Adelaide Medical School
Faculty of Health and Medical Sciences
My primary research goal is to define the cognitive and functional impacts of obesity and nutrition on the brain. This research program has immediate relevance to a growing public health issue in Australia, where nearly a third of all children, and two-thirds of all adults, are overweight or obese. I use a multidimensional approach involving cutting-edge behavioural and neuropharmacology paradigms – including transgenic mice (Cre-lox, KI and KO models), in vivo fiber-photometry, chemogenetics, and optogenetics to study cognition and the functional effects of simulated ‘junk food’ diets in rodents; combined with molecular and chemical profiling of the post mortem rodent brain. This framework spans from individual gene expression, neurochemical alterations of neurons and their surrounding extracellular components (perineuronal nets), to long-lasting effects on neurodevelopment to provide a comprehensive picture of the neurobiological impact of obesity from the micro- to macro-scale.
I have built a strong reputation as an emerging thought leader in neuroscience and nutrition fields, demonstrated through numerous grants, awards and speaking invitations.
Date Position Institution name 2020 Senior Lecturer University of Adelaide 2018 - 2020 BrainsCAN Research Fellow Western University 2016 - 2018 Lecturer Royal Melbourne Institute of Technology University 2013 - 2016 Senior Research Associate UNSW Australia 2011 - 2013 Research Fellow University of Birmingham
Awards and Achievements
Date Type Title Institution Name Country Amount 2015 Award NSW Young Tall Poppy AIPS Australia —
Date Institution name Country Title 2011 Cardiff University United Kingdom PhD 2006 University of Birmingham United Kingdom BSc (Honours) 1st Class
Year Citation 2020 Bodden, C., Hannan, A., & Reichelt, A. (2020). Diet-Induced Modification of the Sperm Epigenome Programs Metabolism and Behavior. Trends in Endocrinology and Metabolism, 31(2), 131-149.
DOI Scopus4 WoS4 Europe PMC2
2020 Reichelt, A. (2020). Is loss of perineuronal nets a critical pathological event in Alzheimer's disease?. EBioMedicine, 59, 102946.
2020 Lowe, C., Morton, J., & Reichelt, A. (2020). Adolescent obesity and dietary decision making—a brain-health perspective. The Lancet Child and Adolescent Health, 4(5), 388-396.
2020 Loughman, A., Quinn, T., Nation, M., Reichelt, A., Moore, R., Van, T., . . . Tang, M. (2020). Infant microbiota in colic: Predictive associations with problem crying and subsequent child behavior. Journal of Developmental Origins of Health and Disease, 1-11.
DOI Scopus1 Europe PMC1
2020 Reichelt, A., Loughman, A., Bernard, A., Raipuria, M., Abbott, K., Dachtler, J., . . . Moore, R. (2020). An intermittent hypercaloric diet alters gut microbiota, prefrontal cortical gene expression and social behaviours in rats. Nutritional Neuroscience, 23(8), 613-627.
DOI Scopus6 WoS7 Europe PMC1
2019 Reichelt, A., Collett, J., Landmann, O., & Hallam, K. (2019). Assessing the impacts of daily Cannabis versus alcohol and methamphetamines on young Australians in youth AOD treatment. BMC Psychiatry, 19(1), 11 pages.
2019 Pham, X., Wright, D., Atapour, N., Chan, J., Watkins, K., Worthy, K., . . . Reser, D. (2019). Internal Subdivisions of the Marmoset Claustrum Complex: Identification by Myeloarchitectural Features and High Field Strength Imaging. Frontiers in Neuroanatomy, 13, 13 pages.
2019 Reichelt, A., Gibson, G., Abbott, K., & Hare, D. (2019). A high-fat high-sugar diet in adolescent rats impairs social memory and alters chemical markers characteristic of atypical neuroplasticity and parvalbumin interneuron depletion in the medial prefrontal cortex. Food and Function, 10(4), 1985-1998.
DOI Scopus6 WoS4
2019 Lowe, C., Reichelt, A., & Hall, P. (2019). The Prefrontal Cortex and Obesity: A Health Neuroscience Perspective. Trends in Cognitive Sciences, 23(4), 349-361.
DOI Scopus24 WoS17 Europe PMC4
2019 Pervolaraki, E., Tyson, A., Pibiri, F., Poulter, S., Reichelt, A., Rodgers, R., . . . Dachtler, J. (2019). The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice. Molecular Autism, 10(1), 13 pages.
DOI Scopus4 WoS4 Europe PMC2
2019 Reichelt, A., Hare, D., Bussey, T., & Saksida, L. (2019). Perineuronal Nets: Plasticity, Protection, and Therapeutic Potential. Trends in Neurosciences, 42(7), 458-470.
DOI Scopus11 WoS6 Europe PMC2
2019 Lowe, C., & Reichelt, A. (2019). Can magnetic resonance imaging reveal the neural signatures of dietary self-control?. Journal of Neuroscience, 39(4), 581-583.
2018 Reichelt, A., Stoeckel, L., Reagan, L., Winstanley, C., & Page, K. (2018). Dietary influences on cognition. Physiology and Behavior, 192, 118-126.
DOI Scopus9 WoS8 Europe PMC3
2018 Xu, T., & Reichelt, A. (2018). Sucrose or sucrose and caffeine differentially impact memory and anxiety-like behaviours, and alter hippocampal parvalbumin and doublecortin. Neuropharmacology, 137, 24-32.
DOI Scopus8 WoS9 Europe PMC2
2018 Buyukata, C., Vukalo, M., Xu, T., Khore, M., & Reichelt, A. (2018). Impact of high sucrose diets on the discrimination of spatial and object memories with overlapping features. Physiology and Behavior, 192, 127-133.
DOI Scopus2 WoS1
2017 Reichelt, A., & Rank, M. (2017). The impact of junk foods on the adolescent brain. Birth Defects Research, 109(20), 1649-1658.
DOI Scopus13 WoS12 Europe PMC5
2017 Reichelt, A., Westbrook, R., & Morris, M. (2017). Editorial: Impact of diet on learning, memory and cognition. Frontiers in Behavioral Neuroscience, 11, 2 pages.
DOI Scopus3 WoS3 Europe PMC3
2017 Wong, A., Dogra, V., & Reichelt, A. (2017). High-sucrose diets in male rats disrupt aspects of decision making tasks, motivation and spatial memory, but not impulsivity measured by operant delay-discounting. Behavioural Brain Research, 327, 144-154.
DOI Scopus4 WoS4
2017 Baker, K., Loughman, A., Spencer, S., & Reichelt, A. (2017). The impact of obesity and hypercaloric diet consumption on anxiety and emotional behavior across the lifespan. Neuroscience and Biobehavioral Reviews, 83, 173-182.
DOI Scopus14 WoS14 Europe PMC6
2017 Labouesse, M., Lassalle, O., Richetto, J., Iafrati, J., Weber-Stadlbauer, U., Notter, T., . . . Meyer, U. (2017). Hypervulnerability of the adolescent prefrontal cortex to nutritional stress via reelin deficiency. Molecular Psychiatry, 22(7), 961-971.
DOI Scopus28 WoS26 Europe PMC12
2016 Reichelt, A. (2016). Adolescent maturational transitions in the prefrontal cortex and dopamine signaling as a risk factor for the development of obesity and high fat/high sugar diet induced cognitive deficits. Frontiers in Behavioral Neuroscience, 10(OCT), 17 pages.
DOI Scopus30 WoS29 Europe PMC12
2016 Baker, K., & Reichelt, A. (2016). Impaired fear extinction retention and increased anxiety-like behaviours induced by limited daily access to a high-fat/high-sugar diet in male rats: Implications for diet-induced prefrontal cortex dysregulation. Neurobiology of Learning and Memory, 136(Dec), 127-138.
DOI Scopus25 WoS27 Europe PMC14
2016 Abbott, K., Morris, M., Westbrook, R., & Reichelt, A. (2016). Sex-specific effects of daily exposure to sucrose on spatial memory performance in male and female rats, and implications for estrous cycle stage. Physiology and Behavior, 162, 52-60.
DOI Scopus20 WoS20 Europe PMC12
2016 Reichelt, A., Morris, M., & Westbrook, R. (2016). Daily access to sucrose impairs aspects of spatial memory tasks reliant on pattern separation and neural proliferation in rats. Learning and Memory, 23(7), 386-390.
DOI Scopus13 WoS13 Europe PMC7
2016 Reichelt, A., Abbott, K., Westbrook, R., & Morris, M. (2016). Differential motivational profiles following adolescent sucrose access in male and female rats. Physiology and Behavior, 157, 13-19.
DOI Scopus33 WoS28 Europe PMC12
2016 Boitard, C., Parkes, S., Cavaroc, A., Tantot, F., Castanon, N., Layé, S., . . . Ferreira, G. (2016). Switching adolescent high-fat diet to adult control diet restores neurocognitive alterations. Frontiers in Behavioral Neuroscience, 10(NOV), 11 pages.
DOI Scopus23 WoS22 Europe PMC10
2015 Morris, M., Beilharz, J., Maniam, J., Reichelt, A., & Westbrook, R. (2015). Why is obesity such a problem in the 21st century? The intersection of palatable food, cues and reward pathways, stress, and cognition. Neuroscience and Biobehavioral Reviews, 58, 36-45.
DOI Scopus103 WoS103 Europe PMC56
2015 Reichelt, A., Maniam, J., Westbrook, R., & Morris, M. (2015). Dietary-induced obesity disrupts trace fear conditioning and decreases hippocampal reelin expression. Brain, Behavior, and Immunity, 43, 68-75.
DOI Scopus32 WoS31 Europe PMC18
2015 Exton-McGuinness, M., Lee, J., & Reichelt, A. (2015). Updating memories-The role of prediction errors in memory reconsolidation. Behavioural Brain Research, 278, 375-384.
DOI Scopus71 WoS67 Europe PMC38
2015 Reichelt, A., Killcross, S., Hambly, L., Morris, M., & Westbrook, R. (2015). Impact of adolescent sucrose access on cognitive control, recognition memory, and parvalbumin immunoreactivity. Learning and Memory, 22(4), 215-224.
DOI Scopus47 WoS46 Europe PMC27
2015 Reichelt, A., Westbrook, R., & Morris, M. (2015). Integration of reward signalling and appetite regulating peptide systems in the control of food-cue responses. British Journal of Pharmacology, 172(22), 5225-5238.
DOI Scopus19 WoS15 Europe PMC12
2014 Siette, J., Reichelt, A., & Westbrook, R. (2014). A bout of voluntary running enhances context conditioned fear, its extinction, and its reconsolidation. Learning and Memory, 21(2), 73-81.
DOI Scopus29 WoS29 Europe PMC19
2014 Reichelt, A. C., Morris, M. J., & Westbrook, R. (2014). Cafeteria diet impairs expression of sensory-specific satiety and stimulus-outcome learning. FRONTIERS IN PSYCHOLOGY, 5, 11 pages.
DOI WoS22 Europe PMC15
2013 Reichelt, A., & Lee, J. (2013). Memory reconsolidation in aversive and appetitive settings. Frontiers in Behavioral Neuroscience, 7(SEP), 18 pages.
DOI Scopus50 WoS45
2013 Martire, S., Tran, D., & Reichelt, A. (2013). Preventing binge eating with deep brain stimulation - Can compulsive eating be switched off?. Frontiers in Psychiatry, 4(DEC), 168.
2013 Reichelt, A., Good, M., & Killcross, S. (2013). Attenuation of acute d-amphetamine-induced disruption of conflict resolution by clozapine, but not α-flupenthixol in rats. Journal of Psychopharmacology, 27(11), 1023-1031.
DOI Scopus2 WoS2 Europe PMC2
2013 Humby, T., Eddy, J., Good, M., Reichelt, A., & Wilkinson, L. (2013). A novel translational assay of response inhibition and impulsivity: Effects of prefrontal cortex lesions, drugs used in ADHD, and serotonin 2C receptor antagonism. Neuropsychopharmacology, 38(11), 2150-2159.
DOI Scopus27 WoS25 Europe PMC21
2013 Reichelt, A., Killcross, S., Wilkinson, L., Humby, T., & Good, M. (2013). Transgenic expression of the FTDP-17 tau<inf>V337M</inf> mutation in brain dissociates components of executive function in mice. Neurobiology of Learning and Memory, 104, 73-81.
DOI Scopus6 WoS7 Europe PMC6
2013 Reichelt, A., & Lee, J. (2013). Over-expectation generated in a complex appetitive goal-tracking task is capable of inducing memory reconsolidation. Psychopharmacology, 226(4), 649-658.
DOI Scopus12 WoS11 Europe PMC7
2013 Reichelt, A., & Lee, J. (2013). Appetitive Pavlovian goal-tracking memories reconsolidate only under specific conditions. Learning and Memory, 20(1), 51-60.
DOI Scopus20 WoS19 Europe PMC12
2013 Reichelt, A., Exton-McGuinness, M., & Lee, J. (2013). Ventral tegmental dopamine dysregulation prevents appetitive memory destabilization. Journal of Neuroscience, 33(35), 14205-14210.
DOI Scopus32 WoS31 Europe PMC21
2012 Reichelt, A., Rodgers, R., & Clapcote, S. (2012). The role of neurexins in schizophrenia and autistic spectrum disorder. Neuropharmacology, 62(3), 1519-1526.
DOI Scopus63 WoS57 Europe PMC45
2011 Reichelt, A., Lin, T., Harrison, J., Honey, R., & Good, M. (2011). Differential role of the hippocampus in response-outcome and context-outcome learning: Evidence from selective satiation procedures. Neurobiology of Learning and Memory, 96(2), 248-253.
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Year Citation 2015 Reichelt, A., & Dachtler, J. (2015). The role of neurexins and neuroligins in autism. In The Molecular Basis of Autism (pp. 361-381).
2021 – 2025 National Health and Medical Research Council (NHMRC) Investigator Grant - Emerging Leader - Harnessing the extracellular matrix to fight obesity-induced cognitive impairment - $650K AUD
2020 – 2021 Neurosurgical Research Foundation (NSF) (CIA) - The role of diet in mediating the effect on cognitive impairment and cortical perineuronal net alterations following traumatic brain injury - $30K AUD. CIB Dr Frances Corrigan, CIC A/Prof Lyndsey Collins-Praino
2018 – 2020 BrainsCAN Tier 1 Fellowship - $225K CAD
2018 – 2021 Australian Research Council Discovery Project (Primary CI) - Functional impact of high energy diets on memory encoding. CI Prof Anthony Hannan (Florey Department, University of Melbourne) - $428K AUD
2018 – 2021 National Health and Medical Research Council (NHMRC) Project Grant (CIE) - Novel pharmacological strategies to treat cognitive dysfunction in COPD. CIA Prof Ross Vlahos - $872K AUD
2018 RMIT Transitional Research Grants for Teaching and Research Staff (CIB) - Early gastrointestinal microbiota determinants of child behaviour at age 2. CIA Dr Amy Loughman $10K AUD
2016 RMIT Strategic Equipment and Infrastructure Grant (Lead Investigator) - Touchscreen suite and digital stereotaxic equipment. $76K AUD
2015 UNSW Science Early Career Grant (Sole CI) - Impact of sucrose bingeing in adolescent rats on brain reward system connectivity. $7.3K AUD
2014 – 2017 Australian Research Council Discovery Early Career Research Award (Sole CI) - Does obesity alter psychological associations to food related cues, contexts and responses? $375K AUD
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