Santhni Subramaniam

Dr Santhni Subramaniam

School of Pharmacy and Biomedical Science

College of Health

Santhni recently completed her PhD, under the supervision of Prof Clive Prestidge. Her research focussed on improving delivery of antibiotics using nanotechnology for the treatment of recurrent intracellular infections. Prior to this, Santhni completed her Bachelor of Pharmaceutical Science and Bachelor of Biomedical Research (Honours) at UniSA.
Santhni is currently utilising her formulation science knowledge to work on several industry projects. Besides this, Santhni is highly passionate about science outreach and communication. She actively volunteers at STEM events and presents her research to the public through various initiatives, such as Pint of Science.

Year Citation
2025 Wright, L., Wignall, A., Subramaniam, S., Schultz, H. B., Joyce, P., & Prestidge, C. A. (2025). Enhanced oral absorption and biodistribution to submandibular salivary glands of D-limonene in Sprague Dawley rats via a liquid-lipid formulation approach. International Journal of Pharmaceutics, 670(125179), 125179.
DOI Scopus1 WoS1 Europe PMC1
2025 Subramaniam, S., Donnellan, L., Wignall, A., Woodcock, J., Coolen, C., Pitson, S., . . . Joyce, P. (2025). Polymeric-lipid nanoparticles that leverage cationic helper lipids and the protein corona for lung-targeted delivery of a novel anti-cancer drug. Journal of Controlled Release, 388(Pt 1), 15 pages.
DOI
2025 Mahboob, M. B. H., Subramaniam, S., Tait, J. R., Grace, J. L., Elliott, A. G., Floyd, H., . . . Whittaker, M. R. (2025). Cholesterol-terminated cationic lipidated oligomers (CLOs) as a new class of antifungals. Journal of Materials Chemistry B, 13(8), 2776-2795.
DOI
2025 Ahsan, A., Barnes, T. J., Thomas, N., Subramaniam, S., & Prestidge, C. A. (2025). Lipid-based nanocarriers for enhanced gentamicin delivery: a comparative study of liquid crystal nanoparticles and liposomes against Escherichia coli biofilms. Drug Delivery And Translational Research, online(11), 1-22.
DOI
2024 Subramaniam, S., Joyce, P., & Prestidge, C. A. (2024). The biomolecule corona mediates pulmonary delivery of nanomedicine. European Journal of Pharmaceutics and Biopharmaceutics, 202(114420), 1-8.
DOI
2024 Ahsan, A., Thomas, N., Barnes, T. J., Subramaniam, S., Loh, T. C., Joyce, P., & Prestidge, C. A. (2024). Lipid nanocarriers-enabled delivery of antibiotics and antimicrobial adjuvants to overcome bacterial biofilms. Pharmaceutics, 16(3, article no. 396), 1-46.
DOI
2024 Subramaniam, S., Joyce, P., Conn, C. E., & Prestidge, C. A. (2024). Cellular uptake and in vitro antibacterial activity of lipid-based nanoantibiotics are influenced by protein corona. Biomaterials Science, 12(13), 3411-3422.
DOI
2024 Iscaro, J., Yu, H., Martinez, N., Subramaniam, S., Joyce, P., Wang, H., . . . Zhai, J. (2024). Lyotropic liquid crystalline phase nanostructure and cholesterol enhance lipid nanoparticle mediated mRNA transfection in macrophages. Advanced Functional Materials, 34(no. 46, article no. 2405286), 1-15.
DOI Scopus11 WoS13
2024 Subramaniam, S., Joyce, P., Ogunniyi, A. D., Dube, A., Sampson, S. L., Lehr, C. M., & Prestidge, C. A. (2024). Minimum Information for Conducting and Reporting In Vitro Intracellular Infection Assays. ACS Infectious Diseases, 10(2), 337-349.
DOI Scopus6 WoS6 Europe PMC6
2024 Joyce, P., Allen, C. J., Alonso, M. J., Ashford, M., Bradbury, M. S., Germain, M., . . . Santos, H. A. (2024). A translational framework to DELIVER nanomedicines to the clinic. Nature Nanotechnology, 19(11), 1597-1611.
DOI Scopus120 WoS110 Europe PMC74
2023 Subramaniam, S., Elz, A., Wignall, A., Kamath, S., Ariaee, A., Hunter, A., . . . Joyce, P. (2023). Self-emulsifying drug delivery systems (SEDDS) disrupt the gut microbiota and trigger an intestinal inflammatory response in rats. International Journal of Pharmaceutics, 648(123614), 123614-1-123614-10.
DOI Scopus31 WoS27 Europe PMC19
2023 Subramaniam, S., Joyce, P., Donnellan, L., Young, C., Wignall, A., Hoffmann, P., & Prestidge, C. A. (2023). Protein adsorption determines pulmonary cell uptake of lipid-based nanoparticles. Journal of Colloid and Interface Science, 641, 36-47.
DOI Scopus32 WoS31 Europe PMC23
2023 Subramaniam, S., Joyce, P., & Prestidge, C. A. (2023). Liquid crystalline lipid nanoparticles improve the antibacterial activity of tobramycin and vancomycin against intracellular Pseudomonas aeruginosa and Staphylococcus aureus. International Journal of Pharmaceutics, 639(639, article no. 122927), 1-9.
DOI
2023 Subramaniam, S., Kamath, S., Ariaee, A., Prestidge, C., & Joyce, P. (2023). The impact of common pharmaceutical excipients on the gut microbiota. Expert Opinion on Drug Delivery, 20(10), 1297-1394.
DOI
2021 Subramaniam, S., Joyce, P., Thomas, N., & Prestidge, C. A. (2021). Bioinspired drug delivery strategies for repurposing conventional antibiotics against intracellular infections. Advanced Drug Delivery Reviews, 177(113948), 1-23.
DOI
2020 Joyce, P., Ulmefors, H., Maghrebi, S., Subramaniam, S., Wignall, A., Jõemetsa, S., . . . Prestige, C. A. (2020). Enhancing the cellular uptake and antibacterial activity of rifampicin through encapsulation in mesoporous silica nanoparticles. Nanomaterials, 10(4), 1-16.
DOI WoS31 Europe PMC25
2019 Subramaniam, S., Thomas, N., Gustafsson, H., Jambhrunkar, M., Kidd, S. P., & Prestidge, C. A. (2019). Rifampicin-Loaded Mesoporous Silica Nanoparticles for the Treatment of Intracellular Infections.. Antibiotics (Basel, Switzerland), 8(2), 15 pages.
DOI Scopus57 WoS45 Europe PMC39

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