| 2023 |
Fanta, B. S., Lenjisa, J., Teo, T., Kou, L., Mekonnen, L., Yang, Y., . . . Wang, S. (2023). Discovery of N,4-Di(1H-pyrazol-4-yl)pyrimidin-2-amine-Derived CDK2 Inhibitors as Potential Anticancer Agents: Design, Synthesis, and Evaluation. Molecules, 28(7), 2951.
DOI Scopus7 WoS6 Europe PMC4 |
| 2022 |
Chen, R., Hassankhani, R., Long, Y., Basnet, S. K. C., Teo, T., Yang, Y., . . . Wang, S. (2022). Discovery of Potent Inhibitors of Cyclin-Dependent Kinases 7 and 9: Design, Synthesis, Structure-Activity Relationship Analysis and Biological Evaluation. Chemmedchem, 18(3), e202200582.
DOI Scopus5 WoS5 Europe PMC5 |
| 2022 |
Teo, T., Kasirzadeh, S., Albrecht, H., Sykes, M. J., Yang, Y., & Wang, S. (2022). An overview of CDK3 in cancer: clinical significance and pharmacological implications. Pharmacological Research, 180, 16 pages.
DOI Scopus12 WoS11 Europe PMC11 |
| 2022 |
Yu, M., Yang, Y., Sykes, M., & Wang, S. (2022). Small-molecule inhibitors of tankyrases as prospective therapeutics for cancer. Journal of Medicinal Chemistry, 65(7), 5244-5273.
DOI Scopus28 Europe PMC27 |
| 2021 |
Yu, M., Teo, T., Yang, Y., Li, M., Long, Y., Philip, S., . . . Wang, S. (2021). Potent and orally bioavailable CDK8 inhibitors: design, synthesis, structure-activity relationship analysis and biological evaluation. European Journal of Medicinal Chemistry, 214, 1-22.
DOI Scopus14 WoS13 Europe PMC11 |
| 2021 |
Yu, M., Long, Y., Yang, Y., Li, M., Teo, T., Noll, B., . . . Wang, S. (2021). Discovery of a potent, highly selective, and orally bioavailable inhibitor of CDK8 through a structure-based optimisation. European Journal of Medicinal Chemistry, 218(113391), 23 pages.
DOI Scopus9 WoS8 Europe PMC8 |
| 2015 |
Teo, T., Yu, M., Yang, Y., Gillam, T., Lam, F., Sykes, M. J., & Wang, S. (2015). Pharmacologic co-inhibition of Mnks and mTORC1 synergistically suppresses proliferation and perturbs cell cycle progression in blast crisis-chronic myeloid leukemia cells. Cancer Letters, 357(2), 612-623.
DOI Scopus43 WoS39 Europe PMC36 |
| 2015 |
Teo, T., Lam, F., Yu, M., Yang, Y., Basnet, S., Albrecht, H., . . . Wang, S. (2015). Pharmacologic inhibition of MNKs in acute myeloid leukemia. Molecular Pharmacology, 88(2), 380-389.
DOI Scopus31 WoS28 Europe PMC23 |
| 2015 |
Teo, T., Yang, Y., Yu, M., Basnet, S., Gillam, T., Hou, J., . . . Wang, S. (2015). An integrated approach for discovery of highly potent and selective Mnk inhibitors: Screening, synthesis and SAR analysis. European Journal of Medicinal Chemistry, 103, 539-550.
DOI Scopus31 WoS27 Europe PMC17 |
| 2015 |
Basnet, S., Diab, S., Schmid, R., Yu, M., Yang, Y., Gillam, T., . . . Wang, S. (2015). Identification of a highly conserved allosteric binding site on Mnk1 and Mnk2 s. Molecular Pharmacology, 88(5), 935-948.
DOI Scopus15 WoS15 Europe PMC10 |
