Belinda Di Bartolo
Adelaide Medical School
Faculty of Health and Medical Sciences
Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.
Belinda completed her PhD in 2009 at the Heart Research Institute in Sydney. In 2011 she was awarded an NHMRC Early Career Training Fellowship to undertake research at the Centre for Vascular Research. Belinda joined SAHMRI mid-way through 2015 as a Senior Post Doctoral Fellow and her current research interests include the effect of lipids and lipid-lowering therapies on the process of vascular inflammation and calcification in heart disease and diabetes. She currently leads the Vascular Inflammation group in the Heart Health Theme at SAHMRI.
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Appointments
Date Position Institution name 2015 Afflliate University of Adelaide 2015 Senior Post Doctoral Fellow South Australian Health and Medical Research Institute, Adelaide 2014 - 2015 Affiliate University of Sydney, Sydney 2014 - 2015 Senior Post Doctoral Researcher The Heart Research Institute 2009 - 2014 Post Doctoral Researcher The University of New South Wales -
Awards and Achievements
Date Type Title Institution Name Country Amount 2017 Award Tom Simpson Trust Fund Award Heart Foundation — — 2017 Award Australian Atherosclerosis Society Trust Award — — — 2015 Award ATVB Junior Investigator for Women Finalist — — — 2014 Award ATVB Young Investigator Finalist American Heart Association — — 2014 Award Best Post Doctoral Poster Presentation ISCP State of the Heart – Australian Vascular Biology Society — — 2013 Award Best Poster Award European Atherosclerosis Society — — 2012 Award Best Post Doctoral Poster Presentation Australian Vascular Biology Society — — 2012 Fellowship Early Career Fellowship – Peter Doherty Award NHMRC — — 2011 Award Post Doctoral Travel Award University of New South Wales — — 2011 Award Young Investigator Award Asia-Pacific Society of Atherosclerosis and Vascular Diseases (APSAVD) Congress — — 2011 Award Best Post Doctoral Oral presentation Australian Vascular Biology Society — — 2010 Award BioAssayLINK Award Australian Atherosclerosis Society — — 2010 Award Young Investigator Award Australian Atherosclerosis Society — — 2010 Award Post Doctoral Travel Award University of New South Wales — — 2009 Award Young Investigator Award XV International Symposium on Atherosclerosis — — 2009 Award Student Travel Award National Heart Foundation, Australia — — 2009 Award Student Travel Award Australian Atherosclerosis Society — — -
Language Competencies
Language Competency English Can read, write, speak, understand spoken and peer review -
Education
Date Institution name Country Title 2006 - 2009 University of Sydney, Sydney Australia PhD — University of Sydney, Sydney Australia BMedSc -
Research Interests
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Journals
Year Citation 2019 Takata, K., Honda, S., Sidharta, S., Duong, M., Shishikura, D., Kim, S., . . . Nicholls, S. (2019). Associations of ABCG1-mediated cholesterol efflux capacity with coronary artery lipid content assessed by near-infrared spectroscopy. Cardiovascular Diagnosis and Therapy, 9(4), 310-318.
2019 Toledo-Flores, D., Williamson, A., Schwarz, N., Fernando, S., Dimasi, C., Witt, T., . . . Psaltis, P. (2019). Vasculogenic properties of adventitial Sca-1+CD45+ progenitor cells in mice: a potential source of vasa vasorum in atherosclerosis. Scientific Reports, 9(1), 15 pages.
WoS12019 Akers, E. J., Nicholls, S. J., & Di Bartolo, B. A. (2019). Plaque Calcification.. Arteriosclerosis, thrombosis, and vascular biology, ATVBAHA119311574.
2018 Cannizzo, C., Adonopulos, A., Solly, E., Ridiandries, A., Vanags, L., Mulangala, J., . . . Tan, J. (2018). VEGFR2 is activated by high-density lipoproteins and plays a key role in the proangiogenic action of HDL in ischemia. FASEB Journal, 32(6), 2911-2922.
Scopus3 WoS32018 Takata, K., Di Bartolo, B., & Nicholls, S. (2018). High-Density Lipoprotein Infusions. Cardiology Clinics, 36(2), 311-315.
Scopus12018 Andrews, J., Psaltis, P., Bartolo, B., Nicholls, S., & Puri, R. (2018). Coronary arterial calcification: A review of mechanisms, promoters and imaging. Trends in Cardiovascular Medicine, 28(8), 491-501.
Scopus5 WoS6 Europe PMC22018 Di Bartolo, B., & Straub, A. (2018). Highlights from vascular discovery: From genes to medicine scientific sessions 2018. Journal of the American Heart Association, 7(15), 3 pages.
2018 Di Bartolo, B., Psaltis, P., Bursill, C., & Nicholls, S. (2018). Translating evidence of HDL and plaque regression. Arteriosclerosis, thrombosis, and vascular biology, 38(9), 1961-1968.
Scopus1 WoS12017 Di Bartolo, B., Schwarz, N., Andrews, J., & Nicholls, S. (2017). Infusional high-density lipoproteins therapies as a novel strategy for treating atherosclerosis. Archives of Medical Science, 13(1), 210-214.
Scopus2 WoS2 Europe PMC12017 Di Bartolo, B., Scherer, D., Brown, A., Psaltis, P., & Nicholls, S. (2017). PCSK9 Inhibitors in Hyperlipidemia: Current Status and Clinical Outlook. BioDrugs, 31(3), 167-174.
Scopus4 WoS4 Europe PMC22017 Cartland, S., Harith, H., Genner, S., Dang, L., Cogger, V., Vellozzi, M., . . . Kavurma, M. (2017). Non-alcoholic fatty liver disease, vascular inflammation and insulin resistance are exacerbated by TRAIL deletion in mice. Scientific Reports, 7(1), 1898-1-1898-12.
Scopus16 WoS15 Europe PMC72017 Di Bartolo, B., & Nicholls, S. (2017). Anacetrapib as a potential cardioprotective strategy. Drug Design, Development and Therapy, 11, 3497-3502.
Scopus2 WoS22016 Di Bartolo, B., Scherer, D., & Nicholls, S. (2016). Inducing apolipoprotein A-I synthesis to reduce cardiovascular risk: From ASSERT to SUSTAIN and beyond. Archives of Medical Science, 12(6), 1302-1307.
Scopus9 WoS9 Europe PMC62016 Di Bartolo, B., Duong, M., & Nicholls, S. (2016). Clinical trials with cholesteryl ester transfer protein inhibitors. Current Opinion in Lipidology, 27(6), 545-549.
Scopus9 WoS8 Europe PMC52016 Di Bartolo, B., Takata, K., Duong, M., & Nicholls, S. (2016). CETP Inhibition in CVD prevention: an actual appraisal. Current Cardiology Reports, 18(5), 43-1-43-6.
Scopus10 WoS10 Europe PMC72016 Harith, H., Di Bartolo, B., Cartland, S., Genner, S., & Kavurma, M. (2016). Insulin promotes vascular smooth muscle cell proliferation and apoptosis via differential regulation of tumor necrosis factor-related apoptosis-inducing ligand. Journal of Diabetes, 8(4), 568-578.
Scopus4 WoS4 Europe PMC22015 Duong, M., Di Bartolo, B., & Nicholls, S. (2015). Acute high-density lipoprotein therapies. Current Opinion in Lipidology, 26(6), 521-525.
Scopus2 WoS22015 Di Bartolo, B., Cartland, S., Prado-Lourenco, L., Griffith, T., Gentile, C., Ravindran, J., . . . Kavurma, M. (2015). Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) promotes angiogenesis and ischemia-induced neovascularization via NADPH oxidase 4 (NOX4) and nitric oxide-dependent mechanisms. Journal of the American Heart Association, 4(11), e002527-1-e002527-16.
Scopus21 WoS20 Europe PMC102014 Di Bartolo, B., & Kavurma, M. (2014). Regulation and function of RANKL in arterial calcification. Current Pharmaceutical Design, 20(37), 5853-5861.
Scopus4 WoS4 Europe PMC12013 Di Bartolo, B., Cartland, S., Harith, H., Bobryshev, Y., Schoppet, M., & Kavurma, M. (2013). TRAIL-deficiency accelerates vascular calcification in atherosclerosis via modulation of RANKL. PLoS ONE, 8(9), e74211-1-e74211-9.
Scopus36 WoS33 Europe PMC192012 Azahri, N., Di Bartolo, B., Khachigian, L., & Kavurma, M. (2012). Sp1, acetylated histone-3 and p300 regulate TRAIL transcription: mechanisms of PDGF-BB-mediated VSMC proliferation and migration. Journal of Cellular Biochemistry, 113(8), 2597-2606.
Scopus25 WoS27 Europe PMC182011 Di Bartolo, B., Chan, J., Bennett, M., Cartland, S., Bao, S., Tuch, B., & Kavurma, M. (2011). TNF-related apoptosis-inducing ligand (TRAIL) protects against diabetes and atherosclerosis in Apoe -/- mice. Diabetologia, 54(12), 3157-3167.
Scopus74 WoS71 Europe PMC582011 Di Bartolo, B., Vanags, L., Tan, J., Bao, S., Rye, K., Barter, P., & Bursill, C. (2011). The apolipoprotein A-I mimetic peptide, ETC-642, reduces chronic vascular inflammation in the rabbit.. Lipids in health and disease, 10(1), 224.
Scopus18 WoS18 Europe PMC92011 Di Bartolo, B., Nicholls, S., Bao, S., Rye, K., Heather, A., Barter, P., & Bursill, C. (2011). The apolipoprotein A-I mimetic peptide ETC-642 exhibits anti-inflammatory properties that are comparable to high density lipoproteins. Atherosclerosis, 217(2), 395-400.
Scopus34 WoS36 Europe PMC272011 Di Bartolo, B., Schoppet, M., Mattar, M., Rachner, T., Shanahan, C., & Kavurma, M. (2011). Calcium and osteoprotegerin regulate IGF1R expression to inhibit vascular calcification. Cardiovascular Research, 91(3), 537-545.
Scopus26 WoS25 Europe PMC162010 Patel, S., Di Bartolo, B., Nakhla, S., Heather, A., Mitchell, T., Jessup, W., . . . Rye, K. (2010). Anti-inflammatory effects of apolipoprotein A-I in the rabbit. Atherosclerosis, 212(2), 392-397.
Scopus51 WoS52 Europe PMC442010 Chan, J., Prado-Lourenco, L., Khachigian, L., Bennett, M., Di Bartolo, B., & Kavurma, M. (2010). TRAIL promotes VSMC proliferation and neointima formation in a FGF-2-, Sp1 Phosphorylation-, and NFκB-Dependent Manner. Circulation Research, 106(6), 1061-1071.
Scopus56 WoS53 Europe PMC382009 Peshavariya, H., Dusting, G., Di Bartolo, B., Rye, K., Barter, P., & Jiang, F. (2009). Reconstituted high-density lipoprotein suppresses leukocyte NADPH oxidase activation by disrupting lipid rafts. Free Radical Research, 43(8), 772-782.
Scopus24 WoS22 Europe PMC152009 McGrath, K., Li, X., Puranik, R., Liong, E., Tan, J., Dy, V., . . . Heather, A. (2009). Role of 3β-hydroxysteroid-Δ24 reductase in mediating antiinflammatory effects of high-density lipoproteins in endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology, 29(6), 877-882.
Scopus61 WoS61 Europe PMC422006 Cutri, B., Hime, N., & Nicholls, S. (2006). High-density lipoproteins: An emerging target in the prevention of cardiovascular disease. Cell Research, 16(10), 799-808.
Scopus20 WoS20 Europe PMC122006 Nicholls, S., Lundman, P., Harmer, J., Cutri, B., Griffiths, K., Rye, K., . . . Celermajer, D. (2006). Consumption of saturated fat impairs the anti-inflammatory properties of high-density lipoproteins and endothelial function. Journal of the American College of Cardiology, 48(4), 715-720.
Scopus148 WoS133 Europe PMC902005 Nicholls, S., Cutri, B., Worthley, S., Kee, P., Rye, K., Bao, S., & Barter, P. (2005). Impact of short-term administration of high-density lipoproteins and atorvastatin on atherosclerosis in rabbits. Arteriosclerosis Thrombosis and Vascular Biology, 25(11), 2416-2421.
Scopus127 WoS121 Europe PMC882005 Nicholls, S., Dusting, G., Cutri, B., Bao, S., Drummond, G., Rye, K., & Barter, P. (2005). Reconstituted high-density lipoproteins inhibit the acute pro-oxidant and proinflammatory vascular changes induced by a periarterial collar in normocholesterolemic rabbits. Circulation, 111(12), 1543-1550.
Scopus225 WoS211 Europe PMC164 -
Conference Papers
Year Citation 2019 Pisaniello, A. D., King, P., Di Bartolo, B. A., Liu, G., Gibson, R. A., Tan, J. T., . . . Nicholls, S. (2019). IMPACT OF FISH OIL SUPPLEMENTATION ON ACUTE VASCULAR INFLAMMATION IN HEALTHY VOLUNTEERS. In JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol. 73 (pp. 2091). New Orleans, LA: ELSEVIER SCIENCE INC.
2019 Akers, E. J., Mulangala, J., Wilsdon, L. A., Psaltis, P. J., Bursill, C. A., Nicholls, S. J., & Di Bartolo, B. A. (2019). Lipoproteins and Their Modified Forms Regulate Early Stage Vascular Smooth Muscle Cell Calcification. In ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY Vol. 39 (pp. 2 pages). Boston, MA: LIPPINCOTT WILLIAMS & WILKINS. 2008 Di Bartolo, B. A., Bao, S., Rye, K. -A., Nicholls, S. J., & Barter, P. J. (2008). In vivo properties of a novel apolipoprotein A-1 mimetic peptide. In JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol. 51 (pp. A283). Chicago, IL: ELSEVIER SCIENCE INC.
2016 National Heart Foundation Ahrens Grant for 2016 $65000
2014 University of Sydney Early Career Research Grant $25000 for 2015
2011 NHMRC Early Career Fellowship – Peter Doherty Award 2012-2017
2011 University of New South Wales Post Doctoral Small Grant Program $10,000
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Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2017 Co-Supervisor Role of HDL in diabetes impaired angiogenesis and vascular calcification Doctor of Philosophy Doctorate Full Time Ms Jocelyne Mulangala 2017 Co-Supervisor The role of HDL in vascular calcification and atherosclerosis Doctor of Philosophy Doctorate Full Time Miss Emma Jill Akers 2017 Co-Supervisor The Impact of Omega-3 Fatty Acids on Inflammatory Pathways in the Vessell Wall and Adipose Tissue that Promote Cardiovascular Risk Doctor of Philosophy Doctorate Full Time Dr Anthony David Pisaniello
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