Anthony Pisaniello

Anthony Pisaniello

School of Medicine

College of Health

Dr Anthony D Pisaniello MBBS PhD FRACP FACC FCSANZ FSCAI, Clinical Senior Lecturer, is an academic interventional and structural cardiologist with research interests in omega-3 fatty acids, aortic valve stenosis, and atherosclerosis. After completing general medical and cardiology training at the Royal Adelaide Hospital, he completed a PhD at The University of Adelaide, a TAVI Clinical Fellowship at Manchester Royal Infirmary, UK, and an Interventional Cardiology Fellowship at The Johns Hopkins Hospital, USA. His PhD studies investigated the impact of omega-3 fatty acids on inflammatory mediators in the vessel wall that promote atherosclerosis. This included cell, animal, and human studies, all randomised controlled trials. This research has been presented at numerous local and international meetings, including as a Finalist for the American College of Cardiology Young Investigator Award. The beneficial effects of omega-3 fatty acids on the atherosclerosis and other heart diseases, and the mechanisms leading to this, are a focus of Dr Pisaniello's research. He has already demonstrated a reduction in vascular inflammation with eicosapentanoic acid (EPA) supplementation, but no effect of omega-3s on aortic valve calcification.

Dr Pisaniello's research is studying the effects of omega-3 fatty acids on heart diseases, in particular atherosclerosis and aortic valve calcification.

Date Position Institution name
2014 - ongoing Clinical Senior Lecturer University of Adelaide

Date Institution name Country Title
2021 Society for Cardiovascular Angiography and Interventions United States Fellow
2020 Cardiac Society of Australia and New Zealand Australia Fellow
2020 American College of Cardiology United States Fellow
2014 - 2019 University of Adelaide Australia PhD
2013 Royal Australasian College of Physicians Australia Fellow
2001 - 2006 University of Adelaide Australia MBBS

Year Citation
2022 Pisaniello, A. D., Alfaddagh, A., Tibuakuu, M., Whelton, S. P., Czarny, M. J., Blaha, M. J., . . . Post, W. S. (2022). Association Between Omega-3 Fatty Acid Levels and Aortic Valve Calcium (from the Multi-Ethnic Study of Atherosclerosis). American Journal of Cardiology, 184, 104-110.
DOI Scopus2 WoS2 Europe PMC1
2021 Montarello, N. J., Salehi, T., Bate, A. P., Pisaniello, A. D., Clayton, P. A., Teo, K. S. L., . . . Coates, P. T. (2021). Multimodality Tachycardia-Induced Stress Testing Predicts a Low-Risk Group for Early Cardiovascular Mortality After Renal Transplantation. Kidney International Reports, 6(1), 120-127.
DOI Scopus2 WoS1 Europe PMC1
2021 Pisaniello, A. D., Makki, H. B. E., Jahangeer, S., Daniels, M. J., Hasan, R., & Fraser, D. G. W. (2021). Low Rates of Permanent Pacing Are Observed Following Self-Expanding Transcatheter Aortic Valve Replacement Using an Annular Plane Projection for Deployment. Circulation Cardiovascular Interventions, 14(1), E009258.
DOI Scopus15 WoS14 Europe PMC13
2021 Pisaniello, A. D., Fraser, D. G. W., Colville, H., & Hasan, R. (2021). Transcatheter Aortic Valve Replacement via the Right Subclavian Artery Approach: A Case Series. Innovations Technology and Techniques in Cardiothoracic and Vascular Surgery, 16(2), 188-191.
DOI Scopus2 WoS2 Europe PMC2
2021 Pisaniello, A. D., Psaltis, P. J., King, P. M., Liu, G., Gibson, R. A., Tan, J. T. M., . . . Di Bartolo, B. A. (2021). Omega-3 fatty acids ameliorate vascular inflammation: a rationale for their atheroprotective effects. Atherosclerosis, 324, 27-37.
DOI Scopus38 WoS36 Europe PMC32
2020 Dowling, C., Firoozi, S., Panoulas, V., Dalby, M., Kashyap, M. N., Kabir, T., . . . Brecker, S. J. (2020). Initial experience of a self-expanding transcatheter aortic valve with an outer pericardial wrap: The United Kingdom and Ireland Implanters' registry. Catheterization and Cardiovascular Interventions, 95(7), 1340-1346.
DOI Scopus12 WoS10 Europe PMC8
2020 Motwani, M., Burley, O., Luckie, M., Cunnington, C., Pisaniello, A. D., Hasan, R., . . . Fraser, D. G. (2020). 3D-printing assisted closure of paravalvular leak. Journal of Cardiovascular Computed Tomography, 14(5), e66-e68.
DOI Scopus7 WoS7 Europe PMC5
2018 Nicholls, S., Andrews, J., Kastelein, J., Merkely, B., Nissen, S., Ray, K., . . . Butters, J. (2018). Effect of serial infusions of CER-001, a pre-β High-density lipoprotein mimetic, on coronary atherosclerosis in patients following acute coronary syndromes in the CER-001 atherosclerosis regression acute coronary syndrome trial: A randomized clinical trial. JAMA Cardiology, 3(9), 815-822.
DOI Scopus162 WoS152 Europe PMC122
2018 Shishikura, D., Kataoka, Y., Pisaniello, A., Delacroix, S., Montarello, J., Nicholls, S., & Worthley, S. (2018). The extent of aortic atherosclerosis predicts the occurrence, severity, and recovery of acute kidney injury after transcatheter aortic valve replacement: A volumetric multislice computed tomography analysis. Circulation: Cardiovascular Interventions, 11(8), 11 pages.
DOI Scopus23 WoS20 Europe PMC14
2017 Andrews, J., Janssan, A., Nguyen, T., Pisaniello, A. D., Scherer, D. J., Kastelein, J. J. P., . . . Nicholls, S. J. (2017). Effect of serial infusions of reconstituted high-density lipoprotein (CER-001) on coronary atherosclerosis: Rationale and design of the CARAT study. Cardiovascular Diagnosis and Therapy, 7(1), 45-51.
DOI Scopus48 WoS45 Europe PMC33
2016 Kataoka, Y., Puri, R., Pisaniello, A., Hammadah, M., Qintar, M., Uno, K., . . . Worthley, S. (2016). Aortic atheroma burden predicts acute cerebrovascular events after transcatheter aortic valve implantation: insights from volumetric multislice computed tomography analysis. EuroIntervention, 12(6), 783-789.
DOI Scopus21 WoS18 Europe PMC15
2015 Pisaniello, A. D., Scherer, D. J., Kataoka, Y., & Nicholls, S. J. (2015). Ongoing challenges for pharmacotherapy for dyslipidemia. Expert Opinion on Pharmacotherapy, 16(3), 347-356.
DOI Scopus6 WoS6 Europe PMC6
2015 Dundon, B. K., Pisaniello, A. D., Nelson, A. J., Maia, M., Teo, K. S. L., Worthley, S. G., . . . Worthley, M. I. (2015). Dobutamine Stress Cardiac MRI for Assessment of Coronary Artery Disease Prior to Kidney Transplantation. American Journal of Kidney Diseases, 65(5), 808-809.
DOI Scopus9 WoS7 Europe PMC7
2014 Nicholls, S., Pisaniello, A., Kataoka, Y., & Puri, R. (2014). Lipid pharmacotherapy for treatment of atherosclerosis. Expert Opinion on Pharmacotherapy, 15(8), 1119-1125.
DOI Scopus13 WoS13 Europe PMC12
2013 Pisaniello, A., Wong, D., Kajani, I., Robinson, K., & Shakib, S. (2013). Anaemia in chronic heart failure: more awareness is required. Internal Medicine Journal, 43(9), 999-1004.
DOI Scopus14 WoS9 Europe PMC8

Year Citation
2019 Pisaniello, A. D., King, P., Di Bartolo, B. A., Liu, G., Gibson, R. A., Tan, J. T. M., . . . Nicholls, S. (2019). IMPACT OF FISH OIL SUPPLEMENTATION ON ACUTE VASCULAR INFLAMMATION IN HEALTHY VOLUNTEERS. In JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY Vol. 73 (pp. 2091). New Orleans, LA: ELSEVIER SCIENCE INC.
DOI

Year Citation
2020 Pisaniello, A. D., Di Bartolo, B. A., Liu, G., King, P. M., Gibson, R. A., Tan, J. T. M., & Nicholls, S. J. (2020). EICOSAPENTAENOIC ACID AMELIORATES VASCULAR INFLAMMATION: A MECHANISTIC RATIONALE FOR ITS ATHEROPROTECTIVE EFFECTS. Poster session presented at the meeting of JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. Chicago, IL: ELSEVIER SCIENCE INC.
2014 Pisaniello, A., Dundon, B., Maia, M., Teo, K., Worthley, S., Bannister, K., . . . Worthley, M. (2014). DOBUTAMINE STRESS CARDIAC MRI RELIABLY PREDICTS SIGNIFICANT CORONARY DISEASE IN RENAL TRANSPLANT CANDIDATES. Poster session presented at the meeting of INTERNAL MEDICINE JOURNAL. WILEY-BLACKWELL.

Dr Pisaniello's research has been supported by the National Health and Medical Research Council (NHMRC), the Cardiac Society of Australia and New Zealand, and the University of Adelaide.

Dr Pisaniello has both clinical and research teaching responsibilities, predominantly at the postgraduate level.

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