Rietie Venter

APrf Rietie Venter

Associate Professor

School of Pharmacy and Biomedical Sciences

College of Health

Eligible to supervise Masters and PhD - email supervisor to discuss availability.

Available For Media Comment.

I obtained my BSc Hons and Master’s degrees with distinction from the University of the Free State in South Africa. As top student in my BSc Hons class I secured an international scholarship to fund my PhD studies at the University of Leeds. After completing my PhD on membrane protein biochemistry at the University of Leeds in the beautiful Yorkshire Dales, I moved to Cambridge, where I spend twelve years doing research on multidrug transporters, first as a post-doc and later running my own research group as a Royal Society Dorothy Hodgkin Fellow in the Department of Pharmacology at the University of Cambridge. During this time, I was also appointed as College Lecturer in Robinson College, University of Cambridge, where I did small-group tutoring and teaching. Not content with moving continents once in a lifetime, I left the ancient buildings and immaculate college lawns of Cambridge for sun and sea in Australia after sixteen years in the UK. I joined the University of South Australia as Senior Lecturer and Head of Microbiology in the School of Pharmacy and Medical Sciences in December 2012.

My research focuses on antimicrobial resistance. ‘Superbugs’ are costing the medical and veterinary industry billions of dollars a year and antimicrobial resistance is one of the world’s most pressing health problems. According to the WHO we are fast approaching a post-antibiotic era where small injuries and minor infections will once again be fatal. Work in my laboratory is aimed at finding novel ways of treating infectious disease by characterising bacterial membrane proteins that are involved in drug resistance and/or virulence and on developing drugs that act on these targets. We are currently working on drug efflux pumps, iron transporters and cell division proteins in pathogenic bacteria. Most of our work focusses on the Gram-negative pathogen P. aeruginosa. This pathogen is associated with a range of life-threatening nosocomial infections and is the main cause of mortality in patients with cystic fibrosis. P. aeruginosa infections are hard to treat since this organism displays resistance against multiple classes of antimicrobials. Central to this bacterium’s high intrinsic drug resistance is the expression of drug efflux pumps and its ability to form antibiotic-tolerant biofilms.

Year Citation
2025 Blaikie, J. M., Sapula, S. A., Siderius, N. L., Hart, B. J., Amsalu, A., Leong, L. E. X., . . . Venter, H. (2025). Resistome Analysis of Klebsiella pneumoniae Complex from Residential Aged Care Facilities Demonstrates Intra-facility Clonal Spread of Multidrug-Resistant Isolates. Microorganisms, 12(4), 751.
DOI Scopus4 WoS5 Europe PMC6
2025 Sapula, S. A., Wang, Y., Hart, B. J., Whittall, J. J., & Venter, H. (2025). The continued evolution of the L2 cephalosporinase in Stenotrophomonas maltophilia: a key driver of beta-lactam resistance. Biochemical Journal, 482(3), BCJ20240478.
DOI
2025 Chen, H., Sapula, S. A., Turnidge, J., & Venter, H. (2025). The effect of commonly used non-antibiotic medications on antimicrobial resistance development in <i>Escherichia coli</i>. NPJ ANTIMICROBIALS AND RESISTANCE, 3(1), 15 pages.
DOI WoS3 Europe PMC2
2025 Nguyen, H. T., Puangseree, J., Nguyen, T. T., Nguyen, M. T., Leigh, C., Venter, H., . . . Ogunniyi, A. D. (2025). Gallium Liquid Metal Nanoparticles as Agents to Treat Multidrug-Resistant Bacterial Infections. Microbiologyopen, 14(5), 14 pages.
DOI
2025 Tesalona, S. D., Abulencia, M. F. B., Pineda Cortel, M. R. B., Sapula, S. A., Venter, H., & Lagamayo, E. N. (2025). Identification of a potential high-risk clone and novel sequence type of Carbapenem-Resistant Pseudomonas Aeruginosa in Metro Manila, Philippines. Antibiotics-Basel, 14(4, article no. 362), 1-17.
DOI
2025 Sharifian Gh, M., Norouzi, F., Sorci, M., Zaidi, T. S., Pier, G. B., Achimovich, A., . . . Laurie, G. W. (2025). Lacritin cleavage-potentiated targeting of iron - respiratory reciprocity promotes bacterial death. Journal of Biological Chemistry, 301(5, article no. 108455), 1-22.
DOI Europe PMC1
2025 Li, P., Li, C., Nie, L., Semple, S. J., Chai, W. C., Venter, H., . . . Xiang, L. (2025). HPLC quantification of fourteen flavonoids in <i>Sophora flavescens</i> Aiton extracts and component-effect relationship against <i>Acinetobacter baumannii</i>. NATURAL PRODUCT RESEARCH, 6 pages.
DOI
2024 Siderius, N. L., Sapula, S. A., Hart, B. J., Hutchings, J. L., & Venter, H. (2024). Enterobacter adelaidei sp. nov. Isolation of an extensively drug resistant strain from hospital wastewater in Australia and the global distribution of the species. Microbiological Research, 288, 1-15.
DOI Scopus3 WoS3 Europe PMC1
2024 Sharifian Gh, M., Norouzi, F., Sorci, M., Zaid, T. S., Pier, G. B., Achimovich, A., . . . Laurie, G. W. (2024). Targeting Iron - Respiratory Reciprocity Promotes Bacterial Death.. bioRxiv.
DOI
2024 Ogunniyi, A. D., Venter, H., & Blaskovich, M. A. T. (2024). New antibiotics to combat One Health AMR. Microbiology Australia, 45(2), 74-78.
DOI Scopus2 WoS2
2024 Roy Chowdhury, P., Alhamami, T., Venter, H., Veltman, T., Carr, M., Mollinger, J., . . . Djordjevic, S. P. (2024). Identification and evolution of ICE-PmuST394: a novel integrative conjugative element in Pasteurella multocida ST394.. The Journal of antimicrobial chemotherapy, 79(4), dkae040.
DOI Scopus11 WoS12 Europe PMC10
2024 Wang, Y., Sapula, S. A., Whittall, J. J., Blaikie, J. M., Lomovskaya, O., & Venter, H. (2024). Identification and characterization of CIM-1, a carbapenemase that adds to the family of resistance factors against last resort antibiotics. Communications Biology, 7(282), 1-13.
DOI Scopus5 WoS6 Europe PMC5
2024 Sapula, S. A., Hart, B. J., Siderius, N. L., Amsalu, A., Blaikie, J. M., & Venter, H. (2024). Multidrug-resistant Stenotrophomonas maltophilia in residential aged care facilities: An emerging threat. Microbiologyopen, 13(3), 18 pages.
DOI Scopus6 WoS7 Europe PMC7
2023 Pisoni, L. A., Semple, S. J., Liu, S., Sykes, M. J., & Venter, H. (2023). Combined structure- and ligand-based approach for the identification of inhibitors of AcrAB-TolC in Escherichia coli. ACS Infectious Diseases, 9(12), 2504-2522.
DOI Scopus6 WoS7 Europe PMC5
2023 Sapula, S. A., Amsalu, A., Whittall, J. J., Hart, B. J., Siderius, N. L., Nguyen, L., . . . Venter, H. (2023). The scope of antimicrobial resistance in residential aged care facilities determined through analysis of Escherichia coli and the total wastewater resistome.. Microbiol Spectr, 11(6), e0073123.
DOI Scopus4 WoS6 Europe PMC4
2023 Guo, T., Chen, Y., Chen, W., Semple, S. J., Gu, X., Polyak, S. W., . . . Ma, S. (2023). Design and synthesis of benzochromene derivatives as AcrB inhibitors for the reversal of bacterial multidrug resistance. European Journal of Medicinal Chemistry, 249(11548), 1-19.
DOI Scopus12 WoS11 Europe PMC7
2023 Alhamami, T., Roy Chowdhury, P., Venter, H., Veltman, T., Truswell, A., Abraham, S., . . . Trott, D. J. (2023). Genomic profiling of Pasteurella multocida isolated from feedlot cases of bovine respiratory disease.. Veterinary microbiology, 283(article no. 109773), 1-8.
DOI Scopus16 WoS8 Europe PMC7
2023 Nguyen, H. T., Venter, H., Woolford, L., Young, K. A., McCluskey, A., Garg, S., . . . Trott, D. J. (2023). Oral administration of a 2-aminopyrimidine robenidine analogue (NCL195) significantly reduces Staphylococcus aureus infection and reduces Escherichia coli infection in combination with sub-inhibitory colistin concentrations in a bioluminescent mouse model. Antimicrobial Agents and Chemotherapy, 67(10), e0042423-1-e0042423-13.
DOI
2023 Zhao, Y., Gericke, O., Li, T., Kjaerulff, L., Kongstad, K. T., Heskes, A. M., . . . Staerk, D. (2023). Polypharmacology-labeled molecular networking: an analytical technology workflow for accelerated identification of multiple bioactive constituents in complex extracts. Analytical Chemistry, 95(9), 4381-4389.
DOI Scopus13 WoS12 Europe PMC10
2023 Zhao, Y., Li, T., Kjaerulff, L., Venter, H., Coriani, S., Møller, B. L., . . . Staerk, D. (2023). Orthogonal reversed-phase C₁₈ and pentafluorophenyl HPLC separation for phytochemical profiling of serrulatanes in Eremophila denticulata. Journal of Natural Products, 86(12), 2638-2650.
DOI Scopus5 WoS5 Europe PMC3
2023 Honda, R., Kumar, M., Mardalisa, N., Wang, R., Venter, H., & Suzuki, S. (2023). Recommendations of key elements within an integrated monitoring framework of antimicrobial resistance for Asian countries. Environmental Science and Technology Letters, 11(1), 5-8.
DOI Scopus4 WoS5
2022 Sharifian Gh, M., Gadjeva, M. G., Venter, H., & Laurie, G. W. (2022). Lacritin bactericidal peptide N-104 targeting of inner membrane transporters FeoB and PotH (SpuG) individually absent in N-104 resistant strains of human opportunistic pathogen, P. aeruginosa PA14. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 36(S1), 1-2.
DOI
2022 Vargiu, A. V., Phan, G., Venter, H., & Broutin, I. (2022). The structural and functional study of efflux pumps belonging to the RND transporters family from gram-negative bacteria. Antibiotics, 11(4, article no. 429), 1-3.
DOI Scopus3 WoS2
2022 Alhamami, T., Low, W. Y., Ren, Y., Taylor, K., Khazandi, M., Veltman, T., . . . Trott, D. J. (2022). Antimicrobial susceptibility and genomic analysis of Histophilus somni isolated from cases of bovine respiratory disease in Autralian feedlot cattle.. Veterinary microbiology, 270(109460), 1-9.
DOI Scopus7 WoS6 Europe PMC5
2022 Chai, W. C., Whittall, J. J., Polyak, S. W., Foo, K., Li, X., Dutschke, C. J., . . . Venter, H. (2022). Cinnamaldehyde derivatives act as antimicrobial agents against Acinetobacter baumannii through the inhibition of cell division. Frontiers in Microbiology, 13(967949), 18 pages.
DOI Scopus23 WoS23 Europe PMC17
2022 Pi, H., Venter, H., Russell, C. C., Young, K. A., McCluskey, A., Page, S. W., . . . Trott, D. J. (2022). In Vitro Activity of Robenidine Analogues NCL259 and NCL265 against Gram-Negative Pathogens. Antibiotics, 11(10), 12 pages.
DOI Scopus2 WoS1
2022 Burns, A. L., Sleebs, B. E., Gancheva, M., McLean, K. T., Siddiqui, G., Venter, H., . . . Wilson, D. W. (2022). Targeting malaria parasites with novel derivatives of azithromycin. Frontiers in Cellular and Infection Microbiology, 12(article no. 1063407), 1-10.
DOI Scopus9 WoS8 Europe PMC7
2022 Nguyen, H. T., Venter, H., Woolford, L., Young, K., McCluskey, A., Garg, S., . . . Ogunniyi, A. D. (2022). Impact of a novel anticoccidial analogue on systemic staphylococcus aureus infection in a bioluminescent mouse model. Antibiotics, 11(1), 1-16.
DOI Scopus2 WoS2 Europe PMC2
2022 Roy Chowdhury, P., Alhamami, T., Venter, H., Veltman, T., Carr, M., Mollinger, J., . . . Djordjevic, S. P. (2022). Complete Genome Sequence of Pasteurella multocida Sequence Type 394, Isolated from a Case of Bovine Respiratory Disease in Australia.. Microbiol Resour Announc, 11(3), 1-2.
DOI Scopus6 WoS6 Europe PMC5
2022 Alhamami, T., Chowdhury, P. R., Gomes, N., Carr, M., Veltman, T., Khazandi, M., . . . Trott, D. J. (2022). Correction: Alhamami et al. First Emergence of Resistance to Macrolides and Tetracycline Identified in Mannheimia haemolytica and Pasteurella multocida Isolates from Beef Feedlots in Australia. Microorganisms 2021, 9, 1322. Microorganisms, 10(4), 825.
DOI Scopus2 Europe PMC1
2021 Sapula, S. A., Whittall, J. J., Pandopulos, A. J., Gerber, C., & Venter, H. (2021). An optimized and robust PEG precipitation method for detection of SARS-CoV-2 in wastewater. Science of the Total Environment, 785, 9 pages.
DOI Scopus70 WoS63 Europe PMC52
2021 Ogunniyi, A. D., Tenzin, S., Ferro, S., Venter, H., Pi, H., Amorico, T., . . . Trott, D. J. (2021). A pH-neutral electrolyzed oxidizing water significantly reduces microbial contamination of fresh spinach leaves. Food Microbiology, 93(103614), 1-9.
DOI Scopus20 WoS16 Europe PMC5
2021 Ogunniyi, A. D., Dandie, C. E., Brunetti, G., Drigo, B., Aleer, S., Hall, B., . . . Lombi, E. (2021). Neutral electrolyzed oxidizing water is effective for pre-harvest decontamination of fresh produce. Food Microbiology, 93, 10 pages.
DOI Scopus10 WoS7 Europe PMC4
2021 Nguyen, H. T., Venter, H., Veltman, T., Williams, R., Anne O'Donovan, L., Russell, C. C., . . . Trott, D. J. (2021). In vitro synergistic activity of NCL195 in combination with colistin against Gram-negative bacterial pathogens. International Journal of Antimicrobial Agents, 57(5), 106323-1-106323-13.
DOI Scopus20 WoS18 Europe PMC17
2021 Nguyen, H. T., O’Donovan, L., Venter, H., Russell, C. C., McCluskey, A., Page, S. W., . . . Ogunniyi, A. D. (2021). Comparison of two transmission electron microscopy methods to visualize drug-induced alterations of gram-negative bacterial morphology. Antibiotics, 10(3), 307.
DOI Scopus24 WoS24 Europe PMC23
2021 André, G. O., Borges, M. T., Assoni, L., Ferraz, L. F. C., Sakshi, P., Adamson, P., . . . Darrieux, M. (2021). Protective role of PhtD and its amino and carboxyl fragments against pneumococcal sepsis.. Vaccine, 39(27), 3626-3632.
DOI Scopus12 WoS10 Europe PMC10
2021 Alhamami, T., Chowdhury, P. R., Gomes, N., Carr, M., Veltman, T., Khazandi, M., . . . Trott, D. J. (2021). First emergence of resistance to macrolides and tetracycline identified in mannheimia haemolytica and pasteurella multocida isolates from beef feedlots in Australia. Microorganisms, 9(6), 1322.
DOI Scopus25 WoS25 Europe PMC19
2021 Nguyen, H. T., Morshed, M. T., Vuong, D., Crombie, A., Lacey, E., Garg, S., . . . Ogunniyi, A. D. (2021). Evaluation of Benzguinols as Next-Generation Antibiotics for the Treatment of Multidrug-Resistant Bacterial Infections. Antibiotics, 10(6), 727-1-727-17.
DOI Scopus1
2021 Pi, H., Ogunniyi, A. D., Savaliya, B., Nguyen, H. T., Page, S. W., Lacey, E., . . . Trott, D. J. (2021). Repurposing of the fasciolicide triclabendazole to treat infections caused by staphylococcus spp. and vancomycin-resistant enterococci. Microorganisms, 9(8), 1697-1-1697-20.
DOI Scopus10 WoS8 Europe PMC9
2021 Amsalu, A., Sapula, S. A., Whittall, J. J., Hart, B. J., Bell, J., Turnidge, J., & Venter, H. (2021). Taking AIM-(1) at carbapenem resistance in Pseudomonas aeruginosa. International Journal of Antimicrobial Agents, 58, 21003691.
DOI
2021 Amsalu, A., Sapula, S. A., Whittall, J. J., Hart, B. J., Bell, J. M., Turnidge, J., & Venter, H. (2021). Worldwide distribution and environmental origin of the Adelaide imipenemase (AIM-1), a potent carbapenemase in Pseudomonas aeruginosa. Microbial Genomics, 7(12), 000715-1-000715-11.
DOI Scopus13 WoS14 Europe PMC10
2021 Hu, S., Chai, W. C., Xu, L., Li, S., Jin, C., Zhu, R., . . . Xiang, L. (2021). Catecholic alkaloid sulfonates and aromatic nitro compounds from Portulaca oleracea and screening of their anti-inflammatory and anti-microbial activities. Phytochemistry, 181(112587), 1-11.
DOI Scopus17 WoS15 Europe PMC6
2021 Li, P., Chai, W. C., Wang, Z. Y., Tang, K. J., Chen, J. Y., Venter, H., . . . Xiang, L. (2021). Bioactivity-guided isolation of compounds from Sophora flavescens with antibacterial activity against Acinetobacter baumannii. Natural Product Research, 36(17), 4340-4348.
DOI Scopus15 WoS20 Europe PMC11
2021 Pacheco, T., Gomes, A. É. I., Siqueira, N. M. G., Assoni, L., Darrieux, M., Venter, H., & Ferraz, L. F. C. (2021). Sdia, a quorum-sensing regulator, suppresses fimbriae expression, biofilm formation, and quorum-sensing signaling molecules production in Klebsiella pneumoniae. Frontiers in Microbiology, 12(597735), 1-15.
DOI Scopus71 WoS62 Europe PMC46
2020 Dandie, C. E., Ogunniyi, A. D., Ferro, S., Hall, B., Drigo, B., Chow, C. W. K., . . . Lombi, E. (2020). Disinfection options for irrigation water: Reducing the risk of fresh produce contamination with human pathogens. CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY, 50(20), 2144-2174.
DOI Scopus39 WoS34
2020 Pi, H., Nguyen, H. T., Venter, H., Boileau, A. R., Woolford, L., Garg, S., . . . Ogunniyi, A. D. (2020). In vitro activity of robenidine Analog NCL195 in combination with outer membrane permeabilizers against gram-negative bacterial pathogens and impact on systemic gram-positive bacterial infection in mice. Front Microbiol, 11(1556), 1556.
DOI Scopus18 WoS17 Europe PMC16
2020 Gu, X., Pisoni, L. A., Wang, Y., Song, D., Sykes, M. J., Qin, Y., . . . Ma, S. (2020). Design and synthesis of novel 4-substituted quinazoline-2-carboxamide derivatives targeting AcrB to reverse the bacterial multidrug resistance. Bioorganic Chemistry, 105(104394), 1-16.
DOI Scopus10 WoS11 Europe PMC7
2020 Amsalu, A., Sapula, S. A., Lopes, M. D. B., Hart, B. J., Nguyen, A. H., Drigo, B., . . . Venter, H. (2020). Efflux pump-driven antibiotic and biocide cross-resistance in pseudomonas Aeruginosa isolated from different ecological Niches: a case study in the development of multidrug resistance in environmental hotspots. Microorganisms, 8(11), 1-18.
DOI Scopus88 WoS80 Europe PMC61
2020 Wang, Y., Alenazy, R., Gu, X., Polyak, S. W., Zhang, P., Sykes, M. J., . . . Ma, S. (2020). Design and structural optimization of novel 2H-benzo[h]chromene derivatives that target AcrB and reverse bacterial multidrug resistance. European Journal of Medicinal Chemistry, 213(113049), 1-20.
DOI Scopus28 WoS27 Europe PMC20
2020 Chai, W. C., Whittall, J. J., Song, D., Polyak, S. W., Ogunniyi, A. D., Wang, Y., . . . Venter, H. (2020). Antimicrobial action and reversal of resistance in MRSA by difluorobenzamide derivatives targeted at FtsZ. Antibiotics (Basel), 9(12), 1-22.
DOI Scopus14 WoS14 Europe PMC9
2020 Liu, Z., Zhang, P., Qin, Y., Zhang, N., Teng, Y., Venter, H., & Ma, S. (2020). Design and synthesis of aryl-substituted pyrrolidone derivatives as quorum sensing inhibitors. Bioorganic Chemistry, 105(article no. 104376), 1-9.
DOI Scopus21 WoS19 Europe PMC12
2020 Wang, Y., Alenzy, R., Song, D., Liu, X., Teng, Y., Mowla, R., . . . Ma, S. (2020). Structural optimization of natural product nordihydroguaretic acid to discover novel analogues as AcrB inhibitors. European Journal of Medicinal Chemistry, 186(111910), 18 pages.
DOI Scopus18 WoS16 Europe PMC10
2019 Ogunniyi, A. D., Dandie, C. E., Ferro, S., Hall, B., Drigo, B., Brunetti, G., . . . Lombi, E. (2019). Comparative antibacterial activities of neutral electrolyzed oxidizing water and other chlorine-based sanitizers. Scientific Reports, 9(1), 19955-1-19955-13.
DOI Scopus29 WoS26 Europe PMC10
2019 Jin, C., Alenazy, R., Wang, Y., Mowla, R., Qin, Y., Tan, J. Q. E., . . . Ma, S. (2019). Design, synthesis and evaluation of a series of 5-methoxy-2,3-naphthalimide derivatives as AcrB inhibitors for the reversal of bacterial resistance. Bioorganic and Medicinal Chemistry Letters, 29(7), 882-889.
DOI Scopus17 WoS15 Europe PMC11
2019 Sim, J. X. F., Khazandi, M., Pi, H., Venter, H., Trott, D. J., & Deo, P. (2019). Antimicrobial effects of cinnamon essential oil and cinnamaldehyde combined with EDTA against canine otitis externa pathogens. Journal of Applied Microbiology, 127(1), 99-108.
DOI Scopus38 WoS32 Europe PMC18
2019 Khazandi, M., Pi, H., Chan, W. Y., Ogunniyi, A. D., Sim, J. X. F., Venter, H., . . . Trott, D. J. (2019). In vitro antimicrobial activity of robenidine, ethylenediaminetetraacetic acid and polymyxin B nonapeptide against important human and veterinary pathogens. Frontiers in Microbiology, 10(837), 837-1-837-15.
DOI Scopus24 WoS22 Europe PMC20
2019 Imani Rad, H., Peeri, H., Amani, M., Mohammadnia, A., Ogunniyi, A. D., Khazandi, M., . . . Arzanlou, M. (2019). Allicin prevents the formation of Proteus-induced urinary crystals and the blockage of catheter in a bladder model in vitro. Microbial Pathogenesis, 132, 293-301.
DOI Scopus6 WoS4 Europe PMC3
2019 Venter, H. (2019). Reversing resistance to counter antimicrobial resistance in the World Health Organisation's critical priority of most dangerous pathogens. Bioscience reports, 29(4, article no. BSR20180474), 1-12.
DOI Scopus70 WoS72 Europe PMC52
2018 Wang, Y., Mowla, R., Ji, S., Guo, L., De Barros Lopes, M. A., Jin, C., . . . Venter, H. (2018). Design, synthesis and biological activity evaluation of novel 4-subtituted 2-naphthamide derivatives as AcrB inhibitors. European journal of medicinal chemistry, 143, 699-709.
DOI Scopus35 WoS35 Europe PMC27
2018 Bi, F., Ji, S., Venter, H., Liu, J., Semple, S. J., & Ma, S. (2018). Substitution of terminal amide with 1H-1,2,3-triazole: Identification of unexpected class of potent antibacterial agents. Bioorganic and medicinal chemistry letters, 28(5), 884-891.
DOI Scopus34 WoS33 Europe PMC18
2018 Khazandi, M., Al-Farha, A., Coombs, G., O'Dea, M., Pang, S., Trott, D., . . . Petrovski, K. (2018). Genomic characterization of coagulase-negative staphylococci including methicillin-resistant Staphylococcus sciuri causing bovine mastitis. Veterinary Microbiology, 219, 17-22.
DOI Scopus39 WoS36 Europe PMC23
2018 Liu, J., Ma, R., Bi, F., Zhang, F., Hu, C., Venter, H., . . . Ma, S. (2018). Novel 5-methyl-2-phenylphenanthridium derivatives as FtsZ-targeting antibacterial agents from structural simplification of natural product sanguinarine. Bioorganic and medicinal chemistry letters, 28(10), 1825-1831.
DOI Scopus25 WoS25 Europe PMC13
2018 Ogunniyi, A., Kopecki, Z., Hickey, E., Khazandi, M., Peel, E., Belov, K., . . . Trott, D. (2018). Bioluminescent murine models of bacterial sepsis and scald wound infections for antimicrobial efficacy testing. PLoS ONE, 13(7), e0200195-1-e0200195-13.
DOI Scopus27 WoS27 Europe PMC20
2018 Bi, F., Song, D., Zhang, N., Liu, Z., Gu, X., Hu, C., . . . Ma, S. (2018). Design, synthesis and structure-based optimization of novel isoxazole-containing benzamide derivatives as FtsZ modulators. European journal of medicinal chemistry, 159, 90-103.
DOI Scopus32 WoS31 Europe PMC20
2018 Mowla, R., Wang, Y., Ma, S., & Venter, H. (2018). Kinetic analysis of the inhibition of the drug efflux protein AcrB using surface plasmon resonance. Biochimica et Biophysica Acta - Biomembranes, 1860(4), 878-886.
DOI Scopus26 WoS23 Europe PMC18
2017 Mahbub, K. R., Krishnan, K., Andrews, S., Venter, H., Naidu, R., & Megharaj, M. (2017). Bio-augmentation and nutrient amendment decrease concentration of mercury in contaminated soil. Science of the total environment, 576, 303-309.
DOI Scopus46 WoS41 Europe PMC25
2017 Venter, H., Henningsen, M., & Begg, S. (2017). Antimicrobial resistance in healthcare, agriculture and the environment: The biochemistry behind the headlines. Essays in Biochemistry, 61(1), 1-10.
DOI Scopus106 WoS84 Europe PMC72
2017 Liu, F., Venter, H., Bi, F., Semple, S. J., Liu, J., Jin, C., & Ma, S. (2017). Synthesis and antibacterial activity of 5-methylphenanthridium derivatives as FtsZ inhibitors. Bioorganic and Medicinal Chemistry Letters, 27(15), 3399-3402.
DOI Scopus27 WoS28 Europe PMC14
2017 Khazandi, M., Deo, P., Ferro, S., Venter, H., Pi, H., Crabb, S., . . . Trott, D. (2017). Efficacy evaluation of a new water sanitizer for increasing the shelf life of Southern Australian King George Whiting and Tasmanian Atlantic Salmon fillets. Food Microbiology, 68, 51-60.
DOI Scopus37 WoS32 Europe PMC18
2017 Ogunniyi, A., Khazandi, M., Stevens, A., Sims, S., Page, S., Garg, S., . . . Trott, D. (2017). Evaluation of robenidine analog NCL195 as a novel broad-spectrum antibacterial agent. PLoS ONE, 12(9), e0183457-1-e0183457-23.
DOI Scopus39 WoS37 Europe PMC36
2017 Wang, Y., Mowla, R., Guo, L., Ogunniyi, A. D., Rahman, T., De Barros Lopes, M. A., . . . Venter, H. (2017). Evaluation of a series of 2-napthamide derivatives as inhibitors of the drug efflux pump AcrB for the reversal of antimicrobial resistance. Bioorganic and Medicinal Chemistry Letters, 27(4), 733-739.
DOI Scopus37 WoS33 Europe PMC27
2017 Bi, F., Guo, L., Wang, Y., Venter, H., Semple, S. J., Liu, F., & Ma, S. (2017). Design, synthesis and biological activity evaluation of novel 2,6-difluorobenzamide derivatives through FtsZ inhibition. Bioorganic and medicinal chemistry letters, 27(4), 958-962.
DOI Scopus32 WoS30 Europe PMC20
2017 Yan, M., Ma, R., Jia, L., Venter, H., & Ma, S. (2017). Synthesis and antibacterial activity of novel 3-O-descladinosylazithromycin derivatives. European journal of medicinal chemistry, 127, 874-884.
DOI Scopus9 WoS11 Europe PMC8
2017 Arzanlou, M., Chai, W. C., & Venter, H. (2017). Intrinsic, adaptive and acquired antimicrobial resistance in Gram-negative bacteria. Essays in Biochemistry, 61(1), 49-59.
DOI Scopus184 WoS163 Europe PMC125
2016 Qiang, S., Wang, C., Venter, H., Li, X., Wang, Y., Guo, L., . . . Ma, S. (2016). Synthesis and biological evaluation of novel FtsZ-targeted 3-arylalkoxy-2,6-difluorobenzamides as potential antimicrobial agents. Chemical Biology and Drug Design, 87(2), 257-264.
DOI Scopus12 WoS11 Europe PMC8
2016 Wang, Y., Venter, H., & Ma, S. (2016). Efflux pump inhibitors: a novel approach to combat efflux-mediated drug resistance in bacteria. Current drug targets, 17(6), 702-719.
DOI Scopus105 WoS97 Europe PMC82
2016 Seyedmohammad, S., Fuentealba, N. A., Marriott, R. A. J., Goetze, T. A., Edwardson, J. M., Barrera, N. P., & Venter, H. (2016). Structural model of FeoB, the iron transporter from Pseudomonas aeruginosa, predicts a cysteine lined, GTP-gated pore. Bioscience reports, 36(00322), 1-13.
DOI Scopus29 WoS29 Europe PMC31
2015 Venter, H., Mowla, R., Ohene Agyei, T., & Ma, S. (2015). RND-type drug efflux pumps from Gram-negative bacteria: molecular mechanism and inhibition. Frontiers in Microbiology, 6(377), 1-11.
DOI Scopus243 WoS223 Europe PMC179
2014 Ohene Agyei, T., Mowla, R., Rahman, T., & Venter, R. (2014). Phytochemicals increase the antibacterial activity of antibiotics by acting on a drug efflux pump0. Microbiology Open, 3(6), 885-896.
DOI Scopus100 WoS96 Europe PMC68
2014 Seyedmohammad, S., Born, D., & Venter, H. (2014). Expression, purification and functional reconstitution of FeoB, the ferrous iron transporter from Pseudomonas aeruginosa. Protein expression and purification, 101, 138-145.
DOI Scopus20 WoS20 Europe PMC21
2014 Du, D., Wang, Z., James, N. R., Voss, J. E., Klimont, E., Ohene Agyei, T., . . . Luisi, B. F. (2014). Structure of the AcrAB-TolC multidrug efflux pump. Nature, 509(7501), 512-515.
DOI Scopus522 WoS502 Europe PMC475
2012 Ohene Agyei, T., Lea, J. D., & Venter, H. (2012). Mutations in MexB that affect the efflux of antibiotics with cytoplasmic targets. FEMS Microbiology Letters, 333(1), 20-27.
DOI Scopus32 WoS33 Europe PMC23
2010 Welch, A., Awah, C. U., Jing, S., Van, V. H. W., & Venter, R. (2010). Promiscuous partnering and independent activity of MexB, the multidrug transporter protein from Pseudomonas aeruginosa. Biochemical Journal, 430(2), 355-364.
DOI Scopus46 WoS42 Europe PMC37
2009 Velamakanni, S., Lau, C. H. F., Gutmann, D. A. P., Venter, H., Barrera, N. P., Seeger, M. A., . . . van Heen, H. W. (2009). A multidrug ABC transporter with a taste for salt. Plos One, 4(7), 9 pages.
DOI Scopus36 WoS34 Europe PMC31
2009 Velamakanni, S., Lau, C. H. F., Gutmann, D. A. P., Venter, H., Barrera, N. P., Seeger, M. A., . . . van, H. H. W. (2009). A multidrug ABC transporter with a taste for salt. PLoS One, 4(7, article no. e6137), 1-9.
2009 Barrera, N. P., Isaacson, S. C., Zhou, M., Bavro, V. N., Welch, A., Schaedler, T. A., . . . Robinson, C. V. (2009). Mass spectrometry of membrane transporters reveals subunit stoichiometry and interactions. Nature methods, 6(8), 585-587.
DOI Scopus155 WoS152 Europe PMC143
2008 Venter, H., Velamakanni, S., Balakrishnan, L., & Van, V. H. W. (2008). On the energy-dependence of Hoechst 33342 transport by the ABC transporter LmrA. Biochemical pharmacology, 75(4), 866-874.
DOI Scopus43 WoS40 Europe PMC41
2007 BAPNA, A., FEDERICI, L., Venter, H., Velamakanni, S., Luisi, B. F., FAN, T., & Van Veen, H. W. (2007). Two proton translocation pathways in a secondary active multidrug transporter. Journal of molecular microbiology and biotechnology, 12(3-4), 197-209.
DOI Scopus20 WoS18 Europe PMC13
2006 Shilling, R. A., Venter, H., Velamakanni, S., Bapna, A., Woebking, B., Shahi, S., & van Veen, H. W. (2006). New light on multidrug binding by an ATP-binding-cassette transporter. Trends in Pharmacological Sciences, 27(4), 195-203.
DOI Scopus58 WoS58 Europe PMC43
2005 Woebking, B., Reuter, G., Shilling, R. A., Velamakanni, S., Shahi, S., Venter, H., . . . Van Veen, H. W. (2005). Drug-lipid A interactions on the Escherichia coli ABC transporter MsbA. Journal of Bacteriology, 187(18), 6363-6369.
DOI Scopus82 WoS81 Europe PMC75
2005 Shilling, R., Federici, L., Walas, F., Venter, H., Velamakanni, S., Woebking, B., . . . Van Veen, H. W. (2005). A critical role of a carboxylate in proton conduction by the ATP-binding cassette multidrug transporter LmrA. FASEB Journal, 19(12), 1698-1700.
DOI Scopus28 WoS26 Europe PMC24
2005 Janvilisri, T., Shahi, S., Venter, H., Balakrishnan, L., & Van Veen, H. W. (2005). Arginine-482 is not essential for transport of antibiotics, primary bile acids and unconjugated sterols by the human breast cancer resistance protein (ABCG2). Biochemical Journal, 385(2), 419-426.
DOI Scopus78 WoS69 Europe PMC58
2005 Venter, H., Shahi, S., Balakrishnan, L., Velamakanni, S., Bapna, A., Woebking, B., & Van Veen, H. W. (2005). Similarities between ATP-dependent and ion-coupled multidrug transporters. Biochemical Society Transactions, 33(5), 1008-1011.
DOI Scopus12 Europe PMC9
2004 Xie, H., Patching, S. G., Gallagher, M. P., Litherland, G. J., Brough, A. R., Venter, H., . . . Baldwin, S. A. (2004). Purification and properties of the Escherichia coli nucleoside transporter NupG, a paradigm for a major facilitator transporter sub-family. Molecular Membrane Biology, 21(5), 323-336.
DOI Scopus41 WoS44 Europe PMC40
2004 Balakrishnan, L., Venter, H., Shilling, R. A., & Van Veen, H. W. (2004). Reversible transport by the ATP-binding cassette multidrug export pump LmrA: ATP synthesis at the expense of downhill ethidium uptake. Journal of Biological Chemistry, 279(12), 11273-11280.
DOI Scopus60 WoS54 Europe PMC47
2003 Venter, H., Shilling, R. A., Velamakanni, S., Balakrishnan, L., & Van Veen, H. W. (2003). An ABC transporter with a secondary-active multidrug translocator domain. Nature, 426(6968), 866-870.
DOI Scopus106 WoS101 Europe PMC80
2003 Reuter, G., Janvilisri, T., Venter, H., Shahi, S., Balakrishnan, L., & Van Veen, H. W. (2003). The ATP binding cassette multidrug transporter LmrA and lipid transporter MsbA have overlapping substrate specificities. Journal of Biological Chemistry, 278(37), 35193-35198.
DOI Scopus133 WoS133 Europe PMC111
2003 Shilling, R. A., Balakrishnan, L., Shahi, S., Venter, H., & Van Veen, H. W. (2003). A new dimer interface for an ABC transporter. International Journal of Antimicrobial Agents, 22(3), 200-204.
DOI Scopus15 WoS14 Europe PMC11
2003 Janvilisri, T., Venter, H., Shahi, S., Reuter, G., Balakrishnan, L., & Van Veen, H. W. (2003). Sterol transport by the human breast cancer resistance protein (ABCG2) expressed in Lactococcus lactis. Journal of Biological Chemistry, 278(23), 20645-20651.
DOI Scopus156 WoS144 Europe PMC123
2002 Venter, H., Ashcroft, A. E., Keen, J. N., Henderson, P. J. F., & Herbert, R. B. (2002). Molecular dissection of membrane-transport proteins: Mass spectrometry and sequence determination of the galactose-H+ symport protein, GalP, of Escherichia coli and quantitative assay of the incorporation of [ring-2-13C]histidine and 15NH3. Biochemical Journal, 363(2), 243-252.
DOI Scopus30 WoS28 Europe PMC15
2000 Herbert, R. B., Venter, H., & Pos, S. (2000). Do mammals make their own morphine?. Natural Product Reports, 17(4), 317-322.
DOI Scopus18 WoS16 Europe PMC7
1999 Venter, H., Osthoff, G., & Litthauer, D. (1999). Purification and characterization of a metalloprotease from Chryseobacterium indologenes Ix9a and determination of the amino acid specificity with electrospray mass spectrometry. Protein Expression and Purification, 15(3), 282-295.
DOI Scopus33 WoS28 Europe PMC17

Year Citation
2005 Venter, H., Shahi, S., Balakrishnan, L., Velamakanni, S., Bapna, A., Woebking, B., & van Veen, H. W. (2005). Similarities between ATP-dependent and ion-coupled multidrug transports. In BIOCHEMICAL SOCIETY TRANSACTIONS Vol. 33 (pp. 1008-1011). SCOTLAND, Glasgow: PORTLAND PRESS LTD.
DOI WoS12
2004 Janvilisri, T., Shahi, S., Venter, H., Balakrishnan, L., & van Veen, H. W. (2004). The transport of antibiotics, lipids and bile salts by BCRP suggests a role in hepatobiliary secretion. In FASEB JOURNAL Vol. 18 (pp. A1201). DC, Washington: FEDERATION AMER SOC EXP BIOL.
2004 Reuter, G. D., Janvilisri, T., Venter, H., Shahi, S., Balakrishnan, L., & van Veen, H. W. (2004). The ATP-binding cassette multidrug transporter LmrA and lipid transporter MsbA have overlapping substrate specificities. In FASEB JOURNAL Vol. 18 (pp. A696). DC, Washington: FEDERATION AMER SOC EXP BIOL.
1999 Ward, A., O'Reilly, J., Rutherford, N. G., Ferguson, S. M., Hoyle, C. K., Palmer, S. L., . . . Henderson, P. J. F. (1999). Expression of prokaryotic membrane transport proteins in Escherichia coli. In Biochemical Society Transactions Vol. 27 (pp. 893-899). ENGLAND, UNIV KEELE, KEELE: PORTLAND PRESS.
DOI Scopus18 WoS18 Europe PMC16

Year Citation
2017 Pi, H., Khazandi, M., Ogunniyi, A. D., Page, S. W., Venter, H., & Trott, D. J. (2017). Characterization of a potential newclass of antimicrobial agent for Gram-negative bacteria. Poster session presented at the meeting of INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS. Taipei, TAIWAN: ELSEVIER SCIENCE BV.

Year Citation
2025 Chen, H., Sapula, S., Turnidge, J., & Venter, H. (2025). Commonly used non-antibiotic medications promote mutation frequency and antimicrobial resistance in <i>Escherichia coli</i>.
DOI
2024 Tesalona, S., Abulencia, M. F., Pineda-Cortel, M. R., Sapula, S., Venter, H., & Lagamayo, E. (2024). “Identification of potential high-risk clones of Carbapenem-Resistant<i>Pseudomonas aeruginosa</i>co-producing, KPC-2, VIM-2 and OXA-74 from tertiary hospitals in Metro Manila, Philippines”.
DOI
2023 Wang, Y., Sapula, S., Whittall, J., Blaikie, J., Lomovskaya, O., & Venter, H. (2023). Adding to the family of resistance factors against last resort antibiotics: Identification and characterization of a novel carbapenemase, CIM-1.
DOI

  • Turning antimicrobial resistance in residential aged care inside-out from the patient to facility level, MRFF - Targeted Call for Research - Antimicrobial Resistance, 26/06/2018 - 30/06/2024

  • LIXA in vitro and in vivo efficacy study, Neolixir Pty Ltd, 22/04/2024 - 30/06/2024

  • Reversing antibiotic resistance with efflux pump inhibitors, NHMRC - Project Grant, 01/01/2018 - 31/12/2021

  • Improving safety of vegetable produce through on‐farm sanitation, using Electrolysed Oxidising (EO) Water - VG15068, Hort Innovation, 01/06/2017 - 31/05/2020

  • Research Infrastructure Fund (RIF) Grant 2016 Round 2 - Biofilm Testing Facility, Adelaide Integrated Bioscience Laboratories, 28/11/2016 - 31/12/2017

Courses I teach

  • BIOL 2051 Microbiology (2025)
  • PHAR 2016 Dosage Form Design 2 (2025)
  • FOSC 3009 Product Development and Food Analysis (2024)

Programs I'm associated with

  • IHPC - Bachelor of Pharmacy (Honours)
  • IHPP - Bachelor of Pharmaceutical Science, Bachelor of Pharmacy (Honours)
  • IBMS - Bachelor of Medical Science

Date Role Research Topic Program Degree Type Student Load Student Name
2025 Principal Supervisor Establishing a cross-country multipronged approach to prepare for the pandemic of antimicrobial resistance (MAPP-AMR) Doctor of Philosophy Doctorate Full Time Mr Girija Roka
2023 Principal Supervisor 109420 - Limiting the risk for bacterial antimicrobial resistance: providing insight into the potential role of polypharmacy in antimicrobial resistance development Doctor of Philosophy Doctorate Full Time Mr Hanbiao Chen
2023 Principal Supervisor Preventing chronic infection in Cystic Fibrosis patients with a repurposed drug that inhibits antibiotic efflux pumps Doctor of Philosophy Doctorate Full Time Miss Sida Liu
2022 Principal Supervisor Characterisation of antimicrobial resistance factors in Chryseobacterium indologenes and Klebsiella oxytoca from healthcare environments and hospital wastewater  Doctor of Philosophy Doctorate Full Time Miss Yu Wang
2022 Principal Supervisor Combatting antimicrobial resistance through the development of responsible antimicrobial formulations with a reduced risk of causing resistance to clinically useful antibiotics Doctor of Philosophy Doctorate Full Time Mr Zifan Owen Xiang
2019 Principal Supervisor Risk factors in the development and dissemination of antimicrobial resistance in residential age care facilities Doctor of Philosophy Doctorate Part Time Mrs Naomi Siderius

Date Role Research Topic Program Degree Type Student Load Student Name
2017 - 2023 External Supervisor Phenotypic and Genetic Analysis of Antimicrobial Resistance in Bovine Respiratory Disease Pathogens from Australian Feedlots. Doctor of Philosophy Doctorate Part Time Ms Tamara Alhamami

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