloomfield,F, Harding,R, 2011, Are twins growth restricted?, Pediatric Research, 70, 2, 117-122 10.1203/PDR.0b013e31821f6cfd |
| 2011 | Bazargan,M, Davey,A, Muhlhausler,B, Morrison,J, McMillen,I, Foster,D, 2011, Simple HPLC method for determination of rosiglitazone in sheep plasma and amniotic fluid and its application in a pregnant sheep model, Journal of Pharmaceutical and Biomedical Analysis, 55, 2, 360-365 10.1016/j.jpba.2011.01.026 |
| 2011 | Gibson,R, Muhlhausler,B, Makrides,M, 2011, Conversion of linoleic acid and alpha-linolenic acid to long chain polyunsaturated fatty acids (LCPUFAs), with a focus on pregnancy, lactation and the first 2 years of life, Maternal and Child Nutrition, 7, Suppl 2, 17-26 10.1111/j.1740-8709.2011.00299.x |
| 2011 | Muhlhausler,B, Ong,Z, 2011, The fetal origins of obesity: early origins of altered food intake, Endocrine, Metabolic & Immune Disorders - Drug Targets, 11, 3, 189-197 10.2174/187153011796429835 |
| 2011 | Muhlhausler,B, Gibson,R, Makrides,M, 2011, The effect of maternal omega-3 long-chain polyunsaturated fatty acid (n-3 LCPUFA) supplementation during pregnancy and/or lactation on body fat mass in the offspring: A systematic review of animal studies, Prostaglandins Leukotrienes and Essential Fatty Acids, 85, 2, 83-88 10.1016/j.plefa.2011.04.027 |
| 2011 | Ong,Z, Muhlhausler,B, 2011, Maternal "junk-food" feeding of rat dams alters food choices and development of the mesolimbic reward pathway in the offspring, The FASEB Journal, 25, 7, 2167-2179 10.1096/fj.10-178392 |
| 2011 | Muhlhausler,B, Miljkovic,D, Fong,L, Xian,C, Duthoit,E, Gibson,R, 2011, Maternal omega-3 supplementation increases fat mass in male and female rat offspring, Frontiers in Genetics, 2, 48, 1-10 10.3389/fgene.2011.00048 |
| 2010 | Morrison,J, Duffield,J, Muhlhausler,B, Gentili,S, McMillen,I, 2010, Fetal growth restriction, catch-up growth and the early origins of insulin resistance and visceral obesity, Pediatric Nephrology, 25, 4, 669-677 10.1007/s00467-009-1407-3 |
| 2010 | Nguyen,L, Muhlhausler,B, Botting,K, Morrison,J, 2010, Maternal undernutrition alters fat cell size distribution, but not lipogenic gene expression, in the visceral fat of the late gestation guinea pig fetus, Placenta, 31, 10, 902-909 10.1016/j.placenta.2010.07.014 |
| 2010 | Muhlhausler,B, Gibson,R, Makrides,M, 2010, Effect of long-chain polyunsaturated fatty acid supplementation during pregnancy or lactation on infant and child body composition: a systematic review, American Journal of Clinical Nutrition, 92, 4, 857-863 10.3945/ajcn.2010.29495 |
| 2010 | Muhlhausler,B, Cook-Johnson,R, James,M, Miljkovic,D, Duthoit,E, Gibson,R, 2010, Opposing effects of omega-3 and omega-6 long chain polyunsaturated fatty acids on the expression of lipogenic genes in omental and retroperitoneal adipose depots in the rat, Journal of Nutrition and Metabolism, 2010, 1-9 10.1155/2010/927836 |
| 2010 | Tu,W, Cook-Johnson,R, James,M, Muhlhausler,B, Gibson,R, 2010, Omega-3 long chain fatty acid synthesis is regulated more by substrate levels than gene expression, Prostaglandins Leukotrienes and Essential Fatty Acids, 83, 2, 61-68 10.1016/j.plefa.2010.04.001 |
| 2010 | Zhang,S, Rattanatray,L, MacLaughlin,S, Cropley,J, Suter,C, Molloy,L, Kleemann,D, Walker,S, Muhlhausler,B, Morrison,J et al, 2010, Periconceptional undernutrition in normal and overweight ewes leads to increased adrenal growth and epigenetic changes in adrenal IGF2/H19 gene in offspring, FASEB Journal, 24, 8, 2772-2782 10.1096/fj.09-154294 |
| 2010 | Rattanatray,L, MacLaughlin,S, Kleemann,D, Walker,S, Muhlhausler,B, McMillen,I, 2010, Impact of maternal periconceptional overnutrition on fat mass and expression of adipogenic and lipogenic genes in visceral and subcutaneous fat depots in the postnatal lamb, Endocrinology, 151, 11, 5195-5205 10.1210/en.2010-0501 |
| 2009 | Muhlhausler,B, Morrison,J, McMillen,I, 2009, Rosiglitazone increases the expression of peroxisome proliferator-activated receptor-γ target genes in adipose tissue, liver, and skeletal muscle in the sheep fetus in late gestation, Endocrinology, 150, 9, 4287-4294 10.1210/en.2009-0462 |
| 2009 | Duffield,J, Vuocolo,T, Tellam,R, McFarlane,J, Kauter,K, Muhlhausler,B, McMillen,I, 2009, Intrauterine growth restriction and the sex specific programming of leptin and peroxisome proliferator-activated receptor [gamma (PPAR gamma]) mRNA expression in visceral fat in the lamb, Pediatric Research, 66, 1, 59-65 10.1203/PDR.0b013e3181a7c121 |
| 2009 | Mühlhausler,B, 2009, Nutritional models of type 2 diabetes mellitus., Methods in molecular biology (Clifton, N.J.), 560, 19-36 |
| 2009 | Muhlhausler,B, Duffield,J, Ozanne,S, Pilgrim,C, Turner,N, Morrison,J, McMillen,I, 2009, The transition from fetal growth restriction to accelerated postnatal growth: a potential role for insulin signalling in skeletal muscle, Journal of Physiology-London, 587, 17, 4199-4211 10.1113/jphysiol.2009.173161 |
| 2009 | Muhlhausler,B, Smith,S, 2009, Early-life origins of metabolic dysfunction: role of the adipocyte, Trends in Endocrinology and Metabolism, 20, 2, 51-57 10.1016/j.tem.2008.10.006 |
| 2008 | McMillen,I, MacLaughlin,S, Muhlhausler,B, Gentili,S, Duffield,J, Morrison,J, 2008, Developmental origins of adult health and disease: The role of periconceptional and foetal nutrition, Basic ' Clinical Pharmacology ' Toxicology, 102, 2, 82-89 10.1111/j.1742-7843.2007.00188.x |
| 2008 | Duffield,J, Vuocolo,T, Tellam,R, Yuen,B, Muhlhausler,B, McMillen,I, 2008, Placental restriction of fetal growth decreases IGF1 and leptin mRNA expression in the perirenal adipose tissue of late gestation fetal sheep, American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 294, 5, R1413-R1419 10.1152/ajpregu.00787.2007 |
| 2008 | Muhlhausler,B, Adam,C, McMillen,I, 2008, Maternal nutrition and the programming of obesity: the brain, Organogenesis, 4, 3, 144-152 10.4161/org.4.3.6503 |
| 2008 | Philp,L, Muhlhausler,B, Janovska,A, Wittert,G, Duffield,J, McMillen,I, 2008, Maternal overnutrition suppresses the phosphorylation of 5 '-AMP-activated protein kinase in liver, but not skeletal muscle, in the fetal and neonatal sheep, American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 295, 6, R1982-R1990 10.1152/ajpregu.90492.2008 |
| 2008 | Muhlhausler,B, Ritorto,V, Schultz,C, Chatterton,B, Duffield,J, McMillen,I, 2008, Birth weight and gender determine expression of adipogenic, lipogenic and adipokine genes in perirenal adipose tissue in the young adult sheep, Domestic Animal Endocrinology, 35, 1, 46-57 10.1016/j.domaniend.2008.01.007 |
| 2007 | Muhlhausler,B, Adam,C, Findlay,P, Duffield,J, McMillen,I, 2007, Erratum: Increased maternal nutrition alters development of the appetite-regulating network in the brain (FASEB Journal DOI: 10.1096/fj.05-5241fje), FASEB Journal, 21, 2, 629- 10.1096/fj.05-5241err |
| 2007 | Muhlhausler,B, Duffield,J, McMillen,I, 2007, Increased maternal nutrition increases leptin expression in perirenal and subcutaneous adipose tissue in the postnatal lamb, Endocrinology, 148, 12, 6157-6163 10.1210/en.2007-0770 |
| 2007 | Muhlhausler,B, 2007, Programming of the appetite-regulating neural network: a link between maternal overnutrition and the programming of obesity?, Journal of Neuroendocrinology, 19, 1, 67-72 10.1111/j.1365-2826.2006.01505.x |
| 2007 | Duffield,J, Vuocolo,T, Tettam,R, Yuen,B, Muhlhauster,B, McMillen,I, 2007, Placental insufficiency reduces the expression of leptin and IGF1 mRNA in the perirenal adipose tissue of fetal sheep: a mechanism for altered fat development and obesity, EARLY HUMAN DEVELOPMENT, 83, S159-S159 10.1016/S0378-3782(07)70441-3 |
| 2007 | Muhlhausler,B, Duffield,J, McMillen,I, 2007, Increased maternal nutrition stimulates peroxisome proliferator activated receptor-γ, adiponectin, and leptin messenger ribonucleic acid expression in adipose tissue before birth, Endocrinology, 148, 2, 878-885 10.1210/en.2006-1115 |
| 2006 | MacLaughlin,S, Muhlhausler,B, Gentili,S, McMillen,I, 2006, When in gestation do nutritional alterations exert their effects? A focus on the early origins of adult disease, Current Opinion in Endocrinology, Diabetes and Obesity, 13, 6, 516-522 10.1097/MED.0b013e328010ca30 |
| 2006 | Muhlhausler,B, Adam,C, Findlay,P, Duffield,J, McMillen,I, 2006, Increased maternal nutrition alters development of the appetite-regulating network in the brain, The FASEB Journal, 20, 8, 1257-1259 10.1096/fj.05-5241fje |
| 2006 | McMillen,I, Edwards,L, Duffield,J, Muhlhausler,B, 2006, Regulation of leptin synthesis and secretion before birth: implications for the early programming of adult obesity, Reproduction, 131, 3, 415-427 10.1530/rep.1.00303 |
| 2005 | McMillen,I, Adam,C, Muhlhausler,B, 2005, Early origins of obesity: programming the appetite regulatory system, Journal of Physiology-London, 565, 1, 9-17 10.1113/jphysiol.2004.081992 |
| 2005 | Muhlhausler,B, Mühlhäusler,P, 2005, Simple English in the South Seas Evangelical Mission: Social context and linguistic attributes, Language Problems and Language Planning, 29, 1, 1-30 10.1075/lplp.29.1.02muh |
| 2005 | Muhlhausler,B, Adam,C, Marrocco,E, Findlay,P, Roberts,C, McFarlane,J, Kauter,K, McMillen,I, 2005, Impact of glucose infusion on the structural and functional characteristics of adipose tissue and on hypothalamic gene expression for appetite regulatory neuropeptides in the sheep fetus during late gestation, Journal of Physiology-London, 565, 1, 185-195 10.1113/jphysiol.2004.079079 |
| 2004 | McMillen,I, Muhlhausler,B, Duffield,J, Yuen,B, 2004, Prenatal programming of postnatal obesity: fetal nutrition and the regulation of leptin synthesis and secretion before birth, Proceedings of the Nutrition Society, 63, 3, 405-412 10.1079/PNS2004370 |
| 2004 | Muhlhausler,B, McMillen,I, Rouzad,G, Findlay,P, Marrocco,E, Rhind,S, Adam,C, 2004, Appetite regulatory neuropeptides are expressed in the sheep hypothalamus before birth, Journal of Neuroendocrinology, 16, 6, 502-507 10.1111/j.1365-2826.2004.01197.x |
| 2003 | Muhlhausler,B, 2003, The "big picture" in obesity research, Science, 300, 5622, 1091-1092 10.1126/science.300.5622.1091d |
| 2003 | Muhlhausler,B, Roberts,C, Yuen,B, Marrocco,E, Budge,H, Symonds,M, McFarlane,J, Kauter,K, Stagg,P, Pearse,J et al, 2003, Determinants of fetal leptin synthesis, fat mass, and circulating leptin concentrations in well-nourished ewes in late pregnancy, Endocrinology, 144, 11, 4947-4954 10.1210/en.2003-0555 |
| 2003 | Yuen,B, Owens,P, Muhlhausler,B, Roberts,C, Symonds,M, Keisler,D, McFarlane,J, Kauter,K, Evens,Y, McMillen,I et al, 2003, Leptin alters the structural and functional characteristics of adipose tissue before birth, FASEB Journal, 17, 6, www 1-www 22 10.1096/fj.02-0756fje |
| 2002 | Muhlhausler,B, Roberts,C, McFarlane,J, Kauter,K, McMillen,I, 2002, Fetal leptin is a signal of fat mass independent of maternal nutrition in ewes fed at or above maintenance energy requirements, Biology of Reproduction, 67, 2, 493-499 10.1095/biolreprod67.2.493 |
Book Chapters
| Date | Citation |
|---|---|
| 2016 | Muhlhausler,BS, Gugusheff,J, 2016, Prenatal programming of the mesolimbic reward pathway and food preferences, Springer, New York, pp. 169-188 10.1007/978-1-4939-3014-2_8 |
| 2012 | Mühlhäusler,BS, 2012, Roles of Pancreatic Cell Functions, Liver, Skeletal Muscle, and Adipose Tissues in Diabetes and Metabolic Syndrome, pp. 279-288 10.1016/B978-0-12-385083-6.00022-X |
| 2009 | McMillen,I, Rattanatray,L, Duffield,J, Morrison,J, MacLaughlin,S, Gentili,S, Muhlhausler,B, 2009, The early originis of later obesity: pathways and mechanisms, Springer, Dordrecht, Netherlands, pp. 71-82 10.1007/978-1-4020-9173-5_8 |
| 2009 | Mühlhausler,BS, 2009, Nutritional models of type 2 diabetes mellitus, Springer, pp. 19-36 10.1007/978-1-59745-448-3_2 |
| 2006 | McMillen,I, Duffield,J, Muhlhausler,B, 2006, Prenatal programming of postnatal obesity, Taylor & Francis, United Kingdom, pp. 73-83 |
Conference Papers
| Date | Citation |
|---|---|
| 2011 | Vithayathil,MA, Ong,ZY, Muhlhausler,BS, 2011, The Effects of Maternal High Fat Feeding on Body Fat Mass and Susceptibility to Diet Induced Obesity Can Be Reversed by Interventions during the Suckling Period |
| 2011 | Gugescheff,J, Morrison,JL, McMillen,CI, Muhlhausler,BS, 2011, Prenatal Activation of PPAR gamma Stimulates NPY Expression in the Fetal Hypothalamus and Promotes Milk Intake in the Lamb |
| 2011 | Ong,ZY, Muhlhausler,B, 2011, The Role of mu-Opioid Receptors in the Regulation of Macronutrient Preferences and Body Weight Gain |
| 2011 | Ong,ZY, Muhlhausler,BS, 2011, Reversing the Effects of Maternal High-Fat, High-Sugar Feeding on Offspring Food Preferences and Fat Deposition |
| 2010 | Nicholas,L, Rattanatray,L, McLaughlin,S, Muhlhausler,B, Kleeman,D, Walker,S, McMillen,C, 2010, Periconceptional Overnutrition and Offspring Gender Influences Hepatic Expression of Metabolic Genes in Postnatal Lamb., 57th Annual Meeting of the Society-for-Gynecologic-Investigation, Orlando, FL |
| 2010 | Rattanatray,L, MacLaughlin,SM, Muhlhausler,BS, Kleemann,D, Walker,S, McMillen,JC, 2010, Periconceptional Overnutrition Results in an Increase in Fat Mass in Female Offspring; the Role of Adipogenic and Lipogenic Genes, 57th Annual Meeting of the Society-for-Gynecologic-Investigation, Orlando, FL |
| 2010 | Nicholas,L, Rattanatray,L, McLaughlin,S, Muhlhausler,B, Kleeman,D, Walker,S, Morrison,J, McMillen,C, 2010, Maternal Overnutrition in the Periconceptional Period Results in Altered Expression of Hepatic Metabolic Genes in the Postnatal Lamb, 57th Annual Meeting of the Society-for-Gynecologic-Investigation, Orlando, FL |
| 2010 | Zhang,S, Rattanatray,L, MacLaughlin,SM, Cropley,JE, Suter,CM, Molloy,L, Kleemann,D, Walker,SK, Muhlhausler,BS, Morrison,JL et al, 2010, Increased Adrenal Growth and Decreased Methylation of the Adrenal Igf2/H19 Differentially Methylated Region after Exposure to Periconceptional Undernutrition., 57th Annual Meeting of the Society-for-Gynecologic-Investigation, Orlando, FL |
| 2009 | McMillen,C, Duffield,JA, Muhlhausler,BS, Rattanatray,L, Gentili,S, Morrison,JL, 2009, EARLY PATTERNS OF NUTRITION, GROWTH AND METABOLIC HEALTH |
| 2008 | Rattanatray,L, Muhlhausler,BS, McMillen,IC, 2008, Maternal overnutrition does not upregulate hepatic 11 beta HSD1 mRNA expression of the fetal and postnatal lamb., 55th Annual Meeting of the Society-for-Gynecologic-Investigation, San Diego, CA |
| 2008 | Muhlhausler,B, Duffield,J, Morrison,J, McMillen,I, 2008, Intrauterine growth restriction increases myocellular expression of PGC-1 alpha in male lambs in early postnatal life, 55th Annual Meeting of the Society-for-Gynecologic-Investigation, San Diego, CA |
| 2007 | Muhlhausler,B, Duffield,J, Morrison,J, McMillen,I, 2007, Placental restriction and the expression of AMPK in adipose tissue in the late gestation fetal sheep 10.1016/S0378-3782(07)70451-6 |
| 2005 | Duffield,J, Tellam,R, Vuocolo,T, McFarlane,J, Kanter,K, Muhlhausler,B, McMillen,I, 2005, Impact of low birth weight and gender on PPAR7, leptin and adiponectin expression in the subcutaneous fat of lambs, Experimental Biology 2005 Meeting/35th International Congress of Physiological Sciences, San Diego, CA |
| 2005 | Muhlhausler,B, Adam,B, Findlay,P, Duffield,J, McMillen,I, 2005, Increased maternal nutrition increases hypothalamic expression of the appetite inhibitor proopiomelanocortin in the postnatal lamb, 3rd International Congress on Developmental Origins of Health and Disease, Toronto, CANADA |
| 2005 | Duffield,J, Vuocolo,T, Tellam,R, McFarlane,J, Kauter,K, Muhlhausler,B, McMillen,I, 2005, Differential impact of low birth weight on PPAR gamma and leptin expression in perirenal fat in male and female lambs., 52nd Annual Meeting of the Society-for-Gynecologic-Investigation, Los Angeles, CA |
| 2005 | Muhlhausler,B, Duffield,J, McMillen,I, 2005, Maternal overnutrition in late gestation increases peripheral fat deposition in the postnatal lamb, Experimental Biology 2005 Meeting/35th International Congress of Physiological Sciences, San Diego, CA |
| 2004 | Muhlhausler,B, Adam,C, Findlay,P, Marrocco,E, McMillen,I, 2004, Glucose increases the expression of POMC mRNA in the hypothalamus of the fetal sheep in late gestation., 51st Annual Meeting of the Society-for-Gynecologic-Investigation, Houston, TX |
| 2003 | Muhlhausler,B, Schultz,C, Chatterton,B, McMillen,I, 2003, Adiposity is positively correlated with weight gain over the first 6 months of postnatal life in female sheep, 2nd World Congress on Dietal Origins of Adult Disease, BRIGHTON, ENGLAND |
Conference Items
| Date | Citation |
|---|---|
| 2017 | Gatford,KL, Muhlhausler,BS, Sim,PS-L, Roberts,CT, Veldhuis,JD, Huang,L, Chen,C, 2017, Pulsatile GH profiles in the pregnant mouse reveal marked increases in circulating GH and GH secretion between early and mid-pregnancy |
| 2011 | Fong,L, Muhlhausler,B, Gibson,RA, Xian,CJ, 2011, Effects of maternal dietary supplementation of omega-3 fatty acids during pregnancy and lactation on offspring's bone growth and adult bone mass, 3rd Joint Meeting of the European Calcified Tissue Society/International Bone and Mineral Society (ECTS 2011) (IBMS), Athens, Greece 10.1016/j.bone2011.03.376 |
| 2009 | Muhlhausler,BSCJ, James,M, Duthroit,E, Gibson,RA, 2009, Dietary balance of omega-3 and omega-6 PUFA controls expression of lipogenic genes, 19th International Congress of Nutrition, Bangkok, Thailand 10.1159/000248280 |
|
Year |
Granting Body |
Title
|
Name |
Amount |
|
2015 |
The University of Adelaide DVCR Interdisciplinary Research Fund (IRF) |
Consumer perceptions, sensory appeal and nutritional value of edible insects: realising the potential of an emerging agricultural industry. |
Wilkinson K, Muhlhausler BS, Ankeny R, Bray H |
$25,000 |
|
2015-2018 |
NHMRC Career Development Award (Level 2) |
Breaking the Intergenerational Cycle of Obesity through Nutritional Interventions |
Muhlhausler BS |
$455,113 |
|
2015-2016 |
Diabetes Australia Research Trust |
Early Epigenetic Predictors of Insulin Resistance |
Muhlhausler BS, Molloy P, VanDijk S, Buckley M, Makrides M |
$60,000 |
|
2013 |
Waite Research Institute |
How Do Nutrients Regulate the Microbiome-Genome Interactions in the Maturing GI tract of Preterm Infants |
Muhlhausler BS, McPhee A, Collins CT, Gibson RA, Makrides M, Penttila , Bianco-Miotto T, Bent S |
$70,000 |
|
2013-2016 |
Premier’s Research and Industry Fund |
Improving the efficacy of sustainable plant oils to increased omega-3 levels in chicken products |
Gibson RA, Hughes B, Hynd P, Muhlhausler B |
$150,000 |
|
2013-2014 |
Channel 7 Children’s Health Research Foundation |
Low GI diets for improving metabolic outcomes |
Muhlhausler B, Brand-Miller J, Gentili S |
$70,000 |
|
2012-2016 |
NHMRC Centre of Research Excellence Foods for Future Australians |
Foods for Future Australians |
Makrides M, Gibson RA, Ryan P, Zhou SJ, Dodd J, McPhee AJ, Umberger W, Muhlhausler B, Collins CT, Penttila I |
$2,500,000 |
|
2011-2014 |
SIEF (Science & Industry Endowment Fund)
|
Early Nutrition, the Epigenome and the Prevention of Disease
|
Molloy P, Tellam P, Ryan L, Clark S, Samaras K, Cooney GJ, Makrides M, Muhlhausler B, McMillen C, Morrison J, Noakes M. |
$2,000,000 |
|
2011 |
NHMRC Equipment Grant |
The BOD-POD: A state-of-the-art system for measuring body composition |
Couper J, Makrides M, Gibson RA, Dodd J, Muhlhausler BS, Collins CT, McPhee A |
$65,000 |
|
2011-2014 |
NHMRC Career Development Award |
Better nutrition for mothers and infants for healthier Australians |
Muhlhausler B |
$384,160 |
|
2010-2012 |
NHMRC Project Grant |
Nutrition Before Conception and Later Obesity |
McMillen C, Morrison J, Muhlhausler B, Ozanne S |
$434,150 |
|
2009-2013 |
NHMRC Project Grant |
The Childhood Obesity and Insulin Resistance Prevention Study (ChOIR) |
Makrides, Muhlhausler, Gibson, McDermott, Tapsell |
$1,380,000 |
|
2007-2009 |
NHMRC Project Grant |
The EarlyOrigins Of Obesity |
McMillen IC & Muhlhausler BS |
$320,250 |
|
2009-2011 |
Channel 7 Children’s Health Research Foundation
|
Blocking the Early Origins of Obesity: A Role for Omega-3 fatty acids? |
Muhlhausler B, Gibson RA |
$100,000 |
|
2009 |
The Clive & Vera Ramaciotti Establishment Grant |
Early Origins of A Taste for Fat: A New Perspective on the Early Life Origins of Obesity |
Muhlhausler B |
$29,000 |
|
2009 |
UniSA Health Sciences Divisional Research Grant |
Blocking the Early Origins of Obesity: A Role for Omega-3 fatty acids? |
Muhlhausler B |
$10,000 |
|
2007-2011 |
NHMRC Peter Doherty Post Doctoral Fellowship |
The Early Origins of Obesity: A Population Based and Mechanistic Approach |
Muhlhausler B |
$269,000 |
|
2007-2008 |
Channel 7 Children’s Research Foundation Grant |
Intrauterine Growth Restriction and the Early Origins of the Metabolic Syndrome |
Muhlhausler B |
$40,000 |
Current PhD Students
- Gabriela Esteves Leghi
- See Meng Lim
- Chloe Douglas
- Nina Wilson
- Khaled Kanakri
- Erandi Hewawasam
- Samantha Chown
- Shannon Hunt
- Sally Draycott
Past PhD Students
- Katie Wood (2016)
- Carla Toop (2016)
- Dao Huynh (2015)
- Mini Vithayathil (2015)
- Jessica Gugusheff (2015)
- Maryam Bazargan (2015)
- Liu Ge (2014)
Current Honours Students
- Jonothan Wurst
Committee Memberships
| Date | Role | Committee | Institution | Country |
|---|---|---|---|---|
| 2017 | President | Australia and New Zealand Society for the Developmental Origins of Health and Disease (DOHaD) | Australia | |
| 2014 | Secretary | Australia New Zealand Society for the Developmental Origins of Health and Disease | Australia |
Position
Senior Research Fellow
Phone
83130848
Fax
8313 7135
Campus
Waite
Building
Waite Building
Room Number
GS 20
Org Unit
School of Agriculture, Food and Wine