Anak Dharmapatni

Dr Anak Dharmapatni

Postdoctoral Fellow

Adelaide Medical School

Faculty of Health and Medical Sciences

Eligible to supervise Masters and PhD - email supervisor to discuss availability.


Dr Anak Dharmapatni completed her PhD in the Discipline of Anatomy and Pathology, School of Medicine, the University of Adelaide in 2007, and MSc in Immunology, Allergy and arthritis, Flinders University in 2002, and MBBS and MD in 1991 and 1987 in Indonesia. Currently she is a post doctoral researcher and academic in the School of Medicine and Dentistry the University of Adelaide. She has obtained grants in arthritis and dental fields, published more than 20 papers and a regular reviewer for many scientific journals. She review grants for funding bodies such as NHMRC and United States-Israel Binational Science Foundation.

My research interests include human diseases associated with auto-immunity, in particular Rheumatoid Arthritis (RA) and systemic sclerosis. However, I am also interested in other forms of arthritis such as osteoarthritis and psoriatic arthritis. In recent years I have focused primarily on chronic inflammation-induced bone loss, such as chronic periodontitis and peri-implant osteolysis. With regards to cellular and molecular processes, my research focuses particularly on apoptosis, autophagy and osteoclast signaling. These are research strengths within the bone and joint lab, discipline of Anatomy and Pathology School of Medical Sciences. These research focuses have great potential for cross disciplinary studies and research collaborations, as demonstrated in a number of our publications.

I have also been successful in attaining various grants since 2012 until recently. These grants were awarded by the Arthritis Australia, the American Society of Bone and Mineral Research (ASBMR) and by the Australian Dental Research Foundation (ADRF).

I have collaborated with various research groups, both nationally and internationally, and continue to do so. Presently, I collaborate with the Colgate Australian Clinical Dental Research Centre, the Orthodontic Unit within the School of Dentistry, the Rheumatology Research Unit at the Repatriation Hospital, and Orthopaedics and Trauma at the University of Adelaide. I have also had international collaborations with Biogen Idec Inc., Cambridge Centre, Cambridge, Department of Medicine Imperial College London (Professor Gavin R. Screaton), Aegera Inc, Canada and SRI International, CA, USA.

 

I have contributed to my research fields by reviewing numerous scientific journals and grant proposals, and continue to do so. In the past few years I have been invited to review articles for various scientific journals such as Inflammopharmacology, Rheumatology (Oxford), Journal of Inflammation, Journal of Clinical Experimental Immunology, Journal of Histology and Histopathology, Journal of Periodontology, Journal of Cellular Physiology, Journal of Clinical Intervention of Aging, Journal of Human Immunology, Journal of Inflammation Research and Journal Pharma, International Journal of Molecular Sciences (IJMS), Calcified tissue International, PLOS one, Arthritis Research and Therapy. I have been a regular reviewer for the Journal of Periodontal Research, Journal of Human Immunology and Rheumatology (Oxford), which demonstrates my capacity to contribute to worldwide research.

National and international funding bodies have also invited me to review grant proposals. Some of these reviews include grant proposals from the United State-Israel Binational Foundation (BSF) for grant applications for funding the years 2013 and 2014. This demonstrates the recognition of my expertise by an International organization. More recently, I have been invited by the NHMRC to review a project grant for the 2014 project grant funding scheme.

 

Supervision of high degree research students is an integral part of my research activities. Currently, I am assigned to supervise postgraduate research students in both the School of Medical Sciences and the School of Dentistry.

 

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  • Appointments

    Date Position Institution name
    2017 Lecturer University of Adelaide
    2008 - 2015 Post Doctoral Researcher and casual teaching academic The University of Adelaide
  • Awards and Achievements

    Date Type Title Institution Name Country Amount
    2016 Research Award Arthritis Australia Project Grant 2016 The University of Adelaide Australia AUD$25,000
    2015 Research Award Marion A Simpson grant funded by the State of the Late Marion Alice Simpson. University of Adelaide Australia AUD $25,000
  • Language Competencies

    Language Competency
    English Can read, write, speak, understand spoken and peer review
  • Education

    Date Institution name Country Title
    2003 - 2007 The University of Adelaide Australia PhD
  • Research Interests

Date Project title Investigators Funding Body Amount
2016 Role of autophagy and apoptosis in the pathogenesis of inflammation and bone erosion in Chronic Periodontitis A Dharmapatni, D Haynes, M Barthold, T Crotti Australian Dental Research Foundation 17,390
2016 Pharmacologic Modulation of autophagy and apoptosis in Collagen Antibody Induced Arthritis model A Dharmapatni, T Crotti, D Haynes Arthritis Australia State/Territory Affiliate Arthritis SA 25,000
2015 Abrogating bone loss and inflammation in a mouse model of inflammatory arthritis T Crotti, A Dharmapatani, R Gibson, E Perilli Arthritis Australia Marion A Simpson Grant 25,000
2015 OSCAR A Serum Marker of Joint Erosion Enabling Treatment Modification T Crotti, A Dharmapatani, M Smith, M Wechalekar American Society for Bone and Mineral Research 50,000 USD
2014 Inhibiting autophagy to allow apoptosis to prevent joint damage in Rheumatoid Arthritis A Dharmapatani Arthritis Australia 10,000
2012 Investigating the potential use of IAP inhibitors for treatments of rheumatoid arthritis A Dharmapatani Arthritis Australia 15,000
2012 The Role of RUNX2 and VEGF during healing of periodontal ligament following hypothermal insult A Dharmapatani (CIC) Australian Dental Research Foundation 5,000
2010 Expression of Rheumatoid factor citrullinated protein and anti-citrullinated protein antibodies in normal and inflamed gingival tissue A Dharmapatani (CID) Australian Dental Research Foundation 5,000

2016 -           Lecturer Discipline of Anatomy and Pathology School of Medicine, Faculty of Health Sciences, The University of Adelaide

2014 - 2015 Tutor for Small Group discovery Experience (SGDE) part of Biology of Disease 2 (BOD2) for Bachelor of Health sciences

2009 -          Tutor for Dental and Clinical Science and Practice (DSP1 and 2) topics for 1st and 2nd year for Dentistry students at the University of Adelaide

2007 -          Guest lecturer of Biology of Human Disease (BOD2) with topic: “Bone and joint diseases” and “Infections in the developing countries”

2015            Guest lecturer for ENGR 7702, School of Computer Science, Engineering and Mathematics

2013 - 2014 Tutor for Human Biology, Anatomy and Physiology (Human Biology 1B) for Bachelor of Health Sciences

2007 - 2013 Demonstrator for Resource Sessions (integrated medical sciences including gross anatomy, histology and pathology) for 1st and 3rd year for Medicine students at the University of Adelaide

2010            Demonstrator for NURS 1102 (Anatomy and Physiology for Nursing) topic within the Nursing School at Flinders University

1996 - 2000 Lecturer Clinical Pathology for fifth semester/3rd year in the Faculty of Medicine at Udayana University, Bali, Indonesia

1996 - 2000 Lecturer Clinical Pathology for Bachelor of Nursing students at Udayana University, Bali Indonesia

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  • Past Higher Degree by Research Supervision (University of Adelaide)

    Date Role Research Topic Program Degree Type Student Load Student Name
    2016 - 2019 Co-Supervisor Pharmacological Modulation of Inflammation, Bone Loss and Pain in a Murine Model of Inflammatory Arthritis Doctor of Philosophy Doctorate Full Time Miss Bonnie Williams
    2013 - 2015 Co-Supervisor An investigation into the role of RANKL and sclerostin in dentoalveolar ankylosis using a rat model Doctor of Clinical Dentistry Doctorate Full Time Dr Shelley Joanne Coburn
    2011 - 2015 Co-Supervisor Targeting NF-kappaB and NFATc1 signalling to inhibit bone resorption in peri-prosthetic osteolysis Doctor of Philosophy Doctorate Full Time Mr Muhamad Syahrul Fitri Zawawi
    2010 - 2014 Co-Supervisor Osteoclast-associated Intracellular ITAM Signalling Molecules in Human Peri-implant Osteolysis and Rheumatoid Arthritis Doctor of Philosophy Doctorate Full Time Mr Ekram Alias
    2010 - 2011 Co-Supervisor The Role of the Osteocyte in Orthodontic Tooth Movement in the Rat Dento-Alveolar Complex Doctor of Clinical Dentistry Doctorate Full Time Dr Dinesh Sanmuganathan
    2010 - 2012 External Supervisor Insight into the Role of Periodontal Ligament Associated Protein 1 Asporin in the Maintenance of the Periodontal Ligament Using a Rat Ankylosis Model Doctor of Clinical Dentistry Doctorate Full Time Dr Wayne Chuo-Wei Chen
    2010 - 2013 Co-Supervisor Expression of Runt Related Transcription Factor 2 and Vascular Endothelial Growth Factor in the Pulp, Periodontal Ligament and Alveolar Bone: An Immunohistochemical Study Using a Rat Ankylotic Model Doctor of Clinical Dentistry Doctorate Full Time Dr Trudy Ann Stewart
  • Position: Postdoctoral Fellow
  • Phone: 83135986
  • Email: a.dharmapatni@adelaide.edu.au
  • Fax: 8313 4408
  • Campus: North Terrace
  • Building: Helen Mayo North, floor 3
  • Room: 3 08a
  • Org Unit: Medical Sciences

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