Anna Brown

Anna Brown

Centre for Cancer Biology

College of Health


Dr Anna BrownHead of Molecular Oncology at SA PathologySA Pathology University of South Australia.2017 - SA Pathology, Head Molecular Oncology.Affiliate Senior Lecturer, School of Paediatrics and Reproductive Health, University of Adelaide, Adelaide, 2007 - presentCentre for Cancer Biology, Adjunct Senior Research Fellow. University of South Australia.

Research Interests and Areas of Expertise
  • Molecular Oncology, including the application of Next Generation Sequencing techniques, with special expertise in application to haematological malignancies
  • Models of normal and malignant haematopoiesis
  • Scientific writing - preparation of manuscripts and grant applications
  • Science communication – professional and for a lay audience

For more information please visit: http://www.centreforcancerbiology.org.au/research/laboratories/molecular-pathology-research-laboratory/

Date Position Institution name
2017 - ongoing Head of Molecular Oncology SA Pathology
2015 - 2017 Senior Research Fellow University of South Australia & SA Pathology
2008 - 2015 Senior Post-Doctoral Research Officer SA Pathology
2007 - ongoing Affiliate Senior Lecturer University of Adelaide, Adelaide

Date Institution name Country Title
1999 University of Queensland, Brisbane Australia PhD
1994 University of Adelaide, Adelaide Australia Bachelor of Science (Honours)

Year Citation
2025 Shah, M. V., Hung, K., Baranwal, A., Kutyna, M. M., Al-Kali, A., Toop, C., . . . Hiwase, D. K. (2025). Evidence-based risk stratification of myeloid neoplasms harboring TP53 mutations. Blood Advances, 9(13), 3370-3380.
DOI Scopus6 WoS3 Europe PMC5
2025 Sharplin, K. M., Vassiliou, C., Nguyen, J., Kuss, B. J., Ting, S. B., Mangos, H., . . . Ross, D. M. (2025). Response to venetoclax in patients with blastic plasmacytoid dendritic cell neoplasm. Leukemia Research, 152, 7 pages.
DOI
2025 Wiseman, T., Spooner, M., Khanna, S., Hung, K., Toop, C., Kutyna, M. M., . . . Hiwase, D. K. (2025). RBC Transfusion Dependency Refines the Molecular International Prognostic Scoring System for Myelodysplastic Syndrome. Blood Advances, 9(16), 4244-4247.
DOI Scopus2 Europe PMC2
2025 Shah, M. V., Hung, K., Baranwal, A., Wechalekar, G., Al-Kali, A., Toop, C. R., . . . Hiwase, D. (2025). Validation of the 5th edition of the World Health Organization and International Consensus Classification guidelines for TP53-mutated myeloid neoplasm in an independent international cohort. Blood Cancer Journal, 15(1), 88-1-88-11.
DOI Scopus2 WoS2 Europe PMC1
2025 Kok, C. H., Al-Kali, A., Thomas, D., He, R., Kutyna, M. M., Alkhateeb, H. B., . . . Hiwase, D. K. (2025). RAS Mutation Identifies a Poor Prognostic Molecular Subtype of Therapy-Related Myeloid Neoplasm. Blood Advances, 9(15), 3814-3818.
DOI
2024 Venugopal, P., Arts, P., Fox, L. C., Simons, A., Hiwase, D. K., Bardy, P. G., . . . Scott, H. S. (2024). Unravelling Facets of MECOM-Associated Syndrome: Somatic Genetic Rescue, Clonal Hematopoiesis and Phenotype Expansion. Blood Advances, 8(13), 3437-3443.
DOI Scopus4 WoS1 Europe PMC2
2024 Zerella, J. R., Homan, C. C., Arts, P., Lin, X., Spinelli, S. J., Venugopal, P., . . . Hahn, C. N. (2024). Germline ERG haploinsufficiency defines a new syndrome with cytopenia and hematological malignancy predisposition. Blood, 144(17), 1765-1780.
DOI Scopus8 WoS7 Europe PMC6
2024 Wechalekar, M. D., Zhao, L. -P., Kutyna, M. M., Hong, L. E., Li, J., Hung, K., . . . Hiwase, D. K. (2024). Myeloid neoplasms arising after methotrexate therapy for autoimmune rheumatological diseases do not exhibit poor-risk molecular features. Blood Cancer Journal, 14(1), 116-1-116-5.
DOI Scopus1 WoS1 Europe PMC1
2024 Lim, K., Kan, W. L., Nair, P. C., Kutyna, M., Lopez, A. F., Hercus, T., . . . Thomas, D. (2024). CBL mutations in chronic myelomonocytic leukemia often occur in the RING domain with multiple subclones per patient: Implications for targeting. PLoS One, 19(9), e0310641-1-e0310641-19.
DOI Scopus1 Europe PMC1
2024 Lim, J., Ross, D. M., Brown, A. L., Scott, H. S., & Hahn, C. N. (2024). Germline genetic variants that predispose to myeloproliferative neoplasms and hereditary myeloproliferative phenotypes. Leukemia Research, 146, 10 pages.
DOI Scopus2 WoS2 Europe PMC2
2024 Hong, L. E., Wechalekar, M. D., Kutyna, M. M., Small, A., Lim, K., Thompson-Peach, C. A., . . . Hiwase, D. K. (2024). IDH-Mutant Myeloid Neoplasms are Associated with Seronegative Rheumatoid Arthritis and Innate Immune Activation. Blood, 143(18), 1873-1877.
DOI Scopus11 WoS11 Europe PMC10
2023 Samaraweera, S. E., Geukens, T., Casolari, D. A., Nguyen, T., Sun, C., Bailey, S., . . . Ross, D. M. (2023). Novel modes of MPL activation in triple-negative myeloproliferative neoplasms. Pathology, 55(1), 77-85.
DOI Scopus2 WoS2 Europe PMC2
2023 Saygin, C., Roloff, G. W., Hahn, C. N., Chhetri, R., Gill, S. I., Elmariah, H., . . . Godley, L. A. (2023). Allogeneic hematopoietic stem cell transplant outcomes in adults with inherited myeloid malignancies. Blood Advances, 7(4), 549-554.
DOI Scopus41 WoS42 Europe PMC36
2023 Hiwase, D. K., Hahn, C. N., Tran, E. N. H., Chhetri, R., Baranwal, A., Al-Kali, A., . . . Shah, M. V. (2023). TP53 mutation in therapy-related myeloid neoplasm defines a distinct molecular subtype. Blood, 141(9), 1087-1091.
DOI Scopus30 WoS25 Europe PMC26
2023 Homan, C. C., Scott, H. S., & Brown, A. L. (2023). Hereditary platelet disorders associated with germline variants in RUNX1, ETV6 and ANKRD26. Blood, 141(13), 1533-1543.
DOI Scopus39 WoS40 Europe PMC35
2023 Flerlage, J. E., Myers, J. R., Maciaszek, J. L., Oak, N., Rashkin, S. R., Hui, Y., . . . Rampersaud, E. (2023). Discovery of novel predisposing coding and noncoding variants in familial Hodgkin lymphoma. Blood, 141(11), 1293-1307.
DOI Scopus15 WoS13 Europe PMC14
2023 Shah, M. V., Tran, E. N. H., Shah, S., Chhetri, R., Baranwal, A., Ladon, D., . . . Hiwase, D. K. (2023). TP53 mutation variant allele frequency of ≥10% is associated with poor prognosis in therapy-related myeloid neoplasms. Blood Cancer Journal, 13(1), 51-1-51-9.
DOI Scopus32 WoS32 Europe PMC29
2023 Zerella, J. R., Homan, C. C., Arts, P., Brown, A. L., Scott, H. S., & Hahn, C. N. (2023). Transcription factor genetics and biology in predisposition to bone marrow failure and hematological malignancy. Frontiers in Oncology, 13, 1-33.
DOI Scopus3 WoS3 Europe PMC4
2023 Homan, C. C., Drazer, M. W., Yu, K., Lawrence, D. M., Feng, J., Arriola-Martinez, L. A., . . . Brown, A. L. (2023). Somatic mutational landscape of hereditary hematopoietic malignancies caused by germ line RUNX1, GATA2, and DDX41 variants. Blood Advances, 7(20), 6092-6107.
DOI Scopus29 WoS26 Europe PMC22
2022 Feurstein, S., Luo, X., Shah, M., Walker, T., Mehta, N., Wu, D., & Godley, L. A. (2022). Revision of RUNX1 variant curation rules. Blood Advances, 6(16), 4726-4730.
DOI Scopus13 WoS11 Europe PMC10
2022 Duncavage, E. J., Bagg, A., Hasserjian, R. P., DiNardo, C. D., Godley, L. A., Iacobucci, I., . . . Cazzola, M. (2022). Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia. Blood, 140(21), 2228-2247.
DOI Scopus163 WoS154 Europe PMC137
2022 Shah, M., Hahn, C. N., Tran, E. N. H., Sharplin, K. M., Chhetri, R., Baranwal, A., . . . Hiwase, D. (2022). <i>TP53</i> Mutation Status Defines a Distinct Clinicopathological Entity of Therapy-Related Myeloid Neoplasm, Characterized By Genomic Instability and Extremely Poor Outcome. BLOOD, 140(Supplement 1), 9798-9799.
DOI WoS2
2022 Tawana, K., Brown, A. L., & Churpek, J. E. (2022). Integrating germline variant assessment into routine clinical practice for myelodysplastic syndrome and acute myeloid leukaemia: current strategies and challenges. British Journal of Haematology, 196(6), 1293-1310.
DOI Scopus40 WoS37 Europe PMC36
2022 Brown, A. L. (2022). And the germline beat (AML) goes on. Blood, 139(8), 1126-1128.
DOI
2022 Lewis, A. C., Pope, V. S., Tea, M. N., Li, M., Nwosu, G. O., Nguyen, T. M., . . . Pitson, S. M. (2022). Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia.. Blood, 139(26), 3737-3751.
DOI Scopus37 WoS32 Europe PMC35
2022 Drazer, M. W., Homan, C. C., Yu, K., Cavalcante de Andrade Silva, M., McNeely, K. E., Pozsgai, M. J., . . . Godley, L. A. (2022). Clonal hematopoiesis in patients with ANKRD26 or ETV6 germline mutations.. Blood Adv, 6(15), 4357-4359.
DOI Scopus21 WoS21 Europe PMC16
2022 Bassal, M. A., Samaraweera, S. E., Lim, K., Bernard, B. A., Bailey, S., Kaur, S., . . . D'Andrea, R. J. (2022). Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia. Nature Communications, 13(1), 1-12.
DOI Scopus18 WoS19 Europe PMC16
2022 Bassal, M. A., Samaraweera, S. E., Lim, K., Benard, B. A., Bailey, S., Kaur, S., . . . D'Andrea, R. J. (2022). Author Correction: Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia.. Nat Commun, 13(1), 4131.
DOI Scopus2 WoS2 Europe PMC1
2021 Homan, C. C., Venugopal, P., Arts, P., Shahrin, N. H., Feurstein, S., Rawlings, L., . . . Hahn, C. N. (2021). GATA2 deficiency syndrome: a decade of discovery. Human Mutation, 42(11), 1399-1421.
DOI Scopus51 WoS43 Europe PMC41
2021 Six, K. A., Gerdemann, U., Brown, A. L., Place, A. E., Cantor, A. B., Kutny, M. A., & Avagyan, S. (2021). B-cell acute lymphoblastic leukemia in patients with germline RUNX1 mutations. Blood Advances, 5(16), 3199-3202.
DOI Scopus12 WoS12 Europe PMC12
2021 Avagyan, S., & Brown, A. L. (2021). To T or not to B: Germline RUNX1 mutation preferences in pediatric ALL predisposition. Journal of Clinical Investigation, 131(17), 4 pages.
DOI Scopus5 WoS5 Europe PMC5
2021 Samaraweera, S. E., Wang, P. P. S., Li, K. L., Casolari, D. A., Feng, J., Pinese, M., . . . D'Andrea, R. J. (2021). Childhood acute myeloid leukemia shows a high level of germline predisposition. Blood, 138(22), 2293-2298.
DOI Scopus11 WoS9 Europe PMC9
2021 Corboy, G., Othman, J., Lee, L., Wei, A., Ivey, A., Blombery, P., . . . Stevenson, W. (2021). Laboratory quality assessment of candidate gene panel testing for acute myeloid leukaemia: a joint ALLG / RCPAQAP initiative. Pathology, 53(4), 487-492.
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2021 Singhal, D., Hahn, C. N., Feurstein, S., Wee, L. Y. A., Moma, L., Kutyna, M. M., . . . Hiwase, D. K. (2021). Targeted gene panels identify a high frequency of pathogenic germline variants in patients diagnosed with a hematological malignancy and at least one other independent cancer. Leukemia, 35(11), 3245-3256.
DOI Scopus48 WoS46 Europe PMC44
2021 Homan, C. C., King-Smith, S. L., Lawrence, D. M., Arts, P., Feng, J., Andrews, J., . . . Brown, A. L. (2021). The RUNX1 Database (RUNX1db): establishment of an expert curated RUNX1 registry and genomics database as a public resource for familial platelet disorder with myeloid malignancy.. Haematologica, 106(11), 3004-3007.
DOI Scopus42 WoS37 Europe PMC32
2021 Homan, C. C., Venugopal, P., Arts, P., Shahrin, N. H., Feurstein, S., Rawlings, L., . . . Hahn, C. N. (2021). Cover, Volume 42, Issue 11. Human Mutation, 42(11).
DOI
2020 Brown, A. L., Arts, P., Carmichael, C. L., Babic, M., Dobbins, J., Chong, C. -E., . . . Scott, H. S. (2020). RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML. Blood Advances, 4(6), 1131-1144.
DOI Scopus129 WoS117 Europe PMC106
2020 Brown, A. L., Hahn, C. N., & Scott, H. S. (2020). Secondary leukemia in patients with germline transcription factor mutations (RUNX1, GATA2, CEBPA). Blood, 136(1), 24-35.
DOI Scopus80 WoS73 Europe PMC78
2020 Fox, L. C., Tan, M., Brown, A. L., Arts, P., Thompson, E., Ryland, G. L., . . . Blombery, P. (2020). A synonymous GATA2 variant underlying familial myeloid malignancy with striking intrafamilial phenotypic variability. British Journal of Haematology, 190(5), e297-e301.
DOI Scopus14 WoS13 Europe PMC11
2020 Brown, A. L., & Hiwase, D. K. (2020). What's germane in the germline? Finding clinically relevant germline variants in myeloid neoplasms from tumor only screening. Leukemia Research, 96, 3 pages.
DOI Scopus4 WoS4 Europe PMC3
2020 Brown, A. L., Hahn, C., Hiwase, D., Godley, L. A., & Scott, H. S. (2020). Correct application of variant classification guidelines in germline RUNX1 mutated disorders to assist clinical diagnosis. LEUKEMIA & LYMPHOMA, 61(1), 2 pages.
DOI Scopus2 WoS2 Europe PMC2
2020 Venugopal, P., Gagliardi, L., Forsyth, C., Feng, J., Phillips, K., Babic, M., . . . Scott, H. S. (2020). Two monogenic disorders masquerading as one: severe congenital neutropenia with monocytosis and non-syndromic sensorineural hearing loss. BMC Medical Genetics, 21(1), 35-1-35-5.
DOI Scopus3 WoS3 Europe PMC3
2019 Cheah, J. J. C., Brown, A. L., Schreiber, A. W., Feng, J., Babic, M., Moore, S., . . . Scott, H. S. (2019). A novel germline SAMD9L mutation in a family with ataxia-pancytopenia syndrome and pediatric acute lymphoblastic leukemia. Haematologica, 104(7), e318-e321.
DOI Scopus17 WoS15 Europe PMC16
2019 Iacobucci, I., Wen, J., Meggendorfer, M., Choi, J. K., Shi, L., Pounds, S. B., . . . Mullighan, C. G. (2019). Genomic subtyping and therapeutic targeting of acute erythroleukemia. Nature genetics, 51(4), 694-704.
DOI Scopus122 WoS122 Europe PMC112
2019 Singhal, D., Wee, L. Y. A., Kutyna, M. M., Chhetri, R., Geoghegan, J., Schreiber, A. W., . . . Hiwase, D. K. (2019). The mutational burden of therapy-related myeloid neoplasms is similar to primary myelodysplastic syndrome but has a distinctive distribution. Leukemia, 33(12), 2842-2853.
DOI Scopus50 WoS48 Europe PMC44
2019 Luo, X., Feurstein, S., Mohan, S., Porter, C. C., Jackson, S. A., Keel, S., . . . Godley, L. A. (2019). ClinGen Myeloid Malignancy Variant Curation Expert Panel recommendations for germline RUNX1 variants. Blood Advances, 3(20), 2962-2979.
DOI Scopus122 WoS117 Europe PMC108
2018 Beck, D., Thoms, J., Palu, C., Herold, T., Shah, A., Olivier, J., . . . Pimanda, J. (2018). A four-gene lincRNA expression signature predicts risk in multiple cohorts of acute myeloid leukemia patients. Leukemia, 32(2), 263-272.
DOI Scopus38 WoS37 Europe PMC27
2018 Chong, C. -E., Venugopal, P., Stokes, P., Lee, Y., Brautigan, P., Yeung, D., . . . Scott, H. (2018). Differential effects on gene transcription and hematopoietic differentiation correlate with GATA2 mutant disease phenotypes. Leukemia, 32(1), 194-202.
DOI Scopus56 WoS54 Europe PMC52
2018 Maung, K. Z. Y., Leo, P. J., Bassal, M., Casolari, D. A., Gray, J. X., Bray, S. C., . . . Gonda, T. J. (2018). Rare variants in Fanconi anemia genes are enriched in acute myeloid leukemia. Blood Cancer Journal, 8(6), 50-1-50-5.
DOI Scopus16 WoS16 Europe PMC13
2018 Branford, S., Wang, P., Yeung, D. T., Thomson, D., Purins, A., Wadham, C., . . . Hughes, T. P. (2018). Integrative genomic analysis reveals cancer-associated mutations at diagnosis of CML in patients with high-risk disease. Blood, 132(9), 948-961.
DOI Scopus168 WoS157 Europe PMC140
2017 Cheah, J., Hahn, C., Hiwase, D., Scott, H., & Brown, A. (2017). Myeloid neoplasms with germline DDX41 mutation. International Journal of Hematology, 106(2), 163-174.
DOI Scopus80 WoS73 Europe PMC70
2017 Maciejewski, J. P., Padgett, R. A., Brown, A. L., & Müller-Tidow, C. (2017). DDX41-related myeloid neoplasia. Seminars in Hematology, 54(2), 94-97.
DOI Scopus45 WoS44 Europe PMC40
2017 Brown, A. L., Churpek, J. E., Malcovati, L., Döhner, H., & Godley, L. A. (2017). Recognition of familial myeloid neoplasia in adults. Seminars in Hematology, 54(2), 60-68.
DOI Scopus36 WoS33 Europe PMC29
2017 Gill, D., Del Greco M, F., Rawson, T. M., Sivakumaran, P., Brown, A., Sheehan, N. A., & Minelli, C. (2017). Age at Menarche and Time Spent in Education: A Mendelian Randomization Study. Behavior Genetics, 47(5), 480-485.
DOI Scopus20 Europe PMC17
2016 Lewinsohn, M., Brown, A. L., Weinel, L. M., Phung, C., Rafidi, G., Lee, M. K., . . . Scott, H. S. (2016). Novel germ line DDX41 mutations define families with a lower age of MDS/AML onset and lymphoid malignancies. Blood, 127(8), 1017-1023.
DOI Scopus189 WoS186 Europe PMC157
2016 Lynch, J. R., Yi, H., Casolari, D. A., Voli, F., Gonzales-Aloy, E., Fung, T. K., . . . Wang, J. Y. (2016). Gaq signaling is required for the maintenance of MLL-AF9-induced acute myeloid leukemia. Leukemia, 30(8), 1745-1748.
DOI Scopus8 WoS7 Europe PMC7
2016 Shahrin, N., Diakiw, S., Dent, L., Brown, A., & D'Andrea, R. (2016). Conditional knockout mice demonstrate function of Klf5 as a myeloid transcription factor. Blood, 128(1), 55-59.
DOI Scopus28 WoS29 Europe PMC28
2016 Li, S., Garrett-Bakelman, F. E., Chung, S. S., Sanders, M. A., Hricik, T., Rapaport, F., . . . Mason, C. E. (2016). Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia. Nature Medicine, 22(7), 792-799.
DOI Scopus314 WoS303 Europe PMC301
2015 Hahn, C., Ross, D., Feng, J., Beligaswatte, A., Hiwase, D., Parker, W., . . . Scott, H. (2015). A tale of two siblings: two cases of AML arising from a single pre-leukemic DNMT3A mutant clone. Leukemia, 29(10), 2101-2104.
DOI Scopus29 WoS26 Europe PMC28
2015 Forristal, C. E., Brown, A. L., Helwani, F. M., Winkler, I. G., Nowlan, B., Barbier, V., . . . Levesque, J. P. (2015). Hypoxia inducible factor (HIF)-2α accelerates disease progression in mouse models of leukemia and lymphoma but is not a poor prognosis factor in human AML. Leukemia, 29(10), 2075-2085.
DOI Scopus34 WoS34 Europe PMC37
2014 Perugini, M., Samaraweera, S. E., Brown, A. L., Cummings, N., Danner, S., Tiong, I. S., . . . D'Andrea, R. J. (2014). The Significance of GADD45A Promoter DNA Hypermethylation in AML: Association with IDH1/2 and TET2 Mutation. BLOOD, 124(21), 3 pages.
2014 Li, S., Garrett-Bakelman, F., Perl, A., Luger, S., Zhang, C., To, B., . . . Mason, C. (2014). Dynamic evolution of clonal epialleles revealed by methclone. Genome Biology, 15(9), 472-1-472-12.
DOI Scopus56 WoS76 Europe PMC59
2013 Li, S., Garrett-Bakelman, F., Akalin, A., Zumbo, P., Levine, R., To, L., . . . Mason, C. (2013). An optimized algorithm for detecting and annotating regional differential methylation. BMC Bioinformatics, 14(supp 5), 1-9.
DOI Scopus99 WoS95 Europe PMC82
2013 Diakiw, S., D'Andrea, R., & Brown, A. (2013). The double life of KLF5: Opposing roles in regulation of gene-expression, cellular function, and transformation. IUBMB Life, 65(12), 999-1011.
DOI Scopus51 WoS47 Europe PMC44
2013 Perugini, M., Iarossi, D., Kok, C., Cummings, N., Diakiw, S., Brown, A., . . . D'Andrea, R. (2013). GADD45A methylation predicts poor overall survival in acute myeloid leukemia and is associated with IDH1/2 and DNMT3A mutations. Leukemia, 27(7), 1588-1592.
DOI Scopus22 WoS21 Europe PMC21
2013 Diakiw, S., Perugini, M., Kok, C., Engler, G., Cummings, N., To, L., . . . D'Andrea, R. (2013). Methylation of KLF5 contributes to reduced expression in acute myeloid leukaemia and is associated with poor overall survival. British Journal of Haematology, 161(6), 884-888.
DOI Scopus17 WoS16 Europe PMC13
2013 Kok, C., Brown, A., Perugini, M., Iarossi, D., Lewis, I., & D'Andrea, R. (2013). The preferential occurrence of FLT3-TKD mutations in inv(16) AML and impact on survival outcome: A combined analysis of 1053 core-binding factor AML patients. British Journal of Haematology, 160(4), 557-559.
DOI Scopus9 WoS11 Europe PMC9
2012 Diakiw, S., Kok, C., To, L., Lewis, I., Brown, A., & D'Andrea, R. (2012). The granulocyte-associated transcription factor Krüppel-like factor 5 is silenced by hypermethylation in acute myeloid leukemia. Leukemia Research, 36(1), 110-116.
DOI Scopus22 WoS21 Europe PMC21
2012 Brown, A., Salerno, D., Sadras, T., Engler, G., Kok, C., Wilkinson, C., . . . D'Andrea, R. (2012). The GM-CSF receptor utilizes β-catenin and Tcf4 to specify macrophage lineage differentiation. Differentiation, 83(1), 47-59.
DOI Scopus23 WoS21 Europe PMC20
2012 White, D. L., Brown, A. L., D'Andrea, R. J., & Rice, A. M. (2012). Unraveling the "known unknowns": lessons and reflections from the new directions in leukemia research 2012 conference. Cancer Research, 72(17), 4300-4303.
DOI
2011 Hahn, C., Chong, C., Carmichael, C., Wilkins, E., Brautigan, P., Li, X., . . . Scott, H. (2011). Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia. Nature Genetics, 43(10), 1012-1019.
DOI Scopus543 WoS481 Europe PMC438
2010 Kok, C., Brown, A., Ekert, P., & D'Andrea, R. (2010). Gene expression analysis reveals HOX gene upregulation in trisomy 8 AML. Leukemia, 24(6), 1239-1243.
DOI Scopus13 WoS12 Europe PMC11
2010 Perugini, M., Brown, A., Salerno, D., Booker, G., Stojkoski, C., Hercus, T., . . . D'Andrea, R. (2010). Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common β-subunit. Blood, 115(16), 3346-3353.
DOI Scopus59 WoS52 Europe PMC45
2009 Powell, J., Thomas, D., Barry, E., Kok, C., McClure, B., Tsykin, A., . . . Guthridge, M. (2009). Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML. Blood, 114(23), 4859-4870.
DOI Scopus53 WoS51 Europe PMC49
2009 Perugini, M., Kok, C., Brown, A., Wilkinson, C., Salerno, D., Young, S., . . . D'Andrea, R. (2009). Repression of Gadd45α by activated FLT3 and GM-CSF receptor mutants contributes to growth, survival and blocked differentiation. Leukemia, 23(4), 729-738.
DOI Scopus20 WoS19 Europe PMC21
2009 Eppley, S. M., O'Quinn, R., & Brown, A. L. (2009). New sequence-tagged site molecular markers for identification of sex in Distichlis spicata. Molecular Ecology Resources, 9(5), 1373-1374.
DOI Scopus6
2006 Brown, A., Wilkinson, C., Waterman, S., Kok, C., Salerno, D., Diakiw, S., . . . D'Andrea, R. (2006). Genetic regulators of myelopoiesis and leukemic signaling identified by gene profiling and linear modeling. Journal of Leukocyte Biology, 80(2), 433-447.
DOI Scopus39 WoS36 Europe PMC39
2005 Phan, V. T., Shultz, D. B., Truong, B. T. H., Blake, T. J., Brown, A. L., Gonda, T. J., . . . Kogan, S. C. (2005). Erratum: Cooperation of cytokine signaling with chimeric transcription factors in leukemogenesis: PML-retinoic acid receptor alpha blocks growth factor-mediated differentiation (Molecular and Cellular Biology (2003) 23, 13 (4573-4585)). Molecular and Cellular Biology, 25(13), 5787.
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2004 Brown, A., Peters, M., D'Andrea, R., & Gonda, T. (2004). Constitutive mutants of the GM-CSF receptor reveal multiple pathways leading to myeloid cell survival, proliferation, and granulocyte-macrophage differentiation. Blood, 103(2), 507-516.
DOI Scopus14 WoS16 Europe PMC11
2003 Phan, V., Shultz, D., Truong, B., Blake, T., Brown, A., Gonda, T., . . . Kogan, S. (2003). Cooperation of cytokine signaling with chimeric transcription factors in leukemogenesis: PML-retinoic acid receptor alpha blocks growth factor-mediated differentiation. Molecular and Cellular Biology, 23(13), 4573-4585.
DOI Scopus12 WoS10 Europe PMC10
2001 Browes, C., Rowe, J., Brown, A., & Montano, X. (2001). Analysis of trk A and p53 association. FEBS Letters, 497(1), 20-25.
DOI Scopus9 Europe PMC7
2000 Lemercier, C., Brown, A., Mamani, M., Ripoche, J., & Reiffers, J. (2000). The rat Mist1 gene: Structure and promoter characterization. Gene, 242(1-2), 209-218.
DOI Scopus7 Europe PMC6
2000 Brown, A., Browes, C., Mitchell, M., & Montano, X. (2000). c-abl is involved in the association of p53 and trk A. Oncogene, 19(26), 3032-3040.
DOI Scopus20 Europe PMC16
1999 Brown, A. L., & Kay, G. F. (1999). Corrigendum: Bex1, a gene with increased expression in parthenogenetic embryos, is a member of a novel gene family on the mouse X chromosome (Human Molecular Genetics (1999) 8 (611-619)). Human Molecular Genetics, 8(5), 943.
Scopus1
1999 Brown, A. L., & Kay, G. F. (1999). Bex1, a gene with increased expression in parthenogenetic embryos, is a member of a novel gene family on the mouse X chromosome. Human Molecular Genetics, 8(4), 611-619.
DOI Scopus56 WoS56 Europe PMC53
1997 Sharrocks, A. D., Brown, A. L., Ling, Y., & Yates, P. R. (1997). The ETS-domain transcription factor family. International Journal of Biochemistry and Cell Biology, 29(12), 1371-1387.
DOI Scopus292 Europe PMC234

Year Citation
2023 Scott, H. S., Zerella, J., Homan, C., Arts, P., Lin, S., Spinelli, S. J., . . . Hahn, C. N. (2023). ERG Is a New Predisposition Gene for Bone Marrow Failure and Hematological Malignancy. In BLOOD Vol. 144 (pp. LBA8). CA, San Diego: ELSEVIER.
DOI WoS2
2023 Hong, L. E., Kok, C. H., Kutyna, M., Li, J. J., Chhetri, R., Ross, D. M., . . . Hiwase, D. (2023). High Prevalence of IDH Mutation in Myeloid Neoplasm with Concomitant Autoimmune Rheumatic Disorders. In BLOOD Vol. 142 (pp. 4 pages). CA, San Diego: ELSEVIER.
DOI
2023 Hiwase, D., Baranwal, A., Shah, S., Kutyna, M., Hahn, C. N., Abdelmajid, M., . . . Shah, M. V. (2023). Single-Hit TP53 mut Is Associated with Poor Outcomes in Therapy-Related but Not De Novo Myelodysplastic Syndromes: Importance of Clinical History. In BLOOD Vol. 142 (pp. 4 pages). CA, San Diego: ELSEVIER.
DOI
2023 Shah, M. V., Kutyna, M., Shah, S., Tran, E. N. H., Baranwal, A., Ladon, D., . . . Hiwase, D. (2023). Comparison of World Health Organization and International Consensus Classification Guidelines for Myeloid Neoplasms Harboring TP53-Mutations Using an Independent International Cohort. In BLOOD Vol. 142 (pp. 4 pages). CA, San Diego: ELSEVIER.
DOI WoS4
2022 Saygin, C., Roloff, G. W., Hahn, C. N., Chhetri, R., Gill, S., Elmariah, H., . . . Godley, L. A. (2022). Allogeneic Hematopoietic Stem Cell Transplant Outcomes in Adults with Inherited Myeloid Malignancies. In BLOOD Vol. 140 (pp. 10542-10544). LA, New Orleans: ELSEVIER.
DOI
2022 Brown, A. L., Homan, C., Drazer, M. W., Yu, K., Lawrence, D., Feng, J., . . . Godley, L. A. (2022). Somatic Mutational Landscape of Hereditary Hematopoietic Malignancies Associated with Germline Variants in <i>RUNX1</i>, <i>GATA2</i> and <i>DDX41</i>. In BLOOD Vol. 140 (pp. 4030-4033). LA, New Orleans: AMER SOC HEMATOLOGY.
DOI WoS5
2017 Branford, S., Wang, P., Yeung, D., Purins, A., Marum, J. E., Nataren, N., . . . Hughes, T. P. (2017). Integrative Genomics Reveals Cancer Associated Mutations Are Common at Diagnosis of CML in Patients with Poor Response to TKI Therapy. In BLOOD Vol. 130 (pp. 4 pages). Atlanta, GA: AMER SOC HEMATOLOGY.
2016 Bassal, M. A., Leo, P., Samaraweera, S. E., Maung, K. Z. Y., Babic, M., Venugopal, P., . . . D'Andrea, R. (2016). Metabolic Profiling of Adult Acute Myeloid Leukemia (AML). In BLOOD Vol. 128 (pp. 6 pages). San Diego, CA: AMER SOC HEMATOLOGY.
DOI WoS1
2016 Brown, A. L., Hahn, C. N., Carmichael, C., Wilkins, E., Babic, M., Chong, C. -E., . . . Scott, H. S. (2016). Expanded Phenotypic and Genetic Heterogeneity in the Clinical Spectrum of FPD-AML: Lymphoid Malignancies and Skin Disorders Are Common Features in Carriers of Germline <i>RUNX1</i> Mutations. In BLOOD Vol. 128 (pp. 6 pages). San Diego, CA: AMER SOC HEMATOLOGY.
DOI WoS2
2016 Maung, K. Z. Y., Leo, P., Brown, A. L., Bassal, M. A., Casolari, D. A., Ewing, A., . . . D'Andrea, R. (2016). Rare Variants Affecting the Fanconi Anaemia DNA Repair Genes Associate with Increased Risk for AML. In BLOOD Vol. 128 (pp. 5 pages). San Diego, CA: AMER SOC HEMATOLOGY.
DOI
2015 Hahn, C. N., Babic, M., Schreiber, A. W., Kutyna, M. M., Wee, L. A., Brown, A. L., . . . Hiwase, D. (2015). Rare and Common Germline Variants Contribute to Occurrence of Myelodysplastic Syndrome. In BLOOD Vol. 126 (pp. 4 pages). Orlando, FL: AMER SOC HEMATOLOGY.
DOI WoS3
2015 Garrett-Bakelman, F. E., Li, S., Chung, S. S., Hricik, T., Franck, R., Patel, J., . . . Melnick, A. (2015). Divergent Dynamics of Epigenetic and Genetic Heterogeneity in Relapsed Acute Myeloid Leukemia. In BLOOD Vol. 126 (pp. 3 pages). Orlando, FL: AMER SOC HEMATOLOGY.
DOI WoS2
2014 Brown, A. L., Sadras, T., Engler, G. A., Tunningley, R., Kofler, J., Leo, P. J., . . . D'Andrea, R. J. (2014). An ENU Mutagenesis Screen of FLT3-ITD Knock-in Mice Identifies Novel Gene Mutations That Lead to an Exacerbated Myeloproliferative Neoplasm. In BLOOD Vol. 124 (pp. 3 pages). San Francisco, CA: AMER SOC HEMATOLOGY.
2011 Brown, A. L., Tunningley, R., Engler, G. A., Gilliland, D. G., Lewis, I. D., Gonda, T., & D'Andrea, R. J. (2011). An ENU Mutagenesis Screen to Identify Genes Involved in the Induction of FLT3-ITD Positive Acute Myeloid Leukemia. In BLOOD Vol. 118 (pp. 611). San Diego, CA: AMER SOC HEMATOLOGY.
2010 Brown, A. L., Salerno, D. G., Wilkinson, C., Sadras, T., Kok, C., Perugini, M., . . . D'Andrea, R. J. (2010). THE GM-CSF RECEPTOR UTILIZES BETA-CATENIN AND TCF4 TO SPECIFY MACROPHAGE LINEAGE DIFFERENTIATION. In EXPERIMENTAL HEMATOLOGY Vol. 38 (pp. S46). Melbourne, AUSTRALIA: ELSEVIER SCIENCE INC.
2010 Perugini, M., Brown, A. L., Diakiw, S., Kok, C., Danner, S., Lewis, I. D., & D'Andrea, R. J. (2010). REPRESSION OF GADD45A BY DNA METHYLATION IN ACUTE MYELOID LEUKEMIA (AML). In EXPERIMENTAL HEMATOLOGY Vol. 38 (pp. S54-S55). Melbourne, AUSTRALIA: ELSEVIER SCIENCE INC.
2005 Wilkinson, C., Brown, A., Kok, C., Solomon, P., Goodall, G., Gonda, T., & D'Andrea, M. (2005). Expression profiling of a myeloid cell line model to identify novel transcription factors influencing myeloid cell differentiation proliferation and leukaemia. In Proceedings of 5th Australian Microarray Conference 2005 (pp. unknown). Australia: Unknown.

Year Citation
2018 Singhal, D., Wee, A., Kutyna, M. M., Babic, M., Chhetri, R., Parker, W., . . . Hiwase, D. K. (2018). Therapy-Related Myeloid Neoplasms (T-MN) and Primary MDS (PMDS) Patients with Very Low (VL) or Low (L) IPSS-R Score Share Clinical and Biological Characteristics and Have Similar Outcome. Poster session presented at the meeting of BLOOD. CA, San Diego: AMER SOC HEMATOLOGY.
DOI
2014 Maung, K. Z., Gray, J. X., Leo, P. J., Bassal, M., Brown, A. L., Bray, S. C., . . . Gonda, T. J. (2014). Whole Exome Sequencing of Acute Myeloid Leukaemia Patients Identifies Somatic and Germline Mutations in Fanconi Anaemia Genes. Poster session presented at the meeting of BLOOD. San Francisco, CA: AMER SOC HEMATOLOGY.
2012 Brown, A. L., Diakiw, S. M., Perugini, M., Cummings, N., Wei, A. H., To, L. B., . . . D'Andrea, R. J. (2012). A Regulatory Promoter Polymorphism and Hypermethylation of Intron 1 Are Associated with Reduced Expression of <i>KLF5</i> and Inferior Survival in AML. Poster session presented at the meeting of BLOOD. Atlanta, GA: AMER SOC HEMATOLOGY.
DOI
2012 Shahrin, N. H., Brown, A. L., Diakiw, S., & D'Andrea, R. J. (2012). Investigation of KLF5 Function in Normal Hematopoiesis.. Poster session presented at the meeting of BLOOD. Atlanta, GA: AMER SOC HEMATOLOGY.
DOI
2012 D'Andrea, R. J., Perugini, M., Diakiw, S. M., Kok, C. H., Salerno, D., Cummings, N., . . . Lewis, I. D. (2012). Methylation of the Proximal Promoter of <i>GADD45A</i> Is Common in Acute Myeloid Leukemia and Is Associated with Poor Survival. Poster session presented at the meeting of BLOOD. Atlanta, GA: AMER SOC HEMATOLOGY.
DOI
 
 
 

Date Role Research Topic Program Degree Type Student Load Student Name
2010 - 2015 Co-Supervisor Investigation of KLF5 function in normal haemopoiesis Doctor of Philosophy Doctorate Full Time Miss Hezrin Hezrin Shahrin
2006 - 2010 Co-Supervisor Identification and Functional Analysis of Gene Expression Changes in Acute Myeloid Leukaemia Doctor of Philosophy Doctorate Full Time APrf Chung Hoow Kok
2006 - 2011 External Supervisor Characterisation of the Role of KLF5 in Normal Haemopoiesis and Acute Myeloid Leukaemia Doctor of Philosophy Doctorate Full Time Ms Sonya Diakiw

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