Dr Beatriz Jimenez Garrido
Senior Lecturer
School of Physics, Chemistry and Earth Sciences
Faculty of Sciences, Engineering and Technology
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Journals
Year Citation 2025 Antcliffe, D. B., Harte, E., Hussain, H., Jiménez, B., Browning, C., & Gordon, A. C. (2025). Metabolic septic shock sub-phenotypes, stability over time and association with clinical outcome. Intensive Care Medicine, 51(3), 529-541.
2025 Yan, Y., Jiménez, B., Judge, M. T., Athersuch, T., De Iorio, M., & Ebbels, T. M. D. (2025). MetAssimulo 2.0: a web app for simulating realistic 1D and 2D metabolomic 1H NMR spectra. Bioinformatics, 41(3), btaf045.
2025 Xu, K., Hernández, B., Arpawong, T. E., Camuzeaux, S., Chekmeneva, E., Crimmins, E. M., . . . Robinson, O. (2025). Assessing Metabolic Ageing via DNA Methylation Surrogate Markers: A Multicohort Study in Britain, Ireland and the USA. Aging Cell, 24(5), e14484.
2024 Yan, Y., Judge, M. T., Athersuch, T., Xiang, Y., Liu, Z., Jiménez, B., & Ebbels, T. M. D. (2024). Resolution Enhancement of Metabolomic J-Res NMR Spectra Using Deep Learning. Analytical Chemistry, 96(29), 11707-11715.
Scopus5 Europe PMC22024 Trainor, N., Whitwell, H. J., Jiménez, B., Addison, K., Leonidou, E., DiMaggio, P. A., & Fuchter, M. J. (2024). Tracking DOT1L methyltransferase activity by stable isotope labelling using a selective synthetic co-factor. Communications Chemistry, 7(1), 145.
Scopus12023 Alexander, J. L., Wyatt, N. J., Camuzeaux, S., Chekmeneva, E., Jimenez, B., Sands, C. J., . . . Lamb, C. A. (2023). Considerations for peripheral blood transport and storage during large-scale multicentre metabolome research. Gut, 73(2), 379-383.
Scopus3 Europe PMC12023 Garcia‐Segura, M. E., Durainayagam, B. R., Liggi, S., Graça, G., Jimenez, B., Dehghan, A., . . . Griffin, J. L. (2023). Pathway‐based integration of multi‐omics data reveals lipidomics alterations validated in an Alzheimer's disease mouse model and risk loci carriers. Journal of Neurochemistry, 164(1), 57-76.
Scopus11 Europe PMC132023 Harvey, N., Takis, P. G., Lindon, J. C., Li, J. V., & Jiménez, B. (2023). Optimization of Diffusion-Ordered NMR Spectroscopy Experiments for High-Throughput Automation in Human Metabolic Phenotyping. Analytical Chemistry, 95(6), 3147-3152.
Scopus6 Europe PMC32022 Hussain, H., Vutipongsatorn, K., Jiménez, B., & Antcliffe, D. B. (2022). Patient Stratification in Sepsis: Using Metabolomics to Detect Clinical Phenotypes, Sub-Phenotypes and Therapeutic Response. Metabolites, 12(5), 42 pages.
Scopus25 Europe PMC242022 Sliz, E., Shin, J., Ahmad, S., Williams, D. M., Frenzel, S., Gauß, F., . . . Pausova, Z. (2022). Circulating Metabolome and White Matter Hyperintensities in Women and Men. Circulation, 145(14), 1040-1052.
Scopus22 Europe PMC222022 Albreht, A., Hussain, H., Jiménez, B., Yuen, A. H. Y., Whiley, L., Witt, M., . . . Chekmeneva, E. (2022). Structure Elucidation and Mitigation of Endogenous Interferences in LC-MS-Based Metabolic Profiling of Urine. Analytical Chemistry, 94(3), 1760-1768.
Scopus8 Europe PMC52021 Takis, P. G., Jiménez, B., Al-Saffar, N. M. S., Harvey, N., Chekmeneva, E., Misra, S., & Lewis, M. R. (2021). A Computationally Lightweight Algorithm for Deriving Reliable Metabolite Panel Measurements from 1D 1H NMR. Analytical Chemistry, 93(12), 4995-5000.
Scopus6 Europe PMC52021 Whiley, L., Chappell, K. E., D’Hondt, E., Lewis, M. R., Jiménez, B., Snowden, S. G., . . . Holmes, E. (2021). Metabolic phenotyping reveals a reduction in the bioavailability of serotonin and kynurenine pathway metabolites in both the urine and serum of individuals living with Alzheimer’s disease. Alzheimer S Research and Therapy, 13(1), 18 pages.
Scopus82 Europe PMC692021 Jiménez, B., Abellona U, M. R., Drymousis, P., Kyriakides, M., Clift, A. K., Liu, D. S. K., . . . Frilling, A. (2021). Neuroendocrine neoplasms: Identification of novel metabolic circuits of potential diagnostic utility. Cancers, 13(3), 1-17.
Scopus3 Europe PMC32020 Andreas, N. J., Basu Roy, R., Gomez-Romero, M., Horneffer-van der Sluis, V., Lewis, M. R., Camuzeaux, S. S. M., . . . Kampmann, B. (2020). Performance of metabonomic serum analysis for diagnostics in paediatric tuberculosis. Scientific Reports, 10(1), 11 pages.
Scopus10 Europe PMC92020 Kurbatova, N., Garg, M., Whiley, L., Chekmeneva, E., Jiménez, B., Gómez-Romero, M., . . . Lovestone, S. (2020). Urinary metabolic phenotyping for Alzheimer’s disease. Scientific Reports, 10(1), 17 pages.
Scopus31 Europe PMC272020 Takis, P. G., Jiménez, B., Sands, C. J., Chekmeneva, E., & Lewis, M. R. (2020). SMolESY: An efficient and quantitative alternative to on-instrument macromolecular 1H-NMR signal suppression. Chemical Science, 11(23), 6000-6011.
Scopus19 Europe PMC132019 Rodriguez-Martinez, A., Ayala, R., Posma, J. M., Harvey, N., Jiménez, B., Sonomura, K., . . . Dumas, M. E. (2019). PJRES Binning Algorithm (JBA): A new method to facilitate the recovery of metabolic information from pJRES 1H NMR spectra. Bioinformatics, 35(11), 1916-1922.
Scopus12 Europe PMC102019 Harbaum, L., Ghataorhe, P., Wharton, J., Jiménez, B., Howard, L. S. G., Gibbs, J. S. R., . . . Wilkins, M. R. (2019). Reduced plasma levels of small HDL particles transporting fibrinolytic proteins in pulmonary arterial hypertension. Thorax, 74(4), 380-389.
Scopus37 Europe PMC292019 Whiley, L., Chekmeneva, E., Berry, D. J., Jiménez, B., Yuen, A. H. Y., Salam, A., . . . Lewis, M. R. (2019). Systematic Isolation and Structure Elucidation of Urinary Metabolites Optimized for the Analytical-Scale Molecular Profiling Laboratory. Analytical Chemistry, 91(14), 8873-8882.
Scopus12 Europe PMC102019 Sands, C. J., Wolfer, A. M., Correia, G. D. S., Sadawi, N., Ahmed, A., Jiménez, B., . . . Pearce, J. T. M. (2019). The nPYc-Toolbox, a Python module for the pre-processing, quality-control and analysis of metabolic profiling datasets. Bioinformatics, 35(24), 5359-5360.
Scopus28 Europe PMC252018 Jiménez, B., Holmes, E., Heude, C., Tolson, R. F., Harvey, N., Lodge, S. L., . . . Nicholson, J. K. (2018). Quantitative Lipoprotein Subclass and Low Molecular Weight Metabolite Analysis in Human Serum and Plasma by 1H NMR Spectroscopy in a Multilaboratory Trial. Analytical Chemistry, 90(20), 11962-11971.
Scopus179 Europe PMC1592018 Gafson, A. R., Thorne, T., McKechnie, C. I. J., Jimenez, B., Nicholas, R., & Matthews, P. M. (2018). Lipoprotein markers associated with disability from multiple sclerosis. Scientific Reports, 8(1), 8 pages.
Scopus28 Europe PMC242017 Rodriguez-Martinez, A., Posma, J. M., Ayala, R., Harvey, N., Jimenez, B., Neves, A. L., . . . Dumas, M. E. (2017). J-Resolved 1H NMR 1D-Projections for Large-Scale Metabolic Phenotyping Studies: Application to Blood Plasma Analysis. Analytical Chemistry, 89(21), 11405-11412.
Scopus19 Europe PMC152017 Antcliffe, D., Jiménez, B., Veselkov, K., Holmes, E., & Gordon, A. C. (2017). Metabolic Profiling in Patients with Pneumonia on Intensive Care. Ebiomedicine, 18, 244-253.
Scopus21 Europe PMC152017 Ferrario, C., Statello, R., Carnevali, L., Mancabelli, L., Milani, C., Mangifesta, M., . . . Turroni, F. (2017). How to feed the Mammalian gut microbiota: Bacterial and metabolic modulation by dietary fibers. Frontiers in Microbiology, 8(SEP), 1749.
Scopus74 Europe PMC602017 Bray, R., Cacciatore, S., Jiménez, B., Cartwright, R., Digesu, A., Fernando, R., . . . Khullar, V. (2017). Urinary Metabolic Phenotyping of Women with Lower Urinary Tract Symptoms. Journal of Proteome Research, 16(11), 4208-4216.
Scopus12 Europe PMC102016 Scientific Abstracts (2016). Reproductive Sciences, 23(1_suppl), 51A-344A.
2015 Jiménez, B. (2015). NMR-based metabolic phenotyping for disease diagnosis and stratification. Emagres, 4(2), 269-276.
2015 Correia, G. D. S., Wooi Ng, K., Wijeyesekera, A., Gala-Peralta, S., Williams, R., Maccarthy-Morrogh, S., . . . Pathan, N. (2015). Metabolic profiling of children undergoing surgery for congenital heart disease. Critical Care Medicine, 43(7), 1467-1476.
Scopus43 Europe PMC352015 Powles, S. T. R., Hicks, L. C., Jiménez, B., Merrifield, C., Holmes, E., Williams, H. R. T., & Orchard, T. R. (2015). PTH-069 Effect of co-morbidities on urinary metabolic profiling in the characterisation of patients with inflammatory bowel disease. Gut, 64(Suppl 1), A436.2-A437.
2014 Mirnezami, R., Jiménez, B., Li, J. V., Kinross, J. M., Veselkov, K., Goldin, R. D., . . . Darzi, A. (2014). Rapid diagnosis and staging of colorectal cancer via high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy of intact tissue biopsies. Annals of Surgery, 259(6), 1138-1149.
Scopus70 Europe PMC512014 Dona, A. C., Jiménez, B., Schafer, H., Humpfer, E., Spraul, M., Lewis, M. R., . . . Nicholson, J. K. (2014). Precision high-throughput proton NMR spectroscopy of human urine, serum, and plasma for large-scale metabolic phenotyping. Analytical Chemistry, 86(19), 9887-9894.
Scopus417 Europe PMC3222013 Jiménez, B., Mirnezami, R., Kinross, J., Cloarec, O., Keun, H. C., Holmes, E., . . . Nicholson, J. K. (2013). 1H HR-MAS NMR spectroscopy of tumor-induced local metabolic "field-effects" enables colorectal cancer staging and prognostication. Journal of Proteome Research, 12(2), 959-968.
Scopus111 Europe PMC812013 Kinross, J. M., Drymousis, P., Jiménez, B., & Frilling, A. (2013). Metabonomic profiling: A novel approach in neuroendocrine neoplasias. Surgery United States, 154(6), 1185-1193.
Scopus27 Europe PMC212012 Wong, A., Jiménez, B., Li, X., Holmes, E., Nicholson, J. K., Lindon, J. C., & Sakellariou, D. (2012). Evaluation of high resolution magic-angle coil spinning NMR spectroscopy for metabolic profiling of nanoliter tissue biopsies. Analytical Chemistry, 84(8), 3843-3848.
Scopus40 Europe PMC202012 Gómez-Mingot, M., Alcaraz, L. A., MacIntyre, D. A., Jiménez, B., Pineda-Lucena, A., Montiel, V., . . . Iniesta, J. (2012). Development of a novel analytical approach combining the quantification of amino acids, organic acids and glucose using HPLC-UV-Vis and HPLC-MS with screening via NMR. Analytical Methods, 4(1), 284-290.
Scopus72012 Jiménez, B., Ugwu, F., Zhao, R., Ortí, L., Makhnevych, T., Pineda-Lucena, A., & Houry, W. A. (2012). Structure of minimal tetratricopeptide repeat domain protein Tah1 reveals mechanism of its interaction with Pih1 and Hsp90. Journal of Biological Chemistry, 287(8), 5698-5709.
Scopus43 Europe PMC412011 MacIntyre, D. A., Sanchís, D. M., Jiménez, B., Moreno, R., Stojkovic, M., & Pineda-Lucena, A. (2011). Characterisation of human embryonic stem cells conditioning media by 1H-nuclear magnetic resonance spectroscopy. Plos One, 6(2), 11 pages.
Scopus21 Europe PMC162010 Jiménez, B., Montoliu, C., MacIntyre, D. A., Serra, M. A., Wassel, A., Jover, M., . . . Felipo, V. (2010). Serum metabolic signature of minimal hepatic encephalopathy by 1H-nuclear magnetic resonance. Journal of Proteome Research, 9(10), 5180-5187.
Scopus58 Europe PMC432010 MacIntyre, D. A., Jiménez, B., Lewintre, E. J., Martín, C. R., Schäfer, H., Ballesteros, C. G., . . . Pineda-Lucena, A. (2010). Serum metabolome analysis by 1H-NMR reveals differences between chronic lymphocytic leukaemia molecular subgroups. Leukemia, 24(4), 788-797.
Scopus135 Europe PMC832008 Mori, M., Jiménez, B., Piccioli, M., Battistoni, A., & Sette, M. (2008). The solution structure of the monomeric copper, zinc superoxide dismutase from Salmonella enterica: Structural insights to understand the evolution toward the dimeric structure. Biochemistry, 47(49), 12954-12963.
Scopus17 Europe PMC112008 Bertini, I., Jiménez, B., Pierattelli, R., Wedd, A. G., & Xiao, Z. (2008). Protonless 13C direct detection NMR: Characterization of the 37 kDa trimeric protein CutA1. Proteins Structure Function and Genetics, 70(4), 1196-1205.
Scopus13 Europe PMC72007 Jiménez, B., Mori, M., Battistoni, A., Sette, M., & Piccioli, M. (2007). NMR assignment of reduced form of copper, zinc superoxide dismutase from Salmonella enterica. Biomolecular NMR Assignments, 1(1), 65-67.
Scopus3 Europe PMC12006 Balayssac, S., Jiménez, B., & Piccioli, M. (2006). 13C direct detected COCO-TOCSY: A tool for sequence specific assignment and structure determination in protonless NMR experiments. Journal of Magnetic Resonance, 182(2), 325-329.
Scopus7 Europe PMC62006 Balayssac, S., Jiménez, B., & Piccioli, M. (2006). Assignment strategy for fast relaxing signals: Complete aminoacid identification in thulium substituted calbindin D9K. Journal of Biomolecular NMR, 34(2), 63-73.
Scopus32 Europe PMC172005 Alcaraz, L. A., Jiménez, B., Moratal, J. M., & Donaire, A. (2005). An NMR view of the unfolding process of rusticyanin: Structural elements that maintain the architecture of a β-barrel metalloprotein. Protein Science, 14(7), 1710-1722.
Scopus11 Europe PMC92005 Bertini, I., Jiménez, B., & Piccioli, M. (2005). 13C Direct detected experiments: Optimization for paramagnetic signals. Journal of Magnetic Resonance, 174(1), 125-132.
Scopus42 Europe PMC212005 Bertini, I., Jiménez, B., Piccioli, M., & Poggi, L. (2005). Asymmetry in13C-13C COSY spectra provides information on ligand geometry in paramagnetic proteins. Journal of the American Chemical Society, 127(35), 12216-12217.
Scopus21 Europe PMC72003 Jiménez, B., Piccioli, M., Moratal, J. M., & Donaire, A. (2003). Backbone dynamics of rusticyanin: The high hydrophobicity and rigidity of this blue copper protein is responsible for its thermodynamic properties. Biochemistry, 42(35), 10396-10405.
Scopus26 Europe PMC172003 Jiménez, B., Poggi, L., & Piccioli, M. (2003). Monitoring the Early Steps of Unfolding of Dicalcium and Mono-Ce 3+-Substituted Forms of P43M Calbindin D9k. Biochemistry, 42(44), 13066-13073.
Scopus5 Europe PMC32002 Donaire, A., Jiménez, B., Fernández, C. O., Pierattelli, R., Niizeki, T., Moratal, J. M., . . . Vila, A. J. (2002). Metal-ligand interplay in blue copper proteins studied by 1H NMR spectroscopy: Cu(II)-pseudoazurin and Cu(II)-rusticyanin. Journal of the American Chemical Society, 124(46), 13698-13708.
Scopus56 Europe PMC312001 Donaire, A., Jiménez, B., Moratal, J. M., Hall, J. F., & Hasnain, S. S. (2001). Electronic characterization of the oxidized state of the blue copper protein rusticyanin by 1H NMR: Is the axial methionine the dominant influence for the high redox potential?. Biochemistry, 40(3), 837-846.
Scopus42 Europe PMC272001 Bertini, I., Donaire, A., Jiménez, B., Luchinat, C., Parigi, G., Piccioli, M., & Poggi, L. (2001). Paramagnetism-based versus classical constraints: An analysis of the solution structure of Ca Ln calbindin D9k. Journal of Biomolecular NMR, 21(2), 85-98.
Scopus100 Europe PMC59- doi:10.1021/bi034638
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Book Chapters
Year Citation 2017 Jiménez, B., & MacIntyre, D. (2017). NMR Metabolic Phenotyping in Clinical Studies. In Encyclopedia of Spectroscopy and Spectrometry (pp. 140-145). Elsevier.
DOI Scopus22004 Jiménez, B., Moratal, J. M., Piccioli, M., & Donaire, A. (2004). Mobility Studies in Proteins by 15N Nuclear Magnetic Resonance: Rusticyanin as an Example. In Principles and Practice (pp. 15-33). Springer Berlin Heidelberg.
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