Amita Ghadge

Amita Ghadge

Higher Degree by Research Candidate

Adelaide Medical School

Faculty of Health and Medical Sciences


Amita G Ghadge is a PhD candidate working with the Breast Biology and Cancer Unit, based at the Basil Hetzel Institute, The Queen Elizabeth Hospital. Her research is trying to answer why heavy teenage girls have lower risk of breast cancer.

Excess body weight, measured as high body mass index (BMI), is an important risk factor for breast cancer in women. But the way it impacts breast cancer risk varies by menopausal status. Postmenopausal women with high BMI have high risk of breast cancer, on contrary, teenage girls with high BMI have lower risk. The biological basis of this inverse association is still unknown.

My PhD project explores the role of fatness during puberty in influencing mammary gland development and breast cancer risk. As puberty is a critical life stage for breast development and breast cancer risk, we hypothesise that fatness during puberty is part of healthy breast development and reduces breast cancer risk that persists throughout adulthood, whereas obesity during adult life is unhealthy and induce inflammatory breast microenvironment and increase breast cancer risk.

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  • Journals

    Year Citation
    2014 Ghadge, A., Karmakar, K., Devani, R., Banerjee, J., Mohanasundaram, B., Sinha, R., . . . Banerjee, A. (2014). Flower development, pollen fertility and sex expression analyses of three sexual phenotypes of Coccinia grandis. BMC Plant Biology, 14(1), 15 pages.
    DOI Scopus6 WoS7 Europe PMC4
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  • Memberships

    Date Role Membership Country
    2019 - ongoing Member Endocrine Society of Australia Australia
    2019 - ongoing Member South Australian Breast Cancer Study Group Australia
  • Community Engagement

    Date Title Engagement Type Institution Country
    2018 - 2018 Basil Hetzel Institute exhibition booth at Science Alive 2018 Public Community Engagement Basil Hetzel Institute Australia
    2018 - 2018 Profile interview Public Community Engagement Basil Hetzel Institute, The Queen Elizabeth Hospital Australia
  • Presentation

    Date Topic Presented at Institution Country
    2019 - ongoing Heterogeneity of fatty acid metabolism in breast cancer cells underlies differential sensitivity palmitate-induced apoptosis Surgical Science Journal Club Surgical Science Journal Club, The University of Adelaide Australia
    2018 - ongoing Role of pubertal fatness in influencing breast development and breast cancer risk Research day Basil Hetzel Institute Australia
    2018 - 2018 Role of pubertal fatness in influencing breast development and breast cancer risk Breast/Endocrine Academic meeting 2018 South Australian Breast Cancer Study Group Australia

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