| 2026 |
Maqsood, M., Toubia, J., Wadham, C., Shanmuganathan, N., Shahrin, N. H., Fernandes, A., . . . Branford, S. (2026). Enhanced Detection of Splice-Altering Variants in Hematologic Malignancies Using Targeted RNA-Sequencing Data. Journal of Molecular Diagnostics, 28(1), 39-52.
DOI |
| 2025 |
Shanmuganathan, N., Yeung, D. T., Wadham, C., Fernandes, A., Maqsood, M., Shahrin, N. H., . . . Branford, S. (2025). Impact of ASXL1 at diagnosis in patients with CML receiving frontline potent TKIs: high risk of kinase domain mutations. Blood, 146(23), 2821-2832.
DOI |
| 2024 |
Branford, S., Fernandes, A., Shahrin, N. H., Maqsood, M., Shanmuganathan, N., & Wadham, C. (2024). Beyond BCR::ABL1-the role of genomic analyses in the management of CML. Journal of the National Comprehensive Cancer Network : JNCCN, 22(1), 1-9.
DOI Scopus9 WoS9 Europe PMC6 |
| 2023 |
Shanmuganathan, N., Wadham, C., Shahrin, N., Feng, J., Thomson, D., Wang, P., . . . Branford, S. (2023). Impact of additional genetic abnormalities at diagnosis of chronic myeloid leukemia for first-line imatinib-treated patients receiving proactive treatment intervention. Haematologica, 108(9), 2380-2395.
DOI Scopus19 WoS18 Europe PMC15 |
| 2022 |
Shanmuganathan, N., Wadham, C., Thomson, D., Shahrin, N. H., Vignaud, C., Obourn, V., . . . Branford, S. (2022). RNA-Based Targeted Gene Sequencing Improves the Diagnostic Yield of Mutant Detection in Chronic Myeloid Leukemia.. The Journal of molecular diagnostics : JMD, 24(7), 803-822.
DOI Scopus8 WoS6 Europe PMC5 |
| 2022 |
Shahrin, N. H., Wadham, C., & Branford, S. (2022). Defining Higher-Risk Chronic Myeloid Leukemia: Risk Scores, Genomic Landscape, and Prognostication.. Current hematologic malignancy reports, 264(6), 171-180.
DOI Scopus8 WoS5 Europe PMC4 |
| 2022 |
Lau, L. M. S., Mayoh, C., Xie, J., Barahona, P., MacKenzie, K. L., Wong, M., . . . Marshall, G. M. (2022). In vitro and in vivo drug screens of tumor cells identify novel therapies for high-risk child cancer. EMBO Molecular Medicine, 14(4), e14608.
DOI Scopus33 Europe PMC31 |
| 2020 |
Fordham, A. M., Xie, J., Gifford, A. J., Wadham, C., Morgan, L. T., Mould, E. V. A., . . . Trahair, T. N. (2020). CD30 and ALK combination therapy has high therapeutic potency in RANBP2-ALK-rearranged epithelioid inflammatory myofibroblastic sarcoma. British Journal of Cancer, 123(7), 1101-1113.
DOI Scopus30 Europe PMC22 |
| 2020 |
Aji, G., Huang, Y., Ng, M. L., Wang, W., Lan, T., Li, M., . . . Qi, Y. (2020). Regulation of hepatic insulin signaling and glucose homeostasis by sphingosine kinase 2. Proceedings of the National Academy of Sciences of the United States of America, 117(39), 24434-24442.
DOI Scopus44 Europe PMC36 |
| 2020 |
Somers, K., Kosciolek, A., Bongers, A., El-Ayoubi, A., Karsa, M., Mayoh, C., . . . Henderson, M. J. (2020). Potent antileukemic activity of curaxin CBL0137 against MLL-rearranged leukemia. International Journal of Cancer, 146(7), 1902-1916.
DOI Scopus31 Europe PMC30 |
| 2020 |
Thomson, D. W., Shahrin, N. H., Wang, P. P. S., Wadham, C., Shanmuganathan, N., Scott, H. S., . . . Branford, S. (2020). Aberrant RAG-mediated recombination contributes to multiple structural rearrangements in lymphoid blast crisis of chronic myeloid leukemia. Leukemia, 34(8), 2051-2063.
DOI Scopus36 WoS34 Europe PMC29 |
| 2018 |
Branford, S., Wang, P., Yeung, D. T., Thomson, D., Purins, A., Wadham, C., . . . Hughes, T. P. (2018). Integrative genomic analysis reveals cancer-associated mutations at diagnosis of CML in patients with high-risk disease. Blood, 132(9), 948-961.
DOI Scopus169 WoS158 Europe PMC140 |
| 2018 |
Tsoli, M., Wadham, C., Pinese, M., Failes, T., Joshi, S., Mould, E., . . . Ziegler, D. S. (2018). Integration of genomics, high throughput drug screening, and personalized xenograft models as a novel precision medicine paradigm for high risk pediatric cancer. Cancer Biology and Therapy, 19(12), 1078-1087.
DOI Scopus21 Europe PMC14 |
| 2017 |
Ng, M. L., Wadham, C., & Sukocheva, O. A. (2017). The role of sphingolipid signalling in diabetes-associated pathologies. International journal of molecular medicine, 39(2), 243-252.
DOI Scopus73 Europe PMC63 |
| 2015 |
Zhang, H., Chen, Y., Wadham, C., McCaughan, G. W., Keane, F. M., & Gorrell, M. D. (2015). Dipeptidyl peptidase 9 subcellular localization and a role in cell adhesion involving focal adhesion kinase and paxillin. Biochimica et biophysica acta-molecular cell research, 1853(2), 470-480.
DOI Scopus36 Europe PMC25 |
| 2015 |
Sukocheva, O., Wadham, C., Gamble, J., & Xia, P. (2015). Sphingosine-1-phosphate receptor 1 transmits estrogens' effects in endothelial cells. Steroids, 104, 237-245.
DOI Scopus32 Europe PMC32 |
| 2014 |
Sukocheva, O., & Wadham, C. (2014). Role of sphingolipids in oestrogen signalling in breast cancer cells: an update. Journal of endocrinology, 220(3), R25-R35.
DOI Scopus28 Europe PMC27 |
| 2014 |
Saletta, F., Wadham, C., Ziegler, D. S., Marshall, G. M., Haber, M., McCowage, G., . . . Byrne, J. A. (2014). Molecular profiling of childhood cancer: biomarkers and novel therapies. BBA clinical, 1, 59-77.
DOI Scopus36 |
| 2013 |
Sukocheva, O., Wadham, C., & Xia, P. (2013). Estrogen defines the dynamics and destination of transactivated EGF receptor in breast cancer cells: role of S1P(3) receptor and Cdc42. Experimental cell research, 319(4), 455-465.
DOI Scopus28 Europe PMC24 |
| 2012 |
Wadham, C., Parker, A., Wang, L., & Xia, P. (2012). High glucose attenuates protein S-nitrosylation in endothelial cells: role of oxidative stress (Diabetes (2007) 56, (2715-2721)). Diabetes, 61(3), 759.
DOI |
| 2011 |
Xia, P., & Wadham, C. (2011). Sphingosine 1-phosphate, a key mediator of the cytokine network: juxtacrine signaling. Cytokine & growth factor reviews, 22(1), 45-53.
DOI Scopus44 Europe PMC35 |
| 2010 |
Zhang, N., Qi, Y., Wadham, C., Wang, L., Warren, A., Di, W., & Xia, P. (2010). FTY720 induces necrotic cell death and autophagy in ovarian cancer cells: a protective role of autophagy. Autophagy, 6(8), 1157-1167.
DOI Scopus113 |
| 2009 |
Wadham, C., Parker, A., Wang, L., & Xia, P. (2009). Erratum: High glucose attenuates protein S-nitrosylation in endothelial cells: role of oxidative stress (Diabetes (2007) 56, (2715-2721)). Diabetes, 58(9), 2162.
DOI |
| 2009 |
Wadham, C., & Mangoni, A. A. (2009). Dimethylarginine dimethylaminohydrolase regulation: a novel therapeutic target in cardiovascular disease. Expert opinion on drug metabolism & toxicology, 5(3), 303-319.
DOI Scopus53 Europe PMC41 |
| 2009 |
Sukocheva, O., Wadham, C., & Xia, P. (2009). Role of sphingolipids in the cytoplasmic signaling of estrogens. Steroids, 74(7), 562-567.
DOI Scopus24 Europe PMC21 |
| 2007 |
Wadham, C., Parker, A., Wang, L., & Xia, P. (2007). High glucose attenuates protein S-nitrosylation in endothelial cells - Role of oxidative stress. Diabetes, 56(11), 2715-2721.
DOI Scopus77 Europe PMC56 |
| 2007 |
Belle, L., Wadham, C., Crocker, L., Lardelli, M., & Khew-Goodall, Y. (2007). The protein tyrosine phosphatase Pez regulates TGFβ, epithelial–mesenchymal transition, and organ development. Journal of Cell Biology, 178(7), 1223-1235.
DOI Scopus75 WoS71 Europe PMC63 |
| 2006 |
Sukocheva, O., Wadham, C., Holmes, A., Albanese, N., Verrier, E., Feng, F., . . . Xia, P. (2006). Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: the role of sphingosine kinase-1. Journal of Cell Biology, 173(2), 301-310.
DOI Scopus195 Europe PMC170 |
| 2005 |
Wang, L., Xing, X., Holmes, A., Wadham, C., Gamble, J., Vadas, M., & Xia, P. (2005). Activation of the sphingosine kinase-signaling pathway by high glucose mediates the proinflammatory phenotype of endothelial cells. Circulation Research, 97(9), 891-899.
DOI Scopus68 Europe PMC54 |
| 2005 |
Khew-Goodall, Y., & Wadham, C. (2005). A perspective on regulation of cell-cell adhesion and epithelial-mesenchymal transition: Known and novel. Cells Tissues Organs, 179(1-2), 81-86.
DOI Scopus19 WoS16 Europe PMC15 |
| 2004 |
Verrier, E., Wang, L., Wadham, C., Albanese, N., Hahn, C., Gamble, J., . . . Xia, P. (2004). PPARg agonists ameliorate endothelial cell activation via inhibition of diacylglycerol-protein kinase C signaling pathway: Role of diacylglycerol kinase. Circulation Research, 94(11), 1515-1522.
DOI Scopus101 WoS95 Europe PMC81 |
| 2004 |
Wadham, C., Albanese, N., Roberts, J., Wang, L., Bagley, C., Gamble, J., . . . Xia, P. (2004). High-density lipoproteins neutralize C-reactive protein proinflammatory activity. Circulation, 109(17), 2116-2122.
DOI Scopus162 Europe PMC110 |
| 2003 |
Wadham, C., Gamble, J., Vadas, M., & Khew-Goodall, Y. (2003). The protein tyrosine phosphatase pez is a major phosphatase of adherens junctions and dephosphorylates b-catenin. Molecular Biology of the Cell, 14(6), 2520-2529.
DOI Scopus82 WoS78 Europe PMC74 |
| 2000 |
Wadham, C., Gamble, J., Vadas, M., & Khew-Goodall, Y. (2000). Translocation of protein tyrosine phosphatase Pez/PTPD2/PTP36 to the nucleus is associated with induction of cell proliferation. Journal of Cell Science, 113(17), 3117-3123.
DOI Scopus42 WoS42 Europe PMC38 |
| 1999 |
Khew-Goodall, Y., Wadham, C., Stein, B., Gamble, J., & Vadas, M. (1999). Stat6 activation is essential for interleukin-4 induction of P-selectin transcription in juman umbilical vein endothelial cells. Arteriosclerosis, Thrombosis and Vascular Biology, 19(6), 1421-1429.
DOI Scopus52 WoS46 Europe PMC35 |
| 1996 |
Wadham, C., Winter, H., & Schuller, K. A. (1996). Regulation of soybean nodule phosphoenolpyruvate carboxylase in vivo. Physiologia Plantarum, 97(3), 531-535.
DOI Scopus18 |
