Ankit Dutta

Ankit Dutta

Higher Degree by Research Candidate

Adelaide Medical School

Faculty of Health and Medical Sciences

I graduated from The University of Adelaide with a Bachelor of Science (Molecular Biology) with a double major in Biochemistry and Genetics in 2012.

Following graduation, I pursued an Honours degree with research focused on bone marrow mesenchymal stem cells and their role in osteoporosis; and received a First Class in Bachelor of Health Sciences (Physiology).

I have now undertaken my PhD studies in the field of cancer genomics, with a focus on the incurable blood cancer, Multiple Myeloma. I am a PhD candidate in the Myeloma Research Laboratory under the supervision of Prof. Andrew Zannettino and Dr. Duncan Hewett.

Additionally, I have an interest in Biotechnology participating in networking events and the Brandon Capital Partners life sciences venture capital internship program.

My research focus is on a genomic approach towards an understanding of clonal evolution and disease progression in multiple myeloma.

In almost every case, the largely incurable blood cancer multiple myeloma (MM), develops from asymptomatic disease stages known as monoclonal gammopathy of undetermined clinical significance (MGUS) and smouldering multiple myeloma (SMM). It is believed complex nonlinear genetic changes drive MGUS/SMM to develop into MM. To date, the genetic factors driving the progression from MGUS/SMM to MM are unknown.

My PhD project aims to unravel the genetic complexities of MM disease progression and tumour evolution using cutting edge next generation sequencing techniques on a rare collection of paired MGUS/SMM to MM patient sample set. High throughput genetic analysis is a novel concept in the MM space; with the “Initial genome sequencing and analysis of multiple myeloma” (Chapman et. al.) performed in 2011.

Determining genomic changes and clonal evolution models critical in the progression of MGUS/SMM to MM will help us identify biomarkers that can predict which people are prone to developing MM. Ultimately, we are hoping to develop new treatments to delay or cure the disease at the MGUS/SMM stage.

2017                            American Society of Haematology (ASH) Abstract Achievement Award

2017                            Adelaide Medical School Research Travel Award

2016                            Australian Society for Medical Research SA Meeting Best PhD Poster Award

2015                            Australian Mathematical Sciences Institute Travel Award

2015                            Florey Medical Research Foundation PhD Cancer Grant

2015                            Leukaemia Foundation of Australia PhD Scholarship

2014                            Australian Postgraduate Award Scholarship

  • Memberships

    Date Role Membership Country
    2016 - ongoing Member AusBiotech Australia
    2016 - ongoing Member Australian Society for Medical Research Australia

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