Belinda Di Bartolo

Belinda Di Bartolo

Adelaide Medical School

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.

Belinda completed her PhD in 2009 at the Heart Research Institute in Sydney. In 2011 she was awarded an NHMRC Early Career Training Fellowship to undertake research at the Centre for Vascular Research. Belinda joined SAHMRI mid-way through 2015 as a Senior Post Doctoral Fellow and her current research interests include the effect of lipids and lipid-lowering therapies on the process of vascular inflammation and calcification in heart disease and diabetes. She currently leads the Vascular Inflammation group in the Heart Health Theme at SAHMRI.

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  • Appointments
    Date Position Institution name
    2015 Afflliate University of Adelaide
    2015 Senior Post Doctoral Fellow South Australian Health and Medical Research Institute, Adelaide
    2014 - 2015 Affiliate University of Sydney, Sydney
    2014 - 2015 Senior Post Doctoral Researcher The Heart Research Institute
    2009 - 2014 Post Doctoral Researcher The University of New South Wales

  • Awards and Achievements
    Date Type Title Institution Name Country Amount
    2017 Award Tom Simpson Trust Fund Award Heart Foundation — —
    2017 Award Australian Atherosclerosis Society Trust Award — — —
    2015 Award ATVB Junior Investigator for Women Finalist — — —
    2014 Award ATVB Young Investigator Finalist American Heart Association — —
    2014 Award Best Post Doctoral Poster Presentation ISCP State of the Heart – Australian Vascular Biology Society — —
    2013 Award Best Poster Award European Atherosclerosis Society — —
    2012 Award Best Post Doctoral Poster Presentation Australian Vascular Biology Society — —
    2012 Fellowship Early Career Fellowship – Peter Doherty Award NHMRC — —
    2011 Award Post Doctoral Travel Award University of New South Wales — —
    2011 Award Young Investigator Award Asia-Pacific Society of Atherosclerosis and Vascular Diseases (APSAVD) Congress — —
    2011 Award Best Post Doctoral Oral presentation Australian Vascular Biology Society — —
    2010 Award BioAssayLINK Award Australian Atherosclerosis Society — —
    2010 Award Young Investigator Award Australian Atherosclerosis Society — —
    2010 Award Post Doctoral Travel Award University of New South Wales — —
    2009 Award Young Investigator Award XV International Symposium on Atherosclerosis — —
    2009 Award Student Travel Award National Heart Foundation, Australia — —
    2009 Award Student Travel Award Australian Atherosclerosis Society — —

  • Language Competencies
    Language Competency
    English Can read, write, speak, understand spoken and peer review

  • Education
    Date Institution name Country Title
    2006 - 2009 University of Sydney, Sydney Australia PhD
    — University of Sydney, Sydney Australia BMedSc

  • Research Interests
    Biochemistry & Molecular Biology Cardiovascular Medicine and Haematology Cell Biology
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  • Journals
    Year Citation
    2019 Toledo-Flores, D., Williamson, A., Schwarz, N., Fernando, S., Dimasi, C., Witt, T., . . . Psaltis, P. (2019). Vasculogenic properties of adventitial Sca-1 <sup>+</sup> CD45 <sup>+</sup> progenitor cells in mice: a potential source of vasa vasorum in atherosclerosis. Scientific Reports, 9(1), 15 pages.
    DOI
    2018 Cannizzo, C., Adonopulos, A., Solly, E., Ridiandries, A., Vanags, L., Mulangala, J., . . . Tan, J. (2018). VEGFR2 is activated by high-density lipoproteins and plays a key role in the proangiogenic action of HDL in ischemia. FASEB Journal, 32(6), 2911-2922.
    DOI Scopus1 WoS2
    2018 Takata, K., Di Bartolo, B., & Nicholls, S. (2018). High-Density Lipoprotein Infusions. Cardiology Clinics, 36(2), 311-315.
    DOI
    2018 Andrews, J., Psaltis, P., Bartolo, B., Nicholls, S., & Puri, R. (2018). Coronary arterial calcification: A review of mechanisms, promoters and imaging. Trends in Cardiovascular Medicine, 28(8), 491-501.
    DOI Scopus3 WoS3 Europe PMC1
    2018 Di Bartolo, B., & Straub, A. (2018). Highlights from vascular discovery: From genes to medicine scientific sessions 2018. Journal of the American Heart Association, 7(15), e009470.
    DOI
    2018 Di Bartolo, B., Psaltis, P., Bursill, C., & Nicholls, S. (2018). Translating evidence of HDL and plaque regression. Arteriosclerosis, thrombosis, and vascular biology, 38(9), 1961-1968.
    DOI
    2017 Di Bartolo, B., Schwarz, N., Andrews, J., & Nicholls, S. (2017). Infusional high-density lipoproteins therapies as a novel strategy for treating atherosclerosis. Archives of Medical Science, 13(1), 210-214.
    DOI Scopus2 WoS2 Europe PMC1
    2017 Di Bartolo, B., Scherer, D., Brown, A., Psaltis, P., & Nicholls, S. (2017). PCSK9 Inhibitors in Hyperlipidemia: Current Status and Clinical Outlook. BioDrugs, 31(3), 167-174.
    DOI Scopus4 WoS3 Europe PMC2
    2017 Cartland, S., Harith, H., Genner, S., Dang, L., Cogger, V., Vellozzi, M., . . . Kavurma, M. (2017). Non-alcoholic fatty liver disease, vascular inflammation and insulin resistance are exacerbated by TRAIL deletion in mice. Scientific Reports, 7(1), 1898.
    DOI Scopus13 Europe PMC6
    2017 Di Bartolo, B., & Nicholls, S. (2017). Anacetrapib as a potential cardioprotective strategy. Drug Design, Development and Therapy, 11, 3497-3502.
    DOI Scopus1 WoS1
    2016 Di Bartolo, B., Scherer, D., & Nicholls, S. (2016). Inducing apolipoprotein A-I synthesis to reduce cardiovascular risk: From ASSERT to SUSTAIN and beyond. Archives of Medical Science, 12(6), 1302-1307.
    DOI Scopus8 WoS8 Europe PMC6
    2016 Di Bartolo, B., Duong, M., & Nicholls, S. (2016). Clinical trials with cholesteryl ester transfer protein inhibitors. Current Opinion in Lipidology, 27(6), 545-549.
    DOI Scopus8 WoS8 Europe PMC5
    2016 Di Bartolo, B., Takata, K., Duong, M., & Nicholls, S. (2016). CETP Inhibition in CVD prevention: an actual appraisal. Current Cardiology Reports, 18(5), 43-1-43-6.
    DOI Scopus10 WoS10 Europe PMC7
    2016 Harith, H., Di Bartolo, B., Cartland, S., Genner, S., & Kavurma, M. (2016). Insulin promotes vascular smooth muscle cell proliferation and apoptosis via differential regulation of tumor necrosis factor-related apoptosis-inducing ligand. Journal of Diabetes, 8(4), 568-578.
    DOI Scopus3 Europe PMC2
    2015 Duong, M., Di Bartolo, B., & Nicholls, S. (2015). Acute high-density lipoprotein therapies. Current Opinion in Lipidology, 26(6), 521-525.
    DOI Scopus2 WoS2
    2015 Di Bartolo, B., Cartland, S., Prado-Lourenco, L., Griffith, T., Gentile, C., Ravindran, J., . . . Kavurma, M. (2015). Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) promotes angiogenesis and ischemia-induced neovascularization via NADPH oxidase 4 (NOX4) and nitric oxide-dependent mechanisms. Journal of the American Heart Association, 4(11), e002527.
    DOI Scopus20 Europe PMC10
    2014 Di Bartolo, B., & Kavurma, M. (2014). Regulation and function of Rankl in arterial calcification. Current Pharmaceutical Design, 20(37), 5853-5861.
    DOI Scopus4 Europe PMC1
    2013 Di Bartolo, B., Cartland, S., Harith, H., Bobryshev, Y., Schoppet, M., & Kavurma, M. (2013). TRAIL-Deficiency Accelerates Vascular Calcification in Atherosclerosis via Modulation of RANKL. PLoS ONE, 8(9), e74211.
    DOI Scopus35 Europe PMC19
    2012 Azahri, N., Di Bartolo, B., Khachigian, L., & Kavurma, M. (2012). Sp1, acetylated histone-3 and p300 regulate TRAIL transcription: Mechanisms of PDGF-BB-mediated VSMC proliferation and migration. Journal of Cellular Biochemistry, 113(8), 2597-2606.
    DOI Scopus22 Europe PMC16
    2011 Di Bartolo, B., Chan, J., Bennett, M., Cartland, S., Bao, S., Tuch, B., & Kavurma, M. (2011). TNF-related apoptosis-inducing ligand (TRAIL) protects against diabetes and atherosclerosis in Apoe -/- mice. Diabetologia, 54(12), 3157-3167.
    DOI Scopus71 Europe PMC58
    2011 Di Bartolo, B., Vanags, L., Tan, J., Bao, S., Rye, K., Barter, P., & Bursill, C. (2011). The apolipoprotein A-I mimetic peptide, ETC-642, reduces chronic vascular inflammation in the rabbit.. Lipids in health and disease, 10(1), 224.
    DOI Scopus17 WoS17 Europe PMC9
    2011 Di Bartolo, B., Nicholls, S., Bao, S., Rye, K., Heather, A., Barter, P., & Bursill, C. (2011). The apolipoprotein A-I mimetic peptide ETC-642 exhibits anti-inflammatory properties that are comparable to high density lipoproteins. Atherosclerosis, 217(2), 395-400.
    DOI Scopus32 WoS34 Europe PMC27
    2011 Di Bartolo, B., Schoppet, M., Mattar, M., Rachner, T., Shanahan, C., & Kavurma, M. (2011). Calcium and osteoprotegerin regulate IGF1R expression to inhibit vascular calcification. Cardiovascular Research, 91(3), 537-545.
    DOI Scopus26 Europe PMC16
    2010 Patel, S., Di Bartolo, B., Nakhla, S., Heather, A., Mitchell, T., Jessup, W., . . . Rye, K. (2010). Anti-inflammatory effects of apolipoprotein A-I in the rabbit. Atherosclerosis, 212(2), 392-397.
    DOI Scopus51 Europe PMC43
    2010 Chan, J., Prado-Lourenco, L., Khachigian, L., Bennett, M., Di Bartolo, B., & Kavurma, M. (2010). TRAIL promotes VSMC proliferation and neointima formation in a FGF-2-, Sp1 Phosphorylation-, and NFκB-Dependent Manner. Circulation Research, 106(6), 1061-1071.
    DOI Scopus55 Europe PMC38
    2009 Peshavariya, H., Dusting, G., Di Bartolo, B., Rye, K., Barter, P., & Jiang, F. (2009). Reconstituted high-density lipoprotein suppresses leukocyte NADPH oxidase activation by disrupting lipid rafts. Free Radical Research, 43(8), 772-782.
    DOI Scopus24 Europe PMC15
    2009 McGrath, K., Li, X., Puranik, R., Liong, E., Tan, J., Dy, V., . . . Heather, A. (2009). Role of 3β-hydroxysteroid-Δ24 reductase in mediating antiinflammatory effects of high-density lipoproteins in endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology, 29(6), 877-882.
    DOI Scopus61 Europe PMC42
    2006 Cutri, B., Hime, N., & Nicholls, S. (2006). High-density lipoproteins: An emerging target in the prevention of cardiovascular disease. Cell Research, 16(10), 799-808.
    DOI Scopus20 WoS20 Europe PMC12
    2006 Nicholls, S., Lundman, P., Harmer, J., Cutri, B., Griffiths, K., Rye, K., . . . Celermajer, D. (2006). Consumption of saturated fat impairs the anti-inflammatory properties of high-density lipoproteins and endothelial function. Journal of the American College of Cardiology, 48(4), 715-720.
    DOI Scopus144 WoS131 Europe PMC88
    2005 Nicholls, S., Cutri, B., Worthley, S., Kee, P., Rye, K., Bao, S., & Barter, P. (2005). Impact of short-term administration of high-density lipoproteins and atorvastatin on atherosclerosis in rabbits. Arteriosclerosis Thrombosis and Vascular Biology, 25(11), 2416-2421.
    DOI Scopus128 WoS121 Europe PMC88
    2005 Nicholls, S., Dusting, G., Cutri, B., Bao, S., Drummond, G., Rye, K., & Barter, P. (2005). Reconstituted high-density lipoproteins inhibit the acute pro-oxidant and proinflammatory vascular changes induced by a periarterial collar in normocholesterolemic rabbits. Circulation, 111(12), 1543-1550.
    DOI Scopus224 WoS208 Europe PMC164

  • Conference Papers
    Year Citation
    2008 Di Bartolo, B. A., Bao, S., Rye, K. -A., Nicholls, S. J., & Barter, P. J. (2008). In vivo properties of a novel apolipoprotein A-1 mimetic peptide. In JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol. 51 (pp. A283). Chicago, IL: ELSEVIER SCIENCE INC.

2016                National Heart Foundation Ahrens Grant for 2016 $65000

2014                University of Sydney Early Career Research Grant $25000 for 2015

2011                NHMRC Early Career Fellowship – Peter Doherty Award 2012-2017

2011                University of New South Wales  Post Doctoral Small Grant Program $10,000

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  • Current Higher Degree by Research Supervision (University of Adelaide)
    Date Role Research Topic Program Degree Type Student Load Student Name
    2017 Co-Supervisor Role of HDL in diabetes impaired angiogenesis and vascular calcification Doctor of Philosophy Doctorate Full Time Ms Jocelyne Mulangala
    2017 Co-Supervisor The role of HDL in vascular calcification and atherosclerosis Doctor of Philosophy Doctorate Full Time Miss Emma Jill Akers
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