Associate Professor Bastien Llamas
School of Biological Sciences
Faculty of Sciences, Engineering and Technology
Eligible to supervise Masters and PhD - email supervisor to discuss availability.
Assoc. Prof. Bastien Llamas is a former ARC Future Fellow and is affiliated with the Australian Centre for Ancient DNA (ACAD). He is also Head of Genome Biology and Evolutionary Medicine in the Indigenous Genomics team of the Telethon Kids Institute, Associate Deputy Director of the ARC Centre of Excellence for Australian Biodiversity and Heritage (CABAH), and Honorary Associate Professor at the National Centre for Indigenous Genomics (NCIG) at the Australian National University. He aims to integrate past and present Indigenous genetic diversity from populations around the world to understand how humans adapt to their environment.
- My Research
- Grants and Funding
- Professional Activities
Assoc. Prof. Bastien Llamas pursued graduate studies in the area of biomedical research where he concentrated on mapping genes with phenotypic effects in animal models, particularly those associated with disease. During this training he developed expertise in the areas of molecular genomics and bioinformatics, forged by years of training in four research institutes in France (CNRS, Pasteur Institute, INSERM) and Canada (Montreal Cardiac Research Institute, IRCM).
During his postdoctoral appointments in Australia, Assoc. Prof. Llamas has undertaken intensive training in bioinformatics and High Throughput Sequencing (HTS) techniques through a series of overseas workshops and research visits. He has implemented these methods at the University of Adelaide's Australian Centre for Ancient DNA (ACAD) to facilitate the transition from PCR-based to HTS-based ancient DNA analysis, and trained students and postdoctoral researchers in HTS data generation and processing. To further disseminate his expertise in HTS data analysis, he has co-organised local, national, and international bioinformatics workshops, including the annual ACAD International ECR Bioinformatics Workshop.
Assoc. Prof. Llamas now intends to merge cutting-edge methods and knowledge from biomedical research with archaeological and evolutionary questions and datasets, in truly multi-disciplinary projects at ACAD and at the Australian National University's Centre for Indigenous Genomics (NCIG), where he is a Visiting Fellow.
Assoc. Prof. Llamas investigates genetic and epigenetic mechanisms and host-microbiome interactions that facilitate human adaptation to diverse environmental and cultural stressors. He intends to combine a range of advanced new analytical methods (e.g., long-read sequencing, genome graphs) to integrate past and present Indigenous genetic diversity from populations around the world into a new human pangenome reference.
Assoc. Prof. Llamas' other projects at ACAD target several topics in evolutionary biology, population genomics and medical genomics, including:
- Genomic resources for Indigenous Australians.
- The genetic history of Indigenous Australia.
- The genetic consequences of colonisation on the immune system of indigenous societies, with a focus on the dramatic South American population collapse after European colonisers introduced new Old World diseases.
- The migration history of anatomically modern humans and the reconstruction of major peopling events across the globe.
Media Outreach and Science Popularisation
- SBS three-part series “DNA Nation” on ancient human migrations and evolution, and accompanying interview
- Radio Adelaide interviews on various topics in evolutionary biology
- Radio Canada interview on the impact of early farming and the Industrial Revolution on the oral health (in French)
- Some of the mainstream newspaper and online articles based on Dr Llamas' research publications can be found here. Dr Llamas' research has received a considerable amount of media attention, and he has performed many interviews in Australia (including SBS, ABC, The Australian, The Examiner), the USA (National Geographic, Science Magazine), Canada (including Radio Canada), New Zealand (including Radio New Zealand National), France (Le Monde), Spain (including Agencia Efe, El Pais, La Vanguardia), and Chile (El Mercurio)
- Contributions to the blog of the French Canadian Science Press Agency "Agence Science Presse". Some posts were published in the book "Science, on blogue!" © Éditions MultiMondes, 2007
- Collaborations with Adelaide Compass, a group that works with students from low socio-economic status, regional and indigenous communities, increasing student exposure to the university environment through relevant and engaging curriculum-linked programs
Interested in epigenetics research in South Australia? Join EpiCSA now!
Date Position Institution name 2022 - 2027 Honorary Associate Professor Australian National University 2022 - ongoing Head, Genome Biology and Evolutionary Medicine Telethon Kids Institute 2022 - ongoing Associate Professor University of Adelaide 2020 - 2022 Visiting Fellow Australian National University 2018 - 2021 ARC Future Fellow University of Adelaide 2017 - 2017 University Research Fellow University of Adelaide 2015 - 2016 Senior Research Associate University of Adelaide 2013 - 2015 Senior Research Associate University of Adelaide 2010 - 2013 ARC Australian Postdoctoral Fellow University of Adelaide 2009 - 2010 Research Associate Flinders University 2009 - 2009 Postdoctoral Researcher University of Adelaide 2008 - 2009 Postdoctoral Researcher University of Adelaide 2007 - 2008 Postdoctoral Researcher Institut de Recherche Clinique de Montréal (IRCM) 2003 - 2007 PhD candidate Institut de Recherche Clinique de Montréal (IRCM)
Language Competency English Can read, write, speak, understand spoken and peer review French Can read, write, speak, understand spoken and peer review Spanish; Castilian Can read, speak and understand spoken
Date Institution name Country Title 2003 - 2007 University of Montreal Canada PhD in Molecular Biology 2000 - 2001 Bordeaux Segalen University France MSc in Neurosciences 1997 - 1999 University of Paris-Sud France BSc in Genetics and Evolution 1994 - 1997 University of Marne la Vallée France Diploma of Higher Education
Year Citation 2018 Papac, L., Llamas, B., Cooper, A., Pilbrow, V., & Haak, W. (2018). Preliminary ancient DNA screening results from first to eighth century AD sites in Samtavro and Tchkantiskedi, Georgia. In A. Batmaz, G. Bedianashvili, A. Michalewicz, & A. Robinson (Eds.), Context and Connection: Studies on the Archaeology of the Ancient Near East in Honour of Antonio Sagona (Vol. 268, pp. 783-786). Leuven - Paris - Bristol, CT: Peeters Publishers. 2005 Llamas, B., & Deschepper, C. F. (2005). Identification and validation of Loci and candidate genes linked to cardiac hypertrophy.. In Molecular Cardiology (Vol. 112, pp. 321-337). Humana Press.
DOI Scopus1 Europe PMC1
Year Citation 2015 Mathieson, I., Haak, W., Patterson, N., Mallick, S., Llamas, B., Rohland, N., . . . Reich, D. (2015). Phenotypic inference from ancient DNA. In AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY Vol. 156 (pp. 217). St Louis, MO: WILEY-BLACKWELL. 2006 Lau, C., Llamas, B., Deschepper, C., & Cupples, W. A. (2006). Strain dependent differences in variance of heart rate and mean arterial pressure in normotensive rats. In FASEB JOURNAL Vol. 20 (pp. A313). San Francisco, CA: FEDERATION AMER SOC EXP BIOL. 2005 Llamas, B., & Deschepper, C. F. (2005). The chromosome Y contributes to features of dilated eccentric hypertrophy in male C57Bl/6J mice. In CIRCULATION RESEARCH Vol. 97 (pp. E12). Keystone, CO: LIPPINCOTT WILLIAMS & WILKINS.
Year Citation 2020 Llamas, B. (2020). Bisulphite sequencing of ancient genomes. Poster session presented at the meeting of AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY. Los Angeles, CA: WILEY. 2018 Fehren-Schmitz, L., Posth, C., Skoglund, P., Llamas, B., Haak, W., Krause, J., & Reich, D. (2018). Genome wide data from pre-Columbian South America. Poster session presented at the meeting of Abstracts of the 87th Annual Meeting of the American Association of Physical Anthropologists (AAPA 2018), as published in American Journal of Physical Anthropology. Austin, TX: Wiley.
2015 Fehren-Schmitz, L., Skoglund, P., Llamas, B., Lindauer, S., Tomasto, E., Kuzminsky, S., . . . Reich, D. (2015). Genome-wide data from ancient Peruvian highlanders and the Population History of South America. Poster session presented at the meeting of AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY. St Louis, MO: WILEY-BLACKWELL. 2015 Khong, J. J., Wang, L., Smyth, G., McNab, A., Hardy, T., Selva, D., . . . Craig, J. (2015). GENE EXPRESSION PROFILING OF ORBITAL ADIPOSE TISSUE IN THYROID ORBITOPATHY. Poster session presented at the meeting of CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY. WILEY-BLACKWELL. 2015 Miller, C., Franks, C., Breen, J., Weyrich, L., Soubrier, J., Llamas, B., . . . Cooper, A. (2015). Open access to ancient human DNA: An Australian Centre for Ancient DNA (ACAD) and University Libraries collaboration. Poster session presented at the meeting of Proceedings of eResearch Australasia 2016. Brisbane, Australia: eResearch Australasia. 2013 Fehren-Schmitz, L., Llamas, B., Haak, W., Tomasto-Cagiao, E., Coutinho, A., Williams, S. R., & Benfer, R. A. (2013). A palaeogenetic investigation into the pre-Columbian population history of Central Andean South America. Poster session presented at the meeting of AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY. Knoxville, TN: WILEY-BLACKWELL. 2012 Khong, J. J., McNab, A., Hardy, T., Davies, G., Selva, D., Ebeling, P., . . . Craig, J. (2012). GENE EXPRESSION PROFILING OF ORBITAL FAT TISSUE IN THYROID ORBITOPATHY IMPLICATING WNT SIGNALING AND T CELL RECEPTOR SIGNALLING PATHWAY IN THE PATHOGENESIS OF THYROID ORBITOPATHY. Poster session presented at the meeting of CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY. WILEY-BLACKWELL.
Grants and Funding
- 2023–2025: National Health and Medical Research Council Ideas 2021172: "Indigenous telomere-2-telomere human reference genomes to enable discovery, translation and innovations." Investigators: Hardip Patel, Azure Hermes, Karen Miga, Andre Luiz Martins Reis, Yu Lin, Paul Waters, Bastien Llamas. AUD 2,549,487
- 2022–2027: Medical Research Future Fund, 2021 Genomics Health Futures Mission Grant MRF2016124: "Pathways to benefit for Indigenous Australians in genomic medicine." Investigators: Alex Brown, Johanna Barclay, Gareth Baynam, Shayne Bellingham, James Breen, Ngiare Brown, Vanessa Bryant, Rebecca D'Souza, Marcel Dinger, Clara Gaff, Kalinda Griffiths, David Hansen, Karen Hawke, Azure Hermes, Sharon Huebner, Elina Hypponen, Jodie Ingles, David James, Misty Jenkins, Jason Kovacic, Timo Lassmann, Bastien Llamas, Raymond Lovett, David Lynn, Louise Lyons, Daniel MacArthur, Graham Mann, Julie McGaughran, Rebekah McWhirter, Sarah Medland, Kim Morey, Shivashankar Hiriyur Nagaraj, Kristen Nowak, Nathan O'Callaghan, Hardip Patel, Glenn Pearson, Odette Pearson, Gregory Pratt, Boe Rambaldini, Simone Reynolds, Stephen Simpson, Charlotte Slade, Yassine Souilmi, David Thomas, Maree Toombs, Mark Wenitong, Jean Yang. AUD 4,986,948
- 2022–2027: National Health and Medical Research Council Synergy 2011277: "Respecting the Gift - Empowering Indigenous Communities in Genomic Medicine." Investigators: Alex Brown, Azure Hermes, Gregory Pratt, Kalinda Griffiths, Graham Mann, Simon Easteal, Bastien Llamas, Gareth Baynam, Sharon Huebner, Daniel MacArthur. AUD 5,000,000
- 2022–2024: Medical Research Future Fund, 2021 Genomics Health Futures Mission Grant MRF2016008: "Developing a long-read nanopore sequencing platform for Indigenous genomics." Investigators: Ira Deveson, Gareth Baynam, Hasindu Gamaarachchi, Bastien Llamas, Daniel MacArthur, Amali Mallawaarachchi, Graham Mann, Andre Luiz Martins Reis, Hardip Patel, Yassine Souilmi. AUD 986,060
- 2022–2024: Australian Research Council Centre of Excellence CE170100015: "ARC Centre of Excellence for Australian Biodiversity and Heritage." Investigators: Richard Roberts, Susan O'Connor, Zenobia Jacobs, Timothy Cohen, Simon Haberle, Michael Bird, Sean Ulm, Nicholas Nakata, Corey Bradshaw, Bruno David, Lynette Russell, Barry Brook, Christopher Johnson, Brit Asmussen, Michael Slack, Jean-Jacques Delannoy, Matthew Leavesley, Michael Storey, Ian McNiven, Kristofer Helgen, Geraldine Mate, Vera Weisbecker, Janelle Stevenson, Nathan Wright, Shirley Agostinho, Shane Ingrey, Bastien Llamas, Elizabeth Muller. AUD 33,750,000 [Chief Investigator role from 1 Jan 2022, but grant was awarded in 2017]
- 2022–2023: Sandland Bequest: "Pandemic Preparedness: Viral Discovery and Characterisation in Adelaide's Botanic Park Grey-Headed Flying Fox Colony." Investigators: Kylie Van der Hoek, Michael Beard, Wayne Boardman, Anne-Lise Chaber, Bastien Llamas, Vilma Perez, Thomas Prowse, Charles Caraguel, Farhid Hemmatzadeh. AUD 55,600
- 2019-2021: Australian Research Council Discovery Project DP190103705: "Australian Heritage: Constructing the first Aboriginal reference genome." Investigators: Bastien Llamas, Brad Chapman, Erik Garrison, Lars Fehren-Schmitz. AUD435,000
- 2018-2021: Australian Research Council Future Fellowship FT170100448: "An integrated molecular approach to human evolution." Investigator: Bastien Llamas. AUD684,053
- 2016-2018: Australian Research Council Discovery Indigenous IN160100007: "The genomic history of Indigenous Australia." Investigators: Raymond Tobler, Bastien Llamas, Keryn Walshe, Peter Sutton, David Reich, Chris Tyler-Smith, Wolfgang Haak. AUD635,000
- 2015-2017: Hermon Slade Foundation: "Resolving the taxonomic status of ecologically keystone and threatened bats in New Guinea." Investigators: Kyle Armstrong, Ken Aplin, Bastien Llamas. AUD84,800
- 2013-16: Australian Research Council Linkage Project LP130100646: "The role of epigenetic modifications in bovid adaptation to environmental change." Investigators: Alan Cooper, Catherine M Suter, Mike J Wilkinson, Stefan G Hiendleder, Bastien Llamas, John R Stephen, Jeremy F Taylor, Daniel H Densham. AUD1,121,145 (ARC contribution AUD554,645)
- 2013-15: Australian Research Council Discovery Project DP130102158: "Refining the timescale of human evolution and dispersal using ancient DNA." Investigators: Wolfgang Haak, Simon Ho, Bastien Llamas, Doron Behar. AUD270,000 [Investigator role relinquished to become the project's Research Associate]
- 2010-12: Australian Research Council Discovery Project DP1095782: "A shipload of consequences: studying the impact of Old World diseases on native South American populations via ancient DNA." Investigators: Wolfgang Haak, Bastien Llamas, Lluis Quintana-Murci, Austin L. Hughes. AUD360,000
Awards, scholarships and fellowships
- The Genetics Society of AustralAsia Ross Crozier Medal — 2023
- University of Adelaide's Faculty of Sciences Mid-Career Research Excellence, Order of Merit — 2021.
- HLA Award of the European Federation for Immunogenetics annual conference — 2021.
- Australian Research Council Future Fellowship, 2018-2021
- Marie Skłodowska-Curie Individual Fellowship, 2017-2019 [relinquished to take up Future Fellowship]
- Vice Chancellor’s Research Fellowship of the University of Adelaide, 2017
- Overseas Conference Travel Award of the University of Adelaide Faculty of Sciences, 2015
- Travel award of the Centre for Research in Mathematics of the University of Montreal, October 2013
- Australian Research Council Postdoctoral Fellowship, 2010-2013
- Postdoctoral Fellowship (Quebec Fund for Research on Nature and Technologies), 2010-2012
- Overseas Conference Travel Award of the University of Adelaide Faculty of Sciences, 2011
- Writing scholarship of the Faculty of Graduate Studies of the University of Montreal, 2007
- Travel award of the Faculty of Graduate Studies of the University of Montreal, 2006
- Travel award of the International Mammalian Genome Conference, Strasbourg, France, 2005
- Educational award of the Canadian Hypertension Society, 2005
- André Caillé scholarship of the IRCM, 2005-2006
- Scholarship of the Faculty of Graduate Studies of the University of Montreal, 2004-2005
- Travel award of the Faculty of Graduate Studies of the University of Montreal, 2004
- AstraZeneca R&D presentation award, 10th Scientific Day of the Molecular Biology Programs of the University of Montreal, 2004
- Scholarship of the Faculty of Graduate Studies of the University of Montreal, 2003-2004
Teaching topics include ancient DNA, human population genomics and bioinformatics.
University of Adelaide:
ENV BIOL 3560 - Evolution of Australian Biota III
ENV BIOL 3535 - Research Methods in Evolutionary Biology III
BIOINF 3010 - Genomics Applications III
BIOTECH 7005 - Bioinformatics and Systems Modelling
BIOINF 7150 - Genomics Applications
Current Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2023 Co-Supervisor Using sedimentary DNA from caves to reconstruct past plant and animal communities in Australia Doctor of Philosophy Doctorate Full Time Miss Siobhan Esther Evans 2022 Principal Supervisor Applied Indigenous Genomics Doctor of Philosophy Doctorate Full Time Ms Dawn Alison Lewis 2022 Principal Supervisor Indigenous Genomics, Epigenetics & Applications to Disease Doctor of Philosophy Doctorate Full Time Samuel Arthur Luke Godwin 2022 Principal Supervisor New methods for integrating temporal environmental and genetic data Master of Philosophy Master Full Time Mr Shyamsundar Ravishankar 2022 Principal Supervisor Genetic Continuity and Population Dynamics in Eastern Indonesia Master of Philosophy Master Full Time Mr Leonard . 2021 Principal Supervisor This project will use ancient DNA to investigate the Inka empire. Firstly, I will aim to reconstruct the Inka rulers’ genetic origins. Secondly, I will investigate the impact of the Inka empire on the people it conquered in the Andean region. Doctor of Philosophy Doctorate Full Time Miss Roberta Lynn Davidson 2019 Co-Supervisor Exploring epigenetics in response to intergenerational trauma in Indigenous Australia: race, gender, and the production of scientific knowledge. Doctor of Philosophy Doctorate Full Time Miss Henrietta Rose Byrne
Past Higher Degree by Research Supervision (University of Adelaide)
Date Role Research Topic Program Degree Type Student Load Student Name 2021 - 2022 Principal Supervisor Advances in Genomic Data Compression Doctor of Philosophy Doctorate Full Time Mr Divon Mordechai Lan 2021 - 2022 Principal Supervisor Reconstructing the Population History of Wallacea and Sahul Doctor of Philosophy Doctorate Full Time Dr Gludhug Ariyo Purnomo 2020 - 2022 Principal Supervisor Post-contact evolutionary immunogenetics in Indigenous peoples of America Doctor of Philosophy Doctorate Full Time Ms Evelyn Jane Collen 2020 - 2022 Co-Supervisor Gut microbiome insights into the pathophysiology of inflammatory bowel disease Doctor of Philosophy Doctorate Full Time Miss Gina Lucille Guzzo 2019 - 2022 Principal Supervisor Human demographic insights from paleogenetic studies of American and Iberian skeletal remains Doctor of Philosophy Doctorate Full Time Mr Xavier Roca Rada 2019 - 2022 Principal Supervisor Quantifying and Reducing Biases in Paleogenomic Research Doctor of Philosophy Doctorate Full Time Mr Adrien Oliva 2017 - 2019 Co-Supervisor Inferring the Characteristics of Ancient Populations using Bioinformatic Analysis of Genome-wide DNA Sequencing Data Doctor of Philosophy Doctorate Full Time Mr Graham Gower 2017 - 2022 Principal Supervisor Exploring the Genetic History of the Ancient Near East through the Bronze
and Iron Ages
Doctor of Philosophy Doctorate Full Time Mr Matthew Peter Williams 2016 - 2019 Principal Supervisor The Role of Epigenetic Modifications and Microbiome Evolution in Bovid Adaption to Environmental Changes Doctor of Philosophy Doctorate Full Time Dr Yichen Liu 2015 - 2018 Co-Supervisor The 'next generation’ of ancient DNA research: a series of methods and approaches to improve our understanding of the evolutionary history of species in general, and European bison in particular Doctor of Philosophy Doctorate Full Time Miss Ayla Lore van Loenen 2013 - 2017 Co-Supervisor Climate-Driven Ecological Changes Through the Last Glacial Period: Innovations in Plant Ancient DNA and Stable Isotope Palaeoecology Doctor of Philosophy Doctorate Full Time Mr Tim Rabanus-Wallace 2011 - 2016 Co-Supervisor Ancient DNA from pre-Columbian South America Doctor of Philosophy Doctorate Full Time Mr Guido Marcelo Valverde Garnica
Date Role Board name Institution name Country 2020 - ongoing Board Member Adelaide University Soccer Club Board The University of Adelaide Australia
Date Role Committee Institution Country 2021 - ongoing Member GSA Committee Genetics Society of AustralAsia (GSA) Australia 2020 - ongoing Member GA4GH Equity, Diversity and Inclusion Advisory Group Global Alliance for Genomics and Health (GA4GH) United States 2019 - ongoing Secretary EpiCSA Organising Committee Epigenetics Consortium of South Australia (EpiCSA) Inc Australia 2019 - 2021 Representative AEpiA Management Committee Australian Epigenetics Alliance (AEpiA) Australia 2018 - 2022 Member SING Australia Organising Committee SING Australia (Summer Internship for Indigenous Peoples in Genomics) Australia 2018 - ongoing Member PoS Adelaide Organising Committee Pint of Science Australia 2017 - 2019 Chair Organising Committee Epigenetics Consortium of South Australia (EpiCSA) Inc Australia 2015 - 2017 Co-Chair Organising Committee Epigenetics Consortium of South Australia (EpiCSA) Inc Australia
Date Role Membership Country 2021 - ongoing Member Genetics Society of AustralAsia (GSA) Australia 2020 - ongoing Member Australian Bioinformatics and Computational Biology Society Inc Australia 2019 - ongoing Member American Association of Physical Anthropologists United States 2019 - ongoing Member Human Genome Organisation (HUGO) International Ltd. United States 2018 - ongoing Member Society for Molecular Biology and Evolution United States 2015 - ongoing Member The Epignetics Consortium of South Australia Incorporated (EpiCSA) Australia 2015 - ongoing Member Australian Epigenetics Alliance Australia 2013 - ongoing Member American Society for Human Genetics United States 2012 - ongoing Member Society for American Archaeology United States
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