Parul Mittal

Dr Parul Mittal

Research Associate

School of Pharmacy and Biomedical Sciences

College of Health

Eligible to supervise Masters and PhD (as Co-Supervisor) - email supervisor to discuss availability.

Available For Media Comment.

Parul Mittal is a Research Associate in the Mass spectrometry & Proteomics group, UniSA Clinical & Health Sciences. She obtained her PhD from the University of Adelaide in 2018 for her research in endometrial cancer and received a Dean’s Commendation for Doctoral Research Excellence.
She is a mass spectrometry specialist and has been engaged in many collaborative projects with universities, hospitals, and research centres across projects such as the analysis of cancer samples, organoids, spheroids, as well as the development of new data analysis methods.
Parul joined the University in 2020, after working as the Service and Facility officer at the Adelaide Proteomics Centre at the University of Adelaide for two years. There she was a vital part of a small and dedicated team operating the fee-for-service facility.

Year Citation
2026 Scanlan, J., Mittal, P., Lokman, N. A., Oehler, M. K., Hoffmann, P., & Klingler-Hoffmann, M. (2026). Toward Proteomic-Based Prediction of Ex Vivo Platinum Sensitivity in Ovarian Cancer Ascitic Cellular Aggregates: A Pilot Study. Journal of Proteome Research, 25(2), 828-841.
DOI
2026 Scanlan, J., Mittal, P., Oehler, M. K., Hoffmann, P., & Hoffmann, M. K. (2026). Proteomic Studies That Predict Patients’ Responses to High-Grade Serous Ovarian Cancer Treatments: A Systematic Review. Journal of Proteome Research, 25(2), 1126-1138.
DOI
2025 Ngai, Y. T., Lau, D., Mittal, P., & Hoffmann, P. (2025). Mini Review: Highlight of Recent Advances and Applications of MALDI Mass Spectrometry Imaging in 2024. Analytical Science Advances, 6(1), 11 pages.
DOI Scopus9 WoS7 Europe PMC7
2025 Lee, J. H., Sumer Bayraktar, Z., Mittal, P., Donnellan, L., Young, C., Rushworth, R. L., . . . Meyer, E. J. (2025). Mass spectrometric detection of neutrophil elastase cleaved corticosteroid binding globulin and its association with Asn347 site glycosylation, in septic shock patients. Clinica Chimica Acta, 567(120108), 1-8.
DOI Scopus1 WoS1 Europe PMC1
2025 Palethorpe, H. M., Shard, C., Scheer, K. G., Ryan, C. P., Fouladzadeh, A., Wenholz, D., . . . Gomez, G. A. (2025). An Optimized Explant Organoid Method for Preclinical Brain Tumor Research. NEURO-ONCOLOGY, 27(Supplement_5), v167.
DOI
2025 Noye, T. M., Mittal, P., Price, Z. K., Fewster, A., Williams, G., Pukala, T. L., . . . Ricciardelli, C. (2025). Identification of Proteins Associated with Ovarian Cancer Chemotherapy Resistance Using MALDI-MSI. International Journal of Molecular Sciences, 26(12), 5893.
DOI
2025 Ngai, Y. T., Young, C., Parkinson-Lawrence, E. J., Wimmer-Kleikamp, S., Mittal, P., Beard, H., . . . Hoffmann, P. (2025). Defining lung pathogenesis in a murine model of mucopolysaccharidosis Type I by proteomic analysis. Molecular Genetics and Metabolism, 146(1-2), 109231.
DOI
2024 Ngai, Y. T., Briggs, M. T., Mittal, P., Young, C., Parkinson-Lawrence, E., Klingler-Hoffmann, M., . . . Hoffmann, P. (2024). Mass spectrometry imaging protocol for spatial mapping of lipids, N-glycans and peptides in murine lung tissue. Rapid Communications in Mass Spectrometry, 38(9), e9721.
DOI Scopus6 WoS6 Europe PMC3
2024 Moxon, J. V., Pretorius, C., Trollope, A. F., Mittal, P., Klingler-Hoffmann, M., Hoffmann, P., & Golledge, J. (2024). A systematic review and in silico analysis of studies investigating the ischaemic penumbra proteome in animal models of experimental stroke. Journal of Cerebral Blood Flow and Metabolism, 44(10), 1709-1722.
DOI Scopus6 WoS7 Europe PMC6
2023 Arentz, G., Mittal, P., Klingler-Hoffmann, M., Condina, M. R., Ricciardelli, C., Lokman, N. A., . . . Hoffmann, P. (2023). Label-Free Quantification Mass Spectrometry Identifies Protein Markers of Chemotherapy Response in High-Grade Serous Ovarian Cancer. Cancers, 15(7), 14 pages.
DOI Scopus7 WoS8 Europe PMC7
2023 Sanyal, S. K., Pukala, T., Mittal, P., Reith, F., Brugger, J., Etschmann, B., & Shuster, J. (2023). From biomolecules to biogeochemistry: Exploring the interaction of an indigenous bacterium with gold. Chemosphere, 339, 139657-1-139657-12.
DOI Scopus1
2023 Kumarasamy, G., Ismail, M. N., Tuan Sharif, S. E., Desire, C., Mittal, P., Hoffmann, P., & Kaur, G. (2023). Protein profiling in human papillomavirus-associated cervical carcinogenesis: cornulin as a biomarker for disease progression. Current Issues in Molecular Biology, 45(4), 3603-3627.
DOI Scopus4 WoS3 Europe PMC3
2022 Lin, V. J. T., Hu, J., Zolekar, A., Salick, M. R., Mittal, P., Bird, J. T., . . . Wang, Y. C. (2022). Deficiency of N-glycanase 1 perturbs neurogenesis and cerebral development modeled by human organoids. Cell Death & Disease, 13(3, article no. 262), 1-13.
DOI Scopus13 WoS11 Europe PMC10
2022 Acland, M., Mittal, P., Arentz, G., Whitehead, F., Hoffmann, P., Klingler Hoffmann, M., & Oehler, M. K. (2022). A protocol for the acquisition of comprehensive proteomics data from single cases using formalin-fixed paraffin embedded sections. Methods and Protocols, 5(4, article no. 57), 1-17.
DOI Scopus3 WoS3 Europe PMC3
2021 Mittal, P., Briggs, M., Klingler-Hoffmann, M., Kaur, G., Packer, N. H., Oehler, M. K., & Hoffmann, P. (2021). Altered N-linked glycosylation in endometrial cancer. Analytical and Bioanalytical Chemistry, 413(10), 2721-2733.
DOI Scopus22 WoS22 Europe PMC23
2021 Enot, M. M., Weiland, F., Mittal, P., Hoffmann, P., Sillero-Mahinay, M., & Pukala, T. (2021). Differential proteome analysis of the leaves of lead hyperaccumulator, Rhoeo discolor (L. Her.) Hance. Journal of Mass Spectrometry, 56(4), e4689-1-e4689-11.
DOI Scopus10 WoS6 Europe PMC3
2021 Mittal, P., Condina, M. R., Klingler-Hoffmann, M., Kaur, G., Oehler, M. K., Sieber, O. M., . . . Hoffmann, P. (2021). Cancer tissue classification using supervised machine learning applied to maldi mass spectrometry imaging. Cancers, 13(21), 16 pages.
DOI Scopus31 WoS24 Europe PMC17
2020 Wang, C. R., Bubner, E. R., Jovcevski, B., Mittal, P., & Pukala, T. L. (2020). Interrogating the higher order structures of snake venom proteins using an integrated mass spectrometric approach.. J Proteomics, 216, 103680.
DOI Scopus22 WoS21 Europe PMC20
2020 Salman Sajid, M., Jovcevski, B., Mittal, P., Fatima, B., Hussain, D., Jabeen, F., . . . Najam-ul-Haq, M. (2020). Glycosylation heterogeneity and low abundant serum glycoproteins MS analysis by boronic acid immobilized Fe<inf>3</inf>O<inf>4</inf>@1,2-Epoxy-5-Hexene/DVB magnetic core shell nanoparticles. Microchemical Journal, 159, 8 pages.
DOI Scopus7 WoS8
2020 Boyle, S. T., Mittal, P., Kaur, G., Hoffmann, P., Samuel, M. S., & Klingler-Hoffmann, M. (2020). Uncovering tumor−stroma inter-relationships using MALDI Mass spectrometry imaging. Journal of Proteome Research, 19(10), 4093-4103.
DOI Scopus16 WoS16 Europe PMC14
2019 Briggs, M. T., Condina, M. R., Ho, Y. Y., Everest-Dass, A. V., Mittal, P., Kaur, G., . . . Hoffmann, P. (2019). MALDI mass spectrometry imaging of early- and late-stage serous ovarian cancer tissue reveals stage-specific N-glycans. Proteomics, 19(21-22), 1800482-1-1800482-11.
DOI Scopus54 WoS48 Europe PMC45
2019 Mittal, P., Price, Z. K., Lokman, N. A., Ricciardelli, C., Oehler, M. K., Klingler-Hoffmann, M., & Hoffmann, P. (2019). Matrix Assisted Laser Desorption/Ionization Mass Spectrometry Imaging (MALDI MSI) for monitoring of drug response in primary cancer spheroids. Proteomics, 19(21 - 22), e1900146-1-e1900146-4.
DOI Scopus22 WoS20 Europe PMC17
2019 Klingler-Hoffmann, M., Mittal, P., & Hoffmann, P. (2019). The Emerging Role of Cytoskeletal Proteins as Reliable Biomarkers.. Proteomics, 19(21-22), e1800483.
DOI Scopus16 WoS12 Europe PMC9
2019 Condina, M. R., Mittal, P., Briggs, M. T., Oehler, M. K., Klingler-Hoffmann, M., & Hoffmann, P. (2019). Egg white as a quality control in matrix assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI).. Analytical chemistry, 91(23), 14846-14853.
DOI Scopus13 WoS14 Europe PMC11
2019 Guo, Q., Ng, P. Q., Shi, S., Fan, D., Li, J., Zhao, J., . . . Searle, I. R. (2019). Arabidopsis TRM5 encodes a nuclear-localised bifunctional tRNA guanine and inosine-N1-methyltransferase that is important for growth. PLoS ONE, 14(11), 1-26.
DOI Scopus23 WoS22 Europe PMC21
2018 Acland, M., Mittal, P., Lokman, N., Klingler-Hoffmann, M., Oehler, M., & Hoffmann, P. (2018). Mass spectrometry analyses of multicellular tumor spheroids. Proteomics Clinical Applications, 12(3), 1700124-1-1700124-13.
DOI Scopus24 WoS22 Europe PMC21
2017 Mittal, P., Klingler-Hoffmann, M., Arentz, G., Winderbaum, L., Kaur, G., Anderson, L., . . . Oehler, M. (2017). Annexin A2 and alpha actinin 4 expression correlates with metastatic potential of primary endometrial cancer.. Biochim Biophys Acta, 1865(7), 846-857.
DOI Scopus25 WoS25 Europe PMC22
2016 Mittal, P., Klingler-Hoffmann, M., Arentz, G., Zhang, C., Kaur, G., Oehler, M., & Hoffmann, P. (2016). Proteomics of endometrial cancer diagnosis, treatment, and prognosis. Proteomics - Clinical Applications, 10(3), 217-229.
DOI Scopus25 WoS23 Europe PMC19
2016 Winderbaum, L., Koch, I., Mittal, P., & Hoffmann, P. (2016). Classification of MALDI-MS imaging data of tissue microarrays using canonical correlation analysis based variable selection. Proteomics, 16(11-12), 1731-1735.
DOI Scopus9 WoS9 Europe PMC7
2016 Mittal, P., Klingler-Hoffmann, M., Arentz, G., Winderbaum, L., Lokman, N., Zhang, C., . . . Hoffmann, P. (2016). Lymph node metastasis of primary endometrial cancers: associated proteins revealed by MALDI imaging. Proteomics, 16(11-12), 1793-1801.
DOI Scopus28 WoS28 Europe PMC27
2016 Zhang, C., Arentz, G., Winderbaum, L., Lokman, N., Klingler-Hoffmann, M., Mittal, P., . . . Hoffmann, P. (2016). MALDI mass spectrometry imaging reveals decreased CK5 levels in vulvar squamous cell carcinomas compared to the precursor lesion differentiated vulvar intraepithelial neoplasia. International Journal of Molecular Sciences, 17(7), 1088-1-1088-12.
DOI Scopus12 WoS9 Europe PMC11

Year Citation
2025 Scheer, K., Yeo, E., Shard, C., Lenin, S., Ormsby, R., Skarne, N., . . . Gomez, G. (2025). Growth rates of patient-derived tumor organoids reflect glioblastoma patients' heterogeneity in survival. In NEURO-ONCOLOGY Vol. 27 (pp. v479). OXFORD UNIV PRESS INC.
DOI

Year Citation
2026 Scanlan, J., Mittal, P., Washington, J., Young, C., Oehler, M. K., Hoffmann, P., & Klingler-Hoffmann, M. (2026). Ascites-Driven Modulation of Cell Phenotypes and Proteomes: Implications for Cancer Progression.
DOI
2024 Palethorpe, H. M., Shard, C., Scheer, K. G., Ryan, C. P., Fouladzadeh, A., Wenholz, D., . . . Gomez, G. A. (2024). An Optimized Explant Organoid Method for Preclinical Brain Tumor Research.
DOI
2018 Guo, Q., Ng, P. Q., Shi, S., Fan, D., Li, J., Wang, H., . . . Searle, I. R. (2018). <i>Arabidopsis</i>
TRM5 encodes a nuclear-localised bifunctional tRNA guanine and inosine-N1-methyltransferase that is important for growth.
DOI

Date Role Research Topic Program Degree Type Student Load Student Name
2026 Co-Supervisor Application of single cell spatial imaging for the identification if metastasis-associated markers in endometrial cancer - Doctorate Full Time Miss Krisha Chokshi
2024 Co-Supervisor Towards personalised treatment of Ovarian Cancer - Doctorate Full Time Mr Jack Scanlan
2023 Co-Supervisor Functional Analysis and Quantification of Biopharmaceuticals in Tissues by Mass Spectrometry Imaging - Doctorate Part Time Ms Sammi Ngai
2023 Co-Supervisor Mass spectrometry and spectroscopic analytical approaches for directed monoclonal antibody formulation development - Doctorate Full Time Abdulafeez Akinloye

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