The nosocomial bacterial infections are a major cause of mortality mainly because overuse and/or inappropriate usage of antibiotic agents leads to the development of antimicrobial resistant bacteria. The antimicrobial resistance is less likely to occur for nanomaterials due to their nature and mechanism of fighting against bacteria. In my research study, two strategies were evaluated for the antimicrobial applications including nanostructured coatings and nanoparticles. My research project is focused on synthesizing of effective nanocomposites/nanomaterials with novel characteristics such as rapidness, multi-mode mechanisms and induction in the visible light range.