Adjunct Associate Professor Antony Hooker

Antony Hooker
Team Leader - Radiation Health
School of Chemical Engineering
Faculty of Engineering, Computer and Mathematical Sciences

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Adjunct Associate Professor Antony Hooker

Appointments

Date Position Institution name
2011 Adjunct Associate Professor University of Adelaide
2002 Lecturer Flinders University

Awards and Achievements

Date Type Title Institution Name Amount
2016 Fellowship Fellow, Australasian Radiation Protection Society Australasian Radiation Protection Society nil

Education

Date Institution name Country Title
2002 Flinders University, Adelaide Australia PhD
1995 Flinders University, Adelaide Australia B.Biotech (Hons)

Research Interests

Cancer Cell Biology, Molecular Medicine, Radiation and Matter, Radiation Therapy, Radiology and Organ Imaging

Journals

Year Citation
2016 Li, K., Etschmann, B., Rae, N., Reith, F., Ryan, C., Kirkham, R. ... Brugger, J. (2016). Ore petrography using megapixel X-ray imaging: rapid insights into element distribution and mobilization in complex Pt and U-Ge-Cu ores. Economic Geology, 111, 2, 487-501.
10.2113/econgeo.111.2.487
2015 Li, K., Pring, A., Etschmann, B., Macmillan, E., Ngothai, Y., O'Neill, B. ... Brugger, J. (2015). Uranium scavenging during mineral replacement reactions. American Mineralogist, 100, 8-9, 1728-1735.
10.2138/am-2015-5125
2011 Hooker, A. (2011). Radiation and risk: Is it time for a regulatory threshold dose?. Australasian Physical and Engineering Sciences in Medicine, 34, 3, 299-301.
10.1007/s13246-011-0097-x
2009 Hooker, A., Grdina, D., Murley, J., Blyth, B., Ormsby, R., Bezak, E. ... Sykes, P. (2009). Low doses of amifostine protect from chromosomal inversions in spleen in vivo when administered after an occupationally relevant X-radiation dose. International Journal of Low Radiation, 6, 1, 43-56.
10.1504/IJLR.2009.026239
2007 Day, T., Hooker, A., Zeng, G. & Sykes, P. (2007). Low dose X-radiation adaptive response in spleen and prostate of Atm knockout heterozygous mice. International Journal of Radiation Biology, 83, 8, 523-534.
10.1080/09553000701420582
2007 Day, T., Zeng, G., Hooker, A., Bhat, M., Scott, B., Turner, D. & Sykes, P. (2007). Adaptive response for chromosomal inversions in pKZ1 mouse prostate induced by low doses of X radiation delivered after a high dose. Radiation Research, 167, 6, 682-692.
10.1667/RR0764.1
2007 Day, T. K., Zeng, G., Hooker, A. M., Bhat, M., Turner, D. R. & Sykes, P. J. (2007). Extremely low doses of X-radiation can induce adaptive responses in mouse prostate.. Dose-response : a publication of International Hormesis Society, 5, 4, 315-322.
10.2203/dose-response.07-019.day
2006 Zeng, G., Day, T., Hooker, A., Blyth, B., Bhat, M., Tilley, W. & Sykes, P. (2006). Non-linear chromosomal inversion response in prostate after low dose X-radiation exposure. Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 602, 1-2, 65-73.
10.1016/j.mrfmmm.2006.08.002
2006 Sykes, P., Morley, A. & Hooker, A. (2006). The PKZ1 Recombination Mutation Assay: A Sensitive Assay for Low Dose Studies. Dose-Response, 4, 2, dose-response.0-dose-response.0.
10.2203/dose-response.05-035.Sykes
2006 Day, T., Zeng, G., Hooker, A., Bhat, M., Scott, B., Turner, D. & Sykes, P. (2006). Extremely low priming doses of x radiation induce an adaptive response for chromosomal inversions in pKZ1 mouse prostate. Radiation Research, 166, 5, 757-766.
10.1667/RR0689.1
2006 Sykes, P., Day, T., Swinburne, S., Lane, J., Morley, A., Hooker, A. & Bhat, M. (2006). In vivo mutagenic effect of very low dose radiation. Dose-Reponse, 4, 4, 309-316.
10.2203/dose-response.06-004.Sykes
2004 Hooker, A., Morley, A., Tilley, W. & Sykes, P. (2004). Cancer-associated genes can affect somatic intrachromosomal recombination early in carcinogenesis. Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis, 550, 1-2, 1-10.
10.1016/j.mrfmmm.2004.01.003
2004 Hooker, A., Bhat, M., Day, T., Lane, J., Swinburne, S., Morley, A. & Sykes, P. (2004). The linear no-threshold model does not hold for low-dose ionizing radiation. Radiation Research, 162, 4, 447-452.
10.1667/RR3228
2002 hooker, A. M., Morley, A. A. & Sykes, P. J. (2002). Different doses of etoposide increase or decrease somatic intrachromosomal recombination in spleen of the pKZ1 mouse mutagenesis model. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 500, 117-124.
2002 Hooker, A., Home, R., Morley, A. & Sykes, P. (2002). Erratum: Dose-dependent increase or decrease of somatic intrachromosomal recombination produced by etoposide (Mutation Research (2002) 500 (117-124) PII: S0027510702000076). Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 505, 1-2, 95-.
10.1016/S0027-5107(02)00175-6
2002 Hooker, A., Home, R., Morley, A. & Sykes, P. (2002). Dose-dependent increase or decrease of somatic intrachromosomal recombination produced by etoposide. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 500, 1-2, 117-124.
10.1016/s0027-5107(02)00007-6
2001 Sykes, P., McCallum, B., Bangay, M., Hooker, A. & Morley, A. (2001). Effect of exposure to 900 MHz radiofrequency radiation on intrachromosomal recombination in pKZ1 mice. Radiation Research, 156, 5, 495-502.
10.1667/0033-7587(2001)156[0495:eoetmr]2.0.co;2
1999 Sykes, P., Hooker, A. & Morley, A. (1999). Inversion due to intrachromosomal recombination produced by carcinogens in a transgenic mouse model. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 427, 1, 1-9.
10.1016/S0027-5107(99)00084-6
1998 Sykes, P., Hooker, A., Harrington, C., Jacobs, A., Kingsbury, L. & Morley, A. (1998). Induction of somatic intrachromosomal recombination inversion events by cyclophosphamide in a transgenic mouse model. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 397, 2, 209-219.
10.1016/S0027-5107(97)00213-3
1997 Sykes, P. J., Hooker, A. M., Harrington, C. S., Jacobs, A. K., Kingsbury, L. & Morley, A. A. (1997). P XV.24 Induction of somatic intrachromosomal recombination inversion events by cyclophosphamide in a transgenic mouse model. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 379, 1, S152-S152.
10.1016/S0027-5107(97)83147-8

Conference Papers

Year Citation
2004 Sykes, P., Day, T., Swinburne, S., Lane, J., Bhat, M., Morley, A. & Hooker, A. (2004). In vivo mutagenic effect of VERY low dose radiation.

GRANTS RECEIVED (Total = $6,723,821)

2016     Dixon DL, Boreham D, Hooker A.M. Investigation of the Immunological Mechanisms of Ultra-Low and Low Dose Radiation. $536,000. Collaborative research program between the Northern Ontario School of medicine (Ontario, Canada), Bruce Power (Ontario, Canada) and Flinders University, South Australia.

2014     Grano, S.R., Pring, A.O., Hooker, A.M., Spooner, N.A., D.J., Ngothai, Y.M., Ashman, P.J., Ebendorff-Heidepriem, H., Brugger, J., Wilson, S.A., Hayes, P.C., Peng, Y., Vaughan, J.W., Jak, E., Ehrig, K.J., Simons, S.J. ARC Research Hub for the Australian Copper-Uranium. $5,053,234

2007     Hooker, A.M. and Sykes, P.J. The use of whole body low dose X-radiation to reduce tumorigenicity in a murine prostate model. Flinders University Seeding Grant. $21,012.

2007     Hooker, A.M. and Sykes, P.J. Protection from chromosomal inversions by chemical radioprotectors. Flinders Medical Centre Foundation. $11,000.

2007     Hooker, A.M. Cancer Council of SA Travel Grant. $2,750.

2006     Sykes, P.J. and Hooker, A.M. The measurement of genetic damage (DNA inversions) in response to radiation. Australian Institute for Nuclear Science and Engineering (AINSE). $41,000.

2006     Hooker, A.M. Cancer Council of SA Travel Grant. $2,750.

2005     Sykes, P.J. and Hooker, A.M. Effect of low dose-rate radiation on somatic intrachromosomal recombination. Australian Institute for Nuclear Science and Engineering (AINSE). $24,100.

2005     Sykes, P.J. and Hooker, A.M. Mechanism for non-linear mutation dose response to low dose and ultra-low doses of LET radiation. US Department of Energy. US$ 1,050,000.

2005     Hooker. A.M and Sykes, P.J. Treatment of pKZ1 mice with radioprotectors. Flinders Medical Centre Foundation. $10,000.

2005     Bryan, D-L. and Hooker, A.M. Breathing in chronic Heart failure: Is there novel pulmonary compensation? Flinders Institute for Health and Medical Research CRG. $3,000.

2003     Hooker, A.M. Australian Institute for Nuclear Science and Engineering (AINSE) Young Investigator Travel Award. $500 + return airfare to Brisbane.

2003     Hooker, A.M.  Cancer Council of SA Travel Grant. $2,000.

2001     Hooker, A.M.  Anti-Cancer Foundation of SA Travel Grant. $225.

1999     Sykes, P.J. and Hooker, A.M. The role of somatic intrachromosomal recombination in mutation and cancer in a transgenic mouse model.  Flinders University Research Budget. $2,250.

Memberships

Date Role Membership Country
2015 - ongoing Member Radiation Research Society United States
2011 - ongoing Member Australasian College of Physcial Scientists and Engineers in Medicine
2006 - ongoing Member Australasian Radiation Protection Society

Committee Memberships

Date Role Committee Institution Country
2015 - ongoing Member ANZCTC CBRNe Training Advisory Group Attorney Generals Department Australia
2013 - ongoing Member International Academic Advisors, Asian and Oceanic Radiation Protection Association
2013 - 2015 President Australasian Radiation Protection Society
2013 - ongoing Representative Asian and Oceanic Radiation Protection Association Australia
2009 - ongoing Advisory Board Member State (SA) CBRN Emergency Management Scientific and Training Committee
2009 - ongoing Advisory Board Member State (SA) CBRN Emergency Management Committee Australia
2006 - ongoing Member Australasian Radiation Protection Society Australia
Position
Team Leader - Radiation Health
Campus
North Terrace
Org Unit
School of Chemical Engineering

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