Adeline Bowen

Adeline Bowen

Adelaide Medical School

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.

My research focuses on studying the pathogenesis and evaluating various treatments in cellular and animal models of dementia. These include viral vector gene transfer, stem cell-based therapies and small molecule drugs for mucopolysaccharidosis (MPS) IIIA, an early-onset neurological lysosomal storage disorder for which there is no treatment. I also have an interest in mouse behavioural phenotyping, given the importance of determining the effect of any future therapy in delaying, improving or normalising clinical symptoms. Over this time, I have line managed one Research Scientist and co-supervised four Honours/PhD students. More recently, I have collaborated on a project investigating the role of the endosomal/lysosomal system in the late-onset dementia, Alzheimer’s Disease.

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  • Appointments
    Date Position Institution name
    2016 Affiliate Lecture The University of Adelaide
    2013 Research Officer South Australian Health and Medical Research Institute
    2007 - 2013 Post-doctoral Scientist SA Pathology (Women’s and Children’s Hospital site)
    2004 - 2004 Visiting Scientist Institut de Génétique Moléculaire de Montpellier
    2001 - 2003 Research Assistant Children’s Youth and Women’s Health Service

  • Awards and Achievements
    Date Type Title Institution Name Country Amount
    2018 Award SAHMRI Translation and Impact Award SAHMRI Australia —
    2017 Award Alice Davey Award The University of Adelaide Australia —

  • Language Competencies
    Language Competency
    English Can read, write, speak, understand spoken and peer review

  • Education
    Date Institution name Country Title
    — University of Adelaide Australia PhD
    — Flinders University Australia BBiotech (Hons)

  • Research Interests
    Animal Behaviour Gene and Molecular Therapy Neurosciences
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  • Current Higher Degree by Research Supervision (University of Adelaide)
    Date Role Research Topic Program Degree Type Student Load Student Name
    2018 Co-Supervisor The role of heterozygous lysomal storage disorder alleles as risk factors for dementia Doctor of Philosophy Doctorate Full Time Ms Lauren Sue Whyte

  • Other Supervision Activities
    Date Role Research Topic Location Program Supervision Type Student Load Student Name
    2017 - 2017 Principal Supervisor Evaluation of a novel drug for the treatment of childhood-onset dementia The University of Adelaide — Honours Full Time Sher Li Tan
    2010 - 2010 Co-Supervisor Assessment of the Migration of Donor-Derived Cells into the MPS IIIA Mouse Brain The University of Adelaide — Honours Full Time Noor Jannah Shamsani
    2010 - 2010 Co-Supervisor Investigation of olfactory ensheathing cells as a potential treatment for Mucopolysaccharidosis type IIIA The University of Adelaide — Honours Full Time Vonny Williem Oey
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