APrf Chung Hoow Kok

Centre for Cancer Biology

College of Health

Eligible to supervise Masters and PhD - email supervisor to discuss availability.


A/Prof Chung Hoow Kok PhDA/Prof Kok is a highly experienced cancer biology, bioinformatics and artificial intelligence expert with over 10 years of experience in the field of hematological malignancies. He holds a Ph.D. in Medicine specialized in bioinformatics and cancer biology from University of Adelaide and has published numerous research papers in leading scientific journals. As a data scientist and bioinformatician, he has strong expertise on the cancer bioinformatics, predictive analytics, and artificial intelligence in cancer. His recent focus on personalised cancer medicine and bioinformatics, especially in the performance, integration, and interpretation of multi-omics of varying sizes and complexity, allowed him to establish many successful research projects bridging the divide between biology and bioinformatics with clinical significance, both nationally and internationally. Furthermore, his academic research expertise is further recognised through significant and consistent publication track record. A/Prof Kok has made significant contributions to the understanding of these diseases. He has also demonstrated expertise in machine learning and artificial intelligence, and has applied these techniques to predict treatment response and identify novel therapeutic targets. A/Prof Kok is dedicated to advancing the field of bioinformatics and artificial intelligence in hematological malignancies.

Date Position Institution name
2024 - ongoing Head of data and bioinformatics innovation South Australia Pathology
2023 - ongoing Affiliate Associate Professor University of Adelaide, Adelaide
2021 - 2023 Head of clinical data science (MDS/AML research) SAHMRI
2018 - 2023 Senior Bioinformatician (CML research) SAHMRI

Language Competency
Chinese (Cantonese) Can speak and understand spoken
Chinese (Mandarin) Can speak and understand spoken
English Can read, write, speak, understand spoken and peer review

Date Institution name Country Title
2010 University of Adelaide Australia PhD (Medicine)

Year Citation
2026 Maqsood, M., Toubia, J., Wadham, C., Shanmuganathan, N., Shahrin, N. H., Fernandes, A., . . . Branford, S. (2026). Enhanced Detection of Splice-Altering Variants in Hematologic Malignancies Using Targeted RNA-Sequencing Data. Journal of Molecular Diagnostics, 28(1), 39-52.
DOI
2025 Kusay, Y., Wu, D., De Sousa, S. M. C., Drogemuller, C. J., Coates, P. T., Kok, C. H., & Scott, H. S. (2025). Evaluating NGS variant callers in a challenging genomic context with a focus on the PRSS1-PRSS2 locus for hereditary pancreatitis. Gut, online, 1-3.
DOI
2025 Shanmuganathan, N., Yeung, D. T., Wadham, C., Fernandes, A., Maqsood, M., Shahrin, N. H., . . . Branford, S. (2025). Impact of ASXL1 at diagnosis in patients with CML receiving frontline potent TKIs: high risk of kinase domain mutations. Blood, 146(23), 2821-2832.
DOI
2025 Toubia, J., Kusay, Y., Maqsood, M., Warnock, N. I., Lawrence, D. M., Bracken, C. P., . . . Schreiber, A. W. (2025). TRanscriptome ANalysis of StratifiEd CohorTs (TRANSECT) enables automated assessment of global gene regulation linked to disparate expression in user defined genes and gene sets. NAR Genomics and Bioinformatics, 7(2), lqaf041-1-lqaf041-13.
DOI
2025 Wiseman, T., Spooner, M., Khanna, S., Hung, K., Toop, C., Kutyna, M. M., . . . Hiwase, D. K. (2025). RBC Transfusion Dependency Refines the Molecular International Prognostic Scoring System for Myelodysplastic Syndrome. Blood Advances, 9(16), 4244-4247.
DOI Scopus2 Europe PMC2
2025 Shah, M. V., Hung, K., Baranwal, A., Wechalekar, G., Al-Kali, A., Toop, C. R., . . . Hiwase, D. (2025). Validation of the 5th edition of the World Health Organization and International Consensus Classification guidelines for TP53-mutated myeloid neoplasm in an independent international cohort. Blood Cancer Journal, 15(1), 88-1-88-11.
DOI Scopus2 WoS2 Europe PMC1
2025 Bozkurt, C., Cildir, G., Aba, U., Erdogan, R. K., Warnock, N. I., Kok, C. H., & Erman, B. (2025). Comprehensive αβ T-Cell receptor repertoire analysis reveals a unique CD8 TCR landscape in DOCK8-deficient patients. Allergy, online(9), 1-12.
DOI
2025 Kok, C. H., Al-Kali, A., Thomas, D., He, R., Kutyna, M. M., Alkhateeb, H. B., . . . Hiwase, D. K. (2025). RAS Mutation Identifies a Poor Prognostic Molecular Subtype of Therapy-Related Myeloid Neoplasm. Blood Advances, 9(15), 3814-3818.
DOI
2025 Shah, M. V., Hung, K., Baranwal, A., Kutyna, M. M., Al-Kali, A., Toop, C., . . . Hiwase, D. K. (2025). Evidence-based risk stratification of myeloid neoplasms harboring TP53 mutations. Blood Advances, 9(13), 3370-3380.
DOI Scopus6 WoS4 Europe PMC5
2025 Baranwal, A., Langer, K. J., Gannamani, V., Rud, D., Cibich, A., Saygin, C., . . . Shah, M. V. (2025). Factors associated with survival after allogeneic transplantation for myeloid neoplasms harboring TP53 mutations. Blood Advances, 9(14), 3395-3407.
DOI Scopus6 WoS6 Europe PMC6
2025 Fairbank, J., Kok, C. H., Chhetri, R., Toop, C., Wall, M., Bardy, P., . . . Hiwase, D. (2025). Substantially improved survival for intermediate-risk AML: an Australian statewide network experience spanning 20 years. Blood Global Hematology, 1(1), 100004.
DOI
2025 Bayram Catak, F., Catak, M. C., Babayeva, R., Toubia, J., Warnock, N. I., Kok, C. H., . . . Baris, S. (2025). Ruxolitinib treatment ameliorates clinical, immunologic, and transcriptomic aberrations in patients with STAT3 gain-of-function disease. Journal of Allergy and Clinical Immunology, 55(3), 784-791.
DOI Scopus3 WoS3 Europe PMC3
2024 Kok, C. H., Saunders, V. A., Shanmuganathan, N., Liu, L., Irani, Y. D., Clarson, J., . . . Ross, D. M. (2024). Increased Inflammatory Cytokines in Plasma Are Associated with Sustained Treatment-Free Remission in Chronic Myeloid Leukaemia. BLOOD, 144(Supplement 1), 993-995.
DOI WoS2
2024 Kok, C. H., Yeung, D. T., & Hiwase, D. K. (2024). Special Issue 'advances in Molecular Pathogenesis and targeted therapies for Myeloid Neoplasms'. International Journal of Molecular Sciences, 25(4, article no. 2056), 1-5.
DOI Scopus1 WoS1 Europe PMC1
2024 Kok, C. H., Irani, Y., Clarson, J., Saunders, V., Dang, P., Shanmuganathan, N., . . . Hughes, T. P. (2024). CD302 predicts achievement of deep molecular response in chronic myeloid leukemia patients treated with imatinib. Blood Neoplasia, 1(2, article no. 100014), 1-11.
DOI Scopus1 Europe PMC1
2024 Wechalekar, M. D., Zhao, L. -P., Kutyna, M. M., Hong, L. E., Li, J., Hung, K., . . . Hiwase, D. K. (2024). Myeloid neoplasms arising after methotrexate therapy for autoimmune rheumatological diseases do not exhibit poor-risk molecular features. Blood Cancer Journal, 14(1), 116-1-116-5.
DOI Scopus1 WoS1 Europe PMC1
2024 Cildir, G., Aba, U., Pehlivan, D., Tvorogov, D., Warnock, N. I., Ipsir, C., . . . Erman, B. (2024). Defective kinase activity of IKKα leads to combined immunodeficiency and disruption of immune tolerance in humans. Nature Communications, 15(1), 9944-1-9944-18.
DOI Scopus1 WoS1 Europe PMC1
2024 Hong, L. E., Wechalekar, M. D., Kutyna, M. M., Small, A., Lim, K., Thompson-Peach, C. A., . . . Hiwase, D. K. (2024). IDH-Mutant Myeloid Neoplasms are Associated with Seronegative Rheumatoid Arthritis and Innate Immune Activation. Blood, 143(18), 1873-1877.
DOI Scopus11 WoS11 Europe PMC10
2023 Shanmuganathan, N., Wadham, C., Shahrin, N., Feng, J., Thomson, D., Wang, P., . . . Branford, S. (2023). Impact of additional genetic abnormalities at diagnosis of chronic myeloid leukemia for first-line imatinib-treated patients receiving proactive treatment intervention. Haematologica, 108(9), 2380-2395.
DOI Scopus19 WoS18 Europe PMC15
2023 Eşkazan, A. E., Kok, C. H., Yeung, D., Dalal, J., & Tiribelli, M. (2023). Editorial: advances in the treatment of chronic myeloid leukemia. Frontiers in Oncology, 13(article no. 1166588), 1-3.
DOI Scopus2 WoS1 Europe PMC2
2023 Baranwal, A., Chhetri, R., Yeung, D., Clark, M., Shah, S., Litzow, M. R., . . . Shah, M. V. (2023). Factors predicting survival following alloSCT in patients with therapy-related AML and MDS: a multicenter study.. Bone Marrow Transplant, 58(7), 769-776.
DOI Scopus12 WoS12 Europe PMC13
2023 Shah, M. V., Tran, E. N. H., Shah, S., Chhetri, R., Baranwal, A., Ladon, D., . . . Hiwase, D. K. (2023). TP53 mutation variant allele frequency of ≥10% is associated with poor prognosis in therapy-related myeloid neoplasms. Blood Cancer Journal, 13(1), 51-1-51-9.
DOI Scopus32 WoS32 Europe PMC30
2023 Irani, Y. D., Hughes, A., Kok, C. H., Clarson, J., Yeung, D. T., Ross, D. M., . . . Yong, A. S. M. (2023). Immune modulation in chronic myeloid leukaemia patients treated with nilotinib and interferon-alpha. British Journal of Haematology, 202(6), 1127-1136.
DOI Scopus6 WoS4 Europe PMC4
2023 Leow, B. C. S., Kok, C. H., Yeung, D. T., Hughes, T. P., White, D. L., & Eadie, L. N. (2023). The acquisition order of leukemic drug resistance mutations is directed by the selective fitness associated with each resistance mechanism. Sci Rep, 13(1), 1-12.
DOI Scopus2 WoS2 Europe PMC1
2023 Sharplin, K., Proudman, W., Chhetri, R., Tran, E. N. H., Choong, J., Kutyna, M., . . . Hiwase, D. (2023). A Personalized Risk Model for Azacitidine Outcome in Myelodysplastic Syndrome and Other Myeloid Neoplasms Identified by Machine Learning Model Utilizing Real-World Data. Cancers, 15(16), 1-14.
DOI Scopus4 WoS4 Europe PMC3
2023 Pagani, I. S., Shanmuganathan, N., Dang, P., Saunders, V. A., Grose, R., Kok, C. H., . . . Ross, D. M. (2023). Lineage-specific detection of residual disease predicts relapse in chronic myeloid leukemia patients stopping therapy. Blood, 142(25), 2192-2197.
DOI Scopus8 WoS8 Europe PMC7
2023 Kok, C. H., Saunders, V. A., Dang, P., Shanmuganathan, N., White, D., Branford, S., . . . Hughes, T. P. (2023). Adverse outcomes for chronic myeloid leukemia patients with splenomegaly and low in vivo kinase inhibition on imatinib. Blood Cancer Journal, 13(1), 1-9.
DOI Scopus2 WoS2 Europe PMC1
2023 Hiwase, D. K., Hahn, C. N., Tran, E. N. H., Chhetri, R., Baranwal, A., Al-Kali, A., . . . Shah, M. V. (2023). TP53 mutation in therapy-related myeloid neoplasm defines a distinct molecular subtype. Blood, 141(9), 1087-1091.
DOI Scopus30 WoS26 Europe PMC26
2023 Montarello, N., Leslie, A., Chhetri, R., Friel, O., Singhal, D., Ross, D. M., . . . Hiwase, D. K. (2023). Personalized risk model for predicting risk of acute coronary syndrome in patients with myelodysplastic syndromes.. Blood Advances, 7(13), 3032-3035.
DOI Scopus1 WoS1 Europe PMC1
2023 Irani, Y. D., Kok, C. H., Clarson, J., Shanmuganathan, N., Branford, S., Yeung, D. T., . . . Yong, A. S. (2023). Association of TIM-3 checkpoint receptor expression on T cells with treatment-free remission in chronic myeloid leukemia. Blood Advances, 7(11), 2364-2374.
DOI Scopus15 WoS14 Europe PMC13
2023 Kutyna, M. M., Loone, S., Saunders, V. A., White, D. L., Kok, C. H., & Hiwase, D. K. (2023). Solute Carrier Family 29A1 Mediates In Vitro Resistance to Azacitidine in Acute Myeloid Leukemia Cell Lines. International Journal of Molecular Sciences, 24(4), 3553-1-3553-14.
DOI Scopus3 WoS3 Europe PMC3
2022 Shah, M., Hahn, C. N., Tran, E. N. H., Sharplin, K. M., Chhetri, R., Baranwal, A., . . . Hiwase, D. (2022). <i>TP53</i> Mutation Status Defines a Distinct Clinicopathological Entity of Therapy-Related Myeloid Neoplasm, Characterized By Genomic Instability and Extremely Poor Outcome. BLOOD, 140(Supplement 1), 9798-9799.
DOI WoS2
2022 Gozzetti, A., Kok, C. H., & Li, C. F. (2022). Editorial: Molecular Mechanisms of Multiple Myeloma. Frontiers in Oncology, 12, 3 pages.
DOI Scopus1 WoS1 Europe PMC1
2022 Shah, M. V., Chhetri, R., Dholakia, R., Kok, C. H., Gangat, N., Alkhateeb, H. B., . . . Hiwase, D. (2022). Outcomes following venetoclax-based treatment in therapy-related myeloid neoplasms. American Journal of Hematology, 97(8), 1013-1022.
DOI Scopus10 WoS10 Europe PMC10
2022 Shanmuganathan, N., Wadham, C., Thomson, D., Shahrin, N. H., Vignaud, C., Obourn, V., . . . Branford, S. (2022). RNA-Based Targeted Gene Sequencing Improves the Diagnostic Yield of Mutant Detection in Chronic Myeloid Leukemia.. The Journal of molecular diagnostics : JMD, 24(7), 803-822.
DOI Scopus8 WoS6 Europe PMC5
2022 Lu, L., Kok, C. H., Dang, P., Branford, S., Saunders, V. A., Shanmuganathan, N., . . . Yeung, D. T. O. (2022). Highly sensitive droplet digital polymerase chain reaction for BCR::ABL1 messenger RNA identifies patients with chronic myeloid leukaemia with a low probability of achieving treatment-free remission. British Journal of Haematology, 198(3), 600-603.
DOI Scopus9 WoS8 Europe PMC7
2022 Kutyna, M. M., Kok, C. H., Lim, Y., Tran, E. N. H., Campbell, D., Paton, S., . . . Hiwase, D. K. (2022). A senescence stress secretome is a hallmark of therapy-related myeloid neoplasm stromal tissue occurring soon after cytotoxic exposure. Leukemia, 36(11), 2678-2689.
DOI Scopus17 WoS17 Europe PMC17
2022 Kutyna, M. M., Kok, C. H., Lim, Y., Campbell, D., Paton, S., Thompson-Peach, C. A. L., . . . Hiwase, D. (2022). Senolytic Therapy Can Reverse Senescent Bone Marrow Stroma of Therapy-Related Myeloid Neoplasm. Blood, 140(Supplement 1), 9755-9756.
DOI
2021 Fitter, S., Bradey, A. L., Kok, C. H., Noll, J. E., Wilczek, V. J., Venn, N. C., . . . Revesz, T. (2021). CKLF and IL1B transcript levels at diagnosis are predictive of relapse in children with pre‐B‐cell acute lymphoblastic leukaemia. British Journal of Haematology, 193(1), 171-175.
DOI Scopus5 WoS5 Europe PMC4
2021 García-Montolio, M., Ballaré, C., Blanco, E., Gutiérrez, A., Aranda, S., Gómez, A., . . . Di Croce, L. (2021). Polycomb Factor PHF19 Controls Cell Growth and Differentiation Toward Erythroid Pathway in Chronic Myeloid Leukemia Cells. Frontiers in Cell and Developmental Biology, 9, 13 pages.
DOI Scopus9 WoS9 Europe PMC10
2021 Tiong, I. S., Dillon, R., Ivey, A., Kuzich, J. A., Thiagarajah, N., Sharplin, K. M., . . . Wei, A. H. (2021). Clinical impact of NPM1-mutant molecular persistence after chemotherapy for acute myeloid leukemia. Blood Advances, 5(23), 5107-5111.
DOI Scopus35 WoS33 Europe PMC33
2020 Pagani, I. S., Dang, P., Saunders, V. A., Grose, R., Shanmuganathan, N., Kok, C. H., . . . Ross, D. M. (2020). Lineage of measurable residual disease in patients with chronic myeloid leukemia in treatment-free remission. Leukemia, 34(4), 1052-1061.
DOI Scopus42 WoS41 Europe PMC33
2020 Irani, Y. D., Hughes, A., Clarson, J., Kok, C. H., Shanmuganathan, N., White, D. L., . . . Yong, A. S. M. (2020). Successful treatment-free remission in chronic myeloid leukaemia and its association with reduced immune suppressors and increased natural killer cells. British Journal of Haematology, 191(3), 433-441.
DOI Scopus66 WoS62 Europe PMC59
2020 Li, Y., Chen, R., Yang, J., Mo, S., Quek, K., Kok, C. H., . . . Qin, J. J. (2020). Integrated Bioinformatics Analysis Reveals Key Candidate Genes and Pathways Associated With Clinical Outcome in Hepatocellular Carcinoma. Frontiers in Genetics, 11, 15 pages.
DOI Scopus19 WoS19 Europe PMC19
2020 Kutyna, M. M., Wee, L. Y. A., Paton, S., Cakouros, D., Arthur, A., Chhetri, R., . . . Hiwase, D. K. (2020). Therapy-Related Myeloid Neoplasm Has a Distinct Pro-Inflammatory Bone Marrow Microenvironment and Delayed DNA Damage Repair. Blood, 136(Supplement 1), 37-38.
DOI
2019 Kok, C. H., Yeung, D. T., Lu, L., Watkins, D. B., Leclercq, T. M., Dang, P., . . . Hughes, T. P. (2019). Gene expression signature that predicts early molecular response failure in chronic-phase CML patients on frontline imatinib. Blood Advances, 3(10), 1610-1621.
DOI Scopus31 WoS28 Europe PMC30
2018 Ross, D., Pagani, I., Shanmuganathan, N., Kok, C., Seymour, J., Mills, A., . . . Hughes, T. (2018). Long-term treatment-free remission of chronic myeloid leukemia with falling levels of residual leukemic cells. Leukemia, 32(12), 2572-2579.
DOI Scopus69 WoS63 Europe PMC57
2018 McClure, B., Heatley, S., Kok, C., Sadras, T., An, J., Hughes, T., . . . White, D. (2018). Pre-B acute lymphoblastic leukaemia recurrent fusion, EP300-ZNF384, is associated with a distinct gene expression. British Journal of Cancer, 118(7), 1000-1004.
DOI Scopus33 WoS29 Europe PMC26
2018 Paisitkriangkrai, S., Quek, K., Nievergall, E., Jabbour, A., Zannettino, A., & Kok, C. (2018). Co-fuse: a new class discovery analysis tool to identify and prioritize recurrent fusion genes from RNA-sequencing data. Molecular Genetics and Genomics, 293(5), 1217-1229.
DOI
2018 Lu, L., Kok, C. H., Saunders, V., Wang, J., McLean, J., Hughes, T. P., . . . White, D. L. (2018). Modelling ponatinib resistance in tyrosine kinase inhibitor-naïve and dasatinib resistant BCR-ABL1+ cell lines. Oncotarget, 9(78), 34735-34747.
DOI Scopus17 Europe PMC11
2017 Sadras, T., Kok, C., Perugini, M., Ramshaw, H., & D'Andrea, R. (2017). miR-155 as a potential target of IL-3 signaling in primary AML cells. Leukemia Research, 57, 57-59.
DOI Scopus8 WoS7 Europe PMC6
2017 Casolari, D., Nguyen, T., Butcher, C., Iarossi, D., Hahn, C., Bray, S., . . . D'Andrea, R. (2017). A novel, somatic, transforming mutation in the extracellular domain of epidermal growth factor receptor identified in myeloproliferative neoplasm. Scientific Reports, 7(1), 2467-1-2467-9.
DOI Scopus6 WoS6 Europe PMC7
2017 Pagani, I. S., Kok, C. H., Saunders, V. A., Van der Hoek, M. B., Heatley, S. L., Schwarer, A. P., . . . Ross, D. M. (2017). A method for next-generation sequencing of paired diagnostic and remission Samples to detect mitochondrial DNA mutations associated with leukemia. The Journal of molecular diagnostics : JMD, 19(5), 711-721.
DOI Scopus6 WoS5 Europe PMC7
2017 Sadras, T., Heatley, S., Kok, C., McClure, B., Yeung, D., Hughes, T., . . . White, D. (2017). A novel somatic JAK2 kinase-domain mutation in pediatric acute lymphoblastic leukemia with rapid on-treatment development of LOH. Cancer Genetics, 216-217, 86-90.
DOI Scopus13 WoS13 Europe PMC13
2017 Sadras, T., Heatley, S., Kok, C., Dang, P., Galbraith, K., McClure, B., . . . White, D. (2017). Differential expression of MUC4, GPR110 and IL2RA defines two groups of CRLF2-rearranged acute lymphoblastic leukemia patients with distinct secondary lesions. Cancer Letters, 408, 92-101.
DOI Scopus19 WoS21 Europe PMC18
2017 Heatley, S. L., Sadras, T., Kok, C. H., Nievergall, E., Quek, K., Dang, P., . . . White, D. L. (2017). High prevalence of relapse in children with Philadelphia-like acute lymphoblastic leukemia despite risk-adapted treatment. Haematologica, 102(12), e490-e493.
DOI Scopus56 WoS55 Europe PMC52
2017 Wang, J., Lu, L., Kok, C., Saunders, V., Goyne, J., Dang, P., . . . White, D. (2017). Increased peroxisome proliferator-activated receptor γ activity reduces imatinib uptake and efficacy in chronic myeloid leukemia mononuclear cells. Haematologica, 102(5), 843-853.
DOI Scopus12 WoS13 Europe PMC7
2016 Nievergall, E., Reynolds, J., Kok, C., Watkins, D., Biondo, M., Busfield, S., . . . White, D. (2016). TGF-α and IL-6 plasma levels selectively identify CML patients who fail to achieve an early molecular response or progress in the first year of therapy. Leukemia, 30(6), 1263-1272.
DOI Scopus48 WoS43 Europe PMC37
2015 Noll, J., Vandyke, K., Hewett, D., Mrozik, K., Bala, R., Williams, S., . . . Zannettino, A. (2015). PTTG1 expression is associated with hyperproliferative disease and poor prognosis in multiple myeloma. Journal of Hematology and Oncology, 8(1), 106-1-106-16.
DOI Scopus35 WoS35 Europe PMC32
2014 Sadras, T., Perugini, M., Kok, C., Iarossi, D., Heatley, S., Brumatti, G., . . . D'Andrea, R. (2014). Interleukin-3-mediated regulation of β-catenin in myeloid transformation and acute myeloid leukemia. Journal of Leukocyte Biology, 96(1), 83-91.
DOI Scopus18 WoS17 Europe PMC13
2014 Noll, J., Hewett, D., Williams, S., Vandyke, K., Kok, C., To, L., & Zannettino, A. (2014). SAMSN1 is a tumor suppressor gene in multiple myeloma. Neoplasia, 16(7), 572-585.
DOI Scopus41 WoS39 Europe PMC42
2014 Kok, C. H., Leclercq, T., Watkins, D. B., Saunders, V., Wang, J., Hughes, T. P., & White, D. L. (2014). Elevated PTPN2 expression is associated with inferior molecular response in de-novo chronic myeloid leukaemia patients. Leukemia, 28(3), 702-705.
DOI Scopus7 WoS6 Europe PMC7
2013 Brumatti, G., Salmanidis, M., Kok, C., Bilardi, R., Sandow, J., Silke, N., . . . Ekert, P. (2013). Hoxa9 regulated Bcl-2 expression mediates survival of myeloid progenitors and the severity of Hoxa9-dependent leukemia. Oncotarget, 4(11), 1933-1947.
DOI Scopus46 WoS43 Europe PMC40
2013 Perugini, M., Iarossi, D., Kok, C., Cummings, N., Diakiw, S., Brown, A., . . . D'Andrea, R. (2013). GADD45A methylation predicts poor overall survival in acute myeloid leukemia and is associated with IDH1/2 and DNMT3A mutations. Leukemia, 27(7), 1588-1592.
DOI Scopus22 WoS21 Europe PMC21
2013 Kok, C., Watkins, D., Leclercq, T., D'Andrea, R., Hughes, T., & White, D. (2013). Low GFI1 expression in white blood cells of CP-CML patients at diagnosis is strongly associated with subsequent blastic transformation. Leukemia, 27(6), 1427-1430.
DOI Scopus12 WoS13 Europe PMC12
2013 Diakiw, S., Perugini, M., Kok, C., Engler, G., Cummings, N., To, L., . . . D'Andrea, R. (2013). Methylation of KLF5 contributes to reduced expression in acute myeloid leukaemia and is associated with poor overall survival. British Journal of Haematology, 161(6), 884-888.
DOI Scopus17 WoS16 Europe PMC13
2013 Kok, C., Brown, A., Perugini, M., Iarossi, D., Lewis, I., & D'Andrea, R. (2013). The preferential occurrence of FLT3-TKD mutations in inv(16) AML and impact on survival outcome: A combined analysis of 1053 core-binding factor AML patients. British Journal of Haematology, 160(4), 557-559.
DOI Scopus9 WoS11 Europe PMC9
2012 Gagliardi, L., Ling, K., Kok, C., Carolan, J., Brautigan, P., Kenyon, R., . . . Scott, H. (2012). Genome-wide gene expression profiling identifies overlap with malignant adrenocortical tumours and novel mechanisms of inefficient steroidogenesis in familial ACTH-independent macronodular adrenal hyperplasia. Endocrine-Related Cancer, 19(3), 19-23.
DOI Scopus6 WoS6 Europe PMC5
2012 Wang, J., Hughes, T., Kok, C., Saunders, V., Frede, A., Groot Obbink, K., . . . White, D. (2012). Contrasting effects of diclofenac and ibuprofen on active imatinib uptake into leukaemic cells. British Journal of Cancer, 106(11), 1772-1778.
DOI Scopus21 WoS19 Europe PMC17
2012 Jabbour, A., Gordon, L., Daunt, C., Green, B., Kok, C., D'Andrea, R., & Ekert, P. (2012). p53-dependent transcriptional responses to interleukin-3 signaling. PLoS One, 7(2), 1-11.
DOI Scopus7 WoS7 Europe PMC6
2012 Bard-Chapeau, E., Jeyakani, J., Kok, C., Muller, J., Chua, B., Gunaratne, J., . . . Copeland, N. (2012). Ecotopic viral integration site 1 (EVI1) regulates multiple cellular processes important for cancer and is a synergistic partner for FOS protein in invasive tumors. Proceedings of the National Academy of Sciences of the United States of America, 109(6), 2168-2173.
DOI Scopus77 WoS74 Europe PMC73
2012 Diakiw, S., Kok, C., To, L., Lewis, I., Brown, A., & D'Andrea, R. (2012). The granulocyte-associated transcription factor Krüppel-like factor 5 is silenced by hypermethylation in acute myeloid leukemia. Leukemia Research, 36(1), 110-116.
DOI Scopus22 WoS21 Europe PMC21
2012 Brown, A., Salerno, D., Sadras, T., Engler, G., Kok, C., Wilkinson, C., . . . D'Andrea, R. (2012). The GM-CSF receptor utilizes β-catenin and Tcf4 to specify macrophage lineage differentiation. Differentiation, 83(1), 47-59.
DOI Scopus23 WoS21 Europe PMC20
2011 Hahn, C., Chong, C., Carmichael, C., Wilkins, E., Brautigan, P., Li, X., . . . Scott, H. (2011). Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia. Nature Genetics, 43(10), 1012-1019.
DOI Scopus543 WoS481 Europe PMC438
2010 Kok, C., Brown, A., Ekert, P., & D'Andrea, R. (2010). Gene expression analysis reveals HOX gene upregulation in trisomy 8 AML. Leukemia, 24(6), 1239-1243.
DOI Scopus13 WoS12 Europe PMC11
2009 Powell, J., Thomas, D., Barry, E., Kok, C., McClure, B., Tsykin, A., . . . Guthridge, M. (2009). Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML. Blood, 114(23), 4859-4870.
DOI Scopus53 WoS51 Europe PMC49
2009 Perugini, M., Kok, C., Brown, A., Wilkinson, C., Salerno, D., Young, S., . . . D'Andrea, R. (2009). Repression of Gadd45α by activated FLT3 and GM-CSF receptor mutants contributes to growth, survival and blocked differentiation. Leukemia, 23(4), 729-738.
DOI Scopus20 WoS19 Europe PMC21
2006 Brown, A., Wilkinson, C., Waterman, S., Kok, C., Salerno, D., Diakiw, S., . . . D'Andrea, R. (2006). Genetic regulators of myelopoiesis and leukemic signaling identified by gene profiling and linear modeling. Journal of Leukocyte Biology, 80(2), 433-447.
DOI Scopus39 WoS37 Europe PMC39

Year Citation
2024 Pagani, I. S., Krishnan, V., Ouyang, J., Kok, C. H., Chen, B., Page, E. C., . . . Ross, D. M. (2024). Imatinib-Sensitive Chronic Myeloid Leukaemia Is Associated with mtDNA Mutations and Reduced Oxphos Capacity. In BLOOD Vol. 144 (pp. 2715-2716). ELSEVIER.
DOI
2024 Spooner, M., Yu, J., Wiseman, T., Toop, C., Khanna, S., Kok, C. H., & Hiwase, D. (2024). Extended Rhesus and Kell Phenotype-Matched Red Blood Cell (RBC) Transfusions Reduce RBC Alloimmunization and RBC Transfusion Burden in Patients with Myeloid Neoplasm. In BLOOD Vol. 144 (pp. 5593-5594). ELSEVIER.
DOI
2024 Shah, M., Hung, K., Baranwal, A., Price, Z., Al-Kali, A., Toop, C., . . . Hiwase, D. (2024). The 66th ASH Annual Meeting Abstract Abstracts. In BLOOD Vol. 144 (pp. 3214). ELSEVIER.
2024 Wiseman, T., Spooner, M., Khanna, S., Hung, K., Toop, C., Singhal, D., . . . Hiwase, D. (2024). Dynamic Assessment of RBC-Transfusion Dependency (RBC-TD) Improves the Molecular International Prognostic. In BLOOD Vol. 144 (pp. 3209). ELSEVIER.
DOI WoS1
2024 Hung, K., Al-Kali, A., Toop, C., Patnaik, M. M., Price, Z., Kourelis, T., . . . Shah, M. (2024). <i>TP53</i>-Mutated Therapy-Related Myeloid Neoplasms Are Associated with a Long Latency and Are More Prevalent in Patients with Primary Hematological Cancers Compared to Solid Tumors. In BLOOD Vol. 144 (pp. 4594-4595). FL, Orlando: ELSEVIER.
DOI WoS2
2024 Branford, S., Fernandes, A., Wadham, C., Maqsood, M., Shahrin, N. H., Ross, D. M., . . . Shanmuganathan, N. (2024). Longitudinal Clonal Tracking Reveals That Early and Sensitive Detection of Blood Cancer-Related Gene Variants in Patients with Chronic Myeloid Leukemia Predicts Treatment Failure. In BLOOD Vol. 144 (pp. 996-997). FL, Orlando: ELSEVIER.
DOI
2024 Shanmuganathan, N., Wadham, C., Yeung, D., Shahrin, N. H., Fernandes, A., Maqsood, M., . . . Branford, S. (2024). Strong Association between Cancer Gene Variants at Diagnosis, Especially<i> ASXL1,</i> and Emergence of Kinase Domain Mutation-Driven Resistance in CML Patients Despite Frontline Treatment with More Potent BCR::ABL1 Inhibitors. In BLOOD Vol. 144 (pp. 992). FL, Orlando: ELSEVIER.
DOI WoS5
2024 Hiwase, D., Price, Z., Kok, C. H., Kutyna, M., Singhal, D., Shanmuganathan, N., . . . Scott, H. S. (2024). Pathogenic Germline Variants in the DNA Damage Repair Pathway Are Enriched in Patients with Hematologic Malignancies with Prior Exposure to Cytotoxic Therapies Compared to Patients with Multiple Cancers without Prior Exposure. In BLOOD Vol. 144 (pp. 4596-4597). FL, Orlando: ELSEVIER.
DOI
2023 Branford, S., Wadham, C., Shanmuganathan, N., Fernandes, A., Shahrin, N. H., Feng, J., . . . Hughes, T. P. (2023). Age-Related Clonal Hematopoiesis Mutations Detected at the Time of Stopping Tyrosine Kinase Inhibitor Therapy Predict the Achievement of Treatment-Free Remission for Patients with CML. In BLOOD Vol. 142 (pp. 5 pages). CA, San Diego: ELSEVIER.
DOI WoS5
2023 Hong, L. E., Kok, C. H., Kutyna, M., Li, J. J., Chhetri, R., Ross, D. M., . . . Hiwase, D. (2023). High Prevalence of IDH Mutation in Myeloid Neoplasm with Concomitant Autoimmune Rheumatic Disorders. In BLOOD Vol. 142 (pp. 4 pages). CA, San Diego: ELSEVIER.
DOI
2023 Hiwase, D., Baranwal, A., Shah, S., Kutyna, M., Hahn, C. N., Abdelmajid, M., . . . Shah, M. V. (2023). Single-Hit TP53 mut Is Associated with Poor Outcomes in Therapy-Related but Not De Novo Myelodysplastic Syndromes: Importance of Clinical History. In BLOOD Vol. 142 (pp. 4 pages). CA, San Diego: ELSEVIER.
DOI
2023 Shah, M. V., Kutyna, M., Shah, S., Tran, E. N. H., Baranwal, A., Ladon, D., . . . Hiwase, D. (2023). Comparison of World Health Organization and International Consensus Classification Guidelines for Myeloid Neoplasms Harboring TP53-Mutations Using an Independent International Cohort. In BLOOD Vol. 142 (pp. 4 pages). CA, San Diego: ELSEVIER.
DOI WoS4
2022 Radich, J. P., Kok, C. H., Chelysheva, E. Y., Cortes, J. E., Jiang, Q., Mauro, M., . . . Hughes, T. (2022). A Risk Model for CML Patients with COVID-19: Importance of Molecular Response in the Context of Age, Comorbidities and Country Income. In BLOOD Vol. 140 (pp. 9617-9619). LA, New Orleans: ELSEVIER.
DOI WoS2
2022 Branford, S., Shanmuganathan, N., Wadham, C., Shahrin, N. H., Fernandes, A., Feng, J., . . . Hughes, T. (2022). Clonal Hematopoiesis Detected at the Time of Tyrosine Kinase Inhibitor Cessation Is Associated with Delayed Molecular Recurrence after Treatment-Free Remission in Patients with CML. In BLOOD Vol. 140 (pp. 3916-3917). LA, New Orleans: ELSEVIER.
DOI WoS1
2022 Kok, C. H., Tran, E. N. H., Ladon, D., Chhetri, R., Baranwal, A., Sharplin, K. M., . . . Hiwase, D. (2022). Personalized Prediction Model to Risk Stratify Patients with Therapy-Related Myeloid Neoplasms. In BLOOD Vol. 140 (pp. 6962-6963). LA, New Orleans: ELSEVIER.
DOI
2021 Kutyna, M., Kok, C. H., Wee, L. Y., Paton, S., Chhetri, R., Thomas, D., . . . Hiwase, D. (2021). BONE MARROW MICROENVIRONMENT IN THERAPY-RELATED MYELOID NEOPLASMS IS DISTINCT FROM OTHER MYELOID NEOPLASMS, PROBABLY DRIVEN BY PRIOR CYTOTOXIC THERAPY. In LEUKEMIA RESEARCH Vol. 108 (pp. S18-S19). PERGAMON-ELSEVIER SCIENCE LTD.
2021 Pagnano, K. B., Kok, C. H., Mauro, M. J., Cortes, J. E., Evans, N., Jiang, Q., . . . Hughes, T. P. (2021). COVID-19 in Patients with Chronic Myeloid Leukemia: Poor Outcomes for Patients with Comorbidities, Older Age, Advanced Phase Disease, and Those from Low-Income Countries: An Update of the Candid Study. In BLOOD Vol. 138 (pp. 4 pages). GA, Atlanta: ELSEVIER.
DOI WoS3
2021 Kutyna, M. M., Kok, C. H., Paton, S., Cakouros, D., Arthur, A., Hughes, T. P., . . . Hiwase, D. (2021). Distinct Senescent Bone Marrow Microenvironment in Therapy-Related Myeloid Neoplasms. In BLOOD Vol. 138 (pp. 4 pages). GA, Atlanta: AMER SOC HEMATOLOGY.
DOI WoS1
2021 Lu, L., Dang, P., HoowKok, C., Saunders, V. A., Branford, S., P.Hughes, T., & TYeung, D. (2021). Highly Sensitive Droplet Digital PCR to Identify CML Patients with a High Probability of Achieving Treatment-Free Remission. In BLOOD Vol. 138 (pp. 4 pages). GA, Atlanta: ELSEVIER.
DOI WoS1
2019 Kok, C. H., Liu, L., Yeung, D. T., Saunders, V. A., Dang, P., & Hughes, T. P. (2019). A Combination of <i>CD302</i> gene Expression and 3-Months <i>BCR</i>-<i>ABL1 Level</i> Predicts Inferior Achievement of Deep Molecular Response in CP-CML Patients Treated with Imatinib. In BLOOD Vol. 134 (pp. 3 pages). Orlando, FL: AMER SOC HEMATOLOGY.
DOI WoS1
2016 Asari, K., Heatley, S. L., Sadras, T., Leclercq, T. M., Fitter, S., Kok, C. H., . . . White, D. L. (2016). <i>In Vitro</i> Modeling of Ph-like ALL Fusions Identifies Novel Kinase-Domain Mutations As Mode of TKI-Resistance Implications for Targeted Therapy. In BLOOD Vol. 128 (pp. 5 pages). San Diego, CA: AMER SOC HEMATOLOGY.
DOI WoS1
2016 Pagani, I. S., Kok, C. H., Wang, J., Saunders, V., Goyne, J., McLean, J., . . . Ross, D. M. (2016). MITOCHONDRIAL DNA MUTATIONS IDENTIFY CLONAL HETEROGENEITY IN CHRONIC MYELOID LEUKAEMIA. In HAEMATOLOGICA Vol. 101 (pp. 234). Copenhagen, DENMARK: FERRATA STORTI FOUNDATION.
2016 Pagani, I. S., Kok, C. H., Saunders, V., Goyne, J., McLean, J., VanderHoek, M., . . . Ross, D. M. (2016). The genomic landscape of mitochondrial DNA mutations in chronic myeloid leukaemia.. In European Journal of Human Genetics. Barcelona: Natue Publishing Group.
2015 Kok, C. H., Leclercq, T. M., Watkins, D., Yeung, D. T., Saunders, V. A., White, D. L., & Hughes, T. P. (2015). A 20 Gene Expression Signature That Predicts Early Molecular Response Failure in Chronic Phase CML Patients Treated with Frontline Imatinib. In BLOOD Vol. 126 (pp. 3 pages). Orlando, FL: AMER SOC HEMATOLOGY.
2014 Vandyke, K., Mrozik, K. M., Cheong, C. M., Chow, A. W. S., Kok, C. H., Blaschuk, O., . . . Zannettino, A. C. W. (2014). Identification of an Epithelial-to-Mesenchymal Transition (EMT)-like Programme in t(4;14)-Positive Multiple Myeloma Reveals Novel Targets for Therapeutic Intervention. In BLOOD Vol. 124 (pp. 3 pages). San Francisco, CA: AMER SOC HEMATOLOGY.
WoS1
2011 Watkins, D. B., Kok, C. H., Hughes, T. P., Slader, C., D'Andrea, R., & White, D. L. (2011). Differential Lineage Involvement Between Very Low and Higher OCT-1 Activity Chronic-Phase CML Patients. In BLOOD Vol. 118 (pp. 727). San Diego, CA: AMER SOC HEMATOLOGY.
2011 Wang, J., Hughes, T. P., Kok, C. H., Saunders, V. A., Frede, A., GrootObbink, K., . . . White, D. L. (2011). Non-Steroidal Anti-Inflammatory Drugs and Imatinib; Drug Interactions That May Impact Efficacy. In BLOOD Vol. 118 (pp. 1493-1494). San Diego, CA: AMER SOC HEMATOLOGY.
2011 D'Andrea, R. J., Perugini, M., Kok, C. H., Salerno, D., Danner, S., Bardy, P. G., . . . Lewis, I. D. (2011). Methylation of a Single CpG in the <i>GADD45A</i> Proximal Promoter Is Associated with Poor Survival in Acute Myeloid Leukemia. In BLOOD Vol. 118 (pp. 1511). San Diego, CA: AMER SOC HEMATOLOGY.
2010 Powell, J. A., Thomas, D., Barry, E. F., Kok, C. H., Ma, L. Y., To, L. B., . . . Guthridge, M. A. (2010). TARGETING CELL SURVIVAL PATHWAYS IN ACUTE MYELOID LEUKEMIA. In EXPERIMENTAL HEMATOLOGY Vol. 38 (pp. S60). Melbourne, AUSTRALIA: ELSEVIER SCIENCE INC.
2005 Wilkinson, C., Brown, A., Kok, C., Solomon, P., Goodall, G., Gonda, T., & D'Andrea, M. (2005). Expression profiling of a myeloid cell line model to identify novel transcription factors influencing myeloid cell differentiation proliferation and leukaemia. In Proceedings of 5th Australian Microarray Conference 2005 (pp. unknown). Australia: Unknown.

Year Citation
2022 Shah, M. V., Hahn, C. N., Chhetri, R., Tran, E. N. H., & Hiwase, D. (2022). Integrated personalized prediction model identifies a subgroup of wild-type tp53therapy-related myeloid neoplasm patients with poor outcome. Poster session presented at the meeting of Blood. US: American Society of Hematology.
DOI
2018 Heatley, S. L., Mayne, B. T., McClure, B. J., Kok, C., Sadras, T., Dang, P., . . . White, D. L. (2018). Exploring the genomic diversity of AYA and adult high-risk B-ALL cases by mRNA sequencing. Poster session presented at the meeting of 23rd Congress of European Hematology Association. Stockholm, Sweden.
2018 Heatley, S. L., McClure, B. J., Kok, C., Sadras, T., Dang, P., Galbraith, K., . . . White, D. L. (2018). Exploring the genomic diversity of adult and AYA cases with high-risk B-ALL by mRNA sequencing. Poster session presented at the meeting of NDLR.
2018 Pagani, I. S., Kok, C., Saunders, V., Schwarer, A., Hughes, T. P., White, D. L., & Ross, D. M. (2018). Association of mitochondrial DNA (mtDNA) mutations at diagnosis with treatment response in chronic myeloid leukaemia (CML) patients. Poster session presented at the meeting of NDLR.
2018 Lu, L., Kok, C., Saunders, V., Nievergall, E., White, D. L., & Hughes, T. P. (2018). TGF-α predicts TKI treated CML patients who fail to achieve early molecular response. Poster session presented at the meeting of NDLR.
2018 Downes, C. E., McClure, B. J., Mayne, B. T., Bruning, J. B., Heatley, S. L., Kok, C., . . . White, D. L. (2018). Identification and computational modelling of ruxolitinib resistant mutations in JAK2-rearranged B-cell acute lymphoblastic leukaemia. Poster session presented at the meeting of Poster, Adelaide Protein Group (APG) Student Awards.
2018 Downes, C. E., McClure, B. J., Mayne, B. T., Bruning, J. B., Heatley, S. L., Kok, C., . . . White, D. L. (2018). Identification of ruxolitinib resistance mutations in Pro-B cells driven by a high-risk JAK2 fusion in B-cell acute lymphoblastic leukaemia. Poster session presented at the meeting of Oral, Australian Society for Medical Research (ASMR) SA Meeting.
2018 Downes, C. E., McClure, B. J., Mayne, B. T., Bruning, J. B., Heatley, S. L., Kok, C., . . . White, D. L. (2018). Identification and Characterisation of Ruxolitinib Resistant Mutations in JAK2-rearranged B-cell Acute Lymphoblastic Leukaemia. Poster session presented at the meeting of Poster, Australasian Genomic Technologies Association (AGTA) Annual Conference.
2018 Downes, C. E., McClure, B. J., Mayne, B. T., Bruning, J. B., Heatley, S. L., Kok, C., . . . White, D. L. (2018). Identification of ruxolitinib resistance mutations in Pro-B cells driven by a high-risk B-ALL JAK2-fusion. Poster session presented at the meeting of Poster, Australian and New Zealand Children's Haematology/Oncology Group (ANZCHOG) Annual Scientific Meeting.
2018 Downes, C. E., McClure, B. J., Mayne, B. T., Bruning, J. B., Heatley, S. L., Kok, C., . . . White, D. L. (2018). Identification and computational modelling of ruxolitinib resistant mutations in JAK2-rearranged B-cell acute lymphoblastic leukaemia. Poster session presented at the meeting of Poster, South Australian Health and Medical Research Institute (SAHMRI) Annual Scientific Meeting.
2018 Downes, C. E., McClure, B. J., Mayne, B. T., Bruning, J. B., Heatley, S. L., Kok, C., . . . White, D. L. (2018). Identification and computational modelling of ruxolitinib resistant mutations in JAK2-rearranged B-cell acute lymphoblastic leukaemia. Poster session presented at the meeting of Poster, European Molecular Biology Laboratory (EMBL) Australia Postgraduate Symposium.
2017 McClure, B. J., Heatley, S. L., Kok, C., Sadras, T., An, J., Quek, K., . . . White, D. L. (2017). EP300-ZNF384 is a recurrent fusion gene with distinct gene expression in adolescent/young adult pre-B-ALL patients. Poster session presented at the meeting of ANZCHOG.
2017 Heatley, S. L., Sadras, T., Kok, C., Nievergall, E., Quek, K., Dang, P., . . . White, D. L. (2017). High Prevalence of Relapse in Australian Children with Ph-like Acute Lymphoblastic Leukemia Despite Risk-Adapted Treatment. Poster session presented at the meeting of ANZCHOG.
2017 Asari, K., Sadras, T., Srihari, S., Fitter, S., An, J., Zannettino, A. C., . . . White, D. L. (2017). in vitro Modelling of Ph-like ALL Fusions Uncovers Novel Kinase-domain Mutations as a Mode of TKI-resistance and Potential Consequence of Targeted TKI Therapy. Poster session presented at the meeting of ANZCHOG.
2017 Heatley, S., Sadras, T., Kok, C., Nievergall, E., Quek, K., Dang, P., . . . White, D. (2017). High prevalence of relapse in children with Philadelphia-like acute lymphoblastic leukemia despite risk-adapted treatment. Poster session presented at the meeting of Abstracts of the 57th Annual Meeting of the American Society of Hematology, as published in Blood. Orlando, FL: American Society of Hematology.
DOI WoS2
2017 Downes, C. E., McClure, B. M., Heatley, S. H., Sadras, T. S., Hughes, T. H., Kok, C. K., . . . White, D. W. (2017). Identification and cloning of a novel GOLGA4-JAK2 fusion from an adult patient with B-cell Acute Lymphoblastic Leukaemia. Poster session presented at the meeting of Poster, Australian Society for Medical Research (ASMR) SA Meeting. Adelaide.
2016 Kok, C. H., Watkins, D., Wang, J., Saunders, V., Goyne, J., Pagani, I., . . . White, D. (2016). HIGH GENE EXPRESSION OF HIST1H2AG AND HIST1H4A REDUCES IMATINIB UPTAKE INTO CML CELLS AND PREDICTS POOR RESPONSE TO FRONTLINE IMATINIB THERAPY. Poster session presented at the meeting of HAEMATOLOGICA. Copenhagen, DENMARK: FERRATA STORTI FOUNDATION.
2016 Asari, K., Heatley, S., Leclercq, T., Fitter, S., Kok, C. H., Zannettino, A., . . . White, D. L. (2016). Investigating Modes of Therapeutic Resistance via In Vitro Modelling of TKI-resistant High-Risk Philadelphia-chromosome-positive and Philadelphia-chromosome-like Acute Lymphoblastic Leukaemia. Poster session presented at the meeting of Poster Session. Adelaide, SA.
2016 Kok, C. H., Watkins, D., Wang, J., Saunders, V., Goyne, J., Pagani, I. S., . . . White, D. L. (2016). High Gene Expression of hist1h2ag and hist1h4a Reduces Imatinib Uptake into CML Cells and Predicts Poor Response to Frontline Imatinib Therapy. Poster session presented at the meeting of Poster Session. Melbourne, VIC.
2016 Heatley, S., Sadras, T., McClure, B., Kok, C. H., Dang, P., Nievergall, E., . . . White, D. L. (2016). The Incidence of Ph-like Acute Lymphoblastic Leukaemia (ALL) Increases with Age and is Characterised by Poor Outcome. Poster session presented at the meeting of Poster Session. Melbourne, VIC.
2016 Pagani, I. S., Kok, C. H., Wang, J., Saunders, V., Van der Hoek, M., Heatley, S., . . . Ross, D. (2016). Mitochondrial DNA Mutations at Diagnosis are Linked to Response in TKI treated Chronic Myeloid Leukaemia Patients. Poster session presented at the meeting of Poster Session. Melbourne, VIC.
2016 Lu, L., Saunders, V., Kok, C. H., Leclercq, T., Hughes, T., & White, D. L. (2016). Modelling Ponatinib Resistance In BCR-ABL1+ Cell Lines: Implications For Ponatinib Therapy. Poster session presented at the meeting of Poster Session. Adelaide, SA.
2016 Heatley, S., Sadras, T., kok, C., Venn, N., Revesz, T., Osborn, M., . . . White, D. L. (2016). Australian Children with Ph-like ALL enrolled to ANZCHOG ALL8 had a high prevalence of relapse despite risk adapted treatment. Poster session presented at the meeting of CLS SCIENTIFIC PROGRAMME, Refractory Leukemia and Miscellaneous. Athens.
2016 Sadras, T., Heatley, S., Dang, P., Kok, C., Quek, K., Nievergall, E., . . . White, D. L. (2016). A nine-gene signature defines 2 groups of CRLF2 rearranged B-ALL patients with distinctive genetic features. Poster session presented at the meeting of .. Athens.
2016 Pagani, I. S., Kok, C., Saunders, V., Goyne, J., McLean, J., Vanderhoek, M., . . . Ross, D. (2016). The genomic landscape of mitochondrial DNA mutations in chronic myeloid leukaemia. Poster session presented at the meeting of .. Barcelona, Spain.
2016 Sadras, T., Heatley, S., Kok, C., Quek, K., Dang, P., Nievergall, E., . . . White, D. L. (2016). CRLF2 rearranged B-ALL cases with a Ph-like gene signature are enriched for JAK2 mutations. Poster session presented at the meeting of .. Noosa, QLD.
2016 Lu, L., Saunders, V., Kok, C., Leclercq, T., Hughes, T., & White, D. (2016). Modelling ponatinib resistance in BCR-ABL1+ cell lines: implications for ponatinib therapy. Poster session presented at the meeting of New Directions in Leukaemia Research 2016. Noosa, QLD.
2016 McClure, B., Heatley, S., Sadras, T., Nievergall, E., Kok, C., Dang, P., . . . White, D. L. (2016). Identification of a significantly high prevalence of relapse in Australian children with Ph-like ALL. Poster session presented at the meeting of .. Noosa, QLD.
2016 Pagani, I., Kok, C., Saunders, V., Goyne, J., McLean, J., Vanderhoek, M., . . . White, D. L. (2016). Do mitochondrial mutations in chronic myeloid leukaemia identify a pre-leukemic clone?. Poster session presented at the meeting of .. Noosa, QLD.
2015 Wang, J., Kok, C. H., Leclercq, T. M., Saunders, V. A., D'Andrea, R. J., Hughes, T. P., & White, D. L. (2015). High peroxisome proliferator-activated receptor-gamma (PPAR gamma le) transcriptional activity reduces active influx of imatinib and kinase inhibition in CML cells. Poster session presented at the meeting of Blood. US: American Society of Hematology.
2014 Nievergall, E., Reynolds, J., Kok, C. H., Watkins, D., Biondo, M., Busfield, S. J., . . . Hughes, T. P. (2014). High plasma levels of TGF-α and IL-6 at diagnosis predict early molecular response failure and transformation in CML. Poster session presented at the meeting of Abstract of presentation to 56th ASH Annual Meeting, published in Blood. San Francisco, California: American Society of Hematology.
DOI WoS1
2014 Maung, K. Z., Gray, J. X., Leo, P. J., Bassal, M., Brown, A. L., Bray, S. C., . . . Gonda, T. J. (2014). Whole Exome Sequencing of Acute Myeloid Leukaemia Patients Identifies Somatic and Germline Mutations in Fanconi Anaemia Genes. Poster session presented at the meeting of BLOOD. San Francisco, CA: AMER SOC HEMATOLOGY.
2014 Lu, L., Saunders, V., Kok, C. H., Leclercq, T., Hughes, T. P., & White, D. L. (2014). Modeling Ponatinib Resistance in <i>BCR-ABL1</i>+ Cell Lines: Implications for Ponatinib Resistance in TKI-Resistant and TKI-naive Patients. Poster session presented at the meeting of BLOOD. AMER SOC HEMATOLOGY.
2013 Wang, J., Kok, C. H., D'Andrea, R. J., Hughes, T. P., & White, D. L. (2013). Role Of Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) and Its Ligands In The Regulation Of Functional OCT-1 Activity In CML Cells. Poster session presented at the meeting of BLOOD. New Orleans, LA: AMER SOC HEMATOLOGY.
DOI
2012 D'Andrea, R. J., Perugini, M., Diakiw, S. M., Kok, C. H., Salerno, D., Cummings, N., . . . Lewis, I. D. (2012). Methylation of the Proximal Promoter of <i>GADD45A</i> Is Common in Acute Myeloid Leukemia and Is Associated with Poor Survival. Poster session presented at the meeting of BLOOD. Atlanta, GA: AMER SOC HEMATOLOGY.
DOI
2012 Watkins, D. B., Kok, C. H., D'Andrea, R. J., Hughes, T. P., & White, D. L. (2012). Global DNA methylation analysis identifies key pathway differences between poor (low OCT-1 activity) and standard risk CP-CML patients at diagnosis. Poster session presented at the meeting of “Abstracts of the 54th Annual Meeting and Exposition of the American Society of Hematology, as published in Blood. Atlanta, GA: America Society of Hematology.
2011 Sadras, T., Perugini, M., Ramshaw, H. S., Salerno, D. G., Kok, C. H., Lewis, I. D., . . . D'Andrea, R. J. (2011). IL-3 REGULATES B-CATENIN IN MYELOID CELLS AND ENFORCED EXPRESSION OF B-CATENIN REDUCES THE DEPENDENCY ON IL-3 FOR SURVIVAL. Poster session presented at the meeting of EXPERIMENTAL HEMATOLOGY. ELSEVIER SCIENCE INC.

Date Role Research Topic Program Degree Type Student Load Student Name
2025 Principal Supervisor Identification of germline genomic copy number variations in familial leukemia using next generation sequencing Doctor of Philosophy Doctorate Full Time Mr Yiming Jiang
2025 Principal Supervisor Identification of germline genomic copy number variations in familial leukemia using next generation sequencing Doctor of Philosophy Doctorate Full Time Mr Yiming Jiang
2022 Co-Supervisor - Doctor of Philosophy Doctorate Full Time Ms Muneeza Maqsood

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