Bella Van Sebille

APrf Bella Van Sebille

Associate Dean, Adelaide University Online

Adelaide University Online and Learning Futures

Academic

Bella is the Program Facilitator for the Bachelor of Health Sciences, the Bachelor of Nutrition and Exercise and the Diploma of Health for UniSA Online.
Bella's PhD in Medicine centred around understanding the physiological mechanisms of gastrointestinal toxicity arising from new cancer treatments (ErbB Targeted Therpaies). Her research now sits at the intersection of supportive oncology (management of cancer treatment side effects) and digital health, with a vision to harness digital health innovations to enable the provision of personalised, proactive, and efficient cancer care.
Bella is widely published, with her work cited 148% more than the world average. She is an internationally recognised expert in oncology, digital health and higher education. Bella is regularly invited to present her work internationally, and has delivered several international workshops and webinars on digital health in oncology. Bella is the chair of the international Digital Health and New Technologies Study Group for the Multinational Association of Supportive Care in Cancer where she sets international standards for digital health literacy in cancer care. Her focus on improving real-world care and outcomes directly informs the way she designs and leads curriculum, embedding cutting-edge digital health innovations and models of care principles into teaching that is evidence-based, clinically relevant, and globally aligned.
Learn more about her here: https://youtu.be/pHPWj-9_Myk 

Year Citation
2025 Van Sebille, Y., Short, C. E., Howell, D., & Bender, J. L. (2025). Optimizing the impact of supportive cancer care digital health interventions: considerations for design, development, and evaluation. Supportive Care in Cancer, 33(11), 10 pages.
DOI
2025 Van Sebille, Y., Wishart, L. R., & Bender, J. L. (2025). Standards and practice recommendations for Telehealth in Oncology: MASCC endorsed practice recommendations developed by the American Society of Clinical Oncology. Supportive Care in Cancer, 33(8), 4 pages.
DOI Scopus1 WoS1 Europe PMC1
2024 Wang, Y., Allsop, M. J., Epstein, J. B., Howell, D., Rapoport, B. L., Schofield, P., . . . van den Hurk, C. J. G. (2024). Patient-reported symptom monitoring: using (big) data to improve supportive care at the macro-, meso-, and micro-levels. Supportive Care in Cancer, 32(3), 6 pages.
DOI Scopus1 WoS2 Europe PMC1
2024 Abdalla-Aslan, R., Bonomo, P., Keefe, D., Blijlevens, N., Cao, K., Cheung, Y. T., . . . Nagano, C. (2024). Guidance on mucositis assessment from the MASCC Mucositis Study Group and ISOO: an international Delphi study. eClinicalMedicine, 73(102675), 102675-1-102675-12.
DOI Scopus8 WoS9 Europe PMC7
2024 Chan, R. J., Knowles, R., Ashbury, F. D., Bowen, J., Chan, A., Chin, M., . . . Lustberg, M. (2024). Supportive care 2030 movement: towards unifying ambitions for global excellence in supportive cancer care—an international Delphi study. EClinicalMedicine, 76, 102825-1-102825-12.
DOI Scopus13 WoS12 Europe PMC8
2023 Al-Qadami, G., Bowen, J., Van Sebille, Y., Secombe, K., Dorraki, M., Verjans, J., . . . Le, H. (2023). Baseline gut microbiota composition is associated with oral mucositis and tumour recurrence in patients with head and neck cancer: a pilot study. Supportive Care in Cancer, 31(1), 98-1-98-14.
DOI Scopus25 WoS24 Europe PMC22
2022 Gabriel, F., Marrone, R., Van Sebille, Y., Kovanovic, V., & de Laat, M. (2022). Digital education strategies around the world: practices and policies. Irish Educational Studies, 41(1), 85-106.
DOI Scopus57 WoS27
2022 Al-Qadami, G., Van Sebille, Y., Bowen, J., & Wardill, H. (2022). Oral-Gut Microbiome Axis in the Pathogenesis of Cancer Treatment-Induced Oral Mucositis.. Frontiers in Oral Health, 3, 881949-1-881949-10.
DOI Scopus31 WoS30 Europe PMC23
2022 Al-Qadami, G., Verma, G., Van Sebille, Y., Le, H., Hewson, I., Bateman, E., . . . Bowen, J. (2022). Antibiotic-Induced Gut Microbiota Depletion Accelerates the Recovery of Radiation-Induced Oral Mucositis in Rats.. International Journal of Radiation: Oncology- Biology- Physics, 113(4), 845-858.
DOI Scopus15 WoS16 Europe PMC15
2022 Dixit, N., Van Sebille, Y., Crawford, G. B., Ginex, P. K., Ortega, P. F., & Chan, R. J. (2022). Disparities in telehealth use: How should the supportive care community respond?. Supportive Care in Cancer, 30(2), 1007-1010.
DOI Scopus54 WoS48 Europe PMC42
2021 Secombe, K. R., Al-Qadami, G. H., Subramaniam, C. B., Bowen, J. M., Scott, J., Van Sebille, Y. Z. A., . . . Wardill, H. R. (2021). Guidelines for reporting on animal fecal transplantation (GRAFT) studies: recommendations from a systematic review of murine transplantation protocols. Gut Microbes, 13(1), 1979878-1-1979878-15.
DOI Scopus65 WoS60 Europe PMC56
2020 Secombe, K. R., Van Sebille, Y. Z. A., Mayo, B. J., Coller, J. K., Gibson, R. J., & Bowen, J. M. (2020). Diarrhea Induced by Small Molecule Tyrosine Kinase Inhibitors Compared With Chemotherapy: Potential Role of the Microbiome.. Integrative Cancer Therapies, 19, 1534735420928493-1-153473542092849-12.
DOI Scopus58 WoS54 Europe PMC50
2020 Wardill, H. R., Sonis, S. T., Blijlevens, N. M. A., Van Sebille, Y. Z. A., Ciorba, M. A., Loeffen, E. A. H., . . . Mucositis Study Group of the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO). (2020). Prediction of mucositis risk secondary to cancer therapy: a systematic review of current evidence and call to action. Support Care Cancer, 28(11), 5059-5073.
DOI Scopus68 WoS61 Europe PMC49
2020 Elad, S., Cheng, K. K. F., Lalla, R. V., Yarom, N., Hong, C., Logan, R. M., . . . Zur, E. (2020). MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Cancer, 126(19), 4423-4431.
DOI Scopus536 WoS506 Europe PMC361
2019 Al-Qadami, G., Van Sebille, Y., Le, H., & Bowen, J. (2019). Gut microbiota: implications for radiotherapy response and radiotherapy-induced mucositis. Expert Review of Gastroenterology and Hepatology, 13(5), 485-496.
DOI Scopus66 WoS59 Europe PMC54
2019 Van Sebille, Y. Z., Gibson, R. J., Wardill, H. R., Carney, T. J., & Bowen, J. M. (2019). Use of zebrafish to model chemotherapy and targeted therapy gastrointestinal toxicity.. Experimental biology and medicine (Maywood, N.J.), 244(14), 1178-1185.
DOI Scopus18 WoS17 Europe PMC13
2019 Bowen, J. M., Gibson, R. J., Coller, J. K., Blijlevens, N., Bossi, P., Al-Dasooqi, N., . . . Elad, S. (2019). Systematic review of agents for the management of cancer treatment-related gastrointestinal mucositis and clinical practice guidelines. Supportive Care in Cancer, 27(10), 4011-4022.
DOI Scopus75 WoS60 Europe PMC46
2019 Bowen, J., Al-Dasooqi, N., Bossi, P., Wardill, H., Van Sebille, Y., Al-Azri, A., . . . Elad, S. (2019). The pathogenesis of mucositis: updated perspectives and emerging targets. Supportive Care in Cancer, 27(10), 4023-4033.
DOI Scopus144 WoS124 Europe PMC100
2018 Van Sebille, Y., Gibson, R., Wardill, H., Ball, I., Keefe, D., & Bowen, J. (2018). Dacomitinib-induced diarrhea: Targeting chloride secretion with crofelemer. International Journal of Cancer, 142(2), 369-380.
DOI Scopus16 WoS15 Europe PMC16
2018 Wardill, H. R., Van Sebille, Y. Z. A., Ciorba, M. A., & Bowen, J. M. (2018). Prophylactic probiotics for cancer therapy-induced diarrhoea: A meta-analysis. Current Opinion in Supportive and Palliative Care, 12(2), 187-197.
DOI Scopus55 WoS53 Europe PMC47
2018 Gibson, R. J., Van Sebille, Y. Z. A., Wardill, H. R., Wignall, A., Shirren, J., Ball, I. A., . . . Bowen, J. M. (2018). Selective MMP inhibition, using AZD3342, to reduce gastrointestinal toxicity and enhance chemoefficacy in a rat model. Chemotherapy, 63(5), 284-292.
DOI Scopus5 WoS5 Europe PMC2
2017 Coller, J. K., Bowen, J. M., Ball, I. A., Wardill, H. R., Van Sebille, Y. Z. A., Stansborough, R. L., . . . Gibson, R. J. (2017). Potential safety concerns of TLR4 antagonism with irinotecan: a preclinical observational report. Cancer Chemotherapy and Pharmacology, 79(2), 431-434.
DOI Scopus9 WoS8 Europe PMC8
2017 Wardill, H., Bowen, J., Van Sebille, Y., & Gibson, R. (2017). Routine assessment of the gut microbiome to promote preclinical research reproducibility and transparency. Gut, 66(10), 1869-1871.
DOI Scopus3 WoS3 Europe PMC2
2017 Van Sebille, Y., Gibson, R., Wardill, H., Secombe, K., Ball, I., Keefe, D., . . . Bowen, J. (2017). Dacomitinib-induced diarrhoea is associated with altered gastrointestinal permeability and disruption in ileal histology in rats. International Journal of Cancer, 140(12), 2820-2829.
DOI Scopus33 WoS29 Europe PMC30
2016 Wardill, H., Logan, R., Bowen, J., Van Sebille, Y., & Gibson, R. (2016). Tight junction defects are seen in the buccal mucosa of patients receiving standard dose chemotherapy for cancer. Supportive Care in Cancer, 24(4), 1779-1788.
DOI Scopus18 WoS18 Europe PMC16
2016 Wardill, H., Gibson, R., Van Sebille, Y., Secombe, K., Logan, R., & Bowen, J. (2016). A novel in vitro platform for the study of SN38-induced mucosal damage and the development of Toll-like receptor 4-targeted therapeutic options. Experimental Biology and Medicine, 241(13), 1386-1394.
DOI Scopus8 WoS7 Europe PMC8
2016 Van Sebille, Y., Gibson, R., Wardill, H., & Bowen, J. (2016). Gastrointestinal toxicities of first and second-generation small molecule human epidermal growth factor receptor tyrosine kinase inhibitors in advanced nonsmall cell lung cancer. Current Opinion in Supportive and Palliative Care, 10(2), 152-156.
DOI Scopus7 WoS6 Europe PMC5
2016 Wardill, H., Gibson, R., Van Sebille, Y., Secombe, K., Coller, J., White, I., . . . Bowen, J. (2016). Irinotecan-induced gastrointestinal dysfunction and pain are mediated by common TLR4-dependent mechanisms. Molecular Cancer Therapeutics, 15(6), 1376-1386.
DOI Scopus124 WoS115 Europe PMC103
2016 Wardill, H., Mander, K., Van Sebille, Y., Gibson, R., Logan, R., Bowen, J., & Sonis, S. (2016). Cytokine-mediated blood brain barrier disruption as a conduit for cancer/chemotherapy-associated neurotoxicity and cognitive dysfunction. International Journal of Cancer, 139(12), 2635-2645.
DOI Scopus144 WoS124 Europe PMC116
2016 Wardill, H., Bowen, J., Van Sebille, Y., Secombe, K., Coller, J., Ball, I., . . . Gibson, R. (2016). TLR4-dependent claudin-1 internalization and secretagogue-mediated chloride secretion regulate irinotecan-induced diarrhea. Molecular Cancer Therapeutics, 15(11), 2767-2779.
DOI Scopus45 WoS41 Europe PMC31
2015 Wardill, H., Van Sebille, Y., Mander, K., Gibson, R., Logan, R., Bowen, J., & Sonis, S. (2015). Toll-like receptor 4 signaling: a common biological mechanism of regimen-related toxicities an emerging hypothesis for neuropathy and gastrointestinal toxicity. Cancer Treatment Reviews, 41(2), 122-128.
DOI Scopus34 WoS32 Europe PMC28
2015 Wardill, H. R., Van Sebille, Y. Z., Bowen, J. M., & Gibson, R. J. (2015). Editorial comment: does gut-derived inflammation enhance pain signaling following chemotherapy in a Toll-like receptor 4-dependent manner?. Current Opinion in Supportive and Palliative Care, 9(2), 155-156.
DOI Scopus1 WoS1
2015 Van Sebille, Y., Gibson, R., Wardill, H., & Bowen, J. (2015). ErbB small molecule tyrosine kinase inhibitor (TKI) induced diarrhoea: chloride secretion as a mechanistic hypothesis. Cancer Treatment Reviews, 41(7), 646-652.
DOI Scopus57 WoS52 Europe PMC39
2015 Van Sebille, Y., Stansborough, R., Wardill, H., Bateman, E., Gibson, R., & Keefe, D. (2015). Management of mucositis during chemotherapy: from pathophysiology to pragmatic therapeutics. Current Oncology Reports, 17(11), 50-1-50-8.
DOI Scopus73 WoS62 Europe PMC48

Year Citation
2020 Al-Qadami, G., Van Sebille, Y., Hien, L., Hewson, I., & Bowen, J. (2020). Antibiotic-induced depletion of gut microbiota: Impact on radiation-induced oral mucositis in rats. Poster session presented at the meeting of NEUROGASTROENTEROLOGY AND MOTILITY. WILEY.
2019 Al-Qadami, G., Van Sebille, Y., Le, H., Hewson, I., & Bowen, J. (2019). Antibiotic-induced depletion of gut microbiota: Impact on radiation-induced oral mucositis in rats. Poster session presented at the meeting of ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY. WILEY.

Courses I teach

  • HLTH 1068 UO Introduction to Human Physiology (2025)

Date Role Research Topic Program Degree Type Student Load Student Name
2019 - 2021 External Supervisor Exploring the Role of the Gut Microbiome in Toxicity and Response to Radiotherapy for Head and Neck Cancer Doctor of Philosophy Doctorate Full Time Mrs Ghanyah Hamid Hussein Al-Qadami

Connect With Me

External Profiles

Other Links