Ms Aimee Horsfall
Higher Degree by Research Candidate
Postgraduate Student
School of Physical Sciences
Faculty of Sciences
Aimee graduated from a Bachelor of Science (Molecular & Drug Design) in Chemistry at the University of Adelaide in 2015. She then went on to complete a Master of Philosophy in Chemical Science at the University of Adelaide, with a focus on constraining peptide secondary structure with a fluorescent linker, under the supervision of Professor Andrew Abell. Continuing under Professor Abell's guidance, Aimee is currently undertaking a PhD in Chemistry working on structurally constrained peptides and their interaction with proteins, with an aim to develop fluorescent peptide-based protein-protein interaction inhibitors. She is also a member of the ARC Centre of Excellence for Nanoscale Biophotonics (CNBP) and the Institute for Photonics & Advanced Sensing (IPAS).
The main research focus of my PhD encompasses synthesising peptides to probe protein-protein interaction sites. This information allows us to design and then synthesise constrained peptides, with restricted secondary structure, to act as competitive inhibitors of disease-related protein-protein interactions. I also look at how we can better detect these compounds within a biological system by using fluorescent peptide constraints as part of my work with the ARC Centre of Excellence for Nanoscale Biophotonics (CNBP) and the Institute for Photonics & Advanced Sensing (IPAS).
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Appointments
Date Position Institution name 2017 Chemistry Workshop Leader University of Adelaide, Adelaide 2015 Chemistry Practical Demonstrator University of Adelaide, Adelaide -
Education
Date Institution name Country Title 2017 University of Adelaide, Adelaide Australia Doctorate of Philosophy 2015 - 2017 University of Adelaide, Adelaide Australia Master of Philosophy 2012 - 2014 University of Adelaide, Adelaide Australia Bachelor of Science (Molecular & Drug Design) -
Research Interests
Aimee demonstrates undergraduate chemistry practical labs on a weekly basis during the University semesters, and is also involved with leading undergraduate chemistry workshops.
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