Amita Ghadge

Amita Ghadge

Higher Degree by Research Candidate

Adelaide Medical School

Faculty of Health and Medical Sciences


Amita G Ghadge is a PhD candidate with the Breast Biology and Cancer Unit based at the Basil Hetzel Institute, The Queen Elizabeth Hospital. Her research investigates the impact of increased deposition of adipose tissue during puberty on mammary gland development and mammary cancer risk using mouse models.

Mammographic density is one of the most significant risk factors for breast cancer and attributes to 29% of all breast cancer diagnoses. Breast tissue with high mammographic density is characterised by increased abundance of fibroglandular tissue and reduced abundance of adipose tissue compared to breasts of low density. Epidemiological studies show that increased body mass index in adolescence is associated with low mammographic density as an adult and reduced lifetime risk of breast cancer. However, causal mechanisms are yet to be elucidated.

My PhD project investigates the impact of pubertal adipose tissue deposition on mammary gland density and mammary cancer development using mouse models. Outcomes of my research will provide new insights into the relationships of pubertal adipose tissue deposition, mammographic density and breast cancer risk.

  • Journals

    Year Citation
    2020 Ghadge, A. G., Dasari, P., Stone, J., Thompson, E. W., Robker, R. L., & Ingman, W. V. (2020). Pubertal mammary gland development is a key determinant of adult mammographic density. Seminars in Cell and Developmental Biology.
    DOI Scopus2
    2014 Ghadge, A. G., Karmakar, K., Devani, R. S., Banerjee, J., Mohanasundaram, B., Sinha, R. K., . . . Banerjee, A. K. (2014). Flower development, pollen fertility and sex expression analyses of three sexual phenotypes of Coccinia grandis. BMC Plant Biology, 14(1), 15 pages.
    DOI Scopus10 WoS10 Europe PMC6
  • Memberships

    Date Role Membership Country
    2019 - ongoing Member Endocrine Society of Australia Australia
    2019 - ongoing Member South Australian Breast Cancer Study Group Australia
  • Community Engagement

    Date Title Engagement Type Institution Country
    2018 - 2018 Basil Hetzel Institute exhibition booth at Science Alive 2018 Public Community Engagement Basil Hetzel Institute Australia
    2018 - 2018 Profile interview Public Community Engagement Basil Hetzel Institute, The Queen Elizabeth Hospital Australia
  • Presentation

    Date Topic Presented at Institution Country
    2019 - ongoing Heterogeneity of fatty acid metabolism in breast cancer cells underlies differential sensitivity palmitate-induced apoptosis Surgical Science Journal Club Surgical Science Journal Club, The University of Adelaide Australia
    2018 - ongoing Role of pubertal fatness in influencing breast development and breast cancer risk Research day Basil Hetzel Institute Australia
    2018 - 2018 Role of pubertal fatness in influencing breast development and breast cancer risk Breast/Endocrine Academic meeting 2018 South Australian Breast Cancer Study Group Australia

Connect With Me
External Profiles