Dr Amy Dwyer

Dr Amy Dwyer

Research Fellow- DRMCRL

Adelaide Medical School

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.

Dr. Amy R. Dwyer is a Research Fellow at the Dame Roma Mitchell Cancer Research Laboratories (DRMCRL), Adelaide Medical School, University of Adelaide. In 2016 Dr Dwyer was awarded her PhD at the University of Western Australia under the supervision of Dr. Fiona J. Pixley, PhD, MBBS. Her research project was focused on elucidating Src Family Kinase signaling in tumour-associated macrophages (TAM) and how they mediate TAM motility; this work resulted in 4 first author and 3 co-author peer-reviewed publications. Dr. Dwyer subsequently undertook Postdoctoral Research training at the University of Minnesota Masonic Cancer Center, under the guidance of Dr. Carol A. Lange, PhD. Here, Dr. Dwyer focused on steroid and growth factor receptor signaling as part of unexpected or unique transcriptional complexes in breast cancer progression. In 2019 Dr. Dwyer moved to the DRMCRL where she continues to work on steroid receptor signaling in breast biology and cancer.

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  • Journals
    Year Citation
    2019 Dwyer, A., Truong, T., Diep, C., Hu, H., Hagen, K., & Lange, C. (2019). Phosphorylated Progesterone Receptor Isoforms Mediate Opposing Stem Cell and Proliferative Breast Cancer Cell Fates. Endocrinology, 160(2), 430-446.
    DOI Scopus4 WoS3 Europe PMC2
    2018 McGonigle, T. A., Dwyer, A. R., Greenland, E. L., Scott, N. M., Carter, K. W., Keane, K. N., . . . Hart, P. H. (2018). Reticulon-1 and Reduced Migration toward Chemoattractants by Macrophages Differentiated from the Bone Marrow of Ultraviolet-Irradiated and Ultraviolet-Chimeric Mice.. Journal of immunology (Baltimore, Md. : 1950), 200(1), 260-270.
    DOI WoS4 Europe PMC2
    2017 McGonigle, T. A., Dwyer, A. R., Greenland, E. L., Scott, N. M., Keane, K. N., Newsholme, P., . . . Hart, P. H. (2017). PGE2 pulsing of murine bone marrow cells reduces migration of daughter monocytes/macrophages in vitro and in vivo.. Experimental hematology, 56, 64-68.
    DOI WoS2 Europe PMC2
    2017 McGonigle, T. A., Keane, K. N., Ghaly, S., Carter, K. W., Anderson, D., Scott, N. M., . . . Hart, P. H. (2017). UV Irradiation of Skin Enhances Glycolytic Flux and Reduces Migration Capabilities in Bone Marrow-Differentiated Dendritic Cells.. The American journal of pathology, 187(9), 2046-2059.
    DOI WoS4 Europe PMC3
    2017 Dwyer, A. R., Greenland, E. L., & Pixley, F. J. (2017). Promotion of Tumor Invasion by Tumor-Associated Macrophages: The Role of CSF-1-Activated Phosphatidylinositol 3 Kinase and Src Family Kinase Motility Signaling.. Cancers, 9(6), 68.
    DOI WoS11 Europe PMC5
    2016 Dwyer, A. R., Ellies, L. G., Holme, A. L., & Pixley, F. J. (2016). A three-dimensional co-culture system to investigate macrophage-dependent tumor cell invasion.. Journal of biological methods, 3(3), e49.
    DOI
    2016 Dwyer, A. R., Mouchemore, K. A., Steer, J. H., Sunderland, A. J., Sampaio, N. G., Greenland, E. L., . . . Pixley, F. J. (2016). Src family kinase expression and subcellular localization in macrophages: implications for their role in CSF-1-induced macrophage migration.. Journal of leukocyte biology, 100(1), 163-175.
    DOI WoS8 Europe PMC9
    2014 Sullivan, A. R., & Pixley, F. J. (2014). CSF-1R Signaling in Health and Disease: A Focus on the Mammary Gland. JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA, 19(2), 149-159.
    DOI WoS13 Europe PMC9

CTSI Translational Research Development Program Fellow
University of Minnesota, Clinical and Translational Science Institute
2018 - 2020

PHAR2210 Ethical Conduct Tutorials
Department of Medicine and Pharmacology, University of Western Australia
2014 - 2016

PHAR3311 & 3321 Pharmacology Methods
Department of Medicine and Pharmacology, University of Western Australia
2012 - 2016

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  • Mentoring
    Date Topic Location Name
    2017 - ongoing MD/PhD Student University of Minnesota Carlos Perez Kerkvliet
    2014 - 2014 Honours Student University of Western Australia Eloise Greenland
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  • Committee Memberships
    Date Role Committee Institution Country
    2018 - ongoing Member Steering Committee Great Lakes Nuclear Receptor Conference 2018 University of Minnesota United States

  • Memberships
    Date Role Membership Country
    2019 - ongoing Member Australian Society for Medical Research Australia
    2016 - ongoing Member American Association of Cancer Research United States
    2016 - ongoing Member Endocrine Society United States
    2016 - ongoing Member Graduate Women in Science United States
    2013 - 2016 Member Australian Society of Cell and Developmental Biology Australia
  • Position: Research Fellow- DRMCRL
  • Phone: 83132946
  • Email: amy.dwyer@adelaide.edu.au
  • Campus: North Terrace
  • Building: Adelaide Health and Medical Sciences, floor 8
  • Room: WS8050.03
  • Org Unit: Medical Specialties
Connect With Me
External Profiles