Post Doctoral - Researcher
Adelaide Medical School
Faculty of Health and Medical Sciences
Doctoral Research: Influence of Carbon Nanomaterial Exposure on Pro-constrictor Mechanisms during Pregnancy
Post-doctoral Research: Cardiovascular applications of nanoscales biophotonics and chemical sensors.
As a researcher of the ARC Centre of Excellence for Nanoscale Biophotonics and SAHMRI, Dr. Vidanapathirana's current research focus biological and biomedical applications of light based novel technologies in early detection and treatment of cardiovascular disease.
Three research projects are available for Honours or HDR (with Dr. Christina Bursill).
1. Biological sensing of cellular changes in atherosclerosis using novel nanoscale sensors. Our local and international collaborations provide access to novel nanoscale sensors with different imaging capabilities. This project broadly involves molecular and nanoscale fluorescent sensors, which will be tested first in in vitro and in vivo models, prior to future human/clinical applications in cardiovascular disease.
2. Novel platforms for wound healing and angiogenesis. This project incorporates bio-compatibility assessments and identifying properties of novel scaffolds and senor platforms to support wound healing.
3. Understanding the role of asialoglycoprotein receptor 1 (ASGR1) in the development and progression of atherosclerosis.
Date Position Institution name 2018 Internal Grant Funded Researcher University of Adelaide 2016 Post Doctoral Researcher SAHMRI 2014 - 2015 ARC Research Associate University of Adelaide 2014 - 2014 Research Assistant SAHMRI 2010 - 2013 Graduate Assistant East Carolina University 2009 - 2013 Lecturer University of Colombo 2009 - 2009 Medical Officer National Blood Transfusion Service 2008 - 2009 House Officer- General Medicine National Hospital of Sri Lanka 2006 - 2007 Research Assistant Sri Lanka Medical Association
Awards and Achievements
Date Type Title Institution Name Country Amount 2018 Nomination Oral presentation - Finalist, Early Career Researcher category Joint Annual Scientific Meeting of the Australian Atherosclerosis Society, High Blood Pressure Research Council of Australia and Australian Vascular Biology Society Australia — 2013 Fellowship Mid Atlantic Pre-doctoral Fellowship American Heart Association United States US$ 25000/year for two years 2013 Award Graduate Student Travel Award Society of Toxicology (SOT) United States US$ 1000 2013 Recognition Brody Graduate Association Student Highlight Brody School of Medicine, East Carolina University, NC United States — 2012 Award The Young Scientist Award South Asian Association of Physiologists Sri Lanka SLR 15000 2012 Award DMT Travel Award, Cardiovascular Toxicology Specialty Section Society of Toxicology United States US$ 1000 2010 Scholarship Graduate Assistantship Brody School of Medicine, East Carolina University United States — 2006 Award Prof. T. Visvanathan Gold Medal for Excellence in Clinical Obstetrics and Gynaecology at the final MBBS Faculty of Medicine, University of Colombo Sri Lanka — 2006 Award Dr. A.D. Wijesena Memorial Gold Medal for Obstetrics and Gynaecology at the final MBBS Faculty of Medicine, University of Colombo Sri Lanka — 2001 Scholarship ‘Mahapola Higher Education (Merit) Scholarship Mahapola’ Higher Education Scholarship Trust Fund Sri Lanka — 1999 Award Susan George Pulimood Memorial Award Visakha Vidyalaya, Colombo (High School) Sri Lanka — 1999 Award Mahagama Sekara Memorial Gold Medal Visakha Vidyalaya, Colombo (High School) Sri Lanka — 1999 Achievement All Island Master-Mind Championship (individual) Sirasa Sri Lanka SLR 5000
Language Competency English Can read, write, speak, understand spoken and peer review Sinhala; Sinhalese Can read, write, speak, understand spoken and peer review
Date Institution name Country Title 2010 - 2013 East Carolina University United States PhD (Physiology) 2001 - 2006 University of Colombo Sri Lanka MBBS
Date Title Institution Country 2015 Post-Doctoral Rsearcher SAHMRI Australia 2008 - 2008 Intern House Officer National Hospital of Sri Lanka Sri Lanka 2007 - 2008 Intern House Officer Lady Ridgeway Hospital for Children Sri Lanka
Date Title Institution name Country 2008 Medical Practitioner Sri Lanka Medical Council Sri Lanka
Year Citation 2019 Vidanapathirana, A., Pullen, B., Zhang, R., Duong, M., Goyne, J., Zhang, X., . . . Psaltis, P. (2019). A Novel Ruthenium-based Molecular Sensor to Detect Endothelial Nitric Oxide. Scientific Reports, 9(1), 16 pages.
2018 Vidanapathirana, A., Thompson, L., Herco, M., Odom, J., Sumner, S., Fennell, T., . . . Wingard, C. (2018). Acute intravenous exposure to silver nanoparticles during pregnancy induces particle size and vehicle dependent changes in vascular tissue contractility in Sprague Dawley rats. Reproductive Toxicology, 75, 10-22.
DOI Scopus4 WoS3 Europe PMC1
2017 Heng, S., Reineck, P., Vidanapathirana, A., Pullen, B., Drumm, D., Ritter, L., . . . Abell, A. (2017). Rationally designed probe for reversible sensing of zinc and application in cells. ACS Omega, 2(9), 6201-6210.
DOI Scopus6 WoS4
2016 Holland, N., Thompson, L., Vidanapathirana, A., Urankar, R., Lust, R., Fennell, T., & Wingard, C. (2016). Impact of pulmonary exposure to gold core silver nanoparticles of different size and capping agents on cardiovascular injury. Particle and Fibre Toxicology, 13(1), 21 pages.
DOI Scopus11 WoS10 Europe PMC7
2014 Vidanapathirana, A., Thompson, L., Mann, E., Odom, J., Holland, N., Sumner, S., . . . Wingard, C. (2014). PVP formulated fullerene (C60) increases Rho-kinase dependent vascular tissue contractility in pregnant Sprague Dawley rats. Reproductive Toxicology, 49, 86-100.
DOI Scopus17 WoS13 Europe PMC10
2014 Vidanapathirana, A., Thompson, L., Odom, J., Holland, N., Sumner, S., Fennell, T., . . . Wingard, C. (2014). Vascular tissue contractility changes following late gestational exposure to multi-walled carbon nanotubes or their dispersing vehicle in Sprague Dawley rats. Journal of Nanomedicine and Nanotechnology, 5(3), 1000201-1-1000201-15.
DOI Scopus9 Europe PMC1
2014 Wingard, C., Holland, N., Thompson, L., Brown, J., Lewin, A., Sumner, S., . . . Vidanapathirana, A. (2014). The need for reflective consideration of an integrative understanding of cardiovascular consequences to pvp formulated c60 exposure. Toxicological Sciences, 141(2), 327-328.
2014 Thompson, L., Urankar, R., Holland, N., Vidanapathirana, A., Pitzer, J., Han, L., . . . Wingard, C. (2014). C60 Exposure Augments Cardiac Ischemia/Reperfusion Injury and Coronary Artery Contraction in Sprague Dawley Rats. Toxicological Sciences, 138(2), 365-378.
2012 Vidanapathirana, A., Lai, X., Hilderbrand, S., Pitzer, J., Podila, R., Sumner, S., . . . Brown, J. (2012). Multi-walled carbon nanotube directed gene and protein expression in cultured human aortic endothelial cells is influenced by suspension medium. Toxicology, 302(2-3), 114-122.
DOI Scopus16 WoS13 Europe PMC12
Year Citation 2015 Vidanapathirana, A. K. (2015). Use of Nanotechnology in Pregnancy. In B. Bushan (Ed.), Encyclopaedia of Nanotechnology (pp. 11 pages). Springer.
Year Citation 2013 Vidanapathirana, A. K. (2013). Influence of Carbon Nanomaterial Exposure on Pro-constrictor Mechanisms during Pregnancy. (PhD Thesis).
1.Tom Simpson Trust Fund Grant, National Heart Foundation (2018)
2. Associate Investigator grant from the ARC Centre of Excellence in Nanoscale BioPhotonics (CNBP), University of Adelaide on the project “Biological Sensing of Changes in Atherosclerosis Using Novel Nanoscale Sensors” (August 2018).
3. Mid Atlantic Pre-doctoral Fellowship, American Heart Association (2013)
4. Society of Toxicology (SOT) Graduate Student Travel Award, SOT 52nd Annual Meeting, (March 2013, San Antonio, TX, USA)
5. DMT Travel Award, Cardiovascular Toxicology Specialty Section, Society of Toxicology annual meeting (March 2012, San Francisco, CA, USA)
1. Graduate Assistant - Department of Physiology, Brody School of Medicine in East Carolina University, Greenville, NC, USA (August 2010 - December 2013)
Training undergraduate and graduate students on vessel dissection and mounting on wire myography
Teaching assistant - Medical Physiology Course (Spring 2012)
2. Lecturer - Department of Physiology, Faculty of Medicine, University of Colombo, Sri Lanka (April 2009 to October 2013, on study leave from August 2010)
Medical Physiology - MBBS, BSc. (Pharmacy) and BSc. (Physiotherapy)
Lecturing, PBL tutor, laboratory sessions and assessments
Tutor for the Community and Family Attachment program (January - August 2010)
Convener of the Respiratory System module (March - August 2010)
Date Role Membership Country 2014 - ongoing Member Australian Atherosclerosis Society Australia 2013 - ongoing Member American Heart Assocataion United States 2011 - 2014 Member American Physiological Society United States 2011 - 2014 Member Society of Toxicology United States 2009 - ongoing Member Physiological Society of Sri Lanka Sri Lanka 2007 - ongoing Member Sri Lanka Medical Association Sri Lanka
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